Susan Lea
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British microbiologist
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Susan Lea biology Degrees
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Biology
Susan Lea 's Degrees
- Bachelors Microbiology University of Oxford
- PhD Microbiology University of Oxford
Why Is Susan Lea Influential?
(Suggest an Edit or Addition)According to Wikipedia, Susan Mary Lea is a British biologist who serves as chief of the center for structural biology at the National Cancer Institute. Her research investigates host-pathogen interactions and biomolecular pathways. She was elected a Fellow of the Royal Society in 2022.
Susan Lea 's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Refinement of severely incomplete structures with maximum likelihood in BUSTER-TNT. (2004) (716)
- Structure of a major immunogenic site on foot-and-mouth disease virus (1993) (365)
- Neisseria meningitidis recruits factor H using protein mimicry of host carbohydrates (2009) (323)
- The structure and function of a foot‐and‐mouth disease virus–oligosaccharide receptor complex (1999) (301)
- The structure and antigenicity of a type C foot-and-mouth disease virus. (1994) (266)
- Dimerization of complement factor H-related proteins modulates complement activation in vivo (2013) (255)
- A conserved face of the Jagged/Serrate DSL domain is involved in Notch trans-activation and cis-inhibition (2008) (251)
- Structural basis for complement factor H–linked age-related macular degeneration (2007) (202)
- Architecture of the major component of the type III secretion system export apparatus (2012) (195)
- Helical Structure of the Needle of the Type III Secretion System of Shigella flexneri * (2003) (191)
- His-384 Allotypic Variant of Factor H Associated with Age-related Macular Degeneration Has Different Heparin Binding Properties from the Non-disease-associated Form* (2006) (187)
- Notch receptor–ligand binding and activation: Insights from molecular studies (2012) (182)
- Structure of the TatC core of the twin-arginine protein transport system (2012) (167)
- Molecular model of a type III secretion system needle: Implications for host-cell sensing (2006) (166)
- Assembly and regulation of the membrane attack complex based on structures of C5b6 and sC5b9. (2012) (165)
- The Centrosome-Specific Phosphorylation of Cnn by Polo/Plk1 Drives Cnn Scaffold Assembly and Centrosome Maturation (2014) (159)
- Self-chaperoning of the Type III Secretion System Needle Tip Proteins IpaD and BipD* (2006) (157)
- Dissecting the roles of VP0 cleavage and RNA packaging in picornavirus capsid stabilization: the structure of empty capsids of foot-and-mouth disease virus (1997) (153)
- Specific DNA recognition mediated by a type IV pilin (2013) (144)
- What's the point of the type III secretion system needle? (2008) (144)
- Complement factor I in health and disease. (2011) (134)
- Structure of and influence of a tick complement inhibitor on human complement component 5 (2008) (131)
- Defining a protective epitope on factor H binding protein, a key meningococcal virulence factor and vaccine antigen (2013) (124)
- Structural basis for complement factor I control and its disease-associated sequence polymorphisms (2011) (123)
- Molecular Analysis of the Epidermal Growth Factor-like Short Consensus Repeat Domain-mediated Protein-Protein Interactions (2001) (120)
- Complement regulation at the molecular level: the structure of decay-accelerating factor. (2004) (118)
- Antigenic heterogeneity of a foot-and-mouth disease virus serotype in the field is mediated by very limited sequence variation at several antigenic sites (1994) (117)
- Timing is everything: the regulation of type III secretion (2009) (115)
- An atomic resolution model for assembly, architecture, and function of the Dr adhesins. (2004) (113)
- Perturbations in the surface structure of A22 Iraq foot-and-mouth disease virus accompanying coupled changes in host cell specificity and antigenicity. (1996) (109)
- Structural analysis of substrate binding by the TatBC component of the twin-arginine protein transport system (2009) (107)
- Type 9 secretion system structures reveal a new protein transport mechanism (2018) (106)
- Structure of the Core of the Type Three Secretion System Export Apparatus (2018) (106)
- Expression levels of MHC class I molecules are inversely correlated with promiscuity of peptide binding (2015) (106)
- Structure of Foot-and-mouth disease virus serotype A10 61 alone and complexed with oligosaccharide receptor: receptor conservation in the face of antigenic variation. (2005) (101)
- Fringe-mediated extension of O-linked fucose in the ligand-binding region of Notch1 increases binding to mammalian Notch ligands (2014) (96)
- Molecular Dissection of Interactions between Components of the Alternative Pathway of Complement and Decay Accelerating Factor (CD55)* (2005) (96)
- Crystal structures of the CPAP/STIL complex reveal its role in centriole assembly and human microcephaly (2013) (96)
- Structural characterization of an anti-gp120 RNA aptamer that neutralizes R5 strains of HIV-1. (2005) (94)
- Structural basis for therapeutic inhibition of complement C5 (2016) (92)
- The CD46 and Jagged1 interaction is critical for human T helper 1 immunity (2012) (89)
- Molecular footprints reveal the impact of the protective HLA-A*03 allele in hepatitis C virus infection (2011) (88)
- Structures of the stator complex that drives rotation of the bacterial flagellum (2020) (88)
- An Aptamer That Neutralizes R5 Strains of Human Immunodeficiency Virus Type 1 Blocks gp120-CCR5 Interaction (2005) (84)
- Structural Basis for Mitotic Centrosome Assembly in Flies (2017) (79)
- Factor H–Related Protein 5 Interacts with Pentraxin 3 and the Extracellular Matrix and Modulates Complement Activation (2015) (77)
- Structural comparison of two strains of foot-and-mouth disease virus subtype O1 and a laboratory antigenic variant, G67. (1995) (76)
- The characterization of weak protein-protein interactions: evidence from DEER for the trimerization of a von Willebrand Factor A domain in solution. (2006) (75)
- Determination of the Affinity and Kinetic Constants for the Interaction between the Human Virus Echovirus 11 and Its Cellular Receptor, CD55* (1998) (74)
- Corrigendum: Three-dimensional reconstruction of the Shigella T3SS transmembrane regions reveals 12-fold symmetry and novel features throughout (2009) (71)
- A complex iron-calcium cofactor catalyzing phosphotransfer chemistry (2014) (69)
- Semaphorin-7A Is an Erythrocyte Receptor for P. falciparum Merozoite-Specific TRAP Homolog, MTRAP (2012) (68)
- TatBC, TatB, and TatC form structurally autonomous units within the twin arginine protein transport system of Escherichia coli (2007) (67)
- Factor I autoantibodies in patients with atypical hemolytic uremic syndrome: disease-associated or an epiphenomenon? (2012) (65)
- A novel fold for the factor H–binding protein BbCRASP-1 of Borrelia burgdorferi (2005) (64)
- Structural and Functional Characterization of a Novel T Cell Receptor Co-regulatory Protein Complex, CD97-CD55* (2007) (63)
- The Escherichia coli Cell Division Protein and Model Tat Substrate SufI (FtsP) Localizes to the Septal Ring and Has a Multicopper Oxidase-Like Structure (2009) (62)
- Crystal structure of Spa40, the specificity switch for the Shigella flexneri type III secretion system (2008) (60)
- High Resolution Studies of the Afa/Dr Adhesin DraE and Its Interaction with Chloramphenicol* (2004) (60)
- Structural and Functional Characterization of the Bacterial Type III Secretion Export Apparatus (2016) (59)
- Design and Evaluation of Meningococcal Vaccines through Structure-Based Modification of Host and Pathogen Molecules (2012) (57)
- The Structure of OMCI, a Novel Lipocalin Inhibitor of the Complement System (2007) (56)
- Determination of the Structure of a Decay Accelerating Factor-Binding Clinical Isolate of Echovirus 11 Allows Mapping of Mutants with Altered Receptor Requirements for Infection (2002) (56)
- Structures of CD6 and Its Ligand CD166 Give Insight into Their Interaction (2015) (55)
- 3D reconstruction of the Shigella T3SS transmembrane regions reveals 12-fold symmetry and novel features throughout (2009) (55)
- Structural Basis for Recognition of the Pore-Forming Toxin Intermedilysin by Human Complement Receptor CD59 (2013) (54)
- EspM2 is a RhoA guanine nucleotide exchange factor (2010) (54)
- Competition between antagonistic complement factors for a single protein on N. meningitidis rules disease susceptibility (2014) (54)
- The homo-oligomerisation of both Sas-6 and Ana2 is required for efficient centriole assembly in flies (2015) (51)
- Characterisation of Shigella Spa33 and Thermotoga FliM/N reveals a new model for C‐ring assembly in T3SS (2015) (51)
- Intersubunit allosteric communication mediated by a conserved loop in the MCM helicase (2009) (51)
- Mapping CD55 Function (2003) (51)
- Structures of CD200/CD200 Receptor Family and Implications for Topology, Regulation, and Evolution (2013) (50)
- Building a secreting nanomachine: a structural overview of the T3SS☆ (2014) (50)
- Structural Analysis Uncovers Lipid-Binding Properties of Notch Ligands (2013) (49)
- Functional Analysis of the Interdependence between DNA Uptake Sequence and Its Cognate ComP Receptor during Natural Transformation in Neisseria Species (2013) (48)
- Crystal Structure of the Bacillus subtilis Phosphodiesterase PhoD Reveals an Iron and Calcium-containing Active Site♦ (2014) (47)
- Biological activity, membrane‐targeting modification, and crystallization of soluble human decay accelerating factor expressed in E. coli (2004) (47)
- Helical packing of needles from functionally altered Shigella type III secretion systems. (2005) (43)
- Symmetry mismatch in the MS-ring of the bacterial flagellar rotor explains structural coordination of secretion and rotation (2020) (41)
- Rev Binds Specifically to a Purine Loop in the SL1 Region of the HIV-1 Leader RNA* (2003) (40)
- FHR-1 Binds to C-Reactive Protein and Enhances Rather than Inhibits Complement Activation (2017) (40)
- Interactions of CD55 with non-complement ligands. (2001) (38)
- The Structure of an Injectisome Export Gate Demonstrates Conservation of Architecture in the Core Export Gate between Flagellar and Virulence Type III Secretion Systems (2019) (38)
- Structures of the Shigella flexneri Type 3 Secretion System Protein MxiC Reveal Conformational Variability Amongst Homologues (2008) (38)
- The substrate specificity switch FlhB assembles onto the export gate to regulate type three secretion (2020) (38)
- Crystal Structure and Functional Characterization of the Complement Regulator Mannose-binding Lectin (MBL)/Ficolin-associated Protein-1 (MAP-1)* (2012) (37)
- Two cross‐reactive monoclonal antibodies recognize overlapping epitopes on Neisseria meningitidis factor H binding protein but have different functional properties (2014) (36)
- Structural and functional dissection of the interplay between lipid and Notch binding by human Notch ligands (2017) (36)
- Decay-Accelerating Factor Must Bind Both Components of the Complement Alternative Pathway C3 Convertase to Mediate Efficient Decay1 (2007) (36)
- Molecular structure of the intact bacterial flagellar basal body (2020) (35)
- Bifunctional Lipocalin Ameliorates Murine Immune Complex-induced Acute Lung Injury (2013) (35)
- The Salmonella Type III Secretion System Inner Rod Protein PrgJ Is Partially Folded* (2012) (35)
- Polymorphisms in the Human Inhibitory Signal-regulatory Protein α Do Not Affect Binding to Its Ligand CD47* (2014) (35)
- Distinct Binding and Immunogenic Properties of the Gonococcal Homologue of Meningococcal Factor H Binding Protein (2013) (34)
- Molecular Basis for Jagged-1/Serrate Ligand Recognition by the Notch Receptor* (2013) (33)
- The Structure of Echovirus Type 12 Bound to a Two-domain Fragment of Its Cellular Attachment Protein Decay-accelerating Factor (CD 55)* (2004) (33)
- Mechanism for the Hydrolysis of a Sulfur-Sulfur Bond Based on the Crystal Structure of the Thiosulfohydrolase SoxB* (2009) (32)
- Structural and Functional Studies on the N-terminal Domain of the Shigella Type III Secretion Protein MxiG (2011) (31)
- Structural and Functional Insights into the Interaction of Echoviruses and Decay-accelerating Factor* (2006) (31)
- Molecular basis for redox control by the human cystine/glutamate antiporter system xc− (2021) (31)
- SepL Resembles an Aberrant Effector in Binding to a Class 1 Type III Secretion Chaperone and Carrying an N-Terminal Secretion Signal (2010) (30)
- Structure and mechanism of the proton-driven motor that powers Type 9 secretion and gliding motility (2020) (30)
- Structure of Human Complement C8, a Precursor to Membrane Attack (2011) (30)
- The type III needle and the damage done. (2005) (30)
- Human complement factor I glycosylation: structural and functional characterisation of the N-linked oligosaccharides. (2006) (28)
- SAS-6 oligomerization: the key to the centriole? (2011) (27)
- Structural biology of Tat protein transport. (2014) (26)
- High-resolution structures of bacterially expressed soluble human CD59. (2007) (26)
- A Comparative Structure/Function Analysis of Two Type IV Pilin DNA Receptors Defines a Novel Mode of DNA Binding (2016) (26)
- Nonfunctional Variant 3 Factor H Binding Proteins as Meningococcal Vaccine Candidates (2013) (25)
- Hydrophilic Domain II of Escherichia coli Dr Fimbriae Facilitates Cell Invasion (2005) (24)
- Mechanism of lipid droplet formation by the yeast Sei1/Ldb16 Seipin complex (2021) (23)
- Shigella flexneri Spa15 Crystal Structure Verified in Solution by Double Electron Electron Resonance (2011) (23)
- Structural basis for specificity and promiscuity in a carrier protein/enzyme system from the sulfur cycle (2015) (23)
- Assembly and Regulation of the Membrane Attack Complex Based on Structures of C 5 b 6 and sC 5 b 9 (2012) (23)
- Mutational analyses of the BbCRASP-1 protein of Borrelia burgdorferi identify residues relevant for the architecture and binding of host complement regulators FHL-1 and factor H. (2009) (23)
- The CD 46-Jagged 1 interaction is critical for human TH 1 immunity (2012) (23)
- Non-Linear and Flexible Regions of the Human Notch1 Extracellular Domain Revealed by High-Resolution Structural Studies (2016) (23)
- Structural basis of antifolate recognition and transport by PCFT (2021) (22)
- Expression, purification, crystallization and preliminary crystallographic analysis of MxiH, a subunit of the Shigella flexneri type III secretion system needle (2006) (22)
- A signal sequence suppressor mutant that stabilizes an assembled state of the twin arginine translocase (2017) (22)
- Crystallization and preliminary X-ray analysis of three serotypes of foot-and-mouth disease virus. (1992) (21)
- Structure-based design of chimeric antigens for multivalent protein vaccines (2018) (21)
- Structure-function mapping of BbCRASP-1, the key complement factor H and FHL-1 binding protein of Borrelia burgdorferi. (2006) (20)
- Identification and characterization of the ‘missing’ terminal enzyme for siroheme biosynthesis in α-proteobacteria (2014) (20)
- Mechanism of Thiosulfate Oxidation in the SoxA Family of Cysteine-ligated Cytochromes (2015) (20)
- SIMPLE 3.0. Stream single-particle cryo-EM analysis in real time. (2020) (19)
- An inhibitor of complement C5 provides structural insights into activation (2019) (19)
- Type 9 secretion system structures reveal a new protein transport mechanism (2018) (18)
- Analysis of antigenic surfaces of proteins (1995) (17)
- Expression, purification, cocrystallization and preliminary crystallographic analysis of sucrose octasulfate/human complement regulator factor H SCRs 6-8. (2007) (17)
- Cryo-EM structure of PepT2 reveals structural basis for proton-coupled peptide and prodrug transport in mammals (2021) (16)
- Cryo-EM structure and resistance landscape of M. tuberculosis MmpL3: An emergent therapeutic target (2021) (14)
- Further structural insights into the binding of complement factor H by complement regulator-acquiring surface protein 1 (CspA) of Borrelia burgdorferi (2013) (14)
- A key centriole assembly interaction interface between human PLK4 and STIL appears to not be conserved in flies (2017) (13)
- On the state of crystallography at the dawn of the electron microscopy revolution (2017) (13)
- ErpC, a member of the complement regulator-acquiring family of surface proteins from Borrelia burgdorferi, possesses an architecture previously unseen in this protein family (2013) (13)
- Structural basis of cholesterol binding by a novel clade of dendritic cell modulators from ticks (2017) (12)
- Model of the equine rhinitis A virus capsid: identification of a major neutralizing immunogenic site. (2003) (11)
- Structural Insights into Notch Receptor-Ligand Interactions. (2018) (11)
- Structures of SALSA/DMBT1 SRCR domains reveal the conserved ligand-binding mechanism of the ancient SRCR fold (2019) (11)
- Nonameric structures of the cytoplasmic domain of FlhA and SctV in the context of the full-length protein (2020) (11)
- Expression, limited proteolysis and preliminary crystallographic analysis of IpaD, a component of the Shigella flexneri type III secretion system (2006) (11)
- Tetartohedral twinning could happen to you too (2012) (11)
- Complement factor H: using atomic resolution structure to illuminate disease mechanisms. (2008) (10)
- Interactions of decay-accelerating factor (DAF) with haemagglutinating human enteroviruses: utilizing variation in primate DAF to map virus binding sites. (2004) (9)
- Structure of a proton-powered molecular motor that drives protein transport and gliding motility (2020) (9)
- Structures of the rat complement regulator CrrY (2011) (9)
- FOOT-AND-MOUTH DISEASE VIRUS/ OLIGOSACCHARIDE RECEPTOR COMPLEX. (1999) (9)
- Characterizing sequence variation in the VP1 capsid proteins of foot and mouth disease virus (serotype 0) with respect to virion structure (1998) (9)
- Crystallization and preliminary X-ray diffraction analysis of a biologically active fragment of CD55. (1999) (9)
- Putting the structure into complement. (2012) (9)
- The structure of an immunodominant loop on foot and mouth disease virus, serotype O1, determined under reducing conditions. (1994) (9)
- Crystallization and preliminary crystallographic analysis of BbCRASP-1, a complement regulator-acquiring surface protein of Borrelia burgdorferi. (2004) (9)
- Structures of the stator complex that drives rotation of the bacterial flagellum (2020) (8)
- Expression, purification, crystallization and preliminary crystallographic analysis of BipD, a component of the Burkholderia pseudomallei type III secretion system (2006) (8)
- Huntingtin structure is orchestrated by HAP40 and shows a polyglutamine expansion-specific interaction with exon 1 (2021) (8)
- SIMPLE 3.0. Stream single-particle cryo-EM analysis in real time (2020) (7)
- Structural control for the coordinated assembly into functional pathogenic type-3 secretion systems (2019) (7)
- Crystallization and preliminary X-ray diffraction analysis of three EGF domains of EMR2, a 7TM immune-system molecule. (2004) (7)
- A structural study of the interaction between the Dr haemagglutinin DraE and derivatives of chloramphenicol (2009) (6)
- Different modes of variation for each BG lineage suggest different functions (2016) (6)
- Autoantibodies to CD59, CD55, CD46 or CD35 are not associated with atypical haemolytic uraemic syndrome (aHUS). (2015) (6)
- The DNA transporter ComEC has metal‐dependent nuclease activity that is important for natural transformation (2021) (5)
- With phases: how two wrongs can sometimes make a right (2010) (5)
- Deconvolution of fully overlapped reflections from crystals of foot-and-mouth disease virus O1 G67. (1995) (5)
- Structure and function of a family of tick-derived complement inhibitors targeting properdin (2022) (5)
- Structure of the core of the type III secretion system export apparatus (2018) (5)
- The flagellar substrate specificity switch protein FlhB assembles onto the extra-membrane export gate to regulate type three secretion (2019) (5)
- The S. Typhi effector StoD is an E3/E4 ubiquitin ligase which binds K48- and K63-linked diubiquitin (2019) (5)
- ADDITIONS AND CORRECTIONS (2013) (4)
- Correction: Design and Evaluation of Meningococcal Vaccines through Structure-Based Modification of Host and Pathogen Molecules (2013) (4)
- An inhibitor of complement C5 provides structural insights into activation. (2020) (4)
- Structures of the Type IX Secretion/Gliding Motility Motor from across the Phylum Bacteroidetes (2022) (4)
- Structure of the bacterial flagellar rotor MS-ring: a minimum inventory/maximum diversity system (2019) (4)
- Foot-and Mouth Disease Virus Serotype A1061 (2005) (3)
- Author Correction: Structure of the core of the type III secretion system export apparatus (2018) (3)
- Maintenance of the Shigella sonnei Virulence Plasmid Is Dependent on Its Repertoire and Amino Acid Sequence of Toxin-Antitoxin Systems (2022) (3)
- Symmetry mismatch in the MS-ring of the bacterial flagellar rotor explains the structural coordination of secretion and rotation (2020) (3)
- Erratum: Structure of and influence of a tick complement inhibitor on human complement component 5 (2008) (3)
- Antigenic Heterogeneity ofaFoot-and-Mouth Disease Virus Serotype intheField IsMediated byVeryLimited Sequence Variation atSeveral Antigenic Sites (1994) (3)
- Molecular Model of a Type III Secretion System Needle (2007) (2)
- The interaction between factor H and Neisseria meningitidis (2009) (2)
- Molecular Basis for Bordetella pertussis Interference with Complement, Coagulation, Fibrinolytic, and Contact Activation Systems: the Cryo-EM Structure of the Vag8-C1 Inhibitor Complex (2021) (2)
- The substrate specificity switch FlhB assembles onto the export gate to regulate type three secretion (2020) (2)
- Structure of human complement C5 complexed with tick inhibitors OmCI, RaCI1 and CirpT1 (2020) (2)
- Crystal structure of the cytoplasmic domain of Spa40, the specificity switch for the Shigella flexneri Type III Secretion System (2008) (2)
- High resolution cryoEM structure of huntingtin in complex with HAP40 (2020) (2)
- Investigating the structure of the factor B vWF-A domain/CD55 protein–protein complex using DEER spectroscopy: successes and pitfalls (2013) (2)
- The Structure of Foot and Mouth Disease Virus Serotype SAT1 (2010) (2)
- Structural findings in complement factor H-related proteins unravel the pathogenesis of C3 glomerulopathy (2012) (2)
- Pseudomonas fluorescens PhoX in complex with vanadate, a transition state analogue (2012) (2)
- Japanin from Rhipicephalus appendiculatus bound to cholesterol: Tetragonal crystal form (2014) (1)
- 1Modelling the complex between CD55 and Factor B using electron paramagnetic resonance (2007) (1)
- Investigating host specificity of Neisseria meningitidis (2011) (1)
- Erratum: Helical structure of the needle of the type III secretion system of Shigella flexneri (Journal of Biological Chemistry (2003) 278 (17103-17107)) (2003) (1)
- Towards the crystal structure of intact Human Complement Factor I (2009) (1)
- Human complement factor I (2011) (1)
- Autoantibodies to CD59, CD55, CD46 and CD35 are not associated with aHUS (2014) (1)
- Factor I autoantibodies are associated with atypical haemolytic uraemic syndrome (2010) (1)
- The structure of a type C foot-and-mouth disease virus at 3.5 Å (1993) (1)
- Structure of tick complement inhibitor CirpT1 complexed with macroglobubulin domain 4 of human complement C5 (2020) (1)
- Structural insights into a novel properdin-binding tick inhibitor from Rhipicephalus pulchellus (2018) (1)
- Structural studies of human CD59 and its ligands (2007) (1)
- HAP40 orchestrates huntingtin structure for differential interaction with polyglutamine expanded exon 1 (2021) (1)
- Targeting properdin - Structure and function of a novel family of tick-derived complement inhibitors (2021) (1)
- Structure of GldLM, the proton-powered motor that drives protein transport and gliding motility (2020) (1)
- The conserved C2 phospholipid‐binding domain in Delta contributes to robust Notch signalling (2021) (1)
- Methylated Shigella flexneri MxiC (2008) (0)
- Complex between the Leucine Zipper (LZ) and Centrosomin-motif 2 (CM2) domains of Drosophila melanogaster Centrosomin (Cnn) - L535E mutant form (2017) (0)
- Studies of the Type IV Pilus of Neisseria meningitidis (2014) (0)
- Human Notch1 EGF domains 11-13 mutant GlcNAc-fucose disaccharide modified at T466 (2014) (0)
- The assembly of c4b-binding protein via its oligomerisation domain (2011) (0)
- SALSA / DMBT1 / GP340 SRCR domain 8 soaked in calcium and magnesium (2020) (0)
- Author response: Competition between antagonistic complement factors for a single protein on N. meningitidis rules disease susceptibility (2014) (0)
- Salmonella export gate and rod refined in focussed C1 map (2021) (0)
- Structure of the complex of the extracellular portions of mouse CD200R and mouse CD200 (2013) (0)
- Building the Drosophila centriole: a structural investigation of the centriolar Proteins SAS-6, SAS-4 and Ana2 (2014) (0)
- OMCI in complex with palmitoleic acid (2012) (0)
- Structural analysis of the soluble C5b-9 complex using cryo-electron microscopy (2007) (0)
- Chicken TAP genes are polymorphic and co-evolve with the dominantly-expressed class I gene (2012) (0)
- Solution structure of the N-terminal domain of the Shigella type III secretion protein MxiG (2011) (0)
- Structure of the N-terminal four domains of the complement regulator Rat Crry (2011) (0)
- Structure of Drosophila Serrate C2-DSL-EGF1-EGF2 (2021) (0)
- DraE Adhesin in complex with Chloramphenicol Succinate (2008) (0)
- Extracellular SRCR domains of human CD6 (2015) (0)
- Surface plasmon resonance analysis of decay acceleration in the alternative pathway of complement (2007) (0)
- Structural and functional insights into properdin of the complement alternative pathway (2016) (0)
- EGF Domains 1,2,5 of human EMR2, a 7-TM immune system molecule, in complex with strontium. (2006) (0)
- From Structure to Function of a Complement Regulator: Decay-Accelerating Factor (CD55) (2005) (0)
- Structures of human CD6 and its ligand, CD166, reveal insights into a unique interaction (2013) (0)
- Structural basis of cholesterol binding by a novel clade of dendritic cell modulators from ticks (2017) (0)
- Structure of a fHbp(V1.1):PorA(P1.16) chimera. Fusion at fHbp position 309. (2018) (0)
- High resolution structure of human CD59 (2007) (0)
- Structural views of complement protein interactions (2004) (0)
- Towards the crystal structure of human complement factor I (2006) (0)
- SeMet substituted Shigella Flexneri Ipad (2006) (0)
- Structural studies on foot-and-mouth disease virus (1993) (0)
- The complement inhibitor OmCI in complex with ricinoleic acid (2007) (0)
- Structure of Drosophila C2-DSL-EGF1 (2021) (0)
- Structural snapshots of the Type 9 protein translocon Plug-complex (2018) (0)
- Specificity and mechanism of assembly of C4b binding protein (2012) (0)
- Cryo EM structure of System XC- in complex with glutamate (2021) (0)
- Human CD55 domains 3 & 4 (2003) (0)
- Interactions between factor H and Neisseria meningitidis (2007) (0)
- Structural studies of CD55 interactions with pathogen-derived ligands (2004) (0)
- Crystallisation and preliminary characterisation of crystals of complement component proteins (2004) (0)
- Factor H-related protein 1 ( FHR-1 ) binds to C-reactive protein and enhances 5 rather than inhibits complement activation 6 7 (2017) (0)
- Delivering a toxic metal to the active site of urease (2023) (0)
- Structure of a disulfide locked mutant of Intermedilysin with human CD59 (2013) (0)
- Bifunctional lipocalin inhibitor of C5 and leukotriene B4 is protective in experimental immune complex alveolitis (2010) (0)
- Further insights into modulation of complement activation by the factor H-related family of proteins (2013) (0)
- Pseudomonas fluorescens PhoX in complex with phosphate (2013) (0)
- Termus thermophilus Sulfate thiohydrolase SoxB in complex with thiosulfate (2009) (0)
- Nonameric cytoplasmic domain of FlhA from Vibrio parahaemolyticus (2021) (0)
- A FliPQR complex forms the core of the Salmonella type III secretion system export apparatus. (2018) (0)
- Kinetic analysis of the interaction between the complement regulators CD46 and CD55 and components of the alternative pathway of complement (2004) (0)
- Cryo-EM structure of the proton coupled folate transporter at pH 6.0 bound to pemetrexed (2021) (0)
- Structural studies of CD55 interactions with human proteins (2004) (0)
- DraE Adhesin in complex with Chloramphenicol Succinate (monoclinic form) (2009) (0)
- Structure of the C-terminal barrel of Neisseria meningitidis FHbp Variant 2 (2012) (0)
- DraE Adhesin in complex with Chloramphenicol Succinate (trigonal form) (2008) (0)
- Cryo-EM structure of the outward open proton coupled folate transporter at pH 7.5 (2021) (0)
- PB3 Domain of Human PLK4 (apo) (2017) (0)
- Crystal structure of the oligomerisation domain of C4b-binding protein from Gallus gallus (2012) (0)
- Structure of the RBM3/collar region of the Salmonella flagella MS-ring protein FliF with 33-fold symmetry applied (2020) (0)
- SALSA / DMBT1 / GP340 SRCR domain 8 (2020) (0)
- Central Coiled-Coil Domain of Human STIL (2017) (0)
- AfaE-3 adhesin from Escherichia Coli (2004) (0)
- human Notch 1, EGF 4-7 (2016) (0)
- Solution structure of the engineered protein Afae-dsc (2005) (0)
- Determining the structure of the complex between vWF-A of factor B and CD55 (2008) (0)
- A novel inhibitor of complement C5 provides structural insights into activation (2019) (0)
- Human Jagged-1, domains DSL and EGFs1-3 (2008) (0)
- Complex of E. Coli DraE adhesin with Chloramphenicol (2004) (0)
- The cryo-EM structure of the Vag8-C1 inhibitor complex (2021) (0)
- SALSA / DMBT1 / GP340 SRCR domain 1 (2020) (0)
- Jagged1 is a CD46 ligand and disturbance in CD46/Jagged 1 interaction leads to abnormal Th1 function and infections in humans (2012) (0)
- Core components of bacterial protein secretion systems revealed at high resolution by cryo-electron microscopy (2018) (0)
- PNAS Plus Significance Statements (2015) (0)
- Structure of Drosophila Notch EGF domains 11-13 (2021) (0)
- Centrosomin-motif 2 (CM2) domain of Drosophila melanogaster Centrosomin (Cnn) (2017) (0)
- Structure of the extracellular portion of mouse CD200RLa (2013) (0)
- Cryo-EM structure of the mycolic acid transporter MmpL3 from M. tuberculosis (2021) (0)
- Structural design of a chimeric multivalent Neisseria meningitidis vaccine (2018) (0)
- 33mer structure of the Salmonella flagella MS-ring protein FliF (2020) (0)
- Metalloproteins: structure and function (2014) (0)
- Structure of the core Shigella flexneri type III secretion system export gate complex SctRST (Spa24/Spa9/Spa29). (2019) (0)
- BipD of Burkholderia Pseudomallei (2006) (0)
- Structure of the RBM2 inner ring of Salmonella flagella MS-ring protein FliF with 22-fold symmetry applied (2020) (0)
- Structural analysis of complement proteins: a brief comparison of available approaches (2007) (0)
- Termus thermophilus Sulfate thiohydrolase SoxB (2009) (0)
- Improved map of the FliPQR complex that forms the core of the Salmonella type III secretion system export apparatus. (2019) (0)
- Deconvolution of data from intimately twinned crystals of FMDV (1993) (0)
- Shigella Flexneri IpaD (2006) (0)
- Crystal structure of the disulfide-linked complex of the thiosulfodyrolase SoxB with the carrier-protein SoxYZ from Thermus thermophilus (2015) (0)
- Structural insights into complement function via studies of pathogen derived proteins (2007) (0)
- Characterisation of the CCP7 heparin-binding site in human complement factor H: Functional variation in AMD-associated allelic variant (2007) (0)
- Molecular basis for B. pertussis interference with complement, coagulation, fibrinolytic and contact activation systems: The cryo-EM structure of the Vag8-C1 inhibitor complex (2020) (0)
- Salmonella flagellar basal body assembly intermediate - P ring alone structure (2021) (0)
- Structure of the RBM2inner region of the Salmonella flagella MS-ring protein FliF with 21-fold symmetry applied. (2020) (0)
- Crystallization and preliminary X-ray diffraction analysis of a biologically active fragment of CD55 (1999) (0)
- Author Correction: Structures of the stator complex that drives rotation of the bacterial flagellum (2020) (0)
- Expanding the Huntington’s disease research toolbox; validated subdomain protein constructs for biochemical and structural investigation of huntingtin (2022) (0)
- OMCI in complex with leukotriene B4 (2012) (0)
- Salmonella LP ring 26 mer refined in C26 map (2021) (0)
- SALSA-Step by step (2017) (0)
- The crystal structure of rat complement receptor 1-related protein Y (CrrY) helps dissecting decay-acceleration and fI-cofactor activities (2008) (0)
- Structure of the flagellar MotAB stator complex from Bacillus subtilis (2020) (0)
- Interactions of CD55 with non-C ligands (2002) (0)
- Human Notch-1 EGFs 11-13 (2008) (0)
- Single-particle electron microscopy reconstruction of the structure of complement component 8 (C8) at 23 angstrom resolution (2008) (0)
- Foot-and-Mouth Disease virus serotype A1061 complexed with oligosaccharide receptor. (2005) (0)
- Structure of a Proton-Powered Motor that Drives Protein Transport and Gliding Motility (2020) (0)
- Crystal structure of C5b6 (2012) (0)
- Structural snapshots of the Type 9 protein translocon (2018) (0)
- Abstract C128: Development of therapeutic anti-Jagged1 monoclonal antibodies (2015) (0)
- Author Correction: Structure of the core of the type III secretion system export apparatus (2018) (0)
- Structure of the flagellar MotAB stator complex from Clostridium sporogenes (2020) (0)
- Ternary complex of human Complement C5 with Ornithodoros moubata OmCI and Rhipicephalus appendiculatus RaCI1 (2016) (0)
- Structure of the FliPQR complex from the flagellar type 3 secretion system of Pseudomonas savastanoi. (2020) (0)
- DraE adhesin from Escherichia Coli (2004) (0)
- Termus thermophilus Sulfate thiohydrolase SoxB in complex with glycerol (2009) (0)
- Structure of the virion and empty capsids of A22 Iraq 24/67 foot-and-mouth disease virus (1993) (0)
- Cryo-EM structure of yeast Sei1 with locking helix deletion (2021) (0)
- Structural Studies of the Inner Membrane Ring of the Bacterial Type III Secretion System (2012) (0)
- Structure of domains 6 and 7 of the mouse complement regulator Factor H (2012) (0)
- Structure of VapBC from Shigella sonnei (2020) (0)
- Cryo EM structure of System XC (2021) (0)
- Crystallographic studies of human complement factor I (2007) (0)
- Complex between the Leucine Zipper (LZ) and Centrosomin-motif 2 (CM2) domains of Drosophila melanogaster Centrosomin (Cnn) (2017) (0)
- Structure-based design of chimeric antigens for multivalent protein vaccines (2018) (0)
- MTSL spin-labelled Shigella Flexneri Spa15 (2010) (0)
- Structural studies on decay accelerating factor and other complement regulators (2001) (0)
- Ternary complex of human Complement C5 with Ornithodoros moubata OmCI and Dermacentor andersoni RaCI3. (2016) (0)
- Human Notch1 EGF domains 11-13 mutant fucosylated at T466 (2014) (0)
- SAS-4 (dCPAP) TCP domain in complex with a Proline Rich Motif of Ana2 (dSTIL) of Drosophila Melanogaster (2013) (0)
- 34mer structure of the Salmonella flagella MS-ring protein FliF (2020) (0)
- Structure of the core of the flagellar export apparatus from Vibrio mimicus, the FliPQR-FlhB complex. (2020) (0)
- Complex Of Echovirus Type 12 With Domains 1, 2, 3 and 4 Of Its Receptor Decay Accelerating Factor (Cd55) By Cryo Electron Microscopy At 16 A (2004) (0)
- PB3 Domain of Drosophila melanogaster PLK4 (Sak) (2017) (0)
- STRUCTURE OF THE TWO C-TERMINAL DOMAINS OF COMPLEMENT FACTOR H RELATED PROTEIN 2 (2013) (0)
- The structure of CbiX, the terminal Enzyme for Biosynthesis of Siroheme in Denitrifying Bacteria (2014) (0)
- Central Coiled-Coil Domain (CCCD) of Drosophila melanogaster Ana2. A natural, parallel, tetrameric coiled-coil bundle. (2015) (0)
- PB3 Domain of Human PLK4 in Complex with Coiled-Coil Domain of STIL (2017) (0)
- Structure of the C-terminal SpoA domain of Shigella flexneri Spa33 (2015) (0)
- The novel Jagged1/CD46 interaction: A prime target for immune modulation by viruses? (2012) (0)
- Ternary complex of human Complement C5 with Ornithodoros moubata OmCI and Rhipicephalus microplus RaCI2 (2016) (0)
- Structure of a fHbp(V1.4):PorA(P1.16) chimera. Fusion at fHbp position 151. (2018) (0)
- Complementing Pathogens or Structural Insights into Pathogen Evasion of the Complement System (2005) (0)
- protein 5 (CFHR5) interacts with pentraxin 3 and the extracellular matrix and modulates complement activation (2017) (0)
- Immune Complex-induced Acute Lung Bifunctional Lipocalin Ameliorates Murine Immunology : (2013) (0)
- Decision letter: The flagellar motor of Vibrio alginolyticus undergoes major structural remodeling during rotational switching (2020) (0)
- Structure of the RBM3/collar region of the Salmonella flagella MS-ring protein FliF with 32-fold symmetry applied (2020) (0)
- Decay accelerating factor (CD55): the structure of an intact human complement regulator. (2004) (0)
- The role of toxin:antitoxin systems and insertion sequences in the loss of virulence in Shigella sonnei (2020) (0)
- Structure of PhoD (2012) (0)
- MBL-Ficolin Associated Protein-1, MAP-1 aka MAP44 (2012) (0)
- Interactions of Neisseria meningitidis with the human immune system (2015) (0)
- SeMet derivative of BbCRASP-1 from Borrelia Burgdorferi (2005) (0)
- Complex between the Leucine Zipper (LZ, residues 490-567) and Centrosomin-motif 2 (CM2) domains of Drosophila melanogaster Centrosomin (Cnn) (2017) (0)
- Structure of the Yeast Seipin Reveals Determinants for Lipid Droplet Biogenesis (2021) (0)
- StoD is a novel Salmonella Typhi type III secretion system E3 ubiquitin ligase effector (2019) (0)
- COMPLEX OF A B21 CHICKEN MHC CLASS I MOLECULE AND A 10MER CHICKEN PEPTIDE (2015) (0)
- Structural insights into the control of type three secretion (2011) (0)
- Human Notch-2 EGF11-13 (2017) (0)
- Structure of the RBM3/collar region of the Salmonella flagella MS-ring protein FliF with 34-fold symmetry applied (2020) (0)
- Crystallographic studies of decay-accelerating factor (CD55) (2002) (0)
- Crystal structure of the thiosulfate dehydrogenase TsdA in complex with thiosulfate (2015) (0)
- Crystal structure of Human Complement Factor H, SCR domains 6-8 (H402 risk variant), in complex with ligand. (2007) (0)
- Two membrane distal IgSF domains of CD166 (2015) (0)
- THE VACCINE ANTIGEN FACTOR H BINDING PROTEIN FROM NEISSERIA MENINGITIDIS CAN BE MODIFIED TO REDUCE BINDING TO FACTOR H WITH NO CHANGE IN IMMUNOGENICITY (2010) (0)
- Human Notch1 EGF domains 11-13 mutant T466A (2014) (0)
- The complement regulator-acquiring surface protein (CRASP)-1 of Borrelia burgdorferi: Sequence and binding characteristics among CRASP-1 homologs and mapping of the FHL-1 and Factor H binding site within CRASP-1 (2004) (0)
- SufI Protein from Escherichia Coli (2008) (0)
- Delta C2 Domain β1-2 loop contributes to robust Notch signalling (2021) (0)
- Structural perspectives on bacterial secretion machines (2014) (0)
- Salmonella FliF ring (34mer) in intact basal body - C1 (2021) (0)
- Structural Design of Chimeric Antigens for Multivalent Protein Vaccines (2017) (0)
- Cryo-EM structure of yeast Sei1 (2021) (0)
- Cryo-EM structure of the mammalian peptide transporter PepT2 (2021) (0)
- N-terminal fragment of Drosophila melanogaster Sas-6 (F143D), dimerised via the coiled-coil domain. (2015) (0)
- Structure of the FliPQR complex from the flagellar type 3 secretion system of Vibrio mimicus. (2020) (0)
- Structure and function of a family of tick-derived complement inhibitors targeting properdin (2022) (0)
- Engineering of factor H binding protein, a key vaccine antigen for the prevention of meningococcal disease (2014) (0)
- Structure and function of complement inhibitors from ticks (2015) (0)
- SeMet AfaE-3 adhesin from Escherichia Coli (2004) (0)
- Structure of a complex between CCPs 6 and 7 of Human Complement Factor H and Neisseria meningitidis FHbp Variant 1 E283AE304A mutant (2012) (0)
- Structural insights into the assembly of C4b-binding protein via its oligomerisation domain (2011) (0)
- BbCRASP-1 from Borrelia Burgdorferi (2005) (0)
- Pseudomonas fluorescens PhoX in complex with the substrate analogue AppCp (2012) (0)
- Structure of a fHbp(V1.4):PorA(P1.16) chimera. Fusion at fHbp position 309. (2018) (0)
- Structure of Neisseria meningitidis Major Pillin (2016) (0)
- Towards a structural basis for complement factor H linked age-related macular degeneration (2007) (0)
- Structural and functional characteristics of MBL/Ficolin-associated Protein-1 (MAP-1) (2011) (0)
- DraE Adhesin in complex with Bromamphenicol (2008) (0)
- Binding characteristics and immunogenicity of modified factor H binding protein from Neisseria meningitidis (2010) (0)
- Dissecting the Factor H binding site of Neisseria meningitidis Factor H binding protein (2011) (0)
- Japanin from Rhipicephalus appendiculatus bound to cholesterol: Orthorhombic crystal form (2014) (0)
- Characterisation of a heparin binding domain in complement factor H (2006) (0)
- Decay Pathway C 3 Convertase to Mediate Efficient Components of the Complement Alternative Decay-Accelerating Factor Must Bind Both (2006) (0)
- A proteolytically truncated form of Shigella Flexneri IpaD (2006) (0)
- Structure of a complex between Neisseria meningitidis factor H binding protein and CCPs 6-7 of human complement factor H (2009) (0)
- Immune escape of Borrelia burgdorferi: assessment of two regions within complement regulator-acquiring surface protein (CRASP)-1 required for structure formation and interaction with the host immune regulators FHL-1 and factor H (2006) (0)
- Salmonella flagellar basal body refined in C1 map (2021) (0)
- Structure of the Shigella flexneri MxiA protein (2012) (0)
- EsxB, EsxC and EsxD facilitate export of the antibacterial nuclease EsaD by the Staphylococcus aureus Type VII secretion system (2023) (0)
- Shigella flexneri MxiC (2008) (0)
- Crystallographic studies of sugar binding by factor H domains 6–8 (2007) (0)
- THE STRUCTURE OF THE TWO N-TERMINAL DOMAINS OF COMPLEMENT FACTOR H RELATED PROTEIN 1 SHOWS FORMATION OF A NOVEL DIMERISATION INTERFACE (2013) (0)
- Identification of Jagged1 as a novel ligand for CD46: An interaction required for normal induction and regulation of human TH1 responses (2012) (0)
- In situ assembled Salmonella FlgD hook cap complex (2021) (0)
- MxiH needle protein of Shigella Flexneri (monomeric form, residues 1- 78) (2006) (0)
- Pseudomonas fluorescens PhoX (2012) (0)
- Notch ligand, Jagged-1, contains an N-terminal C2 domain (2013) (0)
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