Torgeir Flatmark
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(Suggest an Edit or Addition)Torgeir Flatmark's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Characterization of the immature secretory granule, an intermediate in granule biogenesis (1991) (231)
- Recessively inherited L-DOPA-responsive dystonia caused by a point mutation (Q381K) in the tyrosine hydroxylase gene. (1995) (199)
- Recessively inherited L-DOPA-responsive parkinsonism in infancy caused by a point mutation (L205P) in the tyrosine hydroxylase gene. (1996) (181)
- Brown adipose tissue mitochondria. (1975) (180)
- Expression of recombinant human phenylalanine hydroxylase as fusion protein in Escherichia coli circumvents proteolytic degradation by host cell proteases. Isolation and characterization of the wild-type enzyme. (1995) (170)
- Crystal structure of the catalytic domain of human phenylalanine hydroxylase reveals the structural basis for phenylketonuria (1997) (165)
- Structural Insight into the Aromatic Amino Acid Hydroxylases and Their Disease-Related Mutant Forms. (1999) (150)
- The progenitor cell marker NG2/MPG promotes chemoresistance by activation of integrin-dependent PI3K/Akt signaling (2008) (148)
- Catecholamine biosynthesis and physiological regulation in neuroendocrine cells. (2000) (134)
- Selective storage of acetylcholine, but not catecholamines, in neuroendocrine synaptic-like microvesicles of early endosomal origin (1993) (131)
- Enhancement of long-chain acyl-CoA hydrolase activity in peroxisomes and mitochondria of rat liver by peroxisomal proliferators. (1984) (124)
- Crystal structure of the ternary complex of the catalytic domain of human phenylalanine hydroxylase with tetrahydrobiopterin and 3-(2-thienyl)-L-alanine, and its implications for the mechanism of catalysis and substrate activation. (2002) (103)
- Mitochondrial iron not bound in heme and iron-sulfur centers. Estimation, compartmentation and redox state. (1980) (99)
- Energy-dependent accumulation of iron by isolated rat liver mitochondria. Requirement of reducing equivalents and evidence for a unidirectional flux of Fe(II) across the inner membrane. (1975) (99)
- Multiple forms of cytochrome c in the rat. Precursor-product relationship between the main component Cy I and the minor components Cy II and Cy 3 in vivo. (1968) (96)
- Recombinant human tyrosine hydroxylase isozymes. Reconstitution with iron and inhibitory effect of other metal ions. (1991) (95)
- Resonance Raman studies on the blue-green-colored bovine adrenal tyrosine 3-monooxygenase (tyrosine hydroxylase). Evidence that the feedback inhibitors adrenaline and noradrenaline are coordinated to iron. (1988) (94)
- Crystal structure and site-specific mutagenesis of pterin-bound human phenylalanine hydroxylase. (2000) (94)
- High resolution crystal structures of the catalytic domain of human phenylalanine hydroxylase in its catalytically active Fe(II) form and binary complex with tetrahydrobiopterin. (2001) (90)
- Purification and Characterization of Dopamine β ‐Hydroxylase from Bovine Adrenal Medulla (1976) (89)
- Structure/function relationships in human phenylalanine hydroxylase. Effect of terminal deletions on the oligomerization, activation and cooperativity of substrate binding to the enzyme. (1996) (88)
- 2.0A resolution crystal structures of the ternary complexes of human phenylalanine hydroxylase catalytic domain with tetrahydrobiopterin and 3-(2-thienyl)-L-alanine or L-norleucine: substrate specificity and molecular motions related to substrate binding. (2003) (88)
- Generation of Reactive Oxygen Species by Tyrosine Hydroxylase: A Possible Contribution to the Degeneration of Dopaminergic Neurons? (1997) (86)
- On the heterogeneity of beef heart cytochrome c. 3. A kinetic study of the non-enzymic deamidation of the main subfractions (Cy I-Cy 3). (1966) (84)
- On the mechanism of induction of the enzyme systems for peroxisomal beta-oxidation of fatty acids in rat liver by diets rich in partially hydrogenated fish oil. (1988) (79)
- Regulation of recombinant human tyrosine hydroxylase isozymes by catecholamine binding and phosphorylation. Structure/activity studies and mechanistic implications. (1992) (78)
- Electron carriers of the bovine adrenal chromaffin granules. (1971) (78)
- Diabetes and Pancreatic Exocrine Dysfunction Due to Mutations in the Carboxyl Ester Lipase Gene-Maturity Onset Diabetes of the Young (CEL-MODY) (2011) (75)
- Energy-dependent accumulation of iron by isolated rat liver mitochondria. I. General features. (1973) (73)
- On the heterogeneity of beef heart cytochrome c. IV. Isoelectric fractionation by electrolysis in a natural pH-gradient. (1966) (72)
- Cytochrome b 561 of the bovine adrenal chromaffin granules. A high potential b-type cytochrome. (1971) (71)
- Polydispersity of rat liver peroxisomes induced by the hypolipidemic and carcinogenic agent clofibrate. (1981) (70)
- Partial characterization and three-dimensional-structural localization of eight mutations in exon 7 of the human phenylalanine hydroxylase gene associated with phenylketonuria. (1998) (68)
- Time course of changes in nociception after 5,6-dihydroxytryptamine lesions of descending 5-HT pathways (1983) (66)
- Sedimentation coefficient and buoyant density of brown adipose tissue mitochondria from guinea pigs. (1975) (64)
- Soluble tyrosine hydroxylase (tyrosine 3-monooxygenase) from bovine adrenal medulla: large-scale purification and physicochemical properties. (1988) (63)
- The effect of ligands of phenylalanine 4-monooxygenase on the cAMP-dependent phosphorylation of the enzyme. (1984) (62)
- Multiple molecular forms of bovine heart cytochrome c. V. A comparative study of their physicochemical properties and their reactions in biological systems. (1967) (60)
- Isolation and characterization of noradrenalin storage granules of bovine adrenal medulla. (1979) (59)
- Purification and characterization of the blue-green rat phaeochromocytoma (PC12) tyrosine hydroxylase with a dopamine-Fe(III) complex. Reversal of the endogenous feedback inhibition by phosphorylation of serine-40. (1992) (59)
- Acyl-CoA synthetase activity of rat liver microsomes. Substrate specificity with special reference to very-long-chain and isomeric fatty acids. (1981) (58)
- Effects of marine oil diet on peroxisomes and mitochondria of rat liver. A combined biochemical and morphometric study. (1981) (58)
- Phosphorylation of recombinant human phenylalanine hydroxylase: effect on catalytic activity, substrate activation and protection against non-specific cleavage of the fusion protein by restriction protease. (1996) (56)
- ATP‐dependent proton translocation in resealed chromaffin granule ghosts (1977) (55)
- Oxidoreductase activities of chromaffin granule ghosts isolated from the bovine adrenal medulla. (1980) (55)
- Drug-induced parkinsonism: cinnarizine and flunarizine are potent uncouplers of the vacuolar H+-ATPase in catecholamine storage vesicles (1999) (54)
- Long-chain acyl-CoA esters and acyl-CoA binding protein are present in the nucleus of rat liver cells. (2000) (53)
- Ascorbate as a natural constituent of chromaffin granules from the bovine adrenal medulla (1975) (53)
- PKU mutation (D143G) associated with an apparent high residual enzyme activity: Expression of a kinetic variant form of phenylalanine hydroxylase in three different systems (1996) (52)
- Ubiquitination of soluble and membrane-bound tyrosine hydroxylase and degradation of the soluble form. (2002) (52)
- PKU mutation G46S is associated with increased aggregation and degradation of the phenylalanine hydroxylase enzyme (1996) (51)
- Crystallographic analysis of the human phenylalanine hydroxylase catalytic domain with bound catechol inhibitors at 2.0 A resolution. (1998) (50)
- Acyl-CoA Esters Antagonize the Effects of Ligands on Peroxisome Proliferator-activated Receptor α Conformation, DNA Binding, and Interaction with Co-factors* (2001) (50)
- Energy-dependent accumulation of iron by isolated rat liver mitochondria. II. Relationship to the active transport of Ca2+. (1973) (50)
- Microheterogeneity of recombinant human phenylalanine hydroxylase as a result of nonenzymatic deamidations of labile amide containing amino acids. Effects on catalytic and stability properties. (2000) (50)
- Subcellular distribution of ascorbate in bovine adrenal medulla. Evidence for accumulation in chromaffin granules against a concentration gradient. (1980) (48)
- Dopamine oxidation generates an oxidative stress mediated by dopamine semiquinone and unrelated to reactive oxygen species. (1997) (46)
- Phosphorylation and mutations of Ser(16) in human phenylalanine hydroxylase. Kinetic and structural effects. (2002) (46)
- Annexin A2 recognises a specific region in the 3'-UTR of its cognate messenger RNA. (2006) (45)
- Purification of cytochrome b-561. An integral heme protein of the adrenal chromaffin granule membrane. (1974) (45)
- An improved method for the large-scale isolation of chromaffin granules from bovine adrenal medulla. (1971) (44)
- Effect of a high-fat diet with partially hydrogenated fish oil on long-chain fatty acid metabolizing enzymes in subcellular fractions of rat liver. (1987) (43)
- On the heterogeneity of beef heart cytochrome c. II. Some physico-chemical properties of the main subfractions (Cy I-Cy 3). (1966) (41)
- On the Heterogeneity of Beef Heart Cytochrome c. I. Separation and Isolation of Subfractions by Disc Electrophoresis and Column Chromatography. (1964) (41)
- Use of surface plasmon resonance for real-time measurements of the global conformational transition in human phenylalanine hydroxylase in response to substrate binding and catalytic activation. (2001) (40)
- Determination of sedimentation coefficients of subcellular particles of rat liver homogenates. A theoretical and experimental approach. (1973) (40)
- Some aspects of the phosphorylation of phenylalanine 4-monooxygenase by a calcium-dependent and calmodulin-dependent protein kinase. (1984) (38)
- Tyrosine hydroxylase binds tetrahydrobiopterin cofactor with negative cooperativity, as shown by kinetic analyses and surface plasmon resonance detection. (1999) (38)
- Dophamine β‐Hhydroxylase: Evidence against a ping‐pong mechanism (1974) (38)
- Lactoperoxidase from human colostrum. (1989) (37)
- One-electron oxidation of catecholamines generates free radicals with an in vitro toxicity correlating with their lifetime. (2006) (36)
- Catalytic activation of human glucokinase by substrate binding – residue contacts involved in the binding of D‐glucose to the super‐open form and conformational transitions (2008) (36)
- Isolation and characterization of tetrahydropterin oxidation products generated in the tyrosine 3-monooxygenase (tyrosine hydroxylase) reaction. (1987) (36)
- Recombinant human phenylalanine hydroxylase is a substrate for the ubiquitin-conjugating enzyme system. (1996) (36)
- Effect of the hydrophile-lipophile balance of non-ionic detergents (Triton X-series) on the solubilization of biological membranes and their integral b-type cytochromes. (1976) (36)
- Rapid and sensitive assay of tyrosine 3-monooxygenase activity by high-performance liquid chromatography using the native fluorescence of DOPA. (1980) (35)
- Determination of CoASH by high-performance liquid chromatography and its application in the assay of long-chain acyl-CoA derivatives. (1979) (35)
- The incorporation of divalent metal ions into recombinant human tyrosine hydroxylase apoenzymes studied by intrinsic fluorescence and 1H-NMR spectroscopy. (1992) (35)
- Active and passive transport of dopamine in chromaffin granule ghosts isolated from bovine adrenal medulla. (1979) (35)
- Allosteric Activation of Human Glucokinase by Free Polyubiquitin Chains and Its Ubiquitin-dependent Cotranslational Proteasomal Degradation* (2007) (33)
- SUMOylation of Pancreatic Glucokinase Regulates Its Cellular Stability and Activity* (2013) (32)
- The mRNA-binding site of annexin A2 resides in helices C-D of its domain IV. (2007) (32)
- The p58-positive pre-golgi intermediates consist of distinct subpopulations of particles that show differential binding of COPI and COPII coats and contain vacuolar H(+)-ATPase. (2000) (32)
- Phosphatidylinositol kinase of bovine adrenal chromaffin granules: kinetic properties and inhibition by low concentrations of Ca2+. (1988) (31)
- Heterotetrameric forms of human phenylalanine hydroxylase: co-expression of wild-type and mutant forms in a bicistronic system. (2011) (31)
- Electron Paramagnetic Resonance of the Copper in Dopamine β‐Monooxygenase (1980) (31)
- Electron carriers of the noradrenaline storage vesicles from bovine splenic nerves. (1971) (31)
- EPR and 1H-NMR spectroscopic studies on the paramagnetic iron at the active site of phenylalanine hydroxylase and its interaction with substrates and inhibitors. (1991) (31)
- Phenylketonuria as a protein misfolding disease: The mutation pG46S in phenylalanine hydroxylase promotes self-association and fibril formation. (2011) (31)
- Dopamine β‐monooxygenase: electron paramagnetic resonance and oxidation‐reduction properties of the enzyme‐bound copper (1978) (30)
- Studies on the energy state of isolated brown adipose tissue mitochondria. The cytochrome b complex as a probe of the energy state of the mitochondrial inner membrane. (1972) (30)
- A comparison of kinetic and regulatory properties of the tetrameric and dimeric forms of wild-type and Thr427-->Pro mutant human phenylalanine hydroxylase: contribution of the flexible hinge region Asp425-Gln429 to the tetramerization and cooperative substrate binding. (2001) (30)
- Fluorometric detection of tryptophan, 5-hydroxytryptophan, and 5-hydroxytryptamine (serotonin) in high-performance liquid chromatography. (1980) (30)
- Stereoselective effects in the interactions of pterin cofactors with rat-liver phenylalanine 4-monooxygenase. (1986) (30)
- Studies on the regulatory properties of the pterin cofactor and dopamine bound at the active site of human phenylalanine hydroxylase. (2003) (29)
- Cooperative homotropic interaction of L-noradrenaline with the catalytic site of phenylalanine 4-monooxygenase. (1990) (29)
- Probing the Role of Crystallographically Defined/Predicted Hinge-bending Regions in the Substrate-induced Global Conformational Transition and Catalytic Activation of Human Phenylalanine Hydroxylase by Single-site Mutagenesis* (2004) (28)
- Inhibition by N‐ethylmaleimide of the MgATP‐driven proton pump of the chromaffin granules (1982) (28)
- Binding of the viral immunogenic octapeptide VSV8 to native glucose‐regulated protein Grp94 (gp96) and its inhibition by the physiological ligands ATP and Ca2+ (2006) (28)
- Evidence for a negative modulating effect of erucic acid on the peroxisomal beta-oxidation enzyme system and biogenesis in rat liver. (1983) (28)
- Substrate-induced conformational transition in human phenylalanine hydroxylase as studied by surface plasmon resonance analyses: the effect of terminal deletions, substrate analogues and phosphorylation. (2003) (27)
- NADH(NADPH): (acceptor) oxidoreductase activities of the bovine adrenal chromaffin granules. (1973) (27)
- The Effect of Substrate, Dihydrobiopterin, and Dopamine on the EPR Spectroscopic Properties and the Midpoint Potential of the Catalytic Iron in Recombinant Human Phenylalanine Hydroxylase* (2001) (27)
- Energy-dependent accumulation of iron by isolated rat liver mitochondria. V. Effect of factors controlling respiration and oxidative phosphorylation. (1975) (26)
- Cytochrome b-561 as the single heme protein of the bovine adrenal chromaffin granule membrane. (1974) (25)
- Ubiquitinated annexin A2 is enriched in the cytoskeleton fraction (2005) (24)
- Expression of wild type and mutant forms of human phenylalanine hydroxylase in E. coli. (1993) (24)
- Tight binding of deoxyribonucleotide triphosphates to human thymidine kinase 2 expressed in Escherichia coli. Purification and partial characterization of its dimeric and tetrameric forms. (2003) (24)
- The effect of calcium channel blockers on the H(+)-ATPase and bioenergetics of catecholamine storage vesicles. (1991) (24)
- Purification and kinetic properties of a membrane-bound phosphatidylinositol kinase of the bovine adrenal medulla. (1990) (24)
- Phenylalanine as substrate for tyrosine hydroxylase in bovine adrenal chromaffin cells. (1990) (24)
- On the amphiphilic and hydrophilic forms of dopamine β‐mono‐oxygenase in bovine adrenal medulla (1979) (23)
- The cooperative binding of phenylalanine to phenylalanine 4-monooxygenase studied by 1H-NMR paramagnetic relaxation. Changes in water accessibility to the iron at the active site upon substrate binding. (1993) (23)
- NH2-Terminal sequence of dopamine β-hydroxylase from bovine adrenal medulla (1977) (22)
- Phenylalanine positively modulates the cAMP-dependent phosphorylation and negatively modulates the vasopressin-induced and okadaic-acid-induced phosphorylation of phenylalanine 4-monooxygenase in intact rat hepatocytes. (1992) (21)
- Binding of ATP at the active site of human pancreatic glucokinase – nucleotide-induced conformational changes with possible implications for its kinetic cooperativity (2011) (21)
- Induction of megamitochondria by cuprizone(biscyclohexanone oxaldihydrazone). Evidence for an inhibition of the mitochondrial division process. (1980) (21)
- Conformation and interaction of phenylalanine with the divalent cation at the active site of human recombinant tyrosine hydroxylase as determined by proton NMR. (1993) (21)
- Acyl-CoA synthetase activity of rat heart mitochondria. Substrate specificity with special reference to very-long-chain and isomeric fatty acids. (1983) (21)
- A kinetic and conformational study on the interaction of tetrahydropteridines with tyrosine hydroxylase. (2000) (21)
- Energy-dependent accumulation of iron by isolated rat liver mitochondria. 3. Submitochondrial localization of the iron accumulated. (1974) (21)
- Deamidations in Recombinant Human Phenylalanine Hydroxylase (2003) (20)
- Comparative study of physicochemical properties of two c-type cytochromes of Rhodospirillum molischianum. (1970) (20)
- The pattern of iron—sulfur centers in brown adipose tissue mitochondria: Preponderance of ETF dehydrogenase and invariance with the thermogenic state (1976) (20)
- Modulation by pterins of the phosphorylation and phenylalanine activation of phenylalanine 4-mono-oxygenase. (1987) (20)
- Studies on the Peroxidase Effect of Cytochrome c. II. Purification of Beef Heart Cytochrome c by Gel Filtration. (1964) (20)
- Deamidation of labile asparagine residues in the autoregulatory sequence of human phenylalanine hydroxylase. (2003) (19)
- On the rate-limiting step in the transfer of long-chain acyl groups across the inner membrane of brown adipose tissue mitochondria. (1978) (19)
- Studies on catalase compartmentation in digitonin-treated rat hepatocytes. (1986) (19)
- Purification of herpes simplex virus type 1 by density gradient centrifugation and estimation of the sedimentation coefficient of the virion (1997) (18)
- A general and rational approach to the optimal recovery of mitochondria by differential centrifugation in homogenous media. (1975) (18)
- Purification and kinetic properties of a soluble phosphatidylinositol-4-phosphate kinase of the bovine adrenal medulla with emphasis on its inhibition by calcium ions. (1989) (18)
- Fluorimetric detection of octopamine in high-performance liquid chromatography and its application to the assay of dopamine beta-monooxygenase in human serum. (1978) (18)
- Colocalization of Ca2+-ATPase and GRP94 with p58 and the effects of thapsigargin on protein recycling suggest the participation of the pre-Golgi intermediate compartment in intracellular Ca2+ storage. (2002) (18)
- Kinetic analysis and ligand-induced conformational changes in dimeric and tetrameric forms of human thymidine kinase 2. (2005) (18)
- GCK-MODY diabetes as a protein misfolding disease: The mutation R275C promotes protein misfolding, self-association and cellular degradation (2014) (18)
- Catecholamine Metabolism: An Update on Key Biosynthetic Enzymes and Vesicular Monoamine Transporters (2002) (17)
- Acyl-CoA synthetase activity of brown adipose tissue mitochondria. Substrate specificity and its relation to the endogenous pool of long-chain fatty acids. (1980) (17)
- Hydrodynamic parameters and isolation of mitochondria, microperoxisomes and microsomes of rat heart. (1982) (17)
- Evidence that deletion of coding sequences in the 5' end of the thymidine kinase gene of herpes simplex virus type 1 affects the stability of the gene products. (1987) (17)
- Phosphorylation and Mutations of Ser16 in Human Phenylalanine Hydroxylase (2002) (17)
- The content of long-chain free fatty acids and their effect on energy transduction in chromaffin granule ghosts. (1984) (17)
- Studies on the Peroxidase Effect of Cytochrome c. III. A Kinetic Study of the Over-all Reaction. (1964) (17)
- Cytochrome b-561 of the bovine adrenal chromaffin granules. Molecular weight and hydrodynamic properties in micellar solutions of triton X-100. (1981) (17)
- Long-chain acyl-CoA synthetase and "outer" carnitine long-chain acyltransferase activities of intact brown adipose tissue mitochondria. (1978) (16)
- The peroxisomal beta-oxidation enzyme system of rat heart. Basal level and effect of the peroxisome proliferator clofibrate. (1994) (16)
- Demonstration and partial purification of lactoperoxidase from human colostrum (1984) (16)
- Studies on the energy state of isolated brown adipose tissue mitochondria. Effect of adenine nucleotides and oligomycin on the generation and dissipation of the "energy potential". (1973) (16)
- A fluorometric assay of acyl-CoA oxidase activity by a coupled peroxidatic reaction: elimination of interfering side reactions. (1991) (16)
- Characterization of phospholipase activities in chromaffin granule ghosts isolated from the bovine adrenal medulla. (1987) (15)
- Isolation and characterization of quinonoid dihydropterins by high-performance liquid chromatography (1983) (15)
- An adenosine 3':5'-monophosphate-adenosine binding protein from mouse liver: some physicochemical properties. (1978) (15)
- Studies on Mg2+-dependent ATPase in bovine adrenal chromaffin granules. With special reference to the effect of inhibitors and energy coupling. (1987) (15)
- Reticulocyte Destruction in Paroxysmal Nocturnal Haemoglobinuria (1962) (14)
- Engineering, biophysical characterisation and binding properties of a soluble mutant form of annexin A2 domain IV that adopts a partially folded conformation. (2006) (14)
- Synergistic Antiproliferative Actions of Cyclic Adenosine 3',5'-Monophosphate, Interleukin-1β, and Activators of Ca2+/Calmodulin-Dependent Protein Kinase in Primary Hepatocytes. (1997) (14)
- GCK-MODY diabetes associated with protein misfolding, cellular self-association and degradation. (2012) (14)
- Studies on the ferrochelatase activity of isolated rat liver mitochondria with special reference to the effect of oxidizable substrates and oxygen concentration. (1976) (14)
- Relation between induction of ornithine decarboxylase and specific gene expression in rat liver in response to the tumor promoter agent clofibrate. (1986) (13)
- Phosphatidylinositol kinase of bovine adrenal chromaffin granules. Modulation by hydrophilic and amphiphilic cations. (1988) (13)
- A low-cost integrator for preparative ultracentrifuges. (1974) (13)
- Microperoxisomes and mitochondria of brown adipose tissue. Hydrodynamic parameters, isolation and capacity of long-chain fatty acid oxidation. (1982) (13)
- Inactivation of purified phenylalanine hydroxylase by dithiothreitol. (1992) (13)
- Evidence from EPR spectroscopy that phosphorylation of Ser‐40 in bovine adrenal tyrosine hydroxylase facilitates the reduction of high‐spin Fe(III) under turnover conditions (1989) (13)
- Conjugation of phenylalanine hydroxylase with polyubiquitin chains catalysed by rat liver enzymes. (2001) (12)
- The effect of prenylamine and organic nitrates on the bioenergetics of bovine catecholamine storage vesicles. (1990) (12)
- Effects of essential fatty acid deficiency on mitochondria and peroxisomes in rat hepatocytes with special reference to a partially hydrogenated fish oil diet. (1986) (12)
- Inhibition of the H+‐ATPase in bovine adrenal chromaffin granule ghosts by diethylstilbestrol Evidence for a tight coupling between ATP hydrolysis and proton translocation (1988) (12)
- Energy-dependent redox reactions of two b-type cytochromes in brown adipose tissue mitochondria. (1973) (12)
- Studies on the chelate structure of the high-potential iron protein of Chromatium. (1969) (11)
- Comparison of the ultrastructure of adrenaline and noradrenaline storage granules of bovine adrenal medulla. (1979) (11)
- On the polydispersity of bovine adrenal chromaffin granules Analytical differential centrifugation in isotonic homogeneous medium (1978) (11)
- The myoglobin content in red, intermediate and white fibres of the swimming muscle sin three species of shark–a comparative study using high‐performance liquid chromatography (1981) (11)
- The assignment of the Ca2+‐ATPase activity of chromaffin granules to the proton translocating ATPase (1985) (11)
- Phenylalanine 4-monooxygenase from bovine and rat liver: Some physical and chemical properties (1982) (10)
- Inhibition of aromatic l‐amino acid decarboxylase activity by human autoantibodies (2000) (10)
- Interaction of substrate and pterin cofactor with the metal of human tyrosine hydroxylase as determined by 1H-NMR. (1993) (10)
- On the mechanism of stimulation of peroxisomal beta-oxidation in rat heart by partially hydrogenated fish oil. (1995) (10)
- The G46S-hPAH mutant protein: a model to study the rescue of aggregation-prone PKU mutations by chaperones. (2011) (9)
- Spectrophotometric Titration of Tyrosine Residues of Beef Heart Cytochrome c. (1964) (9)
- Increase in mitochondrial content of long-chain acyl-CoA in brown adipose tissue during cold-acclimation. (1984) (9)
- Autoreduction of horse heart ferricytochrome c. Kinetic and equilibrium studies of the over-all reaction. (1971) (8)
- Studies on the hemolytic mechanism in March hemoglobinuria. (2009) (8)
- Isolation and chemical properties of two c-type cytochromes of Rhodospirillum molischianum. (1970) (8)
- Dopamine beta-monooxygenase: reduced enzyme needs additional reductant for completion of the catalytic cycle. (1978) (8)
- Rapid and sensitive assay of ornithine decarboxylase activity by high-performance liquid chromatography of the o-phthalaldehyde derivative of putrescine. (1987) (8)
- Isolation from the microsomal fraction of rat liver of a subfraction highly enriched in uncoated endocytic vesicles with high H+‐ATPase activity and a 50 kDa phosphoprotein (1985) (7)
- Freeze-fracture study of rat liver peroxisomes: evidence for an induction of intramembrane particles by agents stimulating peroxisomal proliferation. (1990) (7)
- Transient Up‐Regulation of Liver Mitochondrial Thymidine Kinase Activity in Proliferating Mitochondria (2001) (7)
- Studies on the Peroxidase Effect of Cytochrome c. I. Peroxidase Activity in Subcellular Fractions from the Rat Kidney, and the Assay of Soluble Cytochrome c by Paper Electrophoresis. (1964) (7)
- Spectral properties of the oestrogen-induced rat uterus peroxidase II and some of its derivatives. (1982) (7)
- The effect of phosphorylation at Ser-40 on the structure and thermal stability of tyrosine hydroxylase. (1998) (7)
- Studies on the peroxidase effect of cytochrome c. V. Spectrophotometric titration of a reversible conformational change of ferricytochrome c in acid aqueous solution. (1966) (7)
- On the polydispersity of mitochondria in tissue homogenates and the determination of the average sedimentation coefficients of mixed populations of mitochondria. (1978) (6)
- Pancytopenia and bone marrow hypoplasia in a case of paroxysmal nocturnal hemoglobinuria. (2009) (6)
- Inhibition of dopamine β‐mono‐oxygenase by non‐ionic detergents of the triton X‐series (1977) (6)
- Proton NMR Studies on the Conformation of the Pterin Cofactor Bound at the Active Site of Recombinant Human Tyrosine Hydroxylase (1998) (6)
- The PKU mutation S349P causes complete loss of catalytic activity in the recombinant phenylalanine hydroxylase enzyme (1995) (6)
- Characterization of a novel pterin intermediate formed in the catalytic cycle of tyrosine hydroxylase. (1996) (6)
- In vitro binding of protoheme IX and protoporphyrin IX to components in the matrix of rat liver mitochondria. (1979) (5)
- Nuclear import of glucokinase in pancreatic beta-cells is mediated by a nuclear localization signal and modulated by SUMOylation (2017) (5)
- Phenylalanine 4-monooxygenase from bovine liver. (1987) (5)
- Native and Phosphorylated Bovine Adrenal Tyrosine 3-Monooxygenase. Interactions with Tetrahydropterins and Substrate and Stability of the Formed 4a-Hydroxy-Tetrahydrobiopterin (1989) (5)
- 3-(2-Thienyl)-L-Alanine as a Competitive Substrate Analogue and Activator of Human Phenylalanine Hydroxylase (2002) (4)
- Iron Transporting System of Mitochondria (1977) (4)
- Artifactual subcellular distribution of dopamine beta-hydroxylase. Effects of dilution and non-specific protein on the dopamine beta-hydroxylase activity of membranes of adrenomedullary and sympathetic nerve vesicles. (1973) (4)
- PKU mutation p.G46S prevents the stereospecific binding of l‐phenylalanine to the dimer of human phenylalanine hydroxylase regulatory domain (2017) (4)
- The p 58-positive pre-Golgi intermediates consist of distinct subpopulations of particles that show differential binding of COPI and COPII coats and contain vacuolar H +-ATPase (4)
- Demonstration of Peroxidase Activity in the Rat Kidney and Liver: Peroxidase Effect of Cytochrome c (1962) (4)
- POLYDISPERSITY AND BIOCHEMICAL HETEROGENEITY OF RAT LIVER PEROXISOMES INDUCED BY CLOFIBRATE: A MODEL FOR STUDYING PEROXISOMAL BIOGENESIS * (1982) (4)
- Anion- and pH-dependent activation of the soluble form of dopamine beta-hydroxylase. (2003) (4)
- Possible Contributions of Labile Asparagine Residues to Differences in Regulatory Properties of Human and Rat Phenylalanine Hydroxylase (2002) (3)
- Anion-and pH-dependent activation of the soluble form of dopamine β-hydroxylase (3)
- Catalytic Domain of Human Phenylalanine Hydroxylase Fe(II) in Complex with Tetrahydrobiopterin (2002) (3)
- Spectroscopic characterization of iron containing blue-green tyrosine hydroxylase from rat pheochromocytoma (PC-12) tumours and bovine adrenal medulla (1989) (3)
- The copper-enzyme dopamine beta-monooxygenase: studies on the ability of several metals to inhibit the enzyme activity and to replace the copper. (1984) (3)
- The choice of resuspension medium for isolated rat liver nuclei: Effects on nuclear morphology andin vitro transcription (1994) (3)
- Substituting Tyr138 in the active site loop of human phenylalanine hydroxylase affects catalysis and substrate activation (2017) (3)
- Studies on the Peroxidase Effect of Cytochrome c. IV. The Influence of pH and Certain Anions on the Over-all Reaction. (1965) (3)
- Electron paramagnetic resonance of the copper in dopamine beta-monooxygenase. Rapid reduction by ascorbate, the steady-state redox level, chelation with EDTA, and reactivation of the apoenzyme by added copper. (1980) (2)
- Analytical differential centrifugation of cell organelles. (1988) (2)
- The Condensed Matrix of Mature Chromaffin Granules (2002) (2)
- Synergistic antiproliferative actions of cyclic adenosine 3',5'-monophosphate, interleukin-1beta, and activators of Ca2+/calmodulin-dependent protein kinase in primary hepatocytes. (1997) (2)
- Catecholamine releasing effect of calcium channel blockers: Inhibition of the bioenergetics of catecholamine storage vesicles (1990) (2)
- Inhibition of mitochondrial protein synthesis and energy coupling by fragment A of diphtheria toxin. (1982) (2)
- Energy-dependent accumulation of calcium antagonists in catecholamine storage vesicles. (2000) (2)
- The Release of Iron from a Subfraction of Rat Liver Highly Enriched in Endosomal Organelles Requires Both a Functional H+-ATPase and NADH (1988) (2)
- High-molecular-mass complexes of the regulatory subunits of cyclic AMP-dependent protein kinase. (1991) (2)
- Regulatory properties of tetrahydrobiopterin cofactor bound at the active site of phenylalanine hydroxylase (2000) (2)
- Characterization of the iron environment in recombinant human tyrosine hydroxylase, using Mössbauer and EPR-spectroscopy. (1993) (2)
- Catalytic Domain of Human Phenylalanine Hydroxylase Fe(II) (2002) (2)
- Bovine dihydropteridine reductase: purification by affinity chromatography and comparison of enzymes from liver and adrenal medulla. (1979) (2)
- Dopamine beta-monooxygenase. Binding to apoenzyme and rapid exchange in holoenzyme of 64Cu studied with high-performance size-exclusion gel chromatography. (1983) (2)
- NH2-terminal sequence of dopamine beta-hydroxylase from bovine adrenal medulla. (1977) (2)
- Pteridines CVII* Synthesis of 6-Azidomethyl-5,6,7,8-tetrahydropterin. Photo degradation Products and Cofactor Properties on Aromatic Amino Acid Monooxygenases (1995) (1)
- Metabolic effects of 3-thia fatty acid in cancer cells. (1999) (1)
- L-Dopa Responsive Dystonia/Infantile Parkinsonism Associated with Mutations at the Human Tyrosine Hydroxylase Locus (2002) (1)
- The condensed matrix of mature chromaffin granules. The soluble form of dopamine beta-hydroxylase is catalytically inactive. (2000) (1)
- KINETIC AND EQUILIBRIUM STUDIES ON THE AUTOREDUCTION OF HORSE-HEART FERRICYTOCHROME c (1972) (1)
- Biogenesis of neuroendocrine secretory vesicles (1993) (1)
- Modulation by ligands of the phosphorylation state of phenylalanine 4-monooxygenase in intact hepatocytes (1990) (1)
- Regulatory Properties of the Tetrahydropterin Cofactor in the Reaction Catalysed by Human Tyrosine Hydroxylase Isoforms 1–4 (2002) (0)
- A HISTOCHEMICAL TECHNIC FOR THE DEMONSTRATION OF CYTOCHROME C. (1963) (0)
- [Trichinosis in present day Norway; observations on a diagnosed case]. (1958) (0)
- [Wegener's syndrome (Wegener's syndrome (Wegener's granulomatosis)]. (1961) (0)
- Structural similarities of c type cytochromes of rhodospirillum molischianum abstract (1969) (0)
- The Position of Trichinosis in Norway Today. (1958) (0)
- Development of a bicistronic expression system for co-expression of different mutant alleles of phenylalanine hydroxylase (2006) (0)
- The copper of dopamine β-Monooxygenase: High accessibility and rapid exchange (1983) (0)
- Spectroscopic Studies on Tyrosine 3-Monooxygenase from Bovine Adrenal Medulla: A Blue Iron Protein (1986) (0)
- Bovine dihydropteridine reductase (1979) (0)
- Dopamine beta-hydroxylase: evidence against a ping-pong mechanism. (1974) (0)
- Structural Insight into the Aromatic Amino Acid Hydroxylases and Their Disease‐Related Mutant Forms (1999) (0)
- Pseudomonas aeruginosa phenylalanine hydroxylase at 1.6 Å resolution : structural and biochemical characterization (2003) (0)
- Catalytic Domain of Human Phenylalanine Hydroxylase (Fe(II)) in Complex with Tetrahydrobiopterin and Thienylalanine (2003) (0)
- GCK-MODY diabetes as a protein misfolding disease : The mutation R 275 C promotes protein misfolding (2013) (0)
- Interallelic complementation and phenylketonuria (2008) (0)
- [Clinical trial of a new oral mercurial diuretic (3-hydroxymercuri-2-methoxy-1-succinimido-propan-theophyllinewater) in chronic congestive heart failure]. (1958) (0)
- CRYSTAL STRUCTURE OF DOUBLE TRUNCATED HUMAN PHENYLALANINE HYDROXYLASE WITH BOUND 7,8-DIHYDRO-L-BIOPTERIN (2000) (0)
- [Intravenous glucagon tolerance test in diagnosis of chronic hypoglycemia]. (1959) (0)
- Crystal structure of ternary complex of the catalytic domain of human phenylalanine hydroxylase ((FeII)) complexed with tetrahydrobiopterin and thienylalanine (2003) (0)
- Purification and characterization of dopamine beta-hydroxylase from bovine adrenal medulla. (1976) (0)
- Effect of diphtheria toxin fragment A on energy coupling in mitochondria. Studies on mouse liver mitoplasts (1983) (0)
- THE DOPAMINE HYDROXYLATING SYSTEM OF BOVINE ADRENAL CHROMAFFIN GRANULES (1982) (0)
- EFFECTS OF MARINE OIL DIET ON PEROXISOMES AND MITOCHONDRIA IN RAT LIVER. A MANIFESTATION OF ESSENTIAL FATTY ACID DEFICIENCY (1981) (0)
- Effect of oxidative stress on catecholamine storage vesicles (1992) (0)
- HUMAN PHENYLALANINE HYDROXYLASE CATALYTIC DOMAIN DIMER WITH BOUND NOR-ADRENALINE INHIBITOR (1999) (0)
- HUMAN PHENYLALANINE HYDROXYLASE CATALYTIC DOMAIN DIMER WITH BOUND L-DOPA (3,4-DIHYDROXYPHENYLALANINE) INHIBITOR (1999) (0)
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