Suse Broyde
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American chemical biologist and academic
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Suse Broydechemistry Degrees
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Organic Chemistry
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Chemistry Biology
Suse Broyde's Degrees
- Masters Chemistry Stanford University
- Bachelors Chemistry University of California, Berkeley
Why Is Suse Broyde Influential?
(Suggest an Edit or Addition)According to Wikipedia, Suse Broyde is an American chemical biologist who is a Professor of Biology and Affiliate Professor of Chemistry at New York University. Her research focuses on the molecular mechanisms that process DNA damage induced by environmental and endogenous carcinogens, notably mutagenesis and repair.
Suse Broyde's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- NMR solution structures of stereoisometric covalent polycyclic aromatic carcinogen-DNA adduct: principles, patterns, and diversity. (1997) (243)
- Solution conformation of the major adduct between the carcinogen (+)-anti-benzo[a]pyrene diol epoxide and DNA. (1992) (203)
- Stepwise Translocation of Dpo4 Polymerase during Error-Free Bypass of an oxoG Lesion (2006) (153)
- Thermodynamic and structural factors in the removal of bulky DNA adducts by the nucleotide excision repair machinery (2002) (126)
- A water-mediated and substrate-assisted catalytic mechanism for Sulfolobus solfataricus DNA polymerase IV. (2007) (110)
- Influence of benzo[a]pyrene diol epoxide chirality on solution conformations of DNA covalent adducts: the (-)-trans-anti-[BP]G.C adduct structure and comparison with the (+)-trans-anti-[BP]G.C enantiomer. (1992) (109)
- Nuclear magnetic resonance solution structures of covalent aromatic amine-DNA adducts and their mutagenic relevance. (1998) (105)
- Solution conformation of the (+)-cis-anti-[BP]dG adduct in a DNA duplex: intercalation of the covalently attached benzo[a]pyrenyl ring into the helix and displacement of the modified deoxyguanosine. (1993) (103)
- Structural characterization of an N-acetyl-2-aminofluorene (AAF) modified DNA oligomer by NMR, energy minimization, and molecular dynamics. (1993) (101)
- NMR and computational characterization of the N-(deoxyguanosin-8-yl)aminofluorene adduct [(AF)G] opposite adenosine in DNA: (AF)G[syn].A[anti] pair formation and its pH dependence. (1989) (99)
- The human DNA repair factor XPC‐HR23B distinguishes stereoisomeric benzo[a]pyrenyl‐DNA lesions (2007) (97)
- Polymerase beta simulations suggest that Arg258 rotation is a slow step rather than large subdomain motions per se. (2002) (81)
- The Chemical Biology of DNA Damage (2010) (80)
- Lesion processing: high-fidelity versus lesion-bypass DNA polymerases. (2008) (67)
- Structural basis for the recognition of diastereomeric 5′,8-cyclo-2′-deoxypurine lesions by the human nucleotide excision repair system (2014) (66)
- The sequence dependence of human nucleotide excision repair efficiencies of benzo[a]pyrene-derived DNA lesions: insights into the structural factors that favor dual incisions. (2009) (65)
- NMR and computational characterization of mitomycin cross-linked to adjacent deoxyguanosines in the minor groove of the d(T-A-C-G-T-A).d(T-A-C-G-T-A) duplex. (1990) (62)
- Prediction of DNA structure from sequence: A build‐up technique (1989) (61)
- Resistance of bulky DNA lesions to nucleotide excision repair can result from extensive aromatic lesion–base stacking interactions (2011) (60)
- Nucleotide excision repair of 2-acetylaminofluorene- and 2-aminofluorene-(C8)-guanine adducts: molecular dynamics simulations elucidate how lesion structure and base sequence context impact repair efficiencies (2012) (58)
- DNA adducts from a tumorigenic metabolite of benzo[a]pyrene block human RNA polymerase II elongation in a sequence- and stereochemistry-dependent manner. (2002) (58)
- Spectral Properties of Chlorophyllin a (1964) (57)
- Substrate Discrimination by Formamidopyrimidine-DNA Glycosylase (2004) (56)
- Methylation of cytosine at C5 in a CpG sequence context causes a conformational switch of a benzo[a]pyrene diol epoxide-N2-guanine adduct in DNA from a minor groove alignment to intercalation with base displacement. (2005) (53)
- Conformation of the deoxydinucleoside monophosphate dCpdG modified at carbon 8 of guanine with 2-(acetylamino)fluorene. (1982) (53)
- Probing for DNA damage with β-hairpins: similarities in incision efficiencies of bulky DNA adducts by prokaryotic and human nucleotide excision repair systems in vitro. (2011) (51)
- Absolute configurations of spiroiminodihydantoin and allantoin stereoisomers: comparison of computed and measured electronic circular dichroism spectra. (2009) (51)
- DNA adduct structure-function relationships: comparing solution with polymerase structures. (2008) (50)
- Molecular topology of polycyclic aromatic carcinogens determines DNA adduct conformation: a link to tumorigenic activity. (2001) (49)
- Solution conformation of the (+)-trans-anti-[BPh]dA adduct opposite dT in a DNA duplex: intercalation of the covalently attached benzo[c]phenanthrene to the 5'-side of the adduct site without disruption of the modified base pair. (1993) (49)
- Local deformations revealed by dynamics simulations of DNA polymerase Beta with DNA mismatches at the primer terminus. (2002) (48)
- Solution conformation of the (-)-cis-anti-benzo[a]pyrenyl-dG adduct opposite dC in a DNA duplex: intercalation of the covalently attached BP ring into the helix with base displacement of the modified deoxyguanosine into the major groove. (1996) (48)
- Molecular basis for damage recognition and verification by XPC-RAD23B and TFIIH in nucleotide excision repair. (2018) (48)
- Solution conformation of the (-)-trans-anti-benzo[c]phenanthrene-dA ([BPh]dA) adduct opposite dT in a DNA duplex: intercalation of the covalently attached benzo[c]phenanthrenyl ring to the 3'-side of the adduct site and comparison with the (+)-trans-anti-[BPh]dA opposite dT stereoisomer. (1995) (47)
- Mechanism of error-free and semi-targeted mutagenic bypass of an aromatic amine lesion by Y-family polymerase Dpo4 (2010) (46)
- Z-DNA conformation of N-2-acetylaminofluorene modified poly(dG-dC).poly(dG-dC) determined by reactivity with anti cytidine antibodies and minimized potential energy calculations. (1981) (45)
- Nucleotide excision repair efficiencies of bulky carcinogen-DNA adducts are governed by a balance between stabilizing and destabilizing interactions. (2012) (44)
- The crystal and molecular structure of a calcium salt of guanylyl-3',5'-cytidine (GpC) (1976) (44)
- Substrate discrimination by formamidopyrimidine-DNA glycosylase: distinguishing interactions within the active site. (2004) (44)
- Conformation of 2‐aminofluorene‐modified DNA (1983) (44)
- Relating repair susceptibility of carcinogen-damaged DNA with structural distortion and thermodynamic stability. (2002) (43)
- Stereochemical, structural, and thermodynamic origins of stability differences between stereoisomeric benzo[a]pyrene diol epoxide deoxyadenosine adducts in a DNA mutational hot spot sequence. (2001) (43)
- Mutation and repair induced by the carcinogen 2-(hydroxyamino)-1-methyl-6-phenylimidazo[4,5-b]pyridine (N-OH-PhIP) in the dihydrofolate reductase gene of Chinese hamster ovary cells and conformational modeling of the dG-C8-PhIP adduct in DNA. (1994) (43)
- Differential nucleotide excision repair susceptibility of bulky DNA adducts in different sequence contexts: hierarchies of recognition signals. (2009) (43)
- Dynamics of a benzo[a]pyrene-derived guanine DNA lesion in TGT and CGC sequence contexts: enhanced mobility in TGT explains conformational heterogeneity, flexible bending, and greater susceptibility to nucleotide excision repair. (2007) (42)
- Highly organized but pliant active site of DNA polymerase beta: compensatory mechanisms in mutant enzymes revealed by dynamics simulations and energy analyses. (2004) (41)
- Carcinogen–base stacking and base–base stacking in dCpdG modified by (+) and (−) anti‐BPDE (1985) (41)
- Structural and thermodynamic features of spiroiminodihydantoin damaged DNA duplexes. (2005) (41)
- Solution structure of the aminofluorene [AF]-external conformer of the anti-[AF]-C8-dG adduct opposite dC in a DNA duplex. (1998) (40)
- Repair-Resistant DNA Lesions (2017) (40)
- The N-clasp of human DNA polymerase κ promotes blockage or error-free bypass of adenine- or guanine-benzo[a]pyrenyl lesions (2008) (40)
- A new anti conformation for N-(deoxyguanosin-8-yl)-2-acetylaminofluorene (AAF-dG) allows Watson–Crick pairing in the Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4) (2006) (39)
- Emission spectra of chlorophyll-alpha in polar and nonpolar solvents. (1967) (38)
- Adenine-DNA adducts derived from the highly tumorigenic Dibenzo[a,l]pyrene are resistant to nucleotide excision repair while guanine adducts are not. (2013) (37)
- Structure and mechanism of pyrimidine–pyrimidone (6-4) photoproduct recognition by the Rad4/XPC nucleotide excision repair complex (2019) (36)
- DNA cytosine methylation: structural and thermodynamic characterization of the epigenetic marking mechanism. (2013) (36)
- THE MECHANISM OF THE FLAVIN SENSITIZED PHOTODESTRUCTION OF INDOLEACETIC ACID* (1967) (36)
- Structures of the (+)- and (-)-trans-7,8-dihydroxy-anti-9,10-epoxy-7,8,9,10-tetrahydrobenzo(a)pyre ne adducts to guanine-N2 in a duplex dodecamer. (1991) (36)
- Impact of conformational heterogeneity of OxoG lesions and their pairing partners on bypass fidelity by Y family polymerases. (2009) (35)
- Exocyclic amino groups of flanking guanines govern sequence-dependent adduct conformations and local structural distortions for minor groove-aligned benzo[a]pyrenyl-guanine lesions in a GG mutation hotspot context (2007) (35)
- Solution conformation of the (-)-trans-anti-[BP]dG adduct opposite a deletion site in a DNA duplex: intercalation of the covalently attached benzo[a]pyrene into the helix with base displacement of the modified deoxyguanosine into the minor groove. (1994) (34)
- Base Sequence Context Effects on Nucleotide Excision Repair (2010) (34)
- Solution conformation of the N-(deoxyguanosin-8-yl)-1-aminopyrene ([AP]dG) adduct opposite dC in a DNA duplex. (1996) (34)
- Accurate representation of B-DNA double helical structure with implicit solvent and counterions. (2002) (33)
- Effect of ring size on conformations of aromatic amine-DNA adducts: the aniline-C8 guanine adduct resides in the B-DNA major groove. (1998) (33)
- Evading the proofreading machinery of a replicative DNA polymerase: induction of a mutation by an environmental carcinogen. (2001) (33)
- The relationships between XPC binding to conformationally diverse DNA adducts and their excision by the human NER system: is there a correlation? (2014) (32)
- Structural alignments of (+)- and (-)-trans-anti-benzo[a]pyrene-dG adducts positioned at a DNA template-primer junction. (1995) (32)
- Solution structure of the aminofluorene [AF]-intercalated conformer of the syn-[AF]-C8-dG adduct opposite dC in a DNA duplex. (1998) (32)
- Preferred WMSA catalytic mechanism of the nucleotidyl transfer reaction in human DNA polymerase κ elucidates error-free bypass of a bulky DNA lesion (2012) (31)
- Transcription elongation past O6-methylguanine by human RNA polymerase II and bacteriophage T7 RNA polymerase (2008) (31)
- Minor-groove binding models for acetylaminofluorene modified DNA. (1989) (31)
- The Spacious Active Site of a Y-Family DNA Polymerase Facilitates Promiscuous Nucleotide Incorporation Opposite a Bulky Carcinogen-DNA Adduct (2004) (30)
- Nucleotide Excision Repair Lesion-Recognition Protein Rad4 Captures a Pre-Flipped Partner Base in a Benzo[a]pyrene-Derived DNA Lesion: How Structure Impacts the Binding Pathway (2017) (29)
- Classical potential energy calculations for ApA, CpC, GpG, and UpU. The influence of the bases on RNA subunit conformations (1975) (29)
- Distant neighbor base sequence context effects in human nucleotide excision repair of a benzo[a]pyrene-derived DNA lesion. (2010) (29)
- Structural, energetic and dynamic properties of guanine(C8)–thymine(N3) cross-links in DNA provide insights on susceptibility to nucleotide excision repair (2011) (28)
- Human RNA polymerase II is partially blocked by DNA adducts derived from tumorigenic benzo[c]phenanthrene diol epoxides: relating biological consequences to conformational preferences. (2003) (28)
- Base flipping free energy profiles for damaged and undamaged DNA. (2010) (27)
- Spiroiminodihydantoin lesions derived from guanine oxidation: structures, energetics, and functional implications. (2005) (27)
- Assignment of absolute configurations of the enantiomeric spiroiminodihydantoin nucleobases by experimental and computational optical rotatory dispersion methods. (2006) (27)
- Low temperature absorption spectra of chlorophyll a in polar and nonpolar solvents. (1968) (27)
- Structural alignment of the (+)-trans-anti-benzo[a]pyrene-dG adduct positioned opposite dC at a DNA template-primer junction. (1997) (27)
- Stereochemical origin of opposite orientations in DNA adducts derived from enantiomeric anti-benzo[a]pyrene diol epoxides with different tumorigenic potentials. (1999) (27)
- Intercalative conformations of the 14R (+)- and 14S (-)-trans-anti-DB[a,l]P-N⁶-dA adducts: molecular modeling and MD simulations. (2011) (26)
- Polymerase-tailored variations in the water-mediated and substrate-assisted mechanism for nucleotidyl transfer: insights from a study of T7 DNA polymerase. (2009) (26)
- Bypass of DNA-Protein Cross-links Conjugated to the 7-Deazaguanine Position of DNA by Translesion Synthesis Polymerases* (2016) (26)
- Energy minimized structures of carcinogen-DNA adducts: 2-acetylaminofluorene and 2-aminofluorene. (1986) (26)
- Exploring damage recognition models in prokaryotic nucleotide excision repair with a benzo[a]pyrene-derived lesion in UvrB. (2009) (26)
- Toward understanding the mutagenicity of an environmental carcinogen: structural insights into nucleotide incorporation preferences. (2002) (26)
- Extending the understanding of mutagenicity: structural insights into primer-extension past a benzo[a]pyrene diol epoxide-DNA adduct. (2003) (26)
- Simulating structural and thermodynamic properties of carcinogen-damaged DNA. (2003) (26)
- Structure of guanosine‐3′,5′‐cytidine monophosphate. I. Semi‐empirical potential energy calculations and model‐building (1973) (25)
- 5-Formylcytosine mediated DNA–protein cross-links block DNA replication and induce mutations in human cells (2018) (25)
- Solution structure of the N-(deoxyguanosin-8-yl)-1-aminopyrene ([AP]dG) adduct opposite dA in a DNA duplex. (1999) (25)
- Lesion specificity in the base excision repair enzyme hNeil1: modeling and dynamics studies. (2007) (25)
- Conformation of d(CpG) modified by the carcinogen 4-aminobiphenyl: a combined experimental and theoretical analysis. (1986) (25)
- An analysis of the structural and energetic properties of deoxyribose by potential energy methods (1987) (24)
- Recognition of Damaged DNA for Nucleotide Excision Repair: A Correlated Motion Mechanism with a Mismatched cis-syn Thymine Dimer Lesion (2015) (24)
- Nucleotide selectivity opposite a benzo[a]pyrene-derived N2-dG adduct in a Y-family DNA polymerase: a 5'-slippage mechanism. (2008) (24)
- Transcription processing at 1,N2-ethenoguanine by human RNA polymerase II and bacteriophage T7 RNA polymerase. (2008) (24)
- DNA Damage, Mutagenesis, and DNA Repair (2010) (23)
- Ribonucleotides as nucleotide excision repair substrates. (2014) (23)
- Origins of conformational differences between cis and trans DNA adducts derived from enantiomeric anti-benzo[a]pyrene diol epoxides. (1999) (23)
- Solution structures of aminofluorene [AF]-stacked conformers of the syn [AF]-C8-dG adduct positioned opposite dC or dA at a template-primer junction. (1999) (23)
- Solution structure of the (+)-cis-anti-benzo[a]pyrene-dA ([BP]dA) adduct opposite dT in a DNA duplex. (1999) (23)
- Conformational origin of the pyrimidine (3'-5') purine base sequence preference for intercalation into RNAs. (1979) (23)
- Conformational stability in dinucleoside phosphate crystals. Semiempirical potential energy calculations for uridylyl‐3′‐5′‐adenosine monophosphate (UpA) and guanylyl‐3′,5′‐cytidine monophosphate (GpC) (1974) (22)
- Photochemical Properties of Chlorophyllin a (1964) (21)
- Influence of the carcinogen 4-aminobiphenyl on DNA conformation. (1985) (21)
- DNA backbone conformation in cis–syn pyrimidine[]pyrimidine cyclobutane dimers (1980) (21)
- Structure of guanylyl‐3′,5′‐cytidine monophosphate. II. Description of the molecular and crystal structure of the calcium derivative in space group P21 (1975) (21)
- Enhanced spontaneous DNA twisting/bending fluctuations unveiled by fluorescence lifetime distributions promote mismatch recognition by the Rad4 nucleotide excision repair complex (2017) (21)
- Spectral studies of a chlorophyll pigment with fluorescence maximum at 698 mu. (1966) (21)
- Synthesis and conformation of a dinucleoside monophosphate modified by aniline. (1988) (20)
- Conformational analysis of the major DNA adduct derived from the food mutagen 2-amino-3-methylimidazo[4,5-f]quinoline. (1999) (20)
- Solution conformation of the N-(deoxyguanosin-8-yl)aminofluorene adduct opposite deoxyinosine and deoxyguanosine in DNA by NMR and computational characterization. (1995) (20)
- Role of base sequence context in conformational equilibria and nucleotide excision repair of benzo[a]pyrene diol epoxide-adenine adducts. (2003) (20)
- Studies on the conformation and dynamics of the C8-substituted guanine adduct of the carcinogen acetylaminofluorene; model for a possible Z-DNA modified structure. (1984) (20)
- Surface reactions of chlorophyll a monolayers at a water-air interface. Photochemistry and complex formation. (1969) (20)
- Role of structural and energetic factors in regulating repair of a bulky DNA lesion with different opposite partner bases. (2013) (20)
- The influence of terminal 3', 5' phosphates on conformations of dApdA. (1979) (20)
- Accommodation of an N-(deoxyguanosin-8-yl)-2-acetylaminofluorene adduct in the active site of human DNA polymerase iota: Hoogsteen or Watson-Crick base pairing? (2009) (19)
- Mutagenic nucleotide incorporation and hindered translocation by a food carcinogen C8-dG adduct in Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4): modeling and dynamics studies (2006) (19)
- Solution structure of the aminofluorene-intercalated conformer of the syn [AF]-C8-dG adduct opposite a--2 deletion site in the NarI hot spot sequence context. (1997) (19)
- Conformations of stereoisomeric base adducts to 4-hydroxyequilenin. (2003) (18)
- A slipped replication intermediate model is stabilized by the syn orientation of N-2-aminofluorene- and N-2-(acetyl)aminofluorene-modified guanine at a mutational hotspot. (1998) (18)
- Equilenin-derived DNA adducts to cytosine in DNA duplexes: structures and thermodynamics. (2005) (17)
- Transcription of DNA containing the 5-guanidino-4-nitroimidazole lesion by human RNA polymerase II and bacteriophage T7 RNA polymerase. (2008) (17)
- Solution conformation of the (+)-cis-anti-[BP]dG adduct opposite a deletion site in a DNA duplex: intercalation of the covalently attached benzo[a]pyrene into the helix with base displacement of the modified deoxyguanosine into the minor groove. (1994) (17)
- Accomodation of S-cis-tamoxifen-N(2)-guanine adduct within a bent and widened DNA minor groove. (2000) (17)
- Free energy profiles of base flipping in intercalative polycyclic aromatic hydrocarbon-damaged DNA duplexes: energetic and structural relationships to nucleotide excision repair susceptibility. (2013) (16)
- Solution conformation of [AF]dG opposite a -1 deletion site in a DNA duplex: intercalation of the covalently attached aminofluorene ring into the helix with base displacement of the C8-modified Syn guanine into the major groove. (1995) (16)
- Nucleosome Histone Tail Conformation and Dynamics: Impacts of Lysine Acetylation and a Nearby Minor Groove Benzo[a]pyrene-Derived Lesion. (2017) (16)
- Visualization of an AAF induced frameshift mutation: molecular views of base displacement in B-DNA from minimized potential energy calculations. (1987) (16)
- Solution properties and computational analysis of an oligodeoxynucleotide containing N-(deoxyguanosin-8-yl)-1-aminopyrene. (1996) (16)
- Nucleotide Excision Repair and Impact of Site-Specific 5',8-Cyclopurine and Bulky DNA Lesions on the Physical Properties of Nucleosomes. (2018) (16)
- 4-hydroxyequilenin-adenine lesions in DNA duplexes: stereochemistry, damage site, and structure. (2007) (16)
- Structural and Dynamic Characterization of Polymerase κ’s Minor Groove Lesion Processing Reveals How Adduct Topology Impacts Fidelity (2014) (15)
- Influence of local sequence context on damaged base conformation in human DNA polymerase ι: molecular dynamics studies of nucleotide incorporation opposite a benzo[a]pyrene-derived adenine lesion (2009) (15)
- Helix geometry of single stranded DNA 'A' and 'B' forms from minimum energy conformations of dimeric subunits (1978) (15)
- Lesion Sensing during Initial Binding by Yeast XPC/Rad4: Toward Predicting Resistance to Nucleotide Excision Repair (2018) (15)
- Visualizing sequence-governed nucleotide selectivities and mutagenic consequences through a replicative cycle: processing of a bulky carcinogen N2-dG lesion in a Y-family DNA polymerase. (2009) (15)
- Solution conformation of the (+)-trans-anti-[BP]dG adduct opposite a deletion site in a DNA duplex: intercalation of the covalently attached benzo[a]pyrene into the helix with base displacement of the modified deoxyguanosine into the major groove. (1994) (15)
- Absolute configurations of DNA lesions determined by comparisons of experimental ECD and ORD spectra with DFT calculations. (2009) (15)
- Solution structure of the aminofluorene-stacked conformer of the syn [AF]-C8-dG adduct positioned at a template-primer junction. (1997) (14)
- Transcriptional Bypass of DNA-protein and DNA-peptide Conjugates by T7 RNA Polymerase. (2019) (14)
- 5-Formylcytosine-induced DNA–peptide cross-links reduce transcription efficiency, but do not cause transcription errors in human cells (2019) (14)
- AAF linked to the guanine amino group: a B-Z junction. (1983) (14)
- Absorption difference spectroscopy of chlorophyll a in ethanol solution. (1968) (14)
- Conformation of amine-modified DNA: 2-aminofluorene- and 2-(acetylamino)fluorene-modified deoxydinucleoside monophosphates with all possible nearest neighbors. A comparison of search and optimization methods. (1994) (14)
- Conformational properties of equilenin-DNA adducts: stereoisomer and base effects. (2008) (13)
- Comparative Mutagenesis of the C8-Guanine Adducts of 1-Nitropyrene and 1,6- and 1,8-Dinitropyrene in a CpG Repeat Sequence (2002) (13)
- Principles Governing Conformations in Stereoisomeric Adducts of Bay Region Benzo[a]pyrene Diol Epoxides to Adenine in DNA: Steric and Hydrophobic Effects Are Dominant (2000) (13)
- Following an environmental carcinogen N2-dG adduct through replication: elucidating blockage and bypass in a high-fidelity DNA polymerase (2007) (13)
- A molecular mechanics and dynamics study of the minor adduct between DNA and the carcinogen 2-(acetylamino)fluorene (dG-N2-AAF). (1997) (13)
- Recognition and Removal of Bulky DNA Lesions by the Nucleotide Excision Repair System (2010) (12)
- A bulky DNA lesion derived from a highly potent polycyclic aromatic tumorigen stabilizes nucleosome core particle structure. (2010) (12)
- Accommodation of a 1S-(-)-benzo[c]phenanthrenyl-N6-dA adduct in the Y-family Dpo4 DNA polymerase active site: structural insights through molecular dynamics simulations. (2005) (12)
- Molecular dynamics of a food carcinogen-DNA adduct in a replicative DNA polymerase suggest hindered nucleotide incorporation and extension. (2005) (12)
- Solution conformation of the (-)-trans-anti-5-methylchrysene-dG adduct opposite dC in a DNA duplex: DNA bending associated with wedging of the methyl group of 5-methylchrysene to the 3'-side of the modification site. (1995) (12)
- Rotational and translational positions determine the structural and dynamic impact of a single ribonucleotide incorporated in the nucleosome. (2019) (12)
- Solution conformation of [AF]dG opposite a -2 deletion site in a DNA duplex: intercalation of the covalently attached aminofluorene ring into the helix with base displacement of the C8-modified syn guanine and adjacent unpaired 3'-adenine into the major groove. (1995) (12)
- Photochemical Properties of Water-Soluble Chlorophyll (1961) (12)
- Differences in the Access of Lesions to the Nucleotide Excision Repair Machinery in Nucleosomes. (2015) (12)
- Cyclohexene ring and Fjord region twist inversion in stereoisomeric DNA adducts of enantiomeric benzo[c]phenanthrene diol epoxides. (2001) (11)
- Conformational determinants of structures in stereoisomeric cis-opened anti-benzo[a]pyrene diol epoxide adducts to adenine in DNA. (2000) (11)
- Flexible 5-guanidino-4-nitroimidazole DNA lesions: structures and thermodynamics. (2006) (11)
- Resistance to Nucleotide Excision Repair of Bulky Guanine Adducts Opposite Abasic Sites in DNA Duplexes and Relationships between Structure and Function (2015) (11)
- Interactions between DNA polymerase beta and the major covalent adduct of the carcinogen (+)-anti-benzo[a]pyrene diol epoxide with DNA at a primer-template junction. (1998) (10)
- 'A' forms of RNAs in single strands, duplexes and RNA-DNA hybrids. (1978) (10)
- Solution structure of an O6-[4-oxo-4-(3-pyridyl)butyl]guanine adduct in an 11 mer DNA duplex: evidence for formation of a base triplex. (2003) (10)
- Concentration quenching of proflavine hydrochloride in dry films of sodium deoxyribonucleate and poly (vinyl alcohol) (1971) (9)
- The Nonbulky DNA Lesions Spiroiminodihydantoin and 5-Guanidinohydantoin Significantly Block Human RNA Polymerase II Elongation in Vitro. (2017) (9)
- Major and minor groove conformations of DNA trimers modified on guanine or adenine by 4-aminobiphenyl: adenine adducts favor the minor groove. (1995) (9)
- Introduction and Perspectives on the Chemistry and Biology of DNA Damage (2010) (9)
- Erratum: Resistance to Nucleotide Excision Repair of Bulky Guanine Adducts Opposite Abasic Sites in DNA Duplexes and Relationships between Structure and Function (PLoS ONE (2015) 10:9 (e0137124) DOI:10.1371/journal.pone.0137124) (2015) (9)
- F698: A PIGMENT FOUND IN PREPARATIONS OF CHLOROPHYLL. (1965) (9)
- Nuclear magnetic resonance solution structure of an N(2)-guanine DNA adduct derived from the potent tumorigen dibenzo[a,l]pyrene: intercalation from the minor groove with ruptured Watson-Crick base pairing. (2012) (9)
- Chlorophyll-sensitized oxidation-reduction reactions of hemin in pyridine. (1968) (9)
- Mutagenicity of Polycyclic Aromatic Hydrocarbons and Amines: A Conformational Hypothesis a (1984) (8)
- Determination of absolute configurations of 4-hydroxyequilenin-cytosine and -adenine adducts by optical rotatory dispersion, electronic circular dichroism, density functional theory calculations, and mass spectrometry. (2008) (8)
- Altering DNA polymerase incorporation fidelity by distorting the dNTP binding pocket with a bulky carcinogen-damaged template. (2004) (8)
- Base sequence effects in bending induced by bulky carcinogen-DNA adducts: experimental and computational analysis. (2001) (7)
- Synergistic effects of H3 and H4 nucleosome tails on structure and dynamics of a lesion-containing DNA: Binding of a displaced lesion partner base to the H3 tail for GG-NER recognition. (2018) (7)
- The food mutagen 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline: a conformational analysis of its major DNA adduct and comparison with the 2-amino-3-methylimidazo[4,5-f]quinoline adduct. (2001) (7)
- Tethering-facilitated DNA ‘opening’ and complementary roles of β-hairpin motifs in the Rad4/XPC DNA damage sensor protein (2020) (7)
- A conformational analysis of the (+) anti BPDE adduct to the guanine amino group of dCpdG. (1983) (7)
- Increased Flexibility Enhances Misincorporation (2007) (7)
- Entrapment of a Histone Tail by a DNA Lesion in a Nucleosome Suggests the Lesion Impacts Epigenetic Marking: A Molecular Dynamics Study (2015) (7)
- Conformational searches elucidate effects of stereochemistry on structures of deoxyadenosine covalently bound to tumorigenic metabolites of benzo[C] phenanthrene. (2004) (7)
- A model for the single stranded random coil form of polydeoxyadenylic acid from minimum energy conformations of the dimeric subunit. (1978) (7)
- Nuclear Magnetic Resonance Studies of an N2-Guanine Adduct Derived from the Tumorigen Dibenzo[a,l]pyrene in DNA: Impact of Adduct Stereochemistry, Size, and Local DNA Sequence on Solution Conformations (2014) (7)
- NMR and computational studies of stereoisomeric equine estrogen-derived DNA cytidine adducts in oligonucleotide duplexes: opposite orientations of diastereomeric forms. (2009) (6)
- DNA repair: How to accurately bypass damage (2010) (6)
- Atomic Resolution Structures of Dna and Dna Modified By Carcinogens (1990) (6)
- Deformations of promoter DNA bound to carcinogens help interpret effects on TATA-element structure and activity (2004) (6)
- Structural and Stereoisomer Effects of Model Estrogen Quinone-Derived DNA Adducts: N6-(2-Hydroxyestron-6(α,β)-yl)-2′ -deoxyadenosine and N2-(2-Hydroxyestron-6(α,β )-yl)-2′-deoxyguanosine (2004) (6)
- Molecular dynamics simulations reveal how H3K56 acetylation impacts nucleosome structure to promote DNA exposure for lesion sensing. (2021) (6)
- PREPARATION OF A COLLOIDAL FORM OF CHLOROPHYLL A FROM CONCENTRATED SOLUTON. (1965) (5)
- Search strategies, minimization algorithms, and molecular dynamics simulations for exploring conformational spaces of nuclear acids (1990) (5)
- Structural and stereoisomer effects of model estrogen quinone-derived DNA adducts: N6-(2-hydroxyestron-6(alpha,beta)-yl)-2'-deoxyadenosine and N2-(2-hydroxyestron-6(alpha,beta)-yl)-2'-deoxyguanosine. (2004) (5)
- Covalent Polycyclic Aromatic Hydrocarbon–DNA Adducts: Carcinogenicity, Structure, and Function (2011) (4)
- The DNA Damage-Sensing NER Repair Factor XPC-RAD23B Does Not Recognize Bulky DNA Lesions with a Missing Nucleotide Opposite the Lesion (2020) (4)
- DNA backbone conformation in AAF modified dCpdG: variable conformational modes of achieving base displacement. (1982) (4)
- Base displacement in AAF and AF modified dCpdG: syn and anti guanine (2009) (4)
- Impact of DNA sequences on DNA 'opening' by the Rad4/XPC nucleotide excision repair complex. (2021) (4)
- Letter: Conformation of guanosine cytidine 3',5'-monophosphate (GpC). (1973) (4)
- Correction: Resistance to Nucleotide Excision Repair of Bulky Guanine Adducts Opposite Abasic Sites in DNA Duplexes and Relationships between Structure and Function (2015) (4)
- Variable impact of conformationally distinct DNA lesions on nucleosome structure and dynamics: Implications for nucleotide excision repair. (2019) (3)
- Mechanism of lesion verification by the human XPD helicase in nucleotide excision repair (2022) (3)
- An internal fluorene model for iodo-N-2-acetylaminofluorene modified DNA. (1983) (3)
- Conformational analysis of a 4-hydroxyequilenin Guanine adduct using density functional theory. (2002) (3)
- Base displacement in AAF-modified Z-DNA. (1985) (3)
- Coil form of Poly(rU): a model composed of minimum energy conformers that matches experimental properties (1979) (3)
- Elucidating Structure–Function Relationships in Bulky DNA Lesions: From Solution Structures to Polymerases (2010) (3)
- Effective Computational Strategies for Determining Structures of Carcinogen-Damaged DNA (1999) (3)
- Nucleotide excision repair of DNA adducts derived from the binding of the equine estrogen metabolite 4-OHEN to dC and dA adducts in vitro. (2006) (2)
- Translesion Synthesis Past 5-Formylcytosine-Mediated DNA-Peptide Cross-Links by hPolη Is Dependent on the Local DNA Sequence. (2021) (2)
- Visualizing Spontaneous DNA Dynamics and its Role in Mismatch Recognition by Damage Recognition Protein Rad4 (2018) (2)
- Erratum: Actin polymerization serves as a membrane domain switch in model lipid bilayers (Biophysical Journal (2006) 91, (4064-4070)) (2007) (1)
- Stop reacting and debate the issue [3] (1971) (1)
- TAMOXIFEN-DNA ADDUCT (2000) (1)
- Setting the stage for predicting RNA thermodynamic properties and their structural components. (1996) (1)
- CONFORMATION OF THE C8 SUBSTITUTED GUANINE ADDUCT OF THE CARCINOGEN ACETYLAMINOFLUORENE - MODEL FOR A POSSIBLE Z-DNA MODIFIED STRUCTURE (1984) (1)
- Unusual Hydrogen Bonding Patterns in 2-Aminofluorene (AF) and 2-Acetylaminofluorene (AAF) Modified DNA (1990) (1)
- Impact of DNA sequences in the DNA duplex opening by the Rad4/XPC nucleotide excision repair complex (2020) (1)
- Conformations of DNA Modified by the Carcinogen 4‐Aminobiphenyl a (1986) (1)
- Interactions of carcinogens with DNA (deoxyribonucleic acid) (1989) (0)
- SOLUTION STRUCTURE OF THE [AF]-C8-DG ADDUCT POSITIONED AT A TEMPLATE-PRIMER JUNCTION, NMR, 6 STRUCTURES (1998) (0)
- Molecular dynamics simulation of a benzo pyrene diol epoxide modified guanine mismatched with adenine at a primer-template junction in T7 DNA polymerase (2000) (0)
- Molecular understanding of mutagenicity using potential energy methods. Progress report, July 1, 1992--September 30, 1993 (1993) (0)
- Molecular understanding of mutagenicity using potential energy methods. Progress report, January 1, 1990--June 30, 1992 (1990) (0)
- Conformation of a Rare Nucleoside in the Anti- Calculations for 2'- 0-Methyl Cytidine Codon Loop of tRNAs: Potential Energy (1975) (0)
- NMR SOLUTION STRUCTURES OF ADDUCTS FROM THE BINDING OF POLYCYCLIC AROMATIC DIOL EPOXIDES TO DNA (2008) (0)
- Unusual hydrogen bonding patterns in AF (aminofluorene) and AAF (acetylaminofluorene) modified DNA (1989) (0)
- STRUCTURAL ALIGNMENT OF THE (+)-TRANS-ANTI-[BP]DG ADDUCT POSITIONED OPPOSITE DC AT A DNA TEMPLATE-PRIMER JUNCTION, NMR, 6 STRUCTURES (1998) (0)
- Solution structure and 5{prime}-intercalation of the polynuclear aromatic BP residue in a (+)-cis-anti-[BP]-N{sup 6}-dA adduct opposite dT in a DNA duplex (1996) (0)
- SOLUTION CONFORMATION OF THE (-)-TRANS-ANTI-[BP]DG ADDUCT OPPOSITE A DELETION SITE IN DNA DUPLEX D(CCATC-[BP]G-CTACC)D(GGTAG--GATGG), NMR, 6 STRUCTURES (1998) (0)
- Light-induced modulation of DNA recognition by the Rad4/XPC damage sensor protein (2020) (0)
- Unmodified Insertion Ternary Complex (2006) (0)
- Nucleic Acids Research Aaf Linked Co the Guanine Amino Group: a B-z Junction (0)
- The torsion space nucleic acids molecular mechanics program DUPLEX: Surveying conformation space by potential energy minimization. Progress report (1993) (0)
- Robert Shapiro (1935–2011) (2011) (0)
- oxoG-modified Insertion Ternary Complex (2006) (0)
- NMR solution structures of adducts derived from the binding of polycyclic aromatic diol epoxides to DNA (1995) (0)
- Development of a new computational approach for the prediction of nucleic acid structure by potential energy methods: I. Deoxyribose (1986) (0)
- Deformation of DNA by carcinogenic agents (1981) (0)
- SOLUTION NMR STRUCTURE OF THE [AP]DG ADDUCT OPPOSITE DA IN A DNA DUPLEX, NMR, 9 STRUCTURES (1998) (0)
- oxoG-modified Preinsertion Binary Complex (2006) (0)
- 5-Formylcytosine mediated DNA–protein cross-links block DNA replication and induce mutations in human cells (2018) (0)
- Molecular views of damaged DNA: Adaptation of the Program DUPLEX to parallel architectures (1994) (0)
- Static and animated molecular views of a tumorigenic chemical bound to DNA (1991) (0)
- The molecular mechanics program DUPLEX: Computing structures of carcinogen modified DNA by surveying the potential energy surface (1995) (0)
- Modeling DNA Replication Intermediates (1997) (0)
- Corrigendum: 5-Formylcytosine mediated DNA - Protein cross-links block DNA replication and induce mutations in human cells (Nucleic Acids Research (2018) 46:13 (6455-6469) DOI: 10.1093/nar/gky444) (2018) (0)
- Unmodified preinsertion binary complex (2006) (0)
- SOLUTION STRUCTURE OF THE [AF]-C8-DG ADDUCT OPPOSITE A-2 DELETION SITE IN THE NARI HOT SPOT SEQUENCE CONTEXT; NMR, 6 STRUCTURES (1998) (0)
- SOLUTION NMR STRUCTURE OF THE [BP]DA ADDUCT OPPOSITE DT IN A DNA DUPLEX, 6 STRUCTURES (1998) (0)
- SOLUTION STRUCTURE OF THE [AF]-C8-DG ADDUCT POSITIONED OPPOSITE DA AT A TEMPLATE-PRIMER JUNCTION (1999) (0)
- Solution Structure of an O 6 -[4-oxo-4-(3-Pyridyl)butyl]guanine Adduct in an 11mer DNA Duplex (2004) (0)
- Molecular conformations of DNA and RNA subunits (1977) (0)
- oxoG-modified Postinsertion Binary Complex (2006) (0)
- Conformations of DNA adducts with polycyclic aromatic carcinogens. (1985) (0)
- Inhibition of E. coli RecQ Helicase Activity by Structurally Distinct DNA Lesions: Structure—Function Relationships (2022) (0)
- Conformations of DNA Modified by Carcinogenic Aromatic Amines: 2‐Aminofluorene and 2‐Acetylaminofluorene Energy‐Refined Tetramer Models a (1987) (0)
- PHOTOCHEMICAL AND SPECTRAL PROPERTIES OF CHLOROPHYLLIN. (1963) (0)
- Structures of the ( + )-and (-)-fra / is-7 , 8-Dihydroxy-fl / if /-9 , 10-epoxy-7 , 8 , 9 , 10-tetrahydrobenzo ( a ) pyrene Adducts to Guanine-/ V 2 in a Duplex Dodecamer 1 (2006) (0)
- Volume 5 Number 1 January 1978 NliCleJC Acids Research Helix geometry of single stranded DNA ' A ' and ' B ' forms from minimum energy conformations of dimeric su bun its (2005) (0)
- NMR studies of N2-guanine adducts derived from the tumorigen dibenzo[a,l]pyrene in DNA: Impact of adduct stereochemistry, size, and local DNA structure on solution conformations (2014) (0)
- Environmental Carcinogens: Polycyclic Hydrocarbons and Carcinogenesis . Ronald G. Harvey, Ed. American Chemical Society, Washington, D.C., 1985. x, 406 pp., illus. $74.95. ACS Symposium Series, 283. From a symposium, Philadelphia, Aug. 1984. (1985) (0)
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