Sylviane Muller
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Researcher ORCID ID = 0000-0002-0481-0620
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Philosophy Biology
Sylviane Muller's Degrees
- PhD Immunology University of Strasbourg
- Doctorate Medicine University of Strasbourg
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(Suggest an Edit or Addition)Sylviane Muller's Published Works
Published Works
- Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (2012) (2913)
- Cellular uptake of functionalized carbon nanotubes is independent of functional group and cell type. (2007) (1009)
- Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 (2021) (811)
- Autoantigen microarrays for multiplex characterization of autoantibody responses (2002) (671)
- Functionalized carbon nanotubes are non-cytotoxic and preserve the functionality of primary immune cells. (2006) (647)
- Immunization with peptide-functionalized carbon nanotubes enhances virus-specific neutralizing antibody responses. (2003) (480)
- The cytopathic effect of HIV is associated with apoptosis. (1991) (381)
- High susceptibility to collagen-induced arthritis in mice lacking IFN-gamma receptors. (1997) (380)
- Asymmetry in Histone H3 variants and lysine methylation between paternal and maternal chromatin of the early mouse zygote (2005) (340)
- CXCR3, Inflammation, and Autoimmune Diseases (2009) (323)
- Endotoxin‐free heat‐shock protein 70 fails to induce APC activation (2002) (274)
- Synthetic peptides as antigens: pitfalls of conjugation methods. (1985) (274)
- Lysosomes as a therapeutic target (2019) (249)
- The SARS-CoV-2 as an instrumental trigger of autoimmunity (2021) (243)
- Acceleration of type 1 diabetes mellitus in proinsulin 2-deficient NOD mice. (2003) (241)
- Cationic carbon nanotubes bind to CpG oligodeoxynucleotides and enhance their immunostimulatory properties. (2005) (236)
- Membrane expression of HIV envelope glycoproteins triggers apoptosis in CD4 cells. (1993) (217)
- HSPA8/HSC70 chaperone protein (2013) (207)
- Neuropsychiatric systemic lupus erythematosus: pathogenesis and biomarkers (2014) (204)
- OX40 Ligand Contributes to Human Lupus Pathogenesis by Promoting T Follicular Helper Response. (2015) (188)
- An Overview of Novel Adjuvants Designed for Improving Vaccine Efficacy. (2017) (178)
- Nucleosomes and histones are present in glomerular deposits in human lupus nephritis. (1995) (160)
- Antigenic mimicry of natural L-peptides with retro-inverso-peptidomimetics. (1994) (152)
- Macroautophagy is deregulated in murine and human lupus T lymphocytes (2012) (147)
- Lupuzor/P140 peptide in patients with systemic lupus erythematosus: a randomised, double-blind, placebo-controlled phase IIb clinical trial (2012) (145)
- Recognition of a subregion of human proinsulin by class I-restricted T cells in type 1 diabetic patients. (2005) (132)
- Anti‐SSA/Ro52 autoantibodies blocking the cardiac 5‐HT4 serotoninergic receptor could explain neonatal lupus congenital heart block (2000) (124)
- Apoptosis-induced acetylation of histones is pathogenic in systemic lupus erythematosus. (2007) (123)
- T cell recognition and therapeutic effect of a phosphorylated synthetic peptide of the 70K snRNP protein administered in MRL/lpr mice (2003) (118)
- Epitope spreading in systemic lupus erythematosus: identification of triggering peptide sequences. (2002) (112)
- Spliceosomal peptide P140 for immunotherapy of systemic lupus erythematosus: results of an early phase II clinical trial. (2008) (111)
- HSC70 blockade by the therapeutic peptide P140 affects autophagic processes and endogenous MHCII presentation in murine lupus (2010) (108)
- Synthetic Polypeptides As Antigens (1988) (98)
- Epigenetic Histone Code and Autoimmunity (2010) (90)
- Comparison of different methods for localizing antigenic regions in histone H2A. (1986) (89)
- Application and limitations of the multiple antigen peptide (MAP) system in the production and evaluation of anti-peptide and anti-protein antibodies. (1992) (89)
- A simple approach to cancer therapy afforded by multivalent pseudopeptides that target cell-surface nucleoproteins. (2011) (88)
- Apoptosis-associated acetylation on histone H2B is an epitope for lupus autoantibodies. (2009) (85)
- D-peptides as immunogens and diagnostic reagents. (1998) (84)
- Neutrophilia and NETopathy as Key Pathologic Drivers of Progressive Lung Impairment in Patients With COVID-19 (2020) (83)
- Apoptosis-induced histone H3 methylation is targeted by autoantibodies in systemic lupus erythematosus (2010) (79)
- Autoantibodies typical of non‐organ‐specific autoimmune diseases in HIV‐seropositive patients (1992) (78)
- A retro-inverso peptide corresponding to the GH loop of foot-and-mouth disease virus elicits high levels of long-lasting protective neutralizing antibodies. (1997) (78)
- Neuropsychiatric systemic lupus erythematosus and cognitive dysfunction: the MRL-lpr mouse strain as a model. (2014) (75)
- Modulation of deregulated chaperone-mediated autophagy by a phosphopeptide (2015) (74)
- The caveolin-1 binding domain of HIV-1 glycoprotein gp41 is an efficient B cell epitope vaccine candidate against virus infection. (2004) (72)
- Antigenicity and immunogenicity of modified synthetic peptides containing D-amino acid residues. Antibodies to a D-enantiomer do recognize the parent L-hexapeptide and reciprocally. (1993) (72)
- T cell recognition and therapeutic effect of a phosphorylated synthetic peptide of the 70K snRNP protein administered in MR/lpr mice. (2003) (71)
- The autoimmune response to chromatin antigens in systemic lupus erythematosus: autoantibodies against histone H1 are a highly specific marker for SLE associated with increased disease activity (2002) (71)
- Presence of antibodies to ubiquitin during the autoimmune response associated with systemic lupus erythematosus. (1988) (68)
- Detection of nucleosome particles in serum and plasma from patients with systemic lupus erythematosus using monoclonal antibody 4H7. (2001) (67)
- Deimination of linker histones links neutrophil extracellular trap release with autoantibodies in systemic autoimmunity (2014) (65)
- Antigenic properties and protective capacity of a cyclic peptide corresponding to site A of influenza virus haemagglutinin. (1990) (65)
- Nucleic acid-associated autoantigens: pathogenic involvement and therapeutic potential. (2010) (64)
- Citrullinated Autoantigens: From Diagnostic Markers to Pathogenetic Mechanisms (2015) (63)
- The Spliceosomal Phosphopeptide P140 Controls the Lupus Disease by Interacting with the HSC70 Protein and via a Mechanism Mediated by γδ T Cells (2009) (62)
- Murine models of systemic lupus erythematosus: B and T cell responses to spliceosomal ribonucleoproteins in MRL/Fas(lpr) and (NZB x NZW)F(1) lupus mice. (2001) (62)
- HIV-1 Tat protein directly induces mitochondrial membrane permeabilization and inactivates cytochrome c oxidase (2012) (59)
- Recognition of synthetic peptides of Sm‐D autoantigen by lupus sera (1990) (58)
- Hepatoma tissue culture (HTC) cells as a model for investigating the effects of low concentrations of herbicide on cell structure and function. (2008) (57)
- Transcutaneous immunization with tetanus toxoid and mutants of Escherichia coli heat-labile enterotoxin as adjuvants elicits strong protective antibody responses. (2003) (57)
- Autophagy as an emerging target for COVID-19: lessons from an old friend, chloroquine (2020) (57)
- Immunization onto bare skin with heat‐labile enterotoxin of Escherichia coli enhances immune responses to coadministered protein and peptide antigens and protects mice against lethal toxin challenge (2001) (56)
- Selective Modulation of CD4+ T Cells from Lupus Patients by a Promiscuous, Protective Peptide Analog1 (2005) (56)
- B and T cell immune response to small nuclear ribonucleoprotein particles in lupus mice: autoreactive CD4+ T cells recognize a T cell epitope located within the RNP80 motif of the 70K protein (2000) (56)
- Early Differentiated CD138highMHCII+IgG+ Plasma Cells Express CXCR3 and Localize into Inflamed Kidneys of Lupus Mice (2013) (55)
- Pathogenic anti-nucleosome antibodies (2008) (55)
- HSPA8/HSC70 in Immune Disorders: A Molecular Rheostat that Adjusts Chaperone-Mediated Autophagy Substrates (2019) (54)
- A lipoyl synthetic octadecapeptide of dihydrolipoamide acetyltransferase specifically recognized by anti-M2 autoantibodies in primary biliary cirrhosis. (1992) (54)
- Function of CD4+,CD25+ Treg cells in MRL/lpr mice is compromised by intrinsic defects in antigen-presenting cells and effector T cells. (2008) (53)
- 52-kDa Ro/SSA epitopes preferentially recognized by antibodies from mothers of children with neonatal lupus and congenital heart block (2005) (53)
- IgG antibodies from patients with primary Sjögren's syndrome and systemic lupus erythematosus recognize different epitopes in 60‐kD SSA/Ro protein (1992) (53)
- Immunization onto bare skin with synthetic peptides: immunomodulation with a CpG‐containing oligodeoxynucleotide and effective priming of influenza virus‐specific CD4+ T cells (2002) (52)
- Recognition of Human Proinsulin Leader Sequence by Class I–Restricted T-Cells in HLA-A*0201 Transgenic Mice and in Human Type 1 Diabetes (2009) (52)
- Glomerular immune deposits in murine lupus models may contain histones (1992) (51)
- Mapping of epitopes on Ul snRNP polypeptide A with synthetic peptides and autoimmune sera (1991) (51)
- Reactivity of autoantibodies in systemic lupus erythematosus with synthetic core histone peptides. (1989) (51)
- Pharmacological regulators of autophagy and their link with modulators of lupus disease (2014) (51)
- Immunochemical localization of the C‐terminal hexapeptide of histone H3 at the surface of chromatin subunits. (1982) (50)
- Importance of spliceosomal RNP1 motif for intermolecular T-B cell spreading and tolerance restoration in lupus (2007) (50)
- Induction of immune response against a short synthetic peptide antigen coupled to small neutral liposomes containing monophosphoryl lipid A. (1993) (50)
- Manipulating Autophagic Processes in Autoimmune Diseases: A Special Focus on Modulating Chaperone-Mediated Autophagy, an Emerging Therapeutic Target (2015) (49)
- Peptide-based approaches to treat lupus and other autoimmune diseases. (2012) (49)
- Synthetic peptides as antigens (1999) (49)
- Immunity under the skin: potential application for topical delivery of vaccines. (2003) (48)
- Specificity of antibodies raised against triacetylated histone H4. (1987) (47)
- In vivo T helper cell response to retro-inverso peptidomimetics. (1997) (47)
- The lupus erythematosus cell phenomenon: comparative analysis of antichromatin antibody specificity in lupus erythematosus cell-positive and -negative sera. (2000) (47)
- Use of histone antibodies for studying chromatin topography and the phosphorylation of chromatin subunits. (1984) (47)
- Partially modified retro-inverso pseudopeptides as non-natural ligands for the human class I histocompatibility molecule HLA-A2. (1996) (47)
- T Cell Response to Preproinsulin I and II in the Nonobese Diabetic Mouse1 (2002) (46)
- Interfacing Functionalized Carbon Nanohorns with Primary Phagocytic Cells (2008) (45)
- Autophagy in neuroinflammatory diseases. (2017) (44)
- Key Sequences Involved in the Spreading of the Systemic Autoimmune Response to Spliceosomal Proteins (2001) (44)
- The HIV-1 transcriptional activator Tat has potent nucleic acid chaperoning activities in vitro (2008) (43)
- A branched, synthetic octapeptide of ubiquitinated histone H2A as target of autoantibodies (1989) (42)
- Mapping of linear histone regions exposed at the surface of the nucleosome in solution. (1997) (42)
- Apoptosis-linked changes in the phosphorylation status and subcellular localization of the spliceosomal autoantigen U1-70K (2008) (41)
- TREM-1 Inhibition Restores Impaired Autophagy Activity and Reduces Colitis in Mice (2018) (41)
- Immunochemical detection of changes in chromatin subunits induced by histone H4 acetylation. (1982) (40)
- Aberrant Expression of the Autoantigen Heterogeneous Nuclear Ribonucleoprotein-A2 (RA33) and Spontaneous Formation of Rheumatoid Arthritis-Associated Anti-RA33 Autoantibodies in TNF-α Transgenic Mice1 (2005) (40)
- Antigenic structure of histone H2B. (1985) (39)
- The mechanism of HIV-1 Tat-directed nucleic acid annealing supports its role in reverse transcription. (2010) (39)
- Autophagy: A new concept in autoimmunity regulation and a novel therapeutic option. (2018) (39)
- Antibodies from patients with rheumatoid arthritis and juvenile chronic arthritis analyzed with core histone synthetic peptides. (1990) (39)
- The LTR72 Mutant of Heat-Labile Enterotoxin of Escherichia coli Enhances the Ability of Peptide Antigens To Elicit CD4+ T Cells and Secrete Gamma Interferon after Coapplication onto Bare Skin (2002) (38)
- Parameters affecting the immunogenicity of a liposome‐associated synthetic hexapeptide antigen (1991) (38)
- The bare skin and the nose as non-invasive routes for administering peptide vaccines. (2001) (37)
- Effect of Skin Barrier Disruption on Immune Responses to Topically Applied Cross-Reacting Material, CRM197, of Diphtheria Toxin (2005) (37)
- Automatic Sequence Design of Major Histocompatibility Complex Class I Binding Peptides Impairing CD8+ T Cell Recognition* 210 (2003) (37)
- Autoantibodies against Modified Histone Peptides in SLE Patients Are Associated with Disease Activity and Lupus Nephritis (2016) (37)
- What Has Come out from Phytomedicines and Herbal Edibles for the Treatment of Cancer? (2018) (37)
- CD4 T cell autophagy is integral to memory maintenance (2018) (36)
- Improvement of collagen-induced arthritis by active immunization against murine IL-1beta peptides designed by molecular modelling. (2005) (36)
- Molecular therapies for systemic lupus erythematosus: clinical trials and future prospects (2009) (36)
- Inhibition of HIV infection by pseudopeptides blocking viral envelope glycoprotein-mediated membrane fusion and cell death. (1996) (36)
- From Systemic Inflammation to Neuroinflammation: The Case of Neurolupus (2018) (35)
- B and T Cell Responses to the Spliceosomal Heterogeneous Nuclear Ribonucleoproteins A2 and B1 in Normal and Lupus Mice1 (2000) (35)
- ATG5 is required for B cell polarization and presentation of particulate antigens (2018) (35)
- Single Insulin-Specific CD8+ T Cells Show Characteristic Gene Expression Profiles in Human Type 1 Diabetes (2011) (35)
- Longitudinal analysis of antibodies to histones, Sm-D peptides and ubiquitin in the serum of patients with systemic lupus erythematosus, rheumatoid arthritis and tuberculosis. (1990) (34)
- Rescue of autophagy and lysosome defects in salivary glands of MRL/lpr mice by a therapeutic phosphopeptide. (2018) (34)
- Selective induction of protection against influenza virus infection in mice by a lipid-peptide conjugate delivered in liposomes. (1994) (34)
- Identification of a Minimal T Cell Epitope Recognized by Antinucleosome Th Cells in the C-Terminal Region of Histone H41 (2000) (33)
- A partially modified retro-inverso pseudopeptide modulates the cytokine profile of CTL specific for an influenza virus epitope. (1998) (33)
- Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356 (2016) (33)
- The cell nuclei of skeletal muscle cells are transcriptionally active in hibernating edible dormice (2009) (32)
- Solid-phase synthesis of "mixed" peptidomimetics using Fmoc-protected aza-beta3-amino acids and alpha-amino acids. (2005) (32)
- Active immunization against murine TNFalpha peptides in mice: generation of endogenous antibodies cross-reacting with the native cytokine and in vivo protection. (2004) (32)
- New Zealand white rabbits immunized with RNA‐complexed total histones develop an autoimmune‐like response (1991) (32)
- Decision-making at the surface of the intact or barrier disrupted skin: potential applications for vaccination or therapy (2005) (32)
- Intramolecular T cell spreading in unprimed MRL/lpr mice: importance of the U1-70k protein sequence 131-151. (2004) (32)
- Editorial :Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). DOI: 10.1080/15548627.2015.1100356;WOS:000373595400001; 2-s2.0-85013763791&;PMID: 26799652 (2016) (31)
- Identification of New Pathogenic Players in Lupus: Autoantibody-Secreting Cells Are Present in Nephritic Kidneys of (NZBxNZW)F1 Mice (2010) (31)
- Assessing Autophagy in Mouse Models and Patients with Systemic Autoimmune Diseases (2017) (30)
- The double reactivity of a human monoclonal rheumatoid factor to IgG and histones is related to distinct binding sites (1988) (30)
- Modulation of immune responses with transcutaneously deliverable adjuvants. (2004) (30)
- CD4+ T Cells from (New Zealand Black × New Zealand White)F1 Lupus Mice and Normal Mice Immunized Against Apoptotic Nucleosomes Recognize Similar Th Cell Epitopes in the C Terminus of Histone H31 (2003) (30)
- Autoimmunity, neuroinflammation, pathogen load: A decisive crosstalk in neuropsychiatric SLE. (2016) (29)
- Enhanced immunogenicity and cross-reactivity of retro-inverso peptidomimetics of the major antigenic site of foot-and-mouth disease virus. (1995) (28)
- Mapping of linear epitopes of human histone H1 recognized by rabbit anti-H1/H5 antisera and antibodies from autoimmune patients. (1994) (28)
- Disease Progression in MRL/lpr Lupus-Prone Mice Is Reduced by NCS 613, a Specific Cyclic Nucleotide Phosphodiesterase Type 4 (PDE4) Inhibitor (2012) (28)
- Nuclei of aged myofibres undergo structural and functional changes suggesting impairment in RNA processing. (2009) (28)
- The HB-19 pseudopeptide 5[Kpsi(CH2N)PR]-TASP inhibits attachment of T lymophocyte- and macrophage-tropic HIV to permissive cells. (2000) (28)
- Diminution of Circulating CD4+CD25high T Cells in Naïve Crohn’s Disease (2009) (27)
- Pharmacological Autophagy Regulators as Therapeutic Agents for Inflammatory Bowel Diseases. (2019) (27)
- Structure of antibody-bound peptides and retro-inverso analogues. A transferred nuclear Overhauser effect spectroscopy and molecular dynamics approach. (2001) (27)
- Immunogenicity of free histones and of histones complexed with RNA. (1991) (26)
- The N-terminus of HIV-1 Tat protein is essential for Tat-TAR RNA interaction (2005) (26)
- Expression of Preproinsulin-2 Gene Shapes the Immune Response to Preproinsulin in Normal Mice1 (2004) (26)
- A retro-inverso peptide analogue of influenza virus hemagglutinin B-cell epitope 91-108 induces a strong mucosal and systemic immune response and confers protection in mice after intranasal immunization. (2002) (26)
- Isolation of histones and related chromatin structures from spermatozoa nuclei of a dasyurid marsupial, Sminthopsis crassicaudata. (1997) (26)
- Successful induction of protective antibody responses against Haemophilus influenzae type b and diphtheria after transcutaneous immunization with the glycoconjugate polyribosyl ribitol phosphate-cross-reacting material 197 vaccine. (2004) (26)
- Mimotopes for lupus-derived anti-DNA and nucleosome-specific autoantibodies selected from random peptide phage display libraries: facts and follies. (2005) (26)
- Direct Visualization of Peptide/MHC Complexes at the Surface and in the Intracellular Compartments of Cells Infected In Vivo by Leishmania major (2010) (26)
- A therapeutic peptide in lupus alters autophagic processes and stability of MHCII molecules in MRL/lpr B cells (2011) (25)
- Lupus Regulator Peptide P140 Represses B Cell Differentiation by Reducing HLA Class II Molecule Overexpression (2018) (25)
- Localization of two antigenic determinants in histone H4. (1983) (25)
- In Vivo Remodeling of Altered Autophagy-Lysosomal Pathway by a Phosphopeptide in Lupus (2020) (25)
- Comparison of two different methods using overlapping synthetic peptides for localizing linear B cell epitopes in the U1 snRNP-C autoantigen. (1996) (24)
- Rituximab treatment overcomes reduction of regulatory iNKT cells in patients with rheumatoid arthritis. (2010) (24)
- The potential of retro-inverso peptides as synthetic vaccines. (1998) (24)
- Delineation of a neutralizing subregion within the immunodominant epitope (GH loop) of foot-and-mouth disease virus VP1 which does not contain the RGD motif. (1999) (24)
- Pre-mRNA Processing Is Partially Impaired in Satellite Cell Nuclei from Aged Muscles (2010) (24)
- Protection of swine from foot-and-mouth disease with one dose of an all-D retro peptide. (1999) (24)
- Recent advances in solid-phase peptide synthesis and preparation of antibodies to synthetic peptides. (1990) (24)
- Peptide-based immunotherapy of systemic lupus erythematosus. (2004) (23)
- Modulation of microtubule assembly by the HIV-1 Tat protein is strongly dependent on zinc binding to Tat (2008) (23)
- Oxidation and mitochondrial origin of NET DNA in the pathogenesis of lupus (2016) (23)
- B cell epitopes of the heterogeneous nuclear ribonucleoprotein A2: identification of a new specific antibody marker for active lupus disease (2008) (22)
- Characterization of a monoclonal antibody reacting with histone H3 (1985) (22)
- Progress and Challenges in the Use of MAP1LC3 as a Legitimate Marker for Measuring Dynamic Autophagy In Vivo (2020) (22)
- Haemolysin‐derived synthetic peptides with pore‐forming and haemolytic activity (1992) (22)
- All-D peptides recognized by an anti-carbohydrate antibody identified from a positional scanning library. (1998) (22)
- Blocking nuclear export of HSPA8 after heat shock stress severely alters cell survival (2018) (21)
- An autophagy-targeting peptide to treat chronic inflammatory demyelinating polyneuropathies. (2018) (21)
- Structural limitations to antigenic mimicry achievable with retroinverso (all-D-retro) peptides. (1996) (21)
- Role of peptide backbone in T cell recognition. (1999) (21)
- Parkinson's disease is an autoimmune disease: A reappraisal. (2020) (21)
- The binding affinity of double‐stranded RNA motifs to HIV‐1 Tat protein affects transactivation and the neutralizing capacity of anti‐Tat antibodies elicited after intranasal immunization (2005) (21)
- Histones and DNA ultrastructural distribution in plant cell nucleus: a combination of immunogold and cytochemical methods. (1998) (21)
- Heteroclitic properties of mixed α-and aza-β3-peptides mimicking a supradominant CD4 T cell epitope presented by nucleosome (2007) (21)
- Targeting VEGF-A with a vaccine decreases inflammation and joint destruction in experimental arthritis (2015) (21)
- Generation and Characterization of Neutralizing Human Monoclonal Antibodies against Human Immunodeficiency Virus Type 1 Tat Antigen (2004) (20)
- A synthetic HIV‐1 Tat protein breaches the skin barrier and elicits Tat‐neutralizing antibodies and cellular immunity (2004) (20)
- Important B-cell epitopes for neutralization of human immunodeficiency virus type 1 Tat in serum samples of humans and different animal species immunized with Tat protein or peptides. (2004) (20)
- Use of an immobilized enzyme and specific antibodies to analyse the accessibility and role of histone tails in chromatin structure. (1990) (20)
- Resetting the autoreactive immune system with a therapeutic peptide in lupus (2015) (20)
- The V3 loop-mimicking pseudopeptide 5[Kpsi(CH2N)PR]-TASP inhibits HIV infection in primary macrophage cultures. (1999) (20)
- Spliceosomal Peptide P 140 for Immunotherapy of Systemic Lupus Erythematosus Results of an Early Phase II Clinical Trial (2008) (20)
- Transcutaneous Immunization with Cross-Reacting Material CRM197 of Diphtheria Toxin Boosts Functional Antibody Levels in Mice Primed Parenterally with Adsorbed Diphtheria Toxoid Vaccine (2008) (19)
- Correction of autophagy impairment inhibits pathology in the NOD.H-2h4 mouse model of primary Sjögren's syndrome. (2020) (18)
- Structural and immunological characterisation of heteroclitic peptide analogues corresponding to the 600-612 region of the HIV envelope gp41 glycoprotein. (2002) (18)
- Human antinuclear autoantibodies crossreacting with the plasma membrane and the N-terminal region of histone H2B. (1987) (18)
- A peptide vaccine administered transcutaneously together with cholera toxin elicits potent neutralising anti-FMDV antibody responses. (2005) (18)
- Adamantane-based dendrons for trimerization of the therapeutic P140 peptide. (2014) (18)
- Accessibility and structural role of histone domains in chromatin. biophysical and immunochemical studies of progressive digestion with immobilized proteases. (1990) (18)
- The importance of implementing proper selection of excipients in lupus clinical trials (2014) (17)
- Specificity and effect on apoptosis of Tat antibodies from vaccinated and SHIV-infected rhesus macaques and HIV-infected individuals. (2003) (17)
- Induction of monocyte chemoattractant protein-1 (MCP-1/CCL2) gene expression by human immunodeficiency virus-1 Tat in human astrocytes is CDK9 dependent (2010) (17)
- Molecular mimicry between SARS‐CoV‐2 and the female reproductive system (2021) (17)
- Applying peptide antigens onto bare skin: induction of humoral and cellular immune responses and potential for vaccination. (2002) (17)
- Ikaros Is a Negative Regulator of B1 Cell Development and Function* (2016) (17)
- Anti-nucleosome antibodies and T-cell response in systemic lupus erythematosus. (2002) (16)
- B and T Cell Responses to the Spliceosomal Heterogeneous Nuclear Ribonucleoproteins A2 and B1 in Normal and Lupus Mice (2000) (16)
- Nuclei of aged myofibres undergo structural and functional changes suggesting impairment in RNA processing (2009) (16)
- Immunomodulation by maternal autoantibodies of the fetal serotoninergic 5-HT4 receptor and its consequences in early BALB/c mouse embryonic development (2007) (16)
- IgG autoantibody response in HTLV-I-infected patients. (1995) (16)
- TLR2 ligation protects effector T cells from regulatory T-cell mediated suppression and repolarizes T helper responses following MVA-based cancer immunotherapy (2012) (16)
- Emerging peptide therapeutics for inflammatory autoimmune diseases. (2010) (16)
- Antitumor vaccination using a major histocompatibility complex (MHC) class I-restricted pseudopeptide with reduced peptide bond. (2000) (15)
- Post-translational modifications, subcellular relocation and release in apoptotic microparticles: apoptosis turns nuclear proteins into autoantigens. (2010) (15)
- Anti-melanocortin-4 receptor autoantibodies in obesity. (2009) (15)
- Influenza Virus-Induced Type I Interferon Leads to Polyclonal B-Cell Activation but Does Not Break Down B-Cell Tolerance (2007) (15)
- Multiple autoepitope presentation for specific detection of antibodies in primary biliary cirrhosis (1992) (15)
- Immunoprevalence of the CD4+ T‐cell response to HIV Tat and Vpr proteins is provided by clustered and disperse epitopes, respectively (2008) (15)
- Tat-neutralizing versus Tat-protecting antibodies in rhesus macaques vaccinated with Tat peptides. (2005) (15)
- Histone Autoantibodies Other Than (H2A-H2B)-DNA Autoantibodies (1996) (15)
- The Mitochondrion-lysosome Axis in Adaptive and Innate Immunity: Effect of Lupus Regulator Peptide P140 on Mitochondria Autophagy and NETosis (2018) (14)
- Lysosomes in acute myeloid leukemia: potential therapeutic targets? (2021) (14)
- Receptor–ligand and parasite protein–protein interactions in Plasmodium vivax: Analysing rhoptry neck proteins 2 and 4 (2018) (14)
- A flavivirus protein M-derived peptide directly permeabilizes mitochondrial membranes, triggers cell death and reduces human tumor growth in nude mice (2009) (14)
- An active mechanism flanks and modulates the export of the small ribosomal subunits (2009) (14)
- Autophagy-Lysosomal Pathway as Potential Therapeutic Target in Parkinson’s Disease (2021) (14)
- Anti-Ro(SSA) and anti-La(SSB) antibodies in autoimmune rheumatic diseases (1994) (13)
- Antibodies to histones in rheumatoid arthritis. (1988) (13)
- Highly specific, cross-reactive sequences recognized by an anti-HBsAg antibody identified from a positional scanning synthetic combinatorial library. (1996) (12)
- Laboratory protocols for the identification of Th cell epitopes on self-antigens in mice with systemic autoimmune diseases. (2000) (12)
- Use of antihistone antibodies with nucleosomes. (1989) (12)
- Peptido-targeting of the mitochondrial transition pore complex for therapeutic apoptosis induction. (2006) (12)
- MHC class II gene associations with autoantibodies to U1A and SmD1 proteins. (1999) (12)
- At least three linear regions but not the zinc-finger domain of U1C protein are exposed at the surface of the protein in solution and on the human spliceosomal U1 snRNP particle. (1998) (11)
- Novel trisaccharide based phospholipids as immunomodulators. (2019) (11)
- Capability of Neutrophils to Form NETs Is Not Directly Influenced by a CMA-Targeting Peptide (2017) (11)
- An Autophagy Modulator Peptide Prevents Lung Function Decrease and Corrects Established Inflammation in Murine Models of Airway Allergy (2021) (11)
- Serological abnormalities, including common idiotype PR4, in families with rheumatoid arthritis. (1989) (10)
- Mimicry of viral epitopes with retro-inverso peptides of increased stability. (1996) (10)
- Epigenetics of Autoantigens: New Opportunities for Therapy of Autoimmune Diseases (2013) (10)
- Interaction between certain major histocompatibility complex class II and T-cell receptor V beta alleles promotes the antibody production to extractable nuclear antigen-related peptides. (1997) (9)
- Selective Modulation of CD 4 T Cells from Lupus Patients by a Promiscuous , Protective Peptide Analog 1 (2005) (9)
- CD4 T Cells from (New Zealand Black New Zealand White)F1 Lupus Mice and Normal Mice Immunized Against Apoptotic Nucleosomes Recognize Similar Th Cell Epitopes in the C Terminus of Histone H3 (2003) (9)
- pH-induced conformational changes in chromatin subunits measured by circular dichroism and immunochemical reactivity (1985) (9)
- Assessing Autophagy in Sciatic Nerves of a Rat Model that Develops Inflammatory Autoimmune Peripheral Neuropathies (2017) (9)
- Regulatory T Cells and Systemic Lupus Erythematosus (2007) (8)
- Synthesis and antigenic properties of reduced peptide bond pseudopeptide analogues of a histone H3 hexapeptide. (1994) (8)
- HIV‐1 neutralizing antibodies elicited by the candidate CBD1 epitope vaccine react with the conserved caveolin‐1 binding motif of viral glycoprotein gp41 (2006) (8)
- Immunization of rabbits with spermine induces antibodies to self antigens. (1993) (8)
- Heteroclitic properties of mixed alpha- and aza-beta3-peptides mimicking a supradominant CD4 T cell epitope presented by nucleosome. (2007) (8)
- Autoantibodies against galectin-2 peptides as biomarkers for the antiphospholipid syndrome (2012) (8)
- Cyclic GMP catabolism up-regulation in MRL/lpr lupus-prone mice is associated with organ remodeling. (2014) (7)
- Immunomodulatory consequences of ODN CpG-polycation complexes. (2009) (7)
- Anti-“dividing cell antigen” autoantibody: A novel antinuclear antibody pattern related to histones in systemic lupus erythematosus (1993) (7)
- Single Insulin-Speci fi c CD 8 + T Cells Show Characteristic Gene Expression Pro fi les in Human Type 1 Diabetes (2011) (7)
- Early Apoptotic Reorganization of Spliceosomal Proteins Involves Caspases, CAD and Rearrangement of NuMA (2012) (7)
- Nanomaterials, Autophagy, and Lupus Disease (2016) (7)
- Immunogenic properties of an anti-DNA antibody-derived peptide, 88H.64-80: location of a dominant idiotope defined by T and B cells. (1998) (6)
- Transcriptionally inactive micronuclei, macronuclear anlagen and transcriptionally active macronuclei differ in histone composition in the hypotrichous ciliateStylonychia lemnae (1990) (6)
- Implication of a lysosomal antigen in the pathogenesis of lupus erythematosus. (2021) (5)
- Characterization of monoclonal antibodies against alpha-hemolysin of Escherichia coli (1991) (5)
- [Autophagy in T and B cell homeostasis: recycling for sustainable growth]. (2016) (5)
- The pharmacokinetics of 124I-rituximab in patients with rheumatoid arthritis (2011) (5)
- Peptide-based therapy in lupus: promising data. (2007) (5)
- Targeting the endo-lysosomal autophagy pathway to treat inflammatory bowel diseases. (2022) (5)
- P140 Peptide Leads to Clearance of Autoreactive Lymphocytes and Normalizes Immune Response in Lupus-Prone Mice (2022) (4)
- Peptide Nanostructured Conjugates for Therapeutics (2013) (4)
- Interplay of four idiotypes and interaction with autoantibodies in lupus patients, their relatives and their spouses. (1996) (4)
- Generation of self-peptides to treat systemic lupus erythematosus. (2014) (4)
- Use of synthetic peptides for the analysis of B-cell epitopes in autoantigens (1994) (4)
- Excipients: not so inert? When the excipient plays the role of an active substance, as exemplified by systemic lupus. (2018) (3)
- Histone deposition and metabolism in embryonic chick lenses during differentiation. (1992) (3)
- Specificity of Anti-Histone Autoantibodies in Systemic Rheumatic Disease (1988) (3)
- Autoantibodies to hnRNP-A2 in SLE: identification of disease-specific linear epitopes and correlation with disease activity and clinical features (2003) (3)
- Dendrimers in immunotherapy and hormone therapy (2020) (3)
- The Therapeutic Effect of Phosphopeptide P140 Attenuates Inflammation Induced by Uric Acid Crystals in Gout Arthritis Mouse Model (2022) (3)
- Synthetic peptides as tools for diagnosis and therapeutic strategies to treat systemic lupus erythematous. (2012) (3)
- Active immunization with anti-DNA autoantibody idiopeptide 88H.64-80 is nephritogenic in (NZB x NZW)F1 and Balb/c mice. (1997) (2)
- Immunologically Inert Nanostructures as Selective Therapeutic Tools in Inflammatory Diseases (2021) (2)
- Autoantibodies against SUMO1-DHX35 in long-COVID (2022) (2)
- LL-37, a Multi-Faceted Amphipathic Peptide Involved in NETosis (2022) (2)
- [Autophagy, autoimmunity and autoimmune diseases]. (2017) (2)
- The potential of retro-inverso peptides as synthetic vaccines. (1998) (2)
- 22 – HISTONE AUTOANTIBODIES (2007) (2)
- Therapeutic effects of peptide P140 in a mouse periodontitis model (2022) (2)
- The Antigenic Structure of Histones (1985) (1)
- A Selective Neutraligand for CXCL12/SDF-1α With Beneficial Regulatory Functions in MRL/Lpr Lupus Prone Mice (2021) (1)
- Target Autophagy as a Novel Therapeutic Strategy in Autoimmune Diseases (2016) (1)
- [Histones and anti-histone antibodies]. (1987) (1)
- A1.36 Active immunisation against peptides of vegf improves joint inflammation and destruction in collagen-induced arthritis (2014) (1)
- HIV-1 Tat and Apoptotic Death (2005) (1)
- CIDP: Current Treatments and Identification of Targets for Future Specific Therapeutic Intervention (2022) (1)
- On the potential of retro-inverso peptides in vaccine design (1998) (1)
- Multiple Antigen Peptide (MAP) System: Detailed Study of Immunogenic and Antigenic Properties, (1992) (1)
- [Soluble tumor necrosis factor receptors in patients with systemic lupus erythematosus]. (1998) (1)
- Immunological and translational key challenges in systemic lupus erythematosus: A symposium update. (2023) (1)
- Disulphide dimerised peptide creates a crystal contact in an anti-peptide antibody. (2002) (1)
- Retropeptides, antibodies directed against the latter, and their use for immunization and the in vitro diagnosis. (1994) (0)
- Blocking nuclear export of HSPA8 after heat shock stress severely alters cell survival (2018) (0)
- The therapeutic P140 peptide, a new immunomodulating tool for lupus may have applications in other chronic inflammatory conditions (2016) (0)
- SYNTHETIC PEPTIDE CORRESPONDING TO THE MAJOR IMMUNOGEN SITE OF FMD VIRUS, NMR, 10 STRUCTURES (1998) (0)
- peptide analogues, and their uses in particular in pharmaceutical compositions for the diagnosis and (1997) (0)
- De l'Aza-β3Amino Acide aux Peptides Hybrides Immunomodulateurs : Etude Structurale et Evaluation Biologique. (2007) (0)
- Immunogenicity of a liposome-associated synthetic hexapeptide antigen (1991) (0)
- P.298 Diminution des lymphocytes CD4+CD25high (Tregs) circulants au cours de la rectocolite hémorragique (RCH) : comparaison avec la maladie de Crohn colique (MC) (2009) (0)
- Protein microarray characterization of the autoantibody response in systemic lupus erythematosus and related diseases (2001) (0)
- Solution structure of lactam analogue DapD of HIV gp41 600-612 loop (2003) (0)
- LigandContributes to Human Lupus Pathogenesis by Promoting T Follicular Helper Response Graphical (0)
- Comparative analysis of anti-histone and anti-chromatin antibody specificity in lupus erythematosus cell-positive and -negative sera and their relation to disease activity (2001) (0)
- Clinical Significance of Anti-Ubiquitin Antibodies in Systemic Lupus Erythematosus (1989) (0)
- Solution structure of beta3 analogue peptide (HCYS) of HIV gp41 600-612 loop. (2003) (0)
- Active immunization (vaccination) against peptides of IL-1β induces self anti-IL-1β antibodies and protects against collagen-induced arthritis (2005) (0)
- Synthetic peptides vaccines for hiv: the epdope of cbd as an effective immunogen to provide wide neutralizing antibodies against hiv. (2003) (0)
- Solid phase synthesis and immunological properties of cyclic peptides of the hemagglutinin of influenza virus (1990) (0)
- Autophagy pathway as a target of therapeutic P140 peptide used in lupus (2017) (0)
- SOLUTION STRUCTURE OF CGGIRGERG IN CONTACT WITH THE MONOCLONAL ANTIBODY MAB 4X11, NMR, 11 STRUCTURES (1999) (0)
- Autophagy in neuroin fl ammatory diseases (0)
- Early differentiated plasma cells expressing CXCR3 are attracted to inflamed kidneys in lupus (2011) (0)
- [The spliceosome and its interest for lupus therapy]. (2007) (0)
- Retro peptides, antibodies against it, and their uses in diagnosis and vaccination in vitro (1995) (0)
- Peptide analogues as vaccines and immunomodulators (1999) (0)
- Chapter 23 – Histone Autoantibodies (2014) (0)
- Synthetic peptide HIV vaccine: the CBD epitope as an efficient immunogen for the induction of HIV-neutralizing antibodies (2003) (0)
- [Immunogenetics of systemic lupus: adequacy between HLA molecules class II and the germinal genes of antigen receptor of T-lymphocytes favours the production of various antibodies]. (1993) (0)
- [Among the antinuclear antibodies in rheumatoid polyarthritis: antihistone antibodies detected by an immunoenzymatic technic]. (1988) (0)
- The role of lysosomes in metabolic and autoimmune diseases (2023) (0)
- Utilisation de composés dérivés de l'adénine pour le traitement du lupus use of adenine-derived compounds for the treament of lupus (2014) (0)
- Lysosomes as a therapeutic target (2019) (0)
- Presence ofantibodies toubiquitin during theautoimmune response associated withsystemic lupuserythematosus (1988) (0)
- synthetic peptides conjugated ubiquitin and histone H2A (1989) (0)
- [Ubiquitin and degenerative diseases of the central nervous system]. (1992) (0)
- Aberrant macroautophagy and cleaved C3 production in MRL/lpr hippocampus (2019) (0)
- Immunochemical localization oftheC-terminal hexapeptide of histone H3atthesurface ofchromatin subunits (1982) (0)
- Altered expression of glomerular ectonucleotidase in kidney grafts with delayed function. (1996) (0)
- The abscopal effect: Implications for drug discovery in autoimmunity. (2023) (0)
- Chapter 29 SARS-CoV-2, fertility-related autoantibodies and reproductive injury (2023) (0)
- Targeting VEGF-A with a vaccine decreases inflammation and joint destruction in experimental arthritis (2015) (0)
- Chapter 3 Innate immune responses in COVID-19 (2023) (0)
- A2 and B1 in Normal and Lupus Mice Heterogeneous Nuclear Ribonucleoproteins B and T Cell Responses to the Spliceosomal (2000) (0)
- modified peptides and their use to treat autoimmune diseases (2011) (0)
- Solution structure of lactam analogue (DDap) of gp41 600-612 loop of HIV (2003) (0)
- Genetic and environmental factors in Systemic lupus erythematosus (1994) (0)
- Immunogénétique du lupus systémique: l'adéquation entre molécules HLA de classe II et gènes germinaux du récepteur d'antigènes des lymphocytes T favorise la production de certains anticorps. (1993) (0)
- CTL Specific for an Influenza Virus Epitope Pseudopeptide Modulates the Cytokine Profile of A Partially Modified Retro-Inverso (1998) (0)
- Interaction between TCR beta genes and HLA DR-DQ genes determines the response to autoantigen peptides in SLE patients and family members (1993) (0)
- Solution structure of the lactam analogue EDap of HIV gp41 600-612 loop. (2003) (0)
- An Efficient Test Battery for Rapid Screening of Extrapyramidal Side-Effects of Phenothiazine Analogues (2017) (0)
- Aza-peptides and methods of use for the treatment and prevention of immunological disorders. (2006) (0)
- Dendrimers in immunotherapy and hormone therapy in Pharmaceutical applications of dendrimers (2020) (0)
- Multireprésentation of a peptide substrate analogue of DPPIV, including KPR type, in order to inhibit the entry of HIV into cells. (1994) (0)
- New molecules MULTIMERIC, their process for the preparation, and their use for the preparation of drugs (2002) (0)
- the Nonobese Diabetic Mouse T Cell Response to Preproinsulin I and II in (2002) (0)
- Synthetic Peptides an Probes for Autoantibodies (1989) (0)
- Solution structure of synthetic cyclic peptide mimicking the loop of HIV-1 gp41 glycoprotein envelope (2002) (0)
- [Novel strategy in lupus therapy: from the peptide P140 to Lupuzor™]. (2011) (0)
- RETRO-INVERSO ANALOGUE OF THE G-H LOOP OF VP1 IN FOOT-AND-MOUTH-DISEASE (FMD) VIRUS, NMR, 10 STRUCTURES (1999) (0)
- New multimeric molecules, processes for their preparation, and their use for the production of medicines (2003) (0)
- structure of the spliceosomal phosphopeptide P140 (non-phosphorylated form) (2010) (0)
- Design, synthesis and immunogenic properties of a novel class of peptidomimetics (2005) (0)
- Immune response to hn and snRNP in autoimmune mice. A model for the development of lupus autoimmunity by a single initiator T helper epitope? (2001) (0)
- Solution structure of beta3-analogue peptide corresponding to the gp41 600-612 loop of HIV. (2003) (0)
- Anti-dividing cell antigen a novel antinuclear antibody in systemic lupus erythematosus (1989) (0)
- The Role of Post Synthetic Histone Modifications on Chromatin Conformation: an Immunochemical Study (1985) (0)
- Use of compounds derived from adenine to treat lupus (2006) (0)
- Protein microarray characterization of autoantibody responses in rheumatoid arthritis and systemic lupus erythematosus (2002) (0)
- Normal Mice the Immune Response to Preproinsulin in Expression of Preproinsulin-2 Gene Shapes (2003) (0)
- SOLUTION STRUCTURE OF THE ANALOGUE RETRO-INVERSO (mA-R)REGRIGGC IN CONTACT WITH THE MONOCLONAL ANTIBODY MAB 4X11, NMR, 6 STRUCTURES (1999) (0)
- P.300 Expression de l’intégrine β7 par les lymphocytes circulants CD4+, les lymphocytes Tregs (CD4+CD25high) et les lymphocytes CD4+CD25low au cours de la maladie de Crohn (MC) (2009) (0)
- Clinical Connections (2018) (0)
- [Ubiquitinated nuclear proteins and systemic lupus erythematosus]. (1991) (0)
- The pharmacokinetics of ¹²⁴I-rituximab in patients with rheumatoid arthritis. (2011) (0)
- Neuropsychiatric lupus: autophagy and inflammation (2018) (0)
- Mappingofepitopes on U1 snRNPpolypeptide A with synthetic peptides andautoimmune sera (1991) (0)
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