Sundeep Khosla
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Computer Science
Sundeep Khosla's Degrees
- Bachelors Computer Science Stanford University
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(Suggest an Edit or Addition)Sundeep Khosla's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Osteoporosis: now and the future (2011) (1835)
- Sex steroids and the construction and conservation of the adult skeleton. (2002) (1744)
- Bisphosphonate‐Associated Osteonecrosis of the Jaw: Report of a Task Force of the American Society for Bone and Mineral Research (2007) (1562)
- Minireview: the OPG/RANKL/RANK system. (2001) (1447)
- The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs (2015) (1299)
- Bisphosphonates: mechanism of action and role in clinical practice. (2008) (1188)
- The Roles of Osteoprotegerin and Osteoprotegerin Ligand in the Paracrine Regulation of Bone Resorption (2000) (1174)
- A Unitary Model for Involutional Osteoporosis: Estrogen Deficiency Causes Both Type I and Type II Osteoporosis in Postmenopausal Women and Contributes to Bone Loss in Aging Men (1998) (1122)
- Senolytics Improve Physical Function and Increase Lifespan in Old Age (2018) (1086)
- Relationship of serum sex steroid levels and bone turnover markers with bone mineral density in men and women: a key role for bioavailable estrogen. (1998) (963)
- Fat tissue, aging, and cellular senescence (2010) (840)
- Population‐Based Study of Age and Sex Differences in Bone Volumetric Density, Size, Geometry, and Structure at Different Skeletal Sites (2004) (822)
- Leptin acts on human marrow stromal cells to enhance differentiation to osteoblasts and to inhibit differentiation to adipocytes. (1999) (752)
- Receptor activator of nuclear factor kappaB ligand and osteoprotegerin regulation of bone remodeling in health and disease. (2008) (743)
- Role of RANK ligand in mediating increased bone resorption in early postmenopausal women. (2003) (736)
- Relative contributions of testosterone and estrogen in regulating bone resorption and formation in normal elderly men. (2000) (713)
- Estrogen stimulates gene expression and protein production of osteoprotegerin in human osteoblastic cells. (1999) (678)
- Targeting cellular senescence prevents age-related bone loss in mice (2017) (626)
- Interleukin-1β and tumor necrosis factor-α, but not interleukin-6, stimulate osteoprotegerin ligand gene expression in human osteoblastic cells (1999) (589)
- Estrogen and the skeleton (2012) (552)
- Effects of Sex and Age on Bone Microstructure at the Ultradistal Radius: A Population‐Based Noninvasive In Vivo Assessment (2005) (533)
- Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease (2019) (524)
- DHEA in elderly women and DHEA or testosterone in elderly men. (2006) (520)
- Relationship of serum sex steroid levels to longitudinal changes in bone density in young versus elderly men. (2001) (518)
- Regulation of bone formation by osteoclasts involves Wnt/BMP signaling and the chemokine sphingosine-1-phosphate (2008) (480)
- A Population‐Based Assessment of Rates of Bone Loss at Multiple Skeletal Sites: Evidence for Substantial Trabecular Bone Loss in Young Adult Women and Men (2007) (479)
- Stimulation of Osteoprotegerin Ligand and Inhibition of Osteoprotegerin Production by Glucocorticoids in Human Osteoblastic Lineage Cells: Potential Paracrine Mechanisms of Glucocorticoid-Induced Osteoporosis1. (1999) (471)
- Stimulation of osteoprotegerin ligand and inhibition of osteoprotegerin production by glucocorticoids in human osteoblastic lineage cells: potential paracrine mechanisms of glucocorticoid-induced osteoporosis. (1999) (468)
- Incidence of childhood distal forearm fractures over 30 years: a population-based study. (2003) (467)
- Osteoporosis treatment: recent developments and ongoing challenges. (2017) (454)
- In Vivo Assessment of Bone Quality in Postmenopausal Women With Type 2 Diabetes (2014) (425)
- Cost-effective osteoporosis treatment thresholds: the United States perspective (2008) (424)
- The clinical diagnosis of osteoporosis: a position statement from the National Bone Health Alliance Working Group (2014) (414)
- Implications of absolute fracture risk assessment for osteoporosis practice guidelines in the USA (2008) (405)
- Oral bisphosphonate-induced osteonecrosis: risk factors, prediction of risk using serum CTX testing, prevention, and treatment. (2008) (398)
- Circulating osteoblast-lineage cells in humans. (2005) (393)
- Incidence of Primary Hyperparathyroidism in Rochester, Minnesota, 1993–2001: An Update on the Changing Epidemiology of the Disease (2005) (383)
- Mechanisms of sex steroid effects on bone. (2005) (383)
- Primary Hyperparathyroidism and the Risk of Fracture: A Population‐Based Study (1999) (374)
- Building bone to reverse osteoporosis and repair fractures. (2008) (362)
- Relationship of Bone Turnover to Bone Density and Fractures (1997) (356)
- Fracture Risk in Type 2 Diabetes: Update of a Population‐Based Study (2008) (352)
- Epidemiology of Sarcopenia (2000) (344)
- Osteoprotegerin production by human osteoblast lineage cells is stimulated by vitamin D, bone morphogenetic protein-2, and cytokines. (1998) (332)
- Osteoporosis in men. (1995) (328)
- Relationship between body composition and bone mass in women (1996) (321)
- The role of the immune system in the pathophysiology of osteoporosis (2005) (320)
- Role of serum leptin, insulin, and estrogen levels as potential mediators of the relationship between fat mass and bone mineral density in men versus women. (2001) (313)
- Leptin reduces ovariectomy-induced bone loss in rats. (2001) (311)
- Pathophysiology of age-related bone loss and osteoporosis. (2005) (309)
- The Unitary Model for Estrogen Deficiency and the Pathogenesis of Osteoporosis: Is a Revision Needed? (2010) (296)
- Androgen therapy in women: an Endocrine Society Clinical Practice guideline. (2006) (293)
- Identification of Senescent Cells in the Bone Microenvironment (2016) (291)
- Estrogen and the Male Skeleton (2002) (289)
- Relation of Age, Gender, and Bone Mass to Circulating Sclerostin Levels in Women and Men (2010) (276)
- Effects of age and estrogen status on serum parathyroid hormone levels and biochemical markers of bone turnover in women: a population-based study. (1997) (274)
- Trends in Fracture Incidence: A Population‐Based Study Over 20 Years (2014) (269)
- Bone Structure at the Distal Radius During Adolescent Growth (2009) (266)
- The Rise and Fall of Primary Hyperparathyroidism: A Population-Based Study in Rochester, Minnesota, 1965-1992 (1997) (261)
- The actions and interactions of sex steroids and growth factors/cytokines on the skeleton. (1999) (256)
- Survival after the diagnosis of hyperparathyroidism: a population-based study. (1998) (253)
- Effects of parathyroid hormone treatment on circulating sclerostin levels in postmenopausal women. (2010) (243)
- A Crisis in the Treatment of Osteoporosis (2016) (241)
- Changes in Runx2/Cbfa1 Expression and Activity During Osteoblastic Differentiation of Human Bone Marrow Stromal Cells (2003) (237)
- Benefits and risks of bisphosphonate therapy for osteoporosis. (2012) (235)
- Role of calcium intake in modulating age-related increases in parathyroid function and bone resorption. (1996) (229)
- Physiology of bone loss. (2010) (228)
- Interleukin-1beta and tumor necrosis factor-alpha, but not interleukin-6, stimulate osteoprotegerin ligand gene expression in human osteoblastic cells. (1999) (222)
- Effects of immunosuppressants on receptor activator of NF-kappaB ligand and osteoprotegerin production by human osteoblastic and coronary artery smooth muscle cells. (2001) (221)
- Role of Low Levels of Endogenous Estrogen in Regulation of Bone Resorption in Late Postmenopausal Women (2002) (216)
- Mediators of the biphasic responses of bone to intermittent and continuously administered parathyroid hormone (2003) (215)
- Correlates of Osteoprotegerin Levels in Women and Men (2002) (212)
- Robust QCT/FEA Models of Proximal Femur Stiffness and Fracture Load During a Sideways Fall on the Hip (2011) (211)
- Effect of Blockade of TNF‐α and Interleukin‐1 Action on Bone Resorption in Early Postmenopausal Women (2007) (206)
- Effect of estrogen versus testosterone on circulating osteoprotegerin and other cytokine levels in normal elderly men. (2002) (197)
- Structural Determinants of Vertebral Fracture Risk (2007) (195)
- The role of cellular senescence in ageing and endocrine disease (2020) (194)
- The expression of osteoprotegerin and RANK ligand and the support of osteoclast formation by stromal-osteoblast lineage cells is developmentally regulated. (2000) (190)
- Epidemiology and clinical features of osteoporosis in young individuals. (1994) (189)
- Regulation of Circulating Sclerostin Levels by Sex Steroids in Women and in Men (2010) (188)
- Mesenchymal stem cells for bone repair and metabolic bone diseases. (2009) (185)
- Effects of estrogen therapy on bone marrow adipocytes in postmenopausal osteoporotic women (2008) (181)
- Contribution of In Vivo Structural Measurements and Load/Strength Ratios to the Determination of Forearm Fracture Risk in Postmenopausal Women (2007) (181)
- Epidemiology of sarcopenia. (2000) (179)
- Cortical and trabecular bone microarchitecture as an independent predictor of incident fracture risk in older women and men in the Bone Microarchitecture International Consortium (BoMIC): a prospective study. (2019) (179)
- Relationship of serum leptin levels with body composition and sex steroid and insulin levels in men and women. (2000) (177)
- Bisphosphonate Associated Osteonecrosis of the Jaw (2008) (173)
- Canadian consensus practice guidelines for bisphosphonate associated osteonecrosis of the jaw. (2008) (171)
- Pathogenesis of age-related bone loss in humans. (2013) (170)
- Update in male osteoporosis. (2010) (169)
- Osteocalcin expression by circulating endothelial progenitor cells in patients with coronary atherosclerosis. (2008) (164)
- Calcium infusion suggests a "set-point" abnormality of parathyroid gland function in familial benign hypercalcemia and more complex disturbances in primary hyperparathyroidism. (1993) (164)
- Remodeling and Vascular Spaces in Bone (2006) (164)
- Update on estrogens and the skeleton. (2010) (162)
- Cortical Porosity Identifies Women With Osteopenia at Increased Risk for Forearm Fractures (2014) (162)
- Cathepsin K Inhibitors for Osteoporosis: Biology, Potential Clinical Utility, and Lessons Learned (2017) (160)
- Quantification of GDF11 and Myostatin in Human Aging and Cardiovascular Disease. (2016) (158)
- Estrogen receptor isoform‐specific regulation of endogenous gene expression in human osteoblastic cell lines expressing either ERα or ERβ (2003) (155)
- Role of parathyroid hormone in mediating nocturnal and age-related increases in bone resorption. (1995) (154)
- Relationship of Volumetric BMD and Structural Parameters at Different Skeletal Sites to Sex Steroid Levels in Men (2004) (152)
- Androgen effects on bone metabolism: recent progress and controversies. (1999) (150)
- Relationship of intestinal calcium absorption to 1,25-dihydroxyvitamin D [1,25(OH)2D] levels in young versus elderly women: evidence for age-related intestinal resistance to 1,25(OH)2D action. (2000) (149)
- Age-Dependence of Femoral Strength in White Women and Men (2009) (149)
- Female reproductive system and bone. (2010) (148)
- Mechanism of renal calcium conservation with estrogen replacement therapy in women in early postmenopause--a clinical research center study. (1995) (148)
- Loss of heterozygosity suggests multiple genetic alterations in pheochromocytomas and medullary thyroid carcinomas. (1991) (147)
- Androgens and bone (2009) (147)
- The Expression of Osteoprotegerin and RANK Ligand and the Support of Osteoclast Formation by Stromal-Osteoblast Lineage Cells Is Developmentally Regulated* *This work was supported by Grant AG-04875 from the National Institute on Aging. (2000) (145)
- Fracture Risk in Monoclonal Gammopathy of Undetermined Significance (2003) (143)
- A bone structural basis for fracture risk in diabetes. (2008) (142)
- Determinants of bone strength and quality in diabetes mellitus in humans. (2016) (138)
- Fracture risk following bilateral orchiectomy. (2003) (138)
- Age‐ and Sex‐Specific Differences in the Factor of Risk for Vertebral Fracture: A Population‐Based Study Using QCT (2006) (138)
- Regulation of Bone Metabolism by Sex Steroids. (2018) (137)
- Emerging therapeutic opportunities for skeletal restoration (2011) (134)
- Senolytics reduce coronavirus-related mortality in old mice (2021) (132)
- Characterization of circulating osteoblast lineage cells in humans. (2007) (132)
- Estrogen receptor α and β heterodimers exert unique effects on estrogen- and tamoxifen- dependent gene expression in human U2OS osteosarcoma cells (2005) (132)
- Clinical review 144: Estrogen and the male skeleton. (2002) (131)
- Relative Influence of Physical Activity, Muscle Mass and Strength on Bone Density (2000) (129)
- Fracture risk among patients with urolithiasis: a population-based cohort study. (1998) (126)
- Is vitamin D a determinant of muscle mass and strength? (2011) (125)
- Parathyroid hormone-related protein and hypercalcemia secondary to massive mammary hyperplasia. (1990) (125)
- Secondary Fracture Prevention: Consensus Clinical Recommendations from a Multistakeholder Coalition (2019) (125)
- Fracture Risk After Bilateral Oophorectomy in Elderly Women (2003) (123)
- Skeletal Metabolism, Fracture Risk, and Fracture Outcomes in Type 1 and Type 2 Diabetes (2016) (120)
- Towards a diagnostic and therapeutic consensus in male osteoporosis (2011) (118)
- Effects of Raloxifene, a Selective Estrogen Receptor Modulator, on Bone Turnover Markers and Serum Sex Steroid and Lipid Levels in Elderly Men (2001) (117)
- Assessing forearm fracture risk in postmenopausal women (2010) (116)
- Skeletal changes through the lifespan—from growth to senescence (2015) (116)
- Cross-Sectional Versus Longitudinal Evaluation of Bone Loss in Men and Women (2000) (116)
- Circulating levels of cytokines that modulate bone resorption: Effects of age and menopause in women (1994) (115)
- Contributions of bone density and structure to fracture risk assessment in men and women (2005) (114)
- For estimating creatinine clearance measuring muscle mass gives better results than those based on demographics. (2009) (111)
- Population‐Based Analysis of the Relationship of Whole Bone Strength Indices and Fall‐Related Loads to Age‐ and Sex‐Specific Patterns of Hip and Wrist Fractures (2005) (110)
- Hormonal and biochemical determinants of trabecular microstructure at the ultradistal radius in women and men. (2006) (109)
- Wnt Signaling Inhibits Osteoclast Differentiation by Activating Canonical and Noncanonical cAMP/PKA Pathways (2016) (108)
- Regulation of osteoclastogenesis and RANK expression by TGF‐β1 (2001) (107)
- Phytoestrogen genistein acts as an estrogen agonist on human osteoblastic cells through estrogen receptors α and β (2003) (107)
- Senolytic Drugs: Reducing Senescent Cell Viability to Extend Health Span. (2020) (107)
- Higher muscle protein synthesis in women than men across the lifespan, and failure of androgen administration to amend age‐related decrements (2009) (104)
- Clinical Use of Quantitative Computed Tomography-Based Finite Element Analysis of the Hip and Spine in the Management of Osteoporosis in Adults: the 2015 ISCD Official Positions-Part II. (2015) (104)
- In vitro and in vivo detection of somatostatin receptors in pheochromocytomas and paragangliomas. (1992) (103)
- Effects of Body Size and Skeletal Site on the Estimated Prevalence of Osteoporosis in Women and Men (2000) (102)
- Circulating cytokine levels in osteoporotic and normal women. (1994) (102)
- Multicenter precision of cortical and trabecular bone quality measures assessed by high‐resolution peripheral quantitative computed tomography (2013) (101)
- Bone turnover across the menopause transition: correlations with inhibins and follicle-stimulating hormone. (2006) (101)
- Bone density and structure in healthy postmenopausal women treated with exemestane for the primary prevention of breast cancer: a nested substudy of the MAP.3 randomised controlled trial. (2012) (98)
- Skeletal muscle mass is associated with bone geometry and microstructure and serum insulin‐like growth factor binding protein‐2 levels in adult women and men (2012) (97)
- The endogenous selective estrogen receptor modulator 27-hydroxycholesterol is a negative regulator of bone homeostasis. (2010) (97)
- Relationship of age to bone microstructure independent of areal bone mineral density (2012) (96)
- Effects of age on bone mRNA levels of sclerostin and other genes relevant to bone metabolism in humans. (2014) (95)
- Relation of Serum Serotonin Levels to Bone Density and Structural Parameters in Women (2009) (95)
- Relation of Vertebral Deformities to Bone Density, Structure, and Strength (2010) (94)
- Bone microarchitecture in ankylosing spondylitis and the association with bone mineral density, fractures, and syndesmophytes (2013) (91)
- The oxysterol, 27-hydroxycholesterol, links cholesterol metabolism to bone homeostasis through its actions on the estrogen and liver X receptors. (2011) (91)
- Cellular senescence in bone. (2019) (91)
- Bone fragility in men - where are we? (2006) (91)
- Assessment of Gene Regulation by Bone Morphogenetic Protein 2 in Human Marrow Stromal Cells Using Gene Array Technology (2001) (91)
- Prospective randomized study of effects of unopposed estrogen replacement therapy on markers of coagulation and inflammation in postmenopausal women. (2001) (89)
- Genetic Testing in the Diagnosis and Management of Multiple Endocrine Neoplasia Type II (1995) (89)
- Clinical performance of parathyroid hormone immunometric assays. (1992) (87)
- Clinical Use of Quantitative Computed Tomography-Based Advanced Techniques in the Management of Osteoporosis in Adults: the 2015 ISCD Official Positions-Part III. (2015) (87)
- Emerging Role of Circulating Calcifying Cells in the Bone-Vascular Axis (2012) (87)
- Effects of androgens on the insulin-like growth factor system in an androgen-responsive human osteoblastic cell line. (1999) (87)
- Effects of the circadian variation in serum cortisol on markers of bone turnover and calcium homeostasis in normal postmenopausal women. (1998) (87)
- Estrogens and Bone Health in Men (2001) (87)
- Potential Role of Pancreatic and Enteric Hormones in Regulating Bone Turnover (2005) (86)
- Fracture risk in primary hyperparathyroidism. (2002) (86)
- Relationship of volumetric bone density and structural parameters at different skeletal sites to sex steroid levels in women. (2005) (86)
- Inhibiting Cellular Senescence: A New Therapeutic Paradigm for Age-Related Osteoporosis (2018) (85)
- Evidence that type I osteoporosis results from enhanced responsiveness of bone to estrogen deficiency (2003) (85)
- Concise Review: Insights from Normal Bone Remodeling and Stem Cell‐Based Therapies for Bone Repair (2010) (84)
- Identification of osteoclast-osteoblast coupling factors in humans reveals links between bone and energy metabolism (2020) (84)
- Circulating Cells with Osteogenic Potential (2006) (84)
- Addressing the Crisis in the Treatment of Osteoporosis: A Path Forward. (2017) (83)
- Clinical practice. Osteopenia. (2007) (83)
- Effects of suppression of follicle-stimulating hormone secretion on bone resorption markers in postmenopausal women. (2010) (83)
- Clinical Use of Quantitative Computed Tomography (QCT) of the Hip in the Management of Osteoporosis in Adults: the 2015 ISCD Official Positions-Part I. (2015) (83)
- Relationship of testosterone and osteocalcin levels during growth (2011) (81)
- Estrogen receptor isoform-specific regulation of endogenous gene expression in human osteoblastic cell lines expressing either ERalpha or ERbeta. (2003) (81)
- Myostatin as a mediator of sarcopenia versus homeostatic regulator of muscle mass: insights using a new mass spectrometry-based assay (2015) (81)
- The impact of the new National Bone Health Alliance (NBHA) diagnostic criteria on the prevalence of osteoporosis in the USA (2017) (81)
- Muscle strength in Osteoporotic versus normal women (2005) (80)
- Relationship of estrogen receptor genotypes to bone mineral density and to rates of bone loss in men. (2004) (79)
- Effects of estrogen on osteoprogenitor cells and cytokines/bone-regulatory factors in postmenopausal women. (2011) (79)
- Increasing options for the treatment of osteoporosis. (2009) (78)
- Abnormalities of parathyroid hormone secretion in elderly women that are reversible by short term therapy with 1,25-dihydroxyvitamin D3. (1994) (78)
- Estrogen regulation of human osteoblast function is determined by the stage of differentiation and the estrogen receptor isoform (2001) (78)
- Addressing the Crisis in the Treatment of Osteoporosis: A Path Forward (2017) (77)
- Sclerostin levels during growth in children (2012) (77)
- The Anti‐Androgen Hydroxyflutamide and Androgens Inhibit Interleukin‐6 Production by an Androgen‐Responsive Human Osteoblastic Cell Line (1999) (77)
- Reducing Senescent Cell Burden in Aging and Disease. (2020) (76)
- A Potentially Deleterious Role of IGFBP‐2 on Bone Density in Aging Men and Women (2004) (76)
- Estrogen receptor alpha and beta heterodimers exert unique effects on estrogen- and tamoxifen-dependent gene expression in human U2OS osteosarcoma cells. (2005) (76)
- Dose-response of estrogen on bone versus the uterus in ovariectomized mice. (2004) (76)
- Sphingosine 1-Phosphate (S1P) Receptors 1 and 2 Coordinately Induce Mesenchymal Cell Migration through S1P Activation of Complementary Kinase Pathways* (2013) (75)
- Regulation of osteoprotegerin production by androgens and anti-androgens in human osteoblastic lineage cells. (2002) (75)
- Comparison of sex steroid measurements in men by immunoassay versus mass spectroscopy and relationships with cortical and trabecular volumetric bone mineral density (2008) (74)
- Coronary endothelial dysfunction in humans is associated with coronary retention of osteogenic endothelial progenitor cells. (2010) (73)
- Skeletal Effects of Estrogen Are Mediated by Opposing Actions of Classical and Nonclassical Estrogen Receptor Pathways (2005) (73)
- TGF-β induces Wnt10b in osteoclasts from female mice to enhance coupling to osteoblasts. (2013) (73)
- Effects of loss of steroid receptor coactivator-1 on the skeletal response to estrogen in mice. (2004) (72)
- Non-suppressible parathyroid hormone secretion is related to gland size in uremic secondary hyperparathyroidism. (1996) (71)
- Osteopenia in adults with a history of juvenile rheumatoid arthritis. A population based study. (2002) (71)
- Parathyroid hormone plus alendronate--a combination that does not add up. (2003) (71)
- Subcutaneous administration of insulin-like growth factor (IGF)-II/IGF binding protein-2 complex stimulates bone formation and prevents loss of bone mineral density in a rat model of disuse osteoporosis. (2002) (71)
- Microarchitecture and Peripheral BMD are Impaired in Postmenopausal White Women With Fracture Independently of Total Hip T‐Score: An International Multicenter Study (2016) (71)
- Technical note: Recommendations for a standard procedure to assess cortical bone at the tissue-level in vivo using impact microindentation (2016) (68)
- Role of circulating osteogenic progenitor cells in calcific aortic stenosis. (2012) (68)
- Skeletal stem/osteoprogenitor cells: Current concepts, alternate hypotheses, and relationship to the bone remodeling compartment (2008) (67)
- Treatment-related changes in bone mineral density as a surrogate biomarker for fracture risk reduction: meta-regression analyses of individual patient data from multiple randomised controlled trials. (2020) (67)
- Bone Strength and Structural Deficits in Children and Adolescents With a Distal Forearm Fracture Resulting From Mild Trauma (2014) (66)
- Transforming growth factor beta 1 induces CXCL16 and leukemia inhibitory factor expression in osteoclasts to modulate migration of osteoblast progenitors. (2013) (66)
- Epidemiology of adrenal tumours in Olmsted County, Minnesota, USA: a population-based cohort study. (2020) (65)
- Proximal femoral density distribution and structure in relation to age and hip fracture risk in women (2013) (64)
- Relationship of adiposity to bone volumetric density and microstructure in men and women across the adult lifespan. (2013) (64)
- Osteocalcin positive CD133+/CD34-/KDR+ progenitor cells as an independent marker for unstable atherosclerosis. (2012) (64)
- High Serum IGFBP‐2 Is Predictive of Increased Bone Turnover in Aging Men and Women (2007) (64)
- Cytokine production in the bone marrow microenvironment: failure to demonstrate estrogen regulation in early postmenopausal women. (1996) (64)
- Effects of estrogen on bone mRNA levels of sclerostin and other genes relevant to bone metabolism in postmenopausal women. (2014) (64)
- Bone microstructural changes revealed by high-resolution peripheral quantitative computed tomography imaging and elevated DKK1 and MIP-1α levels in patients with MGUS. (2011) (62)
- Leptin-central or peripheral to the regulation of bone metabolism? (2002) (62)
- Parathyroid hormone-related peptide in lactation and in umbilical cord blood. (1990) (62)
- Applications of a New Handheld Reference Point Indentation Instrument Measuring Bone Material Strength. (2013) (62)
- Human embryonic stem cell-derived CD34+ cells function as MSC progenitor cells. (2010) (61)
- Association of hip strength estimates by finite‐element analysis with fractures in women and men (2011) (61)
- Sclerostin is expressed in osteoclasts from aged mice and reduces osteoclast‐mediated stimulation of mineralization (2013) (61)
- Osteoclast TGF‐β Receptor Signaling Induces Wnt1 Secretion and Couples Bone Resorption to Bone Formation (2016) (60)
- Two Years of Treatment With Dehydroepiandrosterone Does Not Improve Insulin Secretion, Insulin Action, or Postprandial Glucose Turnover in Elderly Men or Women (2007) (60)
- Mutations in the RET protooncogene in sporadic pheochromocytomas. (1995) (59)
- The Immunosuppressant Rapamycin, Alone or with Transforming Growth Factor-b, Enhances Osteoclast Differentiation of RAW264.7 Monocyte-Macrophage Cells in the Presence of RANK-Ligand (2002) (59)
- Osteoporosis and Hip Fracture Risk From Routine Computed Tomography Scans: The Fracture, Osteoporosis, and CT Utilization Study (FOCUS) (2018) (59)
- Relationship of sympathetic activity to bone microstructure, turnover, and plasma osteopontin levels in women. (2012) (59)
- Independent Roles of Estrogen Deficiency and Cellular Senescence in the Pathogenesis of Osteoporosis: Evidence in Young Adult Mice and Older Humans (2019) (59)
- Role of estrogen deficiency in pathogenesis of secondary hyperparathyroidism and increased bone resorption in elderly women. (1997) (58)
- Effects of gonadal and adrenal androgens in a novel androgen‐responsive human osteoblastic cell line (1998) (58)
- Effects of Age and Estrogen on Skeletal Gene Expression in Humans as Assessed by RNA Sequencing (2015) (58)
- Effects of physiological variations in circulating insulin levels on bone turnover in humans. (2011) (58)
- Polyphenol-rich cranberry juice has a neutral effect on endothelial function but decreases the fraction of osteocalcin-expressing endothelial progenitor cells (2013) (58)
- The assembly of the adult skeleton during growth and maturation: implications for senile osteoporosis. (1999) (57)
- Targeted Reduction of Senescent Cell Burden Alleviates Focal Radiotherapy‐Related Bone Loss (2020) (56)
- The circumstances, orientations, and impact locations of falls in community-dwelling older women. (2017) (56)
- Pathophysiologic importance of visceral adipose tissue in women with heart failure and preserved ejection fraction. (2020) (53)
- Hdac3 Deficiency Increases Marrow Adiposity and Induces Lipid Storage and Glucocorticoid Metabolism in Osteochondroprogenitor Cells (2016) (53)
- Hormonal and systemic regulation of sclerostin. (2017) (53)
- Response of Bipotential Human Marrow Stromal Cells to Insulin-Like Growth Factors: Effect on Binding Protein Production, Proliferation, and Commitment to Osteoblasts and Adipocytes1. (1999) (52)
- Targeting Bone Remodeling for the Treatment of Osteoporosis: Summary of the Proceedings of an ASBMR Workshop (2009) (51)
- Legumain Regulates Differentiation Fate of Human Bone Marrow Stromal Cells and Is Altered in Postmenopausal Osteoporosis (2017) (51)
- Does Reduced Skeletal Loading Account for Age‐Related Bone Loss? (2006) (50)
- Managing fragility fractures during the COVID-19 pandemic (2020) (50)
- Identification of multiple endocrine neoplasia, type 2 gene carriers using linkage analysis and analysis of the RET proto-oncogene. (1994) (50)
- Estrogen receptor beta isoform-specific induction of transforming growth factor beta-inducible early gene-1 in human osteoblast cells: an essential role for the activation function 1 domain. (2008) (50)
- Secondary osteoporosis and the risk of distal forearm fractures in men and women. (2002) (49)
- Sympathetic &bgr;1-adrenergic signaling contributes to regulation of human bone metabolism (2018) (49)
- Neutrophils induce paracrine telomere dysfunction and senescence in ROS‐dependent manner (2021) (49)
- Serum Biomarker Profile Associated With High Bone Turnover and BMD in Postmenopausal Women (2008) (48)
- Treatment‐Related Changes in Bone Turnover and Fracture Risk Reduction in Clinical Trials of Anti‐Resorptive Drugs: A Meta‐Regression (2018) (48)
- Wnt10b activates the wnt, notch, and NFκB pathways in u2os osteosarcoma cells (2011) (48)
- Fracture risk after surgery for peptic ulcer disease: a population-based cohort study. (1999) (47)
- Osteoporosis: gender differences and similarities (1999) (47)
- Effects of estrogen with micronized progesterone on cortical and trabecular bone mass and microstructure in recently postmenopausal women. (2013) (47)
- Role of extracellular matrix in insulin-like growth factor (IGF) binding protein-2 regulation of IGF-II action in normal human osteoblasts. (2003) (47)
- Osteoporosis assessment by whole body region vs. site-specific DXA (2005) (47)
- Biomechanical Computed Tomography analysis (BCT) for clinical assessment of osteoporosis (2020) (47)
- Comprehensive Assessment of Osteoporosis and Bone Fragility with CT Colonography. (2016) (47)
- Body composition during childhood and adolescence: relations to bone strength and microstructure. (2014) (46)
- Abdominal Aortic Calcification, BMD, and Bone Microstructure: A Population‐Based Study (2008) (46)
- Improved Fracture Risk Assessment Based on Nonlinear Micro‐Finite Element Simulations From HRpQCT Images at the Distal Radius (2013) (46)
- Mutual antagonism of estrogen receptors alpha and beta and their preferred interactions with steroid receptor coactivators in human osteoblastic cell lines. (2003) (46)
- Effects of chronic estrogen treatment on modulating age‐related bone loss in female mice (2010) (46)
- Secondary osteoporosis and the risk of vertebral deformities in women. (1999) (45)
- Assessing fracture risk using gradient boosting machine (GBM) models (2012) (45)
- Phytoestrogen genistein acts as an estrogen agonist on human osteoblastic cells through estrogen receptors alpha and beta. (2003) (45)
- Effects of adjuvant exemestane versus anastrozole on bone mineral density for women with early breast cancer (MA.27B): a companion analysis of a randomised controlled trial. (2014) (45)
- The Limited Clinical Utility of Testosterone, Estradiol, and Sex Hormone Binding Globulin Measurements in the Prediction of Fracture Risk and Bone Loss in Older Men (2017) (44)
- Estrogen and bone: insights from estrogen-resistant, aromatase-deficient, and normal men. (2008) (44)
- Relationship of femoral neck areal bone mineral density to volumetric bone mineral density, bone size, and femoral strength in men and women (2011) (44)
- Regulation of osteoclastogenesis and RANK expression by TGF-beta1. (2001) (44)
- Estrogen Receptor Isoform‐Specific Induction of Progesterone Receptors in Human Osteoblasts (2002) (44)
- Editorial: Sex hormone binding globulin: inhibitor or facilitator (or both) of sex steroid action? (2006) (44)
- The role of estrogens in men and androgens in women. (2003) (43)
- A distal forearm fracture in childhood is associated with an increased risk for future fragility fractures in adult men, but not women (2013) (43)
- Characterization of mesenchymal progenitor cells isolated from human bone marrow by negative selection. (2012) (42)
- Estrogen and Fracture Risk in Men (2008) (42)
- LPS-induced premature osteocyte senescence: Implications in inflammatory alveolar bone loss and periodontal disease pathogenesis. (2020) (42)
- New selective estrogen and androgen receptor modulators (2009) (42)
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- Response of bipotential human marrow stromal cells to insulin-like growth factors: effect on binding protein production, proliferation, and commitment to osteoblasts and adipocytes. (1999) (42)
- New Insights Into Androgen and Estrogen Receptor Regulation of the Male Skeleton (2015) (42)
- Validation of a CT-Derived Method for Osteoporosis Screening in IBD Patients Undergoing Contrast-Enhanced CT Enterography (2014) (42)
- The Type I/Type II Model for Involutional Osteoporosis: Update and Modification Based on New Observations (2001) (41)
- Aromatase inhibitor-associated bone fractures: a case-cohort GWAS and functional genomics. (2014) (41)
- Accelerated osteocyte senescence and skeletal fragility in mice with type 2 diabetes. (2020) (40)
- TGF-β mediates suppression of adipogenesis by estradiol through connective tissue growth factor induction. (2012) (39)
- Cytokine‐specific induction of the TGF‐β inducible early gene (TIEG): Regulation by specific members of the TGF‐β family (2000) (39)
- Genetic testing in medullary thyroid carcinoma syndromes: mutation types and clinical significance. (1997) (39)
- A new gene set identifies senescent cells and predicts senescence-associated pathways across tissues (2021) (38)
- Deletion of Estrogen Receptor Beta in Osteoprogenitor Cells Increases Trabecular but Not Cortical Bone Mass in Female Mice (2016) (38)
- What Accounts for Rib Fractures in Older Adults? (2011) (37)
- Osteoporosis in Men—Consensus is Premature (2004) (37)
- Automatic multi-parametric quantification of the proximal femur with quantitative computed tomography. (2015) (37)
- Effects of bisphosphonate treatment on circulating osteogenic endothelial progenitor cells in postmenopausal women. (2013) (37)
- Circulating osteogenic cells: characterization and relationship to rates of bone loss in postmenopausal women. (2010) (37)
- Coronary microvascular endothelial dysfunction is an independent predictor of development of osteoporosis in postmenopausal women (2014) (37)
- Evaluation of a Prediction Model for Long‐Term Fracture Risk (2004) (36)
- Fracture risk in men with prostate cancer: A population‐based study (2011) (36)
- Estrogen therapy and coronary-artery calcification. (2007) (36)
- Patients with an HbA1c in the prediabetic and diabetic range have higher numbers of circulating cells with osteogenic and endothelial progenitor cell markers. (2012) (36)
- Determinants of Bone Material Strength and Cortical Porosity in Patients with Type 2 Diabetes Mellitus. (2020) (36)
- Male osteoporosis. (2012) (36)
- Role of Hormonal Changes in the Pathogenesis of Osteoporosis in Men (2004) (35)
- Bone growth and turnover in progesterone receptor knockout mice. (2008) (35)
- Structural patterns of the proximal femur in relation to age and hip fracture risk in women. (2013) (35)
- A defect in renal calcium conservation may contribute to the pathogenesis of postmenopausal osteoporosis. (1998) (34)
- Fracture Incidence and Characteristics in Young Adults Aged 18 to 49 Years: A Population‐Based Study (2017) (34)
- Examination of nuclear receptor expression in osteoblasts reveals rorβ as an important regulator of osteogenesis (2012) (34)
- The comparability of HR-pQCT bone measurements is improved by scanning anatomically standardized regions (2017) (34)
- Effects of intermittent parathyroid hormone treatment on osteoprogenitor cells in postmenopausal women. (2011) (34)
- Sex- and Age-Related Differences in Bone Microarchitecture in Men Relative to Women Assessed by High-Resolution Peripheral Quantitative Computed Tomography (2012) (34)
- Surrogates for Fracture Endpoints in Clinical Trials (2003) (33)
- Operator variability in scan positioning is a major component of HR-pQCT precision error and is reduced by standardized training (2016) (33)
- Induction of fracture repair by mesenchymal cells derived from human embryonic stem cells or bone marrow (2011) (33)
- System for the analysis of whole-bone strength from helical CT images (2004) (32)
- Odanacatib: Location and timing are everything (2012) (32)
- Fatty acid metabolism in the elderly: effects of dehydroepiandrosterone and testosterone replacement in hormonally deficient men and women. (2009) (32)
- Corrigendum to ‘Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease’ EBioMedicine 47 (2019) 446–456 (2020) (31)
- Idiopathic osteoporosis--is the osteoblast to blame? (1997) (31)
- The bone and beyond: A shift in calcium (2011) (31)
- Estrogen receptor beta: the antimechanostat? (2006) (31)
- Distinct effects of loss of classical estrogen receptor signaling versus complete deletion of estrogen receptor alpha on bone. (2011) (31)
- Update on the pathogenesis and treatment of skeletal fragility in type 2 diabetes mellitus (2021) (30)
- Use of site-specific antibodies to characterize the circulating form of big insulin-like growth factor II in patients with hepatitis C-associated osteosclerosis. (2002) (30)
- Three-dimensional structural analysis of the proximal femur in an age-stratified sample of women. (2013) (30)
- Global transcriptional profiling using RNA sequencing and DNA methylation patterns in highly enriched mesenchymal cells from young versus elderly women. (2015) (30)
- Fracture risk in women with breast cancer: A population‐based study (2012) (29)
- Aging, Obesity, and the Incidence of Diverticulitis: A Population‐Based Study (2018) (29)
- Is familial hyperparathyroidism a unique disease? (1997) (29)
- Osteogenic monocytes within the coronary circulation and their association with plaque vulnerability in patients with early atherosclerosis. (2015) (29)
- Effects of loss of classical estrogen response element signaling on bone in male mice. (2007) (29)
- Fractures following thyroidectomy in women: a population-based cohort study. (2000) (29)
- miR‐219a‐5p Regulates Rorβ During Osteoblast Differentiation and in Age‐related Bone Loss (2018) (28)
- Dissection of Estrogen Receptor Alpha Signaling Pathways in Osteoblasts Using RNA-Sequencing (2014) (28)
- Regulation of Bone Turnover by Sex Steroids in Men (2007) (27)
- Insulin-Like Growth Factor System Abnormalities in Hepatitis C-Associated Osteosclerosis (1998) (27)
- Age-dependent renal cortical microvascular loss in female mice. (2012) (27)
- Skeletal Consequences of Deletion of Steroid Receptor Coactivator-2/Transcription Intermediary Factor-2* (2009) (26)
- Estrogen Receptor Isoform-specific Regulation of the Retinoblastoma-binding Protein 1 (RBBP1) Gene (2006) (26)
- Cytokine-specific induction of the TGF-beta inducible early gene (TIEG): regulation by specific members of the TGF-beta family. (2000) (26)
- Circulating osteogenic endothelial progenitor cell counts: new biomarker for the severity of coronary artery disease. (2017) (26)
- Forum on aging and skeletal health: Summary of the proceedings of an ASBMR workshop (2011) (25)
- Development and characterization of a conditionally immortalized human osteoblastic cell line stably transfected with the human androgen receptor gene (1997) (25)
- Voxel size dependency, reproducibility and sensitivity of an in vivo bone loading estimation algorithm (2016) (25)
- Editorial: Idiopathic osteoporosis - Is the osteoblast to blame? (1997) (25)
- Isolation and characterization of human osteoblasts from needle biopsies without in vitro culture (2014) (24)
- The skeletal response to estrogen is impaired in female but not in male steroid receptor coactivator (SRC)-1 knock out mice. (2008) (24)
- Fisetin for COVID‐19 in skilled nursing facilities: Senolytic trials in the COVID era (2021) (24)
- Osteoporosis update from the 2010 santa fe bone symposium. (2011) (24)
- Placebo-controlled trials in osteoporosis--proceeding with caution. (2010) (23)
- Potential Extensions of the US FRAX Algorithm (2012) (22)
- Bone diseases: Romosozumab — on track or derailed? (2017) (22)
- Estrogen inhibits Dlk1/FA1 production: A potential mechanism for estrogen effects on bone turnover (2011) (22)
- A fragment of the hypophosphatemic factor, MEPE, requires inducible cyclooxygenase‐2 to exert potent anabolic effects on normal human marrow osteoblast precursors (2004) (22)
- Native osteoprotegerin gene transfer inhibits the development of murine osteolytic bone disease induced by tumor xenografts. (2004) (22)
- Sex‐specific effects of dehydroepiandrosterone (DHEA) on bone mineral density and body composition: A pooled analysis of four clinical trials (2018) (22)
- Idiopathic osteoporosis: a heterogeneous entity. (1998) (22)
- Better tools for assessing osteoporosis. (2012) (21)
- Diminished Bone Strength Is Observed in Adult Women and Men Who Sustained a Mild Trauma Distal Forearm Fracture During Childhood (2014) (21)
- Osteoporosis detection in postmenopausal women using axial transmission multi-frequency bone ultrasonometer: clinical findings. (2014) (21)
- Estrogen Deficiency, Postmenopausal Osteoporosis, and Age-Related Bone Loss (2013) (21)
- Mutual Enhancement of Differentiation of Osteoblasts and Osteocytes Occurs Through Direct Cell–Cell Contact (2014) (21)
- Treatment options for osteoporosis. (1995) (21)
- Systemic assessments utilizing saliva: part 2 osteoporosis and use of saliva to measure bone turnover. (2006) (20)
- Can vitamin D metabolite measurements facilitate a “treat-to-target” paradigm to guide vitamin D supplementation? (2015) (20)
- Effect of estrogen replacement therapy on parathyroid hormone secretion in elderly postmenopausal women (2003) (20)
- Role of parathyroid hormone in mediating age-related changes in bone resorption in men (2003) (20)
- Loss of ERE binding activity by estrogen receptor‐α alters basal and estrogen‐stimulated bone‐related gene expression by osteoblastic cells (2008) (19)
- Insulin-mediated FFA suppression is associated with triglyceridemia and insulin sensitivity independent of adiposity. (2012) (19)
- Evaluation of cross-sectional and longitudinal changes in volumetric bone mineral density in postmenopausal women using single- versus dual-energy quantitative computed tomography. (2018) (19)
- Factors associated with proximal femur fracture determined in a large cadaveric cohort. (2018) (19)
- The Role of Sex Steroids in the Pathogenesis of Osteoporosis (2013) (18)
- Transforming growth factor-beta 1 induces growth inhibition of a human medullary thyroid carcinoma cell line despite an increase in steady state c-myc messenger ribonucleic acid levels. (1994) (18)
- Oestrogen, bones and men: when testosterone just isn't enough (2002) (18)
- Autoimmune hemolytic anemia with both cold and warm autoantibodies. (1985) (18)
- Increased Cortical Porosity and Reduced Trabecular Density Are Not Necessarily Synonymous With Bone Loss and Microstructural Deterioration (2018) (17)
- Examination of ERα signaling pathways in bone of mutant mouse models reveals the importance of ERE-dependent signaling. (2012) (17)
- The impact of the new National Bone Health Alliance (NBHA) diagnostic criteria on the prevalence of osteoporosis in the United States: supplementary presentation (2017) (17)
- Is nitroglycerin a novel and inexpensive treatment for osteoporosis? (2011) (17)
- Update on primary osteoporosis. (1997) (17)
- DHEA in elderly women and DHEA or testosterone in elderly men (2007) (17)
- Primary osteoporosis in men: role of sex steroid deficiency. (2000) (16)
- Safety of hospital discharge before return of bowel function after elective colorectal surgery (2020) (16)
- Effects of Estrogen and Testosterone on Resting Energy Expenditure in Older Men (2010) (16)
- Gorham-Stout disease (phantom bone) of the shoulder girdle. (1999) (16)
- Characterization of cellular senescence in aging skeletal muscle (2022) (16)
- A DNA binding mutation in estrogen receptor‐α Leads to suppression of Wnt signaling via β‐catenin destabilization in osteoblasts (2012) (15)
- Corrigendum: Targeting cellular senescence prevents age-related bone loss in mice (2017) (15)
- Effects of testosterone and estradiol on cutaneous vasodilation during local warming in older men. (2007) (15)
- Periodontal Disease and Senescent Cells: New Players for an Old Oral Health Problem? (2020) (15)
- Targeted clearance of p21‐ but not p16‐positive senescent cells prevents radiation‐induced osteoporosis and increased marrow adiposity (2022) (15)
- Familial medullary thyroid cancer and prominent corneal nerves: clinical and genetic analysis. (1995) (15)
- Use of renal function measurements for assessing fracture risk in postmenopausal women. (2008) (15)
- Estrogen action on bone marrow osteoclast lineage cells of postmenopausal women in vivo (2009) (15)
- The crosstalk between bone remodeling and energy metabolism: A translational perspective. (2022) (14)
- Modulation of fracture healing by the transient accumulation of senescent cells (2021) (14)
- Net ankle quasi-stiffness is influenced by walking speed but not age for older adult women. (2018) (13)
- Regarding “True Gold or Pyrite: A Review of Reference Point Indentation for Assessing Bone Mechanical Properties In Vivo” (2015) (13)
- Potential anabolic effects of androgens on bone. (2004) (13)
- Osteoprotection Through the Deletion of the Transcription Factor Rorβ in Mice (2018) (13)
- Aspirin and fracture risk: a systematic review and exploratory meta-analysis of observational studies (2020) (13)
- Male mice with elevated C-type natriuretic peptide-dependent guanylyl cyclase-B activity have increased osteoblasts, bone mass and bone strength. (2020) (13)
- Senescent cells exacerbate chronic inflammation and contribute to periodontal disease progression in old mice. (2020) (13)
- Validation of a novel, rapid, high precision sclerostin assay not confounded by sclerostin fragments. (2018) (12)
- Longitudinal changes in lumbar bone mineral density distribution may increase the risk of wedge fractures. (2013) (12)
- Immunoradiometric assay for intact human osteocalcin(1-49) without cross-reactivity to breakdown products. (1999) (12)
- Androgens, estrogens, and bone turnover in men. (2003) (12)
- Mutual antagonism of estrogen receptors (cid:1) and (cid:2) and their preferred interactions with steroid receptor coactivators in human osteoblastic cell lines (2003) (12)
- The Impact of Mild Autonomous Cortisol Secretion on Bone Turnover Markers. (2020) (12)
- Identification of Rorβ targets in cultured osteoblasts and in human bone. (2013) (12)
- Secondary Fracture Prevention: Consensus Clinical Recommendations From a Multistakeholder Coalition. (2020) (12)
- Measurement of gene expression following cryogenic mu-CT scanning of human iliac crest biopsies. (2003) (11)
- Estrogen, selective estrogen receptor modulators and now mechanism-specific ligands of the estrogen or androgen receptor? (2003) (11)
- The relationships between compensatory stepping thresholds and measures of gait, standing postural control, strength, and balance confidence in older women. (2018) (11)
- Patient-Centered Network of Learning Health Systems: Developing a resource for clinical translational research (2017) (11)
- What do we tell our patients about calcium and vitamin D supplementation? (2011) (11)
- Bone marrow stromal cells express two distinct splice variants of ER‐α that are regulated by estrogen (2005) (11)
- Development and Application of Mass Spectroscopy Assays for Nε-(1-Carboxymethyl)-L-Lysine and Pentosidine in Renal Failure and Diabetes. (2020) (10)
- Wnt Signaling Inhibits Osteoclast Differentiation by Activating Canonical and Noncanonical cAMP/PKA Pathways (2019) (10)
- Glycemic Control and Bone Turnover in Older Mexican Americans with Type 2 Diabetes (2018) (10)
- The trabecular effect: A population‐based longitudinal study on age and sex differences in bone mineral density and vertebral load bearing capacity (2018) (10)
- Cellular senescence and the skeleton: pathophysiology and therapeutic implications (2022) (10)
- Hip load capacity and yield load in men and women of all ages. (2020) (10)
- Pathogenesis of Osteoporosis. (2010) (10)
- Estrogen versus FSH Effects on Bone Metabolism: Evidence From Interventional Human Studies. (2020) (10)
- Orally-active, clinically-translatable senolytics restore α-Klotho in mice and humans (2022) (10)
- Statistical Parametric Mapping of HR-pQCT Images: A Tool for Population-Based Local Comparisons of Micro-Scale Bone Features (2017) (9)
- Human Immunodeficiency Virus Envelope Protein Gp120 Induces Proliferation but Not Apoptosis in Osteoblasts at Physiologic Concentrations (2011) (9)
- Personalising osteoporosis treatment for patients at high risk of fracture. (2019) (9)
- A randomized placebo-controlled trial of short-term graded transdermal estradiol in healthy gonadotropin-releasing hormone agonist-suppressed pre- and postmenopausal women: effects on serum markers of bone turnover, insulin-like growth factor-I, and osteoclastogenic mediators. (2005) (9)
- Novel anthropomorphic hip phantom corrects systemic interscanner differences in proximal femoral vBMD (2014) (8)
- CHAPTER 40 – Estrogen, Bone Homeostasis, and Osteoporosis (2008) (8)
- Validation of the Surrogate Threshold Effect for Change in Bone Mineral Density as a Surrogate Endpoint for Fracture Outcomes: The FNIH‐ASBMR SABRE Project (2021) (8)
- Expression of a potential metastasis suppressor gene (nm23) in thyroid neoplasms (1993) (8)
- Bone Microarchitecture Phenotypes Identified in Older Adults Are Associated With Different Levels of Osteoporotic Fracture Risk (2021) (8)
- The role of senolytics in osteoporosis and other skeletal pathologies (2021) (8)
- Treatment‐Related Changes in Bone Turnover and Fracture Risk Reduction in Clinical Trials of Antiresorptive Drugs: Proportion of Treatment Effect Explained (2020) (8)
- Opportunistic application of phantom-less calibration methods for fracture risk prediction using QCT/FEA (2021) (8)
- Fracture Healing in the Setting of Endocrine Diseases, Aging, and Cellular Senescence. (2022) (7)
- Posterior single-stepping thresholds are prospectively related to falls in older women (2020) (7)
- Circulating Osteogenic Progenitor Cells in Mild, Moderate, and Severe Aortic Valve Stenosis (2019) (7)
- The effects of androgens on osteoblast function in vitro. (2000) (7)
- Proceedings of the 2018 Santa Fe Bone Symposium: Advances in the Management of Osteoporosis. (2019) (7)
- Modulators of androgen and estrogen receptor activity. (2010) (7)
- Are the endocrine society's clinical practice guidelines on androgen therapy in women misguided? A commentary-response. (2007) (7)
- Estrogen Effects on Bone in the Male Skeleton (2008) (7)
- Clinical, cellular, microscopic, and ultrastructural studies of a case of fibrogenesis imperfecta ossium (2017) (7)
- Erratum: Two years of treatment with dehydroepiandrosterone does not improve insulin secretion, insulin action, or postprandial glucose turnover in elderly men or women (Diabetes (2007) 56, (753-766)) (2007) (7)
- ST-V-Net: incorporating shape prior into convolutional neural networks for proximal femur segmentation (2021) (7)
- CHAPTER 19 – Sex Steroid Effects on Bone Metabolism (2006) (6)
- Bisphosphonates and the upper gastrointestinal tract: skeletal gain without visceral pain? (2002) (6)
- Chapter 37 – Estrogens and Progestins (2002) (6)
- Estrogen and the death of osteoclasts: A fascinating story (2007) (6)
- A Deep Learning-Based Method for Automatic Segmentation of Proximal Femur from Quantitative Computed Tomography Images (2020) (6)
- Bone Marrow Adiposity in Models of Radiation‐ and Aging‐Related Bone Loss Is Dependent on Cellular Senescence (2022) (6)
- Secondary Fracture Prevention: Consensus Clinical Recommendations from a Multistakeholder Coalition. (2020) (5)
- Bone‐Targeted Replacement Therapy for Hypophosphatasia (2008) (5)
- Bone marrow stromal cells express two distinct splice variants of ER-alpha that are regulated by estrogen. (2005) (5)
- Determinants of forearm strength in postmenopausal women (2011) (5)
- Legumain is a Novel Regulator of Bone Formation and Deregulated in Postmenopausal Osteoporosis (2017) (5)
- The relationships between compensatory stepping thresholds and measures of gait, standing postural control, strength, and balance confidence in older women. (2018) (5)
- Modulation of fracture healing by the transient accumulation of senescent cells. (2021) (5)
- Osteocyte Cellular Senescence (2020) (5)
- A randomised controlled trial of low-dose aspirin for the prevention of fractures in healthy older people: protocol for the ASPREE-Fracture substudy (2015) (5)
- Corrigendum to “Characterization of circulating osteoblast lineage cells in humans” [Bone 40 (2007) 1370–1377] (2007) (5)
- Is It Time to Stop (or Pause) Vertebral Augmentation? (2019) (5)
- Role of biochemical markers in assessment of osteoporosis. (1995) (5)
- New hope for symptom management during natural and iatrogenic menopause transitions† (2017) (5)
- Detection of SARS-CoV-2 in the air from hospitals and closed rooms occupied by COVID-19 patients (2021) (5)
- Erratum to: Wnt Signaling Inhibits Osteoclast Differentiation by Activating Canonical and Noncanonical cAMP/PKA Pathways: Wnt INHIBITS OC DIFFERENTIATION BY CANONICAL/NONCANONICAL PATHWAYS (Journal of Bone and Mineral Research, (2016), 31, 1, (65-75), 10.1002/jbmr.2599) (2019) (5)
- Microfinite element modeling reveals that transient deficits in cortical bone may underlie the adolescent peak in forearm fractures (2008) (4)
- Management of Postmenopausal Osteoporosis for Primary Care (1998) (4)
- Testosterone: more is not always better. (2009) (4)
- Long-term fracture risk among women with proven endometriosis. (2006) (4)
- Chapter 41. Role of Sex Steroids in the Pathogenesis of Osteoporosis (2009) (4)
- Magic bullets to kill nasty osteoclasts. (2005) (4)
- Parathyroid Function in the Normal Aging Process (2001) (4)
- Early effects of androgen deprivation on bone and mineral homeostasis in adult men: a prospective cohort study. (2020) (4)
- A Lot of Progress, With More to Be Done: A Response to NIH Pathways to Prevention Report “Research Gaps for Long‐Term Drug Therapies for Osteoporotic Fracture Prevention” (2019) (4)
- Risk of Bone Fractures after the Diagnosis of Adrenal Adenomas: A Population-based Cohort Study. (2021) (4)
- Sex Steroids and the Pathogenesis of Osteoporosis (2018) (4)
- Bone microarchitecture, density, and geometry predict incident fracture independently of DXA BMD in older women and men: The Bone Microarchitecture International Consortium (BoMIC) (2017) (4)
- Estrogens and Bone Health (1999) (4)
- The Role of the Immune System in the Development of Osteoporosis (2011) (4)
- Estrogen deficiency and the pathogenesis of osteoporosis (2021) (3)
- Osteonecrosis of the Jaw and Atypical Femoral Fractures (2013) (3)
- Ability of Circulating Human Hematopoietic Lineage Negative Cells to Support Hematopoiesis (2015) (3)
- The microbiome adds to the complexity of parathyroid hormone action on bone. (2020) (3)
- 2016 Annual Meeting of the American Society for Bone and Mineral Research Atlanta, GA September 16–19, 2016 (2016) (3)
- Skeletal Aging. (2022) (3)
- Identification of a suitable endogenous control miRNA in bone aging and senescence (2022) (3)
- Hypercalcemia and Hyperparathyroidism (2002) (3)
- SUN-LB68 Advanced Glycation Endproducts Are Associated With Worse Bone Material Strength in Older Adults With and Without Type 2 Diabetes (2020) (3)
- Prospective randomized study of effects of unopposed estrogen replacement therapy on markers of coagulation and inflammation in postmenopausal women (2002) (3)
- A high calcium intake reverses the secondary hyperparathyroidism and increased bone resorption of elderly women (2006) (3)
- High-trauma fractures and bone mineral density. (2007) (3)
- Advancing the Science of Healthcare Service Delivery: The NHLBI Corporate Healthcare Leaders' Panel. (2018) (3)
- Insulin-like growth factor binding protein-2: a novel regulator of skeletal gender differences? (2008) (2)
- Myostatin as a mediator of sarcopenia versus homeostatic regulator of muscle mass: insights using a new mass spectrometry-based assay (2015) (2)
- Androgens and Androgenic Progestins (2001) (2)
- Effects of diabetes on osteocytes (2022) (2)
- Comparison of Vertebral and Femoral Strength Between White and Asian Adults Using Finite Element Analysis of Computed Tomography Scans (2020) (2)
- SAT-366 The Impact of Mild Autonomous Cortisol Secretion on Bone Metabolism (2019) (2)
- Osteology: Further Debate (1999) (2)
- Unitary Model of Osteoporosis Revisited (1998) (2)
- Skeletal Effects of Inducible ERα Deletion in Osteocytes in Adult Mice (2022) (2)
- SAT-176 Epidemiology of Adrenal Tumors: A Population Based Study of 1287 Patients (2020) (2)
- The classical estrogen receptor transcriptional pathway (2006) (2)
- Daily Low-Dose Aspirin and Risk of Serious Falls and Fractures in Healthy Older People: A Substudy of the ASPREE Randomized Clinical Trial. (2022) (2)
- DISORDERS OF CALCIUM METABOLISM AND BONE MINERALIZATION (2009) (1)
- In vitro and in vivo effects of zoledronate on senescence and senescence-associated secretory phenotype markers (2023) (1)
- Circulating endothelial progenitor cells co-expressing an osteogenic phenotype are increased in patients with severe calcific aortic valve stenosis (2009) (1)
- MON-219 Prevalence and Incidence of Fractures in Patients with Adrenal Adenomas: A Population-Based Study of 1003 Patients (2020) (1)
- Idiopathic osteoporosis: Is the osteoblast to blame? [4] (multiple letters) (1998) (1)
- Population-based local multi-parametric comparisons of HR-pQCT studies (2014) (1)
- Epidemiology of sarcopenia. Discussion (2000) (1)
- Virtual supersampling as post-processing step preserves the trabecular bone morphometry in human peripheral quantitative computed tomography scans (2019) (1)
- Translation to Practice: Accelerating the Cycle of Innovation to Impact (2019) (1)
- Coronary endothelial dysfunction is associated with increased risk of osteoporosis in postmenopausal women (2013) (1)
- [Senile osteoporosis]. (1988) (1)
- Reverse engineering estimation of In Vivo bone loading history (2014) (1)
- Chapter 85 – Estrogen Effects on Bone in the Male Skeleton (2002) (1)
- Multiparametric senescent cell phenotyping reveals CD24 osteolineage cells as targets of senolytic therapy in the aged murine skeleton (2023) (1)
- Does teriparatide given in combination with menopausal hormone replacement therapy improve bone mineral density? (2006) (1)
- comprehensive assessment of Osteoporosis and Bone Fragility (2016) (1)
- Bone Quality in Type 2 Diabetes Mellitus (2016) (1)
- Placebo-Controlled Fracture Trials in Osteoporosis — Comment on the Article by Stein and Ray (2010) (1)
- Validation of the OAKS prognostic model for acute kidney injury after gastrointestinal surgery (2022) (1)
- Re: "The 3.6 kb DNA fragment from the rat Col1a1 gene promoter drives the expression of genes in both osteoblast and osteoclast lineage cells" by Boban et al. (Bone 39:1302-1312, 2006). (2007) (1)
- Role of high-resolution peripheral QCT and micro-finite element modeling in assessing forearm fracture risk in postmenopausal women (2009) (1)
- Local senolysis in aged mice only partially replicates the benefits of systemic senolysis. (2023) (1)
- Guanylyl Cyclase-B Dependent Bone Formation in Mice is Associated with Youth, Increased Osteoblasts, and Decreased Osteoclasts (2022) (1)
- Skeletal considerations in the medical treatment of transgender people. (2019) (1)
- Trabecular bone deficits among Vietnamese immigrants (2011) (1)
- Getting to the bare bones of fertility (2011) (1)
- Assessing the True Impact of Recurrent Fractures on Fracture Risk (2009) (1)
- Androgens, estrogens, and bone turnover in men. Authors' reply (2003) (1)
- Determining local anisotropy in clinical CT images using a new orientation detection method: Grey Level Deviation (GLD) (2010) (1)
- Idiopathic Osteoporosis: Is the Osteoblast to Blame?—Author’s Response (1998) (1)
- Response to Wnt Signaling Pathways (2015) (1)
- Forearm fracture prediction by load/strength and in vivo microstructure assessments (2006) (1)
- Bone Density Following Long Duration Space Flight and Recovery (2010) (1)
- Diverticulitis is Associated with Increased Abdominal Visceral and Subcutaneous Fat and Muscle Mass: A Population-Based Study (2017) (1)
- Poster Presentations: Sunday, October 2, 2011 (2011) (1)
- Evaluaciones sistémicas mediante saliva: Segunda parte. Osteoporosis y empleo de la saliva para medir el recambio óseo (2006) (0)
- Establishment of normative biometric data for body composition based on computed tomography in a North American cohort. (2020) (0)
- Automated Parasite Detection System (2010) (0)
- Increasing Rates of Forearm Fractures in Children—ReplyIncreasing Rates of Forearm Fractures in Children—Reply (2003) (0)
- OSTEOLOGY: FURTHER DEBATE. AUTHORS' REPLY (1999) (0)
- 475 A Novel Means of Assessing Bone Mineral Density and Bone Strength in Patients With Inflammatory Bowel Disease Undergoing CT Enterography (2013) (0)
- Osteoporosis in the USA: prevention and unmet needs. (2022) (0)
- Priscilla Chen 1944–2013 (2014) (0)
- The Role of Androgens and Estrogens in the Male Skeleton (2004) (0)
- Seeding Open Innovation Drug Discovery and Translational Collaborations to Leverage Government Funding: A Case Study of Strategic Partnership between Sanford‐Burnham and Mayo Clinic (2014) (0)
- Senescent cells, senolytics and tissue repair: the devil may be in the dosing (2023) (0)
- Identification of osteoclast-osteoblast coupling factors in humans reveals links between bone and energy metabolism (2020) (0)
- Increasing Rates of Forearm Fractures in Children--Reply (2003) (0)
- OSTEOCALCIN POSITIVE CD133p/CD34-/KDRp PROGENITOR CELLS ARE ASSOCIATED WITH POOR GLYCEMIC CONTROL (2012) (0)
- RETENTION OF OSTEOGENIC CD14–MONOCYTES WITHIN THE CORONARY CIRCULATION CORRELATES WITH CORONARY CALCIFICATION (2013) (0)
- Benefits and risks of bisphosphonate therapy for osteoporosis: Editorial comment (2013) (0)
- Plasma sclerostin is associated with visceral adipose tissue but not subcutaneous adipose tissue in men and women in the Framingham Study (2020) (0)
- Early effects of androgen deprivation on bone and mineral homeostasis: A prospective cohort study (2020) (0)
- Abstract 721: Expression of Osteocalcin by Circulating Endothelial Progenitor Cells Predicts Endothelial Dysfunction or Structural Coronary Artery Disease (2007) (0)
- SUN-381 Cortical Porosity Is Associated with Peripheral Small Vessel Disease in Adult Patients with Type 2 Diabetes (2020) (0)
- Identification of novel factors involved in the coupling of bone resorption and bone formation in humans reveals RANKL/DPP4 as a new link between bone remodeling and energy metabolism (2019) (0)
- Abstract 5564: Circulating Endothelial Progenitor Cells Co-Expressing an Osteobastic Phenotype Are Increased in Patients With Severe Calcific Aortic Valve Stenosis (2009) (0)
- Parathyroid Hormone in the Pathophysiology of Osteoporosis (2015) (0)
- Estrogens and progestins (2020) (0)
- MicroRNA ‐ 19a ‐ 3p Decreases with Age in Mice and Humans and Inhibits Osteoblast Senescence (2023) (0)
- Author response for "Validation of the Surrogate Threshold Effect for Change in BMD as a Surrogate Endpoint for Fracture Outcomes: the FNIH‐ASBMR SABRE Project" (2021) (0)
- Biology and Clinical Aspects of Estrogen Action on Bone (2019) (0)
- Effects of Glycemic Control on Bone Turnover in Older Mexican Americans with Type 2 Diabetes: Data from the Cameron County Hispanic Cohort in Texas (2016) (0)
- Non-invasive Quantification of Changes in Bone Micro-architecture and Strength: Three Year Follow-up at the Distal Radius (2011) (0)
- Sex-and Age-Related Differences in BoneMicroarchitecture in Men Relative toWomen Assessed by High-Resolution Peripheral Quantitative Computed Tomography (2014) (0)
- QCT/FEA Models of Proximal Femur Stiffness and Ultimate Load Using Experimentally Matched Boundary (2011) (0)
- Increasing rates of forearm fractures in children. Authors' reply (2003) (0)
- Decision letter: Irisin directly stimulates osteoclastogenesis and bone resorption in vitro and in vivo (2020) (0)
- Su1161 Novel CT-Derived Bone Assessments in Non-Responsive Celiac Disease Patients (2017) (0)
- Insulin-like growth factor (IGF)-II/IGF-binding proteins in constitutionally tall children. (2003) (0)
- Statistical Parametric Mapping of HR-pQCT Images: A Tool for Population-Based Local Comparisons of Micro-Scale Bone Features (2016) (0)
- List of contributors (2021) (0)
- Increasing Rates of Forearm Fractures in Children [4] (multiple letters) (2003) (0)
- Osteocalcin Levels in Older Mexican Americans with Type 2 Diabetes: Data from the Cameron County Hispanic Cohort in Texas (2016) (0)
- Osteoporosis and Men’s Health (Final 4/07/05) (2005) (0)
- Does Short Duration Space Flight have a Negative Effect on Bone Density (2011) (0)
- Mechanisms of age-related bone loss (ECTS Excellence in Research Lecture) (2012) (0)
- Erratum: Role of circulating osteogenic progenitor cells in calcific aortic stenosis (Journal of the American College of Cardiology (2012) 60 (194553)) (2012) (0)
- Osteoporosis: Guidelines for Management: P-63. (1996) (0)
- Precision of two HR-PQCT scanners for the longitudinal evaluation of human bone microarchitecture in vivo (2011) (0)
- Impaired Muscle Strength and Performance in Patients With Mild Autonomous Cortisol Secretion (2021) (0)
- FRI0572 Identifying women and men at high fracture risk by leveraging the electronic medical records to estimate frax treatment thresholds (2017) (0)
- CLINICAL PRACTICE GUIDELINE Androgen Therapy in Women: An Endocrine Society Clinical Practice Guideline (2006) (0)
- Deficits in cortical bone may cause increased incidence of forearm fractures during adolescence (2009) (0)
- Impaired Cognitive Performance in Patients With Mild Autonomous Cortisol Secretion (2021) (0)
- Review for "Circulating Osteocalcin‐Positive Cells as a Novel Diagnostic Biomarker for Bone Metastasis in Breast Cancer Patients" (2020) (0)
- Roles of cellular senescence in driving bone marrow adiposity in radiation- and aging-associated bone loss (2021) (0)
- Intestinal Wall Remodeling on CT Enterography May Not Predict Improved Bone Health: 1720 (2013) (0)
- Corrigendum to “Letter to the Editor” [Bone 38 (2006) 289] (2011) (0)
- Abstract 14624: Delivery of Osteocalcin (OCN+) Expressing Myeloid Cells is Sufficient to Generate Vascular Calcification (2012) (0)
- Response to Stoecker et al (2017) (0)
- Corrigendum to "Circulating osteogenic cells: Characterization and relationship to rates of bone loss in postmenopausal women" [Bone 47 (2010) 83-92] (2011) (0)
- Urinary Steroid Metabolome Signature is Associated With Cognitive Function in Older Adults (2021) (0)
- Urinary Steroid Metabolome Signature Is Associated With Pre-Frailty and Frailty Phenotype in Older Adults (2021) (0)
- CURRENT STATE OF SCIENCE ON DRUG THERAPIES FOR OSTEOPOROTIC FRACTURE PREVENTION (2019) (0)
- Senolytics improve physical function and increase lifespan in old age (2018) (0)
- New hope for symptom management during natural and iatrogenic menopause transitions† (2017) (0)
- Subspecialty Clinics: Endocrinology, Metabolism, and Nutrition Update on Primary Osteoporosis (1997) (0)
- OSTEOCALCIN POSITIVE CD133p/CD34-/KDRp PROGENITOR CELLS AS MARKERS OF CORONARY ARTERY DISEASE AND PROGNOSIS (2012) (0)
- Comparative Analysis of Osteoclast Lineage Cre-Drivers and Identification of Novel Osteoclast Lineage Selective Genes (2014) (0)
- Abstract #121 Bone Metabolism in Primary Hyperaldosteronism: a Pilot Study (2019) (0)
- 9 Postmenopausal Osteoporosis (1999) (0)
- A Fracture Risk Assessment Tool for High Resolution Peripheral Quantitative Computed Tomography. (2023) (0)
- Tell Our Patients about Calcium and Vitamin D Supplementation ? (2010) (0)
- Author response for "Targeted reduction of senescent cell burden alleviates focal radiotherapy‐related bone loss" (2020) (0)
- Global and Spatial Compartmental Interrelationships of Bone Density, Microstructure, Geometry and Biomechanics in the Distal Radius in a Colles’ Fracture Study Using HR-pQCT (2021) (0)
- The Role of Wnt‐10b in Osteoblast Development (2010) (0)
- Three-Year Follow-up on Changes in Bone Micro-architecture and Bone Strength at the Distal Radius (2012) (0)
- GDF15, a potential marker of cell senescence, and increased risk of hip fracture (2022) (0)
- BONE DISEASE FROM BENCH TO BEDSIDE Advanced Glycation Endproducts Are Associated With Worse Bone Material Strength in Older Adults With and Without Type 2 Diabetes (2020) (0)
- Ultradistal Radius in Women and Men Hormonal and Biochemical Determinants of Trabecular Microstructure at the (2005) (0)
- Reference Intervals for Bone Impact Microindentation in Healthy Adults: A Multi-Centre International Study (2023) (0)
- Abstract 217: Coronary Endothelial Dysfunction is Associated With Increased Risk of Osteoporosis (2013) (0)
- List of Contributors (2020) (0)
- Author response: Modulation of fracture healing by the transient accumulation of senescent cells (2021) (0)
- This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the authors' clinical recommendations. Osteopenia (2007) (0)
- 全年齢の男性と女性における股関節負荷容量と収量負荷【JST・京大機械翻訳】 (2020) (0)
- Osteoporosis y la salud masculina (Final 4/7/05) (2005) (0)
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What Schools Are Affiliated With Sundeep Khosla?
Sundeep Khosla is affiliated with the following schools:
