Susan M. Gasser

Q: What Schools Are Affiliated With Susan M. Gasser

Susan M. Gasser is affiliated with the following schools: University of Basel, University of Geneva, University of California, San Francisco

Susan M. Gasser's AcademicInfluence.com Rankings

Susan M. Gasser

Biology

#3844

World Rank

#5828

Historical Rank

Molecular Biology

#523

World Rank

#536

Historical Rank

biology Degrees

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Biology

Susan M. Gasser's Degrees

PhD Molecular Biology University of Basel

Why Is Susan M. Gasser Influential?

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According to Wikipedia, Susan M. Gasser is a Swiss molecular biologist. From 2004 to 2019 she was the director of the Friedrich Miescher Institute for Biomedical Research in Basel, Switzerland, where she also led a research group from 2004 until 2021. She was in parallel professor of molecular biology at the University of Basel until April 2021. Since January 2021, Susan Gasser is director of the ISREC Foundation, which supports translational cancer research. She is also professor invité at the University of Lausanne in the department of fundamental microbiology. She is an expert in quantitative biology and studies epigenetic inheritance and genome stability. Recipient of multiple swiss and European awards, she was named member of the US Academy of Sciences in 2022.

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Susan M. Gasser's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Histone H3 and H4 N-termini interact with SIR3 and SIR4 proteins: A molecular model for the formation of heterochromatin in yeast (1995) (801)
Recruitment of the INO80 Complex by H2A Phosphorylation Links ATP-Dependent Chromatin Remodeling with DNA Double-Strand Break Repair (2004) (656)
Step-Wise Methylation of Histone H3K9 Positions Heterochromatin at the Nuclear Periphery (2012) (541)
Crosstalk between histone modifications during the DNA damage response. (2009) (527)
Cohabitation of scaffold binding regions with upstream/enhancer elements of three developmentally regulated genes of D. melanogaster (1986) (514)
Relocalization of Telomeric Ku and SIR Proteins in Response to DNA Strand Breaks in Yeast (1999) (490)
Metaphase chromosome structure. Involvement of topoisomerase II. (1986) (489)
The clustering of telomeres and colocalization with Rap1, Sir3, and Sir4 proteins in wild-type Saccharomyces cerevisiae (1996) (473)
Automatic tracking of individual fluorescence particles: application to the study of chromosome dynamics (2005) (460)
The nuclear envelope and transcriptional control (2007) (457)
SIR3 and SIR4 proteins are required for the positioning and integrity of yeast telomeres (1993) (420)
Functional Targeting of DNA Damage to a Nuclear Pore-Associated SUMO-Dependent Ubiquitin Ligase (2008) (403)
Nuclear pore association confers optimal expression levels for an inducible yeast gene (2006) (400)
Chromosome Dynamics in the Yeast Interphase Nucleus (2001) (399)
A glimpse at chromosomal order (1987) (391)
Redistribution of Silencing Proteins from Telomeres to the Nucleolus Is Associated with Extension of Life Span in S. cerevisiae (1997) (388)
Mutation of yeast Ku genes disrupts the subnuclear organization of telomeres (1998) (385)
DNA polymerase stabilization at stalled replication forks requires Mec1 and the RecQ helicase Sgs1 (2003) (364)
Distinct roles for SWR1 and INO80 chromatin remodeling complexes at chromosomal double‐strand breaks (2007) (343)
The histone code at DNA breaks: a guide to repair? (2005) (324)
Visualizing Chromatin Dynamics in Interphase Nuclei (2002) (320)
Localization of RAP1 and topoisomerase II in nuclei and meiotic chromosomes of yeast (1992) (307)
Live Imaging of Telomeres yKu and Sir Proteins Define Redundant Telomere-Anchoring Pathways in Yeast (2002) (305)
Long-range compaction and flexibility of interphase chromatin in budding yeast analyzed by high-resolution imaging techniques. (2004) (292)
How mitochondria import proteins. (1984) (291)
Evidence for silencing compartments within the yeast nucleus: a role for telomere proximity and Sir protein concentration in silencer-mediated repression. (1996) (289)
Separation of silencing from perinuclear anchoring functions in yeast Ku80, Sir4 and Esc1 proteins (2004) (287)
The yeast Sgs1p helicase acts upstream of Rad53p in the DNA replication checkpoint and colocalizes with Rad53p in S-phase-specific foci. (2000) (281)
Increased mobility of double-strand breaks requires Mec1, Rad9 and the homologous recombination machinery (2012) (278)
The molecular biology of the SIR proteins. (2001) (265)
The organisation of chromatin loops: characterization of a scaffold attachment site (1986) (257)
Localization of Sir2p: the nucleolus as a compartment for silent information regulators (1997) (254)
Nuclear compartments and gene regulation. (1999) (247)
The function of nuclear architecture: a genetic approach. (2004) (242)
Gene regulation through nuclear organization (2007) (240)
Import of proteins into mitochondria. Energy-dependent uptake of precursors by isolated mitochondria. (1982) (240)
The telobox, a Myb-related telomeric DNA binding motif found in proteins from yeast, plants and human. (1996) (226)
ORC and the intra-S-phase checkpoint: a threshold regulates Rad53p activation in S phase. (2002) (218)
Chromosomal ARS and CEN elements bind specifically to the yeast nuclear scaffold (1988) (216)
The spatial dynamics of tissue-specific promoters during C. elegans development. (2010) (211)
Replisome instability, fork collapse, and gross chromosomal rearrangements arise synergistically from Mec1 kinase and RecQ helicase mutations. (2005) (210)
Chromatin and nucleosome dynamics in DNA damage and repair (2017) (204)
Distortion of the DNA double helix by RAP1 at silencers and multiple telomeric binding sites. (1993) (204)
Import of proteins into mitochondria. Energy-dependent, two-step processing of the intermembrane space enzyme cytochrome b2 by isolated yeast mitochondria. (1982) (201)
Chromatin Movement in the Maintenance of Genome Stability (2013) (199)
The carboxy termini of Sir4 and Rap1 affect Sir3 localization: evidence for a multicomponent complex required for yeast telomeric silencing (1995) (196)
The Positioning and Dynamics of Origins of Replication in the Budding Yeast Nucleus (2001) (192)
Studies on scaffold attachment sites and their relation to genome function. (1989) (191)
Yeast telomerase and the SUN domain protein Mps3 anchor telomeres and repress subtelomeric recombination. (2009) (189)
Histone degradation in response to DNA damage enhances chromatin dynamics and recombination rates (2017) (186)
Structure and Function in the Budding Yeast Nucleus (2012) (184)
Sir-Mediated Repression Can Occur Independently of Chromosomal and Subnuclear Contexts (2004) (182)
Ino80 Chromatin Remodeling Complex Promotes Recovery of Stalled Replication Forks (2008) (179)
A cytosolic NAD‐dependent deacetylase, Hst2p, can modulate nucleolar and telomeric silencing in yeast (2001) (177)
Mechanistically distinct roles for Sgs1p in checkpoint activation and replication fork maintenance (2005) (173)
Heterochromatin protein 1: don't judge the book by its cover! (2006) (168)
The nuclear envelope--a scaffold for silencing? (2009) (159)
Targeted INO80 enhances subnuclear chromatin movement and ectopic homologous recombination. (2012) (158)
ATR/Mec1: coordinating fork stability and repair. (2009) (157)
Histone H3K9 methylation is dispensable for Caenorhabditis elegans development but suppresses RNA:DNA hybrid-associated repeat instability (2016) (156)
RAP-1 factor is necessary for DNA loop formation in vitro at the silent mating type locus HML (1989) (153)
SWR1 and INO80 chromatin remodelers contribute to DNA double-strand break perinuclear anchorage site choice. (2014) (150)
Casein kinase II phosphorylates the eukaryote‐specific C‐terminal domain of topoisomerase II in vivo. (1992) (148)
On TADs and LADs: Spatial Control Over Gene Expression. (2016) (147)
Perinuclear Anchoring of H3K9-Methylated Chromatin Stabilizes Induced Cell Fate in C. elegans Embryos (2015) (147)
A role for the Cdc7 kinase regulatory subunit Dbf4p in the formation of initiation-competent origins of replication. (1999) (138)
Telomeres and the functional architecture of the nucleus. (1993) (135)
Positions of Potential:Nuclear Organization and Gene Expression (2001) (135)
The functional importance of telomere clustering: global changes in gene expression result from SIR factor dispersion. (2009) (134)
Imported mitochondrial proteins cytochrome b2 and cytochrome c1 are processed in two steps. (1982) (133)
An EDMD Mutation in C. elegans Lamin Blocks Muscle-Specific Gene Relocation and Compromises Muscle Integrity (2011) (132)
Scaffold attachment of DNA loops in metaphase chromosomes. (1988) (124)
RecQ helicases: multiple roles in genome maintenance. (2003) (124)
Reconstitution of yeast silent chromatin: multiple contact sites and O-AADPR binding load SIR complexes onto nucleosomes in vitro. (2009) (120)
The budding yeast nucleus. (2010) (120)
SIR proteins and the assembly of silent chromatin in budding yeast. (2013) (117)
Checkpoint kinases and the INO80 nucleosome remodeling complex enhance global chromatin mobility in response to DNA damage (2013) (112)
The Origin Recognition Complex Functions in Sister-Chromatid Cohesion in Saccharomyces cerevisiae (2007) (111)
Long-range silencing and position effects at telomeres and centromeres: parallels and differences (2003) (110)
Histones and histone modifications in perinuclear chromatin anchoring: from yeast to man (2016) (109)
An N-terminal domain of Dbf4p mediates interaction with both origin recognition complex (ORC) and Rad53p and can deregulate late origin firing (2002) (109)
The outer membrane of yeast mitochondria: isolation of outside‐out sealed vesicles (1983) (108)
ATP-Dependent Chromatin Remodeling and DNA Double-Strand Break Repair (2005) (108)
Structural Maintenance of Chromosomes Protein C-terminal Domains Bind Preferentially to DNA with Secondary Structure* (1998) (105)
A dual role of H4K16 acetylation in the establishment of yeast silent chromatin (2011) (103)
Nucleosome remodelers in double-strand break repair. (2013) (97)
The PIAS homologue Siz2 regulates perinuclear telomere position and telomerase activity in budding yeast (2011) (97)
Epigenetics in Saccharomyces cerevisiae. (2013) (97)
The dynamics of yeast telomeres and silencing proteins through the cell cycle. (2000) (96)
PolySUMOylation by Siz2 and Mms21 triggers relocation of DNA breaks to nuclear pores through the Slx5/Slx8 STUbL (2016) (95)
Regulation of recombination at yeast nuclear pores controls repair and triplet repeat stability (2015) (94)
Nuclear organization in genome stability: SUMO connections (2011) (94)
Repeat DNA in genome organization and stability. (2015) (94)
INO80 and SWR complexes: relating structure to function in chromatin remodeling. (2014) (93)
Drosophila scaffold-attached regions bind nuclear scaffolds and can function as ARS elements in both budding and fission yeasts (1990) (92)
Myosin-like proteins 1 and 2 are not required for silencing or telomere anchoring, but act in the Tel1 pathway of telomere length control. (2002) (90)
Cooperation at a distance between silencers and proto‐silencers at the yeast HML locus. (1996) (90)
Controlled exchange of chromosomal arms reveals principles driving telomere interactions in yeast. (2008) (88)
LifeTime and improving European healthcare through cell-based interceptive medicine (2020) (87)
Mechanisms of heterochromatin subnuclear localization. (2013) (86)
Temporal separation of replication and recombination requires the intra-S checkpoint (2005) (86)
Cohesin and the nucleolus constrain the mobility of spontaneous repair foci (2013) (86)
Silent chromatin at the middle and ends: lessons from yeasts (2009) (85)
Replication foci dynamics: replication patterns are modulated by S‐phase checkpoint kinases in fission yeast (2007) (84)
Multiple pathways for telomere tethering: functional implications of subnuclear position for heterochromatin formation. (2004) (84)
Visualization of Chromatin Decompaction and Break Site Extrusion as Predicted by Statistical Polymer Modeling of Single-Locus Trajectories. (2017) (83)
Visualizing yeast chromosomes and nuclear architecture. (2010) (83)
Mec1, INO80, and the PAF1 complex cooperate to limit transcription replication conflicts through RNAPII removal during replication stress (2016) (83)
Intracellular trafficking of yeast telomerase components (2002) (82)
Chromosome dynamics: the SMC protein family. (1998) (81)
An N‐terminal acidic region of Sgs1 interacts with Rpa70 and recruits Rad53 kinase to stalled forks (2012) (81)
Nuclear Geometry and Rapid Mitosis Ensure Asymmetric Episome Segregation in Yeast (2011) (81)
Import of proteins into mitochondria. In vitro studies on the biogenesis of the outer membrane. (1983) (80)
Locking the genome: nuclear organization and cell fate. (2011) (78)
TORC2 signaling pathway guarantees genome stability in the face of DNA strand breaks. (2013) (77)
Regulation of Nuclear Positioning and Dynamics of the Silent Mating Type Loci by the Yeast Ku70/Ku80 Complex (2008) (77)
Meiotic behaviours of chromosomes and microtubules in budding yeast: relocalization of centromeres and telomeres during meiotic prophase (1998) (76)
Nuclear Actin and Actin-Binding Proteins in DNA Repair. (2019) (76)
A sense of the end. (2000) (76)
Chromatin states and nuclear organization in development — a view from the nuclear lamina (2015) (74)
Improved methods for the isolation of individual and clustered mitotic chromosomes. (1987) (72)
Repetitive transgenes in C. elegans accumulate heterochromatic marks and are sequestered at the nuclear envelope in a copy-number- and lamin-dependent manner. (2010) (71)
Modules for cloning‐free chromatin tagging in Saccharomyces cerevisae (2008) (71)
RecQ-like helicases: the DNA replication checkpoint connection. (2000) (70)
ORC-dependent and origin-specific initiation of DNA replication at defined foci in isolated yeast nuclei. (1997) (69)
DNA loops: structural and functional properties of scaffold‐attached regions (1992) (69)
Relation of chromosome structure and gene expression. (1987) (68)
Identification and purification of a protein that binds the yeast ARS consensus sequence (1991) (68)
Regulation of topoisomerase II by phosphorylation: a role for casein kinase II. (1993) (68)
DNA topoisomerase II mutations and resistance to anti‐tumor drugs (1995) (68)
Turning telomeres off and on. (2001) (67)
The processing of double-strand breaks and binding of single-strand-binding proteins RPA and Rad51 modulate the formation of ATR-kinase foci in yeast (2007) (67)
Actin-related proteins in the nucleus: life beyond chromatin remodelers. (2010) (67)
Repressive Chromatin in Caenorhabditis elegans: Establishment, Composition, and Function (2018) (67)
The INO80 remodeller in transcription, replication and repair (2017) (66)
Active chromatin marks drive spatial sequestration of heterochromatin in C. elegans nuclei (2019) (65)
Chromosome looping in yeast (2005) (63)
Replication Checkpoint: Tuning and Coordination of Replication Forks in S Phase (2013) (63)
The composition and morphology of yeast nuclear scaffolds. (1990) (62)
Telomeres and telomerase. (1999) (61)
Promoter- and RNA polymerase II–dependent hsp-16 gene association with nuclear pores in Caenorhabditis elegans (2013) (60)
Nuclear scaffold attachment stimulates, but is not essential for ARS activity in Saccharomyces cerevisiae: analysis of the Drosophila ftz SAR. (1990) (60)
Nuclear organization and silencing: putting things in their place (2002) (59)
Chromatin organization and dynamics in double-strand break repair. (2017) (58)
Ku‐deficient yeast strains exhibit alternative states of silencing competence (2001) (57)
Yeast PP4 interacts with ATR homolog Ddc2-Mec1 and regulates checkpoint signaling. (2015) (57)
Actin-Related Protein Arp6 Influences H2A.Z-Dependent and -Independent Gene Expression and Links Ribosomal Protein Genes to Nuclear Pores (2010) (55)
Analysis of etoposide binding to subdomains of human DNA topoisomerase II alpha in the absence of DNA. (2001) (55)
RecQ helicases: at the heart of genetic stability (2002) (52)
A homotrimer-heterotrimer switch in Sir2 structure differentiates rDNA and telomeric silencing. (2006) (52)
Heterochromatin Protein 1β (HP1β) has distinct functions and distinct nuclear distribution in pluripotent versus differentiated cells (2015) (52)
The regulation of euchromatin and heterochromatin by histones in yeast (1995) (52)
Methods for visualizing chromatin dynamics in living yeast. (2004) (50)
INO80-C and SWR-C: guardians of the genome. (2015) (50)
Structural basis for the role of the Sir3 AAA+ domain in silencing: interaction with Sir4 and unmethylated histone H3K79. (2011) (49)
Imaging the asymmetrical DNA bend induced by repressor activator protein 1 with scanning tunneling microscopy. (1994) (49)
Topoisomerase II forms multimers in vitro: effects of metals, beta-glycerophosphate, and phosphorylation of its C-terminal domain (1994) (49)
Chromosome Dynamics in Response to DNA Damage. (2018) (49)
The nucleolus: Nucleolar space for RENT (1999) (49)
The function of telomere clustering in yeast: the circe effect. (2004) (49)
Ribosome biogenesis factors bind a nuclear envelope SUN domain protein to cluster yeast telomeres (2011) (48)
RPA Mediates Recruitment of MRX to Forks and Double-Strand Breaks to Hold Sister Chromatids Together. (2016) (47)
Casein kinase II copurifies with yeast DNA topoisomerase II and re-activates the dephosphorylated enzyme. (1993) (46)
Structural Basis of Mec1-Ddc2-RPA Assembly and Activation on Single-Stranded DNA at Sites of Damage. (2017) (44)
Challenges and guidelines toward 4D nucleome data and model standards (2018) (44)
Functional Characterization of the N Terminus of Sir3p (1998) (43)
Nuclear organization and transcriptional silencing in yeast (1996) (43)
Telomere maintenance and gene repression: a common end? (1994) (43)
Taz1p and Teb1p, two telobox proteins in Schizosaccharomyces pombe, recognize different telomere-related DNA sequences. (1999) (42)
Guidelines for DNA recombination and repair studies: Cellular assays of DNA repair pathways (2019) (41)
SIR-nucleosome interactions: structure-function relationships in yeast silent chromatin. (2013) (41)
Subtelomeric factors antagonize telomere anchoring and Tel1‐independent telomere length regulation (2006) (40)
From snapshots to moving pictures: new perspectives on nuclear organization. (2001) (40)
Establishment of H3K9-methylated heterochromatin and its functions in tissue differentiation and maintenance (2022) (39)
Synergistic lethality between BRCA1 and H3K9me2 loss reflects satellite derepression (2019) (38)
MAP kinase signaling induces nuclear reorganization in budding yeast (2000) (38)
RAP1 stimulates single- to double-strand association of yeast telomeric DNA: implications for telomere-telomere interactions. (1994) (38)
Caenorhabditis elegans Heterochromatin protein 1 (HPL-2) links developmental plasticity, longevity and lipid metabolism (2011) (37)
The shelterin protein POT-1 anchors Caenorhabditis elegans telomeres through SUN-1 at the nuclear periphery (2013) (37)
Targeting Sir proteins to sites of action: a general mechanism for regulated repression. (1998) (36)
Sif2p interacts with the Sir4p amino-terminal domain and antagonizes telomeric silencing in yeast (1998) (36)
TORC2—a new player in genome stability (2014) (36)
Redundancy, insult-specific sensors and thresholds: unlocking the S-phase checkpoint response. (2004) (34)
Chromosome Structure: Coiling up chromosomes (1995) (33)
Dot1 binding induces chromatin rearrangements by histone methylation-dependent and -independent mechanisms (2011) (32)
γH2A is a component of yeast heterochromatin required for telomere elongation (2011) (31)
Phosphorylation of the C-terminal domain of yeast topoisomerase II by casein kinase II affects DNA-protein interaction. (1994) (31)
Cell cycle-dependent phosphorylation of Rad53 kinase by Cdc5 and Cdc28 modulates checkpoint adaptation (2010) (31)
Distinct roles for SWR 1 and INO 80 chromatin remodeling complexes at chromosomal double-strand breaks (2013) (31)
Semi-conservative replication in yeast nuclear extracts requires Dna2 helicase and supercoiled template. (1998) (30)
Analysis of nuclear organization in Saccharomyces cerevisiae. (1999) (30)
Dimerization of Sir3 via its C‐terminal winged helix domain is essential for yeast heterochromatin formation (2013) (28)
Early initiation of a replication origin tethered at the nuclear periphery (2010) (28)
Loss of an H3K9me anchor rescues laminopathy-linked changes in nuclear organization and muscle function in an Emery-Dreifuss muscular dystrophy model (2020) (28)
The positioning of yeast telomeres depends on SIR3, SIR4, and the integrity of the nuclear membrane. (1993) (27)
Ectopic expression of inactive forms of yeast DNA topoisomerase II confers resistance to the anti-tumour drug, etoposide. (1996) (27)
Lte1, Cdc14 and MEN‐controlled Cdk inactivation in yeast coordinate rDNA decompaction with late telophase progression (2009) (27)
Chromatin: A sticky silence (1996) (27)
Preparation and characterization of yeast nuclear extracts for efficient RNA polymerase B (II)-dependent transcription in vitro. (1990) (27)
Caspases 3 and 7: Key Mediators of Mitochondrial Events of Apoptosis (2006) (27)
Cyclin B-Cdk1 Kinase Stimulates ORC- and Cdc6-Independent Steps of Semiconservative Plasmid Replication in Yeast Nuclear Extracts (1999) (27)
Meiosis-specific prophase-like pathway controls cleavage-independent release of cohesin by Wapl phosphorylation (2018) (26)
Multiple pathways tether telomeres and silent chromatin at the nuclear periphery: functional implications for sir-mediated repression. (2005) (26)
DNA Damage-Induced Nucleosome Depletion Enhances Homology Search Independently of Local Break Movement. (2020) (25)
In and out of the Replication Factory (2006) (25)
Biosynthesis of the ubiquinol-cytochrome c reductase complex in yeast. Characterization of precursor forms of the 44-kDa, 40-kDa and 17-kDa subunits and identification of individual messenger RNAs for these and other imported subunits of the complex. (1983) (24)
New systems for replicating DNA in vitro. (1998) (24)
Roles for nuclear organization in the maintenance of genome stability. (2010) (24)
Regulating Repression: Roles for the Sir4 N-Terminus in Linker DNA Protection and Stabilization of Epigenetic States (2012) (24)
Posttranslational modifications of repair factors and histones in the cellular response to stalled replication forks. (2009) (23)
Replication origins, factors and attachment sites. (1991) (23)
Epigenetics and Disease (2011) (22)
How Broken DNA Finds Its Template for Repair : A Computational Approach(Statistical Physics and Topology of Polymers with Ramifications to Structure and Function of DNA and Proteins) (2011) (21)
Repressor Activator Protein 1 and Its Ligands: Organising Chromatin Domains (1995) (21)
5 The Nucleus and Nucleocytoplasmic Transport in Saccharomyces cerevisiae (1997) (21)
H3K9me selectively blocks transcription factor activity and ensures differentiated tissue integrity (2021) (21)
RecQ helicases and genome stability: lessons from model organisms and human disease. (2002) (21)
Nuclear organization in DNA end processing: Telomeres vs double-strand breaks. (2015) (20)
Spatial segregation of heterochromatin: Uncovering functionality in a multicellular organism (2016) (20)
Damage-induced chromatome dynamics link Ubiquitin ligase and proteasome recruitment to histone loss and efficient DNA repair. (2021) (19)
The regulation of DNA topoisomerase II by casein kinase II. (1994) (19)
Modulation of drug sensitivity in yeast cells by the ATP-binding domain of human DNA topoisomerase IIalpha. (2003) (19)
Multi-author Review¶Epigenetic control of transcription¶Introduction: the genetics of epigenetics (1998) (18)
The MRX Complex Ensures NHEJ Fidelity through Multiple Pathways Including Xrs2-FHA–Dependent Tel1 Activation (2016) (18)
Spatially confined polymer chains: implications of chromatin fibre flexibility and peripheral anchoring on telomere–telomere interaction (2006) (18)
[32] Import of polypeptides into isolated yeast mitochondria (1983) (17)
Chromatin modifiers and remodellers in DNA repair and signalling (2017) (17)
A molecular dissection of nuclear function (2003) (17)
Asymmetric Processing of DNA Ends at a Double-Strand Break Leads to Unconstrained Dynamics and Ectopic Translocation. (2018) (17)
Underappreciated Roles of DNA Polymerase δ in Replication Stress Survival. (2021) (17)
Topoisomerase II: its functions and phosphorylation. (1992) (17)
Measuring limits of telomere movement on nuclear envelope. (2006) (16)
The yeast protein encoded by PUB1 binds T-rich single stranded DNA (1994) (16)
Heterochromatic foci and transcriptional repression by an unstructured MET-2/SETDB1 co-factor LIN-65 (2019) (15)
Remodelers move chromatin in response to DNA damage (2014) (15)
Visualizing the spatiotemporal dynamics of DNA damage in budding yeast. (2015) (14)
Mutations in the C-terminal domain of topoisomerase II affect meiotic function and interaction with the casein kinase 2 β subunit (1999) (14)
The Importance of Satellite Sequence Repression for Genome Stability. (2017) (14)
Automatic tracking of particles in dynamic fluorescence microscopy (2003) (12)
LSM2-8 and XRN-2 contribute to the silencing of H3K27me3-marked genes through targeted RNA decay (2019) (12)
A Rad53 Independent Function of Rad9 Becomes Crucial for Genome Maintenance in the Absence of the RecQ Helicase Sgs1 (2013) (11)
Disease-associated DNA2 nuclease–helicase protects cells from lethal chromosome under-replication (2020) (11)
Nuclear Architecture: Past and Future Tense. (2016) (11)
Ectopic expression of human topoisomerase IIα fragments and etoposide resistance in mammalian cells (2000) (11)
Nuclear organization and silencing: trafficking of Sir proteins. (1998) (11)
The formation and sequestration of heterochromatin during development (2013) (10)
Argonaute NRDE-3 and MBT domain protein LIN-61 redundantly recruit an H3K9me3 HMT to prevent embryonic lethality and transposon expression (2020) (10)
A Role for the Mre11-Rad50-Xrs2 Complex in Gene Expression and Chromosome Organization. (2020) (10)
Epigenetics and disease : pharmaceutical opportunities (2011) (10)
SUMO wrestles breaks to the nuclear ring's edge (2016) (9)
Repairing subtelomeric DSBs at the nuclear periphery. (2006) (9)
Srs2 helicase prevents the formation of toxic DNA damage during late prophase I of yeast meiosis (2019) (8)
Import of polypeptides into isolated yeast mitochondria. (1983) (8)
Mitotic Expression of Spo13 Alters M-Phase Progression and Nucleolar Localization of Cdc14 in Budding Yeast (2010) (8)
Ribonuclease H(70) is a component of the yeast nuclear scaffold. (1990) (7)
In vitro DNA replication in yeast nuclear extracts. (1999) (7)
Publisher Correction: LifeTime and improving European healthcare through cell-based interceptive medicine (2021) (7)
Selfish DNA and Epigenetic Repression Revisited (2016) (6)
Tracking Individual Chromosomes with Intergrated Arrays of lacop Sites and GFP-laci Repressor: Analyzing Position and Dynamics of Chromosomal Loci in Saccharomyces cerevisiae (2006) (6)
Mechanism of chromatin segregation to the nuclear periphery in C. elegans embryos (2016) (6)
The Sir4 H‐BRCT domain interacts with phospho‐proteins to sequester and repress yeast heterochromatin (2019) (6)
Positions of Potential (2001) (6)
Casein kinase II copurifies with yeast DNA topoisomerase II and reactivates the dephosphorylated enzyme (1999) (5)
Functional interaction between the estrogen receptor and CTF1: analysis of the vitellogenin gene B1 promoter in yeast. (1998) (5)
Assessing import of proteins into mitochondria: an overview. (1983) (5)
Cytoskeleton integrity influences XRCC1 and PCNA dynamics at DNA damage (2021) (5)
The cytochrome b5 tail anchors and stabilizes subdomains of human DNA topoisomerase II alpha in the cytoplasm of retrovirally infected mammalian cells. (1999) (5)
DNA Replication: Pif1 Pulls the Plug on Stalled Replication Forks (2012) (5)
Mutations in the C-terminal domain of topoisomerase II affect meiotic function and interaction with the casein kinase 2β subunit (2004) (5)
Topoisomerase II: its functions and phosphorylation (2004) (4)
A regulatory phosphorylation site on Mec1 controls chromatin occupancy of RNA polymerases during replication stress (2021) (4)
The nucleosome: from wallflower to Queen of the Ball (2001) (4)
Histone degradation in response to DNA damage triggers general chromatin decompaction (2016) (4)
Imported mitochondrial proteins cytochrome b 2 and cytochrome cl are processed in two steps ( mitochondrial biogenesis / protein import / proteolytic processing / in vitro protein synthesis / vectorial processing ) (4)
The study of protein recruitment to laser-induced DNA lesions can be distorted by photoconversion of the DNA binding dye Hoechst (2019) (4)
Epigenetics and disease: pharmaceutical opportunities. Preface. (2011) (4)
9 DNA Replication and Nuclear Architecture (2006) (4)
SETDB1-like MET-2 promotes transcriptional silencing and development independently of its H3K9me-associated catalytic activity (2022) (3)
NUCLEAR ARCHITECTURE: A Genetic Approach (2004) (3)
Once and Only Once (1997) (3)
Leap year: Rare day to highlight rare diseases (2012) (3)
Molecular biology for green recovery—A call for action (2022) (2)
Open questions: Epigenetics and the role of heterochromatin in development (2013) (2)
The shape of heredity (2009) (2)
Tracking individual chromosomes with integrated arrays of Lacop sites and GFP-Laci repressor ( PROT 15 ) (2007) (2)
Functional Aspects of Chromosome Organization: Scaffold Attachment Regions and their Ligands (1992) (2)
A game of musical chairs: Pro- and anti-resection factors compete for TOPBP1 binding after DNA damage (2017) (2)
In vitro DNA replication assays in yeast extracts. (2002) (2)
Analysis of Sir2p domains required for rDNA and telomeric silencing in Saccharomyces cerevisiae. (2000) (2)
Nucleus and gene expression. (2002) (1)
Dimerization of Sir 3 via its C-terminal winged helix domain is essential for heterochromatin formation (2012) (1)
Nutrition and the biology of human ageing: Molecular mechanisms underlying ageing (2013) (1)
Uncoordinated long-patch base excision repair at juxtaposed DNA lesions generates a lethal accumulation of double-strand breaks (2020) (1)
COMMENTARY Regulation of topoisomerase II by phosphorylation: a role for casein kinase II (1993) (1)
Editorial overview: Breaking open the mysteries of nuclear and chromatin organization. (2021) (1)
Faculty Opinions recommendation of Sir2-independent life span extension by calorie restriction in yeast. (2005) (1)
Open questions: Epigenetics and the role of heterochromatin in development (2013) (1)
Long time behaviour of diffusing particles in constrained geometries; application to chromatin motion (2006) (1)
Lessons in chromatin organization and gender equity in research: an interview with Susan Gasser. (2022) (1)
In Vitro-Evolved Peptides Bind Monomeric Actin and Mimic Actin-Binding Protein Thymosin-β4. (2021) (1)
LifeTime and improving European healthcare through cell-based interceptive medicine (2020) (1)
TELOMERE-BINDING ACTIVITY OF FISSION YEAST SCHIZOSACCHAROMYCES POMBE (1999) (1)
Casein kinase 11 phosphorylates the eukaryote-specific C-terminal domain of topoisomerase 11 in vivo (1)
Progress in Drug Research (2013) (0)
Nucleosome Remodeling Complexes Increase Subnuclear Dynamics Of Chromatin In Yeast (2009) (0)
Dynamics of subnuclear chromatin organization during C . elegans development : a role for H 3 K 9 methylation (2012) (0)
HP1beta paper raw/original microscopy images (2015) (0)
LSM2-8 and XRN-2 contribute to the silencing of H3K27me3-marked genes through targeted RNA decay (2020) (0)
Faculty Opinions recommendation of Separable roles for Mec1/ATR in genome maintenance, DNA replication, and checkpoint signaling. (2018) (0)
Supplemental Data A Homotrimer – Heterotrimer Switch in Sir 2 Structure Differentiates rDNA and Telomeric Silencing (2006) (0)
The Sir4 H‐BRCT domain interacts with phospho‐proteins to sequester and repress yeast heterochromatin (2019) (0)
Crystal structure of the Sir4 H-BRCT domain in complex with Ubp10 pT123 peptide (2019) (0)
Imaging functional chromosomes: tethers and dynamics in the yeast nucleus (2004) (0)
Crystal structure of K. lactis Ddc2 N-terminus in complex with S. cerevisiae Rfa1 N-OB domain (2017) (0)
Faculty Opinions recommendation of Nuclear reorganization of mammalian DNA synthesis prior to cell cycle exit. (2004) (0)
Faculty Opinions recommendation of MDC1 is coupled to activated CHK2 in mammalian DNA damage response pathways. (2003) (0)
Crystal structure of K. lactis Ddc2 N-terminus in complex with S. cerevisiae Rfa1 (K45E mutant) N-OB domain (2017) (0)
Author Correction: SETDB1-like MET-2 promotes transcriptional silencing and development independently of its H3K9me-associated catalytic activity (2022) (0)
Faculty Opinions recommendation of Genetic and epigenetic regulation of the FLO gene family generates cell-surface variation in yeast. (2004) (0)
Learning from yeast (2001) (0)
Functional analysis of meiotic recombination checkpoint mediator Mek1 in budding yeast (2017) (0)
Protein-DNA Interaction at Yeast Replication Origins: An ARS Consensus Binding Protein (1992) (0)
Yeast Nuclear Extracts Semiconservative Plasmid Replication in Cdc6-Independent Steps of Cyclin B-Cdk1 Kinase Stimulates ORC- and (2013) (0)
Crystal structure of the Sir4 H-BRCT domain in complex with Esc1 pS1450 peptide (2019) (0)
Crystal structure of S. cerevisiae Rfa1 N-OB domain mutant (K45E) (2016) (0)
[Telomere-binding activity of Schizosaccharomyces pombe yeasts]. (1999) (0)
Preparation and characterization of yeast nuclear extracts for efficient RNA polymerase B ( I Independent transcription in vitro (2005) (0)
Faculty Opinions recommendation of Spatial separation between replisome- and template-induced replication stress signaling. (2018) (0)
Crystal structure of S. cerevisiae Ddc2 N-terminal coiled-coil domain (2017) (0)
Destabilization of the holo-DNA Polδ by loss of Pol32 confers conditional lethality that can be suppressed by stabilizing Pol31-Pol3 interaction (2021) (0)
The 3D Organization of the Nucleus and Inheritance of Epigenetic States (2007) (0)
Spontaneous Formation of Topoisomerase II Multimers in vitro: Effects of Metals, b-Gycerophosphate and Phosphorylation of its C-Terminal Domain (1994) (0)
Epigenetics and diseas (2013) (0)
A Nuclear RNA Degradation Pathway Helps Silence Polycomb/H3K27me3-Marked Loci in Caenorhabditis elegans. (2020) (0)
A Conversation with Susan Gasser. (2020) (0)
Crystal structure of the Sir4 H-BRCT domain (2019) (0)
Faculty Opinions recommendation of Functions of replication protein A as a sensor of R loops and a regulator of rnaseh1. (2018) (0)
Publisher Correction: LifeTime and improving European healthcare through cell-based interceptive medicine (2021) (0)
Sucrose gradient chromatin enrichment for quantitative proteomics analysis in budding yeast (2021) (0)
Table of Contents (1986) (0)
Gene silencing in budding yeast (2016) (0)
Localization to the nuclear pore complex is required for stabilizing CAG repeats (2015) (0)
Nadeshiko revisited (2021) (0)
Challenges and guidelines toward 4D nucleome data and model standards (2018) (0)
In vitro DNA synthesis: Subnuclear targeting of cell‐cycle regulated kinases regulate ORC‐dependent replication in isolated yeast nuclei (1998) (0)
Transcription, Epigenetics and early Development (2021) (0)
Chromatin states and nuclear organization in development — a view from the nuclear lamina (2015) (0)
Making a journal great: an ode to Terri Grodzicker (2023) (0)
Srs2 helicase prevents the formation of toxic DNA damage during late prophase I of yeast meiosis (2019) (0)
The stabilized Pol31–Pol3 interface counteracts Pol32 ablation with differential effects on repair (2021) (0)
Crystal structure of S. cerevisiae Sir3 C-terminal domain (2013) (0)
Faculty Opinions recommendation of Mrc1 and Rad9 cooperate to regulate initiation and elongation of DNA replication in response to DNA damage. (2018) (0)
Active chromatin marks drive spatial sequestration of heterochromatin in C. elegans nuclei (2019) (0)
Copy-Number-and Lamin-Dependent Manner Marks and Are Sequestered at the Nuclear Envelope in a Accumulate Heterochromatic C . elegans Repetitive Transgenes in (2011) (0)
Heterochromatin definition and function. (2023) (0)
The genetics of epigenetics. (1998) (0)
Localization to the Nuclear Pore Complex is Required to Prevent Trinucleotide Repeat Instability (2013) (0)
Unexpected erosion of chromosome cohesion by a mitotic prophase-like pathway in yeast meiosis (2018) (0)
The study of protein recruitment to UV-induced DNA lesions can be distorted by photoconversion of DNA dyes like Hoechst or DAPI. (2019) (0)
Author Correction: SETDB1-like MET-2 promotes transcriptional silencing and development independently of its H3K9me-associated catalytic activity (2022) (0)
Changes in local chromatin structure during homology search (2016) (0)
Involvement of SUMOylation in sister chromatid cohesion during DNA repair (2016) (0)
Crystal structure of the Sir4 H-BRCT domain in complex with Ty5 pS1095 peptide (2019) (0)
Telomeres, the means to many ends (1996) (0)
Editorial Board (2010) (0)

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