Susan Baker
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American virologist
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Virology
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Microbiology
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Biology
Susan Baker 's Degrees
- Bachelors Biology University of California, Berkeley
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Why Is Susan Baker Influential?
(Suggest an Edit or Addition)According to Wikipedia, Susan C. Baker is an American molecular virologist and professor at Loyola University Chicago, Illinois. She teaches microbiology and immunology within the Loyola Medicine Health System. She received her Ph.D. from Vanderbilt University. Currently, she has 80 publications, dating back to 1987, within each of the following disciplines: microbiology, infectious disease, and infectious disease control to name a few. A list of her publications can be found here.
Susan Baker 's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2 (2020) (5195)
- Severe acute respiratory syndrome-related coronavirus: The species and its viruses – a statement of the Coronavirus Study Group (2020) (1373)
- Commentary: Middle East Respiratory Syndrome Coronavirus (MERS-CoV): Announcement of the Coronavirus Study Group (2013) (1101)
- Ribose 2′-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5 (2011) (663)
- The Papain-Like Protease of Severe Acute Respiratory Syndrome Coronavirus Has Deubiquitinating Activity (2005) (476)
- RNA Replication of Mouse Hepatitis Virus Takes Place at Double-Membrane Vesicles (2002) (434)
- Identification of Severe Acute Respiratory Syndrome Coronavirus Replicase Products and Characterization of Papain-Like Protease Activity (2004) (406)
- A noncovalent class of papain-like protease/deubiquitinase inhibitors blocks SARS virus replication (2008) (397)
- Severe acute respiratory syndrome coronavirus papain-like protease: structure of a viral deubiquitinating enzyme. (2006) (374)
- Regulation of IRF-3-dependent Innate Immunity by the Papain-like Protease Domain of the Severe Acute Respiratory Syndrome Coronavirus (2007) (349)
- Deubiquitinating and Interferon Antagonism Activities of Coronavirus Papain-Like Proteases (2010) (287)
- Coronavirus nonstructural protein 15 mediates evasion of dsRNA sensors and limits apoptosis in macrophages (2017) (265)
- Three Linked Vasculopathic Processes Characterize Kawasaki Disease: A Light and Transmission Electron Microscopic Study (2012) (260)
- Coronavirus Papain-like Proteases Negatively Regulate Antiviral Innate Immune Response through Disruption of STING-Mediated Signaling (2012) (238)
- Severe acute respiratory syndrome-related coronavirus: The species and its viruses – a statement of the Coronavirus Study Group (2020) (218)
- MERS-CoV papain-like protease has deISGylating and deubiquitinating activities (2013) (198)
- Coronavirus endoribonuclease targets viral polyuridine sequences to evade activating host sensors (2020) (197)
- IgA plasma cell infiltration of proximal respiratory tract, pancreas, kidney, and coronary artery in acute Kawasaki disease. (2000) (193)
- Oligoclonal IgA Response in the Vascular Wall in Acute Kawasaki Disease1 (2001) (189)
- Tubulin: a factor necessary for the synthesis of both Sendai virus and vesicular stomatitis virus RNAs. (1986) (184)
- Human hepatitis delta antigen is a nuclear phosphoprotein with RNA-binding activity (1988) (181)
- Structural Basis for the Ubiquitin-Linkage Specificity and deISGylating Activity of SARS-CoV Papain-Like Protease (2014) (169)
- IgA plasma cells in vascular tissue of patients with Kawasaki syndrome. (1997) (169)
- X-ray Structural and Biological Evaluation of a Series of Potent and Highly Selective Inhibitors of Human Coronavirus Papain-like Proteases (2014) (168)
- Discovery, synthesis, and structure-based optimization of a series of N-(tert-butyl)-2-(N-arylamido)-2-(pyridin-3-yl) acetamides (ML188) as potent noncovalent small molecule inhibitors of the severe acute respiratory syndrome coronavirus (SARS-CoV) 3CL protease. (2013) (157)
- Human Monoclonal Antibodies against Highly Conserved HR1 and HR2 Domains of the SARS-CoV Spike Protein Are More Broadly Neutralizing (2012) (156)
- Host cell proteins required for measles virus reproduction. (1990) (152)
- Nidovirus papain-like proteases: Multifunctional enzymes with protease, deubiquitinating and deISGylating activities (2014) (151)
- Evaluating the 3C-like protease activity of SARS-Coronavirus: Recommendations for standardized assays for drug discovery (2007) (150)
- Searching for the cause of Kawasaki disease — cytoplasmic inclusion bodies provide new insight (2008) (137)
- The papain-like protease of porcine epidemic diarrhea virus negatively regulates type I interferon pathway by acting as a viral deubiquitinase. (2013) (136)
- Assessing Activity and Inhibition of Middle East Respiratory Syndrome Coronavirus Papain-Like and 3C-Like Proteases Using Luciferase-Based Biosensors (2013) (130)
- Severe acute respiratory syndrome coronavirus papain-like novel protease inhibitors: design, synthesis, protein-ligand X-ray structure and biological evaluation. (2010) (123)
- Masitinib is a broad coronavirus 3CL inhibitor that blocks replication of SARS-CoV-2 (2021) (117)
- Design and synthesis of peptidomimetic severe acute respiratory syndrome chymotrypsin-like protease inhibitors. (2005) (116)
- Characterization of hepatitis delta antigen: specific binding to hepatitis delta virus RNA (1990) (114)
- Identification of the catalytic sites of a papain-like cysteine proteinase of murine coronavirus (1993) (112)
- Ultrastructural, immunofluorescence, and RNA evidence support the hypothesis of a "new" virus associated with Kawasaki disease. (2011) (111)
- Colocalization and Membrane Association of Murine Hepatitis Virus Gene 1 Products and De Novo-Synthesized Viral RNA in Infected Cells (1999) (111)
- Catalytic Function and Substrate Specificity of the Papain-Like Protease Domain of nsp3 from the Middle East Respiratory Syndrome Coronavirus (2014) (109)
- Proteolytic Processing and Deubiquitinating Activity of Papain-Like Proteases of Human Coronavirus NL63 (2007) (108)
- Structure-based design, synthesis, and biological evaluation of a series of novel and reversible inhibitors for the severe acute respiratory syndrome-coronavirus papain-like protease. (2009) (106)
- Design, synthesis and antiviral efficacy of a series of potent chloropyridyl ester-derived SARS-CoV 3CLpro inhibitors (2008) (106)
- Identification of a domain required for autoproteolytic cleavage of murine coronavirus gene A polyprotein (1989) (105)
- An “Old” protein with a new story: Coronavirus endoribonuclease is important for evading host antiviral defenses (2018) (101)
- Coronavirus Infection Modulates the Unfolded Protein Response and Mediates Sustained Translational Repression (2008) (101)
- Processing of the Coronavirus MHV-JHM Polymerase Polyprotein: Identification of Precursors and Proteolytic Products Spanning 400 Kilodaltons of ORF1a☆ (1998) (96)
- Detection of antigen in bronchial epithelium and macrophages in acute Kawasaki disease by use of synthetic antibody. (2004) (94)
- Structure-based design, synthesis, and biological evaluation of peptidomimetic SARS-CoV 3CLpro inhibitors (2007) (90)
- Primary structure and translation of a defective interfering rna of murine coronavirus (1988) (89)
- Membrane topology of murine coronavirus replicase nonstructural protein 3 (2007) (89)
- Evolution of Mouse Hepatitis Virus (MHV) during Chronic Infection: Quasispecies Nature of the Persisting MHV RNA (1995) (88)
- Mutation in murine coronavirus replication protein nsp4 alters assembly of double membrane vesicles (2008) (87)
- Coronavirus Endoribonuclease Activity in Porcine Epidemic Diarrhea Virus Suppresses Type I and Type III Interferon Responses (2019) (84)
- Cytoplasmic Inclusion Bodies Are Detected by Synthetic Antibody in Ciliated Bronchial Epithelium during Acute Kawasaki Disease (2005) (80)
- Human Coronavirus NL63 Is Not Detected in the Respiratory Tracts of Children with Acute Kawasaki Disease (2005) (79)
- RNA-Containing Cytoplasmic Inclusion Bodies in Ciliated Bronchial Epithelium Months to Years after Acute Kawasaki Disease (2008) (77)
- Evolution of mouse hepatitis virus: detection and characterization of spike deletion variants during persistent infection (1997) (77)
- Identification of Mouse Hepatitis Virus Papain-Like Proteinase 2 Activity (2000) (75)
- Coronaviruses Resistant to a 3C-Like Protease Inhibitor Are Attenuated for Replication and Pathogenesis, Revealing a Low Genetic Barrier but High Fitness Cost of Resistance (2014) (71)
- Cell-based antiviral screening against coronaviruses: Developing virus-specific and broad-spectrum inhibitors (2013) (65)
- Sequence and translation of the murine coronavirus 5'-end genomic RNA reveals the N-terminal structure of the putative RNA polymerase (1987) (63)
- Determinants of the p28 Cleavage Site Recognized by the First Papain-like Cysteine Proteinase of Murine Coronavirus (1994) (61)
- The papain-like protease determines a virulence trait that varies among members of the SARS-coronavirus species (2018) (59)
- An in vitro system for the leader-primed transcription of coronavirus mRNAs. (1990) (58)
- Generation of coronavirus spike deletion variants by high-frequency recombination at regions of predicted RNA secondary structure (1997) (56)
- The transcriptional profile of coronary arteritis in Kawasaki disease (2015) (55)
- Cloning the Arterial IgA Antibody Response during Acute Kawasaki Disease1 (2005) (51)
- Detection of Nonstructural Protein 6 in Murine Coronavirus-Infected Cells and Analysis of the Transmembrane Topology by Using Bioinformatics and Molecular Approaches (2009) (49)
- Murine Coronavirus Ubiquitin-Like Domain Is Important for Papain-Like Protease Stability and Viral Pathogenesis (2015) (47)
- Human airway epithelial cell culture to identify new respiratory viruses: Coronavirus NL63 as a model (2008) (44)
- Hemagglutinin-esterase-specific monoclonal antibodies alter the neuropathogenicity of mouse hepatitis virus (1992) (40)
- Progress in Anti-SARS Coronavirus Chemistry, Biology and Chemotherapy (2006) (39)
- Encapsidation of Sendai virus genome RNAs by purified NP protein during in vitro replication (1988) (39)
- Deubiquitinating Activity of the SARS-CoV Papain-Like Protease (2006) (39)
- Drug repurposing screen identifies masitinib as a 3CLpro inhibitor that blocks replication of SARS-CoV-2 in vitro (2020) (38)
- X-ray Structural and Functional Studies of the Three Tandemly Linked Domains of Non-structural Protein 3 (nsp3) from Murine Hepatitis Virus Reveal Conserved Functions* (2015) (38)
- X-ray Structure and Enzymatic Activity Profile of a Core Papain-like Protease of MERS Coronavirus with utility for structure-based drug design (2017) (35)
- Morphogenesis of Coronavirus HCoV-NL63 in Cell Culture: A Transmission Electron Microscopic Study. (2009) (35)
- Identification of the Murine Coronavirus MP1 Cleavage Site Recognized by Papain-Like Proteinase 2 (2003) (34)
- Persistence of viral RNA in the central nervous system of mice inoculated with MHV-4. (1993) (31)
- SARS-CoV-2 Disrupts Proximal Elements in the JAK-STAT Pathway (2021) (31)
- A Protein Epitope Targeted by the Antibody Response to Kawasaki Disease. (2020) (30)
- Coronavirus Endoribonuclease and Deubiquitinating Interferon Antagonists Differentially Modulate the Host Response during Replication in Macrophages (2020) (28)
- Analysis of Coronavirus Temperature-Sensitive Mutants Reveals an Interplay between the Macrodomain and Papain-Like Protease Impacting Replication and Pathogenesis (2019) (27)
- Competitive Fitness in Coronaviruses Is Not Correlated with Size or Number of Double-Membrane Vesicles under Reduced-Temperature Growth Conditions (2014) (26)
- A Study of Cardiovascular miRNA Biomarkers for Kawasaki Disease (2014) (26)
- A New Cistron in the Murine Hepatitis Virus Replicase Gene (2010) (24)
- Quasispecies development by high frequency RNA recombination during MHV persistence. (1998) (22)
- Structure-Guided Mutagenesis Alters Deubiquitinating Activity and Attenuates Pathogenesis of a Murine Coronavirus (2019) (21)
- Human Coronavirus-NL63 Infection is not Associated with Acute Kawasaki Disease (2006) (19)
- Mutations associated with viral sequences isolated from mice persistently infected with MHV-JHM. (1995) (19)
- Detecting SARS-CoV-2 3CLpro expression and activity using a polyclonal antiserum and a luciferase-based biosensor (2021) (19)
- Identification of the polymerase polyprotein products p72 and p65 of the murine coronavirus MHV-JHM (1996) (19)
- A Chimeric Virus-Mouse Model System for Evaluating the Function and Inhibition of Papain-Like Proteases of Emerging Coronaviruses (2014) (18)
- SARS-CoV-2 desensitizes host cells to interferon through inhibition of the JAK-STAT pathway (2020) (17)
- Drosophila S virus, a hereditary reolike virus, probable agent of the morphological S character in Drosophila simulans (1988) (17)
- Inactivating Three Interferon Antagonists Attenuates Pathogenesis of an Enteric Coronavirus (2020) (16)
- Allograft Inflammatory Factor-1 Links T-Cell Activation, Interferon Response, and Macrophage Activation in Chronic Kawasaki Disease Arteritis (2017) (16)
- Coronaviruses: from common colds to severe acute respiratory syndrome. (2004) (16)
- Characterizing replication kinetics and plaque production of type I feline infectious peritonitis virus in three feline cell lines (2018) (15)
- Integrins alpha4 and alpha M, collagen1A1, and matrix metalloproteinase 7 are upregulated in acute Kawasaki disease vasculopathy (2012) (15)
- Coronaviruses: Molecular Biology (2008) (15)
- Breakthrough Infections with Multiple Lineages of SARS-CoV-2 Variants Reveals Continued Risk of Severe Disease in Immunosuppressed Patients (2021) (12)
- Coronavirus infection induces progressive restructuring of the endoplasmic reticulum involving the formation and degradation of double membrane vesicles (2020) (11)
- Murine coronavirus gene 1 polyprotein contains an autoproteolytic activity. (1990) (11)
- Spike and nsp6 are key determinants of SARS-CoV-2 Omicron BA.1 attenuation (2023) (11)
- Periostin is Upregulated in Coronary Arteriopathy in Kawasaki Disease and is a Potential Diagnostic Biomarker (2014) (10)
- Catalytic Function and Substrate Specificity of the PLpro Domain of nsp 3 from 1 the Middle East Respiratory Syndrome Coronavirus ( MERS-CoV ) 2 3 (2014) (9)
- CD84 is markedly up‐regulated in Kawasaki disease arteriopathy (2014) (9)
- 1 REGULATION OF IRF-3 DEPENDENT INNATE IMMUNITY BY THE PAPAIN-LIKE PROTEASE DOMAIN OF THE SARS CORONAVIRUS (2007) (9)
- Processing of the replicase of murine coronavirus: papain-like proteinase 2 (PLP2) acts to generate p150 and p44. (2001) (8)
- Murine hepatitis virus nsp4 N258T mutants are not temperature-sensitive (2012) (8)
- Generating and evaluating type I interferon receptor-deficient and feline TMPRSS2-expressing cells for propagating serotype I feline infectious peritonitis virus (2019) (7)
- Mouse Hepatitis Virus Infection Activates the IRE1/XBP1 Pathway of the Unfolded Protein Response (2006) (6)
- Renilla Luciferase as a Reporter to Assess SARS-CoV mRNA Transcription Regulation and Efficacy of ANTI-SARS-CoV Agents (2006) (6)
- Role of spike in the pathogenic and antigenic behavior of SARS-CoV-2 BA.1 Omicron (2022) (5)
- Cell Biology of Nidovirus Replication Complexes (2008) (5)
- Coronavirus Interferon Antagonists Differentially Modulate the Host Response during Replication in Macrophages (2019) (4)
- Maturation of the polymerase polyprotein of the coronavirus MHV strain JHM involves a cascade of proteolytic processing events. (1998) (3)
- Development and utilization of an infectious clone for porcine deltacoronavirus strain USA/IL/2014/026 (2020) (3)
- Sequencing during Times of Change: Evaluating SARS-CoV-2 Clinical Samples during the Transition from the Delta to Omicron Wave (2022) (2)
- Comparison of replicase localization in different types of mouse hepatitis virus (MHV)-infected cells. (2001) (2)
- Altered proteolytic processing of the polymerase polyprotein in RNA(-) temperature sensitive mutants of murine coronavirus. (1993) (2)
- Use of Centers for Disease Control and Prevention Gravid Trap in Catch Basins: Proof-Of-Concept Trials (2015) (2)
- Coronaviruses as a cause of vascular disease: a comparative medicine approach (2020) (2)
- Local production of IgA in vascular tissue in fatal Kawasaki Syndrome. • 761 (1997) (2)
- Proteolytic processing of the MHV polymerase polyprotein. Identification of the P28 cleavage site and the adjacent protein, P65. (1995) (2)
- Antibody Response to SARS-CoV-2 Infection and Vaccination in COVID-19-naïve and Experienced Individuals (2022) (1)
- Development of a Mouse Model of Human Coronavirus NL63 (HCoV-NL63) Infection (2021) (1)
- Developing Bioinformatic Resources for Coronaviruses (2006) (1)
- X-ray structural analysis of SARS coronavirus 3CL proteinase in complex with designed anti-viral inhibitors (2006) (1)
- Proteolytic Processing of the MHV Polymerase Polyprotein (1995) (1)
- Clonally related IgA sequences in a vascular cDNA library from a patient with fatal acute Kawasaki Syndrome(KS) † 905 (1998) (1)
- Coronavirus Papain-like Peptidases (2012) (1)
- A highly sensitive cell-based luciferase assay for high-throughput automated screening of SARS-CoV-2 nsp5/3CLpro inhibitors (2022) (1)
- Exploiting DNA immunization to generate polyclonal antisera to coronavirus replicase proteins. (2001) (1)
- Wall in Acute Kawasaki Disease Oligoclonal IgA Response in the Vascular (2000) (0)
- Coronaviruses: Molecular Biology (Coronaviridae) (2021) (0)
- Identification of Kawasaki Disease (KD) Antigens Using Synthetic KD Antibodies (2003) (0)
- Editorial Board (2016) (0)
- 1876. A Hepacivirus-Like Protein Is Targeted by the Antibody Response to Kawasaki Disease (KD) (2019) (0)
- X-ray structural of three tandemly linked domains of nsp3 from murine hepatitis virus at 2.60 Angstroms resolution (2015) (0)
- Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) 3CL Protease in Complex with N-[(1R)-2-(tert-butylamino)-2-oxo-1-(pyridin-3-yl)ethyl]-N-(4-tert-butylphenyl)furan-2-carboxamide inhibitor. (2013) (0)
- Cell culture systems for isolation of SARS-CoV-2 clinical isolates and generation of recombinant virus (2023) (0)
- HCoV-NL63 and HCoV-HKU1 Rates of Infection in Chicago: Winter 2011 (2013) (0)
- Abstract 13308: The Transcriptome of Kawasaki Disease Arteritis Reveals Activation of T Lymphocyte and Natural Killer Cell Function, Antigen Presentation, Immunoglobulin Production, and Interferon Response (2014) (0)
- Abstract O.20: Deep RNA Sequencing Reveals a Transcriptional Profile of Cytotoxic T Lymphocyte Activation, Antigen Presentation, Immunoglobulin Production, and Type I Interferon Response in Kawasaki Disease Arteritis (2015) (0)
- Kawasaki Disease Vasculopathy, Process 3: Luminal Myofibroblastic Proliferation (LMP). (2012) (0)
- Kawasaki Disease Vasculopathy, Process 1, Necrotizing Arteritis (NA). (2012) (0)
- 1 Ribose 2 '-O-methylation provides a molecular signature for MDA 5-dependent distinction 1 of self and non-self mRNA 2 3 (2018) (0)
- Editorial Board (2016) (0)
- Editorial overview: 2022 “Virus–Host Interaction” section of Current Opinion in Virology (2022) (0)
- Abstract O.40: Persistent Subacute/Chronic Coronary Arteritis in Kawasaki Disease (KD): Histologic, RNA and Protein Evidence (2015) (0)
- Introduction to Virology special issue featuring nidovirus research (2018) (0)
- Papain-Like Proteinase 2 Activity Identification of Mouse Hepatitis Virus (2000) (0)
- during Acute Kawasaki Disease Cloning the Arterial IgA Antibody Response (0)
- Coronaviruses: Molecular Biology☆ (2014) (0)
- MURINE CORONA VIRUS GENE 1 POL YPROTEIN CONTAINS AN AUTOPROTEOL YTIC ACTIVITY SUMMARY (2012) (0)
- Kinetic and crystallographic analyses of SARS coronavirus 3CLpro inhibitors (2005) (0)
- The transcriptional profile of coronary arteritis in Kawasaki disease (2015) (0)
- The urothelial transcriptomic response to interferon gamma predicts T1 recurrence-free and basal/squamous muscle-invasive bladder cancer survival and better targeted strategies for immune checkpoint blocking. (2022) (0)
- Analysis of Plasmablasts from Children with Kawasaki Disease Reveals Evidence of a Convergent Antibody Response to a Specific Protein Epitope. (2023) (0)
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