Suman Kumar Dhar
Indian biologist
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Biology
Suman Kumar Dhar's Degrees
- Masters Biotechnology Delhi University
- Bachelors Biotechnology University of Calcutta
Why Is Suman Kumar Dhar Influential?
(Suggest an Edit or Addition)According to Wikipedia, Suman Kumar Dhar is an Indian molecular biologist and a professor at the Special Centre for Molecular Medicine of Jawaharlal Nehru University. He is known for his studies on the DNA replication and cell cycle regulation in Helicobacter pylori and Plasmodium falciparum, two pathogens affecting humans. An elected fellow of the National Academy of Sciences, India, Indian National Science Academy and the Indian Academy of Sciences, he is also a recipient of the National Bioscience Award for Career Development of the Department of Biotechnology in 2010. The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards, in 2012, for his contributions to biological sciences.
Suman Kumar Dhar's Published Works
Published Works
- Inhibition of eukaryotic DNA replication by geminin binding to Cdt1. (2000) (633)
- Replication from oriP of Epstein-Barr Virus Requires Human ORC and Is Inhibited by Geminin (2001) (292)
- Xenopus Mcm10 binds to origins of DNA replication after Mcm2-7 and stimulates origin binding of Cdc45. (2002) (200)
- Mcm10 and And-1/CTF4 recruit DNA polymerase α to chromatin for initiation of DNA replication (2007) (192)
- Mcm10 and And-1/CTF4 recruit DNA polymerase alpha to chromatin for initiation of DNA replication. (2007) (124)
- Rvb1p and Rvb2p Are Essential Components of a Chromatin Remodeling Complex That Regulates Transcription of over 5% of Yeast Genes* (2001) (116)
- Architecture of the Human Origin Recognition Complex* (2001) (112)
- A dimerized coiled-coil domain and an adjoining part of geminin interact with two sites on Cdt1 for replication inhibition. (2004) (83)
- Identification and Characterization of the Human ORC6 Homolog* (2000) (75)
- Elongation by RNA polymerase II on chromatin templates requires topoisomerase activity. (2003) (74)
- Molecular Cloning of Apicoplast-Targeted Plasmodium falciparum DNA Gyrase Genes: Unique Intrinsic ATPase Activity and ATP-Independent Dimerization of PfGyrB Subunit (2007) (62)
- Nucleotide sequence organisation and analysis of the nuclear ribosomal DNA circle of the protozoan parasite Entamoeba histolytica. (1994) (61)
- Nicotinamide inhibits Plasmodium falciparum Sir2 activity in vitro and parasite growth. (2008) (57)
- Sequence-specific recognition of DNA minor groove by an NIR-fluorescence switch-on probe and its potential applications (2015) (56)
- Purification and characterization of the N-terminal nucleotide binding domain of an ABC drug transporter of Candida albicans: uncommon cysteine 193 of Walker A is critical for ATP hydrolysis. (2003) (52)
- Functional characterization of Helicobacter pylori DnaB helicase. (2003) (50)
- Subsets of Human Origin Recognition Complex (ORC) Subunits Are Expressed in Non-proliferating Cells and Associate with Non-ORC Proteins* (2000) (48)
- A Thiazole Coumarin (TC) Turn-On Fluorescence Probe for AT-Base Pair Detection and Multipurpose Applications in Different Biological Systems (2014) (44)
- Plasmodium falciparum origin recognition complex subunit 5: functional characterization and role in DNA replication foci formation (2008) (38)
- The role of N-terminus of Plasmodium falciparum ORC1 in telomeric localization and var gene silencing (2012) (36)
- Potent Antimalarial Activity of Acriflavine In Vitro and In Vivo (2014) (36)
- Three-Dimensional Structure of N-Terminal Domain of DnaB Helicase and Helicase-Primase Interactions in Helicobacter pylori (2009) (34)
- Molecular mechanism of action of major Helicobacter pylori virulence factors (2003) (33)
- Helicobacter pylori DnaB helicase can bypass Escherichia coli DnaC function in vivo. (2005) (33)
- A multitude of circular DNAs exist in the nucleus of Entamoeba histolytica. (1995) (30)
- Expression and characterization of human malaria parasite Plasmodium falciparum origin recognition complex subunit 1. (2005) (28)
- An atypical cyclin-dependent kinase controls Plasmodium falciparum proliferation rate (2013) (27)
- Crystal Structure and Mode of Helicase Binding of the C-Terminal Domain of Primase from Helicobacter pylori (2013) (25)
- Stable transfection of Entamoeba histolytica trophozoites by lipofection. (1997) (23)
- Histone H3K9 acetylation level modulates gene expression and may affect parasite growth in human malaria parasite Plasmodium falciparum (2014) (23)
- Single-stranded DNA binding protein from human malarial parasite Plasmodium falciparum is encoded in the nucleus and targeted to the apicoplast (2010) (21)
- The domain structure of Helicobacter pylori DnaB helicase: the N-terminal domain can be dispensable for helicase activity whereas the extreme C-terminal region is essential for its function (2007) (21)
- Functional dissection of proliferating-cell nuclear antigens (1 and 2) in human malarial parasite Plasmodium falciparum: possible involvement in DNA replication and DNA damage response. (2015) (21)
- Replication initiates at multiple dispersed sites in the ribosomal DNA plasmid of the protozoan parasite Entamoeba histolytica (1996) (20)
- Regulation of Plasmodium falciparum Origin Recognition Complex subunit 1 (PfORC1) function through phosphorylation mediated by CDK‐like kinase PK5 (2015) (19)
- Functional Dissection of the Catalytic Carboxyl-Terminal Domain of Origin Recognition Complex Subunit 1 (PfORC1) of the Human Malaria Parasite Plasmodium falciparum (2009) (18)
- Helicobacter pylori chromosomal DNA replication: Current status and future perspectives (2011) (18)
- Helicobacter pylori single‐stranded DNA binding protein – functional characterization and modulation of H. pylori DnaB helicase activity (2009) (18)
- A Unique 45-Amino-Acid Region in the Toprim Domain of Plasmodium falciparum Gyrase B Is Essential for Its Activity (2009) (16)
- Intracellular Locations of Replication Proteins and the Origin of Replication during Chromosome Duplication in the Slowly Growing Human Pathogen Helicobacter pylori (2013) (15)
- Analogous expression pattern of Plasmodium falciparum replication initiation proteins PfMCM4 and PfORC1 during the asexual and sexual stages of intraerythrocytic developmental cycle. (2006) (15)
- Designing novel inhibitors against histone acetyltransferase (HAT: GCN5) of Plasmodium falciparum. (2017) (14)
- DNA binding activity of Helicobacter pylori DnaB helicase: the role of the N‐terminal domain in modulating DNA binding activities (2012) (13)
- Identification and characterization of ARS‐like sequences as putative origin(s) of replication in human malaria parasite Plasmodium falciparum (2017) (11)
- ‘Modulation of the enzymatic activities of replicative helicase (DnaB) by interaction with Hp0897: a possible mechanism for helicase loading in Helicobacter pylori’ (2016) (10)
- Targeting the β‐clamp in Helicobacter pylori with FDA‐approved drugs reveals micromolar inhibition by diflunisal (2017) (10)
- Plasmodium falciparum: epigenetic control of var gene regulation and disease. (2013) (10)
- Regulation of DNA replication proteins in parasitic protozoans: possible role of CDK-like kinases (2016) (9)
- Role of Chromatin assembly factor 1 in DNA replication of Plasmodium falciparum. (2018) (9)
- Synthesis of Novel Ciprofloxacin-Based Hybrid Molecules toward Potent Antimalarial Activity. (2020) (8)
- Design, Synthesis and Evaluation of Bifunctional Acridinine−Naphthalenediimide Redox-Active Conjugates as Antimalarials (2016) (8)
- Plasmodium falciparum GCN5 acetyltransferase follows a novel proteolytic processing pathway that is essential for its function (2019) (8)
- Antibacterial action of acriflavine hydrochloride for eradication of the gastric pathogen Helicobacter pylori. (2020) (7)
- DNA replication during intra-erythrocytic stages of human malarial parasite Plasmodium falciparum (2012) (7)
- Ribosomal DNA Fragments Enhance the Stability of Transfected DNA in Entamoeba histolytica (1998) (6)
- In silico identification of inhibitors against Plasmodium falciparum histone deacetylase 1 (PfHDAC-1) (2018) (6)
- Identification of putative Z‐ring‐associated proteins, involved in cell division in human pathogenic bacteria Helicobacter pylori (2016) (5)
- Molecular characterization and expression profile of an alternate proliferating cell nuclear antigen homolog PbPCNA2 in Plasmodium berghei (2019) (5)
- Plasmodium falciparum single-stranded DNA-binding protein (PfSSB) interacts with PfPrex helicase and modulates its activity. (2014) (4)
- Helicobacter pylori shows asymmetric and polar cell divisome assembly associated with DNA replisome (2018) (3)
- Identification of a novel trafficking pathway exporting a replication protein, Orc2 to nucleus via classical secretory pathway in Plasmodium falciparum. (2018) (3)
- Role of tyrosine residue (Y213) in nuclear retention of PCNA1 in human malaria parasite Plasmodium falciparum (2018) (3)
- Potent in vivo antimalarial activity of water-soluble artemisinin nano-preparations (2020) (3)
- Role of unique loops in oligomerization and ATPase function of Plasmodium falciparum gyrase B (2021) (1)
- Helicobacter pylori helicase loader protein Hp0897 shows unique functions of N- and C-terminal regions. (2019) (1)
- ORIS: An interactive software tool for prediction of replication origin in prokaryotic genomes (2019) (1)
- Regulation of DNA replication proteins in parasitic protozoans: possible role of CDK-like kinases (2016) (1)
- Stable transfection of E. histolytica trophozoites by lipofection (1997) (0)
- Screening of E. coli β-clamp Inhibitors Revealed that Few Inhibit Helicobacter pylori More Effectively: Structural and Functional Characterization (2018) (0)
- Studies on replication and maintenance of the ribosomal DNA circle of Entamoeba histolytica (1997) (0)
- Helicase-Primase Interactions and their Structural Studies in Helicobacter Pylori (2011) (0)
- DNA, DNA Replication, and Aging (2020) (0)
- Bioprospecting microbial diversity: intellectual property rights issues. (2016) (0)
- Functional characterization of Helicobacter pylori (2003) (0)
- Role of PfMYST in DNA replication in Plasmodium falciparum. (2022) (0)
- CLONING, EXPRESSION, PURIFICATION AND CRYSTALLIZATION OF A NOVEL GLCNAC METABOLIC PROTEIN, GIG2 (DUF1479) FROM PATHOGENIC FUNGUS CANDIDA ALBICANS (2017) (0)
- Identification of a Novel Trafficking Pathway Exporting Protein to the Nucleus via Classical Secretory Pathway in Plasmodium falciparum (2015) (0)
- A ~35 kDa polypeptide from insect cells binds to yeast ACS like elements in the presence of ATP (2002) (0)
- The tetrameric structure of Plasmodium falciparum phosphoglycerate mutase is critical for optimal enzymatic activity (2022) (0)
- 1 Architecture of the Human Origin Recognition Complex (2001) (0)
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