Suzanne Walker
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American biochemist and researcher
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Suzanne Walkerbiology Degrees
Biology
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Molecular Biology
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#238
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Biochemistry
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Biology
Suzanne Walker's Degrees
- Bachelors Biochemistry University of California, Berkeley
- PhD Biochemistry Stanford University
Why Is Suzanne Walker Influential?
(Suggest an Edit or Addition)According to Wikipedia, Suzanne Walker is a professor of Microbiology and Molecular Genetics at Harvard University. Her research focuses on mechanisms of antibiotics and antibiotic resistance. She was elected to the National Academy of Sciences in 2020.
Suzanne Walker's Published Works
Published Works
- The bacterial cell envelope. (2010) (2503)
- Wall teichoic acids of gram-positive bacteria. (2013) (666)
- SEDS proteins are a widespread family of bacterial cell wall polymerases (2016) (385)
- Structure of human O-GlcNAc transferase and its complex with a peptide substrate (2010) (376)
- Glycosylation of unreactive substrates (1989) (339)
- Lipid II Is an Intrinsic Component of the Pore Induced by Nisin in Bacterial Membranes* (2003) (318)
- Wall Teichoic Acid Function, Biosynthesis, and Inhibition (2009) (308)
- Lipoprotein Cofactors Located in the Outer Membrane Activate Bacterial Cell Wall Polymerases (2010) (290)
- Comparative Genomics of Enterococci: Variation in Enterococcus faecalis, Clade Structure in E. faecium, and Defining Characteristics of E. gallinarum and E. casseliflavus (2012) (272)
- Synthetic lethal compound combinations reveal a fundamental connection between wall teichoic acid and peptidoglycan biosyntheses in Staphylococcus aureus. (2011) (251)
- Imaging peptidoglycan biosynthesis in Bacillus subtilis with fluorescent antibiotics. (2006) (248)
- The 1.9 Å crystal structure of Escherichia coli MurG, a membrane‐associated glycosyltransferase involved in peptidoglycan biosynthesis (2000) (228)
- Methicillin resistance in Staphylococcus aureus requires glycosylated wall teichoic acids (2012) (224)
- Discovery of O-GlcNAc transferase inhibitors. (2005) (223)
- Crystal structure of the MurG:UDP-GlcNAc complex reveals common structural principles of a superfamily of glycosyltransferases (2003) (219)
- FtsW is a peptidoglycan polymerase that is functional only in complex with its cognate penicillin-binding protein (2018) (183)
- Remarkable structural similarities between diverse glycosyltransferases. (2002) (168)
- A small molecule that inhibits OGT activity in cells. (2015) (159)
- Crystal structure of a peptidoglycan glycosyltransferase suggests a model for processive glycan chain synthesis (2007) (151)
- Envelope Structures of Gram-Positive Bacteria. (2017) (146)
- HCF-1 Is Cleaved in the Active Site of O-GlcNAc Transferase (2013) (143)
- MreB filaments align along greatest principal membrane curvature to orient cell wall synthesis (2018) (137)
- Better substrates for bacterial transglycosylases. (2001) (134)
- Discovery of a small molecule that blocks wall teichoic acid biosynthesis in Staphylococcus aureus. (2009) (129)
- Moenomycin family antibiotics: chemical synthesis, biosynthesis, and biological activity. (2010) (127)
- Chemistry and biology of ramoplanin: a lipoglycodepsipeptide with potent antibiotic activity. (2005) (123)
- Discovery of wall teichoic acid inhibitors as potential anti-MRSA β-lactam combination agents. (2013) (122)
- The mechanism of action of ramoplanin and enduracidin. (2006) (122)
- Vancomycin analogues active against vanA-resistant strains inhibit bacterial transglycosylase without binding substrate (2003) (119)
- Genes Contributing to Staphylococcus aureus Fitness in Abscess- and Infection-Related Ecologies (2014) (119)
- A revised pathway proposed for Staphylococcus aureus wall teichoic acid biosynthesis based on in vitro reconstitution of the intracellular steps. (2008) (118)
- The Biochemistry of O-GlcNAc Transferase: Which Functions Make It Essential in Mammalian Cells? (2016) (117)
- Structural snapshots of the reaction coordinate for O-GlcNAc transferase (2012) (114)
- Transpeptidase-mediated incorporation of D-amino acids into bacterial peptidoglycan. (2011) (106)
- A streamlined metabolic pathway for the biosynthesis of moenomycin A. (2007) (100)
- Ramoplanin inhibits bacterial transglycosylases by binding as a dimer to lipid II. (2003) (95)
- Late-Stage Polyribitol Phosphate Wall Teichoic Acid Biosynthesis in Staphylococcus aureus (2008) (90)
- Detection of Lipid-Linked Peptidoglycan Precursors by Exploiting an Unexpected Transpeptidase Reaction (2014) (90)
- Structure-Based Evolution of Low Nanomolar O-GlcNAc Transferase Inhibitors. (2018) (85)
- Reconstitution of Peptidoglycan Cross-Linking Leads to Improved Fluorescent Probes of Cell Wall Synthesis (2014) (85)
- Lipid II overproduction allows direct assay of transpeptidase inhibition by β-lactams (2017) (82)
- Analysis of Glycan Polymers Produced by Peptidoglycan Glycosyltransferases* (2007) (81)
- A Neutral Diphosphate Mimic Crosslinks the Active Site of Human O-GlcNAc Transferase (2011) (81)
- Teichoic acid biosynthesis as an antibiotic target. (2013) (81)
- Maturing Mycobacterium smegmatis peptidoglycan requires non-canonical crosslinks to maintain shape (2018) (81)
- Identification of selective inhibitors for the glycosyltransferase MurG via high-throughput screening. (2004) (80)
- Structure of the peptidoglycan polymerase RodA resolved by evolutionary coupling analysis (2018) (80)
- Intrinsic lipid preferences and kinetic mechanism of Escherichia coli MurG. (2002) (79)
- A central role for PBP2 in the activation of peptidoglycan polymerization by the bacterial cell elongation machinery (2018) (78)
- A new platform for ultra-high density Staphylococcus aureus transposon libraries (2015) (78)
- An Antibiotic That Inhibits a Late Step in Wall Teichoic Acid Biosynthesis Induces the Cell Wall Stress Stimulon in Staphylococcus aureus (2012) (78)
- The Kinetic Characterization of Escherichia coli MurG Using Synthetic Substrate Analogues (1999) (77)
- Genome-wide screen for genes involved in eDNA release during biofilm formation by Staphylococcus aureus (2017) (76)
- Decoupling catalytic activity from biological function of the ATPase that powers lipopolysaccharide transport (2014) (75)
- Lipid-linked cell wall precursors regulate membrane association of bacterial actin MreB (2014) (74)
- Identification of active-site inhibitors of MurG using a generalizable, high-throughput glycosyltransferase screen. (2003) (73)
- A New Mechanism of Action Proposed for Ramoplanin (2000) (73)
- Compound-gene interaction mapping reveals distinct roles for Staphylococcus aureus teichoic acids (2014) (72)
- Lipoprotein activators stimulate Escherichia coli penicillin-binding proteins by different mechanisms. (2014) (72)
- The direction of glycan chain elongation by peptidoglycan glycosyltransferases. (2007) (68)
- Substrate Synthesis and Activity Assay for MurG (1998) (68)
- Structural analysis of the contacts anchoring moenomycin to peptidoglycan glycosyltransferases and implications for antibiotic design. (2008) (67)
- Synthesis of heptaprenyl-lipid IV to analyze peptidoglycan glycosyltransferases. (2007) (65)
- In vitro reconstitution of two essential steps in wall teichoic acid biosynthesis. (2006) (65)
- O-Linked N-Acetylglucosaminyltransferase Inhibition Prevents G2/M Transition in Xenopus laevis Oocytes* (2007) (64)
- A synthetic lethal approach for compound and target identification in Staphylococcus aureus (2015) (61)
- A strategy to discover inhibitors of O-linked glycosylation. (2008) (61)
- Structural coordination of polymerization and crosslinking by a SEDS-bPBP peptidoglycan synthase complex (2020) (61)
- Complete characterization of the seventeen step moenomycin biosynthetic pathway. (2009) (59)
- Development of improved inhibitors of wall teichoic acid biosynthesis with potent activity against Staphylococcus aureus. (2010) (59)
- ABC transporters required for export of wall teichoic acids do not discriminate between different main chain polymers. (2011) (58)
- Bacterial transglycosylase inhibitors. (2005) (58)
- The Mechanism of Action of Lysobactin. (2016) (57)
- In vitro reconstitution demonstrates the cell wall ligase activity of LCP proteins. (2017) (57)
- Sugars as DNA binders: a comment on the calicheamicin oligosaccharide (1990) (56)
- Structural characterization of a calicheamicin-DNA complex by NMR (1993) (56)
- Genetic factors that influence moenomycin production in streptomycetes (2010) (54)
- The role of the substrate lipid in processive glycan polymerization by the peptidoglycan glycosyltransferases. (2010) (54)
- O-GlcNAc Transferase Recognizes Protein Substrates Using an Asparagine Ladder in the Tetratricopeptide Repeat (TPR) Superhelix. (2018) (54)
- Moenomycin resistance mutations in Staphylococcus aureus reduce peptidoglycan chain length and cause aberrant cell division. (2014) (53)
- Haloduracin α Binds the Peptidoglycan Precursor Lipid II with 2:1 Stoichiometry (2011) (53)
- Staphylococcus aureus and Bacillus subtilis W23 make polyribitol wall teichoic acids using different enzymatic pathways. (2010) (52)
- Pleiotropic regulatory genes bldA, adpA and absB are implicated in production of phosphoglycolipid antibiotic moenomycin (2013) (52)
- Substrate analogues to study cell-wall biosynthesis and its inhibition. (2002) (50)
- High OGT activity is essential for MYC-driven proliferation of prostate cancer cells (2019) (49)
- The Making of a Sweet Modification: Structure and Function of O-GlcNAc Transferase* (2014) (49)
- Structural characterization of the O-GlcNAc cycling enzymes: insights into substrate recognition and catalytic mechanisms. (2019) (49)
- Kinetic Characterization of the Glycosyltransferase Module of Staphylococcus aureus PBP2 (2005) (48)
- Uncovering the activities, biological roles, and regulation of bacterial cell wall hydrolases and tailoring enzymes (2020) (47)
- Genome-wide mutant profiling predicts the mechanism of a Lipid II binding antibiotic (2018) (46)
- Multi-strain Tn-Seq reveals common daptomycin resistance determinants in Staphylococcus aureus (2019) (46)
- In vitro reconstitution of EryCIII activity for the preparation of unnatural macrolides. (2005) (44)
- Forming cross-linked peptidoglycan from synthetic gram-negative Lipid II. (2013) (44)
- O-GlcNAc regulates gene expression by controlling detained intron splicing (2020) (44)
- Identification of a Functionally Unique Family of Penicillin-Binding Proteins. (2017) (44)
- Multidrug Intrinsic Resistance Factors in Staphylococcus aureus Identified by Profiling Fitness within High-Diversity Transposon Libraries (2016) (43)
- Isolated peptidoglycan glycosyltransferases from different organisms produce different glycan chain lengths. (2008) (43)
- Aspartate residues far from the active site drive O-GlcNAc transferase substrate selection. (2019) (41)
- Acceptor substrate selectivity and kinetic mechanism of Bacillus subtilis TagA. (2006) (41)
- Synthesis of mono- and disaccharide analogs of moenomycin and lipid II for inhibition of transglycosylase activity of penicillin-binding protein 1b. (2004) (41)
- E. Coli MurG: a paradigm for a superfamily of glycosyltransferases. (2001) (41)
- Coordination of export and glycosylation of landomycins in Streptomyces cyanogenus S136. (2008) (39)
- In Vitro Antimicrobial Activity of Wall Teichoic Acid Biosynthesis Inhibitors against Staphylococcus aureus Isolates (2010) (38)
- Tuning the moenomycin pharmacophore to enable discovery of bacterial cell wall synthesis inhibitors. (2013) (38)
- Development and Characterization of Potent Cyclic Acyldepsipeptide Analogues with Increased Antimicrobial Activity. (2016) (37)
- Analysis of Hydroxylamine Glycosidic Linkages: Structural Consequences of the NO Bond in Calicheamicin (1994) (37)
- Reconstitution of Staphylococcus aureus Lipoteichoic Acid Synthase Activity Identifies Congo Red as a Selective Inhibitor. (2018) (36)
- Wall teichoic acid protects Staphylococcus aureus from inhibition by Congo red and other dyes. (2012) (35)
- Differential inhibition of Staphylococcus aureus PBP2 by glycopeptide antibiotics. (2005) (35)
- Peptidoglycan Cross-Linking Preferences of Staphylococcus aureus Penicillin-Binding Proteins Have Implications for Treating MRSA Infections. (2017) (35)
- Streptomyces ghanaensis pleiotropic regulatory gene wblAgh influences morphogenesis and moenomycin production (2011) (34)
- Expression and characterization of the isolated glycosyltransferase module of Escherichia coli PBP1b. (2004) (34)
- Microarray Discovery of New OGT Substrates: The Medulloblastoma Oncogene OTX2 Is O-GlcNAcylated (2014) (33)
- Cofactor bypass variants reveal a conformational control mechanism governing cell wall polymerase activity (2016) (32)
- Rethinking ramoplanin: the role of substrate binding in inhibition of peptidoglycan biosynthesis. (2002) (32)
- Dissecting ramoplanin: mechanistic analysis of synthetic ramoplanin analogues as a guide to the design of improved antibiotics. (2004) (31)
- Characterization of rhodosaminyl transfer by the AknS/AknT glycosylation complex and its use in reconstituting the biosynthetic pathway of aclacinomycin A. (2007) (31)
- NMR characterization of calicheamicin γ1I bound to DNA (1994) (31)
- Non-proteinogenic Amino Acids in Lacticin 481 Analogues Result in More Potent Inhibition of Peptidoglycan Transglycosylation (2012) (31)
- Primer preactivation of peptidoglycan polymerases. (2011) (31)
- Modular synthesis of diphospholipid oligosaccharide fragments of the bacterial cell wall and their use to study the mechanism of moenomycin and other antibiotics. (2011) (30)
- Membrane Potential Is Required for MurJ Function. (2018) (30)
- Studying a cell division amidase using defined peptidoglycan substrates. (2009) (30)
- Functional and structural analysis of a key region of the cell wall inhibitor moenomycin. (2010) (29)
- A partial reconstitution implicates DltD in catalyzing lipoteichoic acid d-alanylation (2018) (28)
- Staphylococcus aureus cell growth and division are regulated by an amidase that trims peptides from uncrosslinked peptidoglycan (2019) (28)
- RNA polymerase mutations cause cephalosporin resistance in clinical Neisseria gonorrhoeae isolates (2019) (28)
- Mammalian cell proliferation requires noncatalytic functions of O-GlcNAc transferase (2020) (28)
- Enabling Glycosyltransferase Evolution: A Facile Substrate‐Attachment Strategy for Phage‐Display Enzyme Evolution (2006) (27)
- Mode of action and structure–activity relationship studies of geobacillin I (2013) (27)
- Conformational analysis of the nitrogen-oxygen bond in the calicheamicin oligosaccharide (1991) (27)
- Role of wall teichoic acids in Staphylococcus aureus endophthalmitis. (2011) (26)
- How the glycosyltransferase OGT catalyzes amide bond cleavage (2016) (24)
- Identification and characterization of Streptomyces ghanaensis ATCC14672 integration sites for three actinophage-based plasmids. (2009) (24)
- Substrate Preferences Establish the Order of Cell Wall Assembly in Staphylococcus aureus. (2018) (24)
- HCF-1 Regulates De Novo Lipogenesis through a Nutrient-Sensitive Complex with ChREBP. (2019) (22)
- Inhibition of O-GlcNAc Transferase Renders Prostate Cancer Cells Dependent on CDK9 (2020) (22)
- Inhibition of O-Linked N-Acetylglucosamine Transferase Reduces Replication of Herpes Simplex Virus and Human Cytomegalovirus (2015) (21)
- Functional and biochemical analysis of a key series of ramoplanin analogues. (2009) (20)
- Identification and characterization of the Streptomyces globisporus 1912 regulatory gene lndYR that affects sporulation and antibiotic production. (2011) (20)
- High‐throughput transposon sequencing highlights the cell wall as an important barrier for osmotic stress in methicillin resistant Staphylococcus aureus and underlines a tailored response to different osmotic stressors (2019) (20)
- Accelerating the discovery of antibacterial compounds using pathway-directed whole cell screening. (2016) (20)
- Two distinct mechanisms for TIM barrel prenyltransferases in bacteria. (2011) (19)
- FtsW is a peptidoglycan polymerase that is activated by its cognate penicillin-binding protein (2018) (18)
- Chemical tools to characterize peptidoglycan synthases. (2019) (18)
- The Length of Lipoteichoic Acid Polymers Controls Staphylococcus aureus Cell Size and Envelope Integrity (2020) (18)
- CDK9 Inhibition Induces a Metabolic Switch that Renders Prostate Cancer Cells Dependent on Fatty Acid Oxidation (2019) (18)
- ABC transporter genes from Streptomyces ghanaensis moenomycin biosynthetic gene cluster: roles in antibiotic production and export (2012) (16)
- Reconstitution and characterization of a new desosaminyl transferase, EryCIII, from the erythromycin biosynthetic pathway. (2004) (16)
- Detection of transport intermediates in the peptidoglycan flippase MurJ identifies residues essential for conformational cycling. (2020) (16)
- Novel protein acetyltransferase, Rv2170, modulates carbon and energy metabolism in Mycobacterium tuberculosis (2017) (16)
- Pathway-Directed Screen for Inhibitors of the Bacterial Cell Elongation Machinery (2018) (15)
- Antibiotic That Inhibits the ATPase Activity of an ATP-Binding Cassette Transporter by Binding to a Remote Extracellular Site. (2017) (15)
- An ABC transporter encoding gene lndW confers resistance to landomycin E (2008) (15)
- Proton-dependent transporter gene lndJ confers resistance to landomycin E in Streptomyces globisporus 1912 (2007) (14)
- The direction of chain growth and substrate preferences of SEDS-family peptidoglycan glycosyltransferases. (2019) (14)
- Antibiotic Combinations That Enable One-Step, Targeted Mutagenesis of Chromosomal Genes. (2018) (14)
- MoeH5: a natural glycorandomizer from the moenomycin biosynthetic pathway (2013) (13)
- Bacterial Cell Wall Components (2008) (13)
- A gene cluster for the biosynthesis of moenomycin family antibiotics in the genome of teicoplanin producer Actinoplanes teichomyceticus (2016) (12)
- Properties of lanK-based regulatory circuit involved in landomycin biosynthesis in Streptomyces cyanogenus S136 (2010) (12)
- Protein substrates engage the lumen of O-GlcNac transferase’s tetratricopeptide repeat domain in different ways (2020) (12)
- Biochemical reconstitution defines new functions for membrane-bound glycosidases in assembly of the bacterial cell wall (2021) (11)
- Calicheamicin−DNA Recognition: An Analysis of Seven Different Drug−DNA Complexes (2000) (11)
- Gene ssfg_01967 (miaB) for tRNA modification influences morphogenesis and moenomycin biosynthesis in Streptomyces ghanaensis ATCC14672. (2019) (11)
- Aspartate Glycosylation Triggers Isomerization to Isoaspartate. (2017) (11)
- Chemistry and Biology of Ramoplanin: A Lipoglycodepsipeptide with Potent Antibiotic Activity (2005) (10)
- High-throughput transposon sequencing highlights the cell wall as an important barrier for osmotic stress in methicillin resistant Staphylococcus aureus and underlines a tailored response to different osmotic stressors (2019) (10)
- Exposure of Staphylococcus aureus to Targocil Blocks Translocation of the Major Autolysin Atl across the Membrane, Resulting in a Significant Decrease in Autolysis (2018) (10)
- Transcriptional regulators of GntR family in Streptomyces coelicolor A3(2): analysis in silico and in vivo of YtrA subfamily (2016) (10)
- Lipoteichoic acid polymer length is determined by competition between free starter units (2020) (9)
- Generation and study of the strains of streptomycetes-heterologous hosts for the production of moenomycin (2014) (9)
- MreB Filaments Create Rod Shape By Aligning Along Principal Membrane Curvature (2017) (8)
- Testing the utility of site-specific recombinases for manipulations of genome of moenomycin producer Streptomyces ghanaensis ATCC14672 (2015) (8)
- Structure and reconstitution of a hydrolase complex that may release peptidoglycan from the membrane after polymerization (2020) (8)
- Comparative Tn-Seq reveals common daptomycin resistance determinants in Staphylococcus aureus despite strain-dependent differences in essentiality of shared cell envelope genes (2019) (6)
- Bacillus anthracis Responds to Targocil-Induced Envelope Damage through EdsRS Activation of Cardiolipin Synthesis (2020) (5)
- Rapid Inhibitor Discovery by Exploiting Synthetic Lethality (2022) (5)
- Maturing Mycobacterial Peptidoglycan Requires Non-canonical Crosslinks to Maintain Shape (2018) (5)
- Genes for biosynthesis of butenolide-like signalling molecules in Streptomyces ghanaensis, their role in moenomycin production (2014) (5)
- Natural products that target the cell envelope. (2021) (5)
- Cleavage behavior of calicheamicin y1 and calicheamicin T (2004) (5)
- An activation pathway governs cell wall polymerization by a bacterial morphogenic machine (2018) (4)
- The cell cycle in Staphylococcus aureus is regulated by an amidase that controls peptidoglycan synthesis (2019) (4)
- Coordination of bacterial cell wall and outer membrane biosynthesis (2023) (3)
- Biofilm Formation by Staphylococcus aureus is Triggered by a Drop in the Levels of the Second Messenger cyclic-di-AMP (2020) (3)
- CRYSTAL STRUCTURE OF MURG:GLCNAC COMPLEX (2003) (3)
- Author response: MreB filaments align along greatest principal membrane curvature to orient cell wall synthesis (2018) (3)
- Structure and reconstitution of a hydrolase complex that may release peptidoglycan from the membrane after polymerization (2020) (3)
- Faculty Opinions recommendation of The shared antibiotic resistome of soil bacteria and human pathogens. (2012) (2)
- Pharmacology of bacterial and mycobacterial infections: Cell wall synthesis (2012) (2)
- TN5-BASED TRANSPOSON MUTAGENESIS OF STREPTOMYCES GHANAENSIS ATCC14672: SEARCHING FOR NOVEL REGULATORS OF MOENOMYCIN PRODUCTION (2020) (2)
- O-GlcNAc transferase recognizes protein substrates using an asparagine ladder in the TPR superhelix (2018) (2)
- Structure and function of the SEDS:bPBP bacterial cell wall synthesis machinery (2018) (2)
- Generation and study of the strains of streptomycetes-heterologous hosts for the production of moenomycin (2014) (1)
- CDK 9 Inhibition Induces a Metabolic Switch that Renders Prostate Cancer Cells Dependent on Fatty Acid Oxidation (2019) (1)
- Faculty Opinions recommendation of Aminopyrazinamides: novel and specific GyrB inhibitors that kill replicating and nonreplicating Mycobacterium tuberculosis. (2013) (1)
- Metal cofactor stabilization by a partner protein is a widespread strategy employed for amidase activation (2022) (1)
- THE 1.9 ANGSTROM CRYSTAL STRUCTURE OF E. COLI MURG (2000) (1)
- Allosteric activation of cell wall synthesis during bacterial growth (2022) (1)
- Correction to “Discovery of O-GlcNAc Transferase Inhibitors” (2014) (1)
- Faculty Opinions recommendation of Impact of temperature on the time required for the establishment of primordial biochemistry, and for the evolution of enzymes. (2011) (1)
- Coordinationof export andglycosylationof landomycins in Streptomyces cyanogenus S 136 (2008) (1)
- Author response: Maturing Mycobacterium smegmatis peptidoglycan requires non-canonical crosslinks to maintain shape (2018) (0)
- Faculty Opinions recommendation of Rhomboid distorts lipids to break the viscosity-imposed speed limit of membrane diffusion. (2019) (0)
- Faculty Opinions recommendation of Functional expression of O-linked GlcNAc transferase. Domain structure and substrate specificity. (2001) (0)
- Faculty Opinions recommendation of Lysozyme Counteracts β-Lactam Antibiotics by Promoting the Emergence of L-Form Bacteria. (2018) (0)
- Efficacy of Wall Teichoic Acid Biosynthesis Inhibitor in Ocular Infection Caused by Staphylococcus Aureus (2010) (0)
- Crystal Structure of human O-GlcNAc Transferase bound to a peptide from HCF-1 pro-repeat2(1-26) and UDP-GlcNAc (2014) (0)
- Faculty Opinions recommendation of Restoring methicillin-resistant Staphylococcus aureus susceptibility to β-lactam antibiotics. (2013) (0)
- A Time-Resolved FRET Assay Identifies a Small Molecule that Inhibits the Essential Bacterial Cell Wall Polymerase FtsW. (2023) (0)
- Faculty Opinions recommendation of Structure of Enterococcus faeciuml,d-transpeptidase acylated by ertapenem provides insight into the inactivation mechanism. (2013) (0)
- Crystal structure of Aquifex Aeolicus Peptidoglycan Glycosyltransferase in complex with Decarboxylated Neryl Moenomycin (2011) (0)
- Targeting Wall Teichoic Acids Byosynthesis in Ocular Infection (2009) (0)
- Crystal structure of a selenomethionine derivative of E. coli LptB in complex with ADP-Magensium (2014) (0)
- Structural Insights into O‐GlcNAc Transferase (2013) (0)
- Faculty Opinions recommendation of Epitope recognition of antibodies against a Yersinia pestis lipopolysaccharide trisaccharide component. (2014) (0)
- Crystal structure of Aquifex aeolicus peptidoglycan glycosyltransferase in complex with Methylphosphoryl Neryl Moenomycin (2011) (0)
- The Split Personality of Human O‐GlcNAc Transferase (2015) (0)
- A H 7 N 9 Viruses Preferential Recognition of Avian-Like Receptors in Human Influenza (2013) (0)
- Glycosylation of wall teichoic acid is crucial for host-pathogen interaction and methicillin resistance in Staphylococcus aureus. (2012) (0)
- Membrane Curvature to Orient Cell Wall Synthesis 1 2 (2018) (0)
- A new platform for ultra-high density Staphylococcus aureus transposon libraries (2015) (0)
- Faculty Opinions recommendation of Recruitment of O-GlcNAc transferase to promoters by corepressor mSin3A: coupling protein O-GlcNAcylation to transcriptional repression. (2002) (0)
- Crystal Structure of human O-GlcNAc transferase bound to a peptide from HCF-1 pro-repeat 2 (1-26)E10A (2014) (0)
- Identification of FacZ as a division site placement factor in Staphylococcus aureus (2023) (0)
- Contemporary issues in NSCLC. (2012) (0)
- Faculty Opinions recommendation of Environmental fatty acids enable emergence of infectious Staphylococcus aureus resistant to FASII-targeted antimicrobials. (2017) (0)
- Crystal structure of human O-GlcNAc Transferase with UDP and a thioglycopeptide (2012) (0)
- Structure of an O-GlcNAc transferase point mutant, D554N in complex with peptide (2016) (0)
- Crystal Structure of human O-GlcNAc Transferase bound to a peptide from HCF-1 pro-repeat2(1-26)E10Q and UDP-5SGlcNAc (2014) (0)
- Faculty Opinions recommendation of A processive carbohydrate polymerase that mediates bifunctional catalysis using a single active site. (2012) (0)
- Faculty Opinions recommendation of Structure-based design of beta 1,4-galactosyltransferase I (beta 4Gal-T1) with equally efficient N-acetylgalactosaminyltransferase activity: point mutation broadens beta 4Gal-T1 donor specificity. (2002) (0)
- Faculty Opinions recommendation of A methylaspartate cycle in haloarchaea. (2011) (0)
- Faculty Opinions recommendation of Novel determinants of antibiotic resistance: identification of mutated loci in highly methicillin-resistant subpopulations of methicillin-resistant Staphylococcus aureus. (2014) (0)
- Faculty Opinions recommendation of Rethinking molecular similarity: comparing compounds on the basis of biological activity. (2012) (0)
- Genes for biosynthesis of butenolide-like signalling molecules in Streptomyces ghanaensis, their role in moenomycin production (2014) (0)
- Faculty Opinions recommendation of Artificial photosynthetic cell producing energy for protein synthesis. (2019) (0)
- Crystal structure of E. coli LptB in complex with ADP-magnesium (2014) (0)
- Faculty Opinions recommendation of Examination of bacterial inhibition using a catalytic DNA. (2014) (0)
- Abstract 1579: A common strategy for bacterial cell envelope polymer acylation involves a multi-enzyme cascade of covalent intermediates (2023) (0)
- Development of protein microarray tools for the ex vivo profiling of O‐linked N‐acetylglucosamine transferase (OGT) substrates (2013) (0)
- Annual Review of Biochemistry (1940) (0)
- Genome-wide screen for genes involved in eDNA release during biofilm formation by (2017) (0)
- Structural coordination of polymerization and crosslinking by a SEDS–bPBP peptidoglycan synthase complex (2020) (0)
- TagT bound to LIIa-WTA (2018) (0)
- Combining Signal Peptidase and Lipoprotein Processing Inhibitors Overcomes Ayr Resistance in Staphylococcus aureus (2023) (0)
- Crystal structure of human O-GlcNAc Transferase with UDP-5SGlcNAc and a peptide substrate (2012) (0)
- Crystal structure of E. coli LptB-E163Q in complex with ATP-sodium (2014) (0)
- A gene cluster for the biosynthesis of moenomycin family antibiotics in the genome of teicoplanin producer Actinoplanes teichomyceticus (2016) (0)
- Faculty Opinions recommendation of Molecular and phenotypic analysis of CaVRG4, encoding an essential Golgi apparatus GDP-mannose transporter. (2002) (0)
- Faculty Opinions recommendation of A Hidden Markov Model for identifying essential and growth-defect regions in bacterial genomes from transposon insertion sequencing data. (2013) (0)
- Analogues de vancomycine (2001) (0)
- High-throughput transposon sequencing highlights the cell wall as an important barrier for salt stress in methicillin resistant Staphylococcus aureus (2019) (0)
- In Vitro Antimicrobial Activity of Wall Teichoic Acid Biosynthesis Inhibitors against Staphylococcus aureus Isolates (cid:1) † (2011) (0)
- Faculty Opinions recommendation of The nonantibiotic small molecule cyslabdan enhances the potency of β-lactams against MRSA by inhibiting pentaglycine interpeptide bridge synthesis. (2012) (0)
- O-GlcNAc transferase maintains metabolic homeostasis in response to CDK9 inhibition (2022) (0)
- Faculty Opinions recommendation of Two unique phosphorylation-driven signaling pathways crosstalk in Staphylococcus aureus to modulate the cell-wall charge: Stk1/Stp1 meets GraSR. (2013) (0)
- ABC transporter genes from Streptomyces ghanaensis moenomycin biosynthetic gene cluster: roles in antibiotic production and export (2012) (0)
- Faculty Opinions recommendation of Metabolic footprinting of mutant libraries to map metabolite utilization to genotype. (2013) (0)
- Faculty Opinions recommendation of Silver enhances antibiotic activity against gram-negative bacteria. (2013) (0)
- Crystal structure of a complex of the peptidoglycan glycosyltransferase domain from Aquifex aeolicus and neryl moenomycin A (2008) (0)
- DNA-Binding Glycoconjugates (2000) (0)
- Crystal structure of human O-GlcNAc transferase bound to a peptide from HCF-1 pro-repeat 2 (11-26) and inhibitor 4a (2018) (0)
- Faculty Opinions recommendation of Selective penicillin-binding protein imaging probes reveal substructure in bacterial cell division. (2012) (0)
- Crystal structure of human O-GlcNAc transferase bound to a peptide from HCF-1 pro-repeat 2 (11-26) (2014) (0)
- Crystal structure of human O-GlcNAc Transferase in complex with UDP and a glycopeptide (2012) (0)
- Faculty Opinions recommendation of Mode of action, in vitro activity, and in vivo efficacy of AFN-1252, a selective antistaphylococcal FabI inhibitor. (2012) (0)
- Novel protein acetyltransferase, Rv2170, modulates carbon and energy metabolism in Mycobacterium tuberculosis (2017) (0)
- Crystal structure of a peptidoglycan glycosyltransferase from a class A PBP: insight into bacterial cell wall synthesis (2007) (0)
- Crystal Structure of N. meningitidis ClpP in complex with agonist ADEP A54556. (2016) (0)
- Crystal structure of human O-GlcNAc Transferase with UDP-5SGlcNAc (2012) (0)
- Faculty Opinions recommendation of A novel post-translational modification in nerve terminals: O-linked N-acetylglucosamine phosphorylation. (2011) (0)
- FtsW is a peptidoglycan polymerase that is functional only in complex with its cognate penicillin-binding protein (2019) (0)
- Glycosylation of Unreactive Substrates. (1989) (0)
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