Theodore A. Slotkin

Theodore A. Slotkin's AcademicInfluence.com Rankings

Theodore A. Slotkin

Medical

#951

World Rank

#1225

Historical Rank

Pharmacology

#66

World Rank

#87

Historical Rank

medical Degrees

Theodore A. Slotkin

Philosophy

#3332

World Rank

#5402

Historical Rank

Logic

#1092

World Rank

#1736

Historical Rank

philosophy Degrees

Download Badge

Medical
Philosophy

Theodore A. Slotkin's Degrees

Doctorate Medicine University of Pennsylvania
PhD Pharmacology University of Pennsylvania

Why Is Theodore A. Slotkin Influential?

(Suggest an Edit or Addition)

(See a Problem?)

Theodore A. Slotkin's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Effect of corticosteroids for fetal maturation on perinatal outcomes. NIH Consensus Development Panel on the Effect of Corticosteroids for Fetal Maturation on Perinatal Outcomes. (1995) (1076)
Fetal nicotine or cocaine exposure: which one is worse? (1998) (715)
Cholinergic systems in brain development and disruption by neurotoxicants: nicotine, environmental tobacco smoke, organophosphates. (2004) (521)
The "stress" of being born. (1986) (475)
Is the PentaBDE replacement, tris (1,3-dichloro-2-propyl) phosphate (TDCPP), a developmental neurotoxicant? Studies in PC12 cells. (2011) (320)
Brain anomalies in children exposed prenatally to a common organophosphate pesticide (2012) (314)
Developmental cholinotoxicants: nicotine and chlorpyrifos. (1999) (296)
Developmental neurotoxicity of chlorpyrifos: cellular mechanisms. (1995) (295)
Nicotine and the adolescent brain: insights from an animal model. (2002) (277)
Cellular mechanisms for developmental toxicity of chlorpyrifos: targeting the adenylyl cyclase signaling cascade. (1997) (253)
Role of ornithine decarboxylase and the polyamines in nervous system development: A review (1986) (241)
Adolescent nicotine exposure causes persistent upregulation of nicotinic cholinergic receptors in rat brain regions (1999) (238)
Developmental Exposure of Rats to Chlorpyrifos Leads to Behavioral Alterations in Adulthood, Involving Serotonergic Mechanisms and Resembling Animal Models of Depression (2005) (222)
Persistent behavioral consequences of neonatal chlorpyrifos exposure in rats. (2001) (220)
Prenatal chlorpyrifos exposure in rats causes persistent behavioral alterations. (2002) (219)
Chlorpyrifos exposure during a critical neonatal period elicits gender-selective deficits in the development of coordination skills and locomotor activity. (2000) (219)
Comparative developmental neurotoxicity of organophosphates in vivo: Transcriptional responses of pathways for brain cell development, cell signaling, cytotoxicity and neurotransmitter systems (2007) (208)
Effects of prenatal nicotine exposure on development of central and peripheral cholinergic neurotransmitter systems. Evidence for cholinergic trophic influences in developing brain. (1989) (205)
Adrenomedullary function in the neonatal rat: responses to acute hypoxia. (1985) (205)
If nicotine is a developmental neurotoxicant in animal studies, dare we recommend nicotine replacement therapy in pregnant women and adolescents? (2007) (200)
Comparative Developmental Neurotoxicity of Organophosphate Insecticides: Effects on Brain Development Are Separable from Systemic Toxicity (2006) (196)
An animal model of adolescent nicotine exposure: effects on gene expression and macromolecular constituents in rat brain regions (2000) (195)
Loss of neonatal hypoxia tolerance after prenatal nicotine exposure: Implications for sudden infant death syndrome (1995) (195)
Fetal and adolescent nicotine administration: effects on CNS serotonergic systems (2001) (188)
Developmental neurotoxicity of chlorpyrifos modeled in vitro: comparative effects of metabolites and other cholinesterase inhibitors on DNA synthesis in PC12 and C6 cells. (2001) (186)
Chlorpyrifos Interferes with Cell Development in Rat Brain Regions (1997) (181)
Developmental Neurotoxicity of Perfluorinated Chemicals Modeled in Vitro (2008) (179)
Development of [3H]nicotine binding sites in brain regions of rats exposed to nicotine prenatally via maternal injections or infusions. (1987) (178)
Prenatal nicotine exposure evokes alterations of cell structure in hippocampus and somatosensory cortex. (2002) (177)
Silver Nanoparticles Compromise Neurodevelopment in PC12 Cells: Critical Contributions of Silver Ion, Particle Size, Coating, and Composition (2010) (175)
Prenatal exposure to nicotine impairs nervous system development at a dose which does not affect viability or growth (1989) (171)
Neonatal chlorpyrifos exposure alters synaptic development and neuronal activity in cholinergic and catecholaminergic pathways. (1999) (171)
Modeling the developmental neurotoxicity of chlorpyrifos in vitro: macromolecule synthesis in PC12 cells. (1998) (169)
Silver nanoparticles alter zebrafish development and larval behavior: distinct roles for particle size, coating and composition. (2011) (169)
Effects of prenatal nicotine exposure on biochemical development of rat brain regions: maternal drug infusions via osmotic minipumps. (1987) (167)
Oxidative mechanisms contributing to the developmental neurotoxicity of nicotine and chlorpyrifos. (2005) (166)
Alterations in Central Nervous System Serotonergic and Dopaminergic Synaptic Activity in Adulthood after Prenatal or Neonatal Chlorpyrifos Exposure (2005) (165)
Developmental neurotoxicity of chlorpyrifos in vivo and in vitro: effects on nuclear transcription factors involved in cell replication and differentiation (2000) (164)
Fetal chlorpyrifos exposure: adverse effects on brain cell development and cholinergic biomarkers emerge postnatally and continue into adolescence and adulthood. (2002) (158)
Evaluation of the Association between Maternal Smoking, Childhood Obesity, and Metabolic Disorders: A National Toxicology Program Workshop Review (2012) (154)
Developmental exposure to chlorpyrifos elicits sex-selective alterations of serotonergic synaptic function in adulthood: critical periods and regional selectivity for effects on the serotonin transporter, receptor subtypes, and cell signaling. (2003) (153)
Adolescent vs. adult-onset nicotine self-administration in male rats: duration of effect and differential nicotinic receptor correlates. (2007) (152)
Adrenomedullary catecholamine release in the fetus and newborn: secretory mechanisms and their role in stress and survival. (1988) (151)
Nicotine evokes cell death in embryonic rat brain during neurulation. (1998) (151)
Prenatal exposure to nicotine via maternal infusions: effects on development of catecholamine systems. (1988) (147)
Permanent, Sex-Selective Effects of Prenatal or Adolescent Nicotine Exposure, Separately or Sequentially, in Rat Brain Regions: Indices of Cholinergic and Serotonergic Synaptic Function, Cell Signaling, and Neural Cell Number and Size at 6 Months of Age (2007) (145)
Gender-Specific Effects of Prenatal and Adolescent Exposure to Tobacco Smoke on Auditory and Visual Attention (2007) (144)
Persistent cholinergic presynaptic deficits after neonatal chlorpyrifos exposure (2001) (140)
Adolescent nicotine exposure produces immediate and long-term changes in CNS noradrenergic and dopaminergic function (2001) (139)
Short-Term Adolescent Nicotine Exposure has Immediate and Persistent Effects on Cholinergic Systems: Critical Periods, Patterns of Exposure, Dose Thresholds (2003) (136)
Does early-life exposure to organophosphate insecticides lead to prediabetes and obesity? (2011) (135)
Serotonergic systems targeted by developmental exposure to chlorpyrifos: effects during different critical periods. (2003) (134)
Maternal substance abuse and the developing nervous system (1992) (133)
Developmental neurotoxicity of chlorpyrifos: what is the vulnerable period? (2002) (132)
Behavioral alterations in adolescent and adult rats caused by a brief subtoxic exposure to chlorpyrifos during neurulation. (2004) (131)
Chlorpyrifos elicits mitotic abnormalities and apoptosis in neuroepithelium of cultured rat embryos. (1998) (130)
Persistent and delayed behavioral changes after nicotine treatment in adolescent rats (2000) (128)
Developmental toxicity of nicotine: A transdisciplinary synthesis and implications for emerging tobacco products (2017) (127)
Effects of prenatal nicotine exposure on neuronal development: Selective actions on central and peripheral catecholaminergic pathways (1987) (127)
Functional alterations in CNS catecholamine systems in adolescence and adulthood after neonatal chlorpyrifos exposure. (2002) (127)
Persistent cognitive alterations in rats after early postnatal exposure to low doses of the organophosphate pesticide, diazinon. (2008) (127)
Is oxidative stress involved in the developmental neurotoxicity of chlorpyrifos? (2000) (124)
Developmental neurotoxicity of chlorpyrifos: delayed targeting of DNA synthesis after repeated administration. (1998) (124)
Does the developmental neurotoxicity of chlorpyrifos involve glial targets? Macromolecule synthesis, adenylyl cyclase signaling, nuclear transcription factors, and formation of reactive oxygen in C6 glioma cells (2001) (123)
Role of ornithine decarboxylase in cardiac growth and hypertrophy. (1980) (121)
Screening for Developmental Neurotoxicity Using PC12 Cells: Comparisons of Organophosphates with a Carbamate, an Organochlorine, and Divalent Nickel (2006) (120)
Impaired cardiac function during postnatal hypoxia in rats exposed to nicotine prenatally: implications for perinatal morbidity and mortality, and for sudden infant death syndrome. (1997) (120)
Cholinergic receptors in heart and brainstem of rats exposed to nicotine during development: implications for hypoxia tolerance and perinatal mortality. (1999) (118)
Organophosphate Insecticides Target the Serotonergic System in Developing Rat Brain Regions: Disparate Effects of Diazinon and Parathion at Doses Spanning the Threshold for Cholinesterase Inhibition (2006) (115)
Nicotine is a neurotoxin in the adolescent brain: critical periods, patterns of exposure, regional selectivity, and dose thresholds for macromolecular alterations (2003) (113)
Ornithine decarboxylase as a tool in developmental neurobiology. (1979) (109)
Developmental diazinon neurotoxicity in rats: Later effects on emotional response (2008) (105)
Prenatal Nicotine Exposure Alters the Response to Nicotine Administration in Adolescence: Effects on Cholinergic Systems During Exposure and Withdrawal (2004) (105)
Fetal mechanisms in neurodevelopmental disorders. (2008) (103)
Inhibition of DNA synthesis in neonatal rat brain regions caused by acute nicotine administration. (1991) (103)
Effects of maternal nicotine injections on brain development in the rat: Ornithine decarboxylase activity, nucleic acids and proteins in discrete brain regions (1986) (103)
Developmental Neurotoxicity of Organophosphates: A Case Study of Chlorpyrifos (2006) (102)
Developmental Exposure of Rats to Chlorpyrifos Elicits Sex-Selective Hyperlipidemia and Hyperinsulinemia in Adulthood (2005) (102)
Chapter 34 – Developmental Neurotoxicity of Nicotine (1998) (100)
Chlorpyrifos targets developing glia: effects on glial fibrillary acidic protein. (2002) (99)
Effects of Prenatal Nicotine Exposure on Primate Brain Development and Attempted Amelioration with Supplemental Choline or Vitamin C: Neurotransmitter Receptors, Cell Signaling and Cell Development Biomarkers in Fetal Brain Regions of Rhesus Monkeys (2005) (99)
Marked reduction in the number of platelet-tritiated imipramine binding sites in geriatric depression. (1988) (98)
Glucocorticoids and the development of neuronal function: effects of prenatal dexamethasone exposure on central noradrenergic activity. (1992) (98)
Fetal nicotine exposure ablates the ability of postnatal nicotine challenge to release norepinephrine from rat brain regions. (1992) (98)
Developmental neurotoxicity elicited by prenatal or postnatal chlorpyrifos exposure: effects on neurospecific proteins indicate changing vulnerabilities. (2002) (96)
Oxidative and Excitatory Mechanisms of Developmental Neurotoxicity: Transcriptional Profiles for Chlorpyrifos, Diazinon, Dieldrin, and Divalent Nickel in PC12 Cells (2008) (96)
6 – Prenatal Exposure to Nicotine: What Can We Learn from Animal Models? (1992) (95)
Mode of Action: Disruption of Brain Cell Replication, Second Messenger, and Neurotransmitter Systems During Development Leading to Cognitive Dysfunction—Developmental Neurotoxicity of Nicotine (2005) (94)
Regulatory changes in presynaptic cholinergic function assessed in rapid autopsy material from patients with Alzheimer disease: implications for etiology and therapy. (1990) (94)
Modeling adolescent nicotine exposure: effects on cholinergic systems in rat brain regions (2000) (93)
Prenatal chlorpyrifos exposure elicits presynaptic serotonergic and dopaminergic hyperactivity at adolescence: critical periods for regional and sex-selective effects. (2007) (92)
Exposure to Organophosphates Reduces the Expression of Neurotrophic Factors in Neonatal Rat Brain Regions: Similarities and Differences in the Effects of Chlorpyrifos and Diazinon on the Fibroblast Growth Factor Superfamily (2007) (92)
Ontogeny of adrenomedullary responses to hypoxia and hypoglycemia: Role of splanchnic innervation (1986) (90)
Programming of brainstem serotonin transporter development by prenatal glucocorticoids. (1996) (90)
Deficits in development of central cholinergic pathways caused by fetal nicotine exposure: differential effects on choline acetyltransferase activity and [3H]hemicholinium-3 binding. (1992) (89)
Early Biochemical Detection of Delayed Neurotoxicity Resulting from Developmental Exposure to Chlorpyrifos (1998) (89)
Guidelines for developmental neurotoxicity and their impact on organophosphate pesticides: a personal view from an academic perspective. (2004) (89)
Nonenzymatic Functions of Acetylcholinesterase Splice Variants in the Developmental Neurotoxicity of Organophosphates: Chlorpyrifos, Chlorpyrifos Oxon, and Diazinon (2006) (87)
Control of nucleic acid and protein synthesis in developing brain, kidney, and heart of the neonatal rat: effects of alpha-difluoromethylornithine, a specific, irreversible inhibitor of ornithine decarboxylase. (1984) (87)
Persistent behavioral alterations in rats neonatally exposed to low doses of the organophosphate pesticide, parathion (2008) (86)
Maturation of sympathetic neurotransmission in the rat heart. VIII. Slowed development of noradrenergic synapses resulting from hypothyroidism. (1981) (86)
Exposure of Neonatal Rats to Parathion Elicits Sex-Selective Reprogramming of Metabolism and Alters the Response to a High-Fat Diet in Adulthood (2008) (86)
Development of sympathetic ganglionic neurotransmission in the neonatal rat. Pre- and postganglionic nerve response to asphyxia and 2-deoxyglucose (1982) (86)
Chlorpyrifos Affects Phenotypic Outcomes in a Model of Mammalian Neurodevelopment: Critical Stages Targeting Differentiation in PC12 Cells (2005) (85)
Ornithine decarboxylase and polyamines in tissues of the neonatal rat: effects of alpha-difluoromethylornithine, a specific, irreversible inhibitor of ornithine decarboxylase. (1982) (85)
Silver exposure in developing zebrafish (Danio rerio): persistent effects on larval behavior and survival. (2010) (84)
Prenatal Nicotine Exposure Alters the Responses to Subsequent Nicotine Administration and Withdrawal in Adolescence: Serotonin Receptors and Cell Signaling (2006) (84)
The alterations in CNS serotonergic mechanisms caused by neonatal chlorpyrifos exposure are permanent. (2005) (83)
Critical Prenatal and Postnatal Periods for Persistent Effects of Dexamethasone on Serotonergic and Dopaminergic Systems (2006) (83)
Visuospatial Memory Deficits Emerging During Nicotine Withdrawal in Adolescents with Prenatal Exposure to Active Maternal Smoking (2006) (83)
Neonatal Exposure to Low Doses of Diazinon: Long-Term Effects on Neural Cell Development and Acetylcholine Systems (2007) (83)
Critical periods for the role of oxidative stress in the developmental neurotoxicity of chlorpyrifos and terbutaline, alone or in combination. (2005) (82)
Chlorpyrifos exposure during neurulation: cholinergic synaptic dysfunction and cellular alterations in brain regions at adolescence and adulthood. (2004) (82)
Prenatal nicotine exposure impairs β-adrenergic function: Persistent chronotropic subsensitivity despite recovery from deficits in receptor binding (1990) (81)
Increased nicotine self-administration following prenatal exposure in female rats (2006) (80)
Developmental neurotoxicants target neurodifferentiation into the serotonin phenotype: Chlorpyrifos, diazinon, dieldrin and divalent nickel. (2008) (80)
Quantitative morphological assessment reveals neuronal and glial deficits in hippocampus after a brief subtoxic exposure to chlorpyrifos in neonatal rats. (2005) (80)
Neuroinflammation and Behavioral Abnormalities after Neonatal Terbutaline Treatment in Rats: Implications for Autism (2007) (79)
Perinatal exposure to environmental tobacco smoke upregulates nicotinic cholinergic receptors in monkey brain. (2002) (79)
Beta adrenergic control of macromolecule synthesis in neonatal rat heart, kidney and lung: relationship to sympathetic neuronal development. (1987) (79)
Developmental neurotoxicity of low dose diazinon exposure of neonatal rats: Effects on serotonin systems in adolescence and adulthood (2008) (77)
β-adrenoceptor signaling and its control of cell replication in MDA-MB-231 human breast cancer cells (2000) (76)
Ontogenesis of β-Adrenoceptor Signaling: Implications for Perinatal Physiology and for Fetal Effects of Tocolytic Drugs (2003) (76)
Adolescent nicotine administration alters serotonin receptors and cell signaling mediated through adenylyl cyclase (2002) (76)
Cryptic brain cell injury caused by fetal nicotine exposure is associated with persistent elevations of c-fos protooncogene expression 1 Supported by a grant from the Smokeles Tobacco Research Council. 1 (1997) (76)
Impact of fetal nicotine exposure on development of rat brain regions: Critical sensitive periods or effects of withdrawal? (1993) (76)
Differential development of cholinergic nerve terminal markers in rat brain regions: implications for nerve terminal density, impulse activity and specific gene expression (1993) (75)
Fetal cocaine exposure causes persistent noradrenergic hyperactivity in rat brain regions: effects on neurotransmitter turnover and receptors. (1992) (75)
Targeting of neurotrophic factors, their receptors, and signaling pathways in the developmental neurotoxicity of organophosphates in vivo and in vitro (2008) (73)
Silver Impairs Neurodevelopment: Studies in PC12 Cells (2009) (72)
Critical Review (2007) (72)
Release of corticotropin-releasing factor from rat brain regions in vitro. (1986) (71)
Cocaine acutely inhibits DNA synthesis in developing rat brain regions: evidence for direct actions (1990) (71)
Overexpression of the high affinity choline transporter in cortical regions affected by Alzheimer's disease. Evidence from rapid autopsy studies. (1994) (70)
The use of pharmacotherapies for smoking cessation during pregnancy (2000) (68)
Oxidative stress from diverse developmental neurotoxicants: antioxidants protect against lipid peroxidation without preventing cell loss. (2010) (67)
Effects of α-difluoromethylornithine, a specific irreversible inhibitor of ornithine decarboxylase, on nucleic acids and proteins in developing rat brain: Critical perinatal periods for regional selectivity (1986) (67)
Does Prenatal Nicotine Exposure Sensitize the Brain to Nicotine-Induced Neurotoxicity in Adolescence? (2004) (65)
Modeling geriatric depression in animals: biochemical and behavioral effects of olfactory bulbectomy in young versus aged rats. (1999) (64)
Accelerated development of rat sympathetic neurotransmission caused by neonatal triiodothyronine administration. (1979) (64)
Nicotine is a developmental neurotoxicant and neuroprotectant: stage-selective inhibition of DNA synthesis coincident with shielding from effects of chlorpyrifos. (2003) (64)
Beta-2 adrenergic control of ornithine decarboxylase activity in brain regions of the developing rat. (1985) (64)
Terbutaline Is a Developmental Neurotoxicant: Effects on Neuroproteins and Morphology in Cerebellum, Hippocampus, and Somatosensory Cortex (2004) (63)
Impaired development of cerebellar cortex in rats treated postnatally with α-difluorometh ylornithine (1985) (63)
Prenatal stress elicits regionally selective changes in basal FGF-2 gene expression in adulthood and alters the adult response to acute or chronic stress (2005) (62)
Effects of acute hypoxia on neonatal rat brain: Regionally selective, long-term alterations in catecholamine levels and turnover (1990) (62)
Ameliorating the Developmental Neurotoxicity of Chlorpyrifos: A Mechanisms-Based Approach in PC12 Cells (2007) (62)
Perinatal Environmental Tobacco Smoke Exposure in Rhesus Monkeys: Critical Periods and Regional Selectivity for Effects on Brain Cell Development and Lipid Peroxidation (2005) (62)
Lasting Effects of Developmental Dexamethasone Treatment on Neural Cell Number and Size, Synaptic Activity, and Cell Signaling: Critical Periods of Vulnerability, Dose–Effect Relationships, Regional Targets, and Sex Selectivity (2006) (62)
Perinatal methadone addiction affects brain synaptic development of biogenic amine systems in the rat. (1979) (62)
Developmental exposure to terbutaline and chlorpyrifos: pharmacotherapy of preterm labor and an environmental neurotoxicant converge on serotonergic systems in neonatal rat brain regions. (2005) (61)
Fetal dexamethasone exposure interferes with establishment of cardiac noradrenergic innervation and sympathetic activity. (1993) (61)
Serotonin transporter expression in rat brain regions and blood platelets: Aging and glucocorticoid effects (1997) (61)
Fetal dexamethasone exposure alters macromolecular characteristics of rat brain development: a critical period for regionally selective alterations? (1992) (60)
Morphologic effects of subtoxic neonatal chlorpyrifos exposure in developing rat brain: regionally selective alterations in neurons and glia. (2004) (60)
Developmental effects of chlorpyrifos extend beyond neurotoxicity: critical periods for immediate and delayed-onset effects on cardiac and hepatic cell signaling. (2004) (60)
Postnatal development of brain alpha1-adrenergic receptors: In vitro autoradiography with [125i]HEAT in normal rats and rats treated with alpha-difluoromethylornithine, a specific, irreversible inhibitor of ornithine decarboxylase (1985) (60)
Early postnatal parathion exposure in rats causes sex-selective cognitive impairment and neurotransmitter defects which emerge in aging (2010) (60)
Responses of heart ornithine decarboxylase and adrenal catecholamines to methadone and sympathetic stimulants in developing and adults rats. (1978) (60)
Glucocorticoid administration alters nuclear transcription factors in fetal rat brain: implications for the use of antenatal steroids. (1998) (60)
Cell Signaling as a Target and Underlying Mechanism for Neurobehavioral Teratogenesis (2002) (59)
Biochemical Determinants of Growth Sparing during Neonatal Nutritional Deprivation or Enhancement: Ornithine Decarboxylase, Polyamines, and Macromolecules in Brain Regions and Heart (1987) (58)
Beta-adrenergic receptor overexpression in the fetal rat: distribution, receptor subtypes, and coupling to adenylate cyclase activity via G-proteins. (1994) (58)
Critical periods for chlorpyrifos-induced developmental neurotoxicity: alterations in adenylyl cyclase signaling in adult rat brain regions after gestational or neonatal exposure. (2003) (58)
Ornithine decarboxylase: marker of neuroendocrine and neurotransmitter actions. (1983) (58)
Development of central control of norepinephrine turnover and release in the rat heart: Responses to tyramine, 2-Deoxyglucose and Hydralazine (1981) (58)
Alterations in serotonin transporter expression in brain regions of rats exposed neonatally to chlorpyrifos. (2001) (56)
Prenatal nicotine exposure in rhesus monkeys compromises development of brainstem and cardiac monoamine pathways involved in perinatal adaptation and sudden infant death syndrome: amelioration by vitamin C. (2011) (56)
Is fipronil safer than chlorpyrifos? Comparative developmental neurotoxicity modeled in PC12 cells (2009) (56)
CONCOMITANT DEVELOPMENT OF [3H]‐DOPAMINE AND [3H]‐5‐HYDROXYTRYPTAMINE UPTAKE SYSTEMS IN RAT BRAIN REGIONS (1979) (56)
An invertebrate model of the developmental neurotoxicity of insecticides: effects of chlorpyrifos and dieldrin in sea urchin embryos and larvae. (2001) (56)
Effects of maternal methadone administration on ornithine decarboxylase in brain and heart of the offspring: relationships of enzyme activity to dose and to growth impairment in the rat. (1980) (56)
Developmental neurotoxicity of parathion: progressive effects on serotonergic systems in adolescence and adulthood. (2009) (55)
Regulation of rat heart ornithine decarboxylase: change in affinity for ornithine evoked by neuronal, hormonal, and ontogenetic stimuli. (1979) (55)
Neurobehavioral damage to cholinergic systems caused by prenatal exposure to heroin or phenobarbital: cellular mechanisms and the reversal of deficits by neural grafts. (2000) (55)
Neonatal chlorpyrifos exposure targets multiple proteins governing the hepatic adenylyl cyclase signaling cascade: implications for neurotoxicity. (2000) (53)
Blood levels and urinary excretion of harmine and its metabolites in man and rats. (1970) (53)
RAT BRAIN SYNAPTIC VESICLES: UPTAKE SPECIFICITIES OF [3H]NOREPINEPHRINE AND [3H]SEROTONIN IN PREPARATIONS FROM WHOLE BRAIN AND BRAIN REGIONS 1 (1978) (53)
Transcriptional biomarkers distinguish between vulnerable periods for developmental neurotoxicity of chlorpyrifos: Implications for toxicogenomics (2003) (53)
Developmental neurotoxicity of organophosphates targets cell cycle and apoptosis, revealed by transcriptional profiles in vivo and in vitro. (2012) (53)
Promotional role for glucocorticoids in the development of intracellular signalling: enhanced cardiac and renal adenylate cyclase reactivity to beta-adrenergic and non-adrenergic stimuli after low-dose fetal dexamethasone exposure. (1992) (52)
Protein kinase C is a target for diverse developmental neurotoxicants: Transcriptional responses to chlorpyrifos, diazinon, dieldrin and divalent nickel in PC12 cells (2009) (52)
Impact of adolescent nicotine exposure on adenylyl cyclase-mediated cell signaling: enzyme induction, neurotransmitter-specific effects, regional selectivities, and the role of withdrawal (2003) (52)
Uptake of (-) 3H-norepinephrine by storage vesicles prepared from whole rat brain: properties of the uptake system and its inhibition by drugs. (1977) (52)
Control of adenylate cyclase activity in developing rat heart and liver: effects of prenatal exposure to terbutaline or dexamethasone. (1991) (52)
Undernutrition and Overnutrition in the Neonatal Rat: Long-Term Effects on Noradrenergic Pathways in Brain Regions (1990) (52)
Effects of neonatal or maternal methadone administration on ornithine decarboxylase activity in brain and heart of developing rats. (1976) (51)
Ontogeny of cardiac beta-adrenoceptor desensitization mechanisms: agonist treatment enhances receptor/G-protein transduction rather than eliciting uncoupling. (1999) (51)
Fetal dexamethasone exposure impairs cellular development in neonatal rat heart and kidney: effects on DNA and protein in whole tissues. (1991) (50)
Effect of maternal ethanol ingestion on neonatal rat brain and heart ornithine decarboxylase. (1977) (50)
Alterations of serotonin synaptic proteins in brain regions of neonatal Rhesus monkeys exposed to perinatal environmental tobacco smoke (2006) (50)
Maturation of sympathetic neurotransmission in the rat heart. V. Development of baroreceptor control of sympathetic tone. (1980) (50)
Fetal nicotine exposure produces postnatal up-regulation of adenylate cyclase activity in peripheral tissues. (1990) (50)
Developmental neurotoxicity of chlorpyrifos: targeting glial cells. (2005) (49)
Effects of neonatal hypoxia on brain development in the rat: immediate and long-term biochemical alterations in discrete regions (1986) (48)
α7 Nicotinic acetylcholine receptors targeted by cholinergic developmental neurotoxicants: nicotine and chlorpyrifos (2004) (48)
Beta-adrenoceptor signaling in the developing brain: sensitization or desensitization in response to terbutaline. (2001) (48)
Ontogeny of regulatory mechanisms for beta-adrenoceptor control of rat cardiac adenylyl cyclase: targeting of G-proteins and the cyclase catalytic subunit. (1997) (48)
Development of the Sympathoadrenal Axis (1986) (48)
Does pharmacotherapy for preterm labor sensitize the developing brain to environmental neurotoxicants? Cellular and synaptic effects of sequential exposure to terbutaline and chlorpyrifos in neonatal rats. (2004) (47)
Adrenergic control of DNA synthesis in developing rat brain regions: Effects of intracisternal administration of isoproterenol (1988) (47)
Maturation of the adrenal medulla. II. Content and properties of catecholamine storage vesicles of the rat. (1973) (47)
Endocrine Control of Synaptic Development in the Sympathetic Nervous System: The Cardiac-Sympathetic Axis (1986) (47)
Agonist-induced sensitization of beta-adrenoceptor signaling in neonatal rat heart: expression and catalytic activity of adenylyl cyclase. (1999) (46)
Lasting effects of nicotine treatment and withdrawal on serotonergic systems and cell signaling in rat brain regions: Separate or sequential exposure during fetal development and adulthood (2007) (46)
Effect of Maternal Smoking on Fetal Catecholamine Concentrations at Birth (2003) (46)
Fetal nicotine exposure alters ontogeny of M1-receptors and their link to G-proteins. (1993) (46)
Ornithine decarboxylase in developing rat heart and brain: role of sympathetic development for responses to autonomic stimulants and the effects of reserpine on maturation. (1977) (46)
Maturation of sympathetic neurotransmission in the rat heart. IX. Development of transsynaptic regulation of cardiac adrenergic sensitivity. (1982) (46)
Cognitive and Behavioral Impairments Evoked by Low-Level Exposure to Tobacco Smoke Components: Comparison with Nicotine Alone. (2016) (46)
Neural grafting reverses prenatal drug-induced alterations in hippocampal PKC and related behavioral deficits. (2000) (45)
Expression of mRNA coding for the serotonin transporter in aged vs. young rat brain: differential effects of glucocorticoids (1996) (45)
Effects of postnatal reserpine administration on sympatho-adrenal development in the rat. (1976) (45)
Maturation of sympathetic neurotransmission in the rat heart. II. Enhanced development of presynaptic and postsynaptic components of noradrenergic synapses as a result of neonatal hyperthyroidism. (1980) (45)
Developmental neurotoxicity elicited by gestational exposure to chlorpyrifos: when is adenylyl cyclase a target? (2003) (45)
Uptake, storage, and distribution of amines in bovine adrenal medullary vesicles. (1971) (45)
Silver exposure in developing zebrafish produces persistent synaptic and behavioral changes. (2011) (45)
Obligatory role of thyroid hormones in development of peripheral sympathetic and central nervous system catecholaminergic neurons: effects of propylthiouracil-induced hypothyroidism on transmitter levels, turnover and release. (1984) (44)
Development of polyamine and biogenic amine systems in brains and hearts of neonatal rats given dexamethasone: role of biochemical alterations in cellular maturation for producing deficits in ontogeny of neurotransmitter levels, uptake, storage and turnover. (1982) (44)
Maturation of the adrenal medulla--IV. Effects of morphine. (1975) (44)
Developmental exposure to terbutaline alters cell signaling in mature rat brain regions and augments the effects of subsequent neonatal exposure to the organophosphorus insecticide chlorpyrifos. (2005) (44)
Chlorpyrifos releases norepinephrine from adult and neonatal rat brain synaptosomes. (1999) (44)
Neonatal Organophosphorus Pesticide Exposure Alters the Developmental Trajectory of Cell-Signaling Cascades Controlling Metabolism: Differential Effects of Diazinon and Parathion (2009) (43)
All-or-none secretion of adrenal medullary storage vesicle contents in the rat. (1973) (43)
Beta-adrenoceptor signaling and its control of cell replication in MDA-MB-231 human breast cancer cells. (2000) (43)
Catecholamine content of the carotid body in cats ventilated with 8 - 40% oxygen. (1975) (43)
Developmental Neurotoxicity of Tobacco Smoke Directed Toward Cholinergic and Serotonergic Systems: More Than Just Nicotine. (2015) (43)
Stimulation of ornithine decarboxylase by histamine or norepinephrine in brain regions of the developing rat: evidence for biogenic amines as trophic agents in neonatal brain development. (1983) (43)
Neonatal exposure to parathion alters lipid metabolism in adulthood: Interactions with dietary fat intake and implications for neurodevelopmental deficits (2010) (43)
Dual control of DNA synthesis by α- and β-adrenergic mechanisms in normoxic and hypoxic neonatal rat brain (1990) (43)
Do sympathetic neurons coordinate cellular development in the heart and kidney? Effects of neonatal central and peripheral catecholaminergic lesions on cardiac and renal nucleic acids and proteins. (1988) (43)
Altered development of basal and forskolin-stimulated adenylate cyclase activity in brain regions of rats exposed to nicotine prenatally. (1992) (43)
Prenatal Dexamethasone Exposure Causes Loss of Neonatal Hypoxia Tolerance: Cellular Mechanisms (1994) (42)
Role of polyamines in isoproterenol-induced cardiac hypertrophy: effects of alpha-difluoromethylornithine, an irreversible inhibitor of ornithine decarboxylase. (1982) (42)
Developmental toxicity of terbutaline: Critical periods for sex-selective effects on macromolecules and DNA synthesis in rat brain, heart, and liver (2003) (41)
Glucocorticoids enhance intracellular signaling via adenylate cyclase at three distinct loci in the fetus: a mechanism for heterologous teratogenic sensitization? (1994) (41)
Neonatal methylmercury poisoning in the rat: effects on development of central catecholamine neurotransmitter systems. (1982) (41)
Cocaine inhibits central noradrenergic and dopaminergic activity during the critical developmental period in which catecholamines influence cell development. (1995) (41)
Neurobehavioral teratogenicity of perfluorinated alkyls in an avian model. (2010) (41)
Effects of maternal ethanol ingestion on amine uptake into synaptosomes of fetal and neonatal rat brain. (1977) (41)
Role of carotid body catecholamines in chemoreceptor function (1978) (40)
Regulation of adrenal chromaffin cell development by the central monoaminergic system: Differential control of norepinephrine and epinephrine levels and secretory responses (1987) (40)
Transcriptional profiles reveal similarities and differences in the effects of developmental neurotoxicants on differentiation into neurotransmitter phenotypes in PC12 cells (2009) (40)
Developmental exposure to terbutaline and chlorpyrifos, separately or sequentially, elicits presynaptic serotonergic hyperactivity in juvenile and adolescent rats (2007) (40)
Separate or sequential exposure to nicotine prenatally and in adulthood: Persistent effects on acetylcholine systems in rat brain regions (2007) (39)
Regulation of fetal cardiac and hepatic beta-adrenoceptors and adenylyl cyclase signaling: terbutaline effects. (2001) (39)
Pituitary-thyroid axis reactivity to hyper- and hypothyroidism in the perinatal period: ontogeny of regulation of regulation and long-term programming of responses. (1992) (39)
Neonatal chlorpyrifos administration elicits deficits in immune function in adulthood: a neural effect? (2001) (38)
Branched-chain amino acids alter neurobehavioral function in rats. (2013) (38)
Adolescent nicotine treatment changes the response of acetylcholine systems to subsequent nicotine administration in adulthood (2008) (38)
Exposure to methylmercury in utero: effects on biochemical development of catecholamine neurotransmitter systems. (1984) (38)
Impaired development of central and peripheral catecholamine neurotransmitter systems in preweanling rats treated with alpha-difluoromethylornithine, a specific irreversible inhibitor of ornithine decarboxylase. (1982) (38)
Maturation of the adrenal medulla. I. Uptake and storage of amines in isolated storage vesicles of the rat. (1973) (37)
Gestational Dexamethasone Treatment Elicits Sex-Dependent Alterations in Locomotor Activity, Reward-Based Memory and Hippocampal Cholinergic Function in Adolescent and Adult Rats (2005) (37)
3H-Dopamine uptake by synaptic storage vesicles of rat whole brain and brain regions. (1978) (37)
Disruption of Rat Forebrain Development by Glucocorticoids: Critical Perinatal Periods for Effects on Neural Cell Acquisition and on Cell Signaling Cascades Mediating Noradrenergic and Cholinergic Neurotransmitter/Neurotrophic Responses (2005) (37)
Perinatal exposure to environmental tobacco smoke induces adenylyl cyclase and alters receptor-mediated cell signaling in brain and heart of neonatal rats (2001) (37)
DEVELOPMENT OF NICOTINIC RESPONSES IN THE RAT ADRENAL MEDULLA AND LONG‐TERM EFFECTS OF NEONATAL NICOTINE ADMINISTRATION (1977) (37)
Ontogeny of Histaminergic Neurotransmission in the Rat Brain: Concomitant Development of Neuronal Histamine, H‐1 Receptors, and H‐1 Receptor‐Mediated Stimulation of Phospholipid Turnover (1981) (36)
Thyroid hormone differentially regulates development of beta-adrenergic receptors, adenylate cyclase and ornithine decarboxylase in rat heart and kidney. (1991) (36)
Glucocorticoids regulate the ontogenetic transition of adrenergic receptor subtypes in rat liver. (1991) (36)
Administration of nicotine to adolescent rats evokes regionally selective upregulation of CNS α7 nicotinic acetylcholine receptors (2004) (36)
Exposure of Developing Chicks to Perfluorooctanoic Acid Induces Defects in Prehatch and Early Posthatch Development (2008) (36)
Developmental neurotoxic effects of chlorpyrifos on acetylcholine and serotonin pathways in an avian model. (2008) (36)
β-adrenoceptor control of cardiac adenylyl cyclase during development: agonist pretreatment in the neonate uniquely causes heterologous sensitization, not desensitization (1995) (35)
beta-Adrenergic modulation of muscarinic cholinergic receptor expression and function in developing heart. (2002) (35)
Serotonergic Cell Signaling in an Animal Model of Aging and Depression: Olfactory Bulbectomy Elicits Different Adaptations in Brain Regions of Young Adult vs Aging Rats (2005) (35)
Effects of reserpine on the content and properties of rat adrenal medullary storage vesicles. (1973) (35)
Fetal terbutaline exposure causes selective postnatal increases in cerebellar alpha-adrenergic receptor binding. (1990) (35)
The sea urchin embryo as a model for mammalian developmental neurotoxicity: ontogenesis of the high-affinity choline transporter and its role in cholinergic trophic activity. (2003) (35)
Maturation of sympathetic neurotransmission in the rat heart. I. Ontogeny of the synaptic vesicle uptake mechanism and correlation with development of synaptic function. Effects of neonatal methadone administration on development of synaptic vesicles. (1980) (34)
Effects of morphine on the rat adrenal medulla. (1975) (34)
Brominated and organophosphate flame retardants target different neurodevelopmental stages, characterized with embryonic neural stem cells and neuronotypic PC12 cells. (2017) (34)
Effects of aging and glucocorticoid treatment on monoamine oxidase subtypes in rat cerebral cortex: Therapeutic implications (1998) (34)
Effects of prenatal reserpine administration on development of the rat adrenal medulla and central nervous system. (1976) (34)
The sea urchin embryo, an invertebrate model for mammalian developmental neurotoxicity, reveals multiple neurotransmitter mechanisms for effects of chlorpyrifos: Therapeutic interventions and a comparison with the monoamine depleter, reserpine (2007) (34)
Cardiac alpha-adrenergic receptor expression is regulated by thyroid hormone during a critical developmental period. (1996) (34)
Prenatal terbutaline exposure in the rat: Selective effects on development of noradrenergic projections to cerebellum (1989) (34)
Nicotine Therapy in Adulthood Reverses the Synaptic and Behavioral Deficits Elicited by Prenatal Exposure to Phenobarbital (2005) (33)
Cholinergic synaptic signaling mechanisms underlying behavioral teratogenicity: Effects of nicotine, chlorpyrifos, and heroin converge on protein kinase C translocation in the intermedial part of the hyperstriatum ventrale and on imprinting behavior in an avian model (2004) (33)
Sex-selective hippocampal alterations after adolescent nicotine administration: effects on neurospecific proteins. (2003) (33)
Development of adrenergic receptor binding sites in brain regions of the neonatal rat: effects of prenatal or postnatal exposure to methylmercury. (1987) (33)
Alterations in PKCgamma in the mouse hippocampus after prenatal exposure to heroin: a link from cell signaling to behavioral outcome. (2003) (33)
Phosphatidic acid phosphatase in neonatal rat lung: effects of prenatal dexamethasone or terbutaline treatment on basal activity and on responsiveness to beta adrenergic stimulation. (1989) (33)
Non-neurogenic mechanism for reserpine-induced release of catecholamines from the adrenal medulla of neonatal rats: Possible modulation by opiate receptors (1982) (33)
Persistent c-fos Induction by Nicotine in Developing Rat Brain Regions: Interaction with Hypoxia (1999) (32)
Histamine stimulates brain phospholipid turnover through a direct, H-1 receptor-mediated mechanism. (1980) (32)
Critical periods for the role of ornithine decarboxylase and the polyamines in growth and development of the rat: Effects of exposure to α-difluoromethylornithine during discrete prenatal or postnatal intervals (1983) (32)
Recovery of rat adrenal amine stores after insulin administration. (1973) (31)
Hypothetical model of catecholamine uptake into adrenal medullary storage vesicles (1973) (31)
Convergent Effects on Cell Signaling Mechanisms Mediate the Actions of Different Neurobehavioral Teratogens: Alterations in Cholinergic Regulation of Protein Kinase C in Chick and Avian Models (2004) (31)
Maturation of sympathetic neurotransmission in the rat heart. VII. Suppression of sympathetic responses by dexamethasone. (1981) (31)
Does thyroid disruption contribute to the developmental neurotoxicity of chlorpyrifos? (2013) (31)
Adverse Neurodevelopmental Effects of Dexamethasone Modeled in PC12 Cells: Identifying the Critical Stages and Concentration Thresholds for the Targeting of Cell Acquisition, Differentiation and Viability (2006) (31)
In vitro models reveal differences in the developmental neurotoxicity of an environmental polycylic aromatic hydrocarbon mixture compared to benzo[a]pyrene: Neuronotypic PC12 Cells and embryonic neural stem cells. (2017) (31)
Thyroid hormone regulates ontogeny of beta adrenergic receptors and adenylate cyclase in rat heart and kidney: effects of propylthiouracil-induced perinatal hypothyroidism. (1992) (31)
Fetal dexamethasone exposure accelerates development of renal function: relationship to dose, cell differentiation and growth inhibition. (1992) (30)
A unique role for striatal serotonergic systems in the withdrawal from adolescent nicotine administration. (2007) (30)
Does concurrent or prior nicotine exposure interact with neonatal hypoxia to produce cardiac cell damage? (1995) (30)
The role of neural input in the effects of morphine on the rat adrenal medulla. (1976) (30)
Thyroid hormone differentially regulates cellular development in neonatal rat heart and kidney. (1992) (29)
Prenatal dexamethasone administration disrupts the pattern of cellular development in rat lung. (1989) (29)
Do glucocorticoids contribute to the abnormalities in serotonin transporter expression and function seen in depression? An animal model (1996) (29)
Development of brain beta-adrenergic receptors after neonatal 6-Hydroxydopamine treatment (1988) (28)
Cellular determinants of reduced adaptability of the aging brain: neurotransmitter utilization and cell signaling responses after MDMA lesions (2000) (28)
Development of central and peripheral catecholaminergic systems in rats addicted perinatally to methadone (1977) (28)
Exposure of Neonatal Rats to Parathion Elicits Sex-Selective Impairment of Acetylcholine Systems in Brain Regions during Adolescence and Adulthood (2008) (28)
Modeling the developmental neurotoxicity of nicotine in vitro: cell acquisition, growth and viability in PC12 cells. (2005) (28)
Chronic prenatal nicotine exposure sensitizes rat brain to acute postnatal nicotine challenge as assessed with ornithine decarboxylase. (1991) (28)
Consumption of a High-Fat Diet in Adulthood Ameliorates the Effects of Neonatal Parathion Exposure on Acetylcholine Systems in Rat Brain Regions (2009) (28)
Non-neurogenic adrenal catecholamine release in the neonatal rat: exocytosis or diffusion? (1986) (27)
Urinary metabolities of harmine in the rat and their inhibition of monoamine oxidase. (1970) (27)
Maturation of the adrenal medulla. III. Practical and theoretical considerations of age-dependent alterations in kinetics of incorporation of catecholamines and non-catecholamines. (1975) (27)
Benzo[a]pyrene impairs neurodifferentiation in PC12 cells (2009) (27)
Regulation of ornithine decarboxylase activity in the developing heart of euthyroid or hyperthyroid rats. (1980) (27)
In search of a mechanism for receptor-mediated neurobehavioral teratogenesis by nicotine: catecholamine release by nicotine in immature rat brain regions. (1994) (27)
Maturation of sympathetic neurotransmission in the efferent pathway to the rat heart: Ultrastructural analysis of ganglionic synaptogenesis in euthyroid and hyperthyroid neonates (1981) (27)
Role of presynaptic input in the ontogeny of adrenergic cell signaling in rat brain: beta receptors, adenylate cyclase and c-fos protooncogene expression. (1995) (27)
Mimicking maternal smoking and pharmacotherapy of preterm labor: Interactions of fetal nicotine and dexamethasone on serotonin and dopamine synaptic function in adolescence and adulthood (2010) (27)
Ischemia contributes to adverse effects of cocaine on brain development: Suppression of ornithine decarboxylase activity in neonatal rat (1991) (27)
Acute and chronic effects of nicotine on synthesis and storage of catecholamines in the rat adrenal medulla. (1975) (26)
Compartmental analysis of amine storage in bovine adrenal medullary granules. (1971) (26)
Septohippocampal cholinergic changes after destruction of the A10-septal dopaminergic pathways (1993) (26)
Diverse neurotoxicants converge on gene expression for neuropeptides and their receptors in an in vitro model of neurodifferentiation: Effects of chlorpyrifos, diazinon, dieldrin and divalent nickel in PC12 cells (2010) (26)
Effects of Prenatal Dexamethasone on Development of Ornithine Decarboxylase Activity in Brain and Peripheral Tissues of Rats (1988) (26)
Beta-adrenergic control of c-fos expression in fetal and neonatal rat tissues: relationship to cell differentiation and teratogenesis. (1995) (26)
Diverse neurotoxicants target the differentiation of embryonic neural stem cells into neuronal and glial phenotypes. (2016) (26)
Beta-adrenoceptor-mediated cell signaling in the neonatal heart and liver: responses to terbutaline. (2001) (25)
Biochemical mechanisms of developmental neurotoxicity of methylmercury. (1987) (25)
Delays in growth and biochemical development of rat brain caused by maternal methadone administration: are the alterations in synaptogenesis and cellular maturation independent of reduced maternal food intake? (1982) (25)
Role of sympathetic neurons in development of beta-adrenergic control of ornithine decarboxylase activity in peripheral tissues: effects of neonatal 6-hydroxydopamine treatment. (1989) (25)
Effects of fetal nicotine exposure on development of adrenergic receptor binding in rat brain regions: selective changes in a1-receptors (1989) (25)
Organ specificity of neonatal methyl mercury hydroxide poisoning in the rat: effects of ornithine decarboxylase activity in developing tissues. (1982) (24)
Ontogeny of (−)-[3H]norepinephrine uptake properties of synaptic storage vesicles of rat brain (1978) (24)
Role of ornithine decarboxylase and the polyamines in nervous system development: Short-term postnatal administration of α-difluoromethylornithine, an irreversible inhibitor of ornithine decarboxylase (1983) (23)
Neural input and the development of adrenergic intracellular signaling: neonatal denervation evokes neither receptor upregulation nor persistent supersensitivity of adenylate cyclase. (1995) (23)
Disparate developmental neurotoxicants converge on the cyclic AMP signaling cascade, revealed by transcriptional profiles in vitro and in vivo (2010) (23)
Dose-dependent glucocorticoid effects on noradrenergic synaptogenesis in rat brain: ontogeny of [3H]desmethylimipramine binding sites after fetal exposure to dexamethasone. (1991) (23)
Developmental exposure to organophosphates triggers transcriptional changes in genes associated with Parkinson's disease in vitro and in vivo (2011) (23)
Effects of neonatal methylmercury exposure on adrenergic receptor binding sites in peripheral tissues of the developing rat. (1986) (23)
Perinatal dietary supplementation with a commercial soy lecithin preparation: effects on behavior and brain biochemistry in the developing rat. (1985) (22)
Development of the linkage of beta-adrenergic receptors to cardiac hypertrophy and heart rate control: neonatal sympathectomy with 6-hydroxydopamine. (1989) (22)
Neonatal parathion exposure disrupts serotonin and dopamine synaptic function in rat brain regions: modulation by a high-fat diet in adulthood. (2009) (22)
Effects of Prenatal Dexamethasone or Terbutaline Exposure on Development of Neural and Intrinsic Control of Heart Rate (1989) (22)
Role of sympathetic neurons in biochemical and functional development of the kidney: neonatal sympathectomy with 6-hydroxydopamine. (1988) (22)
Adolescent nicotine exposure alters cardiac autonomic responsiveness: β-adrenergic and m2-muscarinic receptors and their linkage to adenylyl cyclase (2000) (22)
beta Adrenergic control of c-fos protooncogene expression in developing rat brain regions. (1994) (22)
PERINATAL DIAZINON EXPOSURE COMPROMISES THE DEVELOPMENT OF ACETYLCHOLINE AND SEROTONIN SYSTEMS. (2019) (22)
Effect of transient hypoxia on oxygenation of the developing rat brain: relationships among haemoglobin saturation, autoregulation of blood flow and mitochondrial redox state. (1989) (21)
Unrelated developmental neurotoxicants elicit similar transcriptional profiles for effects on neurotrophic factors and their receptors in an in vitro model. (2010) (21)
Are developing β-adrenoceptors able to desensitize? Acute and chronic effects of β-agonists in neonatal heart and liver (2002) (21)
Visual recognition memory and auditory brainstem response in infant rhesus monkeys exposed perinatally to environmental tobacco smoke (2007) (21)
Reduced inhibitory effect of imipramine on radiolabeled serotonin uptake into platelets in geriatric depression (1989) (21)
Prenatal cocaine and cell development in rat brain regions: Effects on ornithine decarboxylase and macromolecules (1993) (21)
Perinatal exposure to environmental tobacco smoke alters cell signaling in a primate model: autonomic receptors and the control of adenylyl cyclase activity in heart and lung. (2000) (21)
Chlorpyrifos developmental neurotoxicity: interaction with glucocorticoids in PC12 cells. (2012) (20)
Ontogeny of β-adrenoceptor/adenylyl cyclase desensitization mechanisms: the role of neonatal innervation (1996) (20)
Impaired morphological development of the dorsal cochlear nucleus in hamsters treated postnatally with α -difluoromethylornithine (1987) (20)
Fetal dexamethasone exposure affects basal ornithine decarboxylase activity in developing rat brain regions and alters acute responses to hypoxia and maternal separation. (1991) (20)
Effects of early postnatal guanethidine administration on adrenal medulla and brain of developing rats. (1976) (20)
Acute stimulation of ornithine decarboxylase in neonatal rat brain regions by nicotine: a central receptor-mediated process? (1991) (19)
Development of central control of adrenal catecholamine biosynthesis and release (1982) (19)
Cholinergic receptor subtypes in the olfactory bulbectomy model of depression (2006) (19)
Nicotine Exposure in Adolescence Alters the Response of Serotonin Systems to Nicotine Administered Subsequently in Adulthood (2009) (19)
Critical development periods for inhibition of ornithine decarboxylase by α-difluoromethylornithine: Effects on ontogeny of sensorimotor behavior (1986) (19)
Prenatal nicotine changes the response to postnatal chlorpyrifos: Interactions targeting serotonergic synaptic function and cognition (2015) (19)
Mary Bernheim and the discovery of monoamine oxidase (1999) (19)
Altered localization of choline transporter sites in the mouse hippocampus after prenatal heroin exposure (2004) (19)
Prenatal exposure to propranolol via continuous maternal infusion: effects on physiological and biochemical processes mediated by beta adrenergic receptors in fetal and neonatal rat lung. (1990) (19)
Expression of mRNAs coding for the transforming growth factor-beta receptors in brain regions of euthyroid and hypothyroid neonatal rats and in adult brain. (1997) (19)
Mimicking maternal smoking and pharmacotherapy of preterm labor: Fetal nicotine exposure enhances the effect of late gestational dexamethasone treatment on noradrenergic circuits (2011) (19)
SYNAPTIC VESICLES ISOLATED FROM RAT HEART: l‐[3H]NOREPINEPHRINE UPTAKE PROPERTIES 1 (1979) (19)
Terbutaline impairs the development of peripheral noradrenergic projections: potential implications for autism spectrum disorders and pharmacotherapy of preterm labor. (2013) (19)
Ontogeny of G-protein expression: control by β-adrenoceptors (2000) (19)
Effects of alpha-fluoromethylhistidine (FMH), an irreversible inhibitor of histidine decarboxylase, on development of brain histamine and catecholamine systems in the neonatal rat. (1983) (19)
Atypical Regulation of Hepatic Adenylyl Cyclase and Adrenergic Receptors During a Critical Developmental Period: Agonists Evoke Supersensitivity Accompanied by Failure of Receptor Down-Regulation (1996) (19)
Reversal of chlorpyrifos neurobehavioral teratogenicity in mice by nicotine administration and neural stem cell transplantation (2009) (18)
Inhibition of epinephrine and metaraminol uptake into adrenal medullary vesicles by aralkylamines and alkylamines (1975) (18)
Role of thyroid status in the ontogeny of adrenergic cell signaling in rat brain: beta receptors, adenylate cyclase, ornithine decarboxylase and c-fos protooncogene expression. (1994) (18)
Selective linkage of beta-adrenergic receptors to functional responses in developing rat lung and liver: phosphatidic acid phosphatase, ornithine decarboxylase and lung liquid reabsorption. (1989) (18)
Transcriptional profiles for glutamate transporters reveal differences between organophosphates but similarities with unrelated neurotoxicants (2010) (18)
Regulation of postnatal beta-adrenergic receptor/adenylate cyclase development by prenatal agonist stimulation and steroids: alterations in rat kidney and lung after exposure to terbutaline or dexamethasone. (1990) (18)
Neonatal parathion exposure and interactions with a high-fat diet in adulthood: Adenylyl cyclase-mediated cell signaling in heart, liver and cerebellum (2010) (18)
Maternal smoking and conduct disorder in the offspring. (2013) (18)
Sea urchin embryonic development provides a model for evaluating therapies against β-amyloid toxicity (2008) (17)
Maturation of sympathetic neurotransmission in the rat heart. VI. The effect of neonatal central catecholaminergic lesions. (1980) (17)
Ionic and nucleotide cofactor requirements for uptake of [3H]norepinephrine by rat brain synaptic vesicle preparations. (1978) (17)
Effects of Prenatal Terbutaline Exposure on Cellular Development in Lung and Liver of Neonatal Rat: Ornithine Decarboxylase Activity and Macromolecules (1989) (17)
Prenatal nicotine alters the developmental neurotoxicity of postnatal chlorpyrifos directed toward cholinergic systems: Better, worse, or just “different?” (2015) (17)
Early biochemical detection of adverse effects of a neurobehavioral teratogen: influence of prenatal methylmercury exposure on ornithine decarboxylase in brain and other tissues of fetal and neonatal rat. (1985) (17)
Effects of late prenatal or early postnatal ethanol exposure on ornithine decarboxylase activity in brain and heart of developing rats (1977) (17)
Effects of fetal dexamethasone exposure on postnatal control of cardiac adenylate cyclase: beta-adrenergic receptor coupling to Gs regulatory protein. (1993) (17)
Ultraviolet Photolysis of Chlorpyrifos: Developmental Neurotoxicity Modeled in PC12 Cells (2008) (17)
Presynaptic input regulates development of β-adrenergic control of rat brain ornithine decarboxylase: Effects of 6-hydroxydopamine or propranolol (1991) (17)
Effects of tobacco smoke on PC12 cell neurodifferentiation are distinct from those of nicotine or benzo[a]pyrene. (2014) (17)
Perinatal exposure to methadone: how do early biochemical alterations cause neurofunctional disturbances? (1988) (16)
Overexpression of alpha 2-adrenergic receptors in fetal rat heart: receptors in search of a function. (1992) (16)
Age-dependence of inhibition of rat brain synaptic vesicle [3H]norepinephrine uptake caused by administration of a single dose of reserpine: persistence of inhibition in adults but not in neonates. (1978) (16)
Dexamethasone treatment in utero enhances neonatal cholinergic nerve terminal development in rat brain. (1993) (16)
Critical periods for effects of prenatal reserpine administration on development of rat brain and adrenal medulla (1977) (16)
Effects of neonatal methylmercury exposure n development of nucleic acids and proteins in rat brain: Regional specificity (1985) (16)
Neonatal sympathectomy compromises development of responses of ornithine decarboxylase to hormonal stimulation in peripheral tissues. (1989) (16)
Effects of maternal ethanol ingestion on development of adrenal catecholamines and dopamine-β-hydroxylase in the offspring (1976) (16)
Postnatal methyl mercury exposure: effects on ontogeny of renal and hepatic ornithine decarboxylase responses to trophic stimuli. (1985) (16)
Uptake of serotonin into rat platelets and synaptosomes: comparative structure-activity relationships, energetics and evaluation of the effects of acute and chronic nortriptyline administration (1986) (16)
Stimulation of rat heart ornithine decarboxylase by isoproterenol evidence for post-translational control of enzyme activity? (1982) (16)
Perinatal dietary supplementation with a soy lecithin preparation: Effects on development of central catecholaminergic neurotransmitter systems (1986) (16)
Neuronal Control of Cardiac and Hepatic Macromolecule Synthesis in the Neonatal Rat: Effects of Sympathectomy (1997) (16)
Polyamines as intermediates in developmental neurotoxic events. (1986) (16)
Prenatal dexamethasone augments the neurobehavioral teratology of chlorpyrifos: significance for maternal stress and preterm labor. (2014) (16)
Beta-adrenoceptor control of G protein function in the neonate: determinant of desensitization or sensitization. (2002) (15)
Regulation of neonatal rat lung compliance by beta-adrenergic receptor stimulation: effects of prenatal exposure to terbutaline or dexamethasone. (1990) (15)
Solubilization of a [3H]cimetidine binding site from rat brains. A clonidine-sensitive H-2 receptor subtype? (1981) (15)
BDE99 (2,2',4,4',5-pentabromodiphenyl ether) suppresses differentiation into neurotransmitter phenotypes in PC12 cells. (2013) (15)
Premature development of cardiac sympathetic neurotransmission in the fetal alcohol syndrome. (1981) (15)
Coordination of cell development by the ornithine decarboxylase (ODC)/polyamine pathway as an underlying mechanism in developmental neurotoxic events. (1988) (15)
Fetal dexamethasone exposure sensitizes neonatal rat brain to hypoxia: effects on protein and DNA synthesis. (1991) (15)
Prenatal terbutaline treatment: tissue-selective dissociation of perinatal changes in beta-adrenergic receptor binding from regulation of adenylate cyclase activity. (1991) (15)
Adolescent nicotine administration changes the responses to nicotine given subsequently in adulthood: Adenylyl cyclase cell signaling in brain regions during nicotine administration and withdrawal, and lasting effects (2008) (15)
Organophosphate exposure during a critical developmental stage reprograms adenylyl cyclase signaling in PC12 cells (2010) (14)
Developmental neurotoxicity targeting hepatic and cardiac sympathetic innervation: Effects of organophosphates are distinct from those of glucocorticoids (2011) (14)
Neonatal polyamine depletion by α-difluoromethylornithine: effects on adenylyl cyclase cell signaling are separable from effects on brain region growth (2000) (14)
Development of glucocorticoid receptor regulation in the rat forebrain: Implications for adverse effects of glucocorticoids in preterm infants (2008) (14)
A model of harmine metabolism in the rat. (1970) (14)
Precocious development of sympatho-adrenal function in rats whose mothers received methadone. (1980) (14)
Long-lasting CNS effects of a short-term chemical knockout of ornithine decarboxylase during development: nicotinic cholinergic receptor upregulation and subtle macromolecular changes in adulthood (2003) (14)
Stress in the fetus and newborn. (1988) (13)
Neonatal methylmercury poisoning in the rat: effects on development of peripheral sympathetic nervous system. Neuronal participation in methylmercury-induced cardiac and renal overgrowth. (1984) (13)
Adrenergic modulation of cardiac development in the rat: effects of prenatal exposure to propranolol via continuous maternal infusion. (1990) (13)
Neonatal Nutritional Deprivation or Enhancement: The Cardiac-Sympathetic Axis and its Role in Cardiac Growth and Stress Responses (1988) (13)
Autoradiographic localization of ornithine decar☐ylase in cerebellar cortex of the developing rat with [3H]α-difluoromethylornithine (1986) (13)
Central and sympatho-adrenal responses to insulin in adult and neonatal rats. (1987) (13)
Adverse Benzo[a]pyrene Effects on Neurodifferentiation Are Altered by Other Neurotoxicant Coexposures: Interactions with Dexamethasone, Chlorpyrifos, or Nicotine in PC12 Cells (2013) (13)
Norepinephrine content of the rat kidney during development: alterations induced by perinatal methadone. (1982) (13)
Ornithine decarboxylase and polyamines in developing rat brain and heart: Effects of perinatal hypothyroidism (1984) (13)
Transiently overexpressed alpha2-adrenoceptors and their control of DNA synthesis in the developing brain. (2004) (13)
Trophic control of the ornithine decarboxylase/polyamine system in neonatal rat brain regions: lesions caused by 6-hydroxydopamine produce effects selective for cerebellum. (1990) (13)
Uptake of catecholamines by storage vesicles. (1980) (13)
Adult exposure to insecticides causes persistent behavioral and neurochemical alterations in zebrafish. (2020) (13)
Paternal Δ9-Tetrahydrocannabinol Exposure Prior to Mating Elicits Deficits in Cholinergic Synaptic Function in the Offspring. (2020) (13)
Neonatal central catecholaminergic lesions with intracisternal 6-hydroxydopamine: effects on development of presynaptic and postsynaptic components of peripheral sympathetic pathways and on the ornithine decarboxylase/polyamine system in heart, lung and kidney. (1988) (12)
Additive and synergistic effects of fetal nicotine and dexamethasone exposure on cholinergic synaptic function in adolescence and adulthood: Implications for the adverse consequences of maternal smoking and pharmacotherapy of preterm delivery (2010) (12)
Biochemical and functional alterations in renal and cardiac development resulting from neonatal methyl-mercury treatment (1985) (12)
Adrenal medullary storage vesicles of the spontaneously hypertensive rat. (1975) (12)
Perinatal dietary exposure to soy lecithin: Altered sensitivity to central cholinergic stimulation (1986) (12)
Glucocorticoids accelerate the ontogenetic transition of cardiac ventricular myosin heavy-chain isoform expression in the rat: promotion by prenatal exposure to a low dose of dexamethasone. (1992) (12)
The Developmental Neurotoxicity of Tobacco Smoke Can Be Mimicked by a Combination of Nicotine and Benzo[a]Pyrene: Effects on Cholinergic and Serotonergic Systems (2018) (12)
Convergent control of serotonin transporter expression by glucocorticoids and cocaine in fetal and neonatal rat brain. (1997) (12)
Antimitotic and Cytotoxic Effects of Theophylline in MDA-MB-231 Human Breast Cancer Cells (2000) (12)
Prenatal dexamethasone augments the sex-selective developmental neurotoxicity of chlorpyrifos: implications for vulnerability after pharmacotherapy for preterm labor. (2013) (12)
Imbalances emerge in cardiac autonomic cell signaling after neonatal exposure to terbutaline or chlorpyrifos, alone or in combination. (2005) (12)
Heroin neuroteratogenicity: targeting adenylyl cyclase as an underlying biochemical mechanism. (2001) (12)
Glucocorticoids regulate the development of intracellular signaling: Enhanced forebrain adenylate cyclase catalytic subunit activity after fetal dexamethasone exposure (1993) (12)
Effects of neonatal treatment with 6-aminonicotinamide on basal and isoproterenol-stimulated ornithine decarboxylase activity in cerebellum of the development rat. (1985) (12)
Postnatal nutritional status influences development of cardiac adrenergic receptor binding sites (1988) (12)
Regional differences in brain monoamine oxidase subtypes in an animal model of geriatric depression: effects of olfactory bulbectomy in young versus aged rats (2000) (12)
β-Adrenoceptor modulation of transiently overexpressed α2-adrenoceptors in brain and peripheral tissues: cellular mechanisms underlying the developmental toxicity of terbutaline (2004) (12)
Dose-dependent effect of prenatal dexamethasone treatment on beta-adrenergic receptor coupling to ornithine decarboxylase and cyclic AMP. (1990) (11)
Trophic control of lung development by sympathetic neurons: effects of neonatal sympathectomy with 6-hydroxydopamine. (1988) (11)
Functional consequences of prenatal methylmercury exposure: effects on renal and hepatic responses to trophic stimuli and on renal excretory mechanisms. (1986) (11)
Nonenzymatic role of acetylcholinesterase in neuritic sprouting: regional changes in acetylcholinesterase and choline acetyltransferase after neonatal 6-hydroxydopamine lesions. (2009) (11)
Alterations in the development of catecholamine turnover induced by perinatal methadone: differences in central vs. peripheral sympathetic nervous systems. (1981) (11)
Polyamines in brain and heart of the neonatal rat: effects of inhibitors of ornithine decarboxylase and spermidine synthase. (1984) (11)
Reserpine-like effects of harmine on isolated adrenal medullary vesicles. (1973) (11)
Ontogenetic changes in laminar distribution of ornithine decar☐ylase during development of cerebellar cortex: autoradiographic localization with [3h]α-difluoromethylornithine (1988) (11)
Neonatal dexamethasone treatment leads to alterations in cell signaling cascades controlling hepatic and cardiac function in adulthood. (2010) (11)
Effects of chronic chlorisondamine administration on the sympatho-adrenal axis. (1976) (11)
Effects of neonatal mercuric chloride administration on growth and biochemical development of neuronal and non-neuronal tissues in the rat: comparison with methylmercury. (1984) (11)
Chronic morphine administration alters epinephrine uptake in rat adrenal storage vesicles (1975) (10)
Structure-activity relationships for the reserpine-like actions of derivatives of β-carboline in vitro (1974) (10)
Diazinon and parathion diverge in their effects on development of noradrenergic systems (2017) (10)
Catecholamine synthesis, storage and release in adrenal medulla and whole brain during acute and chronic methadone administration. (1976) (10)
Nicotine administration in adolescence reprograms the subsequent response to nicotine treatment and withdrawal in adulthood: Sex-selective effects on cerebrocortical serotonergic function (2014) (10)
Aging and glucocorticoids: effects on cell signaling mediated through adenylyl cyclase. (1996) (10)
Is There a Critical Period for the Developmental Neurotoxicity of Low-Level Tobacco Smoke Exposure? (2017) (10)
Toxic effects of hypoxia on neonatal cardiac function in the rat: α-adrenergic mechanisms (1987) (10)
Central catecholaminergic lesions in the developing rat: effects of cardiac noradrenaline levels, turnover and release. (1981) (10)
Amyloid precursor protein 96-110 and beta-amyloid 1-42 elicit developmental anomalies in sea urchin embryos and larvae that are alleviated by neurotransmitter analogs for acetylcholine, serotonin and cannabinoids. (2008) (9)
Postnatal alterations in beta-adrenergic receptor binding in rat brain regions after continuous prenatal exposure to propranolol via maternal infusion. (1991) (9)
Maternal methadone administration: deficit in development of alpha-noradrenergic responses in developing rat brain as assessed by norepinephrine stimulation of 33Pi incorporation into phospholipids in vivo. (1982) (9)
Short-term adolescent nicotine exposure in rats elicits immediate and delayed deficits in T-lymphocyte function: critical periods, patterns of exposure, dose thresholds. (2003) (9)
Species differences in alpha 2-adrenergic regulation of platelet adenylate cyclase. (1991) (9)
Adolescents and adults differ in the immediate and long-term impact of nicotine administration and withdrawal on cardiac norepinephrine (2016) (9)
Adolescent nicotine: deficits in immune function. (2001) (9)
Developmental shift from local to central control of norepinephrine release in the cardiac-sympathetic axis: effects of cocaine and related drugs. (1991) (9)
Critical developmental periods for effects of low‐level tobacco smoke exposure on behavioral performance (2018) (9)
Glucocorticoid-targeting of the adenylyl cyclase signaling pathway in the cerebellum of young vs. aged rats (1998) (8)
Methadone inhibits serotonin and norephinephrine uptake into rat brain synaptosomes and synaptic vesicles in vitro but not in vivo. (1978) (8)
Endocrine Control of Synaptic Development in the Sympathetic Nervous System (1986) (8)
Transient postnatal elevation of norepinephrine content and turnover in brain regions of rats exposed to terbutaline prenatally: evidence for autoregulation of noradrenergic development? (1992) (8)
Regulation of brain ornithine decarboxylase activity in the neonatal rat. (1983) (8)
Do catecholamines contribute to the effects of neonatal hypoxia on development of brain and heart? Influence of concurrent α-adrenergic blockade on ornithine decarboxylase activity (1987) (8)
Prenatal dexamethasone, as used in preterm labor, worsens the impact of postnatal chlorpyrifos exposure on serotonergic pathways (2014) (8)
Anomalous regulation of β-adrenoceptor signaling in brain regions of the newborn rat (2006) (8)
Amelioration strategies fail to prevent tobacco smoke effects on neurodifferentiation: Nicotinic receptor blockade, antioxidants, methyl donors. (2015) (8)
[Cholinergic regulation of the sea urchin embryonic and larval development]. (2001) (8)
Developmental effects of alpha-fluoromethylhistidine, an irreversible inhibitor of histidine decarboxylase, on growth and on levels and turnover of catecholamines. (1983) (8)
Binding of amines to purified bovine adrenal medullary storage vesicle membranes. (1973) (8)
Cocaine exacerbates hypoxia-induced cell damage in the developing brain: effects on ornithine decarboxylase activity and protein synthesis. (1994) (8)
Heroin neuroteratogenicity: delayed-onset deficits in catecholaminergic synaptic activity (2003) (7)
Consensus on postnatal deficits: comparability of human and animal findings. (1998) (7)
Trans-synaptic modulation of histamine H-1 receptor development in rat brain (1981) (7)
Dual control of DNA synthesis by alpha- and beta-adrenergic mechanisms in normoxic and hypoxic neonatal rat brain. (1990) (7)
Can intracellular signalling pathways predict developmental abnormalities? (1996) (7)
Effects of MK-801 on DNA synthesis in neonatal rat brain regions under normoxic and hypoxic conditions. (1991) (7)
Prenatal reserpine administration: permanent changes in adrenal tyrosine hydroxylase and dopamine beta-hydroxylase. (1975) (7)
Regulation of beta-adrenergic receptor-mediated processes in fetal rat lung: selective desensitization caused by chronic terbutaline exposure. (1990) (7)
Effects of perinatal exposure to methadone on development of neurotransmission: biochemical bases for behavioral alterations. (1983) (7)
Role of thyroid hormone in the development of beta adrenergic control of ornithine decarboxylase in rat heart and kidney. (1991) (7)
Neural factors in the development of renal function: effect of neonatal central catecholaminergic lesions with 6-hydroxydopamine. (1991) (7)
Neonatal hyperthyroidism causes premature development of baroreceptor-mediated cardiac sympathetic reflexes. (1982) (7)
Sympatho-adrenal development in perinatally addicted rats. (1975) (7)
Prenatal alpha-difluoromethylornithine treatment: effects on postnatal renal growth and function in the rat. (1989) (7)
Alteration by methadone of catecholamine uptake and release in isolated rat adrenomedullary storage vesicles. (1976) (7)
EFFECTS OF RESERPINE ON THE ADRENAL MEDULLA OF THE SPONTANEOUSLY HYPERTENSIVE RAT (1975) (7)
Toxic effects of maternal methadone administration on cardiac development in the neonatal rat: potential participation of altered polyamine levels in growth impairment. (1982) (6)
An intracellular opiate receptor. (1980) (6)
Prenatal drug exposures sensitize noradrenergic circuits to subsequent disruption by chlorpyrifos. (2015) (6)
Ontogeny of G-protein expression: control by beta-adrenoceptors. (2000) (6)
An avian model for the reversal of neurobehavioral teratogenicity with neural stem cells. (2010) (6)
Does mechanism matter? Unrelated neurotoxicants converge on cell cycle and apoptosis during neurodifferentiation. (2012) (6)
Neurobehavioral teratogenicity of sarin in an avian model. (2009) (6)
A Critical Period for the Role of Thyroid Hormone in Development of Renalα-Adrenergic Receptors (1997) (5)
Modulation of hepatic adrenergic receptor ontogeny by thyroid hormone. (1995) (5)
Analysis of polycyclic aromatic hydrocarbon intake in the US adult population from NHANES 2005-2014 identifies vulnerable subpopulations, suggests interaction between tobacco smoke exposure and sociodemographic factors. (2021) (5)
Release of [3H]norepinephrine from synaptic vesicles isolated from rat brain after the intracisternal administration of [3h]norepinephrine: Influence of nucleotides, ions and drugs and destabilization of transmitter storage caused by acute or chronic lithium administration (1980) (5)
Promotional role for glucocorticoids in the development of intracellular signalling: enhanced cardiac and renal adenylate cyclase reactivity to beta-adrenergic and non-adrenergic stimuli after low-dose fetal dexamethasone exposure. (1992) (5)
Impaired development of cerebellar cortex in rats treated postnatally with alpha-difluoromethylornithine. (1985) (5)
Protein Kinase C is a Target for Diverse Developmental Neurotoxicants : Transcriptional Responses to Chlorpyrifos , Diazinon , Dieldrin and Divalent Nickel in PC 12 Cells (2009) (5)
Structural characteristics for inhibition of [3H] norepinephrine uptake into rat brain synaptic vesicles by beta-carboline, indolealkylamine, phenethylamine and n-alkylamine derivatives. (1979) (5)
A critical period for the role of thyroid hormone in development of renal alpha-adrenergic receptors. (1997) (5)
Acute effects of cocaine on ornithine decarboxylase activity in fetal and neonatal rat heart: evidence for cardiotoxicity. (1993) (4)
A mechanism-based complementary screening approach for the amelioration and reversal of neurobehavioral teratogenicity. (2010) (4)
Drug-resistant effect of adenine nucleotides and magnesium on catecholamine efflux from isolated adrenal medullary storage vesicles. (1974) (4)
Cryosurgical denervation of the heart: acute and chronic effects. (1990) (4)
Neurobehavioral anomalies in zebrafish after sequential exposures to DDT and chlorpyrifos in adulthood: Do multiple exposures interact? (2021) (4)
Autoradiographic localization of ornithine decarboxylase in cerebellar cortex of the developing rat with [3H]alpha-difluoromethylornithine. (1986) (4)
Maturation of sympathetic neurotransmission in the rat heart--III. Developmental changes in reserpine inhibition of norepinephrine uptake into isolated synaptic vesicles. (1980) (4)
Induction of rat kidney ornithine decarboxylase by nicotinamide without a concomitant increase in DNA synthesis. (1986) (4)
Persisting effects of early postnatal diazinon exposure on emotional reactivity in rats (2006) (3)
Does terbutaline damage the developing heart? (2003) (3)
The cardiac-sympathetic axis as a teratological model. (1983) (3)
Maturation of sympathetic neurotransmission in the rat heart. IV. Effects guanethidine-induced sympathectomy on neonatal development of synaptic vesicles, synaptic terminal function and heart growth. (1981) (3)
Prenatal exposure to methylmercury alters development of adrenergic receptor binding sites in peripheral sympathetic target tissues. (1987) (3)
Are developing beta-adrenoceptors able to desensitize? Acute and chronic effects of beta-agonists in neonatal heart and liver. (2002) (3)
Immediate decline in DNA synthesis in neonatal rat lung caused by exposure to 100% oxygen. (1993) (3)
pH dependence of [3H]norepinephrine uptake into catecholamine storage vesicles isolated from rat brain, heart and adrenal medulla. (1981) (3)
Long-term cognitive effects of low-level developmental organophosphate pesticide exposure: Divergent effects of chlorpyrifos, diazinon and parathion (2008) (3)
Receptors for abused drugs: development and plasticity. (2000) (3)
Developmental neurotoxicity resulting from pharmacotherapy of preterm labor, modeled in vitro: Terbutaline and dexamethasone, separately and together. (2018) (3)
Does growth impairment underlie the adverse effects of dexamethasone on development of noradrenergic systems? (2018) (2)
Morphine-reserpine interactions in the adrenal medulla. (1976) (2)
Generation of reactive oxygen species by xanthine derivatives in MDA‐MB‐231 human breast cancer cells (2001) (2)
Corrigendum to "The Developmental Neurotoxicity of Tobacco Smoke Can Be Mimicked by a Combination of Nicotine and Benzo[a]pyrene: Effects on Cholinergic and Serotonergic Systems". (2019) (2)
Inhibitory Effect of Formononetin Isolated from Ku Shen (Radix Sophorae Flavescentis) on IgE production of B cells (2011) (2)
Paternal Cannabis Exposure Prior to Mating, but Not Δ9-Tetrahydrocannabinol, Elicits Deficits in Dopaminergic Synaptic Activity in the Offspring. (2021) (2)
INDIRECTAND DIRECTINHIBITION OF DOPAMINEP-HYDROXYLASE BYAMPHETAMINE INSTORAGEVESICLESAND SYNAPTOSOMES (1976) (2)
The developmental switch in ventricular myosin expression in vivo is not triggered by an increase in cyclic AMP. (1995) (2)
Cardiovascular and Respiratory Effects of Harmine (1970) (1)
Development of prejunctional alpha 2 adrenergic receptor mediated feedback control of the pressor response to sympathetic nerve stimulation in hypertensive and normotensive rats. (1988) (1)
Alterations in Platelet [3H]-Imipramine Binding, 5HT Uptake and Plasma α1-acid Glycoprotein Concentrations in Patients with Major Depression (1991) (1)
Structure-activity relationships for the reserpine-like actions of derivatives of beta-carboline in vitro. (1974) (1)
Developmental Effects of Nicotine (1995) (1)
Late-emerging cognitive impairment in male rats after neonatal parathion exposure (2009) (1)
Round Table 2. Consensus on Postnatal Deficits: Comparability of Human and Animal Findings (1998) (1)
Persistent Neurobehavioral and Neurochemical Anomalies in Middle-Aged Rats after Maternal Diazinon Exposure. (2022) (1)
TERBUTALINE IMPAIRS THE DEVELOPMENT OF PERIPHERAL NORADRENERGIC PROJECTIONS: IMPLICATIONS FOR AUTISM SPECTRUM DISORDERS AND PHARMACOTHERAPY OF PRETERM LABOR (2013) (1)
SECRETION AND RECOVERY OF CATECHOLAMINES BY THE ADRENAL MEDULLA**The work reported here was supported by grants from the United States Public Health Service AM05427 and MH23278 and from the Council for Tobacco Research—U.S.A. (1973) (1)
cessation during pregnancy The use of pharmacotherapies for smoking (2007) (1)
Complementary zebrafish and rat models of developmental neurobehavioral toxicity: The case of organophosphate pesticide exposure (2007) (1)
Ontogenetic transition of cardiac myosin heavy chain isoforms in rat ventricle: effects of fetal exposure to beta-adrenergic agonists or antagonists. (1992) (1)
Inhibitory Effect of Sub-fractions containing mainly flavonoids in KuShen (Radix Sophorae Flavescentis) on Airway Smooth Muscle Contraction (2011) (1)
Toxic effects of hypoxia on neonatal cardiac function in the rat: alpha-adrenergic mechanisms. (1987) (1)
p-Chlorophenylalanine-induced enhancement of the effects of morphine on the adrenal medulla. (1976) (1)
Synaptic development in brains of rats exposed perinatally to ethanol (1980) (1)
Concerning "Absence of neurotoxicity with medicinal grade terbutaline in the rat model," by M.Y. Owens, K.L. Wallace, N. Mamoon, J. Wyatt-Ashmead and W.A. Bennett. (2011) (1)
Effects of prenatal cocaine exposure on development of rat cardiac adrenergic receptors and their control of adenylate cyclase activity (1992) (1)
Maturation of the Sympathetic Nervous System: Role in Neonatal Physiological Adaptations and in Cellular Development of Peripheral Tissues (1990) (1)
Macromolecular Levels, Dna Synthesis and Ornithine Decarboxylase Activity in Leg Muscles From 6-Mercaptopurine-Treated Rats (1986) (1)
Research report A in PKCg in the mouse hippocampus after prenatal exposure to heroin: a link from cell signaling to behavioral outcome (2003) (1)
Letter: Carotid body chemoreceptors. (1975) (1)
A simplified method for isocratic HPLC analysis of polyamines (1985) (1)
Sex-selective interaction of prenatal nicotine with neonatal chlorpyrifos on novel object recognition in rats (2014) (0)
Reply to Juberg: Using the biologically based dose response to compare exposures across species (2012) (0)
Avian Models for Neurobehavioral Teratogenicity and Its Reversal by Stem Cell Transplantation (2011) (0)
Beta-Adrenergic Receptors Regulating Growth and Replication of Breast Cancer Cells: Basic and Therapeutic Implications (2000) (0)
Abstract D093: Who carries the excess cancer risk burden: Implications of disparities in polycyclic aromatic hydrocarbon exposure (2020) (0)
Marino Autism Research Institute Scientific Symposium: Drug and Chemical Exposures in Animal Models Related to ASD (2008) (0)
Recovery of catecholamine stores following secretion by the adrenal medulla (1973) (0)
<AT>Diverse Neurotoxicants Target the Differentiation of Embryonic Neural Stem Cells into Neuronal and Glial Phenotypes  (2016) (0)
DEVELOPMENT OF SYMPATHETIC NERVE SUPPLIES TO HEART AND ADRENAL MEDULLA OF NEONATAL RAT (1979) (0)
Overexpression oftheHighAffinity Choline Transporter inCortical Regions Affected byAlzheimer's Disease Evidence fromRapidAutopsyStudies (1994) (0)
receptor expression and function in developing heart -Adrenergic modulation of muscarinic cholinergic (2016) (0)
Perspectives in Pharmacology Ontogenesis of (cid:1) -Adrenoceptor Signaling: Implications for Perinatal Physiology and for Fetal Effects of Tocolytic Drugs (2003) (0)
Volume contents and author index (1984) (0)
Developmental exposure to the flame retardant, triphenyl phosphate, causes long‐lasting neurobehavioral and neurochemical dysfunction (2022) (0)
Neuronal, trophic and endocrine effects of nicotine (1994) (0)
Does pharmacotherapy of preterm labor sensitize the brain to neurotoxicants? Sequential exposure to dexamethasone and chlorpyrifos (2012) (0)
Can intracellular signalling pathways predict developmental a b n o rm a I iti e s ? Sensitivity of the adenylyl cyclase / c-fos protooncogene cascade to fbadrenergic agonists and glucocorticoids in foetal rat (2007) (0)
Biochemical and functional alterations in renal and cardiac development resulting from neonatal methylmercury treatment. (1985) (0)
WITHDRAWN: NBTS 2012 abstracts. (2012) (0)
Response to the letter of Hanley et al. ([1999] Teratology 59:323-324), concerning the article by Roy et al. ([1998] Teratology 58:62-68) (1999) (0)

This paper list is powered by the following services:

What Schools Are Affiliated With Theodore A. Slotkin?

Theodore A. Slotkin is affiliated with the following schools:

Duke University

Theodore A. Slotkin's Academic­Influence.com Rankings

Theodore A. Slotkin's Degrees

Why Is Theodore A. Slotkin Influential?

Theodore A. Slotkin's Published Works

Published Works

What Schools Are Affiliated With Theodore A. Slotkin?

Theodore A. Slotkin's AcademicInfluence.com Rankings