Toshiyuki Officer Resi Hamaoka
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Toshiyuki Officer Resi Hamaokabiology Degrees
Biology
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Immunology
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Biology
Toshiyuki Officer Resi Hamaoka's Degrees
- PhD Immunology University of Tokyo
- Doctorate Medicine University of Tokyo
Why Is Toshiyuki Officer Resi Hamaoka Influential?
(Suggest an Edit or Addition)Toshiyuki Officer Resi Hamaoka's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Identification of a T cell-derived b cell growth factor distinct from interleukin 2 (1982) (1027)
- Monoclonal antibodies to Pgp-1/CD44 block lympho-hemopoiesis in long- term bone marrow cultures (1990) (598)
- A mechanism underlying synergy between IL-12 and IFN-gamma-inducing factor in enhanced production of IFN-gamma. (1997) (355)
- CELL INTERACTIONS BETWEEN HISTOINCOMPATIBLE T AND B LYMPHOCYTES (1973) (336)
- Essential role for ERK2 mitogen‐activated protein kinase in placental development (2003) (301)
- Type II collagen-induced murine arthritis. I. Induction and perpetuation of arthritis require synergy between humoral and cell-mediated immunity. (1988) (280)
- Transforming growth factor-beta-induced inhibition of T cell function. Susceptibility difference in T cells of various phenotypes and functions and its relevance to immunosuppression in the tumor-bearing state. (1991) (273)
- Systemic administration of rIL-12 induces complete tumor regression and protective immunity: response is correlated with a striking reversal of suppressed IFN-gamma production by anti-tumor T cells. (1995) (238)
- Enhanced induction of antitumor T-cell responses by cytotoxic T lymphocyte-associated molecule-4 blockade: the effect is manifested only at the restricted tumor-bearing stages. (1997) (220)
- A Novel Function of Vα14+CD4+NKT Cells: Stimulation of IL-12 Production by Antigen-Presenting Cells in the Innate Immune System (1999) (218)
- Synergy of IL-12 and IL-18 for IFN-γ Gene Expression: IL-12-Induced STAT4 Contributes to IFN-γ Promoter Activation by Up-Regulating the Binding Activity of IL-18-Induced Activator Protein 11 (2002) (214)
- Cell interactions between histoincompatible T and B lymphocytes. The H-2 gene complex determines successful physiologic lymphocyte interactions. (1973) (213)
- CELL INTERACTIONS BETWEEN HISTOINCOMPATIBLE T AND B LYMPHOCYTES (1973) (196)
- Non-CD28 Costimulatory Molecules Present in T Cell Rafts Induce T Cell Costimulation by Enhancing the Association of TCR with Rafts1 (2000) (179)
- The role of tumor-specific Lyt-1+2- T cells in eradicating tumor cells in vivo. I. Lyt-1+2- T cells do not necessarily require recruitment of host's cytotoxic T cell precursors for implementation of in vivo immunity. (1984) (167)
- Antigen-induced T cell-replacing factor (TRF). III. Establishment of T cell hybrid clone continuously producing TRF and functional analysis of released TRF. (1980) (159)
- Administration of recombinant interleukin 12 prevents outgrowth of tumor cells metastasizing spontaneously to lung and lymph nodes. (1995) (156)
- Plasma cholecystokinin responses after ingestion of liquid meal and intraduodenal infusion of fat, amino acids, or hydrochloric acid in man: analysis with region specific radioimmunoassay. (1983) (151)
- A critical role for IL-18 in the proliferation and activation of NK1.1+ CD3- cells. (1998) (145)
- Differential capacities of CD4+, CD8+, and CD4-CD8- T cell subsets to express IL-18 receptor and produce IFN-gamma in response to IL-18. (1998) (143)
- A non‐peptide CCR5 antagonist inhibits collagen‐induced arthritis by modulating T cell migration without affecting anti‐collagen T cell responses (2002) (139)
- CELL INTERACTIONS BETWEEN HISTOINCOMPATIBLE T AND B LYMPHOCYTES (1973) (138)
- Synergy of IL-12 and IL-18 for IFN-gamma gene expression: IL-12-induced STAT4 contributes to IFN-gamma promoter activation by up-regulating the binding activity of IL-18-induced activator protein 1. (2002) (133)
- Cutting Edge: Fyn Is Essential for Tyrosine Phosphorylation of Csk-Binding Protein/Phosphoprotein Associated with Glycolipid-Enriched Microdomains in Lipid Rafts in Resting T Cells1 (2002) (130)
- Involvement of SHP-1 tyrosine phosphatase in TCR-mediated signaling pathways in lipid rafts. (2001) (124)
- Induction of the chemokine receptor CXCR3 on TCR‐stimulated T cells: dependence on the release from persistent TCR‐triggering and requirement for IFN‐γ stimulation (2002) (124)
- Production of rabbit antibody specific for amino-terminal residues of cholecystokinin octapeptide (CCK-8) by selective suppression of cross-reactive antibody response. (1982) (123)
- The unique target specificity of a nonpeptide chemokine receptor antagonist: selective blockade of two Th1 chemokine receptors CCR5 and CXCR3 (2003) (118)
- IMMUNOLOGICAL TOLERANCE IN BONE MARROW-DERIVED LYMPHOCYTES (1972) (117)
- Positively charged liposome functions as an efficient immunoadjuvant in inducing immune responses to soluble proteins. (1997) (112)
- Antigen-induced T cell-replacing factor (TRF). I. Functional characterization of a TRF-producing helper T cell subset and genetic studies on TRF production. (1980) (109)
- Identification of a Novel Transmembrane Semaphorin Expressed on Lymphocytes* (1996) (107)
- Regulation of T cell‐dependent and ‐independent IL‐12 production by the three Th2‐type cytokines IL‐10, IL‐6, and IL‐4 (1997) (103)
- HAPTEN-SPECIFIC IgE ANTIBODY RESPONSES IN MICE (1973) (103)
- A role for CD9 molecules in T cell activation (1996) (100)
- Both interleukin 2 and a second T cell-derived factor in EL-4 supernatant have activity as differentiation factors in IgM synthesis (1984) (96)
- Studies on the induction of tolerance to alloantigens. I. The abrogation of potentials for delayed-type-hypersensitivity response to alloantigens by portal venous inoculation with allogeneic cells. (1985) (91)
- Ontogeny of cholecystokinin‐8‐containing neuron system of the rat: An immunohistochemical analysis. I. Forebrain and upper brainstem (1983) (91)
- A Role of Interferon-γ (IFN-γ) in Tumor Immunity: T Cells with the Capacity to Reject Tumor Cells Are Generated But Fail to Migrate to Tumor Sitesin IFN-γ-deficient Mice (2001) (87)
- Molecular mechanisms underlying IFN-γ-mediated tumor growth inhibition induced during tumor growth inhibition induced during tumor immunotherapy with rIL-12 (1996) (87)
- Soluble factors involved in B cell differentiation: identification of two distinct T cell-replacing factors (TRF). (1983) (87)
- Hapten-specific IgE antibody responses in mice. I. Secondary IgE responses in irradiated recipients of syngeneic primed spleen cells. (1973) (83)
- Cellular site of action of various adjuvants in antibody responses to hapten-carrier conjugates. (1973) (83)
- The augmentation of in vitro and in vivo tumor-specific T cell-mediated immunity by amplifier T lymphocytes. (1980) (82)
- A novel function of Valpha14+CD4+NKT cells: stimulation of IL-12 production by antigen-presenting cells in the innate immune system. (1999) (80)
- The occurrence of cholecystokinin-like immunoreactive neurons in the rat neostriatum: light and electron microscopic analysis (1984) (78)
- Induction of tumor-specific in vivo protective immunity by immunization with tumor antigen-pulsed antigen-presenting cells. (1989) (77)
- Tumor-bearing mice exhibit a progressive increase in tumor antigen-presenting cell function and a reciprocal decrease in tumor antigen-responsive CD4+ T cell activity. (1992) (76)
- Enhanced production of interleukin-6 in mice with type II collagen-induced arthritis. (1989) (76)
- Dynamic changes in the mobility of LAT in aggregated lipid rafts upon T cell activation (2003) (76)
- High plasma cholecystokinin levels in patients with chronic pancreatitis having abdominal pain. (1986) (74)
- An Absolute Requirement for STAT4 and a Role for IFN-γ as an Amplifying Factor in IL-12 Induction of the Functional IL-18 Receptor Complex1 (2001) (74)
- Induction of B cell differentiation by T cell factors. I. Stimulation of IgM secretion by products of a T cell hybridoma and a T cell line. (1981) (71)
- Autoimmune thyroiditis induced in mice depleted of particular T cell subsets. I. Requirement of Lyt-1 dull L3T4 bright normal T cells for the induction of thyroiditis. (1988) (71)
- IL-12 produced by antigen-presenting cells induces IL-2-independent proliferation of T helper cell clones. (1996) (70)
- Immunologic abnormality in NZB/NZW F1 mice. Thymus-independent occurrence of B cell abnormality and requirement for T cells in the development of autoimmune disease, as evidenced by an analysis of the athymic nude individuals. (1988) (70)
- Fusogenic liposomes efficiently deliver exogenous antigen through the cytoplasm into the MHC class I processing pathway (2000) (69)
- Purification and physicochemical characterization of murine T cell replacing factor (TRF). (1985) (69)
- Enhanced production of IL-6 in tumor-bearing mice and determination of cells responsible for its augmented production. (1990) (69)
- Enhanced induction of very late antigen 4/lymphocyte function-associated antigen 1-dependent T-cell migration to tumor sites following administration of interleukin 12. (1997) (67)
- Expression of an inducible type of nitric oxide (NO) synthase in the thymus and involvement of NO in deletion of TCR-stimulated double-positive thymocytes. (1997) (66)
- A role of interferon-gamma (IFN-gamma) in tumor immunity: T cells with the capacity to reject tumor cells are generated but fail to migrate to tumor sites in IFN-gamma-deficient mice. (2001) (65)
- Multiple Roles of Interferon-γ in the Mediation of Interleukin 12-induced Tumor Regression (1998) (64)
- Distribution, origin, and fine structures of cholecystokinin-8-like immunoreactive terminals in the nucleus ventromedialis hypothalami of the rat (1984) (62)
- IL‐12‐induced tumor regression correlates with in situ activity of IFN‐γ produced by tumor‐infiltrating cells and its secondary induction of anti‐tumor pathways (1997) (60)
- Expression of VLA-4 on thymocytes. Maturation stage-associated transition and its correlation with their capacity to adhere to thymic stromal cells. (1992) (58)
- Role of glycosaminoglycans in the regulation of T cell proliferation induced by thymic stroma-derived T cell growth factor. (1991) (57)
- Molecular mechanisms underlying IFN-gamma-mediated tumor growth inhibition induced during tumor immunotherapy with rIL-12. (1996) (57)
- Tolerance induction of allo-class II H-2 antigen-reactive L3T4+ helper T cells and prolonged survival of the corresponding class II H-2-disparate skin graft. (1989) (56)
- CD9-mediated costimulation of TCR-triggered naive T cells leads to activation followed by apoptosis. (1997) (56)
- Phenotypically and functionally distinct T-cell subsets in anti-tumor responses. (1987) (56)
- A fundamental difference in the capacity to induce proliferation of naive T cells between CD28 and other co‐stimulatory molecules (1998) (56)
- Translocation of tyrosine-phosphorylated TCRzeta chain to glycolipid-enriched membrane domains upon T cell activation. (1999) (56)
- Reduction of Glycosphingolipid Levels in Lipid Rafts Affects the Expression State and Function of Glycosylphosphatidylinositol-anchored Proteins but Does Not Impair Signal Transduction via the T Cell Receptor* (2003) (55)
- B cells regulate CD40 ligand-induced IL-12 production in antigen-presenting cells (APC) during T cell/APC interactions. (1997) (54)
- Protection from anti-TCR/CD3-induced apoptosis in immature thymocytes by a signal through thymic shared antigen-1/stem cell antigen-2 (1996) (53)
- A pivotal role for CC chemokine receptor 5 in T-cell migration to tumor sites induced by interleukin 12 treatment in tumor-bearing mice. (2002) (53)
- Hapten-specific IgE antibody responses in mice. IV. Evidence for distinctive sensitivities of IgE and IgG B lymphocytes to the regulatory influence of T cells. (1974) (52)
- IMMUNOLOGICAL TOLERANCE IN BONE MARROW-DERIVED LYMPHOCYTES III. TOLERANCE INDUCTION IN PRIMED B CELLS BY HAPTEN CONJUGATES OF UNRELATED IMMUNOGENIC OR NONIMMUNOGENIC CARRIERS (1974) (52)
- Studies on the induction of tolerance to alloantigens. II. The generation of serum factor(s) able to transfer alloantigen-specific tolerance for delayed-type hypersensitivity by portal venous inoculation with allogeneic cells. (1986) (52)
- Association of a tetraspanin CD9 with CD5 on the T cell surface: role of particular transmembrane domains in the association. (1999) (51)
- A critical role for a peritumoral stromal reaction in the induction of T-cell migration responsible for interleukin-12-induced tumor regression. (1999) (51)
- Regulation of B-cell differentiation: interactions of factors and corresponding receptors. (1986) (51)
- A critical role for IL‐12 in CCR5 induction on T cell receptor‐triggered mouse CD4+ and CD8+ T cells (2001) (51)
- Radioresistance of carrier-specific helper thymus-derived lymphocytes in mice. (1972) (50)
- Modulation of TCR-mediated signaling pathway by thymic shared antigen-1 (TSA-1)/stem cell antigen-2 (Sca-2). (1995) (50)
- Inhibition of Growth and Metastasis of Ovarian Carcinoma by Administering a Drug Capable of Interfering with Vascular Endothelial Growth Factor Activity (1996) (49)
- The augmentation of tumor‐specific immunity by virus help. II. Enhanced induction of cytotoxic T lymphocyte and antibody responses to tumor antigens by vaccinia virus‐reactive helper T cells (1984) (48)
- Induction of Insulitis by Adoptive Transfer With L3T4+ Lyt2− T-Lymphocytes in T-Lymphocyte–Depleted NOD Mice (1988) (48)
- Selective suppression of t‐cell activity in tumor‐bearing mice and its improvement by lentinan, a potent anti‐tumor polysaccharide (1976) (48)
- A pivotal role of cysteine 3 of Lck tyrosine kinase for localization to glycolipid-enriched microdomains and T cell activation. (2001) (48)
- Direct suppression of TCR-mediated activation of extracellular signal-regulated kinase by leukocyte protein tyrosine phosphatase, a tyrosine-specific phosphatase. (1999) (46)
- Regulatory functions of hapten-reactive helper and suppressor T lymphocytes. III. Amplification of a generation of tumor-specific killer T-lymphocyte activities by suppressor T-cell-depleted hapten- reactive T lymphocytes (1979) (45)
- Requirement for IFN-γ in IL-12 production induced by collaboration between Vα14+ NKT cells and antigen-presenting cells (2000) (45)
- IL-12 as Well as IL-2 Upregulates CCR5 Expression on T Cell Receptor-Triggered Human CD4+ and CD8+ T Cells (2001) (44)
- A Mandatory Role for STAT4 in IL-12 Induction of Mouse T Cell CCR51 (2001) (43)
- Enhanced TNP-reactive helper T cell activity and its utilization in the induction of amplified tumor immunity that results in tumor regression. (1984) (43)
- Establishment of an IL‐12‐responsive T cell clone: its characterization and utilization in the quantitation of IL‐12 activity (1997) (42)
- Establishment of highly specific radioimmunoassays for neurokinin A and neurokinin B and determination of tissue distribution of these peptides in rat central nervous system (1989) (42)
- Ig RNA expression in normal B cells stimulated with anti-IgM antibody and T cell-derived growth and differentiation factors (1984) (41)
- Transforming Growth Factor‐β CD4+ T cells Tumor‐bearing state Immunosuppression Enhanced Production of TGF‐β and a Progressive Increase in TGF‐β Susceptibility of Anti‐tumor CD4+ T Cell Function (1993) (41)
- Hapten-specific IgE antibody responses in mice. 3. Establishment of parameters for generation of helper T cell function regulating the primary and secondary responses of IgE and IgG B lymphocytes. (1974) (40)
- Low plasma cholecystokinin response after ingestion of a test meal in patients with chronic pancreatitis. (1985) (40)
- Differentiation of thymocytes from CD3-CD4-CD8- through CD3-CD4-CD8+ into more mature stages induced by a thymic stromal cell clone. (1990) (40)
- Activation-induced expression of thymic shared antigen-1 on T lymphocytes and its inhibitory role for TCR-mediated IL-2 production. (1994) (39)
- The requirement of Ia-positive accessory cells for the induction of hapten-reactive cytotoxic T lymphocytes in vitro. (1979) (39)
- The mechanism of tumor growth inhibition by tumor-specific Lyt-1+2-T cells. I. Antitumor effect of Lyt-1+2-T cells depends on the existence of adherent cells. (1985) (38)
- Role of the thymus in repopulating alloantigen-reactive T cells after its functional elimination by intravenous presensitization with allogeneic cells. (1991) (37)
- Requirement for distinct Janus kinases and STAT proteins in T cell proliferation versus IFN-gamma production following IL-12 stimulation. (1998) (37)
- Cellular and Molecular Mechanisms Underlying IL‐12‐Induced Tumor Regression (1996) (36)
- Differential requirements for JAK2 and TYK2 in T cell proliferation and IFN‐γ production induced by IL‐12 alone or together with IL‐18 (2003) (36)
- Molecular Mechanisms Underlying Differential Contribution of CD28 Versus Non-CD28 Costimulatory Molecules to IL-2 Promoter Activation1 (2002) (35)
- Studies on macrophage-activating factor (MAF) in antitumor immune responses. I. Tumor-specific Lyt-1+2- T cells are required for producing MAF able to generate cytolytic as well as cytostatic macrophages. (1985) (35)
- The augmentation of tumor‐specific immunity by virus help. I. Demonstration of vaccinia virus‐reactive helper T cell activity involved in enhanced induction of cytotoxic T lymphocyte and antibody responses (1984) (35)
- Autoimmune thyroiditis induced in mice depleted of particular T cell subsets. III. Analysis of regulatory cells suppressing the induction of thyroiditis. (1990) (35)
- A novel vaccine delivery system using immunopotentiating fusogenic liposomes. (1999) (34)
- Potentiation of helper T cell function in IgE antibody responses by bacterial lipolysaccharide (LPS). (1974) (34)
- Antitumor and antimetastatic effects of interleukin 12 (1996) (33)
- Establishment of a tumor-specific immunotherapy model utilizing TNP-reactive helper T cell activity and its application to the autochthonous tumor system. (1984) (33)
- Inactivation of mitogen-activated protein kinases by a mammalian tyrosine-specific phosphatase, PTPBR7. (1999) (33)
- Induction of immunological tolerance in bone marrow-derived lymphocytes of the IgE antibody class. (1973) (32)
- B cell response pathways regulated by IL-5 and IL-2. Secretory microH chain-mRNA and J chain mRNA expression are separately controlled events. (1989) (31)
- Polyclonal B cell activation by a B cell differentiation factor, B151-TRF2. III. B151-TRF2 as a B cell differentiation factor closely associated with autoimmune disease. (1987) (30)
- Small and large B cells respond differently to T cell-derived B cell growth and differentiation factors. (1985) (30)
- Particular types of tumor cells have the capacity to convert transforming growth factor beta from a latent to an active form. (1992) (30)
- Antibody production in mice: IV. The suppressive effect of anti-hapten and anti-carrier antibodies on the recognition of hapten-carrier conjugate in the secondary response (1971) (29)
- Studies on the induction of tolerance to alloantigens. III. Induction of antibodies directed against alloantigen-specific delayed-type hypersensitivity T cells by a single injection of allogeneic lymphocytes via portal venous route. (1988) (29)
- The Activation of L3T4+ Helper T Cells Assisting the Generation of Anti‐Tumor Lyt‐2+ Cytotoxic T Lymphocytes: Requirement of 1a‐Positive Antigen‐Presenting Cells for Processing and Presentation of Tumor Antigens (1987) (28)
- Evidence for the functional binding in vivo of tumor rejection antigens to antigen-presenting cells in tumor-bearing hosts. (1991) (28)
- Regulatory mechanisms of antitumor T cell responses in the tumor-bearing state (1995) (28)
- Antigen-induced T cell-replacing factor (TRF). II. X-linked gene control for the expression of TRF-acceptor site(s) on B lymphocytes and preparation of specific antiserum to that acceptor. (1980) (28)
- Helper strategy in tumor immunology: Expansion of helper lymphocytes and utilization of helper lymphokines for experimental and clinical immunotherapy (1988) (28)
- Serine 6 of Lck Tyrosine Kinase: A Critical Site for Lck Myristoylation, Membrane Localization, and Function in T Lymphocytes1 (2000) (28)
- Induction of surface CCR4 and its functionality in mouse Th2 cells is regulated differently during Th2 development (2005) (28)
- A novel immunization procedure for production of anti-cholecystokinin-specific antiserum of low cross-reactivity. (1981) (28)
- IL‐12 plays a pivotal role in LFA‐1‐mediated T cell adhesiveness by up‐regulation of CCR5 expression (2001) (27)
- The role of tumor-specific Lyt-1+2− T cells in eradicating tumor cells in vivo (1987) (27)
- DBA/2Ha Mice as a Model of an X‐Linked Immunodeficiency which is Defective in the Expression of TRF‐Acceptor Site(s) on B Lymphocytes (1982) (26)
- A mechanism underlying STAT4‐mediated up‐regulation of IFN‐γ induction inTCR‐triggered T cells (2004) (26)
- IMMUNOLOGICAL TOLERANCE IN BONE MARROW-DERIVED LYMPHOCYTES : II. EFFECTS OF ALLOGENEIC CELL INTERACTIONS AND ENZYMATIC DIGESTION WITH TRYPSIN ON INACTIVATED HAPTEN-SPECIFIC PRECURSORS OF ANTIBODY-FORMING CELLS (1974) (26)
- Heterogenous graft rejection pathways in class I major histocompatibility complex-disparate combinations and their differential susceptibility to immunomodulation induced by intravenous presensitization with relevant alloantigens (1991) (25)
- HAPTEN-SPECIFIC IgE ANTIBODY RESPONSES IN MICE (1973) (25)
- Regulatory functions of hapten-reactive helper and suppressor T lymphocytes. I. Detection and characterization of hapten-reactive suppressor T-cell activity in mice immunized with hapten-isologous protein conjugate (1977) (25)
- Characterization of an immune response gene in mice controlling IgE and IgG antibody responses to ragweed pollen extract and its 2,4‐dinitrophenylated derivative (1974) (24)
- Coordination of chemokine and adhesion systems in intratumoral T cell migration responsible for the induction of tumor regression. (2001) (24)
- CD5 Costimulation Up-Regulates the Signaling to Extracellular Signal-Regulated Kinase Activation in CD4+CD8+ Thymocytes and Supports Their Differentiation to the CD4 Lineage1 (2000) (24)
- A sequence of cellular and molecular events involved in IL12-induced tumour regression. (1995) (23)
- TOLERANCE INDUCTION OF ALLOREACTIVITY BY PORTAL VENOUS INOCULATION WITH ALLOGENEIC CELLS FOLLOWED BY THE INJECTION OF CYCLOPHOSPHAMIDE: I. SPECIFIC SUPPRESSION OF ALLOREACTIVE CYTOTOXIC AND DELAYED‐TYPE HYPERSENSITIVITY RESPONSES AS WELL AS ALLOGRAFT REJECTION (1987) (23)
- Mechanism of adjuvant activity of poly A:U on antibody responses to hapten-carrier conjugates. (1973) (23)
- Thymic stroma-derived T cell growth factor (TSTGF). I. Functional distinction of TSTGF from interleukins 2 and 4 and its preferential growth-promoting effect on helper T cell clones. (1987) (23)
- SCID (severe combined immunodeficiency) mice as a new system to investigate metastasis of human tumors. (1990) (23)
- Developmentally regulated expression of a murine receptor-type protein tyrosine phosphatase in the thymus. (1994) (22)
- Identification of IL-7-dependent bone marrow-derived Thy-1-B220- lymphoid cell clones that rearrange and express both Ig and T cell receptor genes. (1992) (22)
- Multiple roles of interferon-gamma in the mediation of interleukin 12-induced tumor regression. (1998) (22)
- cDNA cloning of a novel protein tyrosine phosphatase with homology to cytoskeletal protein 4.1 and its expression in T-lineage cells. (1994) (22)
- Cholecystokinin-8-like immunoreactivity in the pre- and post-central gyri of the human cerebral cortex (1984) (22)
- CD28 costimulation is required not only to induce IL‐12 receptor but also to render Janus kinases / STAT4 responsive to IL‐12 stimulation in TCR‐triggered T cells (2001) (21)
- Immune Dysfunction Expressed Selectively on L3T4+ T Cells in the Tumor‐Bearing State (1990) (21)
- CD28 co-stimulatory signals induce IL-2 receptor expression on antigen-stimulated virgin T cells by an IL-2-independent mechanism. (1996) (20)
- Property of class I H-2 alloantigen-reactive Lyt-2+ helper T cell subset. Abrogation of its proliferative and IL-2-producing capacities by intravenous injection of class I H-2-disparate allogeneic cells. (1988) (20)
- Rapid Growth and Spontaneous Metastasis of Human Germinal Tumors Ectopically Transplanted into Scid (Severe Combined Immunodeficiency) and Scid‐nudestreaker Mice (1991) (20)
- Heterogeneity of CD4+ T cells involved in anti-allo-class I H-2 immune responses. Functional discrimination between the major proliferating cells and helper cells assisting cytotoxic T cell responses. (1991) (19)
- IFN-α Acts on T-Cell Receptor-Triggered Human Peripheral Leukocytes to Up-Regulate CCR5 Expression on CD4+ and CD8+ T Cells (2001) (19)
- Antibody production in mice. I. The analysis of immunological memory. (1969) (19)
- Cyclosporin A inhibits late steps of T lymphocyte activation after transmembrane signaling. (1987) (18)
- B cell-mediated down-regulation of IFN-gamma and IL-12 production induced during anti-tumor immune responses in the tumor-bearing state. (1998) (18)
- Capacities of a Newly Established Thymic Stromal Cell Clone to Express la Antigens and to Produce Interleukin‐6, Colony‐Stimulating Factor, and Thymic Stroma‐Derived T‐Cell Growth Factor (1989) (18)
- The mechanism of tolerance induction in thymus-derived lymphocytes; I. intracellular inactivation of hapten-reactive helper T lymphocytes by hapten-nonimmunogenic copolymer of D-amino acids (1975) (18)
- Requirement for IFN-gamma in IL-12 production induced by collaboration between v(alpha)14(+) NKT cells and antigen-presenting cells. (2000) (18)
- Ontogeny of neuropeptides in the nucleus ventromedialis hypothalami of the rat: an immunohistochemical analysis. (1984) (18)
- The augmentation of tumor-specific immunity by virus help (1986) (18)
- Murine tumor cell lysis by antibody-dependent macrophage-mediated cytotoxicity using syngeneic monoclonal antibodies. (1985) (17)
- Development and Recognition of the Transformed Cell (1987) (17)
- Augmented induction of tumor-specific resistance by priming with Mycobacterium tuberculosis (TBC) and subsequent immunization with PPD-coupled syngeneic tumor cells. (1980) (17)
- Do Structural Changes of T Cell Receptor Complex Occur in Tumor‐bearing State? (1995) (17)
- Thymic stroma-derived T cell growth factor (TSTGF). IV. Capacity of TSTGF to promote the growth of L3T4- Lyt-2- thymocytes by synergy with phorbol myristate acetate or various IL. (1989) (17)
- Identification of two distinct factors, B151-TRF1 and B151-TRF2, inducing differentiation of activated B cells and small resting B cells into antibody-producing cells. (1986) (17)
- Type II collagen-induced murine arthritis: induction of arthritis depends on antigen-presenting cell function as well as susceptibility of host to an anticollagen immune response. (1992) (17)
- Induction of anti-allo-class I H-2 tolerance by inactivation of CD8+ helper T cells, and reversal of tolerance through introduction of third- party helper T cells (1990) (16)
- IMMUNOLOGICAL TOLERANCE IN BONE MARROW-DERIVED LYMPHOCYTES (1974) (16)
- Anti–HER-2/neu Immune Responses Are Induced before the Development of Clinical Tumors but Declined following Tumorigenesis in HER-2/neu Transgenic Mice (2004) (16)
- IL-5 up-regulates but IL-4 down-regulates IL-2R expression on a cloned B lymphoma line. (1990) (16)
- A mechanism underlying STAT4-mediated up-regulation of IFN-gamma induction inTCR-triggered T cells. (2004) (16)
- Immunoregulation in the rat: cellular and molecular requirements for B cell responses to types 1, 2, and T-dependent antigens. (1985) (15)
- An in vitro model for cyclosporin A-induced interference of intrathymic clonal elimination (1990) (15)
- Abrogation of the capacity of delayed-type hypersensitivity responses to alloantigens by intravenous injection of neuraminidase-treated allogeneic cells. (1987) (15)
- SUPPRESSION OF ALLOGRAFT RESPONSES BY COMBINING DONOR ALLOANTIGEN‐SPECIFIC INTRAVENOUS PRESENSITIZATION WITH SUBOPTIMAL DOSES OF FK506 (1993) (15)
- Instability of assembled T-cell receptor complex that is associated with rapid degradation of zeta chains in immature CD4+CD8+ thymocytes. (1992) (15)
- Preferential generation of killer or helper T-lymphocyte activity directed to the tumour-associated transplantation antigens. (1976) (15)
- Helper T cells against tumor-associated antigens (TAA): preferential induction of helper T cell activities involved in anti-TAA cytotoxic T lymphocyte and antibody responses. (1986) (15)
- Immunologic characterization of tumor-associated transplantation antigens on MM102 mammary tumor eliciting preferentially helper T cell activity. (1978) (15)
- Differential IL-12 responsiveness of T cells but not of NK cells from tumor-bearing mice in IL-12-responsive versus -unresponsive tumor models. (2000) (14)
- [Immunological memory cells]. (1969) (14)
- A role for endogenous IL‐12 in tumor immunity: IL‐12 is required for the acquisition of tumor‐migratory capacity by T cells and the development of T cell‐accepting capacity in tumor masses (2002) (14)
- Antibody against T cell-replacing factor acceptor site(s) augments in vivo primary IgM responses to suboptimal doses of heterologous erythrocytes (1981) (14)
- Selective elimination of a B cell subset having acceptor site(s) for T cell-replacing factor (TRF) with biotinylated antibody to the acceptor site(s) and avidin-ricin A-chain conjugate. (1984) (14)
- Tolerance Induction of Alloreactivity by Portal Venous Inoculation with Allogeneic Cells Followed by the Injection of Cyclophosphamide (1988) (14)
- Functional characterization of the killer-helper factor responsible for the induction of cytotoxic T lymphocytes from thymocytes, and evidence for the nature of this factor as distinct from T cell-replacing factor (TRF) in regard to B cell triggering. (1981) (13)
- Establishment of three PPD-reactive helper T cell clones with distinct functions in B cell activation. (1984) (13)
- Requirements of adherent cells for activating Lyt-1+2- T cells as well as for functioning as antitumor effectors activated by factor(s) from Lyt-1+2- T cells. (1986) (13)
- The anti-tumor effects of IL-12 involve enhanced IFN-gamma production by anti-tumor T cells, their accumulation to tumor sites and in situ IFN-gamma production. (1997) (13)
- Cell interactions between histoincompatible T and B lymphocytes. V. Failure of histoincompatible T cells to interfere with physiologic cooperation between syngeneic T and B lymphocytes. (1974) (13)
- Pre-B cells adhere to fibronectin via interactions of integrin α5/αv with RGDS as well as of integrin α4 with two distinct V region sequences at its different binding sites (1994) (13)
- Expression of H-2 antigens and inducibility of antitumor immune responses in various tumor cell clones established from methylcholanthrene-induced fibrosarcomas. (1986) (13)
- High plasma cholecystokinin response following ingestion of test meal by patients with non-insulin dependent diabetes mellitus (1986) (13)
- Generation of cytotoxic T lymphocytes from thymocyte precursors to trinitrophenyl-modified self antigens. I. Requirement of both killer-helper factor(s) and interleukin 2 for CTL generation from a subpopulation of thymocytes. (1986) (13)
- IFN-alpha acts on T-cell receptor-triggered human peripheral leukocytes to up-regulate CCR5 expression on CD4+ and CD8+ T cells. (2001) (13)
- Detection and characterization of idiotype-specific enhancing cells generated in mice immunized with idiotype. (1982) (13)
- T-T cell interaction in the induction of delayed-type hypersensitivity (DTH) responses: vaccinia virus-reactive helper T cell activity involved in enhanced in vivo induction of DTH responses and its application to augmentation of tumor-specific DTH responses. (1985) (13)
- Regulatory functions of hapten-reactive helper and suppressor T lymphocytes. II. Selective inactivation of hapten-reactive suppressor T cells by hapten-nonimmunogenic copolymers of D-amino acids, and its application to the study of suppressor T-cell effect on helper T-cell development (1977) (13)
- THE LYMPHOID CELL POPULATIONS REQUIRED FOR INDUCTION OF TOLERANCE OF DIFFERENT SUBSETS OF ALLOANTIGEN‐REACTIVE T CELLS (1991) (12)
- Synergy between CD28 and CD9 costimulation for naive T-cell activation. (1997) (12)
- Direct recognition of rat MHC antigens on rat antigen-presenting cells by mouse CD4+ and CD8+ T cells and establishment of T cell clones exhibiting a direct recognition pathway. (1997) (12)
- Enhanced induction of tumor-specific Lyt-1+2- T cell-mediated protective immunity by in vivo administration of interleukin 1. (1985) (12)
- Localization of PTP-FERM in nerve processes through its FERM domain. (2002) (11)
- Autoimmune thyroiditis induced in mice depleted of particular T cell subsets. II. Immunohistochemical studies on the thyroiditis lesion. (1989) (11)
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- Selective suppression of host T cell and macrophage activities during 7,12-dimethylbenz[a]anthracene-induced carcinogenesis. (1982) (10)
- Inhibitory effect of tumor-bearing state on the generation of in vivo protective immune T cells in a syngeneic murine tumor system. (1977) (10)
- Immune maturation of T lymphocytes: sequential changes in the functional specificity and apparent affinity of hapten-reactive helper T cells during an immune response. (1976) (10)
- Effector cell analysis of tumor cell rejection in vivo in two syngeneic tumor systems exhibiting distinct in vitro cytotoxic mechanisms. (1984) (10)
- Characterization of defectiveness in endogenous antigen presentation of novel murine cells established from methylcholanthrene-induced fibrosarcomas. (1995) (10)
- The role of anti-asialo GM1 antibody-sensitive cells in the implementation of tumor-specific T cell-mediated immunity in vivo. (1986) (10)
- Antibody production in mice. V. The suppressive effect of anti-carrier antibodies on cellular cooperation in the induction of secondary anti-hapten antibody responses. (1973) (10)
- Mediation of in vivo Tumor‐neutralizing Activity by Lyt‐2+ as Well as L3T4+ T Cell Subsets*1 (1988) (10)
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- Acceptor site(s) for T cell-replacing factor (TRF) on B lymphocytes. I. TRF-substituting activity of anti-TRF acceptor site(s) antibody in the triggering of B cells. (1982) (9)
- Role of a thymic stromal cell clone in inducing the stage-specific differentiation of various subpopulations of double negative thymocytes. (1991) (9)
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- Administration of IL-12 induces a CD3+ CD4- CD8- B220+ lymphoid population capable of eliciting cytolysis against Fas-positive tumor cells. (1997) (9)
- Cell-cell interaction in graft rejection responses: induction of anti- allo-class I H-2 tolerance is prevented by immune responses against allo-class II H-2 antigens coexpressed on tolerogen (1992) (8)
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- Model for clonal elimination in the thymus. (1989) (8)
- A caspase inhibitor protects thymocytes from diverse signal-mediated apoptosis but not from clonal deletion in fetal thymus organ culture. (1998) (8)
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- Involvement of I-A-restricted B-B cell interaction in the polyclonal B cell differentiation induced by lipopolysaccharide. (1990) (7)
- Cluster formation among small resting B lymphocytes leading to B cell activation. (1989) (7)
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- Immunological Properties of Fc Receptor on Lymphocytes (1981) (6)
- II. FAILURE OF PHYSIOLOGIC COOPERATIVE INTERACTIONS BETWEEN T AND B LYMPHOCYTES ~ROM ALLOGENEIC DONOR STRAINS IN HUMORAL RESPONSE TO HAPTEN-PROTEIN CONJUGATES* (1973) (6)
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- Selective expression of paternal human major histocompatibility antigens on the surface of hydatidiform mole cells. (1978) (6)
- Acceptor site(s) for T cell-replacing factor (TRF) on B lymphocytes. II. Activation of B cells by cross-linkage or aggregation of the TRF acceptor molecule. (1982) (6)
- B cell growth and differentiation activity of a purified T cell-replacing factor (TRF) molecule from B151-T cell hybridoma. (1985) (6)
- Identification and characterization of IL-2 hyper-responsive NZB/WF1 CD5- B cells. (1994) (6)
- Distribution of neuropeptides in the hypothalamo-hypophyseal system in the rat: an immunohistochemical observation. (1984) (6)
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- B-B cell interaction involved in polyclonal B cell activation is restricted by I-A but not by I-E molecules. (1990) (6)
- Suppression of allograft responses by combining alloantigen-specific i.v. pre-sensitization with suboptimal doses of rapamycin. (1994) (6)
- Cellular mechanisms of tumor rejection in vivo and enhanced induction of anti tumor protective immunity applicable to tumor-specific immunotherapy. (1988) (5)
- Proliferation and differentiation of immature thymocytes induced by a thymic stromal cell clone. (1990) (5)
- Prophylactic effect of BCG cell-wall skeleton on the tumor induction by 7,12-dimethylbenz[a]anthracene in mice: strain difference. (1979) (5)
- Subunit composition of the pre‐T‐cell receptor complex analysed by monoclonal antibody against the pre‐T‐cell receptor α chain (1997) (5)
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- T‐T Cell Interaction in the In Vitro Induction of Delayed‐Type Hypersensitivity (DTH) Responses: Demonstration of Vaccinia Virus‐Reactive Helper T Cell Activity Involved in Enhanced Induction of DTH Responses (1985) (5)
- Marked depression of brain cholecystokinin and vasoactive intestinal polypeptide levels in Eck fistula dogs (1989) (5)
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- Interleukin-1 restores the impaired cytotoxic T lymphocyte generation in beige mutant mouse. (1984) (5)
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- Suppressive versus augmenting effect of the same pretreatment regimen in two murine tumor systems with distinct effector mechanisms. (1978) (5)
- Type II collagen-induced murine arthritis. II. Genetic control of arthritis induction is expressed on L3T4+ T cells required for humoral as well as cell-mediated immune responses to type II collagen. (1989) (5)
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- T-cell-derived factor B151-TRF1/IL-5 activates blastoid cells among unprimed B cells to induce a polyclonal differentiation into immunoglobulin M-secreting cells. (1988) (5)
- Thymic stromal cells eliminate T cells stimulated with antigen plus stromal Ia molecules through their cross-talk involving the production of interferon-gamma and nitric oxide. (1994) (5)
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- The generation of tumor-specific in vivo protective immunity in the tumor mass from mice rendered tolerant to tumor antigens (2004) (0)
- Effect of Passive Administration of Alloantiserum Containing Antibody against Putative Acceptor(s) for T Cell‐Replacing Factor (TRF) in the Neonatal Stage on Development of B Cell Activity Responsive to TRF (1986) (0)
- [The role of hapten-specific T cells in the induction of autoimmunity and immune resistance against tumor in mice (author's transl)]. (1978) (0)
- The Origin of Antibody‐Forming Cells Detected in the Bone Marrow after Thymus‐Independent Antigen‐Stimulation and Abnormality in Migration of B Cells of X‐Linked Immunodeficient CBA/N Mice (1987) (0)
- IV. INVOLVEMENT O~' TIlE )~MMUNE RESPONSE (Ir) GENt: IN THE CONTROL OF LYMPHOCYTE INTERACTIONS IN RESPONSES CONTROLLED BS~ TIlE GENE* (1973) (0)
- Activation Costimulatory Molecules to IL-2 Promoter Contribution of CD28 Versus Non-CD28 Molecular Mechanisms Underlying Differential (2011) (0)
- A novel immunization procedure involving pretreatment with cross-reacting steroid conjugated to a copolymer of D-glutamic acid and D-lysine for production of low cross-reactive antisera. (1980) (0)
- Identification of a B cell subset responsive to a T cell-derived lymphokine B151-TRF2 by monoclonal antibody specific for N-acetylglucosamine residue(S) (1988) (0)
- InductionofAnti-Allo-Class IH-2 Toleranceby Inactivation ofCD8 + HelperT Cells,and Reversal ofTolerancethroughIntroductionofThird-Party (1990) (0)
- A human glioma cell line of a positive immunostaining for somatostatin (1983) (0)
- Suppressive Effect of Ultraviolet‐B‐Irradiation of Epidermal Cells on the Induction of Contact Sensitivity (1986) (0)
- and Produce IFN- T Cell Subsets to Express IL-18 Receptor - CD8 - Differential Capacities of CD4+, CD8+, and CD4 (2013) (0)
- [Tumor-specific immunotherapy: active immunotherapy by augmenting the induction of tumor-specific effector T cells through a T-T cell interaction mechanism]. (1984) (0)
- TRF-RESPONSIVE B CELLS CONSTITUTE A SUBPOPULATION DISTINCT FROM THE OTHER B CELL SUBPOPULATION (1982) (0)
- Establishment of murine macrophage hybridoma clones capable of acquiring tumoricidal activity upon activation with recombinant interferon-γ and lipopolysaccharide (2004) (0)
- Antibody response of the tumor-bearing animals. (1965) (0)
- Immunochemical studies on taka-amylase A. Kinetic studies on the inhibition of amylase activity by anti-taa antibody. (1967) (0)
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What Schools Are Affiliated With Toshiyuki Officer Resi Hamaoka?
Toshiyuki Officer Resi Hamaoka is affiliated with the following schools: