Torgeir Flatmark

Torgeir Flatmark's AcademicInfluence.com Rankings

Torgeir Flatmark

Biology

#10919

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#14283

Historical Rank

Cell Biology

#534

World Rank

#546

Historical Rank

Biochemistry

#1770

World Rank

#1906

Historical Rank

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Biology

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Torgeir Flatmark's Published Works

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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Characterization of the immature secretory granule, an intermediate in granule biogenesis (1991) (231)
Recessively inherited L-DOPA-responsive dystonia caused by a point mutation (Q381K) in the tyrosine hydroxylase gene. (1995) (199)
Recessively inherited L-DOPA-responsive parkinsonism in infancy caused by a point mutation (L205P) in the tyrosine hydroxylase gene. (1996) (181)
Brown adipose tissue mitochondria. (1975) (180)
Expression of recombinant human phenylalanine hydroxylase as fusion protein in Escherichia coli circumvents proteolytic degradation by host cell proteases. Isolation and characterization of the wild-type enzyme. (1995) (170)
Crystal structure of the catalytic domain of human phenylalanine hydroxylase reveals the structural basis for phenylketonuria (1997) (165)
Structural Insight into the Aromatic Amino Acid Hydroxylases and Their Disease-Related Mutant Forms. (1999) (150)
The progenitor cell marker NG2/MPG promotes chemoresistance by activation of integrin-dependent PI3K/Akt signaling (2008) (148)
Catecholamine biosynthesis and physiological regulation in neuroendocrine cells. (2000) (134)
Selective storage of acetylcholine, but not catecholamines, in neuroendocrine synaptic-like microvesicles of early endosomal origin (1993) (131)
Enhancement of long-chain acyl-CoA hydrolase activity in peroxisomes and mitochondria of rat liver by peroxisomal proliferators. (1984) (124)
Crystal structure of the ternary complex of the catalytic domain of human phenylalanine hydroxylase with tetrahydrobiopterin and 3-(2-thienyl)-L-alanine, and its implications for the mechanism of catalysis and substrate activation. (2002) (103)
Mitochondrial iron not bound in heme and iron-sulfur centers. Estimation, compartmentation and redox state. (1980) (99)
Energy-dependent accumulation of iron by isolated rat liver mitochondria. Requirement of reducing equivalents and evidence for a unidirectional flux of Fe(II) across the inner membrane. (1975) (99)
Multiple forms of cytochrome c in the rat. Precursor-product relationship between the main component Cy I and the minor components Cy II and Cy 3 in vivo. (1968) (96)
Recombinant human tyrosine hydroxylase isozymes. Reconstitution with iron and inhibitory effect of other metal ions. (1991) (95)
Resonance Raman studies on the blue-green-colored bovine adrenal tyrosine 3-monooxygenase (tyrosine hydroxylase). Evidence that the feedback inhibitors adrenaline and noradrenaline are coordinated to iron. (1988) (94)
Crystal structure and site-specific mutagenesis of pterin-bound human phenylalanine hydroxylase. (2000) (94)
High resolution crystal structures of the catalytic domain of human phenylalanine hydroxylase in its catalytically active Fe(II) form and binary complex with tetrahydrobiopterin. (2001) (90)
Purification and Characterization of Dopamine β ‐Hydroxylase from Bovine Adrenal Medulla (1976) (89)
Structure/function relationships in human phenylalanine hydroxylase. Effect of terminal deletions on the oligomerization, activation and cooperativity of substrate binding to the enzyme. (1996) (88)
2.0A resolution crystal structures of the ternary complexes of human phenylalanine hydroxylase catalytic domain with tetrahydrobiopterin and 3-(2-thienyl)-L-alanine or L-norleucine: substrate specificity and molecular motions related to substrate binding. (2003) (88)
Generation of Reactive Oxygen Species by Tyrosine Hydroxylase: A Possible Contribution to the Degeneration of Dopaminergic Neurons? (1997) (86)
On the heterogeneity of beef heart cytochrome c. 3. A kinetic study of the non-enzymic deamidation of the main subfractions (Cy I-Cy 3). (1966) (84)
On the mechanism of induction of the enzyme systems for peroxisomal beta-oxidation of fatty acids in rat liver by diets rich in partially hydrogenated fish oil. (1988) (79)
Regulation of recombinant human tyrosine hydroxylase isozymes by catecholamine binding and phosphorylation. Structure/activity studies and mechanistic implications. (1992) (78)
Electron carriers of the bovine adrenal chromaffin granules. (1971) (78)
Diabetes and Pancreatic Exocrine Dysfunction Due to Mutations in the Carboxyl Ester Lipase Gene-Maturity Onset Diabetes of the Young (CEL-MODY) (2011) (75)
Energy-dependent accumulation of iron by isolated rat liver mitochondria. I. General features. (1973) (73)
On the heterogeneity of beef heart cytochrome c. IV. Isoelectric fractionation by electrolysis in a natural pH-gradient. (1966) (72)
Cytochrome b 561 of the bovine adrenal chromaffin granules. A high potential b-type cytochrome. (1971) (71)
Polydispersity of rat liver peroxisomes induced by the hypolipidemic and carcinogenic agent clofibrate. (1981) (70)
Partial characterization and three-dimensional-structural localization of eight mutations in exon 7 of the human phenylalanine hydroxylase gene associated with phenylketonuria. (1998) (68)
Time course of changes in nociception after 5,6-dihydroxytryptamine lesions of descending 5-HT pathways (1983) (66)
Sedimentation coefficient and buoyant density of brown adipose tissue mitochondria from guinea pigs. (1975) (64)
Soluble tyrosine hydroxylase (tyrosine 3-monooxygenase) from bovine adrenal medulla: large-scale purification and physicochemical properties. (1988) (63)
The effect of ligands of phenylalanine 4-monooxygenase on the cAMP-dependent phosphorylation of the enzyme. (1984) (62)
Multiple molecular forms of bovine heart cytochrome c. V. A comparative study of their physicochemical properties and their reactions in biological systems. (1967) (60)
Isolation and characterization of noradrenalin storage granules of bovine adrenal medulla. (1979) (59)
Purification and characterization of the blue-green rat phaeochromocytoma (PC12) tyrosine hydroxylase with a dopamine-Fe(III) complex. Reversal of the endogenous feedback inhibition by phosphorylation of serine-40. (1992) (59)
Acyl-CoA synthetase activity of rat liver microsomes. Substrate specificity with special reference to very-long-chain and isomeric fatty acids. (1981) (58)
Effects of marine oil diet on peroxisomes and mitochondria of rat liver. A combined biochemical and morphometric study. (1981) (58)
Phosphorylation of recombinant human phenylalanine hydroxylase: effect on catalytic activity, substrate activation and protection against non-specific cleavage of the fusion protein by restriction protease. (1996) (56)
ATP‐dependent proton translocation in resealed chromaffin granule ghosts (1977) (55)
Oxidoreductase activities of chromaffin granule ghosts isolated from the bovine adrenal medulla. (1980) (55)
Drug-induced parkinsonism: cinnarizine and flunarizine are potent uncouplers of the vacuolar H+-ATPase in catecholamine storage vesicles (1999) (54)
Long-chain acyl-CoA esters and acyl-CoA binding protein are present in the nucleus of rat liver cells. (2000) (53)
Ascorbate as a natural constituent of chromaffin granules from the bovine adrenal medulla (1975) (53)
PKU mutation (D143G) associated with an apparent high residual enzyme activity: Expression of a kinetic variant form of phenylalanine hydroxylase in three different systems (1996) (52)
Ubiquitination of soluble and membrane-bound tyrosine hydroxylase and degradation of the soluble form. (2002) (52)
PKU mutation G46S is associated with increased aggregation and degradation of the phenylalanine hydroxylase enzyme (1996) (51)
Crystallographic analysis of the human phenylalanine hydroxylase catalytic domain with bound catechol inhibitors at 2.0 A resolution. (1998) (50)
Acyl-CoA Esters Antagonize the Effects of Ligands on Peroxisome Proliferator-activated Receptor α Conformation, DNA Binding, and Interaction with Co-factors* (2001) (50)
Energy-dependent accumulation of iron by isolated rat liver mitochondria. II. Relationship to the active transport of Ca2+. (1973) (50)
Microheterogeneity of recombinant human phenylalanine hydroxylase as a result of nonenzymatic deamidations of labile amide containing amino acids. Effects on catalytic and stability properties. (2000) (50)
Subcellular distribution of ascorbate in bovine adrenal medulla. Evidence for accumulation in chromaffin granules against a concentration gradient. (1980) (48)
Dopamine oxidation generates an oxidative stress mediated by dopamine semiquinone and unrelated to reactive oxygen species. (1997) (46)
Phosphorylation and mutations of Ser(16) in human phenylalanine hydroxylase. Kinetic and structural effects. (2002) (46)
Annexin A2 recognises a specific region in the 3'-UTR of its cognate messenger RNA. (2006) (45)
Purification of cytochrome b-561. An integral heme protein of the adrenal chromaffin granule membrane. (1974) (45)
An improved method for the large-scale isolation of chromaffin granules from bovine adrenal medulla. (1971) (44)
Effect of a high-fat diet with partially hydrogenated fish oil on long-chain fatty acid metabolizing enzymes in subcellular fractions of rat liver. (1987) (43)
On the heterogeneity of beef heart cytochrome c. II. Some physico-chemical properties of the main subfractions (Cy I-Cy 3). (1966) (41)
On the Heterogeneity of Beef Heart Cytochrome c. I. Separation and Isolation of Subfractions by Disc Electrophoresis and Column Chromatography. (1964) (41)
Use of surface plasmon resonance for real-time measurements of the global conformational transition in human phenylalanine hydroxylase in response to substrate binding and catalytic activation. (2001) (40)
Determination of sedimentation coefficients of subcellular particles of rat liver homogenates. A theoretical and experimental approach. (1973) (40)
Some aspects of the phosphorylation of phenylalanine 4-monooxygenase by a calcium-dependent and calmodulin-dependent protein kinase. (1984) (38)
Tyrosine hydroxylase binds tetrahydrobiopterin cofactor with negative cooperativity, as shown by kinetic analyses and surface plasmon resonance detection. (1999) (38)
Dophamine β‐Hhydroxylase: Evidence against a ping‐pong mechanism (1974) (38)
Lactoperoxidase from human colostrum. (1989) (37)
One-electron oxidation of catecholamines generates free radicals with an in vitro toxicity correlating with their lifetime. (2006) (36)
Catalytic activation of human glucokinase by substrate binding – residue contacts involved in the binding of D‐glucose to the super‐open form and conformational transitions (2008) (36)
Isolation and characterization of tetrahydropterin oxidation products generated in the tyrosine 3-monooxygenase (tyrosine hydroxylase) reaction. (1987) (36)
Recombinant human phenylalanine hydroxylase is a substrate for the ubiquitin-conjugating enzyme system. (1996) (36)
Effect of the hydrophile-lipophile balance of non-ionic detergents (Triton X-series) on the solubilization of biological membranes and their integral b-type cytochromes. (1976) (36)
Rapid and sensitive assay of tyrosine 3-monooxygenase activity by high-performance liquid chromatography using the native fluorescence of DOPA. (1980) (35)
Determination of CoASH by high-performance liquid chromatography and its application in the assay of long-chain acyl-CoA derivatives. (1979) (35)
The incorporation of divalent metal ions into recombinant human tyrosine hydroxylase apoenzymes studied by intrinsic fluorescence and 1H-NMR spectroscopy. (1992) (35)
Active and passive transport of dopamine in chromaffin granule ghosts isolated from bovine adrenal medulla. (1979) (35)
Allosteric Activation of Human Glucokinase by Free Polyubiquitin Chains and Its Ubiquitin-dependent Cotranslational Proteasomal Degradation* (2007) (33)
SUMOylation of Pancreatic Glucokinase Regulates Its Cellular Stability and Activity* (2013) (32)
The mRNA-binding site of annexin A2 resides in helices C-D of its domain IV. (2007) (32)
The p58-positive pre-golgi intermediates consist of distinct subpopulations of particles that show differential binding of COPI and COPII coats and contain vacuolar H(+)-ATPase. (2000) (32)
Phosphatidylinositol kinase of bovine adrenal chromaffin granules: kinetic properties and inhibition by low concentrations of Ca2+. (1988) (31)
Heterotetrameric forms of human phenylalanine hydroxylase: co-expression of wild-type and mutant forms in a bicistronic system. (2011) (31)
Electron Paramagnetic Resonance of the Copper in Dopamine β‐Monooxygenase (1980) (31)
Electron carriers of the noradrenaline storage vesicles from bovine splenic nerves. (1971) (31)
EPR and 1H-NMR spectroscopic studies on the paramagnetic iron at the active site of phenylalanine hydroxylase and its interaction with substrates and inhibitors. (1991) (31)
Phenylketonuria as a protein misfolding disease: The mutation pG46S in phenylalanine hydroxylase promotes self-association and fibril formation. (2011) (31)
Dopamine β‐monooxygenase: electron paramagnetic resonance and oxidation‐reduction properties of the enzyme‐bound copper (1978) (30)
Studies on the energy state of isolated brown adipose tissue mitochondria. The cytochrome b complex as a probe of the energy state of the mitochondrial inner membrane. (1972) (30)
A comparison of kinetic and regulatory properties of the tetrameric and dimeric forms of wild-type and Thr427-->Pro mutant human phenylalanine hydroxylase: contribution of the flexible hinge region Asp425-Gln429 to the tetramerization and cooperative substrate binding. (2001) (30)
Fluorometric detection of tryptophan, 5-hydroxytryptophan, and 5-hydroxytryptamine (serotonin) in high-performance liquid chromatography. (1980) (30)
Stereoselective effects in the interactions of pterin cofactors with rat-liver phenylalanine 4-monooxygenase. (1986) (30)
Studies on the regulatory properties of the pterin cofactor and dopamine bound at the active site of human phenylalanine hydroxylase. (2003) (29)
Cooperative homotropic interaction of L-noradrenaline with the catalytic site of phenylalanine 4-monooxygenase. (1990) (29)
Probing the Role of Crystallographically Defined/Predicted Hinge-bending Regions in the Substrate-induced Global Conformational Transition and Catalytic Activation of Human Phenylalanine Hydroxylase by Single-site Mutagenesis* (2004) (28)
Inhibition by N‐ethylmaleimide of the MgATP‐driven proton pump of the chromaffin granules (1982) (28)
Binding of the viral immunogenic octapeptide VSV8 to native glucose‐regulated protein Grp94 (gp96) and its inhibition by the physiological ligands ATP and Ca2+ (2006) (28)
Evidence for a negative modulating effect of erucic acid on the peroxisomal beta-oxidation enzyme system and biogenesis in rat liver. (1983) (28)
Substrate-induced conformational transition in human phenylalanine hydroxylase as studied by surface plasmon resonance analyses: the effect of terminal deletions, substrate analogues and phosphorylation. (2003) (27)
NADH(NADPH): (acceptor) oxidoreductase activities of the bovine adrenal chromaffin granules. (1973) (27)
The Effect of Substrate, Dihydrobiopterin, and Dopamine on the EPR Spectroscopic Properties and the Midpoint Potential of the Catalytic Iron in Recombinant Human Phenylalanine Hydroxylase* (2001) (27)
Energy-dependent accumulation of iron by isolated rat liver mitochondria. V. Effect of factors controlling respiration and oxidative phosphorylation. (1975) (26)
Cytochrome b-561 as the single heme protein of the bovine adrenal chromaffin granule membrane. (1974) (25)
Ubiquitinated annexin A2 is enriched in the cytoskeleton fraction (2005) (24)
Expression of wild type and mutant forms of human phenylalanine hydroxylase in E. coli. (1993) (24)
Tight binding of deoxyribonucleotide triphosphates to human thymidine kinase 2 expressed in Escherichia coli. Purification and partial characterization of its dimeric and tetrameric forms. (2003) (24)
The effect of calcium channel blockers on the H(+)-ATPase and bioenergetics of catecholamine storage vesicles. (1991) (24)
Purification and kinetic properties of a membrane-bound phosphatidylinositol kinase of the bovine adrenal medulla. (1990) (24)
Phenylalanine as substrate for tyrosine hydroxylase in bovine adrenal chromaffin cells. (1990) (24)
On the amphiphilic and hydrophilic forms of dopamine β‐mono‐oxygenase in bovine adrenal medulla (1979) (23)
The cooperative binding of phenylalanine to phenylalanine 4-monooxygenase studied by 1H-NMR paramagnetic relaxation. Changes in water accessibility to the iron at the active site upon substrate binding. (1993) (23)
NH2-Terminal sequence of dopamine β-hydroxylase from bovine adrenal medulla (1977) (22)
Phenylalanine positively modulates the cAMP-dependent phosphorylation and negatively modulates the vasopressin-induced and okadaic-acid-induced phosphorylation of phenylalanine 4-monooxygenase in intact rat hepatocytes. (1992) (21)
Binding of ATP at the active site of human pancreatic glucokinase – nucleotide-induced conformational changes with possible implications for its kinetic cooperativity (2011) (21)
Induction of megamitochondria by cuprizone(biscyclohexanone oxaldihydrazone). Evidence for an inhibition of the mitochondrial division process. (1980) (21)
Conformation and interaction of phenylalanine with the divalent cation at the active site of human recombinant tyrosine hydroxylase as determined by proton NMR. (1993) (21)
Acyl-CoA synthetase activity of rat heart mitochondria. Substrate specificity with special reference to very-long-chain and isomeric fatty acids. (1983) (21)
A kinetic and conformational study on the interaction of tetrahydropteridines with tyrosine hydroxylase. (2000) (21)
Energy-dependent accumulation of iron by isolated rat liver mitochondria. 3. Submitochondrial localization of the iron accumulated. (1974) (21)
Deamidations in Recombinant Human Phenylalanine Hydroxylase (2003) (20)
Comparative study of physicochemical properties of two c-type cytochromes of Rhodospirillum molischianum. (1970) (20)
The pattern of iron—sulfur centers in brown adipose tissue mitochondria: Preponderance of ETF dehydrogenase and invariance with the thermogenic state (1976) (20)
Modulation by pterins of the phosphorylation and phenylalanine activation of phenylalanine 4-mono-oxygenase. (1987) (20)
Studies on the Peroxidase Effect of Cytochrome c. II. Purification of Beef Heart Cytochrome c by Gel Filtration. (1964) (20)
Deamidation of labile asparagine residues in the autoregulatory sequence of human phenylalanine hydroxylase. (2003) (19)
On the rate-limiting step in the transfer of long-chain acyl groups across the inner membrane of brown adipose tissue mitochondria. (1978) (19)
Studies on catalase compartmentation in digitonin-treated rat hepatocytes. (1986) (19)
Purification of herpes simplex virus type 1 by density gradient centrifugation and estimation of the sedimentation coefficient of the virion (1997) (18)
A general and rational approach to the optimal recovery of mitochondria by differential centrifugation in homogenous media. (1975) (18)
Purification and kinetic properties of a soluble phosphatidylinositol-4-phosphate kinase of the bovine adrenal medulla with emphasis on its inhibition by calcium ions. (1989) (18)
Fluorimetric detection of octopamine in high-performance liquid chromatography and its application to the assay of dopamine beta-monooxygenase in human serum. (1978) (18)
Colocalization of Ca2+-ATPase and GRP94 with p58 and the effects of thapsigargin on protein recycling suggest the participation of the pre-Golgi intermediate compartment in intracellular Ca2+ storage. (2002) (18)
Kinetic analysis and ligand-induced conformational changes in dimeric and tetrameric forms of human thymidine kinase 2. (2005) (18)
GCK-MODY diabetes as a protein misfolding disease: The mutation R275C promotes protein misfolding, self-association and cellular degradation (2014) (18)
Catecholamine Metabolism: An Update on Key Biosynthetic Enzymes and Vesicular Monoamine Transporters (2002) (17)
Acyl-CoA synthetase activity of brown adipose tissue mitochondria. Substrate specificity and its relation to the endogenous pool of long-chain fatty acids. (1980) (17)
Hydrodynamic parameters and isolation of mitochondria, microperoxisomes and microsomes of rat heart. (1982) (17)
Evidence that deletion of coding sequences in the 5' end of the thymidine kinase gene of herpes simplex virus type 1 affects the stability of the gene products. (1987) (17)
Phosphorylation and Mutations of Ser16 in Human Phenylalanine Hydroxylase (2002) (17)
The content of long-chain free fatty acids and their effect on energy transduction in chromaffin granule ghosts. (1984) (17)
Studies on the Peroxidase Effect of Cytochrome c. III. A Kinetic Study of the Over-all Reaction. (1964) (17)
Cytochrome b-561 of the bovine adrenal chromaffin granules. Molecular weight and hydrodynamic properties in micellar solutions of triton X-100. (1981) (17)
Long-chain acyl-CoA synthetase and "outer" carnitine long-chain acyltransferase activities of intact brown adipose tissue mitochondria. (1978) (16)
The peroxisomal beta-oxidation enzyme system of rat heart. Basal level and effect of the peroxisome proliferator clofibrate. (1994) (16)
Demonstration and partial purification of lactoperoxidase from human colostrum (1984) (16)
Studies on the energy state of isolated brown adipose tissue mitochondria. Effect of adenine nucleotides and oligomycin on the generation and dissipation of the "energy potential". (1973) (16)
A fluorometric assay of acyl-CoA oxidase activity by a coupled peroxidatic reaction: elimination of interfering side reactions. (1991) (16)
Characterization of phospholipase activities in chromaffin granule ghosts isolated from the bovine adrenal medulla. (1987) (15)
Isolation and characterization of quinonoid dihydropterins by high-performance liquid chromatography (1983) (15)
An adenosine 3':5'-monophosphate-adenosine binding protein from mouse liver: some physicochemical properties. (1978) (15)
Studies on Mg2+-dependent ATPase in bovine adrenal chromaffin granules. With special reference to the effect of inhibitors and energy coupling. (1987) (15)
Reticulocyte Destruction in Paroxysmal Nocturnal Haemoglobinuria (1962) (14)
Engineering, biophysical characterisation and binding properties of a soluble mutant form of annexin A2 domain IV that adopts a partially folded conformation. (2006) (14)
Synergistic Antiproliferative Actions of Cyclic Adenosine 3',5'-Monophosphate, Interleukin-1β, and Activators of Ca2+/Calmodulin-Dependent Protein Kinase in Primary Hepatocytes. (1997) (14)
GCK-MODY diabetes associated with protein misfolding, cellular self-association and degradation. (2012) (14)
Studies on the ferrochelatase activity of isolated rat liver mitochondria with special reference to the effect of oxidizable substrates and oxygen concentration. (1976) (14)
Relation between induction of ornithine decarboxylase and specific gene expression in rat liver in response to the tumor promoter agent clofibrate. (1986) (13)
Phosphatidylinositol kinase of bovine adrenal chromaffin granules. Modulation by hydrophilic and amphiphilic cations. (1988) (13)
A low-cost integrator for preparative ultracentrifuges. (1974) (13)
Microperoxisomes and mitochondria of brown adipose tissue. Hydrodynamic parameters, isolation and capacity of long-chain fatty acid oxidation. (1982) (13)
Inactivation of purified phenylalanine hydroxylase by dithiothreitol. (1992) (13)
Evidence from EPR spectroscopy that phosphorylation of Ser‐40 in bovine adrenal tyrosine hydroxylase facilitates the reduction of high‐spin Fe(III) under turnover conditions (1989) (13)
Conjugation of phenylalanine hydroxylase with polyubiquitin chains catalysed by rat liver enzymes. (2001) (12)
The effect of prenylamine and organic nitrates on the bioenergetics of bovine catecholamine storage vesicles. (1990) (12)
Effects of essential fatty acid deficiency on mitochondria and peroxisomes in rat hepatocytes with special reference to a partially hydrogenated fish oil diet. (1986) (12)
Inhibition of the H+‐ATPase in bovine adrenal chromaffin granule ghosts by diethylstilbestrol Evidence for a tight coupling between ATP hydrolysis and proton translocation (1988) (12)
Energy-dependent redox reactions of two b-type cytochromes in brown adipose tissue mitochondria. (1973) (12)
Studies on the chelate structure of the high-potential iron protein of Chromatium. (1969) (11)
Comparison of the ultrastructure of adrenaline and noradrenaline storage granules of bovine adrenal medulla. (1979) (11)
On the polydispersity of bovine adrenal chromaffin granules Analytical differential centrifugation in isotonic homogeneous medium (1978) (11)
The myoglobin content in red, intermediate and white fibres of the swimming muscle sin three species of shark–a comparative study using high‐performance liquid chromatography (1981) (11)
The assignment of the Ca2+‐ATPase activity of chromaffin granules to the proton translocating ATPase (1985) (11)
Phenylalanine 4-monooxygenase from bovine and rat liver: Some physical and chemical properties (1982) (10)
Inhibition of aromatic l‐amino acid decarboxylase activity by human autoantibodies (2000) (10)
Interaction of substrate and pterin cofactor with the metal of human tyrosine hydroxylase as determined by 1H-NMR. (1993) (10)
On the mechanism of stimulation of peroxisomal beta-oxidation in rat heart by partially hydrogenated fish oil. (1995) (10)
The G46S-hPAH mutant protein: a model to study the rescue of aggregation-prone PKU mutations by chaperones. (2011) (9)
Spectrophotometric Titration of Tyrosine Residues of Beef Heart Cytochrome c. (1964) (9)
Increase in mitochondrial content of long-chain acyl-CoA in brown adipose tissue during cold-acclimation. (1984) (9)
Autoreduction of horse heart ferricytochrome c. Kinetic and equilibrium studies of the over-all reaction. (1971) (8)
Studies on the hemolytic mechanism in March hemoglobinuria. (2009) (8)
Isolation and chemical properties of two c-type cytochromes of Rhodospirillum molischianum. (1970) (8)
Dopamine beta-monooxygenase: reduced enzyme needs additional reductant for completion of the catalytic cycle. (1978) (8)
Rapid and sensitive assay of ornithine decarboxylase activity by high-performance liquid chromatography of the o-phthalaldehyde derivative of putrescine. (1987) (8)
Isolation from the microsomal fraction of rat liver of a subfraction highly enriched in uncoated endocytic vesicles with high H+‐ATPase activity and a 50 kDa phosphoprotein (1985) (7)
Freeze-fracture study of rat liver peroxisomes: evidence for an induction of intramembrane particles by agents stimulating peroxisomal proliferation. (1990) (7)
Transient Up‐Regulation of Liver Mitochondrial Thymidine Kinase Activity in Proliferating Mitochondria (2001) (7)
Studies on the Peroxidase Effect of Cytochrome c. I. Peroxidase Activity in Subcellular Fractions from the Rat Kidney, and the Assay of Soluble Cytochrome c by Paper Electrophoresis. (1964) (7)
Spectral properties of the oestrogen-induced rat uterus peroxidase II and some of its derivatives. (1982) (7)
The effect of phosphorylation at Ser-40 on the structure and thermal stability of tyrosine hydroxylase. (1998) (7)
Studies on the peroxidase effect of cytochrome c. V. Spectrophotometric titration of a reversible conformational change of ferricytochrome c in acid aqueous solution. (1966) (7)
On the polydispersity of mitochondria in tissue homogenates and the determination of the average sedimentation coefficients of mixed populations of mitochondria. (1978) (6)
Pancytopenia and bone marrow hypoplasia in a case of paroxysmal nocturnal hemoglobinuria. (2009) (6)
Inhibition of dopamine β‐mono‐oxygenase by non‐ionic detergents of the triton X‐series (1977) (6)
Proton NMR Studies on the Conformation of the Pterin Cofactor Bound at the Active Site of Recombinant Human Tyrosine Hydroxylase (1998) (6)
The PKU mutation S349P causes complete loss of catalytic activity in the recombinant phenylalanine hydroxylase enzyme (1995) (6)
Characterization of a novel pterin intermediate formed in the catalytic cycle of tyrosine hydroxylase. (1996) (6)
In vitro binding of protoheme IX and protoporphyrin IX to components in the matrix of rat liver mitochondria. (1979) (5)
Nuclear import of glucokinase in pancreatic beta-cells is mediated by a nuclear localization signal and modulated by SUMOylation (2017) (5)
Phenylalanine 4-monooxygenase from bovine liver. (1987) (5)
Native and Phosphorylated Bovine Adrenal Tyrosine 3-Monooxygenase. Interactions with Tetrahydropterins and Substrate and Stability of the Formed 4a-Hydroxy-Tetrahydrobiopterin (1989) (5)
3-(2-Thienyl)-L-Alanine as a Competitive Substrate Analogue and Activator of Human Phenylalanine Hydroxylase (2002) (4)
Iron Transporting System of Mitochondria (1977) (4)
Artifactual subcellular distribution of dopamine beta-hydroxylase. Effects of dilution and non-specific protein on the dopamine beta-hydroxylase activity of membranes of adrenomedullary and sympathetic nerve vesicles. (1973) (4)
PKU mutation p.G46S prevents the stereospecific binding of l‐phenylalanine to the dimer of human phenylalanine hydroxylase regulatory domain (2017) (4)
The p 58-positive pre-Golgi intermediates consist of distinct subpopulations of particles that show differential binding of COPI and COPII coats and contain vacuolar H +-ATPase (4)
Demonstration of Peroxidase Activity in the Rat Kidney and Liver: Peroxidase Effect of Cytochrome c (1962) (4)
POLYDISPERSITY AND BIOCHEMICAL HETEROGENEITY OF RAT LIVER PEROXISOMES INDUCED BY CLOFIBRATE: A MODEL FOR STUDYING PEROXISOMAL BIOGENESIS * (1982) (4)
Anion- and pH-dependent activation of the soluble form of dopamine beta-hydroxylase. (2003) (4)
Possible Contributions of Labile Asparagine Residues to Differences in Regulatory Properties of Human and Rat Phenylalanine Hydroxylase (2002) (3)
Anion-and pH-dependent activation of the soluble form of dopamine β-hydroxylase (3)
Catalytic Domain of Human Phenylalanine Hydroxylase Fe(II) in Complex with Tetrahydrobiopterin (2002) (3)
Spectroscopic characterization of iron containing blue-green tyrosine hydroxylase from rat pheochromocytoma (PC-12) tumours and bovine adrenal medulla (1989) (3)
The copper-enzyme dopamine beta-monooxygenase: studies on the ability of several metals to inhibit the enzyme activity and to replace the copper. (1984) (3)
The choice of resuspension medium for isolated rat liver nuclei: Effects on nuclear morphology andin vitro transcription (1994) (3)
Substituting Tyr138 in the active site loop of human phenylalanine hydroxylase affects catalysis and substrate activation (2017) (3)
Studies on the Peroxidase Effect of Cytochrome c. IV. The Influence of pH and Certain Anions on the Over-all Reaction. (1965) (3)
Electron paramagnetic resonance of the copper in dopamine beta-monooxygenase. Rapid reduction by ascorbate, the steady-state redox level, chelation with EDTA, and reactivation of the apoenzyme by added copper. (1980) (2)
Analytical differential centrifugation of cell organelles. (1988) (2)
The Condensed Matrix of Mature Chromaffin Granules (2002) (2)
Synergistic antiproliferative actions of cyclic adenosine 3',5'-monophosphate, interleukin-1beta, and activators of Ca2+/calmodulin-dependent protein kinase in primary hepatocytes. (1997) (2)
Catecholamine releasing effect of calcium channel blockers: Inhibition of the bioenergetics of catecholamine storage vesicles (1990) (2)
Inhibition of mitochondrial protein synthesis and energy coupling by fragment A of diphtheria toxin. (1982) (2)
Energy-dependent accumulation of calcium antagonists in catecholamine storage vesicles. (2000) (2)
The Release of Iron from a Subfraction of Rat Liver Highly Enriched in Endosomal Organelles Requires Both a Functional H+-ATPase and NADH (1988) (2)
High-molecular-mass complexes of the regulatory subunits of cyclic AMP-dependent protein kinase. (1991) (2)
Regulatory properties of tetrahydrobiopterin cofactor bound at the active site of phenylalanine hydroxylase (2000) (2)
Characterization of the iron environment in recombinant human tyrosine hydroxylase, using Mössbauer and EPR-spectroscopy. (1993) (2)
Catalytic Domain of Human Phenylalanine Hydroxylase Fe(II) (2002) (2)
Bovine dihydropteridine reductase: purification by affinity chromatography and comparison of enzymes from liver and adrenal medulla. (1979) (2)
Dopamine beta-monooxygenase. Binding to apoenzyme and rapid exchange in holoenzyme of 64Cu studied with high-performance size-exclusion gel chromatography. (1983) (2)
NH2-terminal sequence of dopamine beta-hydroxylase from bovine adrenal medulla. (1977) (2)
Pteridines CVII* Synthesis of 6-Azidomethyl-5,6,7,8-tetrahydropterin. Photo degradation Products and Cofactor Properties on Aromatic Amino Acid Monooxygenases (1995) (1)
Metabolic effects of 3-thia fatty acid in cancer cells. (1999) (1)
L-Dopa Responsive Dystonia/Infantile Parkinsonism Associated with Mutations at the Human Tyrosine Hydroxylase Locus (2002) (1)
The condensed matrix of mature chromaffin granules. The soluble form of dopamine beta-hydroxylase is catalytically inactive. (2000) (1)
KINETIC AND EQUILIBRIUM STUDIES ON THE AUTOREDUCTION OF HORSE-HEART FERRICYTOCHROME c (1972) (1)
Biogenesis of neuroendocrine secretory vesicles (1993) (1)
Modulation by ligands of the phosphorylation state of phenylalanine 4-monooxygenase in intact hepatocytes (1990) (1)
Regulatory Properties of the Tetrahydropterin Cofactor in the Reaction Catalysed by Human Tyrosine Hydroxylase Isoforms 1–4 (2002) (0)
A HISTOCHEMICAL TECHNIC FOR THE DEMONSTRATION OF CYTOCHROME C. (1963) (0)
[Trichinosis in present day Norway; observations on a diagnosed case]. (1958) (0)
[Wegener's syndrome (Wegener's syndrome (Wegener's granulomatosis)]. (1961) (0)
Structural similarities of c type cytochromes of rhodospirillum molischianum abstract (1969) (0)
The Position of Trichinosis in Norway Today. (1958) (0)
Development of a bicistronic expression system for co-expression of different mutant alleles of phenylalanine hydroxylase (2006) (0)
The copper of dopamine β-Monooxygenase: High accessibility and rapid exchange (1983) (0)
Spectroscopic Studies on Tyrosine 3-Monooxygenase from Bovine Adrenal Medulla: A Blue Iron Protein (1986) (0)
Bovine dihydropteridine reductase (1979) (0)
Dopamine beta-hydroxylase: evidence against a ping-pong mechanism. (1974) (0)
Structural Insight into the Aromatic Amino Acid Hydroxylases and Their Disease‐Related Mutant Forms (1999) (0)
Pseudomonas aeruginosa phenylalanine hydroxylase at 1.6 Å resolution : structural and biochemical characterization (2003) (0)
Catalytic Domain of Human Phenylalanine Hydroxylase (Fe(II)) in Complex with Tetrahydrobiopterin and Thienylalanine (2003) (0)
GCK-MODY diabetes as a protein misfolding disease : The mutation R 275 C promotes protein misfolding (2013) (0)
Interallelic complementation and phenylketonuria (2008) (0)
[Clinical trial of a new oral mercurial diuretic (3-hydroxymercuri-2-methoxy-1-succinimido-propan-theophyllinewater) in chronic congestive heart failure]. (1958) (0)
CRYSTAL STRUCTURE OF DOUBLE TRUNCATED HUMAN PHENYLALANINE HYDROXYLASE WITH BOUND 7,8-DIHYDRO-L-BIOPTERIN (2000) (0)
[Intravenous glucagon tolerance test in diagnosis of chronic hypoglycemia]. (1959) (0)
Crystal structure of ternary complex of the catalytic domain of human phenylalanine hydroxylase ((FeII)) complexed with tetrahydrobiopterin and thienylalanine (2003) (0)
Purification and characterization of dopamine beta-hydroxylase from bovine adrenal medulla. (1976) (0)
Effect of diphtheria toxin fragment A on energy coupling in mitochondria. Studies on mouse liver mitoplasts (1983) (0)
THE DOPAMINE HYDROXYLATING SYSTEM OF BOVINE ADRENAL CHROMAFFIN GRANULES (1982) (0)
EFFECTS OF MARINE OIL DIET ON PEROXISOMES AND MITOCHONDRIA IN RAT LIVER. A MANIFESTATION OF ESSENTIAL FATTY ACID DEFICIENCY (1981) (0)
Effect of oxidative stress on catecholamine storage vesicles (1992) (0)
HUMAN PHENYLALANINE HYDROXYLASE CATALYTIC DOMAIN DIMER WITH BOUND NOR-ADRENALINE INHIBITOR (1999) (0)
HUMAN PHENYLALANINE HYDROXYLASE CATALYTIC DOMAIN DIMER WITH BOUND L-DOPA (3,4-DIHYDROXYPHENYLALANINE) INHIBITOR (1999) (0)

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