Susan Kaech

Q: What Schools Are Affiliated With Susan Kaech

Susan Kaech is affiliated with the following schools: Yale University, Stanford University, University of Washington, University of Cambridge

Susan Kaech's AcademicInfluence.com Rankings

Susan Kaech

Biology

#9930

World Rank

#13198

Historical Rank

Immunology

#606

World Rank

#626

Historical Rank

biology Degrees

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Biology

Susan Kaech's Degrees

Bachelors Biological Sciences Stanford University

Why Is Susan Kaech Influential?

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According to Wikipedia, Susan Kaech is an American immunologist. Kaech is a professor and director of the NOMIS Center for Immunobiology and Microbial Pathogenesis at the Salk Institute for Biological Sciences. She holds the NOMIS Foundation Chair. Her research focuses on the formation of memory T cells, T cell metabolism, and cancer immunotherapy.

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Susan Kaech's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Lineage relationship and protective immunity of memory CD8 T cell subsets (2003) (2030)
Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells (2003) (1957)
Molecular signature of CD8+ T cell exhaustion during chronic viral infection. (2007) (1779)
Inflammation directs memory precursor and short-lived effector CD8(+) T cell fates via the graded expression of T-bet transcription factor. (2007) (1705)
Memory CD8+ T cell differentiation: initial antigen encounter triggers a developmental program in naïve cells (2001) (1457)
Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin (2005) (1210)
Transcriptional control of effector and memory CD8+ T cell differentiation (2012) (1207)
Mitochondrial DNA Stress Primes the Antiviral Innate Immune Response (2014) (1096)
Molecular and Functional Profiling of Memory CD8 T Cell Differentiation (2002) (1036)
Effector and memory T-cell differentiation: implications for vaccine development. Nat Rev Immunol. (2002) (977)
Vaccines: Effector and memory T-cell differentiation: implications for vaccine development (2002) (939)
Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses (2015) (930)
Metabolic Instruction of Immunity (2017) (735)
Estimating the Precursor Frequency of Naive Antigen-specific CD8 T Cells (2002) (681)
Heterologous immunity provides a potent barrier to transplantation tolerance. (2003) (629)
Heterogeneity and cell-fate decisions in effector and memory CD8+ T cell differentiation during viral infection. (2007) (615)
Transcriptional repressor Blimp-1 promotes CD8(+) T cell terminal differentiation and represses the acquisition of central memory T cell properties. (2009) (570)
Antigen-independent memory CD8 T cells do not develop during chronic viral infection. (2004) (558)
Hepatic Acetyl CoA Links Adipose Tissue Inflammation to Hepatic Insulin Resistance and Type 2 Diabetes (2015) (521)
Therapeutic use of IL-2 to enhance antiviral T-cell responses in vivo (2003) (421)
Impaired HLA Class I Antigen Processing and Presentation as a Mechanism of Acquired Resistance to Immune Checkpoint Inhibitors in Lung Cancer. (2017) (397)
The LIN-2/LIN-7/LIN-10 Complex Mediates Basolateral Membrane Localization of the C. elegans EGF Receptor LET-23 in Vulval Epithelial Cells (1998) (364)
An interleukin-21-interleukin-10-STAT3 pathway is critical for functional maturation of memory CD8+ T cells. (2011) (358)
The multifaceted role of CD4+ T cells in CD8+ T cell memory (2016) (354)
CD4+ T cell help guides formation of CD103+ lung-resident memory CD8+ T cells during influenza viral infection. (2014) (302)
Natural killer cell activation enhances immune pathology and promotes chronic infection by limiting CD8+ T-cell immunity (2011) (295)
In Vivo Regulation of Bcl6 and T Follicular Helper Cell Development (2010) (283)
LET-23 Receptor Localization by the Cell Junction Protein LIN-7 during C. elegans Vulval Induction (1996) (276)
The transcription factor FoxO1 sustains expression of the inhibitory receptor PD-1 and survival of antiviral CD8(+) T cells during chronic infection. (2014) (270)
Differential expression of Ly6C and T-bet distinguish effector and memory Th1 CD4(+) cell properties during viral infection. (2011) (269)
Loss of CD127 Expression Defines an Expansion of Effector CD8+ T Cells in HIV-Infected Individuals1 (2005) (264)
Generation of effector CD8+ T cells and their conversion to memory T cells (2010) (259)
Effector CD8 T Cell Development: A Balancing Act between Memory Cell Potential and Terminal Differentiation1 (2008) (245)
IL-7-Induced Glycerol Transport and TAG Synthesis Promotes Memory CD8+ T Cell Longevity (2015) (242)
The microRNA miR-181 is a critical cellular metabolic rheostat essential for NKT cell ontogenesis and lymphocyte development and homeostasis. (2013) (242)
Role of sustained antigen release from nanoparticle vaccines in shaping the T cell memory phenotype. (2012) (240)
KLRG1+ Effector CD8+ T Cells Lose KLRG1, Differentiate into All Memory T Cell Lineages, and Convey Enhanced Protective Immunity (2018) (233)
The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells. (2015) (225)
Expression of IL-7 receptor α is necessary but not sufficient for the formation of memory CD8 T cells during viral infection (2007) (218)
The role of programming in memory T-cell development. (2004) (214)
Lung airway-surveilling CXCR3(hi) memory CD8(+) T cells are critical for protection against influenza A virus. (2013) (200)
Transcription factor STAT3 and type I interferons are corepressive insulators for differentiation of follicular helper and T helper 1 cells. (2014) (198)
Differential effects of STAT5 and PI3K/AKT signaling on effector and memory CD8 T-cell survival (2010) (196)
Identification of an Evolutionarily Conserved Heterotrimeric Protein Complex Involved in Protein Targeting* (1998) (192)
The transcription factors ZEB2 and T-bet cooperate to program cytotoxic T cell terminal differentiation in response to LCMV viral infection (2015) (182)
Models of CD8+ responses: 1. What is the antigen-independent proliferation program. (2003) (168)
Requirement of B Cells for Generating CD4+ T Cell Memory1 (2009) (167)
Production of IL-10 by CD4+ regulatory T cells during the resolution of infection promotes the maturation of memory CD8+ T cells (2015) (160)
Polycomb Repressive Complex 2‐Mediated Chromatin Repression Guides Effector CD8+ T Cell Terminal Differentiation and Loss of Multipotency (2017) (155)
PDZ‐mediated interactions retain the epithelial GABA transporter on the basolateral surface of polarized epithelial cells (1999) (147)
Proteomics of Melanoma Response to Immunotherapy Reveals Mitochondrial Dependence (2019) (144)
CD8 T Cells Remember with a Little Help (2003) (142)
Uptake of oxidized lipids by the scavenger receptor CD36 promotes lipid peroxidation and dysfunction in CD8+ T cells in tumors. (2021) (142)
A molecular threshold for effector CD8+ T cell differentiation controlled by transcription factors Blimp-1 and T-bet (2016) (138)
A Specific Role for B Cells in the Generation of CD8 T Cell Memory by Recombinant Listeria monocytogenes 1 (2003) (128)
TCR Signal Transduction in Antigen-Specific Memory CD8 T Cells1 (2003) (127)
Effects of Signal 3 during CD8 T cell priming: Bystander production of IL-12 enhances effector T cell expansion but promotes terminal differentiation. (2009) (126)
Prostaglandin E2 and programmed cell death 1 signaling coordinately impair CTL function and survival during chronic viral infection (2015) (124)
Interleukin-10 from CD4+ follicular regulatory T cells promotes the germinal center response (2017) (123)
TLR9-Targeted Biodegradable Nanoparticles as Immunization Vectors Protect against West Nile Encephalitis (2010) (117)
A dormant TIL phenotype defines non-small cell lung carcinomas sensitive to immune checkpoint blockers (2018) (116)
Generating diversity: transcriptional regulation of effector and memory CD8+ T‐cell differentiation (2010) (112)
UV‐induced somatic mutations elicit a functional T cell response in the YUMMER1.7 mouse melanoma model (2017) (105)
Multicohort analysis reveals baseline transcriptional predictors of influenza vaccination responses (2017) (105)
Differential Localization of Effector and Memory CD8 T Cell Subsets in Lymphoid Organs during Acute Viral Infection (2010) (102)
Epigenetic modifications induced by Blimp-1 Regulate CD8⁺ T cell memory progression during acute virus infection. (2013) (101)
Immune-based antitumor effects of BRAF inhibitors rely on signaling by CD40L and IFNγ. (2014) (101)
A central role for Notch in effector CD8+ T cell differentiation (2014) (97)
Diversity in CD8(+) T cell differentiation. (2009) (96)
Increased Numbers of Preexisting Memory CD8 T Cells and Decreased T-bet Expression Can Restrain Terminal Differentiation of Secondary Effector and Memory CD8 T Cells (2011) (94)
MyD88 Plays a Critical T Cell-Intrinsic Role in Supporting CD8 T Cell Expansion during Acute Lymphocytic Choriomeningitis Virus Infection1 (2008) (92)
The interface between transcriptional and epigenetic control of effector and memory CD8+ T‐cell differentiation (2014) (91)
Sorting and directed transport of membrane proteins during development of hippocampal neurons in culture (2001) (90)
Differential Roles of IL-2 Signaling in Developing versus Mature Tregs. (2018) (89)
Myeloid-targeted immunotherapies act in synergy to induce inflammation and antitumor immunity (2018) (89)
Convergence of multiple signaling pathways is required to coordinately up-regulate mtDNA and mitochondrial biogenesis during T cell activation. (2007) (86)
TRAF3/CYLD mutations identify a distinct subset of human papillomavirus‐associated head and neck squamous cell carcinoma (2017) (86)
Chronic viral infection promotes sustained Th1-derived immunoregulatory IL-10 via BLIMP-1. (2014) (80)
Identification of an Evolutionarily Conserved Transcriptional Signature of CD8 Memory Differentiation That Is Shared by T and B Cells1 (2008) (78)
BCL6b mediates the enhanced magnitude of the secondary response of memory CD8+ T lymphocytes. (2005) (77)
ZEB1, ZEB2, and the miR-200 family form a counterregulatory network to regulate CD8+ T cell fates (2018) (77)
Nurine myeloid dendritic cell‐dependent toll‐like receptor immunity is preserved with aging (2006) (77)
STAT4 and T-bet control follicular helper T cell development in viral infections (2018) (75)
ABC transporters and NR4A1 identify a quiescent subset of tissue-resident memory T cells. (2016) (73)
Clinical Features and Management of Acquired Resistance to PD‐1 Axis Inhibitors in 26 Patients With Advanced Non–Small Cell Lung Cancer (2018) (71)
Reducing mitochondrial ROS improves disease-related pathology in a mouse model of ataxia-telangiectasia. (2013) (67)
The Selective Increase in Caspase-3 Expression in Effector but Not Memory T Cells Allows Susceptibility to Apoptosis1 (2004) (67)
Aging-dependent alterations in gene expression and a mitochondrial signature of responsiveness to human influenza vaccination (2015) (63)
Induction of Telomerase Activity and Maintenance of Telomere Length in Virus-Specific Effector and Memory CD8+ T Cells1 (2003) (61)
Formation of IL-7Rαhigh and IL-7Rαlow CD8 T Cells during Infection Is Regulated by the Opposing Functions of GABPα and Gfi-11 (2008) (60)
Mitochondrial DNA Stress Signalling Protects the Nuclear Genome (2019) (59)
Tissue-resident memory T cell reactivation by diverse antigen-presenting cells imparts distinct functional responses (2020) (58)
Murine [corrected] myeloid dendritic cell-dependent toll-like receptor immunity is preserved with aging. (2006) (57)
Viperin Is Highly Induced in Neutrophils and Macrophages during Acute and Chronic Lymphocytic Choriomeningitis Virus Infection (2010) (56)
Metformin exerts antitumor activity via induction of multiple death pathways in tumor cells and activation of a protective immune response (2018) (55)
Prolonged proinflammatory cytokine production in monocytes modulated by interleukin 10 after influenza vaccination in older adults. (2015) (54)
Smad4 Promotes Differentiation of Effector and Circulating Memory CD8 T Cells but Is Dispensable for Tissue-Resident Memory CD8 T Cells (2015) (54)
CD4⁺ and CD8⁺ T cell-dependent antiviral immunity requires STIM1 and STIM2. (2014) (53)
Intrinsic and extrinsic control of effector T cell survival and memory T cell development (2009) (53)
TLR4 Ligands Lipopolysaccharide and Monophosphoryl Lipid A Differentially Regulate Effector and Memory CD8+ T Cell Differentiation (2014) (52)
The transforming growth factor beta signaling pathway is critical for the formation of CD4 T follicular helper cells and isotype-switched antibody responses in the lung mucosa (2015) (50)
Improved lipid-mediated gene transfer into primary cultures of hippocampal neurons. (1996) (48)
Memory T cells from minor histocompatibility antigen-vaccinated and virus-immune donors improve GVL and immune reconstitution. (2011) (42)
CCR7 expression alters memory CD8 T-cell homeostasis by regulating occupancy in IL-7– and IL-15–dependent niches (2016) (42)
Tick-TOX, it’s time for T cell exhaustion (2019) (41)
The Bcl‐2 family pro‐apoptotic molecule, BNIP3 regulates activation‐induced cell death of effector cytotoxic T lymphocytes (2003) (41)
Reenergizing T cell anti-tumor immunity by harnessing immunometabolic checkpoints and machineries. (2017) (40)
JNK1 Is Essential for CD8+ T Cell-Mediated Tumor Immune Surveillance1 (2005) (39)
T-cell TGF-β signaling abrogation restricts medulloblastoma progression (2014) (38)
A functional subset of CD8+ T cells during chronic exhaustion is defined by SIRPα expression (2019) (37)
Enhanced Expression of Cell Cycle Regulatory Genes in Virus-Specific Memory CD8+ T Cells (2004) (35)
Expression of kinesin superfamily genes in cultured hippocampal neurons (2010) (35)
Cutting Edge: Memory CD8 T Cell Maturation Occurs Independently of CD8αα 1 (2005) (34)
Molecular Signature of CD8+ T Cell Exhaustion during Chronic Viral Infection (DOI:10.1016/j.immuni.2007.09.006) (2007) (34)
Drug Sensitivity and Allele Specificity of First-Line Osimertinib Resistance EGFR Mutations (2020) (33)
O-GlcNAcase targets pyruvate kinase M2 to regulate tumor growth (2019) (32)
IL-7 plays a critical role for the homeostasis of allergen-specific memory CD4 T cells in the lung and airways (2017) (32)
Tuft Cells Inhibit Pancreatic Tumorigenesis in Mice by Producing Prostaglandin D2. (2020) (30)
Edinburgh Research Explorer Formation of IL-7Ralphahigh and IL-7Ralphalow CD8 T cells during infection is regulated by the opposing functions of GABPalpha and Gfi-1 (2009) (29)
IL-2 in the tumor microenvironment is necessary for Wiskott-Aldrich syndrome protein deficient NK cells to respond to tumors in vivo (2016) (27)
A Phase I Study of APX005M and Cabiralizumab with or without Nivolumab in Patients with Melanoma, Kidney Cancer, or Non–Small Cell Lung Cancer Resistant to Anti-PD-1/PD-L1 (2021) (25)
The architectural design of CD8+ T cell responses in acute and chronic infection: Parallel structures with divergent fates (2021) (24)
IL-10 induces a STAT3-dependent autoregulatory loop in TH2 cells that promotes Blimp-1 restriction of cell expansion via antagonism of STAT5 target genes (2016) (23)
Characterization of Diabetogenic CD8+ T Cells (2016) (23)
NK Cell Responses Redefine Immunological Memory (2016) (22)
Immunology: The chronicles of T-cell exhaustion (2017) (20)
Prdm1 Regulates Thymic Epithelial Function To Prevent Autoimmunity (2017) (20)
Differentiation of CD8 T cells in response to acute and chronic viral infections: implications for HIV vaccine development. (2005) (19)
IL‐4 induces a suppressive IL‐10‐producing CD8+ T cell population via a Cdkn2a‐dependent mechanism (2013) (18)
Final Results of a Phase II Prospective Trial Evaluating the Combination of Stereotactic Body Radiotherapy (SBRT) with Concurrent Pembrolizumab in Patients with Metastatic Non-Small Cell Lung Cancer (NSCLC) (2019) (17)
Seasonal Variability and Shared Molecular Signatures of Inactivated Influenza Vaccination in Young and Older Adults (2019) (16)
Transient expression of ZBTB32 in anti-viral CD8+ T cells limits the magnitude of the effector response and the generation of memory (2017) (16)
Metabolic regulation of T cells in the tumor microenvironment by nutrient availability and diet. (2021) (15)
Reinvigorating NIH Grant Peer Review. (2020) (15)
Tumor regression mediated by oncogene withdrawal or erlotinib stimulates infiltration of inflammatory immune cells in EGFR mutant lung tumors (2018) (15)
Active mTORC2 Signaling in Naive T Cells Suppresses Bone Marrow Homing by Inhibiting CXCR4 Expression (2018) (14)
Immunity Resource Molecular Signature of CD 8 + T Cell Exhaustion during Chronic Viral Infection (13)
Probing the Diversity of T Cell Dysfunction in Cancer (2016) (12)
ZEB1 promotes pathogenic Th1 and Th17 cell differentiation in multiple sclerosis (2021) (12)
A STATISTICAL ANALYSIS OF MEMORY CD8 T CELL DIFFERENTIATION : AN APPLICATION OF A HIERARCHICAL STATE SPACE MODEL TO A SHORT TIME COURSE MICROARRAY EXPERIMENT (2007) (11)
How metabolism bridles cytotoxic CD8+ T cells through epigenetic modifications. (2021) (11)
Aberrant CD8+ T-cell responses and memory differentiation upon viral infection of an ataxia-telangiectasia mouse model driven by hyper-activated Akt and mTORC1 signaling. (2011) (11)
IL-7 Knocks the Socs Off Chronic Viral Infection (2011) (9)
MyD 88 Plays a Critical T Cell-Intrinsic Role in Supporting CD 8 T Cell Expansion during Acute Lymphocytic Choriomeningitis Virus Infection 1 (2008) (8)
Stimulation of pp60c-src kinase activity in FDC-P1 cells by polyoma middle-T antigen and hematopoietic growth factors. (1989) (8)
The landscape of novel and complementary targets for immunotherapy: an analysis of gene expression in the tumor microenvironment (2019) (8)
Clonal lineage tracing reveals mechanisms skewing CD8+ T cell fate decisions in chronic infection (2022) (8)
Myristylation of pp60c-src is not required for complex formation with polyomavirus middle-T antigen (1990) (7)
Celebrating Diversity in Memory T Cells (2014) (7)
Universal Principled Review: A Community-Driven Method to Improve Peer Review (2019) (5)
BRAF-targeted therapy alters the functions of intratumoral CD4+ T cells to inhibit melanoma progression (2014) (5)
Correction: STAT4 and T-bet control follicular helper T cell development in viral infections (2018) (5)
Final Results of a Phase I Prospective Trial Evaluating the Combination of Stereotactic Body Radiation Therapy (SBRT) with Concurrent Pembrolizumab in Patients with Metastatic Non-Small Cell Lung Cancer (NSCLC) or Melanoma (2018) (5)
Correction: The transforming growth factor beta signaling pathway is critical for the formation of CD4 T follicular helper cells and isotype-switched antibody responses in the lung mucosa (2015) (4)
T Cell Metabolism in a State of Flux. (2019) (4)
Infection Is Regulated by the Opposing Functions of GABP and Gfi-1 (2008) (4)
The role of CD36 in macrophage lipid metabolism and function in tumor microenvironment (2020) (4)
1-deoxysphingolipids bind to COUP-TF to modulate lymphatic and cardiac cell development. (2021) (4)
Immunoediting instructs tumor metabolic reprogramming to support immune evasion. (2023) (3)
Parallels between the anti-Viral State and the Irradiated State. (2020) (3)
Trials and Tribble-ations of tissue TRM cells (2018) (3)
Final results of a phase I prospective trial evaluating the combination of stereotactic body radiotherapy (SBRT) with concurrent pembrolizumab in patients with metastatic non-small cell lung cancer (NSCLC) or melanoma. (2018) (3)
Generating CD8 T cell heterogeneity: attack of the clones. (2013) (3)
P3.02c-048 A Phase I/II Trial Evaluating the Combination of Stereotactic Body Radiotherapy and Pembrolizumab in Metastatic NSCLC: Topic: IT (2017) (3)
The tumor growth factor beta signaling pathway is critical for the formation of CD 4 T follicular 1 helper cells and isotype-switched antibody responses in the lung mucosa 2 3 (3)
Patients with HIV-associated cancers have evidence of increased T cell dysfunction and exhaustion prior to cancer diagnosis (2022) (3)
SnapShot: Cancer immunoediting (2022) (2)
Oxidized Lipids and CD36-Mediated Lipid Peroxidation in CD8 T Cells Suppress Anti-Tumor Immune Responses (2020) (2)
Eicosanoids in the pancreatic tumor microenvironment – a multicellular, multifaceted progression (2021) (2)
Regulating the diverse outcomes of interferon's interference. (2014) (2)
Motility Matters: How CD8+ T-Cell Trafficking Influences Effector and Memory Cell Differentiation. (2021) (2)
Corrigendum: Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin (2006) (2)
Faculty Opinions recommendation of Distinct CD4+ helper T cells involved in primary and secondary responses to infection. (2012) (2)
JEM women in STEM: Unique journeys with a common purpose (2020) (1)
On Our Way to a Better Understanding of CD8 T Cell Differentiation and Memory T Cell Development. (2008) (1)
Dispensable for Tissue-Resident Memory and Circulating Memory CD 8 T Cells but Is Smad 4 Promotes Differentiation of Effector (2015) (1)
Decreasing the TORC on memory CD8 T‐cell formation (2009) (1)
Like parent, like child: inheritance of effector CD8+ T cell traits. (2010) (1)
Mitochondrial DNA stress signalling protects the nuclear genome (2019) (1)
Immigration in science (2020) (1)
Regulate Effector and Memory CD 8 Monophosphoryl Lipid A Differentially TLR 4 Ligands Lipopolysaccharide and (2014) (1)
T-bet in Tfh cells: Now you see me, now you don’t (2018) (1)
Elevated murine HB-EGF confers sensitivity to diphtheria toxin in EGFR-mutant lung adenocarcinoma (2021) (1)
Differential localization of effector and memory T cell subsets (83.16) (2009) (1)
Cells Allows Susceptibility to Apoptosis Expression in Effector but Not Memory T The Selective Increase in Caspase-3 (2004) (0)
Inflammation regulates memory CD8 T cell development (85.3) (2007) (0)
SMAD4 and TGFβ are architects of inverse genetic programs during fate-determination of antiviral memory CD8 T cells (2021) (0)
Trials and Tribble-ations of tissue TRM cells (2018) (0)
InfectionAcute Lymphocytic Choriomeningitis Virus in Supporting CD8 T Cell Expansion during MyD88 Plays a Critical T Cell-Intrinsic Role (2008) (0)
All Memory Lymphocytes Share a Common Differentiation Program. (2006) (0)
FoxO1 directly regulates the expression of PD-1 and sustains viral specific CD8+ T cell responses during chronic infection (IRM4P.501) (2014) (0)
Bcl6 is required for the development of T follicular helper cells marked by downregulation of P-selectin glycoprotein ligand-1 (46.7) (2009) (0)
Glycerol channel aquaporin-9 plays a critical role in the formation of memory CD8 T cells after viral infection (VIR4P.1006) (2014) (0)
Immunity to virus infection (excluding retroviruses) 2 (WS-025b) Chairpersons: Tsukasa Seya, Iain Campbell (2010) (0)
Transcriptional mapping of the anti-viral T cell response shows that impaired memory differentiation causes T cell dysfunction (2006) (0)
Abstract 1613: A hypoxia-driven transcriptional program characterizes acquired resistance to immune checkpoint inhibitors in lung cancer (2021) (0)
Illuminating histidine phosphorylation in the pancreatic tumor microenvironment (2022) (0)
766 Exposure to ultraviolet light enhances anti-tumor immunity and response to immunotherapy in a mouse model of melanoma (2017) (0)
Immunometabolic editing: a new type of immunoediting in tumorigenesis (TUM7P.1027) (2015) (0)
A microglia-CD4+ T cell partnership generates protective anti-tumor immunity to glioblastoma (2022) (0)
IL-7 plays a critical role for the homeostasis of allergen-specific memory CD4 T cells in the lung and airways (2017) (0)
IL-10-IL-21-STAT3 axis regulates memory CD8 T cell development (110.9) (2012) (0)
Indiscriminate nature of lung resident CD8+ TRM cells reactivation and their varied reactivation profiles (2019) (0)
Counting on You: How MHC Tetramers Revolutionized the Study of T Cell Memory and CD8+ T Cell Exhaustion (2021) (0)
A dormant TIL phenotype defines non-small cell lung carcinomas sensitive to immune checkpoint blockers (2018) (0)
EGFR+ lung adenocarcinomas coopt alveolar macrophage metabolism and function to support EGFR signaling and growth (2023) (0)
Abstract B063: Unsaturated fatty acids cause CD8+ T cell exhaustion in melanoma (2016) (0)
InfectionLymphocytic Choriomeningitis Virus Macrophages during Acute and Chronic Viperin Is Highly Induced in Neutrophils and (2010) (0)
Abstract IA03: Anti-tumor T cells: You are what you eat (2016) (0)
Inflammation regulates memory CD8 T cell development (2007) (0)
Unsaturated fatty acids suppress anti-tumor T cell function. (2016) (0)
Faculty Opinions recommendation of The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2. (2011) (0)
Lit Lunch 2_13_15 Damian: (2015) (0)
P3.02c-088 Acquired Resistance to Programmed Death-1 Axis Inhibitors in Non-Small Cell Lung Cancer (NSCLC): Topic: IT Biomarkers (2017) (0)
Cells Secondary Effector and Memory CD8 T Can Restrain Terminal Differentiation of CD8 T Cells and Decreased T-bet Expression Increased Numbers of Preexisting Memory (2011) (0)
Smad signaling determines the fate of activated CTLs via multiple intersecting signaling pathways (2019) (0)
Sorting and directed transpor during development of hippo (2016) (0)
Notch is a signal integrating hub that controls differentiation of effector CD8+ T cells (LYM7P.614) (2015) (0)
Virus-Specific Effector and Memory CD 8 Maintenance of Telomere Length in Induction of Telomerase Activity and (2002) (0)
ANALYSIS OF MEMORY CD 8 T CELL DIFFERENTIATION 443 done in the context of a large research effort to understand immune memory in (2007) (0)
Faculty of 1000 evaluation for Marginating dendritic cells of the tumor microenvironment cross-present tumor antigens and stably engage tumor-specific T cells. (2016) (0)
Immunometabolism at the crossroads of obesity and cancer-a Keystone Symposia report. (2023) (0)
IL‐7 Receptor alpha expression marks CD8 T cells with increased proliferative capacity and ability to transduce AKT signals from common gamma receptor cytokines (2008) (0)
Faculty Opinions recommendation of Memory T cells persisting within the brain after local infection show functional adaptations to their tissue of residence. (2010) (0)
CD8 Cells Dispensable for Tissue-Resident Memory and Circulating Memory CD8 T Cells but Is Smad4 Promotes Differentiation of Effector (2015) (0)
Transcriptional Mapping of T Cell Memory Reveals That Chronic Viral Infection Arrests Memory Differentiation. (2005) (0)
Faculty Opinions recommendation of Rapid in vivo conversion of effector T cells into Th2 cells during helminth infection. (2012) (0)
Abstract A09: Impaired HLA Class I antigen processing and presentation as a mechanism of acquired Rrsistance to immune checkpoint inhibitors in lung cancer (2018) (0)
Multiomics atlas-assisted discovery of transcription factors enables specific cell state programming (2023) (0)
Abstract 2531: a (2022) (0)
A functional subset of CD8+ T cells during chronic exhaustion is defined by SIRPα expression (2019) (0)
Abstract A083: Modulation of the immune system as a strategy to treat EGFR mutant lung adenocarcinoma (2016) (0)
Su.66. Memory T-Cells in Mice and Humans Share a Common Molecular Program of Differentiation Regardless of Phenotype, Lineage Or Species (2006) (0)
Listeria monocytogenes of CD8 T Cell Memory by Recombinant A Specific Role for B Cells in the Generation (2003) (0)
ST6Gal I promotes rapid IL-2Rα expression and early proliferation of terminal effector CD8 T cells (46.8) (2011) (0)
Early CD8 T cell proliferative heterogeneity entails diverse memory differentiation programs (2007) (0)
Immunity The Regulation of CD 8 + T Cell Exhaustion by FoxO 1 prime therapeutic target for enhancing T cell responses during certain forms of chronic infection and cancer (2014) (0)
ST6Gal I promotes rapid IL-2R{alpha} expression and early proliferation of terminal effector CD8 T cells (2011) (0)
Abstract B48: CD40-agonist treatment can prime the inflammatory response of macrophages and reverse checkpoint inhibitor resistance in melanoma (2022) (0)
A dynamic (epi)genomic landscape of CD8+ T cell differentiation drives cell-fate decisions (2016) (0)
NK cell activity promotes liver damage and chronic viral infection (2014) (0)
antigen.formation with polyomavirus middle-T Myristylation of pp60c-src is not required for (2013) (0)
616 UV-induced somatic mutations elicit a functional T cell response and tumor regression in BRAFV600E, CDKN2A-/-, PTEN-/- melanoma model (2016) (0)
Abstract 3287: A bedside to bench study of anti-PD-1, anti-CD40, and anti-CSF1R indicates that more is not necessarily better (2023) (0)

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