Susan A. Martinis
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American biochemist
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Biochemistry
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Biology
Why Is Susan A. Martinis Influential?
(Suggest an Edit or Addition)According to Wikipedia, Susan A. Martinis is an American biochemist. She has co-authored over 57 publications in peer reviewed journals and scientific book chapters. Her expertise is in protein:RNA interactions and aminoacyl tRNA synthetases. As of 2019, she is the Vice Chancellor for Research and Innovation at the University of Illinois at Urbana-Champaign.
Susan A. Martinis's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- An Antifungal Agent Inhibits an Aminoacyl-tRNA Synthetase by Trapping tRNA in the Editing Site (2007) (517)
- A conserved residue of cytochrome P-450 is involved in heme-oxygen stability and activation (1989) (215)
- Structural and mechanistic basis of pre- and posttransfer editing by leucyl-tRNA synthetase. (2003) (200)
- Crystal structure of the cytochrome P-450CAM active site mutant Thr252Ala. (1991) (193)
- Structural dynamics of the aminoacylation and proof-reading functional cycle of bacterial leucyl-tRNA synthetase (2012) (129)
- tRNA synthetase: tRNA aminoacylation and beyond (2014) (128)
- Naturally occurring aminoacyl-tRNA synthetases editing-domain mutations that cause mistranslation in Mycoplasma parasites (2011) (112)
- Aminoacyl‐tRNA synthetases: a family of expanding functionsMittelwihr, France, October 10–15, 1999 (1999) (111)
- A conserved threonine within Escherichia coli leucyl-tRNA synthetase prevents hydrolytic editing of leucyl-tRNALeu. (2001) (108)
- Probing the heme iron coordination structure of pressure-induced cytochrome P420cam. (1996) (101)
- Resonance Raman investigations of Escherichia coli-expressed Pseudomonas putida cytochrome P450 and P420. (1992) (99)
- Alteration of sperm whale myoglobin heme axial ligation by site-directed mutagenesis. (1990) (87)
- Aminoacyl-tRNA synthetases: a new image for a classical family. (1999) (78)
- The balance between pre‐ and post‐transfer editing in tRNA synthetases (2010) (77)
- CP1-dependent partitioning of pretransfer and posttransfer editing in leucyl-tRNA synthetase (2008) (72)
- Amino Acid Toxicities of Escherichia coli That Are Prevented by Leucyl-tRNA Synthetase Amino Acid Editing (2007) (69)
- Fidelity Mechanisms of the Aminoacyl-tRNA Synthetases (2009) (62)
- Rational design to block amino acid editing of a tRNA synthetase. (2002) (62)
- Enzymatic aminoacylation of sequence-specific RNA minihelices and hybrid duplexes with methionine. (1992) (60)
- Control of leucine-dependent mTORC1 pathway through chemical intervention of leucyl-tRNA synthetase and RagD interaction (2017) (57)
- Identification of essential domains for Escherichia coli tRNA(leu) aminoacylation and amino acid editing using minimalist RNA molecules. (2002) (51)
- RNA tetraloops as minimalist substrates for aminoacylation. (1992) (49)
- An inserted region of leucyl‐tRNA synthetase plays a critical role in group I intron splicing (2002) (46)
- The bI4 group I intron binds directly to both its protein splicing partners, a tRNA synthetase and maturase, to facilitate RNA splicing activity. (2000) (46)
- Aminoacyl-tRNA synthetases in biology and disease: new evidence for structural and functional diversity in an ancient family of enzymes. (1997) (46)
- Non-standard amino acid recognition by Escherichia coli leucyl-tRNA synthetase. (1997) (45)
- Functional Divergence of a Unique C-terminal Domain of Leucyl-tRNA Synthetase to Accommodate Its Splicing and Aminoacylation Roles* (2006) (41)
- Small RNA Oligonucleotide Substrates for Specific Aminoacylations (1995) (40)
- Probing the heme iron coordination structure of alkaline chloroperoxidase. (1996) (39)
- A Viable Amino Acid Editing Activity in the Leucyl-tRNA Synthetase CP1-splicing Domain Is Not Required in the Yeast Mitochondria* (2006) (39)
- Two conserved threonines collaborate in the Escherichia coli leucyl-tRNA synthetase amino acid editing mechanism. (2005) (37)
- A prokaryote and human tRNA synthetase provide an essential RNA splicing function in yeast mitochondria. (2000) (33)
- Molecular dissection of a critical specificity determinant within the amino acid editing domain of leucyl-tRNA synthetase. (2004) (33)
- Isolated CP1 domain of Escherichia coli leucyl-tRNA synthetase is dependent on flanking hinge motifs for amino acid editing activity. (2007) (33)
- In vitro assays for the determination of aminoacyl-tRNA synthetase editing activity. (2008) (32)
- Mutational unmasking of a tRNA-dependent pathway for preventing genetic code ambiguity. (2006) (32)
- Non-catalytic regulation of gene expression by aminoacyl-tRNA synthetases. (2014) (28)
- A counterintuitive Mg2+-dependent and modification-assisted functional folding of mitochondrial tRNAs. (2006) (26)
- Microhelix aminoacylation by a class I tRNA synthetase. Non-conserved base pairs required for specificity. (1993) (22)
- A paradigm shift for the amino acid editing mechanism of human cytoplasmic leucyl-tRNA synthetase. (2009) (19)
- Yeast Mitochondrial Leucyl-tRNA Synthetase CP1 Domain Has Functionally Diverged to Accommodate RNA Splicing at Expense of Hydrolytic Editing* (2012) (19)
- Investigations of the resonance Raman excitation profiles of cytochrome P450cam (1987) (19)
- Analysis of the Resistance Mechanism of a Benzoxaborole Inhibitor Reveals Insight into the Leucyl-tRNA Synthetase Editing Mechanism. (2015) (17)
- Defects in Transient tRNA Translocation Bypass tRNA Synthetase Quality Control Mechanisms* (2009) (17)
- Mitigation of SARS-CoV-2 transmission at a large public university (2021) (17)
- Nontranslational function of leucyl-tRNA synthetase regulates myogenic differentiation and skeletal muscle regeneration. (2019) (16)
- Acceptor stem and anticodon RNA hairpin helix interactions with glutamine tRNA synthetase. (1993) (16)
- Functional segregation of a predicted "hinge" site within the beta-strand linkers of Escherichia coli leucyl-tRNA synthetase. (2008) (16)
- Leucyl-tRNA synthetase editing domain functions as a molecular rheostat to control codon ambiguity in Mycoplasma pathogens (2013) (15)
- NMR structure of a ribosomal RNA hairpin containing a conserved CUCAA pentaloop. (2001) (14)
- Modulation of substrate specificity within the amino acid editing site of leucyl-tRNA synthetase. (2007) (14)
- Coordination of tRNA Synthetase Active Sites for Chemical Fidelity* (2012) (14)
- Loss of function mutations in VARS encoding cytoplasmic valyl-tRNA synthetase cause microcephaly, seizures, and progressive cerebral atrophy (2018) (13)
- A Flexible peptide tether controls accessibility of a unique C-terminal RNA-binding domain in leucyl-tRNA synthetases. (2008) (13)
- Leucyl-tRNA Synthetase-dependent and -independent Activation of a Group I Intron* (2009) (12)
- Amino-acid-dependent shift in tRNA synthetase editing mechanisms. (2011) (11)
- Characterization of benzoxaborole‐based antifungal resistance mutations demonstrates that editing depends on electrostatic stabilization of the leucyl‐tRNA synthetase editing cap (2011) (11)
- A unique insert of leucyl-tRNA synthetase is required for aminoacylation and not amino acid editing. (2007) (11)
- Biochemical and phylogenetic analyses of methionyl‐tRNA synthetase isolated from a pathogenic microorganism, Mycobacterium tuberculosis (1998) (10)
- Characterization of cytochrome b5 reconstituted with a ferric chlorin and a ferric oxochlorin. (1989) (10)
- Molecular and functional dissection of a putative RNA-binding region in yeast mitochondrial leucyl-tRNA synthetase. (2007) (9)
- Jekyll & Hyde: evolution of a superfamily. (2007) (8)
- Molecular and Functional Dissection of a Putative RNA-binding Region in Yeast MitochondrialLeucyl-tRNA Synthetase (2007) (6)
- Capture and quality control mechanisms for adenosine-5'-triphosphate binding. (2013) (6)
- A glycine hinge for tRNA‐dependent translocation of editing substrates to prevent errors by leucyl‐tRNA synthetase (2009) (5)
- Isolation of bacterial compartments to track movement of protein synthesis factors. (2017) (4)
- Crystal structure of the cytochrome P-450(CAM) active site mutant Thr252Ala (1993) (4)
- Duplication of leucyl-tRNA synthetase in an archaeal extremophile may play a role in adaptation to variable environmental conditions (2020) (3)
- Ala-His Mediated Peptide Bond Formation Revisited (2001) (2)
- Ternary complex of E. coli leucyl-tRNA synthetase, tRNA(leu) and leucyl-adenylate analogue in the aminoacylation conformation (2012) (1)
- Rational Design to Block Amino Acid Editing of a tRNA Synthetase [J. Am. Chem. Soc. 2002, 124, 7286−7287]. (2003) (1)
- Aminoacyl tRNA Synthetases, Chemistry of (2008) (1)
- Tissue-specific alternative splicing separates the catalytic and cell signaling functions of human leucyl-tRNA synthetase (2022) (1)
- LEUCYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS COMPLEXED WITH A tRNA(leu) transcript with 5-FLUORO-1,3-DIHYDRO-1-HYDROXY-2,1- BENZOXABOROLE (AN2690) forming an adduct to the ribose of adenosine- 76 in the enzyme editing site. (2007) (0)
- Escherichia coli tRNA Induces Mammalian Cell Migration and Socialization (2017) (0)
- Crystal structure of the LeuRS editing domain of Candida albicans in complex with the adduct AN2690-AMP (2015) (0)
- Crystal structure of Mycoplasma mobile Leucyl-tRNA Synthetase with Leu-AMS in the active site (2013) (0)
- Ternary complex of E. coli leucyl-tRNA synthetase, tRNA(leu) and leucine in the editing conformation (2012) (0)
- Crystal structure of the LeuRS editing domain of Candida albicans Mutant K510A (2015) (0)
- Control of leucine-dependent mTORC1 pathway through chemical intervention of leucyl-tRNA synthetase and RagD interaction (2017) (0)
- Ternary complex of E. coli leucyl-tRNA synthetase, tRNA(leu) and the benzoxaborole AN2679 in the editing conformation (2012) (0)
- A Non‐Canonical Function of Leucyl tRNA Synthetase Negatively Regulates Skeletal Myogenesis (2017) (0)
- Loss of function mutations in VARS encoding cytoplasmic valyl-tRNA synthetase cause microcephaly, seizures, and progressive cerebral atrophy (2018) (0)
- Translational Regulation of Gene Expression in Mycobacterium: A Means for Coordinating the Expression of Functionally Related Proteins (2017) (0)
- A Catalytic Null Splice Variant of Human Leucyl‐tRNA Synthetase with Enhanced Non‐Canonical Function (2018) (0)
- Enzymatic activation of cytochrome P-450(cam) (1990) (0)
- LEUCYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS COMPLEXED WITH A SULPHAMOYL ANALOGUE OF LEUCYL-ADENYLATE In the synthetic site and an adduct of AMP with 5-Fluoro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole (AN2690) in the editing site (2007) (0)
- Crystal structure of the LeuRS editing domain of Candida albicans Mutant K510A in complex with the adduct formed by AN2690-AMP (2015) (0)
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