Sydney Brenner | Academic Influence

Why Is Sydney Brenner Influential?

According to Wikipedia, Sydney Brenner was a South African biologist. In 2002, he shared the Nobel Prize in Physiology or Medicine with H. Robert Horvitz and Sir John E. Sulston. Brenner made significant contributions to work on the genetic code, and other areas of molecular biology while working in the Medical Research Council Laboratory of Molecular Biology in Cambridge, England. He established the roundworm Caenorhabditis elegans as a model organism for the investigation of developmental biology, and founded the Molecular Sciences Institute in Berkeley, California, United States.

Sydney Brenner's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Papers

The structure of the nervous system of the nematode Caenorhabditis elegans. (5031)
The genetics of Caenorhabditis elegans. (4821)
DNA Repair and Mutagenesis (3248)
Whole-Genome Shotgun Assembly and Analysis of the Genome of Fugu rubripes (1502)
On the Regulation of DNA Replication in Bacteria (1400)
Gene expression analysis by massively parallel signature sequencing (MPSS) on microbead arrays (1357)
DNA damage and repair (1120)
General Nature of the Genetic Code for Proteins (1091)
The neural circuit for touch sensitivity in Caenorhabditis elegans (977)
The Y-family of DNA polymerases. (823)
An Unstable Intermediate Carrying Information from Genes to Ribosomes for Protein Synthesis (799)
Electron microscopical reconstruction of the anterior sensory anatomy of the nematode caenorhabditis elegans (757)
How nucleotide excision repair protects against cancer (728)
Nondisjunction Mutants of the Nematode CAENORHABDITIS ELEGANS. (725)
The structure of the ventral nerve cord of Caenorhabditis elegans. (631)
Encoded combinatorial chemistry. (580)
p53 modulation of TFIIH–associated nucleotide excision repair activity (571)
DNA repair : a laboratory manual of research procedures (557)
Characterization of the pufferfish (Fugu) genome as a compact model vertebrate genome (557)
Elephant shark genome provides unique insights into gnathostome evolution (553)
Toward a physical map of the genome of the nematode Caenorhabditis elegans. (552)
Fugu genome analysis provides evidence for a whole-genome duplication early during the evolution of ray-finned fishes. (515)
The DNA of Caenorhabditis elegans. (505)
Segmental expression of Hoxb-1 is controlled by a highly conserved autoregulatory loop dependent upon exd/pbx (502)
The SAD1/RAD53 protein kinase controls multiple checkpoints and DNA damage-induced transcription in yeast. (497)
The molecular evolution of genes and proteins: a tale of two serines (476)
Genome 10K: a proposal to obtain whole-genome sequence for 10,000 vertebrate species. (473)
The absence of a pyrimidine dimer repair mechanism in mammalian mitochondria. (462)
The Cockayne syndrome group A gene encodes a WD repeat protein that interacts with CSB protein and a subunit of RNA polymerase II TFIIH (460)
Dopaminergic neurons in the nematode Caenorhabditis elegans (448)
A conserved retinoic acid response element required for early expression of the homeobox gene Hoxb-1 (441)
Specialized DNA Polymerases, Cellular Survival, and the Genesis of Mutations (440)
Model for signal sequence recognition from amino-acid sequence of 54K subunit of signal recognition particle (438)
A genetic locus for the regulation of ribonucleic acid synthesis. (402)
The octopus genome and the evolution of cephalopod neural and morphological novelties (393)
Integrative genome-wide analysis reveals cooperative regulation of alternative splicing by hnRNP proteins. (393)
A Trans-Species Missense SNP in Amhr2 Is Associated with Sex Determination in the Tiger Pufferfish, Takifugu rubripes (Fugu) (391)
Trading places: how do DNA polymerases switch during translesion DNA synthesis? (388)
Amber Suppression: a Nucleotide Change in the Anticodon of a Tyrosine Transfer RNA (354)
Mouse Rev1 protein interacts with multiple DNA polymerases involved in translesion DNA synthesis (347)
UV-induced ubiquitination of RNA polymerase II: a novel modification deficient in Cockayne syndrome cells. (327)
Genetic Code: The ‘Nonsense’ Triplets for Chain Termination and their Suppression (321)
Eukaryotic DNA Polymerases: Proposal for a Revised Nomenclature* (320)
Co-Linearity of the Gene with the Polypeptide Chain (311)
Survey Sequencing and Comparative Analysis of the Elephant Shark (Callorhinchus milii) Genome (308)
Summary statement of the Asilomar conference on recombinant DNA molecules. (300)
Dual roles of a multiprotein complex from S. cerevisiae in transcription and DNA repair (299)
Different forms of TFIIH for transcription and DNA repair: Holo-TFIIH and a nucleotide excision repairosome (283)
Distinct cis-essential modules direct the time-space pattern of the Pax6 gene activity. (283)
Origin of Antibody Variation (282)
Deoxyribonucleic acid repair in the yeast Saccharomyces cerevisiae. (276)
Novel bacteriophage lambda cloning vector. (274)
Detecting conserved regulatory elements with the model genome of the Japanese puffer fish, Fugu rubripes. (273)
Suffering in silence: the tolerance of DNA damage (266)
Two‐polymerase mechanisms dictate error‐free and error‐prone translesion DNA synthesis in mammals (263)
Characterization of a mutant strain of Saccharomyces cerevisiae with a deletion of the RAD27 gene, a structural homolog of the RAD2 nucleotide excision repair gene (260)
Mutants with altered muscle structure of Caenorhabditis elegans. (257)
Specific cleavage of model recombination and repair intermediates by the yeast Rad1-Rad10 DNA endonuclease. (254)
The genetics of behaviour. (252)
In vitro cloning of complex mixtures of DNA on microbeads: physical separation of differentially expressed cDNAs. (249)
Relationships between DNA repair and transcription. (247)
Nonsense mutants and polarity in the lac operon of Escherichia coli. (240)
A chemical genetic screen in Mycobacterium tuberculosis identifies carbon-source-dependent growth inhibitors devoid of in vivo efficacy (236)
Mutations causing transformation of sexual phenotype in the nematode Caenorhabditis elegans. (235)
Fidelity and Processivity of DNA Synthesis by DNA Polymerase κ, the Product of the Human DINB1 Gene* (228)
Impaired Genome Maintenance Suppresses the Growth Hormone–Insulin-Like Growth Factor 1 Axis in Mice with Cockayne Syndrome (223)
The theory of mutagenesis (219)
A phorbol ester/diacylglycerol-binding protein encoded by the unc-13 gene of Caenorhabditis elegans. (217)
Human Diseases Associated with Defective DNA Repair (216)
The many faces of DNA polymerases: strategies for mutagenesis and for mutational avoidance. (215)
RAD9-dependent G1 arrest defines a second checkpoint for damaged DNA in the cell cycle of Saccharomyces cerevisiae. (211)
Ochre mutants, a new class of suppressible nonsense mutants (205)
A mutant affecting the heavy chain of myosin in Caenorhabditis elegans. (203)
Ubiquitin-Binding Motifs in REV1 Protein Are Required for Its Role in the Tolerance of DNA Damage (203)
The 19S regulatory complex of the proteasome functions independently of proteolysis in nucleotide excision repair. (202)
REV1 protein interacts with PCNA: significance of the REV1 BRCT domain in vitro and in vivo. (197)
NONDISJUNCTION MUTANTS OF THE NEMATODE (197)
Structural components of bacteriophage (195)
The Saccharomyces cerevisiae Ku autoantigen homologue affects radiosensitivity only in the absence of homologous recombination. (193)
Late changes in spliceosomal introns define clades in vertebrate evolution. (192)
Sequences and consequences (191)
Interactions involving the human RNA polymerase II transcription/nucleotide excision repair complex TFIIH, the nucleotide excision repair protein XPG, and Cockayne syndrome group B (CSB) protein. (190)
Human and mouse homologs of Escherichia coli DinB (DNA polymerase IV), members of the UmuC/DinB superfamily. (187)
Duplicate genes for tyrosine transfer RNA in Escherichia coli. (183)
Evidence for at least six Hox clusters in the Japanese lamprey (Lethenteron japonicum) (181)
Nuclear protein-coding genes support lungfish and not the coelacanth as the closest living relatives of land vertebrates. (177)
Quantitative Analysis of Translesion DNA Synthesis across a Benzo[a]pyrene-Guanine Adduct in Mammalian Cells (177)
Molecular synapomorphies resolve evolutionary relationships of extant jawed vertebrates (177)
Intergenerational and striatal CAG repeat instability in Huntington's disease knock-in mice involve different DNA repair genes (176)
Yeast DNA repair and recombination proteins Rad1 and Rad1O constitute a single-stranded-DNA endonuclease (175)
DNA repair: from molecular mechanism to human disease. (173)
Heterozygosity for the mouse Apex gene results in phenotypes associated with oxidative stress. (173)
Nucleotide sequence of the gene encoding the hydrogenase from Desulfovibrio vulgaris (Hildenborough). (170)
CONSERVATION OF RIBOSOMES DURING BACTERIAL GROWTH. (168)
Mutagenesis of bacteriophage T4 by acridines. (164)
Protein structural domains in the Caenorhabditis elegans unc-54 myosin heavy chain gene are not separated by introns. (164)
A method for counting PCR template molecules with application to next-generation sequencing (164)
Extensive expansion of the claudin gene family in the teleost fish, Fugu rubripes. (163)
Correction of xeroderma pigmentosum complementation group D mutant cell phenotypes by chromosome and gene transfer: involvement of the human ERCC2 DNA repair gene. (162)
Massively parallel signature sequencing (MPSS) as a tool for in-depth quantitative gene expression profiling in all organisms. (161)
Reduced RNA polymerase II transcription in intact and permeabilized Cockayne syndrome group B cells. (160)
The End of the Beginning (160)
The Future of Psychiatric Research: Genomes and Neural Circuits (160)
Synthetic methods for the implementation of encoded combinatorial chemistry (158)
Rhizobium sp. Strain NGR234 Possesses a Remarkable Number of Secretion Systems (154)
Comparative analysis of the polycystic kidney disease 1 (PKD1) gene reveals an integral membrane glycoprotein with multiple evolutionary conserved domains. (154)
Transcription factor b (TFIIH) is required during nucleotide-excision repair in yeast (154)
Phosphotransferase sequence homology (153)
A Strong Suppressor Specific for UGA (153)
Identical short peptide sequences in unrelated proteins can have different conformations: a testing ground for theories of immune recognition. (151)
UGA: A Third Nonsense Triplet in the Genetic Code (151)
Mapping of suppressor loci in Escherichia coli. (149)
Molecular Mechanisms of Pyrimidine Dimer Excision in Saccharomyces cerevisiae: Incision of Ultraviolet-Irradiated Deoxyribonucleic Acid In Vivo (149)
The role of endogenous and exogenous DNA damage and mutagenesis. (148)
Y-family DNA polymerases in mammalian cells (147)
The Molecular Biology of Nucleotide Excision Repair of DNA: Recent Progress (146)
Small is beautiful: comparative genomics with the pufferfish (Fugu rubripes). (145)
Organization of the Fugu rubripes Hox clusters: evidence for continuing evolution of vertebrate Hox complexes (145)
More mutant tyrosine transfer ribonucleic acids. (144)
Origin and diversity of the SOX transcription factor gene family: genome-wide analysis in Fugu rubripes. (144)
Characterization of G1 checkpoint control in the yeast Saccharomyces cerevisiae following exposure to DNA-damaging agents. (144)
DNA polymerase κ deficiency does not affect somatic hypermutation in mice (142)
Unique insertion site of Tn7 in the E. coli chromosome (140)
Asilomar conference on recombinant DNA molecules. (140)
Deletion of the Saccharomyces cerevisiae gene RAD30 encoding an Escherichia coli DinB homolog confers UV radiation sensitivity and altered mutability (139)
MOLECULAR CONSEQUENCES OF THE AMBER MUTATION AND ITS SUPPRESSION. (136)
Integration of the Genetic Map and Genome Assembly of Fugu Facilitates Insights into Distinct Features of Genome Evolution in Teleosts and Mammals (135)
Defective thymine dimer excision by cell-free extracts of xeroderma pigmentosum cells. (133)
Encyclopedia of genetics (132)
Prolonged survival and decreased abnormal movements in transgenic model of Huntington disease, with administration of the transglutaminase inhibitor cystamine (131)
Lambda foo: a lambda phage vector for the expression of foreign proteins. (131)
Surface Display of Proteins on Bacteriophage λ Heads (130)
Comparative sequence analysis of the human and pufferfish Huntington's disease genes (130)
Models: The Third Dimension of Science (128)
A uniform genetic nomenclature for the nematode Caenorhabditis elegans (128)
Paramyosin gene (unc-15) of Caenorhabditis elegans. Molecular cloning, nucleotide sequence and models for thick filament structure. (126)
Deletion of XPC leads to lung tumors in mice and is associated with early events in human lung carcinogenesis. (126)
The conserved role of Krox-20 in directing Hox gene expression during vertebrate hindbrain segmentation. (123)
Error-Prone DNA Polymerases Novel Structures and the Benefits of Infidelity (123)
A pyrimidine dimer–DNA glycosylase activity associated with the v gene product of bacteriophage T4 (123)
Characterization of defective nucleotide excision repair in XPC mutant mice. (121)
Novel DNA Polymerases Offer Clues to the Molecular Basis of Mutagenesis (121)
Role of the Rad1 and Rad10 Proteins in Nucleotide Excision Repair and Recombination (*) (120)
Database of mouse strains carrying targeted mutations in genes affecting biological responses to DNA damage Version 7. (120)
DNA repair synthesis during base excision repair in vitro is catalyzed by DNA polymerase epsilon and is influenced by DNA polymerases alpha and delta in Saccharomyces cerevisiae. (120)
A mutant which reinitiates the polypeptide chain after chain termination. (118)
Dark Repair of Ultraviolet-Irradiated Deoxyribonucleic Acid by Bacteriophage T4: Purification and Characterization of a Dimer-Specific Phage-Induced Endonuclease (116)
Molecular cloning of the novel human G protein-coupled receptor (GPCR) gene mapped on chromosome 9. (113)
Ancient Noncoding Elements Conserved in the Human Genome (112)
Putative pheromone receptors related to the Ca2+-sensing receptor in Fugu. (110)
Amber suppressors: efficiency of chain propagation and suppressor specific amino acids. (110)
Purification and Characterization of polκ, a DNA Polymerase Encoded by the Human DINB1 Gene* (109)
Liquid-phase combinatorial synthesis. (109)
N-Glycosidase activity in extracts of Bacillus subtilis and its inhibition after infection with bacteriophage PBS2 (109)
DinB Upregulation Is the Sole Role of the SOS Response in Stress-Induced Mutagenesis in Escherichia coli (108)
Nucleotide excision repair of DNA by human cell extracts is suppressed in reconstituted nucleosomes. (106)
Human DNA Polymerase κ Bypasses and Extends beyond Thymine Glycols during Translesion Synthesis in Vitro, Preferentially Incorporating Correct Nucleotides* (105)
The 19S complex of the proteasome regulates nucleotide excision repair in yeast. (104)
A CHEMICAL BASIS FOR THE HOST-INDUCED MODIFICATION OF T-EVEN BACTERIOPHAGES. (104)
A yeast excision-repair gene is inducible by DNA damaging agents. (103)
Manitoba aboriginal kindred with original cerebro-oculo- facio-skeletal syndrome has a mutation in the Cockayne syndrome group B (CSB) gene. (102)
A new selective phage cloning vector, λ2001, with sites for XbaI, BamHI, HindIII, EcoRI, SstI and XhoI (101)
Evolution of the neuropeptide Y family: new genes by chromosome duplications in early vertebrates and in teleost fishes. (100)
UVB radiation-induced cancer predisposition in Cockayne syndrome group A (Csa) mutant mice. (100)
Molecular analysis of the unc-54 myosin heavy-chain gene of Caenorhabditis elegans (100)
Mutants affecting paramyosin in Caenorhabditis elegans. (98)
Mechanisms and Consequences of DNA Damage Processing (97)
Highly conserved syntenic blocks at the vertebrate Hox loci and conserved regulatory elements within and outside Hox gene clusters. (97)
Mutant tyrosine transfer ribonucleic acids. (97)
Transgenic rats reveal functional conservation of regulatory controls between the Fugu isotocin and rat oxytocin genes. (96)
The presence of nuclear and mitochondrial uracil-DNA glycosylase in extracts of human KB cells. (96)
Generation and analysis of 25 Mb of genomic DNA from the pufferfish Fugu rubripes by sequence scanning. (95)
Phase-Shift and Other Mutants in the First Part of the rII B Cistron of Bacteriophage T4 (95)
Identification of the structural gene for a myosin heavy-chain in Caenorhabditis elegans. (94)
Molecular cloning of two cannabinoid type 1-like receptor genes from the puffer fish Fugu rubripes. (93)
The yeast TFB1 and SSL1 genes, which encode subunits of transcription factor IIH, are required for nucleotide excision repair and RNA polymerase II transcription (92)
Duplication, degeneration and subfunctionalization of the nested synapsin-Timp genes in Fugu. (92)
Isolation, characterization and evolution of nine pufferfish (Fugu rubripes) actin genes. (92)
Nature's Gift to Science (Nobel Lecture) (92)
A suppressor mutation in the nematode acting on specific alleles of many genes (90)
Short Promoters in Viral Vectors Drive Selective Expression in Mammalian Inhibitory Neurons, but do not Restrict Activity to Specific Inhibitory Cell-Types (89)
ON THE IMPOSSIBILITY OF ALL OVERLAPPING TRIPLET CODES IN INFORMATION TRANSFER FROM NUCLEIC ACID TO PROTEINS. (89)
Partial suppression of an ochre mutation in Saccharomyces cerevisiae by multicopy plasmids containing a normal yeast tRNAGln gene. (89)
Cockayne syndrome – a primary defect in DNA repair, transcription, both or neither? (88)
Defective nucleotide excision repair in xpc mutant mice and its association with cancer predisposition. (88)
The DNA helicase and adenosine triphosphatase activities of yeast Rad3 protein are inhibited by DNA damage. A potential mechanism for damage-specific recognition. (87)
Molecular cloning of the pufferfish (Takifugu rubripes) Mx gene and functional characterization of its promoter (87)
A DNA repair gene required for the incision of damaged DNA is essential for viability in Saccharomyces cerevisiae. (86)
Characterization of the neurohypophysial hormone gene loci in elephant shark and the Japanese lamprey: origin of the vertebrate neurohypophysial hormone genes (86)
Genetic alterations in the tyrosine kinase transcriptome of human cancer cell lines. (86)
Stable and specific association between the yeast recombination and DNA repair proteins RAD1 and RAD10 in vitro. (84)
Elephant shark (Callorhinchus milii) provides insights into the evolution of Hox gene clusters in gnathostomes (83)
Fugu: a compact vertebrate reference genome (83)
Cloning and sequencing of the gene encoding cytochrome c3 from Desulfovibrio vulgaris (Hildenborough). (83)
3 Cellular Responses to DNA Damage in Yeast (83)
A brief history of the DNA repair field (83)
Aptamer selection by high-throughput sequencing and informatic analysis. (81)
DNA ligase I from Saccharomyces cerevisiae: physical and biochemical characterization of the CDC9 gene product. (80)
Description of the erythromycin-producing bacterium Arthrobacter sp. strain NRRL B-3381 as Aeromicrobium erythreum gen. nov., sp. nov. (80)
[On the regulation of DNA synthesis in bacteria: the hypothesis of the replicon]. (80)
Molecularizing Biology and Medicine: New Practices and Alliances 1910s - 1970s (79)
Canonical ordered cosmid library of the symbiotic plasmid of Rhizobium species NGR234. (79)
The RAD7, RAD16, and RAD23 genes of Saccharomyces cerevisiae: requirement for transcription-independent nucleotide excision repair in vitro and interactions between the gene products (79)
A speculation on the origin of protein synthesis (79)
Differential role of transcription-coupled repair in UVB-induced G2 arrest and apoptosis in mouse epidermis. (79)
Synergistic interactions between XPC and p53 mutations in double-mutant mice: neural tube abnormalities and accelerated UV radiation-induced skin cancer (79)
Cloning and functional expression of cDNAs encoding human and rat pancreatic polypeptide receptors. (79)
Genes For Tfb2, Tfb3, and Tfb4 Subunits of Yeast Transcription/Repair Factor IIH (77)
Ancient vertebrate conserved noncoding elements have been evolving rapidly in teleost fishes. (77)
Endonucleolytic cleavage of UV-irradiated DNA controlled by the V+ gene in phage T4. (77)
den V gene of bacteriophage T4 codes for both pyrimidine dimer-DNA glycosylase and apyrimidinic endonuclease activities (77)
Conservation of synteny between the genome of the pufferfish (Fugu rubripes) and the region on human chromosome 14 (14q24.3) associated with familial Alzheimer disease (AD3 locus) (76)
Yeast nucleotide excision repair proteins Rad2 and Rad4 interact with RNA polymerase II basal transcription factor b (TFIIH). (76)
Nucleotide-excision repair of DNA in cell-free extracts of the yeast Saccharomyces cerevisiae. (76)
The Caenorhabditis elegans unc-13 gene product is a phospholipid-dependent high-affinity phorbol ester receptor. (75)
Paramyosin of Caenorhabditis elegans. (75)
Xeroderma pigmentosum, Cockayne's syndrome, helicases, and DNA repair: What's the relationship? (74)
Ultraviolet B radiation-induced skin cancer in mice defective in the Xpc, Trp53, and Apex (HAP1) genes: genotype-specific effects on cancer predisposition and pathology of tumors. (74)
The kinetics of thymine dimer excision in ultraviolet-irradiated human cells. (74)
Of worms and programmes: Caenorhabditis elegans and the study of development (74)
Cloning of the gene encoding the hydrogenase from Desulfovibrio vulgaris (Hildenborough) and determination of the NH2-terminal sequence. (74)
Out of the shadows and into the light: the emergence of DNA repair. (73)
Reduced RNA polymerase II transcription in extracts of cockayne syndrome and xeroderma pigmentosum/Cockayne syndrome cells. (73)
Factors that determine connectivity in the nervous system of Caenorhabditis elegans. (73)
Semi-conservative deoxyribonucleic acid synthesis in unirradiated and ultraviolet-irradiated xeroderma pigmentosum and normal human skin fibroblasts. (72)
Identification of an evolutionarily conserved 110 base-pair cis-acting regulatory sequence that governs Wnt-1 expression in the murine neural plate. (72)
DNA Banks for Endangered Animal Species (72)
Mutational inactivation of the xeroderma pigmentosum group C gene confers predisposition to 2-acetylaminofluorene-induced liver and lung cancer and to spontaneous testicular cancer in Trp53-/- mice. (72)
Fugu and human sequence comparison identifies novel human genes and conserved non-coding sequences. (71)
Partial purification and characterization of a uracil DNA N-glycosidase from Bacillus subtilis. (71)
Molecular rotors as conditionally fluorescent labels for rapid detection of biomolecular interactions. (71)
Early vertebrate chromosome duplications and the evolution of the neuropeptide Y receptor gene regions (71)
Constitutive and regulated expression of the mouse Dinb (Polkappa) gene encoding DNA polymerase kappa. (70)
Inhibitor of uracil-DNA glycosylase induced by bacteriophage PBS2. Purification and preliminary characterization. (70)
Yeast autonomously replicating sequence binding factor is involved in nucleotide excision repair. (70)
Genetic Basis of Tetrodotoxin Resistance in Pufferfishes (69)
Database of mouse strains carrying targeted mutations in genes affecting cellular responses to DNA damage: version 3. (69)
Normal yeast tRNA(CAGGln) can suppress amber codons and is encoded by an essential gene. (69)
Deoxyribonucleic acid excision repair in chromatin after ultraviolet irradiation of human fibroblasts in culture. (68)
Database of mouse strains carrying targeted mutations in genes affecting biological responses to DNA damage. Version 5. (68)
Turing centenary: Life's code script (68)
Chromosome rearrangements in Caenorhabditis elegans. (68)
Expression of the mosquitocidal toxins of Bacillus sphaericus and Bacillus thuringiensis subsp. israelensis by recombinant Caulobacter crescentus, a vehicle for biological control of aquatic insect larvae (67)
Into the blue: gene duplication and loss underlie color vision adaptations in a deep-sea chimaera, the elephant shark Callorhinchus milii. (67)
Mouse models for xeroderma pigmentosum group A and group C show divergent cancer phenotypes. (67)
Recursive deconvolution of combinatorial chemical libraries. (66)
Erythropoietin gene from a teleost fish, Fugu rubripes. (66)
Molecular cloning and characterization of Saccharomyces cerevisiae RAD28, the yeast homolog of the human Cockayne syndrome A (CSA) gene (65)
Requirements for the Interaction of Mouse Polκ with Ubiquitin and Its Biological Significance* (65)
RAD3 gene of Saccharomyces cerevisiae: nucleotide sequence of wild-type and mutant alleles, transcript mapping, and aspects of gene regulation. (65)
DNA-Encoded Compound Libraries as Open Source: A Powerful Pathway to New Drugs. (64)
Designs for Life: Molecular Biology after World War II (63)
The yeast Rad7/Rad16/Abf1 complex generates superhelical torsion in DNA that is required for nucleotide excision repair. (61)
Age-dependent spontaneous mutagenesis in Xpc mice defective in nucleotide excision repair (61)
Conserved regulation of the lymphocyte-specific expression of lck in the Fugu and mammals (60)
Hox gene clusters in the Indonesian coelacanth, Latimeria menadoensis (59)
Organization of host‐inducible transcripts on the symbiotic plasmid of Rhizobium sp. NGR234 (58)
Polk mutant mice have a spontaneous mutator phenotype. (57)
Analysis of the dopamine receptor family in the compact genome of the puffer fish Fugu rubripes. (57)
Indirect suppression in Caenorhabditis elegans. (57)
Genomic structure and sequence of the pufferfish (Fugu rubripes) growth hormone-encoding gene: a comparative analysis of teleost growth hormone genes. (57)
Oxidative stress alters base excision repair pathway and increases apoptotic response in apurinic/apyrimidinic endonuclease 1/redox factor-1 haploinsufficient mice. (56)
DNA polymerase κ-dependent DNA synthesis at stalled replication forks is important for CHK1 activation (56)
DNA Excision Repair Pathways (55)
Endonuclease II of E. coli. I. Isolation and purification. (55)
Neuropeptide Y-family peptides and receptors in the elephant shark, Callorhinchus milii confirm gene duplications before the gnathostome radiation. (55)
Yeast DNA recombination and repair proteins Rad 1 and Radio constitute a complex in vivo mediated by localized hydrophobic domains (55)
Investigation of loss and gain of introns in the compact genomes of pufferfishes (Fugu and Tetraodon). (55)
Database of mouse strains carrying targeted mutations in genes affecting biological responses to DNA damage (Version 6). (54)
Photoreactivation of thymine dimers in UV-irradiated human cells: unique dependence on culture conditions. (54)
Genetic interaction between HAP1/REF-1 and p53 (53)
Inhibition of Rad3 DNA helicase activity by DNA adducts and abasic sites: implications for the role of a DNA helicase in damage-specific incision of DNA. (52)
Studies on the substrate specificity of the T 4 excision repair endonuclease. (52)
The Yeast RAD7 and RAD16 Genes Are Required for Postincision Events during Nucleotide Excision Repair (52)
The Saccharomyces cerevisiae MEC1 gene, which encodes a homolog of the human ATM gene product, is required for G1 arrest following radiation treatment (51)
Subtraction hybridisation and shot-gun sequencing: a new approach to identify symbiotic loci. (51)
Genomic structure and sequence of the Fugu rubripes glucose-6-phosphate dehydrogenase gene (G6PD). (51)
A selection for myosin heavy chain mutants in the nematode Caenorhabditis elegans. (51)
Correcting the Blueprint of Life: An Historical Account of the Discovery of DNA Repair Mechanisms (51)
Electron Microscopic Studies on Substrate Specificity of T4 Excision Repair Endonuclease (51)
Measurement of thymine dimers in DNA by thin-layer chromatography. II. The use of one-dimensional systems. (50)
A compact cartilaginous fish model genome (50)
Regulation of the RAD2 gene of Saccharomyces cervisiae (50)
Specificity of the bacteriophage PBS2 induced inhibitor of uracil-DNA glycosylase. (49)
The DNA damage signal for Mdm2 regulation, Trp53 induction, and sunburn cell formation in vivo originates from actively transcribed genes. (48)
The fifth neurohypophysial hormone receptor is structurally related to the V2-type receptor but functionally similar to V1-type receptors. (48)
Laboratory science versus country-house experiments. The controversy between Julius Sachs and Charles Darwin (48)
Sequence and organization of coelacanth neurohypophysial hormone genes: Evolutionary history of the vertebrate neurohypophysial hormone gene locus (48)
Endonuclease II of Escherichia coli. II. Enzyme properties and studies on the degradation of alkylated and native deoxyribonucleic acid. (47)
Analysis of the essential and excision repair functions of the RAD3 gene of Saccharomyces cerevisiae by mutagenesis. (47)
Distribution of Proflavin-Induced Mutations in the Genetic Fine Structure (46)
Measurement of thymine dimers in DNA by thin-layer chromatography. (46)
STAT4 is a target of the hematopoietic zinc‐finger transcription factor Ikaros in T cells (46)
Conserved linkage between the puffer fish (Fugu rubripes) and human genes for platelet-derived growth factor receptor and macrophage colony-stimulating factor receptor. (46)
Studies on gene transfer and reversion to UV resistance in xeroderma pigmentosum cells (46)
Molecular cloning of 5-hydroxytryptamine (5-HT) type 1 receptor genes from the Japanese puffer fish, Fugu rubripes. (45)
Comparative analysis of in vivo interactions between Rev1 protein and other Y-family DNA polymerases in animals and yeasts. (45)
NOBEL LECTURE: Nature's Gift to Science (45)
Apurinic/Apyrimidinic Endonuclease (APE/REF-1) Haploinsufficient Mice Display Tissue-specific Differences in DNA Polymerase β-Dependent Base Excision Repair* (45)
Sequencing of Pax6 Loci from the Elephant Shark Reveals a Family of Pax6 Genes in Vertebrate Genomes, Forged by Ancient Duplications and Divergences (44)
Gene transduction in skin cells: preventing cancer in xeroderma pigmentosum mice. (44)
Cloning and sequencing of complement component C9 and its linkage to DOC-2 in the pufferfish Fugu rubripes. (44)
Cloning and characterization of RAD17, a gene controlling cell cycle responses to DNA damage in Saccharomyces cerevisiae. (44)
Purification and characterization of Rad3 ATPase/DNA helicase from Saccharomyces cerevisiae. (43)
Characterization of the recombinase activating gene-1 and 2 locus in the Japanese pufferfish, Fugu rubripes. (43)
Nucleotide excision repair in the yeast Saccharomyces cerevisiae: its relationship to specialized mitotic recombination and RNA polymerase II basal transcription. (43)
Identification of an ochre-suppressing anticodon. (43)
Out of print (43)
Enzymatic degradation of uracil-containing DNA. II. Evidence for N-glycosidase and nuclease activities in unfractionated extracts of Bacillus subtilis (43)
Analysis of 148 kb of genomic DNA around the wnt1 locus of Fugu rubripes. (43)
Saccharomyces cerevisiae RAD2 gene: isolation, subcloning, and partial characterization. (43)
Studies on amber suppressor tRNA. (43)
Effects of multiple yeast rad3 mutant alleles on UV sensitivity, mutability, and mitotic recombination (42)
Mutations That Affect Dimer Formation and Helicase Activity of the Hepatitis C Virus Helicase (42)
Molecular cloning of eucaryotic genes required for excision repair of UV-irradiated DNA: isolation and partial characterization of the RAD3 gene of Saccharomyces cerevisiae (42)
The ultraviolet endonuclease of bacteriophage T4. Further characterization. (42)
Genes and development: molecular and logical themes. (42)
Theoretical biology in the third millennium. (42)
Mice defective in the mismatch repair gene Msh2 show increased predisposition to UVB radiation-induced skin cancer. (42)
Database of mouse strains carrying targeted mutations in genes affecting cellular responses to DNA damage. Version 4. (41)
In the Beginning Was the Worm … (41)
Phasmids: hybrids between ColE1 plasmids and E. coli bacteriophage lambda. (41)
Environmental and molecular mutagenesis: Editorial note (40)
Identification and analysis of additional copies of the platelet-derived growth factor receptor and colony stimulating factor 1 receptor genes in fugu. (40)
An internal deletion mutant of a myosin heavy chain in Caenorhabditis elegans. (40)
Elephant shark sequence reveals unique insights into the evolutionary history of vertebrate genes: A comparative analysis of the protocadherin cluster (39)
Surface display of proteins on bacteriophage lambda heads. (39)
New bacteriophage lambda vectors with positive selection for cloned inserts. (39)
Structural and mutational analysis of the xeroderma pigmentosum group D (XPD) gene. (39)
Defective recovery of semi-conservative DNA synthesis in xeroderma pigmentosum cells following split-dose ultraviolet irradiation. (39)
Eukaryotic DNA repair: Glimpses through the yeast Saccharomyces cerevisiae (39)
Methods for sorting polynucleotides using oligonucleotide tags (39)
Yeast RNA Polymerase II Transcription In Vitro Is Inhibited in the Presence of Nucleotide Excision Repair: Complementation of Inhibition by Holo-TFIIH and Requirement for RAD26 (38)
An erythromycin-resistance gene from an erythromycin-producing strain of Arthrobacter sp. (38)
Database of mouse strains carrying targeted mutations in genes affecting cellular responses to DNA damage (38)
Large number of ultraconserved elements were already present in the jawed vertebrate ancestor. (37)
Yeast genes involved in DNA‐repair processes: new looks on old faces (37)
Involvement of Vertebrate Polκ in Translesion DNA Synthesis across DNA Monoalkylation Damage* (37)
Yeast RAD3 protein binds directly to both SSL2 and SSL1 proteins: implications for the structure and function of transcription/repair factor b. (37)
Something fishy in the rat brain: molecular genetics of the hypothalamo‐neurohypophysial system (36)
A functional role for some Fugu introns larger than the typical short ones: the example of the gene coding for ribosomal protein S7 and snoRNA U17. (36)
Physical mapping and complete nucleotide sequence of the denV gene of bacteriophage T4 (36)
DNA Repair Enzymes in Mammalian Cells (35)
RAD4 gene of Saccharomyces cerevisiae: molecular cloning and partial characterization of a gene that is inactivated in Escherichia coli. (35)
A survey of ancient conserved non-coding elements in the PAX6 locus reveals a landscape of interdigitated cis-regulatory archipelagos. (35)
The RAD2 gene of Saccharomyces cerevisiae: nucleotide sequence and transcript mapping. (35)
Molecular Cloning and Genomic Structure of a Gene Encoding Interferon Regulatory Factor in the Pufferfish (Fugu rubripes) (35)
Changes in PDE4D isoforms in the hippocampus of a patient with advanced Alzheimer disease. (34)
The DNA helicase activities of Rad3 protein of Saccharomyces cerevisiae and helicase II of Escherichia coli are differentially inhibited by covalent and noncovalent DNA modifications. (34)
Following Molecules: Hemoglobin Between the Clinic and the Laboratory (34)
Functional complementation of ataxia-telangiectasia group D (AT-D) cells by microcell-mediated chromosome transfer and mapping of the AT-D locus to the region 11q22-23. (34)
DNA REPAIR OF ULTRAVIOLET‐IRRADIATED BACTERIOPHAGE T4 (34)
TFCONES: A database of vertebrate transcription factor-encoding genes and their associated conserved noncoding elements (34)
Erratum: Trading places: How do DNA polymerases switch during translesion DNA synthesis? (Molecular Cell (May 27, 2005) 18 (499-505) PII: S1097-2765(05)01276-1 and DOI: 10.1016/j.molcel.2005.03.032) (33)
Nuclear targeting sequences. (33)
RNA, ribosomes, and protein synthesis. (33)
Sequences, conformation, information: Biochemists and molecular biologists in the 1950s (33)
General Nature of the Genetic Code for Proteins (33)
Microcell-mediated transfer of a single human chromosome complements xeroderma pigmentosum group A fibroblasts. (33)
Identification and characterization of novel mouse PDE4D isoforms: molecular cloning, subcellular distribution and detection of isoform-specific intracellular localization signals. (33)
Excision of thymine dimers by proteolytic and amber fragments of E. coli DNA polymerase I. (33)
FANCD2 and REV1 cooperate in the protection of nascent DNA strands in response to replication stress (32)
Cancer predisposition in mutant mice defective in multiple genetic pathways: uncovering important genetic interactions. (32)
Single-Molecule Detection by Laser-Induced Fluorescence Technique with a Position-Sensitive Photon-Counting Apparatus (32)
Genomic structure and nucleotide sequence of the p55 gene of the puffer fish Fugu rubripes. (32)
Transcription and nucleotide excision repair--reflections, considerations and recent biochemical insights. (31)
Biological computation. (31)
Correlation between genetic and translational maps of gene 23 in bacteriophage T4. (31)
Conservation of all three p53 family members and Mdm2 and Mdm4 in the cartilaginous fish (31)
Human chromosome 15 confers partial complementation of phenotypes to xeroderma pigmentosum group F cells. (31)
Correction: Impaired Genome Maintenance Suppresses the Growth Hormone–Insulin-Like Growth Factor 1 Axis in Mice with Cockayne Syndrome (31)
The inactivation of the XP-C gene does not affect somatic hypermutation or class switch recombination of immunoglobulin genes. (31)
Excision of thymine dimers from specifically incised DNA by extracts of xeroderma pigmentosum cells (31)
Deoxyribonucleic Acid Repair in Bacteriophage T4: Observations on the Roles of the x and v Genes and of Host Factors (30)
Molecular aspects of DNA repair. (30)
On the interaction of adsorption cofactors with bacteriophages T2 and T4. (30)
The p53-Mdm2 interaction and the E3 ligase activity of Mdm2/Mdm4 are conserved from lampreys to humans. (30)
Human diseases with genetically altered DNA repair processes. (30)
A novel calmodulin-like gene from the nematode Caenorhabditis elegans. (30)
Elevated mutation rates in the germline of Polκ mutant male mice (29)
Fugu genome does not contain mitochondrial pseudogenes. (29)
Cancer predisposition in mutant mice defective in the XPC DNA repair gene. (29)
Influence of DNA repair deficiencies on the UV sensitivity of yeast cells in different cell cycle stages. (29)
Novel vertebrate genes and putative regulatory elements identified at kidney disease and NR2E1/fierce loci. (29)
DNA repair and transcription. (28)
Improvements in the Epstein-Barr-based shuttle vector system for direct cloning in human tissue culture cells (28)
A new DNA-dependent ATPase which stimulates yeast DNA polymerase I and has DNA-unwinding activity. (28)
ABF1-binding Sites Promote Efficient Global Genome Nucleotide Excision Repair* (28)
What lies ahead? (28)
The tuberin (TSC2), autosomal dominant polycystic kidney disease (PKD1), and somatostatin type V receptor (SSTR5) genes form a synteny group in the Fugu genome. (28)
Absence of a pyrimidine dimer repair mechanism for mitochondrial DNA in mouse and human cells. (28)
Molecular mechanisms of pyrimidine dimer excision in Saccharomyces cerevisiae: excision of dimers in cell extracts (28)
Physiological levels of normal tRNA(CAGGln) can effect partial suppression of amber mutations in the yeast Saccharomyces cerevisiae. (28)
Structure and organization of the isotocin and vasotocin genes from teleosts. (27)
Molecular cloning and characterization of the yeast RAD10 gene and expression of RAD10 protein in E. coli. (27)
Cloning and expression of the reverse transcriptase component of pufferfish (Fugu rubripes) telomerase. (27)
Why do cells have multiple error‐prone DNA polymerases? (27)
The Detection and Measurement of Base and Nucleotide Excision Repair in Cell-Free Extracts of the Yeast Saccharomyces cerevisiae (27)
Genotype-specific Trp53 mutational analysis in ultraviolet B radiation-induced skin cancers in Xpc and Xpc Trp53 mutant mice. (27)
Graphical method and discipline: Self-recording instruments in nineteenth-century physiology (27)
Variants of mouse DNA polymerase κ reveal a mechanism of efficient and accurate translesion synthesis past a benzo[a]pyrene dG adduct (27)
Cloning the Drosophila homolog of the xeroderma pigmentosum complementation group C gene reveals homology between the predicted human and Drosophila polypeptides and that encoded by the yeast RAD4 gene. (27)
Molecular Mechanism of Base Excision Repair of Uracil-containing DNA in Yeast Cell-free Extracts* (27)
Phase shifting of amber and ochre mutants (26)
Mouse DNA polymerase kappa has a functional role in the repair of DNA strand breaks. (26)
Short-range linkage relationships, genomic organisation and sequence comparisons of a cluster of five HSP70 genes in Fugu rubripes (26)
Fabulous Science: Fact and Fiction in the History of Scientific Discovery (26)
Parathyroid hormone gene family in a cartilaginous fish, the elephant shark (Callorhinchus milii) (26)
Genetic control and phenotypic mixing of the adsorption cofactor requirement in bacteriophages T2 and T4. (26)
Pufferfish and Zebrafish Have Five Distinct NPY Receptor Subtypes, but Have Lost Appetite Receptors Y1 and Y5 (26)
Regions of human chromosome 2 (2q32-q35) and mouse chromosome 1 show synteny with the pufferfish genome (Fugu rubripes). (26)
Subunit Interactions in Yeast Transcription/Repair Factor TFIIH (26)
The Revolution in the Life Sciences (25)
Purification of Rad1 protein from Saccharomyces cerevisiae and further characterization of the Rad1/Rad10 endonuclease complex. (25)
New directions in molecular biology (25)
The eureka enzyme: the discovery of DNA polymerase (25)
Bacteriophage growth in protoplasts of Bacillus megaterium. (25)
Giant‐cell carcinoma of the lung: A dedifferentiated adenocarcinoma (25)
Use of high-performance liquid chromatography to quantitate thymine-containing pyrimidine dimers in DNA. (25)
A history of the DNA repair and mutagenesis field: The discovery of base excision repair. (25)
The genome of the largest bony fish, ocean sunfish (Mola mola), provides insights into its fast growth rate (25)
Ray‐Fin Fish Tetraploidization Gave Rise to Pufferfish Duplicates of NPY and PYY, but Zebrafish NPY Duplicate Was Lost (25)
Neurone‐Specific Expression and Regulation of the Pufferfish Isotocin and Vasotocin Genes in Transgenic Mice (25)
Evolution and Functional Characterisation of Melanopsins in a Deep-Sea Chimaera (Elephant Shark, Callorhinchus milii) (25)
The Impact of Society on Science (24)
Molecular cloning and nucleotide sequence analysis of the Saccharomyces cerevisiae RAD1 gene. (24)
Affinity Purification and Partial Characterization of a Yeast Multiprotein Complex for Nucleotide Excision Repair Using Histidine-tagged Rad14 Protein* (24)
The chromatic nuclear membrane. (24)
Site-specific properties of Tn7 transposition into the E. coli Chromosome (24)
Identification of Functional Domains within the RAD1·RAD10 Repair and Recombination Endonuclease of Saccharomyces cerevisiae* (24)
Mice and the Reactor: The “Genetics Experiment” in 1950s Britain (24)
A yeast whole cell extract supports nucleotide excision repair and RNA polymerase II transcription in vitro. (24)
Mismatch repair protein MSH2 regulates translesion DNA synthesis following exposure of cells to UV radiation (24)
Purification and characterization of pol kappa, a DNA polymerase encoded by the human DINB1 gene. (24)
Clustering cDNA sequences (23)
Interview with Sydney Brenner (23)
Repair of nitrous acid damage to DNA in Escherichia coli. (23)
DNA fingerprinting by sampled sequencing. (23)
Induction of mutations in the deoxyribonucleic acid of phage T2 synthesized in the presence of chloramphenicol. (23)
Characterization of the Runx Gene Family in a Jawless Vertebrate, the Japanese Lamprey (Lethenteron japonicum) (23)
A yeast DNA repair gene partially complements defective excision repair in mammalian cells. (23)
Letter: Evidence for clustering of pyrimidine dimers on opposite strands of U.V.-irradiated bacteriophage DNA. (22)
The repair of DNA damage: recent developments and new insights. (22)
Recovery of RNA polymerase II synthesis following DNA damage in mutants of Saccharomyces cerevisiae defective in nucleotide excision repair. (22)
Purification and properties of a pyrimidine dimer-specific endonuclease from E. coli infected with bacteriophage T4. (21)
Reversible monoubiquitination of PCNA: A novel slant on regulating translesion DNA synthesis. (21)
Identification of MMS19 domains with distinct functions in NER and transcription. (21)
Excision of Thymine Dimers In Vitro by Extracts of Bacteriophage-Infected Escherichia coli (21)
Inducible system in human hepatoma cell lines for hepatitis C virus production. (21)
Interview with Sydney Brenner by Soraya de Chadarevian. (21)
The tools of the discipline: Biochemists and molecular biologists (21)
In the groove (21)
How are specialized (low-fidelity) eukaryotic polymerases selected and switched with high-fidelity polymerases during translesion DNA synthesis? (20)
The regulation of retina specific expression of rhodopsin gene in vertebrates. (20)
Cloning the human and mouse MMS19 genes and functional complementation of a yeast mms19 deletion mutant. (20)
Excision repair of DNA in nuclear extracts from the yeast Saccharomyces cerevisiae. (20)
The human genome: the nature of the enterprise. (20)
Rodent complementation group 8 (ERCC8) corresponds to Cockayne syndrome complementation group A. (20)
Mutations in the Trp53 gene of UV-irradiated Xpc mutant mice suggest a novel Xpc-dependent DNA repair process. (20)
Nucleotide excision repair of DNA in eukaryotes: comparisons between human cells and yeast. (20)
Microstudies versus big picture accounts (20)
Molecular mechanism of pyrimidine dimer excision in Saccharomyces cerevisiae. I. Studies with intact cells and cell-free systems. (20)
Nocardia elegans sp. nov., a member of the Nocardia vaccinii clade isolated from sputum. (19)
Nucleotide excision repair of DNA: The very early history. (19)
BASE EXCISION REPAIR OF DNA (19)
Elevated mutation rates in the germline of Polkappa mutant male mice. (19)
Two distinct DNA ligase activities in mitotic extracts of the yeast Saccharomyces cerevisiae. (19)
New insights into the combined Cockayne/xeroderma pigmentosum complex: human XPG protein can function in transcription factor stability. (19)
DNA repair, mutagenesis, and other responses to DNA damage : a subject collection from Cold Spring Harbor perspectives in biology (19)
Recent developments in the enzymology of excision repair of DNA. (18)
Life sentences: Ontology recapitulates philology (18)
Overexpression of the RAD2 gene of S. cerevisiae: Identification and preliminary characterization of Rad2 protein (18)
THE AMBER MUTATION. (18)
Enzymatic degradation of uracil-containing deoxyribonucleic acid. V. Survival of Escherichia coli and coliphages treated with sodium bisulfite (18)
A novel XPC pathogenic variant detected in archival material from a patient diagnosed with Xeroderma Pigmentosum: a case report and review of the genetic variants reported in XPC. (18)
The N-degron protein degradation strategy for investigating the function of essential genes: requirement for replication protein A and proliferating cell nuclear antigen proteins for nucleotide excision repair in yeast extracts. (18)
The combined effects of xeroderma pigmentosum C deficiency and mutagens on mutation rates in the mouse germ line. (18)
Enzymes involved in thymine dimer excision in bacteriophage T4-infected Escherichia coli. (17)
Genetic and chemical studies on the head protein of bacteriophages T2 and T4. (17)
The effects of ribonuclease and deoxyribonuclease on bacteriophage formation in protoplasts of Bacillus megaterium. (17)
Action of bacteriophage T4 ultraviolet endonuclease on duplex DNA containing one ultraviolet-irradiated strand. (17)
New bacteriophage lambda vectors with positive selection for cloned inserts. (17)
Endonuclease II of E. coli. (17)
Tetraodon genome analysis provides further evidence for whole-genome duplication in the ray-finned fish lineage. (17)
The conundrum of xeroderma pigmentosum--a rare disease with frequent complexities. (17)
Sydney Brenner (17)
Signal exchange mediates host-specific nodulation of tropical legumes by the broad host-range Rhizobium species NGR234 (17)
Life sentences: Detective Rummage investigates (17)
Faculty Opinions recommendation of MSH2-MSH6 stimulates DNA polymerase eta, suggesting a role for A:T mutations in antibody genes. (17)
Sillycon valley fever (17)
Theories of gene regulation. (16)
Molecular biology in postwar Europe: towards a 'glocal' picture (16)
Targeted detection of in vivo endogenous DNA base damage reveals preferential base excision repair in the transcribed strand (16)
Sensitivity of a S. cerevisiae RAD27 deletion mutant to DNA-damaging agents and in vivo complementation by the human FEN-1 gene. (16)
The discovery that xeroderma pigmentosum (XP) results from defective nucleotide excision repair. (16)
A novel p53 mutational hotspot in skin tumors from UV-irradiated Xpc mutant mice alters transactivation functions (16)
Characterization of a complex chromosomal rearrangement maps the locus for In vitro complementation of xeroderma pigmentosum group D to human chromosome band 19q 13 (16)
A history of the DNA repair and mutagenesis field: I. The discovery of enzymatic photoreactivation. (16)
One armed PCR (OA-PCR): amplification of genomic DNA from a single primer domain. (16)
Uneven evolutionary rates of bradykinin B1 and B2 receptors in vertebrate lineages. (16)
Cysteinyl‐tRNA synthetase is a direct descendant of the first aminoacyl‐tRNA synthetase (16)
Studies in History and Philosophy of Biological and Biomedical Sciences (16)
Mutant tyrosine transfer ribonucleic acids (16)
Mapping the worm's genome: tools, networks, patronage (15)
Zonal variations in the juxtaglomerular granules in mice of different ages. (15)
The Drosophila ortholog of the human XPG gene. (15)
Construction of plasmid vectors that facilitate subcloning and recovery of yeast and Escherichia coli DNA fragments. (15)
Rad10 exhibits lesion-dependent genetic requirements for recruitment to DNA double-strand breaks in Saccharomyces cerevisiae (15)
Genomics. The end of the beginning. (15)
Isolation and partial characterization of virus-transformed cell lines representing the A, G and variant complementation groups of xeroderma pigmentosum. (14)
Evidence that the Rad1 and Rad10 proteins of Saccharomyces cerevisiae participate as a complex in nucleotide excision repair of UV radiation damage (14)
Human DNA polymerase kappa: a novel DNA polymerase of unknown biological function encoded by the DINB1 gene. (14)
Hybrid T4 r II B cistrons created by genetic duplications. (14)
INCREASED LEVELS OF UNSCHEDULED DNA SYNTHESIS IN UV‐IRRADIATED HUMAN FIBROBLASTS PRETREATED WITH SODIUM BUTYRATE (14)
Chromosome Photography and the Human Karyotype (14)
Understanding the Human Brain (14)
The TFB4 Subunit of Yeast TFIIH Is Required for Both Nucleotide Excision Repair and RNA Polymerase II Transcription* (14)
The making of an entrepreneurial science: biotechnology in Britain, 1975-1995. (14)
Xeroderma pigmentosum: recent studies on the DNA repair defects. (14)
Non-histone chromosomal proteins of chemically transformed neoplastic cells in tissue culture. (14)
A DEMONSTRATION OF SEVERAL DEOXYRIBONUCLEASE ACTIVITIES IN MAMMALIAN CELL MITOCHONDRIA (14)
Myosin heavy chain gene amplification as a suppressor mutation in Caenorhabditis elegans (14)
Progress in Nucleic Acid Research (14)
Designs for life (14)
Endonuclease II of Escherichia coli. (13)
SnapShot: Nucleotide Excision Repair (13)
Multiple thymine dimer excising nuclease activities in extracts of human KB cells. (13)
THE DISTRIBUTION OF THE JUXTAGLOMERULAR GRANULES AND THE MACULA DENSA IN THE RENAL CORTEX OF THE MOUSE. (13)
An enzyme activity from Escherichia coli that attacks single-stranded deoxyribopolymers and single-stranded deoxyribonucleic acid containing apyrimidinic sites. (13)
Fungitoxic effects of nonprotein imino acids on growth of saprophytic fungi isolated from the leaf surface of Calliandra haematocephala (13)
Demonstration of pyrimidine dimer-DNA glycosylase activity in vivo: bacteriophage T4-infected Escherichia coli as a model system (13)
Transformation of Arthrobacter and studies on the transcription of the Arthrobacter ermA gene in Streptomyces lividans and Escherichia coli. (13)
Nonsense codons. (13)
Detoxification of olefinic epoxides and nucleotide excision repair of epoxide-mediated DNA damage: Insights from animal models examining human sensitivity to 1,3-butadiene. (13)
Conserved synteny between the Fugu and human PTEN locus and the evolutionary conservation of vertebrate PTEN function (13)
Identity of N2 and Ochre nonsense mutants (13)
Isolation and characterisation of the retinoic acid receptor-alpha gene in the Japanese pufferfish, F. rubripes. (12)
Interaction between cAMP-dependent protein kinase catalytic subunit and peptide inhibitors analyzed with lambda repressor fusions. (12)
Database of mouse strains carrying targeted mutations in genes affecting cellular responses to DNA damage. Version 2. (12)
Portrait of a Discovery (12)
Increased dietary cholesterol promotes enhanced mutagenesis in DNA polymerase kappa-deficient mice. (12)
Fugu intron oversize reveals the presence of U15 snoRNA coding sequences in some introns of the ribosomal protein S3 gene. (12)
Mutational inactivation of the Saccharomyces cerevisiae RAD4 gene in Escherichia coli (12)
Characterization of the RAD10 gene of Saccharomyces cerevisiae and purification of Rad10 protein. (12)
A mutation in a Saccharomyces cerevisiae gene (RAD3) required for nucleotide excision repair and transcription increases the efficiency of mismatch correction. (12)
Nucleotide sequence of the wild-type RAD4 gene of Saccharomyces cerevisiae and characterization of mutant rad4 alleles (12)
The worm's turn (12)
G protein alpha subunit multigene family in the Japanese puffer fish Fugu rubripes: PCR from a compact vertebrate genome. (12)
Biological responses to DNA damage: a perspective in the new millennium. (12)
DNA repair: looking back and peering forward. (12)
3,4‐Epoxy‐1‐butene, a reactive metabolite of 1,3‐butadiene, induces somatic mutations in Xpc‐null mice (12)
Molecular cloning of EDG‐3 and N‐Shc genes from the puffer fish, Fugu rubripes, and conservation of synteny with the human genome (11)
Hunters and gatherers. (11)
Sydney Brenner: A Biography (11)
Lampreys, the jawless vertebrates, contain only two ParaHox gene clusters (11)
Static electric fields interfere in the viability of cells exposed to ionising radiation (11)
Compact intergenic regions of the pufferfish genome facilitate isolation of gene promoters: characterization of Fugu 3′‐phosphoadenosine 5′‐phosphosulfate synthase 2 (fPapss2) gene promoter function in transgenic Xenopus (11)
Sequencing and Analysis of Full-Length cDNAs, 5′-ESTs and 3′-ESTs from a Cartilaginous Fish, the Elephant Shark (Callorhinchus milii) (11)
Changes in the periplasmic linker and in the expression level affect the activity of ToxR and λ‐ToxR fusion proteins in Escherichia coli (11)
Spectrum of 32P-induced mutants of Caenorhabditis elegans. (11)
Characterization of approximately 50 kb of the immunoglobulin VH locus of the Japanese pufferfish, Fugu rubripes (11)
NATURE’S GIFT TO SCIENCE (11)
Lobar pilocytic astrocytomas of the cerebral hemispheres: II. Pathobiology--morphogenesis of the eosinophilic granular bodies. (11)
Confirmation of homozygosity for a single nucleotide substitution mutation in a Cockayne syndrome patient using monoallelic mutation analysis in somatic cell hybrids (11)
Sydney Brenner: A Biography (11)
Pyrimidine dimer-DNA glycosylases: studies on bacteriophage T4-infected and on uninfected Escherichia coli. (11)
A comprehensive catalogue of somatic mutations in cancer genomes. (10)
Regulation of the yeast RAD2 gene DNA damage-dependent induction correlates with protein binding to regulatory sequences and their deletion influences survival (10)
Translocation events in the evolution of aminoacyl-tRNA synthetases. (10)
Further evidence that UGA does not code for tryptophan. (10)
Mouse Transgenesis Identifies Conserved Functional Enhancers and cis-Regulatory Motif in the Vertebrate LIM Homeobox Gene Lhx2 Locus (10)
Gene complementing xeroderma pigmentosum group A cells maps to distal human chromosome 9q (10)
Characterization of a hypoxia-response element in the Epo locus of the pufferfish, Takifugu rubripes. (10)
A genetic screen to identify sequences that mediate protein oligomerization in Escherichia coli. (10)
A novel bacterial vector system for monitoring protein-protein interactions in the cAMP-dependent protein kinase complex. (10)
Physiological aspects of bacteriophage genetics. (10)
The absolute sign of certain phase-shift mutants in bacteriophage T4. (10)
The intersection between the birth of molecular biology and the discovery of DNA repair. (9)
Dancing with the elephants: envisioning the structural biology of DNA repair pathways. (9)
Humanity As the Model System (9)
Genomic organization of the fungus Phycomyces. (9)
How good a model is the Fugu genome? (9)
A new selective phage cloning vector, lambda 2001, with sites for XbaI, BamHI, HindIII, EcoRI, SstI and XhoI. (9)
Biochemistry strikes back. (9)
A selective λ phage cloning vector with automatic excision of the insert in a plasmid (9)
Cyclostomes Lack Clustered Protocadherins. (8)
The phasmid as a tool for plasmid genetics: I. Fine structure of the β-lactamase gene (8)
The future historian: Reflections on the archives of contemporary sciences. (8)
Multiple PolK (POLK) transcripts in mammalian testis. (8)
Anomalously revertible r II mutants of phage T 4 . (8)
Evidence for inactivation of DNA repair in frozen and thawed mammalian cells. (8)
Inborn Errors of Metabolism (8)
DNA fingerprinting by sampled sequencing. (8)
Human population studies and the World Health Organization. (8)
14 Enzymes That Incise Damaged DNA (8)
Mapping of a single locus capable of complementing the defective heterochromatin phenotype of Roberts syndrome cells. (8)
The role played by endogenous and exogenous electric fields in DNA signaling and repair. (8)
Save your notes, drafts and printouts: today's work is tomorrow's history (7)
The adsorption of bacteriophages by sensitive and resistant cells of Escherichia coli strain B (7)
Short-range linkage relationships of the valyl-tRNA synthetase gene in Fugu rubripes (7)
An interview with... Sydney Brenner. Interview by Errol C. Friedberg. (7)
Genomic structure and sequence of the pufferfish (Fugu rubripes) gene encoding an actin-related protein. (7)
Spontaneous revertants of amber mutants. (7)
Inroads into base excision repair II. The discovery of DNA glycosylases. "An N-glycosidase from Escherichia coli that releases free uracil from DNA containing deaminated cytosine residues," Proc. Nat. Acad. Sci. USA, 1974. (7)
Protein sequencing and the making of molecular genetics. (7)
Cellular responses to DNA damage (7)
Tour de Farce (7)
Serine/threonine phosphatases of the pufferfish, Fugu rubripes. (7)
Call for a cull of pointlessly different reference styles (7)
A selective lambda phage cloning vector with automatic excision of the insert in a plasmid. (7)
Regulatory mutants of dihydrofolate reductase in Escherichia coli K12 (6)
TRYPTOPHAN BIOSYNTHESIS IN Salmonella Typhimurium. (6)
Genetic evidence and interpretation in history (6)
Mapping development or how molecular is molecular biology (6)
Chromosome surveys of human populations: between epidemiology and anthropology. (6)
Hot news: temperature-sensitive humans explain hereditary disease. (6)
8 DNA Excision Repair Pathways (6)
Frederick Sanger (1918–2013) (6)
Nucleotide Excision Repair in Yeast: Recent Progress and Implications (6)
The plasmid as a tool for plasmid genetics. II. Isolation of point mutations that affect replication of a ColE1-related plasmid. (6)
A fragment of the yeast DNA repair protein Rad4 confers toxicity to E. coli and is required for its interaction with Rad7 protein. (6)
Replicating and reshaping DNA: a celebration of the jubilee of the double helix. Perspectives. (6)
Recent Insights on DNA Repair: The Mechanism of Damaged Nucleotide Excision in Eukaryotes and Its Relationship to Other Cellular Processes a (6)
CHAPTER TWELVE. Models and the Making of Molecular Biology (6)
Partial complementation of the UV sensitivity of E. coli and yeast excision repair mutants by the cloned denV gene of bacteriophage T4 (6)
Microcell-mediated chromosome transfer: a strategy for studying the genetics and molecular pathology of human hereditary diseases with abnormal responses to DNA damage. (6)
The ancient molecule (5)
Hunting the Metaphor (5)
The rough and the smooth (5)
Cancer biology : readings from Scientific American (5)
Rous-Whipple Award Lecture. Nucleotide excision repair and cancer predisposition: A journey from man to yeast to mice. (5)
Characterization of the Platelet-derived Growth Factor Receptor Alpha and c-kit Genes in the Pufferfish Fugu rubripes (5)
A life in science (5)
Erratum: Two-polymerase mechanisms dictate error-free and error-prone translesion DNA synthesis in mammals (The EMBO Journal (2009) 28 (992) DOI: 10.1038/emboj.2009.72) (5)
Bacterial Protoplasts (5)
A life in science (5)
Molecular approaches to the study of nucleotide excision repair in eukaryotes. (5)
Relics, replicas and commemorations. (5)
Report of the Working Group on Integrated Translational Research in DNA Repair. (5)
Things and the archives of recent sciences (5)
The RAD3 gene of Saccharomyces cerevisiae: Isolation and characterization of a temperature-sensitive mutant in the essential function and of extragenic suppressors of this mutant (5)
Physician–scientists are needed now more than ever (5)
Demonstration That Thymine Dimers are Excised as Oligonucleotides from Specifically Incised Ultraviolet-Irradiated Deoxyribonucleic Acid (5)
New-opathies: An emerging molecular reclassification of human disease (5)
Cancer predisposition associated with defective DNA repair: studies with mutant mouse strains. (5)
DNA repair mechanisms : [proceedings] (5)
Closing remarks: the genetic outlook. (4)
RAD 9-dependent G 1 arrest defines a second checkpoint for damaged DNA in the cell cycle of Saccharomyces cerevisiae ( UV radiation / DNA repair ) (4)
Value of measurements of DNA repair levels in predicting carcinogenic potential of chemicals (4)
Faculty Opinions recommendation of Lesion bypass in yeast cells: Pol eta participates in a multi-DNA polymerase process. (4)
A Biography of Paul Berg:The Recombinant DNA Controversy Revisited (4)
Comparative analysis of the PCOLCE region in Fugu rubripes using a new automated annotation tool (4)
The Writing Life of James D. Watson (4)
Making Mice: Standardizing Animals for American Biomedical Research, 1900-1955 (review) (4)
Disciplinary histories and the history of disciplines :the challenge of molecular biology (4)
Whose Turn? Chromosome Research and the Study of the Human Genome (4)
Collinearity and the genetic code (4)
Seymour Benzer (1921-2007) - Obituary (4)
Phage escape libraries for checkmate analysis (4)
A putative second adenylate kinase-encoding gene from the yeast Saccharomyces cerevisiae. (4)
Nature′s Gift to Science (Nobel Lecture). (4)
STUDIES ON THE MOLECULAR MECHANISMS OF NUCLEOTIDE EXCISION REPAIR IN UV-IRRADIATED HUMAN CELLS IN CULTURE (4)
DNA Repair-responses to DNA damage and other aspects of genomic stability. A new journal format. (4)
TERF2-XPF: caught in the middle; beginnings from the end. (4)
Dicing with Darwin (4)
Thymine dimer excision by extracts of human cells. (4)
Reminiscences of a long-time colleague and friend, Philip C. Hanawalt. (4)
The Use of Direct Photoreversal of UV-Irradiated DNA for the Demonstration of Pyrimidine Dimer-DNA Glycosylase Activity (4)
Nucleotide excision repair genes from the yeast Saccharomyces cerevisiae. (4)
The enzymology of DNA repair: Introduction (4)
Nonsense mutants and the genetic code. A small piece of molecular genetics. (3)
A novel method for isolation of large insert DNA from recombinant lambda DNA. (3)
repair in yeast The 19 S complex of the proteasome regulates nucleotide excision (3)
TB or Not TB How Mycobacterium tuberculosis May Evade Drug Treatment (3)
Studies on the Enzymology of Excision Repair in Extracts of Mammalian Cells (3)
Genomic structure and sequence analysis of the valyl-tRNA synthetase gene of the Japanese pufferfish, Fugu rubripes. (3)
Xeroderma Pigmentosum — A Human Model of Defective DNA Repair (3)
Dark repair in bacteriophage systems: overview. (3)
Advances in Brief Mutational Inactivation of the Xeroderma Pigmentosum Group C Gene Confers Predisposition to 2-Acetylaminofluorene-induced Liver and Lung Cancer and to Spontaneous Testicular Cancer in Trp 53 2 / 2 Mice 1 (3)
A novel molecular rotor facilitates detection of p53-DNA interactions using the Fluorescent Intercalator Displacement Assay (3)
Distribution of juxtaglomerular granules. A study of mice on a salt-restricted diet. (3)
Sydney Brenner's 10-on-10: The Chronicles of Evolution (3)
Some Footnotes on Protein Synthesis: A Note for the RNA Tie Club (3)
Nucleotide Excision Repair in Eukaryotes (3)
Beyond selfish genes (3)
Obituary: Seymour Benzer (1921–2007) (3)
Multipolar Meiosis in Elephantulus (3)
Rapid Staining of Juxtaglomerular Cell Granules and Renal Tubular Mitochondria for Light Microscopy (3)
Loose end: All the world's a lab … into a Director (3)
DNA polymerase j-dependent DNA synthesis at stalled replication forks is important for CHK 1 activation (3)
Genetic map of the beginning of the rIIB cistron of bacteriophage T4 (3)
What Are the Properties of Genetic RNA?: A Note for the RNA Tie Club (3)
Good news on the horizon: the Open Researcher and Contributor ID (ORCID). (3)
Evidence for a defect in thymine dimer excision in extracts of Xeroderma pigmentosum cells (3)
Moron peer review (3)
Inhibitor of uracil-D10 NA glycosylase induced by bacteriophage PBS2 (3)
Divergent genetic codes (3)
Molecular biology by numbers... (3)
Molecular biology lab (3)
Erratum: Stable and specific association between the yeast recombination and DNA repair proteins RAD1 and RAD10 in vitro (Molecular and Cellular Biology 12:7 (3045)) (3)
Loose end: All the world's a lab … last scene of all (3)
Faculty Opinions recommendation of The fifth essential DNA polymerase phi in Saccharomyces cerevisiae is localized to the nucleolus and plays an important role in synthesis of rRNA. (3)
On the origin of SCPP genes (3)
Basal vertebrates clarify the evolutionary history of ciliopathy-associated genes Tmem138 and Tmem216. (3)
The discovery of enzymatic photoreactivation and the question of priority: the letters of Salvador Luria and Albert Kelner. (3)
Use of plasmid-mediated resistance to the antibiotic G418 for the rapid screening of a yeast mutant library. (2)
Watson and DNA: Making A Scientific Revolution (2)
Excision repair in mammalian cells and the current status of xeroderma pigmentosum. [uv radiation] (2)
Oxygen Radical Effects, Cellular Protection, and Biological Consequences (2)
XPC, a novel lung tumor suppressor gene (2)
Peer review of scientific papers--a never-ending conundrum. (2)
Master Molecule, Heal Thyself (2)
The writing life of James D. Watson: writing and publishing "The Double Helix". (2)
Introduction to special issue on 40 years of DNA repair (2)
Analysis of the essential and excision repair functions of the RAD3 gene of Saccharomyces cerevisiae by mutagenesis (2)
Impact factors-and all that jazz. (2)
Structural Components of Bacteriophage (2)
A closer look at bibliometrics. (2)
A Life of Writing (2)
An investigation of the effect of radioactive labeling of DNA on excision repair in UV-irradiated human fibroblasts. (2)
A life of fixing DNA. (2)
Physical Mapping of the Genome of Rhodobacter Capsulatus (2)
Stanley Cohen (2)
Erratum: Mice defective in the mismatch repair gene Msh2 show increased predisposition to UVB radiation-induced skin cancer (DNA Repair (2002) 1 (929-934) PII: S156878640200143X) (2)
Expression of Wnt signaling skeletal development genes in the cartilaginous fish, elephant shark (Callorhinchus milii). (2)
Loose end: Molecular biology by numbers … one (2)
Special Achievement in Medical Science Award. From cell physiology to cell physiology. (2)
The 2nd US-Japan DNA Repair Meeting, Honolulu, Hawaii, June 4-8, 2004 (2)
Thoughts on genetics at the fin de siècle. (2)
Deoxyribonucleic acid repair in the yeast Saccharomyces cerevisiae (2)
Techniques and applications of microcell-mediated chromosome transfer to mammalian cells. (2)
Molecular biology by numbers … five (2)
Life sentences: Hunters and gatherers (2)
Validation of XP-C pathogenic variations in archival material from a live XP patient. (2)
Things and Data in Recent Biology (2)
Worms and science (2)
Architektur der Proteine Strukturforschung am Laboratory of Molecular Biology in Cambridge (2)
Molecular biology : a selection of papers (2)
Reconstructing life. Molecular biology in postwar Britain (2)
Matthew Meselson (1)
PARTIAL PURIFICATION AND CHARACTERIZATION OF THREE THYMINE DIMER EXCISING ACTIVITIES FROM HUMAN KB CELLS (1)
D.E. Duncan. The Geneticist Who Played Hoops With My DNA—And Other Masterminds From The Frontiers of Biotech, William Morrow/HaperCollins Publishers (ISBN 0 06 053738 8). (1)
Sequence analysis of Mhc class II ß-like fragments in the pufferfish Fugu rubripes (1)
That lonesome grail: The Code of Codes: Scientific and Social Issues in the Human Genome Project. (1)
To sleep, perchance to dream (1)
[MODIFICATIONS OF INDISPENSABLE FUNCTIONS IN THERMOSENSITIVE ESCHCERICHIA COLI MUTANTS. ON A MUTATION PREVENTING REPLICATION OF THE BACTERIAL CHROMOSOME]. (1)
The book of man (1)
Loose Ends ... False Starts (1)
Retraction notice to "The yeast RAD2, but not RAD1, gene is involved in the transcription-coupled repair of thymine glycols" [Mutat. Res. 337 (1995) 169-178]. (1)
Memoirs of a Scientist-Historian (1)
A Yankee in King Gustav's Court (1)
Implementation of encoded combinatorial chemistry (1)
RAD9-dependent G1arrest defines asecond checkpoint for damagedDNA inthecell cycle ofSaccharomyces cerevisiae (1)
Pillars Article: Origin of antibody variation. Nature 1966. 211: 242-243. (1)
DNA polymerases for translesion DNA synthesis: enzyme purification and mouse models for studying their function. (1)
In The Spirit Of Science: Lectures By Sydney Brenner On Dna, Worms And Brains (1)
Corrigendum to “Retraction” [DNA Repair 2 (2003) 361] (1)
PULMONARY ASPERGILLOSIS IN A WHITE SOUTH AFRICAN FARMER. A CASE REPORT. (1)
Life sentences: Elementary Zenetics - do or dai (1)
Genotype-specific Trp 53 Mutational Analysis in Ultraviolet B Radiation-induced Skin Cancers in Xpc and Xpc Trp 53 Mutant Mice 1 (1)
Two‐polymerase mechanisms dictate error‐free and error‐prone translesion DNA synthesis in mammals (1)
Molecular Consequences of the Amber Mutation and its Suppression (1)
Dr. Sydney Brenner on The Next 100 years of Biology (1)
Recycling history (1)
False starts Inverse genetics (1)
How the quest was won (1)
John Kendrew and myoglobin: Protein structure determination in the 1950s (1)
Laboratory of Molecular Biology (LMB) (1)
Faculty Opinions recommendation of The E295K DNA polymerase beta gastric cancer-associated variant interferes with base excision repair and induces cellular transformation. (1)
Sydney Brenner (1927-2019) (1)
Phenotypic Complementation of Cells from Human Hereditary Diseases with Defects in Cellular Responses to DNA Damage, by Single Human Chromosomes (1)
DNA repair synthesis during base excision repair in vitro is catalyzed by DNA polymerase epsilon and is influenced by DNA polymerases alpha and delta in Saccharomyces cerevisiae (1)
Loose ends (1)
Inverse genetics. (1)
A night at the operon (1)
Molecular politics for novices (1)
Rad3 protein of Saccharomyces cerevisiae: Overexpression and preliminary characterization using specific antibodies (1)
The tale of the human genome (1)
That lonesome grail (1)
A Third Watson Memoir. Avoid Boring People-Lessons From a Life in Science, J.D. Watson. A.A. Knopf, New York, NY (2007), ISBN 978-0-375-41284-4 (DOI: 10.1016/j.dnarep.2007.10.006) (1)
Transfection enhancement in Bacillus subtilis displays features of a novel DNA repair pathway. I: DNA base and nucleolytic specificity. (1)
Use of nucleotide excision repair-deficient mice as a model for chemically induced lung cancer. (1)
Mechanisms and consequences of DNA damage processing : proceedings of a director's sponsors-UCLA symposium held at Taos, New Mexico, January 24-30, 1988 (1)
Fixing Your Damaged and Incorrect Genes (1)
THE GENETICS OF CAENORHABDZTZS ELEGANS (1)
Fraud in science--reflections on some whys and wherefores. (1)
The selfish gene at 30: the origin and career of a book and its title (1)
Growth of a journal. (1)
TMV in the Lab and Life Sciences (1)
Scientists’ Lives and the History of Late Twentieth Century Life Sciences (1)
Defining the biochemistry of mismatch repair (1)
UV-induced ubiquitination of RNA polymerase II is deficient in cockayne's syndrome cells (1)
The greatest satisfaction (1)
From cell physiology to cell physiology (1)
Loose end: All the world's a lab … then the full professor (1)
Genomics and a Scientifically Responsible Ethics (1)
Corrigendum: Elephant shark genome provides unique insights into gnathostome evolution (1)
High‐Throughput and Industrial Methods for mRNA Expression Analysis (1)
Reflex: intramolecular barcoding of long-range PCR products for sequencing multiple pooled DNAs (1)
After the (draft) sequence (1)
Confessions of a biologist (1)
Author Correction: Elephant shark genome provides unique insights into gnathostome evolution. (1)
Transfection enhancement in Bacillus subtilis displays features of a novel DNA repair pathway. II: Host constitutive expression, repair DNA synthesis, and in vitro activity. (1)
Vectors lambda 200g and lambda 200c: two useful derivatives of lambda 2001. (1)
Principles of Neural Network Construction (1)
Interview with Sydney Brenner. the world of genome projects. (1)
The decipherment of Linear G (1)
Paul Berg (1)
Journal impact factor, 2004 (1)
Theories of biological pattern formation : a Royal Society discussion held on 25 and 26 March 1981 (1)
A CASE OF HAMMAN-RICH SYNDROME PRESENTING WITH SEVERE WEIGHT LOSS. (0)
Discussion of the Paper (0)
The Lure of Nucleic Acid Enzymology (0)
Faculty Opinions recommendation of Rad18 guides poleta to replication stalling sites through physical interaction and PCNA monoubiquitination. (0)
The adsorption of bacteriophages by sensitive and resistant cells of Escherichia coli strain B (0)
Western Reserve University: Enzymology, intermediary metabolism and the trials of learning how to do a meaningful experiment (0)
Philip Leder (0)
The Essential Paul Berg: A glimpse of the contemporary man (0)
Reflex™: a novel method to sequence barcoded long-range PCR products in a pooled population of hundreds of DNA samples (0)
Translesion DNA synthesis-A fundamental DNA damage tolerance mechanism (0)
RAD4 gene of Saccharomyces cerevisiae: molecular cloning and partial characterization of a gene that is inactivated in Escherichia coli (0)
Chairman's Closing Remarks (0)
Interview of Sydney Brenner (0)
Faculty Opinions recommendation of Mode of inhibition of short-patch base excision repair by thymine glycol within clustered DNA lesions. (0)
The seven deadly curs'd sins … Envy (0)
Loose ends (0)
Loose ends (0)
Friedberg , and the Genesis of Mutations Specialized DNA Polymerases , Cellular Survival (0)
Transcription-coupled Repair as a Biodefence Mechanism (0)
Commercial Ventures and the Founding of DNAX (0)
The buck stops with government (0)
Methode d'etablissement de la cartographie des sites de restriction dans les polynucleotides (0)
Closing Remarks (0)
The Discovery of Ribonuclease P and Enzymatic Activity of Its RNA Subunit (0)
Washington University, St. Louis: Simply stated, I discovered a new kind of reaction (0)
Map of man (0)
A Note on the Archaeology of Groot Marico and Pitsani (0)
Loose end (0)
Loose end (0)
Ochre Mutants, a New Class of Suppressible Nonsense Mutants (0)
Making Recombinant DNA — The First Faltering Steps: One morning Paul and I got together and he suggested trying to put new genes into SV40 (0)
Cellular responses to DNA damage : proceedings of the UCLA symposium held at Keystone, Colorado, April 10-15, 1983 (0)
Nucleotide Excision Repair: Biology (0)
The effect of cycloheximide on semi-conservative DNA synthesis in UV-irradiated human fibroblasts (0)
Centaur biology (0)
Photoreactivation of pyrimidine dimers in human cells (0)
All the world's a lab ... then the assistant professor (0)
Editorial—Dale W. Mosbaugh, 1953–2004 (0)
A Momentous Gordon Research Conference: Well, now we can put together any DNA we want to (0)
RAD3 gene of Saccharomyces cerevisiae: nucleotide sequence of wild-type and mutant alleles, transcript mapping, and aspects of gene regulation (0)
Small molecule insulin mimetics reduce food intake and body weight and prevent development of obesity (0)
141 Rodent complemtation group 8 (ERCC8) corresponds to cockayne syndrome complementation group A (0)
Methode de sequencage de l'adn (0)
Molecular biology by numbers…six (0)
Use of an Escherichia coli mutant strain permits measurement of single-stranded apurinic-apyrimidinic endonuclease in crude extracts: studies with untransformed cells and cells transformed with plasmids containing the uvrC gene (0)
Beyond the Neuro-realism Fallacy: From John Mallard’s Hand-painted MRI Image of a Mouse to BioArt Scenarios (0)
What Genetics Offers Geobiology (0)
Uppsala universitets matrikel 1595-1817 : register (0)
Faculty Opinions recommendation of Multiple interactions of rad23 suggest a mechanism for ubiquitylated substrate delivery important in proteolysis. (0)
Loose Ends (0)
"The Theory of Mutagenesis" [Editorial letter] (0)
Celebrating 40 years of biochemistry in Europe (0)
Loose Ends (0)
Jobs: the need to reach an ideal steady state (0)
The house that Jim built (0)
Nucleic Acids: Chemical Damage (0)
In Support of Basic Science (0)
Harold Varmus (0)
Rigaud and Schmincke Types of Lymphoepithelioma (0)
The perfidy of impact factors. (0)
Faculty Opinions recommendation of Upregulation of error-prone DNA polymerases beta and kappa slows down fork progression without activating the replication checkpoint. (0)
Report to the Medical Research Council on the Work of the Division of Molecular Genetics, now the Division of Cell Biology, from 1961-1971 (0)
Compositions and methods for the reordering of molecular nucleic acid (0)
False starts What lies ahead? (0)
Like Father Like Sons (0)
Erling Christen Seeberg (1946–2004) (0)
Adventures in the golden age of molecular biology. (0)
Destiny rides again (0)
Marshall Nirenberg (0)
Loose ends (0)
Aaron Klug (0)
Enhanced Sensitivity of Csb m/m /Xpa −/− Retinal Photoreceptor Cells to Genotoxic Insults (0)
Mouse mutant database relevant to cellular responses to DNA damage. (0)
Fred Sanger, Double Nobel Laureate: A Biography, by George G. Brownlee. 2014. Cambridge University Press (0)
DNA repair | Nucleotide Excision Repair: Biology (0)
The Controversy Heats Up: I would not do that experiment now! (0)
Procede normalise d'amplification enzymatique de l'adn (0)
Molecular biology by numbers …seven (0)
Faculty Opinions recommendation of Ubiquitin-binding domains in Y-family polymerases regulate translesion synthesis. (0)
Erratum: Editor's Note (DNA Repair (2003) 2 (1157)) (0)
Lawrence Grossman, Ph.D., 1924–2006 (0)
The many faces of DNA p mutagenesis and for mutb (0)
Defective thymine dimerexcision bycell-free extracts ofxeroderma pigmentosium cells (0)
Identity of N2 ochre nonsense mutants. (0)
The Management of Science and the Need for Greater Clarity (0)
Faculty Opinions recommendation of POLQ (Pol theta), a DNA polymerase and DNA-dependent ATPase in human cells. (0)
The Dissenters: A Different Point of View: All I can say today is I was a jackass to sign the “Berg” letter (0)
The Nobel Prize in Chemistry: Let's be absolutely frank about this (0)
Nucleotide excision repair (NER) of DNA-yeast as a eukaryotic model (0)
Asilomar II: An outright ban would be a disaster (0)
Other sciences … the stars look down (0)
Learning About Your Genes (0)
Discovering Transfer RNA: That was my entree to molecular biology (0)
Here, in Kyoto … (0)
A third Watson memoir (0)
Financial conflicts of interest in the scientific publication world--and other good news. (0)
Faculty Opinions recommendation of Identification of TFB5, a new component of general transcription and DNA repair factor IIH. (0)
The Double Helix Revisited – and Much More (0)
Mentioned in Dispatches (0)
Faculty Opinions recommendation of High mobility of flap endonuclease 1 and DNA polymerase eta associated with replication foci in mammalian S-phase nucleus. (0)
Measurement of repair patch size by quantitation of nucleotides excised during DNA repair in vivo (0)
Faculty Opinions recommendation of Xeroderma pigmentosum C is involved in Epstein Barr virus DNA replication. (0)
Loose ends (0)
Original COFS syndrome kindred from Manitoba has a mutation in the cockayne syndrome group B (CSB) gene. (0)
Empty chateaux (0)
DNA Replication — The Holy Grail (0)
Ronald E. Doel and Thomas Söderqvist (eds.) The Historiography of Contemporary Science, Technology, and Medicine: Writing Recent Science . London and New York: Routledge, 2006. Pp. xv+313. ISBN 0-415-39142-3. £80.00 (paperback). (0)
Yet Another Stanford Contribution: I was confident that Paul Berg would support an offer of a faculty position at Stanford (0)
False starts. The book of man. (0)
A method for gene mapping. (0)
The tale of the human genome (0)
Yeast nucleotide excision repair proteins Rad2 and Rad4 interact with RNA polymerase II basal transcription factor b (TFIIH) (0)
Sir John Kendrew (0)
Loose ends (0)
Remembrance of things past… rumination (0)
Faculty Opinions recommendation of Trex1 exonuclease degrades ssDNA to prevent chronic checkpoint activation and autoimmune disease. (0)
All the world's a lab...at first, the graduate student (0)
Faculty Opinions recommendation of DNA polymerase lambda, a novel DNA repair enzyme in human cells. (0)
sequencing methods dns (0)
The End of the Beginning (0)
Note on Sources (0)
Toward an Understanding of Nucleotide Excision Repair in Yeast: A Summary of Recent Progress (0)
Faculty Opinions recommendation of Interaction of human DNA polymerase eta with monoubiquitinated PCNA: a possible mechanism for the polymerase switch in response to DNA damage. (0)
Increased confidence in the identification of alleles with molecular count (0)
“Models”: Diverse but Limited (0)
[Effect of enzymatic induction on the rate of synthesis of a specific messenger RNA in E. coli]. (0)
Watson and DNA: Making A Scientific Revolution: Victor K. McElheny, Perseus Publishing, Cambridge, MA, 2003, ISBN- 0-7382-0341-6 (0)
Loose ends (0)
Book Review: Isozymes: Molecular Structure and Regulation (0)
The Aftermath: Many hours of ensuing discussion and debate (0)
Letter from Sydney Brenner to Joshua Lederberg (0)
Molecular Approaches to Evolution (0)
3. X and Y (0)
Report on the First US-Japan DNA Repair Meeting. Sendai, Japan, October 27-31, 2002. (0)
Repair of DNA (0)
Letter from Sydney Brenner to Dr. W.H. McClain (0)
Faculty Opinions recommendation of Sem1, the yeast ortholog of a human BRCA2-binding protein, is a component of the proteasome regulatory particle that enhances proteasome stability. (0)
Book Review of 'French DNA. Trouble in Purgatory' by P. Rabinow (0)
A retiring fellow (0)
Which Future for Humanity? a Yankee in King Gustav's Court (0)
Faculty Opinions recommendation of Centrin 2 stimulates nucleotide excision repair by interacting with xeroderma pigmentosum group C protein. (0)
False starts All the world’s a lab … and last, The Survivor (0)
Epistemology and history. (0)
Molecular biology by numbers … four (0)
Postcard from Sydney Brenner to Joshua Lederberg (0)
Original COFS syndrome Manitoba Aboriginal kindred has a mutation in the Cockayne syndrome group B (CSB) gene. (0)
5. Of Chromosomes and DNA (0)
Loose Ends From Current Biology (0)
Manners, Good and Bad (0)
Asilomar II — Lessons Learned: The “social contract” between science and the public has served us well for a long time (0)
Apoptosis in Embryonic Development (0)
Letter from Sydney Brenner to Paul Berg (0)
Increasing the reliability of the allele-indications by molecular counting (0)
Book Review:A History of Molecular Biology Michel Morange, Matthew Cobb (0)
Remembrance of things past … Writing (0)
Autobiographical series. (0)
Faculty Opinions recommendation of Structure of the DNA repair helicase XPD. (0)
A history of genetics (0)
Happy 5th birthday, DNA Repair. (0)
Isozymes: Molecular Structure and Regulation: Current Topics in Biological and Medical Research, vol 7. (0)
The Stanford Department of Biochemistry (0)
Susan Lindee.Moments of Truth in Genetic Medicine. xi + 288 pp., figs., bibl., index. Baltimore: Johns Hopkins University Press, 2005. $40 (cloth). (0)
Happy 10th birthday. (0)
Nucleotide excision repair in yeast: recent progress and implications. In DNA Repair (0)
DNA Repair: Editorial (0)
Appendix F: Cloned Eukaryotic DNA (0)
Six months in category four (0)
Public Policy Issues — And Other Interests: Freedom to conduct scientific enquiry is inherent in the right to free speech (0)
Methodes et compositions de marquage et d'identification de polynucleotides (0)
Normal microscopic structure of the kidney as related to function. (0)
Loose ends (0)
1. Radiation and Mutation (0)
Making Recombinant Molecules with Frog DNA: I told Stan that John Morrow had Xenopus DNA (0)
4. Scaling Up (0)
Remembrance of things past … Reading (0)
Twisted strands (0)
The seven deadly curs'd sins … Pride (0)
USEOF "REPORTERGROUPS"INSTRUCTURE-FUNCTION STUDIESOFPROTEINS* (0)
1964 Gordon Research Conference on Nucleic Acids (0)
Diane B. Paul;, Jeffrey P. Brosco.The PKU Paradox: A Short History of a Genetic Disease. (Johns Hopkins Biographies of Disease, 6.) xxiv + 289 pp., illus., bibl., index. Baltimore: Johns Hopkins University Press, 2013. $24.95 (paper). (0)
Emperor Of Enzymes: A Biography Of Arthur Kornberg, Biochemist And Nobel Laureate (0)
Nucleotide excision repair of DNA in the yeast S. cerevisiae (0)
Improvements in the adapters based sequence analysis (0)
A second chapter that I found quite engaging was Steven Shapin’s “Who Is an Industrial Scientist?” Shapin juxtaposes the mid-twentieth-century culture and practice of industrial science as portrayed by academic sociol- (0)
Abstract 1966: In vivo detection of nucleotide lesions preceding mutation fixation (0)
Faculty Opinions recommendation of Lesion (in)tolerance reveals insights into DNA replication fidelity. (0)
Books Received (0)
cerevisiae. I. STUDIES WITH INTACT CELLS AND CELL-FREE SYSTEMS (0)
The 2010 Genetics Society of America Medal: Barbara Meyer (0)
Letter from Sydney Brenner to Francis Crick (0)
2. Chromosomes and the Clinic (0)
The first comprehensive impact factor for DNA Repair (0)
Growing up in Brooklyn: A pretty rambunctious kid (0)
The march of thyme (0)
Erratum: Repair of nitrous acid damage to DNA in Escherichia coli (Biochemistry (1977) 16, 22, (4934-4939)) (0)
Loose ends (0)
Loose ends (0)
Loose ends (0)
New horizons in industrial microbiology : a Royal Society discussion (0)
Monod as the founder of a new discipline: local and international contexts. (0)
Book Review:Picture Control: The Electron Microscope and the Transformation of Biology in America, 1940-1960 Nicolas Rasmussen (0)
DNA Replication Fidelity (0)
Alex Rich (0)
Karen Rader. Making Mice: Standardizing Animals for American Biomedical Research, 1900–1955. Princeton, New Jersey, Princeton University Press, 2004. xviii, 299 pp., illus. $45. (0)
Introduction: Scrutinizing the Data World (0)
Park Doing.Velvet Revolution at the Synchrotron: Biology, Physics, and Change in Science. viii + 155 pp., illus., bibl., index. Cambridge, Mass./London: MIT Press, 2009. $28 (cloth). (0)
Perceptions in science. The making of an icon. (0)
A Life Well Lived (0)
Making Human Populations (0)
Bilaterian phylogenetic trees (0)
Legislative and Revisionist Challenges to Recombinant DNA: You must think me a bloody fool! (0)
Faculty Opinions recommendation of A new, tenth subunit of TFIIH is responsible for the DNA repair syndrome trichothiodystrophy group A. (0)
Obituary: Arthur Kornberg (1918-2007). (0)
The writing life of James D. Watson: Writing The Double Helix (0)
Scientists and Politics (0)
The Discovery of DNA Polymerase (0)
Brief Communication 3 , 4-Epoxy-1-butene , a ReactiveMetabolite of 1 , 3-Butadiene , Induces SomaticMutations in Xpc-nullMice (0)
David Baltimore (0)
Faculty Opinions recommendation of The critical mutagenic translesion DNA polymerase Rev1 is highly expressed during G(2)/M phase rather than S phase. (0)
An Historic Meeting in Hawaii: I’ll Have the Chopped Liver Please (0)
Life in the Test Tube (0)
RAD1 and RAD10 in vitro. yeast recombination and DNA repair proteins Stable and specific association between the (0)
Advances in Protein Chemistry: Preface (0)
EcoRI Restriction Endonuclease — A Major Breakthrough: Therefore, any two DNA molecules with RI sites can be recombined at their restriction sites (0)
Saccharomyces cerevisiae RAD2 gene: isolation, subcloning, and partial characterization (0)
Faculty Opinions recommendation of Analysis of translesion replication across an abasic site by DNA polymerase IV of Escherichia coli. (0)
Nucleotide Excision Repair: Biology (0)
Nucleotide Excision Repair and Cancer Predisposition (0)
The Evolution of the Immune System: An Introduction (0)
Faculty Opinions recommendation of Human DNA polymerase lambda possesses terminal deoxyribonucleotidyl transferase activity and can elongate RNA primers: implications for novel functions. (0)
Faculty Opinions recommendation of BRCA1 induces DNA damage recognition factors and enhances nucleotide excision repair. (0)
A fascinating peek at the impact of molecular biology on the study of human evolution (0)
Faculty Opinions recommendation of DnaE2 polymerase contributes to in vivo survival and the emergence of drug resistance in Mycobacterium tuberculosis. (0)
Hereditary disorders of DNA repair and DNA damage tolerance that predispose to neoplastic transformation (0)
The “Retirement” Years: I expect I’ll be dragged into the fund raising for that project (0)
The molecular basis of mutagenesis - 40 years of research on genomic integrity. (0)
Faculty Opinions recommendation of XPD helicase structures and activities: insights into the cancer and aging phenotypes from XPD mutations. (0)
Growing Up in New York City, Medical School and the United States Navy (0)
The Cori Laboratory — And a Return to the NIH (0)
In vitro studies on the repair of damaged DNA by bacteriophage T4 (0)
DNA polymerase kappa-dependent DNA synthesis at stalled replication forks is required for CHK 1 activation (0)
Life Goes On: But we missed the existence of introns (0)
Construction of a total physical map of Rhizobium SP. NGR234. (0)
Two DNA repair genes associated with lung carcinogenesis (0)
“Coincidence is the Word We Use When We Can't See the Levers and Pulleys”: (Emma Bull, writer) (0)
Dicing with Darwin The molecular mechanisms that allow bacteria selectively to increase the frequency of beneficial mutations are still unclear but the phenomenon can be encompassed within neo-Darwinian, if not the central dogma. (0)
Faculty Opinions recommendation of Solution structure of a viral DNA polymerase X and evidence for a mutagenic function. (0)
The plasmid as a tool for plasmid genetics. I. Fine structure of the beta-lactamase gene. (0)
A New DNA-dependent ATPase Which Polymerase I and Has DNA-unwinding (0)
The current status of nucleotide excision repair in the yeast Saccharomyces cerevisiae (0)
Faculty Opinions recommendation of Sequence context-dependent replication of DNA templates containing UV-induced lesions by human DNA polymerase iota. (0)
Reflections on the 8th international conference on environmental mutagens. (0)
Fugu rubripes Whole-Genome Shotgun Assembly and Analysis of the Genome of (0)
An upwardly mobile impact factor (0)
NU UCLEAR TARGETING SEQUENCES (0)
Copenhagen: The rabbit was not an enthusiastic swimmer (0)
ObituarySeymour Benzer (1921–2007) (0)
DNA Repair in Yeast (0)
Learning from the Masters — The NIH and the Ochoa Laboratory (0)
Erratum: Multiple thymine dimer excising nuclease activities in extracts of human KB cells (Biochemistry (1978) 17, 5, (850-857)) (0)
The 3rd Japan-US DNA Repair Meeting, Sendai, Japan, May 7-11, 2007. (0)
The Recombinant DNA Controversy: The gathering storm (0)
Mutagenesis in the spotlight. (0)
Faculty Opinions recommendation of Impaired expression of NER gene network in sporadic solid tumors. (0)
Transcription and Translation: New Directions: The potential of unraveling the genetic code (0)
Brief reports for DNA repair (0)
Stanford University — and its Refurbished Department of Biochemistry: Kornberg sought to maintain a relatively small faculty (0)
Structure of bacteriophage (0)
Faculty Opinions recommendation of A novel strategy to engineer DNA polymerases for enhanced processivity and improved performance in vitro. (0)
Molecular cloning and nucleotide sequence analysis of the Saccharomyces cerevisiae RAD1 gene (0)
19 DNA Damage and Human Disease (0)
Nina Fedoroff (0)
Spores — A Brief Interlude (0)
Faculty Opinions recommendation of New functions of XPC in the protection of human skin cells from oxidative damage. (0)
Faculty Opinions recommendation of Arginine methylation regulates DNA polymerase beta. (0)
Characterization of a Saccharomyces cerevisiae strain deleted for the RAD27 gene; a structural homolog of the RAD2 nucleotide excision repair gene (0)
Obituary-Ethel Moustacchi (0)
College — and World War II: Proudly in uniform (0)
Stable and specific association between the yeast recombination and DNA repair proteins RAD1 and RAD10 in vitro (0)
Supplementary information in published manuscripts. (0)
Faculty Opinions recommendation of TFIIH contains a PH domain involved in DNA nucleotide excision repair. (0)
Faculty Opinions recommendation of Somatic stem cells and the kinetics of mutagenesis and carcinogenesis. (0)
Human and mouse homologs of Escherichia coli DinB ( DNA polymerase IV ) , members of the UmuC y DinB superfamily (0)
CHROMOSOME REARRANGEMENTS IN CAENORHABDZTZS ELEGANS (0)
Faculty Opinions recommendation of Polyphosphate kinase regulates error-prone replication by DNA polymerase IV in Escherichia coli. (0)
Color figures for DNA Repair covers (0)
Faculty Opinions recommendation of PCNA ubiquitination and REV1 define temporally distinct mechanisms for controlling translesion synthesis in the avian cell line DT40. (0)
Vectors ?200g and ?200c: two useful derivatives of ?2001 (0)
Making Recombinant DNA; A Major Breakthrough: Berg brought his extensive expertise in nucleic acid biochemistry to bear (0)
Parathyroid hormone-related protein genes in chondrichthyan fish (0)
Comparative Endocrinology o f Calcium Regulation — Sunday Comparative Endocrinology Sunday , June 24 , 2007 CE 01 Calcium storage in sarcoplasmic reticulum : The role of calcium pumps and binding proteins during elevated influx in calcifying crayfish (0)
Unveiling the Code of Life Matthew Cobb Life’s Greatest Secret: The Race to Crack the Genetic Code 2015 Basic Books New York, NY, USA 464 pp. $29.99 (0)
Commercializing the Technology: It may completely change the pharmaceutical industry's approach (0)

This paper list is powered by the following services:

Other Resources About Sydney Brenner

en.wikipedia.org

What Schools Are Affiliated With Sydney Brenner?

Sydney Brenner is affiliated with the following schools:

Sydney Brenner's AcademicInfluence.com Rankings