Thomas C. Spelsberg
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(Suggest an Edit or Addition)Thomas C. Spelsberg's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Evidence of estrogen receptors in normal human osteoblast-like cells (1988) (822)
- Skeletal effects of estrogen. (1994) (786)
- Human Aortic Valve Calcification Is Associated With an Osteoblast Phenotype (2003) (740)
- Estrogen stimulates gene expression and protein production of osteoprotegerin in human osteoblastic cells. (1999) (678)
- Interleukin-1β and tumor necrosis factor-α, but not interleukin-6, stimulate osteoprotegerin ligand gene expression in human osteoblastic cells (1999) (589)
- Evidence of estrogen receptors in normal human osteoblast-like cells. (1988) (485)
- Stimulation of Osteoprotegerin Ligand and Inhibition of Osteoprotegerin Production by Glucocorticoids in Human Osteoblastic Lineage Cells: Potential Paracrine Mechanisms of Glucocorticoid-Induced Osteoporosis1. (1999) (471)
- Stimulation of osteoprotegerin ligand and inhibition of osteoprotegerin production by glucocorticoids in human osteoblastic lineage cells: potential paracrine mechanisms of glucocorticoid-induced osteoporosis. (1999) (468)
- Development and characterization of a conditionally immortalized human fetal osteoblastic cell line (1995) (467)
- Identification of androgen receptors in normal human osteoblast-like cells. (1989) (448)
- Bisphosphonates directly regulate cell proliferation, differentiation, and gene expression in human osteoblasts. (2000) (391)
- Avian osteoclasts as estrogen target cells. (1991) (388)
- Isolation and characterization of osteoblast precursor cells from human bone marrow (1996) (380)
- Human degenerative valve disease is associated with up-regulation of low-density lipoprotein receptor-related protein 5 receptor-mediated bone formation. (2006) (376)
- Atorvastatin Inhibits Hypercholesterolemia-Induced Cellular Proliferation and Bone Matrix Production in the Rabbit Aortic Valve (2002) (357)
- Osteoprotegerin production by human osteoblast lineage cells is stimulated by vitamin D, bone morphogenetic protein-2, and cytokines. (1998) (332)
- Differentiation of Human Marrow Stromal Precursor Cells: Bone Morphogenetic Protein‐2 Increases OSF2/CBFA1, Enhances Osteoblast Commitment, and Inhibits Late Adipocyte Maturation (1999) (298)
- Atorvastatin Inhibits Hypercholesterolemia-Induced Calcification in the Aortic Valves via the Lrp5 Receptor Pathway (2005) (285)
- Identification of a novel TGF-beta-regulated gene encoding a putative zinc finger protein in human osteoblasts. (1995) (275)
- The actions and interactions of sex steroids and growth factors/cytokines on the skeleton. (1999) (256)
- Modulation of Transforming Growth Factor-β Production in Normal Human Osteoblast-Like Cells by 17β-Estradiol and Parathyroid Hormone (1991) (249)
- Changes in Runx2/Cbfa1 Expression and Activity During Osteoblastic Differentiation of Human Bone Marrow Stromal Cells (2003) (237)
- Overexpression of the TGFbeta-regulated zinc finger encoding gene, TIEG, induces apoptosis in pancreatic epithelial cells. (1997) (234)
- Zeolite a increases proliferation, differentiation, and transforming growth factor β production in normal adult human osteoblast‐like cells in vitro (1992) (233)
- Progesterone-binding components of chick oviduct. 3. Chromatin acceptor sites. (1971) (224)
- Interleukin-1beta and tumor necrosis factor-alpha, but not interleukin-6, stimulate osteoprotegerin ligand gene expression in human osteoblastic cells. (1999) (222)
- Effects of immunosuppressants on receptor activator of NF-kappaB ligand and osteoprotegerin production by human osteoblastic and coronary artery smooth muscle cells. (2001) (221)
- The tamoxifen metabolite, endoxifen, is a potent antiestrogen that targets estrogen receptor alpha for degradation in breast cancer cells. (2009) (214)
- Proteins of chromatin in template restriction. I. RNA synthesis in vitro. (1971) (211)
- Mechanisms of Interaction of a Hormone—Receptor Complex with the Genome of a Eukaryotic Target Cell (1972) (209)
- Proteins of chromatin in template restriction. 3. The macromolecules in specific restriction of the chromatin DNA. (1971) (206)
- Human giant cell tumors of the bone (osteoclastomas) are estrogen target cells. (1994) (203)
- The expression of osteoprotegerin and RANK ligand and the support of osteoclast formation by stromal-osteoblast lineage cells is developmentally regulated. (2000) (190)
- Atorvastatin inhibits calcification and enhances nitric oxide synthase production in the hypercholesterolaemic aortic valve (2005) (182)
- The E3 ubiquitin ligase Itch regulates expression of transcription factor Foxp3 and airway inflammation by enhancing the function of transcription factor TIEG1 (2008) (172)
- Production of various cytokines by normal human osteoblast-like cells in response to interleukin-1 beta and tumor necrosis factor-alpha: lack of regulation by 17 beta-estradiol. (1992) (165)
- Estrogen receptor isoform‐specific regulation of endogenous gene expression in human osteoblastic cell lines expressing either ERα or ERβ (2003) (155)
- New concepts in steroid hormone action: transcription factors, proto-oncogenes, and the cascade model for steroid regulation of gene expression. (1992) (149)
- Steroid hormone regulation of nuclear proto-oncogenes. (1993) (146)
- Early effects of oestradiol-17 on the chromatin and activity of the deoxyribonucleic acid-dependent ribonucleic acid polymerases (I and II) of the rat uterus. (1972) (146)
- The Expression of Osteoprotegerin and RANK Ligand and the Support of Osteoclast Formation by Stromal-Osteoblast Lineage Cells Is Developmentally Regulated* *This work was supported by Grant AG-04875 from the National Institute on Aging. (2000) (145)
- Progesterone-binding components of chick oviduct. V. Exchange of progesterone-binding capacity from target to nontarget tissue chromatins. (1972) (138)
- Androgens regulate bone resorption activity of isolated osteoclasts in vitro. (1999) (137)
- Isolation and characterization of the estrogen receptor in human skin. (1980) (137)
- Calcified Rheumatic Valve Neoangiogenesis Is Associated With Vascular Endothelial Growth Factor Expression and Osteoblast-Like Bone Formation (2005) (135)
- Estrogen regulation of human osteoblastic cell proliferation and differentiation. (1997) (132)
- Estrogen receptor α and β heterodimers exert unique effects on estrogen- and tamoxifen- dependent gene expression in human U2OS osteosarcoma cells (2005) (132)
- Coprescription of tamoxifen and medications that inhibit CYP2D6. (2010) (129)
- Estrogen inhibits interleukin‐6 production and gene expression in a human osteoblastic cell line with high levels of estrogen receptors (1996) (129)
- Development and Characterization of Conditionally Immortalized Osteoblast Precursor Cell Lines from Human Bone Marrow Stroma (1998) (128)
- TGFβ inducible early gene enhances TGFβ/Smad-dependent transcriptional responses (2002) (128)
- Tissue differences in antigenic properties of non-histone protein-DNA complexes. (1971) (128)
- TIEG1 Null Mouse-Derived Osteoblasts Are Defective in Mineralization and in Support of Osteoclast Differentiation In Vitro (2005) (124)
- Estrogen inhibition of periosteal bone formation in rat long bones: down-regulation of gene expression for bone matrix proteins. (1990) (123)
- High-performance capillary electrophoresis of glycoproteins: the use of modifiers of electroosmotic flow for analysis of microheterogeneity. (1992) (121)
- Glucocorticoid-induced activation of latent transforming growth factor-beta by normal human osteoblast-like cells. (1993) (115)
- Lack of a direct effect of estrogen on proliferation and differentiation of normal human osteoblast‐like cells (1991) (112)
- Glucocorticoid regulation of alkaline phosphatase, osteocalcin, and proto‐oncogenes in normal human osteoblast‐like cells (1992) (107)
- Phytoestrogen genistein acts as an estrogen agonist on human osteoblastic cells through estrogen receptors α and β (2003) (107)
- Isolation and quantitation of endogenous vitamin D and its physiologically important metabolites in human plasma by high pressure liquid chromatography. (1977) (107)
- Further characterization of human fetal osteoblastic hFOB 1.19 and hFOB/ERα cells: Bone formation in vivo and karyotype analysis using multicolor fluorescent in situ hybridization (2002) (106)
- Identification of breast cancer cell line-derived paracrine factors that stimulate osteoclast activity. (1999) (104)
- Expression of estrogen receptor isoforms α and β messenger RNA in vaginal tissue of premenopausal and postmenopausal women (2001) (104)
- Deoxyribonucleoproteins and the tissue-specific restriction of the deoxyribonucleic acid in chromatin. (1970) (103)
- Bone morphogenetic protein-6 production in human osteoblastic cell lines. Selective regulation by estrogen. (1998) (99)
- TGFbeta inducible early gene enhances TGFbeta/Smad-dependent transcriptional responses. (2002) (98)
- Evidence for interleukin‐1β production by cultured normal human osteoblast‐like cells (1991) (98)
- Oestrogen effects on osteoblasts and osteoclasts. (1993) (98)
- Krüppel-Like Factor KLF10 Is a Link between the Circadian Clock and Metabolism in Liver (2010) (94)
- Mechanism of action of estrogen on intramembranous bone formation: regulation of osteoblast differentiation and activity. (1992) (92)
- Seasonal changes in the molecular species and nuclear binding of the chick oviduct progesterone receptor. (1979) (91)
- Tissue, cell type, and breast cancer stage‐specific expression of a TGF‐β inducible early transcription factor gene (1998) (91)
- Functional role of KLF10 in multiple disease processes (2010) (91)
- Ovarian steroid action on gene expression: mechanisms and models. (1989) (91)
- Development and characterization of a rapidly proliferating, well‐differentiated cell line derived from normal adult human osteoblast‐like cells transfected with SV40 large T antigen (1992) (86)
- Kruppel-like Factor KLF10 Targets Transforming Growth Factor-β1 to Regulate CD4+CD25− T Cells and T Regulatory Cells* (2009) (84)
- Capillary electrophoresis: a powerful microanalytical technique for biologically active molecules. (1993) (84)
- Molecular and cellular mechanisms of estrogen action on the skeleton (1999) (83)
- Primer on medical genomics. Part III: Microarray experiments and data analysis. (2002) (82)
- 15‐hydroxy‐eicosatetraenoic acid arrests growth of colorectal cancer cells via a peroxisome proliferator‐activated receptor gamma‐dependent pathway (2003) (81)
- Role of specific chromosomal proteins and DNA sequences in the nuclear binding sites for steroid receptors. (1983) (81)
- Estrogen receptor isoform-specific regulation of endogenous gene expression in human osteoblastic cell lines expressing either ERalpha or ERbeta. (2003) (81)
- Soluble complexes between steroid hormones and target-tissue receptors bind specifically to target-tissue chromatin. (1971) (79)
- Estrogen regulation of human osteoblast function is determined by the stage of differentiation and the estrogen receptor isoform (2001) (78)
- Co-stimulation of the Bone-related Runx2 P1 Promoter in Mesenchymal Cells by SP1 and ETS Transcription Factors at Polymorphic Purine-rich DNA Sequences (Y-repeats)* (2009) (78)
- Dose-response of estrogen on bone versus the uterus in ovariectomized mice. (2004) (76)
- Estrogen receptor alpha and beta heterodimers exert unique effects on estrogen- and tamoxifen-dependent gene expression in human U2OS osteosarcoma cells. (2005) (76)
- Role of TIEG1 in biological processes and disease states (2007) (74)
- Estrogen modulation of avian osteoclast lysosomal gene expression. (1993) (72)
- Effects of loss of steroid receptor coactivator-1 on the skeletal response to estrogen in mice. (2004) (72)
- Chromatin of the developing chick oviduct: changes in the acidic proteins. (1973) (72)
- Estrogen receptor-beta sensitizes breast cancer cells to the anti-estrogenic actions of endoxifen (2011) (71)
- Modulation of Transforming Growth Factor β (TGFβ)/Smad Transcriptional Responses through Targeted Degradation of TGFβ-inducible Early Gene-1 by Human Seven in Absentia Homologue* (2002) (71)
- Estrogen Effects on Insulin-Like Growth Factor Gene Expression in a Human Osteoblastic Cell Line with High Levels of Estrogen Receptor (1998) (71)
- Differential Gene Expression of TGFβ Inducible Early Gene (TIEG), Smad7, Smad2 and Bard1 in Normal and Malignant Breast Tissue (2004) (71)
- Transcriptional regulation of Smad2 is required for enhancement of TGFβ/Smad signaling by TGFβ inducible early gene (2002) (70)
- Regulation of c-fos expression and TGF-β production by gonadal and adrenal androgens in normal human osteoblastic cells (1995) (68)
- Spaceflight results in reduced mRNA levels for tissue-specific proteins in the musculoskeletal system. (1994) (66)
- TGFbeta inducible early gene-1 knockout mice display defects in bone strength and microarchitecture. (2006) (65)
- Nuclear binding of progesterone in hen oviduct. Binding to multiple sites in vitro. (1976) (64)
- Cytokine production in the bone marrow microenvironment: failure to demonstrate estrogen regulation in early postmenopausal women. (1996) (64)
- Estrogen and progesterone receptors in meningiomas: comparison of nuclear binding, dextran-coated charcoal, and immunoperoxidase staining assays. (1989) (64)
- Nuclear binding of progesterone in hen oviduct. Role of acidic chromatin proteins in high-affinity binding. (1976) (64)
- Hypercholesterolemic aortic-valve disease. (2003) (63)
- Pulmonary lymphangiomyomatosis: with particular reference to steroid-receptor assay studies and pathologic correlation. (1984) (63)
- Modulation of transforming growth factor-beta production in normal human osteoblast-like cells by 17 beta-estradiol and parathyroid hormone. (1991) (62)
- Estrogen response in the hFOB 1.19 human fetal osteoblastic cell line stably transfected with the human estrogen receptor gene (1995) (60)
- Proteins of chromatin in template restriction. II. Specificity of RNA synthesis. (1971) (59)
- Nonfunctioning progesterone receptors in the developed oviducts from estrogen-withdrawn immature chicks and in aged nonlaying hens. (1982) (59)
- The effects of acidic proteins and RNA on the histone inhibition of the DNA-dependent RNA synthesis in vitro. (1969) (57)
- Normal human osteoblast‐like cells consistently express genes for insulin‐like growth factors I and II but transformed human osteoblast cell lines do not (1995) (55)
- Steroid action on gene expression: possible roles of regulatory genes and nuclear acceptor sites. (1989) (54)
- Potential mechanism of estrogen-mediated decrease in bone formation: estrogen increases production of inhibitory insulin-like growth factor-binding protein-4. (1996) (54)
- Circannual rhythms in steroid receptor concentration and nuclear binding in the chick oviduct. (1980) (54)
- Nuclear binding of progesterone in chick oviduct. Multiple binding sites in vivo and transcriptional response. (1976) (53)
- Correlation between mRNA levels for bone cell proteins and bone formation in long bones of maturing rats. (1991) (53)
- ERβ1: characterization, prognosis, and evaluation of treatment strategies in ERα-positive and -negative breast cancer (2014) (53)
- Effects of orbital spaceflight on human osteoblastic cell physiology and gene expression. (2000) (53)
- Response of Bipotential Human Marrow Stromal Cells to Insulin-Like Growth Factors: Effect on Binding Protein Production, Proliferation, and Commitment to Osteoblasts and Adipocytes1. (1999) (52)
- Overexpression of the TGF-β antagonist Smad7 in endometrial cancer (2005) (52)
- Estrogen‐TGFβ cross‐talk in bone and other cell types: Role of TIEG, Runx2, and other transcription factors (2008) (52)
- Aspects of chromosomal structure. I. Circular dichroism studies. (1971) (51)
- TIEG-null mice display an osteopenic gender-specific phenotype. (2008) (51)
- 2-methoxyestradiol induces interferon gene expression and apoptosis in osteosarcoma cells. (2002) (51)
- Distinct mechanisms of bisphosphonate action between osteoblasts and breast cancer cells: identity of a potent new bisphosphonate analogue (2002) (50)
- Estrogen Regulation of a Transforming Growth Factor-β Inducible Early Gene That Inhibits Deoxyribonucleic Acid Synthesis in Human Osteoblasts. (1998) (50)
- Estrogen receptor beta isoform-specific induction of transforming growth factor beta-inducible early gene-1 in human osteoblast cells: an essential role for the activation function 1 domain. (2008) (50)
- Structure studies on chromatin and nucleohistones. Thermal denaturation profiles recorded in the presence of urea. (1971) (49)
- A nuclear binding assay to assess the biological activity of steroid receptors in isolated animal and human tissues. (1987) (49)
- Osteoclasts and transforming growth factor-beta: estrogen-mediated isoform-specific regulation of production. (1996) (49)
- Expression of estrogen receptor isoforms alpha and beta messenger RNA in vaginal tissue of premenopausal and postmenopausal women. (2001) (49)
- Analysis of the molecular species of the chick oviduct progesterone receptor using isoelectric focusing. (1979) (48)
- Development, characterization, and applications of a novel estrogen receptor beta monoclonal antibody (2012) (48)
- Rcl is a novel ETV1/ER81 target gene upregulated in breast tumors (2008) (48)
- Rapid isolation of total acidic proteins from chromatin of various chick tissues. (1973) (48)
- Nuclear binding of estrogen-receptor complex: receptor-specific nuclear acceptor sites. (1982) (47)
- α,ω-Bis-quaternary ammonium alkanes as effective buffer additives for enhanced capillary electrophoretic separation of glycoproteins (1994) (47)
- TGF-β1 signaling and Krüppel-like factor 10 regulate bone marrow-derived proangiogenic cell differentiation, function, and neovascularization. (2011) (47)
- Factors affecting the binding of chick oviduct progesterone receptor to deoxyribonucleic acid: evidence that deoxyribonucleic acid alone is not the nuclear acceptor site. (1980) (47)
- Histone demethylase JARID1B/KDM5B is a corepressor of TIEG1/KLF10. (2010) (47)
- Regulation of nuclear binding of the avian oviduct progesterone receptor. Changes during estrogen-induced oviduct development, withdrawal, and secondary stimulation. (1984) (46)
- Mutual antagonism of estrogen receptors alpha and beta and their preferred interactions with steroid receptor coactivators in human osteoblastic cell lines. (2003) (46)
- Transcriptional regulation of Smad2 is required for enhancement of TGFbeta/Smad signaling by TGFbeta inducible early gene. (2002) (46)
- Modulation of transforming growth factor beta (TGFbeta)/Smad transcriptional responses through targeted degradation of TGFbeta-inducible early gene-1 by human seven in absentia homologue. (2002) (45)
- Rapid regulation of c-myc protooncogene expression by progesterone in the avian oviduct. (1988) (45)
- Phytoestrogen genistein acts as an estrogen agonist on human osteoblastic cells through estrogen receptors alpha and beta. (2003) (45)
- Effect of TGF‐β inducible early gene deficiency on flexor tendon healing (2006) (45)
- Estrogen Receptor Isoform‐Specific Induction of Progesterone Receptors in Human Osteoblasts (2002) (44)
- Effects of estrogen and progesterone on transcription, chromatin and ovalbumin gene expression in the chick oviduct. (1976) (44)
- Regulation of osteoblastic phenotype and gene expression by hop-derived phytoestrogens (2005) (44)
- Visualization of nonfunctioning adrenal adenomas with iodocholesterol: possible relationship to subcellular distribution of tracer. (1978) (43)
- Specific methods for the isolation of nuclei from chick oviduct. (1974) (43)
- Response of bipotential human marrow stromal cells to insulin-like growth factors: effect on binding protein production, proliferation, and commitment to osteoblasts and adipocytes. (1999) (42)
- Feedback regulation of vitamin D metabolism by 1,25-dihydroxycholecalciferol. (1977) (42)
- Progesterone binding to hen oviduct genome: specific versus nonspecific binding. (1976) (42)
- TGF-β Inducible Early Gene 1 Regulates Osteoclast Differentiation and Survival by Mediating the NFATc1, AKT, and MEK/ERK Signaling Pathways (2011) (41)
- Noncanonical K27-Linked Polyubiquitination of TIEG1 Regulates Foxp3 Expression and Tumor Growth (2011) (41)
- Mammalian RNA polymerases I and II: independent diurnal variations in activity. (1972) (40)
- TIEG1/KLF10 Modulates Runx2 Expression and Activity in Osteoblasts (2011) (39)
- Cytokine‐specific induction of the TGF‐β inducible early gene (TIEG): Regulation by specific members of the TGF‐β family (2000) (39)
- Role of nuclear proteins as high affinity sites ("acceptors") for progesterone in the avian oviduct. (1976) (39)
- Endoxifen’s Molecular Mechanisms of Action Are Concentration Dependent and Different than That of Other Anti-Estrogens (2013) (39)
- Isolation and characterization of the estrogen receptor in hen oviduct: evidence for two molecular species. (1980) (39)
- Acceptor sites for the oestrogen receptor in hen oviduct chromatin. (1983) (38)
- The Dose‐Response Effects of Ethanol on the Human Fetal Osteoblastic Cell Line (2001) (38)
- A promising approach for treatment of tumor-induced bone diseases: utilizing bisphosphonate derivatives of nucleoside antimetabolites. (2010) (38)
- Nuclear matrix localization and specific matrix DNA binding by receptor binding factor 1 of the avian oviduct progesterone receptor. (1991) (38)
- Reconstitution of nativelike nuclear acceptor sites of the avian oviduct progesterone receptor: evidence for involvement of specific chromatin proteins and specific DNA sequences. (1984) (38)
- Bone growth and turnover in progesterone receptor knockout mice. (2008) (35)
- 17beta-estradiol-dependent activation of signal transducer and activator of transcription-1 in human fetal osteoblasts is dependent on Src kinase activity. (2005) (35)
- Tissue specific binding in vitro of progesterone-receptor to the chromatins of chick tissues. (1971) (35)
- COMPARISON AND CHARACTERIZATION OF NUCLEAR ISOLATION PROCEDURES AS APPLIED TO CHICK OVIDUCT (1973) (34)
- A rapid method for analysis of ligand binding to deoxyribonucleic acid and soluble nucleoproteins using streptomycin: application to steroid receptor ligands. (1983) (34)
- Direct Action of Naturally Occurring Estrogen Metabolites on Human Osteoblastic Cells (2000) (34)
- Evidence of steroid receptors in human osteoblast-like cells. (1989) (34)
- Zeolite a inhibits osteoclast‐mediated bone resorption in vitro (1995) (33)
- Rapid induction of the c-jun protooncogene in the avian oviduct by the antiestrogen tamoxifen. (1991) (33)
- Estrogen receptor alpha/beta isoforms, but not betacx, modulate unique patterns of gene expression and cell proliferation in Hs578T cells. (2007) (32)
- Effect of TGF-beta inducible early gene deficiency on flexor tendon healing. (2006) (32)
- Changes in chromatin composition and hormone binding during chick oviduct development. (1971) (32)
- Characterization of the glucocorticoid receptor in human skin. (1983) (32)
- Overexpression of the TGF-beta antagonist Smad7 in endometrial cancer. (2005) (32)
- Estrogen regulation of a transforming growth factor-beta inducible early gene that inhibits deoxyribonucleic acid synthesis in human osteoblasts. (1998) (32)
- Age-dependent changes in the mechanical properties of tail tendons in TGF-β inducible early gene-1 knockout mice (2006) (31)
- Failure of isolated rat tibial periosteal cells to 5α reduce testosterone to 5α‐dihydrotestosterone (1990) (31)
- Atorvastatin decreases cellular proliferation and bone matrix expression in the hypercholesterolemic mitral valve. (2005) (31)
- Estrogen regulation of the biological activity of the avian oviduct progesterone receptor and its ability to induce avidin. (1986) (30)
- Mechanisms of estrogen action on bone. (1989) (30)
- Nuclear Binding Sites (“Acceptors”) for Progesterone in Avian Oviduct: Characterization of the Highest‐Affinity Sites * (1977) (30)
- Primer on medical genomics part II: Background principles and methods in molecular genetics. (2002) (29)
- Effects of loss of classical estrogen response element signaling on bone in male mice. (2007) (29)
- Binding of polycyclic aromatic hydrocarbons to transcriptionally active nuclear subfractions of AKR mouse embryo cells. (1976) (29)
- Hormone-receptor interactions with the genome of eucaryotic target cells. (1973) (28)
- TGFβ-Inducible Early Gene (TIEG) Also Codes for Early Growth Response α (EGRα): Evidence of Multiple Transcripts from Alternate Promoters ☆ (1998) (28)
- Rapid inhibition of the c-jun proto-oncogene expression in avian oviduct by estrogen. (1990) (28)
- Distribution of estrogen receptors α and β mRNA in mouse urogenital tissues and their expression after oophorectomy and estrogen replacement (2003) (28)
- Studies on the RNA polymerase-histone complexes. (1969) (27)
- Estrogen Receptor Isoform-specific Regulation of the Retinoblastoma-binding Protein 1 (RBBP1) Gene (2006) (26)
- Skeletal Consequences of Deletion of Steroid Receptor Coactivator-2/Transcription Intermediary Factor-2* (2009) (26)
- Cytokine-specific induction of the TGF-beta inducible early gene (TIEG): regulation by specific members of the TGF-beta family. (2000) (26)
- Support for chromatin acidic proteins as acceptors for progesterone in the chick oviduct. (1979) (26)
- Partial purification of the Epstein-Barr virus nuclear antigen(s). (1983) (26)
- TGFbeta inducible early gene-1 directly binds to, and represses, the OPG promoter in osteoblasts. (2010) (25)
- Klf10 inhibits IL‐12p40 production in macrophage colony‐stimulating factor‐induced mouse bone marrow‐derived macrophages (2013) (25)
- Multiple-buffer-additive strategies for enhanced capillary electrophoretic separation of peptides. (1994) (25)
- The skeletal response to estrogen is impaired in female but not in male steroid receptor coactivator (SRC)-1 knock out mice. (2008) (24)
- Comparison of estrogen receptors in human premenopausal and postmenopausal uteri: indication of biologically inactive receptor in postmenopausal uteri. (1982) (24)
- P2X(3) receptor subunit messenger RNA expression in the female mouse bladder after oophorectomy with or without estrogen replacement. (2002) (21)
- Microassay for nuclear binding of steroid receptors with use of intact cells from small samples of avian and human tissue. (1988) (21)
- Primer on medical genomics. Part IV: Expression proteomics. (2002) (21)
- Rapid down-regulation of c-jun protooncogene transcription by progesterone in the avian oviduct. (1993) (20)
- Growth hormone and drug metabolism. Acute effects on microsomal mixed-function oxidase activities in rat liver. (1976) (20)
- Characterization of a purified chromatin acceptor protein (receptor binding factor 1) for the avian oviduct progesterone receptor. (1991) (20)
- Nuclease resistance and the enrichment of native nuclear acceptor sites for the avian oviduct progesterone receptor. (1986) (19)
- Updates and New Models for Steroid Hormone Action (1991) (19)
- Loss of ERE binding activity by estrogen receptor‐α alters basal and estrogen‐stimulated bone‐related gene expression by osteoblastic cells (2008) (19)
- CHAPTER 6 – Chemical Characterization of Nuclear Acceptors for the Avian Progesterone Receptor (1982) (19)
- Retinoblastoma binding protein-1 (RBP1) is a Runx2 coactivator and promotes osteoblastic differentiation (2010) (19)
- Relationship between DNA ploidy and functional estrogen receptors in operable prostate cancer. (1997) (18)
- Evidence for an androgen receptor in the human placenta. (1981) (18)
- mRNA Transcription linked to the Morphological and Plasma Membrane Changes induced by Cyclic AMP in Tumour Cells (1973) (18)
- Age-dependent changes in the mechanical properties of tail tendons in TGF-beta inducible early gene-1 knockout mice. (2006) (18)
- Steroid and Sterol Hormone Action (2011) (18)
- Evidence for specific DNA sequences in the nuclear acceptor sites of the avian oviduct progesterone receptor. (1985) (18)
- Nuclear matrix and steroid hormone action. (1999) (17)
- Nuclear acceptor sites for steroid hormone receptors: comparisons of steroids and antisteroids. (1988) (17)
- Monoclonal antibodies recognizing the nuclear binding sites of the avian oviduct progesterone receptor. (1986) (17)
- A Specific Oviduct Target-Tissue Receptor For Progesterone: Identification, Characterization, Partial Purification, Inter-Compartmental Transfer Kinetics and Specific Interaction with the Genome (1971) (17)
- Two-step "hot" PCR amplification of GC-rich avian c-myc sequences. (1993) (17)
- Rapid inhibition of c-myc gene expression by a glucocorticoid in the avian oviduct. (1989) (17)
- Utility of high resolution capillary electrophoresis for monitoring peptide homo- and hetero-dimer formation. (1993) (16)
- Absence of high-affinity binding of progesterone (R 5020) in human placenta and fetal membranes. (1981) (16)
- The proto-oncogene c-fms is overexpressed in endometrial cancer. (1993) (16)
- Glucocorticoid receptor in human placenta: studies of concentration and functional differences of preterm and term tissue. (1983) (16)
- Estrogens and Progestins (2008) (15)
- Nuclear acceptor sites for sex steroid hormone receptors in chromatin. (1987) (15)
- The interaction of RNA polymerase with histones. (1969) (15)
- High-performance capillary electrophoretic analysis of chloramphenicol acetyl transferase activity. (1992) (15)
- The TGFβ inducible early gene plays a central role in the anti-proliferative response to TGFβ (2004) (14)
- Isolation and electrophoresis of nuclear proteins of bean (1968) (14)
- Tissue-specific expression of bone proteins in femora of growing rats. (1992) (14)
- Histone Biosynthesis and the Cell Cycle (1971) (14)
- Overview of estrogen action in osteoblasts: role of the ligand, the receptor, and the co-regulators. (2003) (14)
- A distinction between 3-methylcholanthrene and estrogen binding in the uterus. (1972) (14)
- Molecular structure of tail tendon fibers in TIEG1 knockout mice using synchrotron diffraction technology. (2010) (14)
- TGFbeta-inducible early gene (TIEG) also codes for early growth response alpha (EGRalpha): evidence of multiple transcripts from alternate promoters. (1998) (14)
- Steroid receptor binding to nuclei: effect of assay conditions on the integrity of chromatin. (1979) (13)
- 2‐methoxyestradiol‐mediated anti‐tumor effect increases osteoprotegrin expression in osteosarcoma cells (2010) (13)
- Isolation and characterization of the nuclear acceptor that binds the progesterone-receptor complex in hen oviduct. (1977) (13)
- Isolation and analysis of the proteins of plant nuclei from two stages of differentiation of Phaseolus vulgaris (1970) (13)
- Distribution of estrogen receptors alpha and beta mRNA in mouse urogenital tissues and their expression after oophorectomy and estrogen replacement. (2003) (13)
- The proto‐oncogene c‐fms is overexpressed in endometrial cancer (1994) (13)
- 9 – The Role of Nuclear Acidic Proteins in Binding Steroid Hormones (1974) (13)
- Reproducibility of sample separation using liquid or forced air convection thermostatted high performance capillary electrophoresis systems (1992) (12)
- Proteins that mask the nuclear binding sites of the avian oviduct progesterone receptor. (1985) (12)
- Evidence for two classes of chromatin-associated Epstein-Barr virus-determined nuclear antigen (1982) (12)
- Interactions of the nuclear matrix-associated steroid receptor binding factor with its DNA binding element in the c-myc gene promoter. (2000) (12)
- Mutual antagonism of estrogen receptors (cid:1) and (cid:2) and their preferred interactions with steroid receptor coactivators in human osteoblastic cell lines (2003) (12)
- Binding of chemical carcinogens in the lung. (1974) (11)
- Nuclear matrix acceptor binding sites for steroid hormone receptors: a candidate nuclear matrix acceptor protein. (1995) (11)
- Bone marrow stromal cells express two distinct splice variants of ER‐α that are regulated by estrogen (2005) (11)
- Problems and artifacts in the identification of nuclear acceptor sites for the avian oviduct progesterone receptor. (1985) (11)
- A nuclear matrix acceptor site for the progesterone receptor in the avian c-myc gene promoter. (1996) (11)
- Separation and characterization of transcriptionally active and inactive nuclear subfractions of AKR mouse embryo cells. (1976) (11)
- MULTIPLE BINDING SITES FOR PROGESTERONE IN THE HEN OVIDUCT NUCLEUS: EVIDENCE THAT ACIDIC PROTEINS REPRESENT THE ACCEPTORS (1975) (11)
- Procalcitonin NH2‐terminal cleavage peptide has no mitogenic effect on normal human osteoblast‐like cells (1991) (10)
- Androgen receptor in human foreskin: II. Characterization of the receptor from hypospadiac tissue (1983) (10)
- Effects of stable transfection of human fetal osteoblast cells with estrogen receptor-alpha on regulation of gene expression by tibolone. (2006) (10)
- Methods for isolation and characterization of acidic chromatin proteins. (1975) (10)
- Fractionation of chromosomal nonhistone proteins using chromatin--cellulose resins: purification of steroid hormone acceptor proteins. (1978) (9)
- WOUND-HEALING PROPERTIES OF TRANSFORMING GROWTH FACTOR β (TGF-β) INDUCIBLE EARLY GENE 1 (TIEG1) KNOCKOUT MICE. (2008) (9)
- Androgen insensitivity syndrome: gonadal androgen receptor activity. (1984) (9)
- Characterization of the chromatin acceptor sites for the avian oviduct progesterone receptor using monoclonal antibodies. (1987) (9)
- Steroid receptors and giant cell tumor of bone. (1989) (9)
- Characterization of Epstein-Barr virus nuclear antigen(s) in different cell lines by radioimmunoelectrophoresis. (1984) (9)
- Partial purification and preparation of polyclonal antibodies against candidate chromatin acceptor proteins for the avian oviduct progesterone receptor. (1988) (9)
- Echistatin, a potential new drug for osteoporosis. (1993) (8)
- General mechanisms of steroid receptors and receptor coregulator action (2004) (8)
- Human Osteoblast-Like Cells Express Aromatase Immunoreactivity (1994) (8)
- A NEW MODEL FOR STEROID REGULATION OF GENE TRANSCRIPTION USING CHROMATIN ACCEPTOR SITES AND REGULATORY GENES AND THEIR PRODUCTS (1987) (8)
- Hormonal control of oviduct growth and differentiation. (1974) (8)
- Endoxifen, but not 4-hydroxytamoxifen, degrades the estrogen receptor in breast cancer cells: a differential mechanism of action potentially explaining CYP2D6 effect. (2009) (8)
- Auxin-induced Elimination of a Protein in Bean Hypocotyl (1967) (8)
- Covalent binding of benzo[a]pyrene metabolites to DNA, RNA and chromatin proteins in the AKR mouse embryo cell-line. (1981) (8)
- Growth hormone and drug metabolism. Acute effects on nuclear ribonucleic acid polymerase activity and chromatin. (1976) (8)
- The binding of benzo(a)pyrene and N‐methyl‐N′‐nitro‐n‐nitrosoguanidine to subnuclear fractions of akr mouse embryo cells in culture (1977) (8)
- A nuclear binding assay for measurement of biologically active androgen receptors in animal tissues and human prostate cancer. (1988) (7)
- A Case for Estrogen Receptors on Cell Membranes and Nongenomic Actions of Estrogen (2003) (7)
- Mitral valve disease in a patient with familial hypercholesterolemia. (2010) (7)
- Indoleacetic Acid and Molecular Differentiation Evidence for Interaction (1967) (7)
- Identification of biologically active and inactive steroid receptors. (1980) (7)
- Isolation and analysis of the proteins of plant nuclei: interaction of hormones with nuclear proteins in isolated nuclei of Phaseolus vulgaris. (1970) (7)
- Competitive binding and metabolism of several carcinogenic polycyclic aromatic hydrocarbons by AKR mouse embryo cells in culture. (1978) (7)
- Effects of metabolism on the binding of polycyclic hydrocarbons to nuclear subfractions of cultured AKR mouse embryo cells. (1977) (7)
- TIEG1-NULL OSTEOCYTES DISPLAY DEFECTS IN THEIR MORPHOLOGY, DENSITY AND SURROUNDING BONE MATRIX. (2009) (7)
- Chapter 37 – Estrogens and Progestins (2002) (6)
- CHAPTER 19 – Sex Steroid Effects on Bone Metabolism (2006) (6)
- TIEG1-null tenocytes display age-dependent differences in their gene expression, adhesion, spreading and proliferation properties. (2011) (6)
- TGF-beta regulation of nuclear proto-oncogenes and TGF-beta gene expression in normal human osteoblast-like cells. (1995) (6)
- Kruppel-like factor 10 protects against acute viral myocarditis by negatively regulating cardiac MCP-1 expression (2020) (6)
- The Effects of a Novel Hormonal Breast Cancer Therapy, Endoxifen, on the Mouse Skeleton (2014) (6)
- The isolation of large quantities of undamaged cellular organelles and cytosolic enzymes using a low-shear continuous tissue homogenizer. (1984) (6)
- Evidence for an androgen receptor in human testis. (1984) (5)
- Evidence for a glucocorticoid receptor in human skin (1981) (5)
- Enrichment of a second class of native acceptor sites for the avian oviduct progesterone receptor as intact chromatin fragments. (1991) (5)
- Failure of isolated rat tibial periosteal cells to 5 alpha reduce testosterone to 5 alpha-dihydrotestosterone. (1990) (5)
- The Basic Biology of Estrogen and Bone (2003) (5)
- Bone marrow stromal cells express two distinct splice variants of ER-alpha that are regulated by estrogen. (2005) (5)
- Identification of putative nonfunctional steroid receptors in breast and endometrial cancer. (1990) (4)
- Characterization of the Nuclear Binding Sites (Acceptor Sites) for a Steroid Receptor (1987) (4)
- Commercial capillary electrophoresis instrumentation (1994) (4)
- The androgen receptor in normal human foreskin. I. Stabilization and identification of two receptor subunits. (1985) (4)
- Editorial: Echistatin, a potential new drug for osteoporosis (1993) (3)
- Porphyria-inducing drugs: comparative effects on nuclear ribonucleic acid polymerases in rat liver. (1976) (3)
- The Placenta as a Target Tissue for Steroids (1984) (3)
- Androgen receptor in human foreskin. II. Characterization of the receptor from hypospadiac tissue. (1984) (3)
- Isolation of the Epstein-Barr virus nuclear antigen from chromatin preparations. (1978) (3)
- Atorvastatin inhibits aortic valve calcification in an experimental model of chronic hypercholesterolemia via nonlipid lowering effects (2003) (3)
- Circannual rhythms in progesterone receptor levels and functions. (1979) (3)
- Identification and characterization of human skin estrogen receptors (1979) (3)
- Dissociation of RNA-histone complexes by DNA (1970) (3)
- Abstract PD05-11: Development, Characterization, and EffectiveIn VitroTreatment of an Endoxifen Resistant Breast Cancer Cell Line (2010) (2)
- Primer on medical genomics. The end of the beginning. (2004) (2)
- The androgen receptor in normal human foreskin (1985) (2)
- The interaction and effects of chemical carcinogens on rat organ chromatin (1974) (2)
- The classical estrogen receptor transcriptional pathway (2006) (2)
- AW-1 Aortic Valve Calcification Is Accompanied By A Transition To An Osteoblast Phenotype (2002) (2)
- The Impact of Estrogen Receptor-beta on the Actions of Endoxifen in Breast Cancer Cells. (2009) (2)
- Binding of [3H]benzo(a)pyrene metabolites to the AKR mouse embryo cell line nuclear proteins. (1981) (2)
- Steroid receptors at the nexus of transcriptional regulation. (1998) (1)
- In Vitro Cell Culture Model of Calcification: Molecular Regulation of Myofibroblast Differentiation to an Osteoblast Phenotype (2014) (1)
- Immortalized Osteoblast Cell Systems (New Human Fetal Osteoblast Systems) (2014) (1)
- Subject Index, Vol. 22, 1984 (1984) (1)
- Structural alterations of acidic proteins by acid treatment of chromatin (1973) (1)
- ASBMR 27th Annual Meeting SU001–SU527 (2011) (1)
- Inhibition of RNA polymerase activity by arginine-rich histones (1969) (1)
- [Characterization of nuclear acceptor sites for the progesterone receptor of the chick oviduct (author's transl)]. (1982) (1)
- Human Bone Cells: Newly Discovered Target Cells for Sex Steroids (1994) (1)
- Novel regulations in steroid action: role of receptor subunits and chromosomal proteins in nuclear binding (1981) (1)
- Evidence for DNA sequence specificity of the acceptor protein which is bound by the progesterone receptor (1979) (1)
- Characterization of a binding protein which is specific, saturable and of high affinity for the carcinogen, benzo(a)pyrene (1981) (1)
- Hormones and Transcriptional Activity of Chromatin (1974) (1)
- ERβ1: characterization, prognosis, and evaluation of treatment strategies in ERα-positive and -negative breast cancer (2014) (1)
- Tumor Growth of TIEG1 Regulates Foxp3 Expression and Noncanonical K27-Linked Polyubiquitination (2011) (1)
- Synergistic regulation of the Runx2 P1 promoter in mesenchymal cells by a conserved HLH box and purine‐rich elements (GAY motifs) (2008) (1)
- 79 Specific proteins and DNA sequences as nuclear binding sites for the avian oviduct progesterone receptor (1983) (0)
- 94 A nuclear binding assay to detect steroid responsive tumors (1983) (0)
- Abstract 5685: TGF-beta Signaling and Kruppel-like Factor 10 Regulate Bone Marrow-derived EPC Differentiation, Function, and Neovascularization (2009) (0)
- A biopsy nuclear binding assay to predict responses of human cancers to steroid therapy (1985) (0)
- Comparison of tendon fiber structures between wild type and TIEG knockout mice using synchrotron microdiffraction (2008) (0)
- Evidence that nonhistone chromosomal proteins mask nuclear binding sites for the progesterone receptor (1979) (0)
- Monoclonal antibodies against putative nuclear acceptor sites of the avian oviduct progesterone receptor. (1984) (0)
- 60 DEGENERATIVE VERSUS RHEUMATIC MITRAL VALVE DISEASE: A COMPARISON OF CELLULAR PROLIFERATION AND OSTEOBLAST MEDIATED EXTRACELLULAR MATRIX PRODUCTION (2005) (0)
- 217. Chromatin binding site for progesterone in the hen oviduct (1974) (0)
- Factors That Stimulate Osteoclast Activity Identification of Breast Cancer Cell Line-derived Paracrine Updated (1999) (0)
- Soluble Complexes between Steroid HormonesandTarget-Tissue Receptors BindSpecifically toTarget-Tissue Chromatin (dihydrotestosterone-prostate/estradiol-uterus/progesteroneoviduct) (1971) (0)
- Experimental Evidence for the Role of Atherosclerosis in Calcific Aortic Valve Disease (2013) (0)
- articleRetinoblastoma binding protein-1 ( RBP 1 ) is a Runx 2 coactivator and promotes osteoblastic differentiation (2015) (0)
- Abstract A03: Krüppel-like Transcription Factor-10 (KLF10) suppresses the TGFβ-induced epithelial-to-mesenchymal transition (2016) (0)
- P3-16-09: Endoxifen, a Newly Developed Breast Cancer Drug, Has Anabolic Actions on the Mouse Skeleton. (2011) (0)
- Abstract P5-05-01: Endoxifen, a novel breast cancer therapy, elicits unique beneficial effects on bone relative to that of other selective estrogen receptor modulators (2013) (0)
- 59 ATORVASTATIN ATTENUATES LRP5/WNT-MEDIATED ATHEROSCLEROSIS AND OSTEOPOROSIS IN A MOUSE MODEL OF EXPERIMENTAL HYPERCHOLESTEROLEMIA. (2007) (0)
- Immunocharacterization of the Nuclear Acceptor Sites for the Avian Oviduct Progesterone Receptor (1987) (0)
- Kruppel-Like Factor 10 (KLF10)-Deficient Mice Have Marked Defects In EPC Differentiation, Function, and Angiogenesis (2010) (0)
- The regulation of the biological function of steroid-receptors in chickens and humans (1984) (0)
- P4-02-03: Biological Functions of Estrogen Receptor-beta and Its Variants in Breast Cancer. (2011) (0)
- Experimental Model of Aortic Valve Calcification to Induce Osteoblast Differentiation (2014) (0)
- Contents, Vol. 22, 1984 (1984) (0)
- Abstract 673: KLF10 is a Critical Mediator of Wnt Signaling in Aortic Valve Interstitial Cells (2014) (0)
- Lack of an effect of estrogen on endogenous RNA polymerase II in guinea pig brain. (1984) (0)
- The E3 ubiquitin ligase Itch regulates Foxp3 expression and airway inflammation via enhancing TIEG1 function (2008) (0)
- Binding of the chick oviduct progesterone receptor to specific nuclear acceptor sites (1980) (0)
- Determination de l'agressivite du cancer (2003) (0)
- Evidence that human placenta and fetal membranes are not estrogen target tissues (1981) (0)
- In vivo and in vitro biological binding site for progesterone in the oviduct nucleus (1975) (0)
- 1107-135 Neoangiogenesis via vascular endothelial growth factor expression is associated with an osteoblast-like bone formation in calcified rheumatic heart valves (2004) (0)
- Immortalized osteoblast cell systems (new human fetal osteoblast systems). (1995) (0)
- AORTIC VALVE MYOFIBROBLAST CELL UNDERGOES DIFFERENTATION TO AN OSTEOBLAST CELL (2004) (0)
- Aortic Valve Calcification Is Accompanied by a Hypercholesterolemia Induced Osteoblast Phenotype and Is Inhibited by Atorvastatin (2003) (0)
- A rapid, sensitive assay for analyzing defects in metabolism of steroids in normal and diseased human tissues. (1985) (0)
- Inhibition of human osteoblast proliferation and mineralization by breast cancer cell-derived paracrine factors (2001) (0)
- Characterization of Two Forms of the 72,000 MW EBNA and a Cross-Reacting Cellular Protein (1985) (0)
- Binding of [ 3 H ] Benzo ( a ) pyrene Metabolites to the AKR Mouse Embryo Cell Line Nuclear Proteins 1 (2006) (0)
- Abstract P2-09-25: ERα Expression in Breast Cancer: A Conundrum of Antibody Specificity? (2010) (0)
- Abstract P6-04-03: ERb and breast cancer: A potential predictive and prognostic biomarker and novel therapeutic drug target (2013) (0)
- Overexpression of c-fms mRNA in endometrial cancer is associated with poor prognosis indicators (1992) (0)
- Identification ofandrogen receptors innormalhuman osteoblast-like cells (1989) (0)
- Visualization of Nonfunctionin 9 Adrenal Adenomas Possible Relationship to Subcelluiar Distribution of Tracer (2006) (0)
- 1061 Atorvastatin inhibits mitral regurgitation in an experimental hypercholesterolemia rabbit model (2006) (0)
- Abstract 5940: Pttg1 Regulates Cardiac Hypertrophy (2008) (0)
- Role of Nonhistone Chromatin Proteins and Specific DNA Sequences in the Nuclear Binding of Steroid Receptors (2019) (0)
- Kruppel-like Factor KLF10 Targets Transforming Growth Factor-1 to Regulate CD4CD25 T Cells (2009) (0)
- TGFß-Inducible Early Gene-1 (TIEG1): A Novel Hypertrophic Cardiomyopathy- Susceptibility Gene (2010) (0)
- Oestrogen Effects on Osteoblasts (1993) (0)
- A TGF- β /Estrogen-inducible Early Gene (TIEG): A Candidate Tumor Suppressor or Cell Cycle Regulator (2001) (0)
- Tissue differences in antigenic properties of non-histone protein-DNA complexes. (1971) (0)
- mice inducible early gene-1 knockout β tail tendons in TGF- Age-dependent changes in the mechanical properties of (2015) (0)
- Kruppel-Like Factor 10 Protects Against Acute Viral Myocarditis by Negatively Regulating Cardiac MCP-1 Expression to Decrease Inflammatory Monocytes Infiltration (2019) (0)
- Abstract P6-03-06: Therapeutic targeting of ERβ in triple negative breast cancer (2015) (0)
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