Svein Valla
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Norwegian molecular biologist
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Molecular Biology
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Why Is Svein Valla Influential?
(Suggest an Edit or Addition)According to Wikipedia, Svein Valla was a Norwegian molecular biologist. He was a professor of microbial molecular biology at the Norwegian University of Science and Technology and fellow of the Norwegian Academy of Science and Letters.
Svein Valla's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Bacterial alginates: biosynthesis and applications (1997) (302)
- Construction and use of a versatile set of broad-host-range cloning and expression vectors based on the RK2 replicon (1997) (260)
- Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway. (2000) (235)
- Genome Sequence of Azotobacter vinelandii, an Obligate Aerobe Specialized To Support Diverse Anaerobic Metabolic Processes (2009) (221)
- Biosynthesis and applications of alginates (1998) (209)
- Improved broad-host-range RK2 vectors useful for high and low regulated gene expression levels in gram-negative bacteria. (1997) (178)
- A new gene required for cellulose production and a gene encoding cellulolytic activity in Acetobacter xylinum are colocalized with the bcs operon (1994) (164)
- The Pseudomonas fluorescens AlgG Protein, but Not Its Mannuronan C-5-Epimerase Activity, Is Needed for Alginate Polymer Formation (2003) (146)
- A family of modular type mannuronan C‐5‐epimerase genes controls alginate structure in Azotobacter vinelandii (1995) (144)
- The Presence of N-Terminal Secretion Signal Sequences Leads to Strong Stimulation of the Total Expression Levels of Three Tested Medically Important Proteins during High-Cell-Density Cultivations of Escherichia coli (2006) (115)
- Cloning and expression of an Azotobacter vinelandii mannuronan C-5-epimerase gene (1994) (114)
- In Vivo Analysis of the Regulatory Genes in the Nystatin Biosynthetic Gene Cluster of Streptomyces noursei ATCC 11455 Reveals Their Differential Control Over Antibiotic Biosynthesis (2004) (103)
- A comparative analysis of the properties of regulated promoter systems commonly used for recombinant gene expression in Escherichia coli (2013) (103)
- Cloning and Expression of Three NewAzotobacter vinelandii Genes Closely Related to a Previously Described Gene Family Encoding Mannuronan C-5-Epimerases (1999) (96)
- Broad-Host-Range Plasmid pJB658 Can Be Used for Industrial-Level Production of a Secreted Host-Toxic Single-Chain Antibody Fragment in Escherichia coli (2004) (90)
- Mannuronan C-5-epimerases and their application for in vitro and in vivo design of new alginates useful in biotechnology. (1999) (89)
- New broad-host-range promoter probe vectors based on the plasmid RK2 replicon. (2001) (89)
- Role of the Pseudomonas fluorescens Alginate Lyase (AlgL) in Clearing the Periplasm of Alginates Not Exported to the Extracellular Environment (2005) (87)
- Cellulose-negative Mutants of Acetobacter xylinum (1982) (86)
- AlgX Is a Periplasmic Protein Required for Alginate Biosynthesis in Pseudomonas aeruginosa (2004) (86)
- A new Azotobacter vinelandii mannuronan C-5-epimerase gene (algG) is part of an alg gene cluster physically organized in a manner similar to that in Pseudomonas aeruginosa (1996) (84)
- Ionic and acid gel formation of epimerised alginates; the effect of AlgE4. (2000) (83)
- Metagenomics of microbial life in extreme temperature environments. (2013) (82)
- Positively regulated bacterial expression systems (2008) (81)
- The dual roles of AlgG in C‐5‐epimerization and secretion of alginate polymers in Pseudomonas aeruginosa (2003) (77)
- The Recombinant Azotobacter vinelandii Mannuronan C-5-Epimerase AlgE4 Epimerizes Alginate by a Nonrandom Attack Mechanism* (1999) (76)
- A plasmid RK2-based broad-host-range cloning vector useful for transfer of metagenomic libraries to a variety of bacterial species. (2009) (76)
- Plasmid-Dependent Methylotrophy in Thermotolerant Bacillus methanolicus (2004) (75)
- Characterization of Three New Azotobacter vinelandii Alginate Lyases, One of Which Is Involved in Cyst Germination (2009) (70)
- The Catalytic Activities of the Bifunctional Azotobacter vinelandii Mannuronan C-5-Epimerase and Alginate Lyase AlgE7 Probably Originate from the Same Active Site in the Enzyme* (2001) (66)
- Cloning of a gene involved in cellulose biosynthesis in Acetobacter xylinum: Complementation of cellulose-negative mutants by the UDPG pyrophosphorylase structural gene (1989) (66)
- Hexuronyl C5-epimerases in alginate and glycosaminoglycan biosynthesis. (2001) (65)
- Biochemical Properties and Substrate Specificities of a Recombinantly Produced Azotobacter vinelandiiAlginate Lyase (1998) (64)
- High coverage sequencing of DNA from microorganisms living in an oil reservoir 2.5 kilometres subsurface. (2011) (60)
- A New and Improved Host-Independent Plasmid System for RK2-Based Conjugal Transfer (2014) (60)
- Identification of a gene cluster for antibacterial polyketide-derived antibiotic biosynthesis in the nystatin producer Streptomyces noursei ATCC 11455. (2000) (58)
- Isolation and characterization of marine pigmented bacteria from Norwegian coastal waters and screening for carotenoids with UVA-blue light absorbing properties (2010) (58)
- Random Mutagenesis of the Pm Promoter as a Powerful Strategy for Improvement of Recombinant-Gene Expression (2009) (55)
- Upregulated Transcription of Plasmid and Chromosomal Ribulose Monophosphate Pathway Genes Is Critical for Methanol Assimilation Rate and Methanol Tolerance in the Methylotrophic Bacterium Bacillus methanolicus (2006) (53)
- Mannuronan C-5 epimerases and cellular differentiation of Azotobacter vinelandii. (2000) (52)
- The microbial communities in two apparently physically separated deep subsurface oil reservoirs show extensive DNA sequence similarities. (2014) (52)
- Physiological Analysis of the Expression of the Styrene Degradation Gene Cluster in Pseudomonas fluorescensST (2000) (52)
- Overexpression of Wild-Type Aspartokinase Increases l-Lysine Production in the Thermotolerant Methylotrophic Bacterium Bacillus methanolicus (2008) (51)
- Structural and Mutational Characterization of the Catalytic A-module of the Mannuronan C-5-epimerase AlgE4 from Azotobacter vinelandii* (2008) (50)
- The A Modules of the Azotobacter vinelandii Mannuronan-C-5-Epimerase AlgE1 Are Sufficient for both Epimerization and Binding of Ca2+ (1999) (49)
- The expression of recombinant genes in Escherichia coli can be strongly stimulated at the transcript production level by mutating the DNA‐region corresponding to the 5′‐untranslated part of mRNA (2009) (48)
- Parameters affecting gene expression from the Pm promoter in gram-negative bacteria. (2000) (47)
- Upregulated transcription of plasmid and chromosomal ribulose monophosphate pathway genes is critical for methanol assimilation rate and methanol tolerance in the methylotrophic bacterium Bacillus methanolicus. (2006) (45)
- The XylS/Pm regulator/promoter system and its use in fundamental studies of bacterial gene expression, recombinant protein production and metabolic engineering (2017) (43)
- Isolation and characterization of a new extracellular polysaccharide from a cellulose-negative strain of Acetobacter xylinum. (1981) (43)
- NMR Structure of the R-module (2006) (41)
- Molecular cloning and analysis of a pleiotropic regulatory gene locus from the nystatin producer Streptomyces noursei ATCC11455. (1999) (41)
- Pm promoter expression mutants and their use in broad-host-range RK2 plasmid vectors. (2000) (40)
- The Azotobacter vinelandii Mannuronan C-5-Epimerase AlgE1 Consists of Two Separate Catalytic Domains* (1998) (40)
- Hexaene derivatives of nystatin produced as a result of an induced rearrangement within the nysC polyketide synthase gene in S. noursei ATCC 11455. (2002) (37)
- Nucleotide sequence and expression analysis of the Acetobacter xylinum uridine diphosphoglucose pyrophosphorylase gene (1991) (37)
- Isolation of Mutant Alginate Lyases with Cleavage Specificity for Di-guluronic Acid Linkages* (2010) (37)
- The Azotobacter vinelandii AlgE mannuronan C-5-epimerase family is essential for the in vivo control of alginate monomer composition and for functional cyst formation. (2008) (35)
- Identification and Characterization of an Azotobacter vinelandii Type I Secretion System Responsible for Export of the AlgE-Type Mannuronan C-5-Epimerases (2006) (34)
- Construction and analyses of hybrid Azotobacter vinelandii mannuronan C-5 epimerases with new epimerization pattern characteristics. (2004) (33)
- Directed evolution of the transcription factor XylS for development of improved expression systems (2009) (30)
- Mapping global effects of the anti-sigma factor MucA in Pseudomonas fluorescens SBW25 through genome-scale metabolic modeling (2013) (30)
- Mannuronan C-5 epimerases suited for tailoring of specific alginate structures obtained by high-throughput screening of an epimerase mutant library. (2013) (29)
- Combinatorial Mutagenesis and Selection of Improved Signal Sequences and Their Application for High-Level Production of Translocated Heterologous Proteins in Escherichia coli (2012) (28)
- Continuous Control of the Flow in Biochemical Pathways through 5′ Untranslated Region Sequence Modifications in mRNA Expressed from the Broad-Host-Range Promoter Pm (2011) (27)
- In vitro determined kinetic properties of mutant phosphoglucomutases and their effects on sugar catabolism in Escherichia coli. (2000) (27)
- Nucleotide sequence and expression analysis of the Acetobacter xylinum phosphoglucomutase gene. (1994) (27)
- Alginate Biosynthesis Factories in Pseudomonas fluorescens: Localization and Correlation with Alginate Production Level (2015) (27)
- Enzymatic Alginate Modification (2009) (27)
- Structural and Functional Characterization of the R-modules in Alginate C-5 Epimerases AlgE4 and AlgE6 from Azotobacter vinelandii (2014) (26)
- Rapid reagentless quantification of alginate biosynthesis in Pseudomonas fluorescens bacteria mutants using FT-IR spectroscopy coupled to multivariate partial least squares regression (2012) (26)
- The Pseudomonas syringae Genome Encodes a Combined Mannuronan C-5-epimerase and O-Acetylhydrolase, Which Strongly Enhances the Predicted Gel-forming Properties of Alginates* (2004) (25)
- DNA Cloning and Assembly Methods (2014) (25)
- Properties and action pattern of the recombinant mannuronan C-5-epimerase AlgE2 (1999) (24)
- The Acinetobacter sp. chnB promoter together with its cognate positive regulator ChnR is an attractive new candidate for metabolic engineering applications in bacteria. (2008) (23)
- Time-resolved 1H and 13C NMR spectroscopy for detailed analyses of the Azotobacter vinelandii mannuronan C-5 epimerase reaction. (2002) (22)
- Combinatorial Mutagenesis and Selection to Understand and Improve Yeast Promoters (2013) (22)
- Complementation of cellulose-negative mutants of Acetobacter xylinum by the cloned structural gene for phosphoglucomutase (1991) (22)
- Conjugative transfer of the naturally occurring plasmids of Acetobacter xylinum by IncP-plasmid-mediated mobilization (1986) (21)
- Identification of genes affecting alginate biosynthesis in Pseudomonas fluorescens by screening a transposon insertion library (2017) (18)
- Investigating alginate production and carbon utilization in Pseudomonas fluorescens SBW25 using mass spectrometry-based metabolic profiling (2013) (18)
- Exploring the 5'-UTR DNA region as a target for optimizing recombinant gene expression from the strong and inducible Pm promoter in Escherichia coli. (2012) (18)
- Mutational Analyses of Glucose Dehydrogenase and Glucose-6-Phosphate Dehydrogenase Genes in Pseudomonas fluorescens Reveal Their Effects on Growth and Alginate Production (2015) (17)
- Deep Subsurface Oil Reservoirs as Poly-extreme Habitats for Microbial Life. A Current Review (2013) (17)
- The genome sequence of Azotobacter vinelandii , an obligate 1 aerobe specialized to support diverse anaerobic metabolic 2 processes 3 4 running title : Genome sequence of Azotobacter vinelandii 5 6 (2009) (17)
- Species-Dependent Phenotypes of Replication-Temperature-SensitivetrfA Mutants of Plasmid RK2: a Codon-Neutral Base Substitution Stimulates Temperature Sensitivity by Leading to Reduced Levels of trfA Expression (1998) (16)
- Use of protein trans‐splicing to produce active and segmentally 2H, 15N labeled mannuronan C5‐epimerase AlgE4 (2010) (15)
- New insights into Pseudomonas fluorescens alginate biosynthesis relevant for the establishment of an efficient production process for microbial alginates. (2017) (15)
- An experimental study on carbon flow in Escherichia coli as a function of kinetic properties and expression levels of the enzyme phosphoglucomutase. (1998) (15)
- Broad-host-range plasmid vectors for gene expression in bacteria. (2011) (15)
- Heterologous gene expression in Lactococcus lactis; expression of the Azotobacter vinelandii algE6 gene product displaying mannuronan C-5 epimerase activity. (2003) (13)
- Strong stimulation of recombinant protein production in Escherichia coli by combining stimulatory control elements in an expression cassette (2012) (13)
- Design and Optimization of Short DNA Sequences That Can Be Used as 5′ Fusion Partners for High-Level Expression of Heterologous Genes in Escherichia coli (2013) (10)
- Safety in numbers: multiple occurrences of highly similar homologs among Azotobacter vinelandii carbohydrate metabolism proteins probably confer adaptive benefits (2014) (10)
- Regulation of the expression level of transcription factor XylS reveals new functional insight into its induction mechanism at the Pm promoter (2013) (10)
- Ralstonia sp. U2 naphthalene dioxygenase and Comamonas sp. JS765 nitrobenzene dioxygenase show differences in activity towards methylated naphthalenes. (2012) (10)
- ST Pseudomonas fluorescens the Styrene Degradation Gene Cluster in Physiological Analysis of the Expression of (2000) (9)
- The plasmids of acetobacter xylinum and their interaction with the host chromosome (2004) (8)
- NMR assignment of the R-module from the Azotobacter vinelandii Mannuronan C5-epimerase AlgE4 (2005) (8)
- Discovery and Characterization of a Thermostable Esterase from an Oil Reservoir Metagenome (2016) (8)
- Benzoic Acid-Inducible Gene Expression in Mycobacteria (2015) (8)
- Acetobacter xylinum contains several plasmids: Evidence for their involvement in cellulose formation (2004) (8)
- Metagenomic libraries for functional screening (2011) (7)
- Identification of Regulatory Genes and Metabolic Processes Important for Alginate Biosynthesis in Azotobacter vinelandii by Screening of a Transposon Insertion Mutant Library (2020) (6)
- Non-Invasive Analysis of Recombinant mRNA Stability in Escherichia coli by a Combination of Transcriptional Inducer Wash-Out and qRT-PCR (2013) (5)
- Combinatorial engineering for heterologous gene expression (2013) (4)
- NMR assignments of 1H, 13C and 15N resonances of the C-terminal subunit from Azotobacter vinelandii mannuronan C5-epimerase 6 (AlgE6R3) (2010) (4)
- Electrostatic studies of carbohydrate active enzymes (1995) (3)
- Meeting Report: 1st International Functional Metagenomics Workshop May 7–8, 2012, St. Jacobs, Ontario, Canada. (2013) (3)
- RpoS controls the expression and the transport of the AlgE1-7 epimerases in Azotobacter vinelandii (2018) (3)
- 1H, 13C and 15N resonances of the AlgE62 subunit from Azotobacter vinelandii mannuronan C5-epimerase (2010) (3)
- The plasmids of Acetobacter xylinum and their interaction with the host chromosome (1987) (2)
- Overexpression of wild-type aspartokinase increases L-lysine production in methylotrophic Bacillus methanolicus (2008) (2)
- The future is artificial (2009) (1)
- Erratum: A new gene required for cellulose production and a gene encoding cellulolytic activity in Acetobacter xylinum are colocalized with the bcs operon (Journal of Bacteriology 176:3 (665-672)) (1994) (1)
- mannuronan C5-epimerase AlgE4 (2010) (1)
- Increased plasmid copy number allows better utilization of cell resources (2013) (1)
- Azotobacter vinelandii Mannuronan C-5 epimerase AlgE4 A-module complexed with mannuronan trisaccharide (2008) (0)
- Improved expression approach (2007) (0)
- University of Groningen Structural and mutational characterization of the catalytic A-module of the mannuronan C-5- epimerase AlgE4 from Azotobacter vinelandii Rozeboom, (2008) (0)
- Heterologous Genes in Escherichia coli Partners for High-Level Expression of Fusion ' Sequences That Can Be Used as 5 Design and Optimization of Short DNA (2014) (0)
- Improving bacterial recombinant gene expression by separate optimization and combination of two functional parts of 5’-UTR sequences. (2014) (0)
- High coverage sequencing of DNA from ancient microorganisms living at 250 bars 2.5 kilometers subsurface in a Norwegian sea oil reservoir (2011) (0)
- Fine tuning of gene expression in Escherichia coli over five log-factors by using mutations in the 5´- UTR DNA region (2010) (0)
- Production in Escherichia coli of a melanin-like polymer from a marine sediment metagenomic clone expressing rubrerythrin (2011) (0)
- microbial biotechnology (2013) (0)
- Escherichia coli Translocated Heterologous Proteins in Application for High-Level Production of of Improved Signal Sequences and Their Combinatorial Mutagenesis and Selection (2014) (0)
- Identification of genes affecting alginate biosynthesis in Pseudomonas fluorescens by screening a transposon insertion library (2017) (0)
- Issue information (2013) (0)
- New and improved biological tools for conjugal transfer of plasmids (2011) (0)
- Non-invasiveanalysis of mRNA decay rates by a combination of inducer wash‐out and qRTPCR (2012) (0)
- DNA compounds that contain mannuronan C-5-epimerase coding sequences (1995) (0)
- DNA compounds with mannuronan C-5-epimerase coding sequences (1993) (0)
- High-level heterologous protein expression in Esherichia coli by combining mutations in three different regulatory elements (2010) (0)
- Regulation of the expression level of transcription factor XylS reveals new functional insight into its induction mechanism at the Pmpromoter (2013) (0)
- The performance of theXylS/Pm system compared to other commercially available regulator/promotersystems used in bacterial recombinant expression (2012) (0)
- Special Issue: Recombinant Protein Expression in Microorganisms (2019) (0)
- Safety in numbers: multiple occurrences of highly similar homologs among Azotobacter vinelandiicarbohydrate metabolism proteins probably confer adaptive benefits (2014) (0)
- Investigating alginate production and carbon utilization in Pseudomonas fluorescens SBW25 using mass spectrometry-based metabolic profiling (2012) (0)
- Azotobacter vinelandii Mannuronan C-5 epimerase AlgE4 A-module (2008) (0)
- Chemistry and biology: the structure and catalytic mechanism of the mannuronan C-5-epimerase AlgE4 from Azotobacter vinelandii (2008) (0)
- The genetics of cellulose biosynthesis in Acetobacter xylinum (1988) (0)
- Inactivation of the anti-sigma factor MucA causes major perturbations incarbon metabolism in Azotobacter vinelandii (2014) (0)
- IsolationandCharacterization of Marine Pigmented Bacteriafrom NorwegianCoastalWaters and Screening for Carotenoidswith UVA-BlueLight Absorbing Properties § (2010) (0)
- Solution structure of the R-module from AlgE4 (2006) (0)
- A synthetic version of the Pseudomonas putida xylS gene designed for optimal expression in Escherichia coli has a strongly reduced translation efficiency caused by mutations in the 5’ part of the coding sequence (2008) (0)
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