Takaaki Aoyagi
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Takaaki Aoyagi's Degrees
- PhD Pharmaceutical Sciences Imperial University of Japan
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(Suggest an Edit or Addition)Takaaki Aoyagi's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Bestatin, an inhibitor of aminopeptidase B, produced by actinomycetes. (1976) (662)
- Pepstatin, a new pepsin inhibitor produced by Actinomycetes. (1970) (600)
- Leupeptins, new protease inhibitors from Actinomycetes. (1969) (242)
- Biological activities of leupeptins. (1969) (207)
- Amastatin, an inhibitor of aminopeptidase A, produced by actinomycetes. (1978) (193)
- Inhibition of aminopeptidase B and leucine aminopeptidase by bestatin and its stereoisomer. (1976) (184)
- Diprotins A and B, inhibitors of dipeptidyl aminopeptidase IV, produced by bacteria. (1984) (175)
- A THERMOLYSIN INHIBITOR PRODUCED BY ACTINOMYCETES: PHOSPHORAMIDON (1973) (157)
- Synthesis and structure-activity relationships of bestatin analogues, inhibitors of aminopeptidase B. (1977) (145)
- Enhancement of delayed-type hypersensitivity by bestatin, an inhibitor of aminopeptidase B and leucine aminopeptidase. (1976) (142)
- Effect of pepstatin on acid proteases. (1971) (141)
- Antipain, a new protease inhibitor isolated from actinomycetes. (1972) (134)
- The structure of bestatin. (1976) (127)
- Effect of bestatin on mouse immune system and experimental murine tumors. (1980) (125)
- GHYMOSTATIN, A NEW GHYMOTRYPSIN INHIBITOR PRODUCED BY ACTINOMYGETES (1970) (117)
- Valilactone, an inhibitor of esterase, produced by actinomycetes. (1978) (110)
- Hydrogen peroxide-mediated degradation of protein: different oxidation modes of copper- and iron-dependent hydroxyl radicals on the degradation of albumin. (1997) (107)
- Aminopeptidase activities on the surface of mammalian cells. (1976) (107)
- Nagstatin, a new inhibitor of N-acetyl-beta-D-glucosaminidase, produced by Streptomyces amakusaensis MG846-fF3. Taxonomy, production, isolation, physico-chemical properties and biological activities. (1992) (104)
- The structure of pepstatin. (1970) (99)
- Biological activity of pepstatins, pepstanone A and partial peptides on pepsin, cathepsin D and renin. (1972) (97)
- Letter: Elastatinal, a new elastase inhibitor produced by actinomycetes. (1973) (93)
- The structure of nagstatin, a new inhibitor of N-acetyl-beta-D-glucosaminidase. (1992) (87)
- Mannostatins A and B: new inhibitors of alpha-D-mannosidase, produced by Streptoverticillium verticillus var. quintum ME3-AG3: taxonomy, production, isolation, physico-chemical properties and biological activities. (1989) (85)
- Production of actinonin, an inhibitor of aminopeptidase M, by actinomycetes. (1985) (84)
- Purification and characterization of a sialidase inhibitor, siastatin, produced by Streptomyces. (1974) (83)
- Purification by affinity chromatography using amastatin and properties of aminopeptidase A from pig kidney. (1980) (80)
- Plipastatins: new inhibitors of phospholipase A2, produced by Bacillus cereus BMG302-fF67. III. Structural elucidation of plipastatins. (1986) (80)
- Plipastatins: new inhibitors of phospholipase A2, produced by Bacillus cereus BMG302-fF67. I. Taxonomy, production, isolation and preliminary characterization. (1986) (78)
- Isolation and characterization of leupeptins produced by Actinomycetes. (1969) (77)
- Studies on inhibitory effect of phosphoramidon and its analogs on thermolysin. (1975) (75)
- Production by actinomycetes of (S,S)-N,N'-ethylenediamine-disuccinic acid, an inhibitor of phospholipase C. (1984) (70)
- Esterastin, an inhibitor of esterase, produced by actinomycetes. (1978) (68)
- Mechanism of inhibition of pepsin by pepstatin. (1972) (67)
- Probestin, a new inhibitor of aminopeptidase M, produced by Streptomyces azureus MH663-2F6. I. Taxonomy, production, isolation, physico-chemical properties and biological activities. (1990) (62)
- Forphenicine, and inhibitor of alkaline phosphatase produced by actinomycetes. (1978) (57)
- Production of 2-methyl-4[3H]-quinazolinone, an inhibitor of poly(ADP-ribose) synthetase, by bacterium. (1991) (57)
- Plipastatins: new inhibitors of phospholipase A2, produced by Bacillus cereus BMG302-fF67. II. Structure of fatty acid residue and amino acid sequence. (1986) (56)
- Poststatin, a new inhibitor of prolyl endopeptidase, produced by Streptomyces viridochromogenes MH534-30F3. I. Taxonomy, production, isolation, physico-chemical properties and biological activities. (1991) (55)
- Effect of protease inhibitors of actinomycetes on lysosomal peptide-hydrolases from swine liver. (1971) (53)
- Arphamenines A and B, new inhibitors of aminopeptidase B, produced by bacteria. (1983) (50)
- Bestatin, a new specific inhibitor of aminopeptidases, enhances activation of small lymphocytes by concanavalin A. (1977) (49)
- Various enzyme activities in muscle and other organs of dystrophic mice. (1981) (48)
- An enzyme inhibitor, panosialin, produced by Streptomyces. II. Chemistry of panosialin, 5-alkylbenzene-1,3-disulfates. (1971) (47)
- Phebestin, a new inhibitor of aminopeptidase N, produced by Streptomyces sp. MJ716-m3. (1997) (46)
- The structure and activity of leupeptins and related analogs. (1971) (46)
- Increased gamma-aminobutyrate aminotransferase activity in brain of patients with Alzheimer's disease. (1990) (46)
- Immunosuppressive activities of deoxyspergualin. II. The effect on the antibody responses. (1987) (44)
- The chemical synthesis of bestatin. (1976) (43)
- Deficiency of kallikrein-like enzyme activities in cerebral tissue of patients with alzheimer's disease (1990) (43)
- Enzyme inhibitors in relation to cancer therapy. (1977) (43)
- Pyridindolol, a new beta-galactosidase inhibitor produced by actinomycetes. (1975) (43)
- Inhibitory effects of phosphoramidon on neutral metalloendopeptidases and its application on affinity chromatography. (1975) (41)
- Structural studies on ebelactone A and B, esterase inhibitors produced by actinomycetes. (1982) (39)
- Inhibition of tumor cell invasion and matrix degradation by aminopeptidase inhibitors. (1996) (39)
- Ebelactone, an inhibitor of esterase, produced by actinomycetes. (1980) (38)
- Chymostatin, a new chymotrypsin inhibitor produced by actinomycetes. (1970) (37)
- X-ray structure determination of (2S, 3R)-3-amino-2-hydroxy-4-phenylbutanoic acid, a new amino acid component of bestatin. (1976) (37)
- Leuhistin, a new inhibitor of aminopeptidase M, produced by Bacillus laterosporus BMI156-14F1. I. Taxonomy, production, isolation, physico-chemical properties and biological activities. (1991) (37)
- Poststatin, a new inhibitor of prolyl endopeptidase, produced by Streptomyces viridochromogenes MH534-30F3. II. Structure determination and inhibitory activities. (1991) (36)
- Studies on effects of forphenicinol on immune responses. (1982) (36)
- The structure of esterastin, an inhibitor of esterase. (1978) (36)
- Therapeutic effect of 15‐deoxyspergualin on the progression of lupus nephritis in MRL mice. I. Immunopathological analyses (1990) (36)
- Effects of hydrolase inhibitors on fertilization of sea urchins: I. Protease inhibitors (1979) (35)
- Fluostatins A and B, new inhibitors of dipeptidyl peptidase III, produced by Streptomyces sp. TA-3391. I. Taxonomy of producing strain, production, isolation, physico-chemical properties and biological properties. (1998) (34)
- Aminopeptidase activities on the surface of mammalian cells and their alterations associated with transformation. (1978) (34)
- Apoptosis to HL-60 by humulone. (1997) (34)
- beta-Galactosidase-inhibiting new isoflavonoids produced by actinomycetes. (1979) (33)
- The structure of elastatinal, an elastase inhibitor of microbial origin. (1975) (33)
- Foroxymithine, a new inhibitor of angiotensin-converting enzyme, produced by actinomycetes. (1985) (33)
- Aminopeptidase N (CD13, EC 3.3.4.11.2) occurs on the surface of resting and concanavalin A-stimulated lymphocytes. (1993) (30)
- Structure determination of mannostatins A and B. (1989) (29)
- Letter: New pepstatins, pepstatins Bu, Pr and Ac produced by Streptomyces. (1973) (29)
- Benastatins A and B, new inhibitors of glutathione S-transferase, produced by Streptomyces sp. MI384-DF12. I. Taxonomy, production, isolation, physico-chemical properties and biological activities. (1992) (29)
- Probestin, a new inhibitor of aminopeptidase M, produced by Streptomyces azureus MH663-2F6. II. Structure determination of probestin. (1990) (28)
- ACTIVITY OF BESTATIN: ENHANCEMENT OF IMMUNE RESPONSES AND ANTITUMOR EFFECT (1981) (28)
- Siastatin B, a potent neuraminidase inhibitor: the total synthesis and absolute configuration (1988) (28)
- Effects of ebelactone B, a lipase inhibitor, on intestinal fat absorption in the rat. (1996) (27)
- Antiviral effect of formycin and formycin B. (1966) (26)
- Cyclooctatin, a new inhibitor of lysophospholipase, produced by Streptomyces melanosporofaciens MI614-43F2. Taxonomy, production, isolation, physico-chemical properties and biological activities. (1992) (26)
- The structure of cyclooctatin, a new inhibitor of lysophospholipase. (1992) (25)
- Immunosuppressive activities of deoxyspergualin. I. Effect of the long-term administration of the drug on the development of murine lupus. (1987) (25)
- Pyrizinostatin: a new inhibitor of pyroglutamyl peptidase. (1992) (25)
- A facile synthesis of bestatin. (1983) (24)
- Differential effect of various inhibitors on four types of rat sialidase (1993) (24)
- Protease-inhibitory activities of leupeptin analogues. (1988) (23)
- Release of a plasma membrane-bound triaminopeptidase activity from mammalian cells by thermolysin. (1978) (23)
- Fluostatins A and B, new inhibitors of dipeptidyl peptidase III, produced by Streptomyces sp. TA-3391. II. Structure determination. (1998) (23)
- Pyrostatins A and B, new inhibitors of N-acetyl-beta-D-glucosaminidase, produced by Streptomyces sp. SA-3501. (1995) (23)
- Production of (S)-alpha-benzylmalic acid, inhibitor of carboxypeptidase A by actinomycetes. (1984) (22)
- Cysfluoretin, a new inhibitor of glutathione S-transferase, produced by Streptomyces sp. MI384-DF12. (1993) (22)
- The effects of bestatin, a microbial aminopeptidase inhibitor, on epidermal growth factor-induced DNA synthesis and cell division in primary cultured hepatocytes of rats. (1989) (22)
- Structure and Chemical Synthesis of Amastatin (1979) (21)
- Inhibition of tumor cell invasion in the Boyden chamber assay by a mannosidase inhibitor, mannostatin A. (1993) (21)
- Histargin, a new inhibitor of carboxypeptidase B, produced by actinomycetes. (1984) (21)
- Bequinostatins A and B new inhibitors of glutathione S-transferase, produced by Streptomyces sp. MI384-DF12. Production, isolation, structure determination and biological activities. (1993) (20)
- Letter: A thermolysin inhibitor produced by Actinomycetes: phospholamidon. (1973) (20)
- Structure of pyridindolol, inhibitor of beta-galactosidase. (1975) (20)
- Abnormality of the post-proline-cleaving enzyme activity in mice with systemic lupus erythematosus-like syndrome. (1985) (20)
- Purification and properties of N-formylmethionine aminopeptidase from rat liver. (1980) (19)
- Analgesic effect of actinonin, a new potent inhibitor of multiple enkephalin degrading enzymes. (1987) (19)
- Composite effects of actinonin when inhibiting enkephalin-degrading enzymes. (1987) (19)
- Benastatins A and B, new inhibitors of glutathione S-transferase, produced by Streptomyces sp. MI384-DF12. II. Structure determination of benastatins A and B. (1992) (19)
- The structure of forphenicine. (1978) (19)
- Isoflavone rhamuniosides inhibitors of beta-galactosidase produced by actinomycetes. (1975) (19)
- Lupus nephropathy in New Zealand F1 hybrid mice treated by (-)15-deoxyspergualin. (1988) (18)
- Biosynthetic studies of ebelactone A and B by 13C NMR spectrometry. (1982) (18)
- Purification and Characterization of Streptomyces Sialidases (1974) (18)
- Bestatin, a microbial aminopeptidase inhibitor, inhibits DNA synthesis induced by insulin or epidermal growth factor in primary cultured rat hepatocytes. (1985) (18)
- Effect of antipain on lysosomal peptide-hydrolases from swine liver. (1972) (17)
- p-Hydroxyphenylacetaldoxime, an inhibitor of beta-galactosidase, produced by actinomycetes. (1979) (16)
- SYNTHESIS AND STRUCTURE-ACTIVITY RELATIONS OF BESTATIN ANALOGS, INHIBITORS OF AMINOPEPTIDASE B (1977) (16)
- Two different modes of enzymatic changes in serum with progression of Duchenne muscular dystrophy. (1983) (15)
- Relationship between enhancement of morphine analgesia and inhibition of enkephalinase by 2S, 3R 3-amino-2-hydroxy-4-phenylbutanoic acid derivatives. (1982) (15)
- Benarthin: a new inhibitor of pyroglutamyl peptidase. I. Taxonomy, fermentation, isolation and biological activities. (1992) (15)
- Chapter 12. Small Molecular Protease Inhibitors and Their Biological Effects (1990) (14)
- Sulphostin, a potent inhibitor for dipeptidyl peptidase IV from Streptomyces sp. MK251-43F3. (2001) (14)
- HYDROXYPEPSTATIN, A NEW PEPSTATIN PRODUCED BY STREPTOMYCES (1973) (14)
- Sialic acid residues exposed on mammalian cell surface: the effect of adsorption of denatured virus particles. (1974) (14)
- The structure of arphamenines A and B. (1983) (14)
- Bequinostatins C and D, new inhibitors of glutathione S-transferase, produced by Streptomyces sp. MI384-DF12. (1993) (13)
- Aminopeptidase activity of an antitumor antibiotic, C-1027. (1992) (13)
- Deficiency of fibrinolytic enzyme activities in the serum of patients with Alzheimer-type dementia (1992) (13)
- An enzyme inhibitor, panosialin, produced by Streptomyces. I. Biological activity, isolation and characterization of panosialin. (1971) (13)
- Japanese map of the earwax gene frequency: a nationwide collaborative study by Super Science High School Consortium (2009) (13)
- Decreased serum levels of various hydrolytic enzymes in patients with rheumatoid arthritis. (1984) (13)
- Benadrostin, new inhibitor of poly(ADP-ribose) synthetase, produced by actinomycetes. II. Structure determination. (1988) (12)
- Microbial serine carboxypeptidase inhibitors--comparative analysis of actions on homologous enzymes derived from man, yeast and wheat. (2004) (12)
- Biosynthetic studies on pepstatin. Biosynthesis of (3s, 4s)-4-amino-3-hydroxy-6-methylheptanoic acid moiety. (1974) (12)
- Inhibitors of aminopeptidase B suppress the development of hypertension in spontaneously hypertensive rats. (1986) (12)
- Leuhistin, a new inhibitor of aminopeptidase M, produced by Bacillus laterosporus BMI156-14F1. II. Structure determination of leuhistin. (1991) (12)
- Poststatin, a new inhibitor of prolyl endopeptidase. V. Endopeptidase inhibitory activity of poststatin analogues. (1996) (12)
- Synthesis and Structure-activity Relationships of Amastatin Analogues, Inhibitors of Aminopeptidase A (1982) (12)
- Change of enzyme activities during the early stage of influenza virus infection. (1974) (11)
- Systemic enzymatic changes in guinea pigs suffering from experimental allergic encephalomyelitis. (1983) (11)
- Inhibitory activity of pyridindolol on beta-galactosidase. (1976) (11)
- Antiviral effect of formycin derivatives. (1967) (11)
- Benadrostin, new inhibitor of poly(ADP-ribose) synthetase, produced by actinomycetes. I. Taxonomy, production, isolation, physico-chemical properties and biological activities. (1988) (10)
- Oscillation of enzyme networks in spleen triggered by an immunopotentiator, bestatin. (1984) (10)
- The structure of histargin. (1984) (10)
- The relationships between enzyme inhibitors and function of mammalian cells. (1981) (10)
- Piperastatin A, a new selective serine carboxypeptidase inhibitor produced by actinomycete. I. Taxonomy, production, isolation and biological activities. (1996) (10)
- Cultivation of mycobacteria rocked in non-protein medium containing a high concentration of tween 80. (1959) (10)
- Biosynthetic studies of arphamenines A and B. (1984) (10)
- Biochemical studies of the hatching process in sea urchin embryos. I. Effects of protease inhibitors (1979) (10)
- The conformational studies of plipastatin A1 by 400 MHz proton magnetic resonance. (1986) (9)
- Prophylactic and Therapeutic Effect of Bactobolin on Autoimmune Encephalomyelitis (1987) (9)
- Poststatin, a new inhibitor of prolyl endopeptidase. VIII. Endopeptidase inhibitory activity of non-peptidyl poststatin analogues. (1996) (9)
- Intramuscular enzyme abnormalities of dystrophic chickens compared to those of dystrophic mice. (1981) (9)
- Induction of Apoptosis and Cell Cycle Arrest in Mouse Colon 26 Cells by Benastatin A (2000) (9)
- Relation of blood glucose levels to the changes in plasma levels of various hydrolytic enzymes in diabetic patients. (1985) (9)
- Biosynthesis of benastatin A. (1992) (9)
- Toxicological and immunological evaluation of the immunosuppressant 15-deoxyspergualin in BALB/c mice: an in vivo and in vitro study. (1991) (8)
- Structure-activity relationships among derivatives of arphamenines, inhibitors of aminopeptidase B. (1984) (8)
- Biosynthetic study of leuhistin, a new inhibitor of aminopeptidase M. (1991) (8)
- Different enzymatic oscillations in vivo caused by the stereoisomers of an aminopeptidase inhibitor, bestatin. (1984) (8)
- Benarthin: a new inhibitor of pyroglutamyl peptidase. II. Physico-chemical properties and structure determination. (1992) (8)
- Poststatin, a new inhibitor of prolyl endopeptidase. IV. The chemical synthesis of poststain. (1996) (8)
- Poststatin, a new inhibitor of prolyl endopeptidase. VI. Endopeptidase inhibitory activity of poststatin analogues containing pyrrolidine ring. (1996) (8)
- Production of acetyl-L-leucyl-L-argininal, inhibitor of dipeptidyl aminopeptidase III by bacteria. (1984) (8)
- Effect of phosphoramidon on protection against corneal ulcer caused by elastase and protease from Pseudomonas aeruginosa. (1982) (8)
- Poststatin, a new inhibitor of prolyl endopeptidase. VII. N-cycloalkylamide analogues. (1996) (8)
- Relation between in vivo effects and in vitro effects of serine and thiol proteinase inhibitors. (1983) (8)
- Low-Molecular-Weight Protease Inhibitors of Microbial Origin (1993) (8)
- Poststatin, a new inhibitor of prolyl endopeptidase. III. Optical resolution of 3-amino-2-hydroxyvaleric acid and absolute configuration of poststatin. (1996) (8)
- Brief Communication: Effect of Protease Inhibitors on Focus Formation by Murine Sarcoma Virus (1975) (8)
- Increase in aminobutyrate aminotransferase and cholineacetyltransferase in cerebrum of aged rats. (1990) (7)
- Piperastatin B: a new selective serine carboxypeptidase inhibitor from Streptomyces lavendofoliae MJ908-WF13. (1996) (7)
- Feedback analysis of the behavior of the renin‐angiotensin system under inhibition of angiotensin‐converting enzyme (1988) (7)
- Dissociation between serine proteinases and proline related enzymes in spleen of MRL mouse as a model of systemic lupus erythematodes. (1987) (7)
- Influence of angiotensin-converting enzyme inhibitor, foroxymithine, on dynamic equilibrium around the renin-angiotensin system in vivo. (1985) (7)
- Epostatin, new inhibitor of dipeptidyl peptidase II, produced by streptomyces sp. MJ995-OF5 II. Structure elucidation. (1998) (7)
- Isolation of alpha-aminoacyl arginines in screening of aminopeptidase B inhibitors. (1980) (6)
- Synthesis of arphamenine A and epi-arphamenine A. (1983) (6)
- TAXONOMY , PRODUCTION , ISOLATION , PHYSICO-CHEMICAL PROPERTIES AND BIOLOGICAL ACTIVITIES (2006) (6)
- Suppression of experimental autoimmune myasthenia gravis with new immunosuppressants: 15-deoxyspergualin and actinobolin (1992) (6)
- Age-dependent decreases in fibrinolytic enzyme activities in serum of healthy subjects. (1994) (6)
- A rapid antibacterial test for mycobacteria using a reverse T type of tube in rocked culture. (1959) (6)
- Effects of deoxyspergualin on dipeptidyl peptidase-II and -IV in the spleen of BXSB mice and MRL/lpr mice during the development of the lupus erythematosus-like syndrome. (1992) (5)
- Alphostatin, an inhibitor of alkaline phosphatase of bovine liver produced by Bacillus megaterium. (1989) (5)
- Trans-4-aminomethylcyclohexanecarboxylic acid as a potent antiplasmin agent. (1965) (5)
- Synthesis of p-hydroxyubenimex. (1987) (5)
- Belactins A and B, new serine carboxypeptidase inhibitors produced by Actinomycete. I. Taxonomy, production, isolation and biological activities. (1995) (5)
- Mechanism of inhibition of pepsin by pepstatin. II. (1974) (5)
- Reversal of established nephropathy in New Zealand B/W F1 mice by 15-deoxyspergualin. (1991) (5)
- Enzymatic Changes in Cerebrospinal Fluid of Patients with Alzheimer-Type Dementia. (1993) (5)
- Synthesis of histargin and related compounds and their inhibition of enzymes. (1988) (5)
- Epostatin, new inhibitor of dipeptidyl peptidase II, produced by Streptomyces sp. MJ995-OF5. I. Taxonomy of producing strain, fermentation, isolation, physico-chemical properties and biological properties. (1998) (5)
- Benarthin: a new inhibitor of pyroglutamyl peptidase. III. Synthesis and structure-activity relationships. (1992) (4)
- Epostatin, New Inhibitor of Dipeptidyl Peptidase II, Produced by Streptomyces sp. MJ995‐OF5. Part 1. Taxonomy of Producing Strain, Fermentation, Isolation, Physico‐Chemical Properties and Biological Properties. (1998) (4)
- Role of intramuscular enzymatic changes in the development of muscular weakness in rats with experimental allergic neuritis (1984) (4)
- Increased Angiotensin-Converting Enzyme Activity in Essential Hypertension (1990) (4)
- Multiple enzymes related to differentiation of lymphocyte subpopulations in man. (1989) (4)
- Studies on relationships between the structure and the glycosidase-inhibiting activity of HPAAO and its analogs. (1979) (4)
- The dissociation between the plasma levels of aminopeptidases A and B in spontaneously hypertensive rats. (1986) (4)
- Effect of protease inhibitors on focus formation by murine sarcoma virus. (1975) (4)
- Proportionality of protease activities in malignant cells to their metastatic potentials. (1994) (4)
- Effect of panosialin on myxoviruses (2005) (4)
- Changes in relationship between blood glucose level and plasma 1,5-anhydroglucitol level in KK mice. (1989) (4)
- Physiological Roles of Ectoenzymes Indicated by the Use of Aminopeptidase Inhibitors (2002) (4)
- Belactins A and B, new serine carboxypeptidase inhibitors produced by Actinomycete. II. Physico-chemical properties, structure determinations and enzymatic inhibitory activities compared with other beta-lactone containing inhibitors. (1995) (3)
- PURIFICATION AND CHARACTERIZATION OF A SIALIDASE INHIBITOR (2006) (3)
- The Improvement of Productivity and Selective Production of Arphamenines by Addition of Their Biosynthetic Precursors (1984) (3)
- Gangliosides administration causes sugar moiety‐specific enzymatic changes in brain (1991) (3)
- Three main components in plasma proteases and their relation to the renin‐angiotensin system (1990) (3)
- Benastatins C and D, new inhibitors of glutathione S-transferase, produced by Streptomyces sp. MI384-DF12. Production, isolation, structure determination and biological activities. (1993) (3)
- Suppression of the activities of T-lymphocyte-related enzymes in spleen by administration of an immunosuppressant, 15-deoxyspergualin. (1989) (3)
- Dynamic Relationship between Hydrolytic Enzymes and the Immune System in Rheumatic Diseases (1987) (3)
- The absolute configuration of belactin A, a beta-lactone-containing serine carboxypeptidase inhibitor: importance of the beta-lactone structure for serine carboxypeptidase inhibition. (1999) (3)
- THE NATIVE CONSTITUENTS OF ACETONE SOLUBLE NEUTRAL FATS OF MYCOBACTERIUM TUBERCULOSIS BCG (1960) (3)
- Dose-dependent enzyme suppression in spleen induced by GM1 (monosialoganglioside 1) administration to mice. (1992) (3)
- On the fractionation of complex components of Mycobacterium tuberculosis and their biological properties. (1960) (3)
- A new type of major aminopeptidase in bovine brain. (1996) (3)
- The structure of pyrizinostatin. (1992) (3)
- Serum Protease Changes in Spontaneously Hypertensive Rats (1991) (2)
- Cell-free biosynthesis of arphamenine A. (1986) (2)
- Systemic changes in hydrolytic enzyme activities in mice affected with murine leprosy. (1985) (2)
- Dissociation of creatine kinase activity from hydrolytic enzyme activities in muscle of dystrophic mice. (1985) (2)
- Abnormalities of splenic enzyme networks in nude mice. (1984) (2)
- Bestatin Suppresses the Serum Levels of Several Hydrolytic Enzymes in a Patient with Progressive Muscular Dystrophy (1986) (2)
- STRUCTURE OF PYRIDINDOLOL , INHIBITOR OF 13-GALACTOSIDASE (2006) (2)
- Three modes of age-related changes of hydrolytic enzymes in murine brain. (1986) (2)
- Protease inhibitors and biological control (1989) (2)
- Enzymatic changes in dystrophic mice and their age dependency. (1983) (2)
- Similar effects of various low-molecular-weight enzyme inhibitors on enzyme networks in dystrophic mice. (1984) (2)
- Enzymatic changes in various organs of guinea pigs caused by the administration of Freund's complete adjuvant. (1983) (2)
- Piperastatin A, a new selective serine carboxypeptidase inhibitor produced by actinomycete. II. Physico-chemical properties and structure determination. (1996) (2)
- Structure determination of alphostatin, a novel alkaline phosphatase inhibitor. (1989) (2)
- Chemical Nature of a Substance which was extracted from Egg Yolk and reported by Yamane to be Growth-Stimulatory to Mycobacterium tuberculosis. (1958) (1)
- Characterization of myxovirus sialidase (1975) (1)
- PRODUCTION OF PHARMACOLOGICALLY ACTIVE AGENTS FROM MICROBIAL ORIGIN (1981) (1)
- [An outline of enzyme inhibitors]. (1993) (1)
- Taxonomy of Producing Strain , Fermentation , Isolation , Physico-chemical Properties and Biological Properties (2008) (1)
- [Screening, characterization and pharmaceutical and medical application of enzyme inhibitors from microbial origin with low-molecular-weight]. (1996) (1)
- Letter: Hydroxypepstatin, a new peptatin produced by Streptomyces. (1973) (1)
- [Biological activities of protease inhibitors (author's transl)]. (1980) (1)
- [Prolyl endopeptidase inhibitors]. (1993) (1)
- Fluostatins A and B, New Inhibitors of Dipeptidyl Peptidase III, Produced by Streptomyces sp. TA-3391. Part 2. Structure Determination. (1998) (1)
- Biosynthesis of an unusual amino acyl moiety contained in bestatin. (1986) (1)
- [Protease inhibitors (author's transl)]. (1978) (1)
- Screening, Characterization, and Pharmaceutical and Medical Application of Enzyme Inhibitors from Microbial Origin with Low‐ Molecular‐Weight (1997) (1)
- Possible relationship between poly(ADP-ribose)synthetase and formation of antibody against acetylcholine receptors in patients with myasthenia gravis. (1989) (1)
- In vivo actions of bestatin-related compounds in relation to their actions in vitro. (1984) (1)
- Different tendencies of changes in hydrolytic enzyme activities in sera from prostatic cancer patients with or without bone metastasis. (1984) (1)
- A Multivariate Study on Enzymatic Changes in Limb Muscles and Heart Muscle of Dystrophic Mice (1987) (1)
- Relative deficiency of serine proteinase activities in spleen of aged mice (1987) (1)
- Poststatin, a New Inhibitor of Prolyl Endopeptidase. Part 3. Optical Resolution of 3‐Amino‐2‐hydroxyvaleric Acid and Absolute Configuration of Poststatin. (1996) (1)
- Correlation between Disease Stage and Activity of Elastase of PMN Origin in the Serum from IgA Nephropathy Patients. (1998) (0)
- A process for producing trans-4-aminomethylcyclohexane-1-carboxylic acid (1965) (0)
- Low-molecular-weight enzyme inhibitors suppress the development of experimental allergic encephalomyelitis (1984) (0)
- Poststatin, a New Inhibitor of Prolyl Endopeptidase. Part 5. Endopeptidase Inhibitory Activity of Poststatin Analogues. (1997) (0)
- New analgesic agent (1981) (0)
- [The experimental study of epidermal growth factor -effects of epidermal growth factor on the cyclic nucleotide system and protein phosphorylation in pig epidermis- (author's transl)]. (1981) (0)
- Peptides, process for their preparation and their therapeutic use (1978) (0)
- New physiologically active derivatives of esterastins and method for manufacturing the same (1979) (0)
- Leupeptine and their analogues (1969) (0)
- trans-4-aminomethylcyclohexane-1-carboxylic acid and process for preparing (1964) (0)
- Esterastine and production (1978) (0)
- Analgesic action of enkephalinase inhibitor, D-phenylalanyl-2S,3R 3-amino-2-hydroxy-4-phenylbutanoic acid (D-Phe-AHPA) (1983) (0)
- A process for preparing threo-3-amino-2-hydroxy-butanoyl-amino acetic acids, as well as novel intermediates thereto and methods for preparing these (1979) (0)
- Poststatin, a New Inhibitor of Prolyl Endopeptidase. Part 8. Endopeptidase Inhibitory Activity of Non-Peptidyl Poststatin Analogues. (1997) (0)
- THE ROLE OF ENZYME INHIBITORS IN THE BIOLOGICAL CONTROL (1981) (0)
- Pathophysiology and Enzyme Inhibitors—Protease and Inhibitors (1997) (0)
- PIPERASTATIN A, A NEW SELECTIVE SERINE CARBOXYPEPTIDASE INHIBITOR PRODUCED PROPERTIES AND STRUCTURE DETERMINATION BY ACTINOMYCETE 11. PHYSICO-CHEMICAL (1996) (0)
- Difference in enzyme networks between mouse and hamster models of muscular dystrophy. (1984) (0)
- Fluostatins A and B, New Inhibitors of Dipeptidyl Peptidase III, Produced by Streptomyces sp. TA‐3391. Part 1. Taxonomy of Producing Strain, Production, Isolation, Physicochemical Properties and Biological Properties. (1998) (0)
- Suppression of splenic enzyme activities by administration of aminopeptidase N (CD13) inhibitors: relationship between actions in vivo and in vitro. (1994) (0)
- Abnormalities of various serum enzyme activities in patients with congenital adrenal hyperplasia. (1983) (0)
- Physiologically active substances probestine and Prostatin and their production. (1988) (0)
- Role of catabolic enzymes in pathogenesis of anemia in hemodialysis patients (1982) (0)
- The new, physiologically active substance ebelactone and method for manufacturing the same (1981) (0)
- Multivariate analysis of the oscillation of intrarenal enzyme networks induced by aminopeptidase inhibitor. (1985) (0)
- Deficiency of Galactosidase Activity in Multiple Organs in GM2-Deficient Mice (1992) (0)
- Effects of Benadrostin, a Poly (ADP-Ribose) Polymerase Inhibitor, on Apoptosis of HL-60 Induced by 5-Azacytidine (1997) (0)
- Siastatin B, a Potent Neuraminidase Inhibitor: The Total Synthesis and Absolute Configuration. (1989) (0)
- PB130 SIASTATIN B, A POTENT SIALIDASE INHIBITOR : THE TOTAL SYNTHESIS, ABSOLUTE CONFIGURATION AND BIOLOGICAL ACTIVITY (1988) (0)
- Demonstration of in vivo effects of ACE inhibitors by the use of autoregressive modelling. (1989) (0)
- PYROSTATINS A AND B, NEW INHIBITORS OF PRODUCED BY Streptomyces sp. SA-3501 N-ACETYL-B-D-GLUCO SAMINIDASE, (1995) (0)
- Particular Changes in the Activity of Intramuscular Dipeptidyl Peptidase III in Comparison to Those of Other Hydrolytic Enzymes in Dystrophic Mice. (1991) (0)
- MANNOSTATINS A AND B*: NEW INHIBITORS OF o-d-MANNOSIDASE, PRODUCED BY STREPTO VERTICILLIUM VERTICILLUS VAR (2006) (0)
- Use of actinonin for angiogenesis inhibition (1990) (0)
- Enzymatic Changes in Pancreas and Liver of the KK Mouse As an Animal Model of Diabetes Mellitus (1986) (0)
- Modulation of Intracerebral Glycosidase Activities by Intraperitoneal Administration of Glycosidase Inhibitors. (1991) (0)
- [Inhibitory activity of pepstatin against acid protease and a method of estimating acid protease in gastric juice]. (1973) (0)
- Derived from l-argininal and method of preparing (1981) (0)
- Decreased Activities of Serine Proteinases in Spleen of Various Murine Models of Systemic Lupus Erythematodes (1987) (0)
- Alpha-keto-amide derivatives inhibiting protease activity (1991) (0)
- X-RAY OUT PUT (1978) (0)
- Relation of hydrolytic enzymes in spleen to immunological dysregulation in mice. (1986) (0)
- L-argininal derivatives and preparation method (1981) (0)
- A method for producing the trans stereoisomers of 4-aminomethyl-1-carboxylic acid (1964) (0)
- L-argininalderivate, processes for their preparation and pharmaceutical compositions containing them (1981) (0)
- DE~ONSTRATION OF IN VIVO EFFECTS OF ACE INHIBITORS BY THE USE OF (1989) (0)
- Plipastatin, its preparation and use, as well as in the manufacture useful microorganism (1985) (0)
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