Timothy John Chambers
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Biology
Timothy John Chambers's Degrees
- PhD Cell Biology University of California, Berkeley
- Masters Biochemistry Stanford University
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(Suggest an Edit or Addition)Timothy John Chambers's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- TRANCE Is Necessary and Sufficient for Osteoblast-mediated Activation of Bone Resorption in Osteoclasts (1998) (592)
- Calcitonin alters behaviour of isolated osteoclasts (1982) (524)
- Tumor necrosis factors alpha and beta induce osteoblastic cells to stimulate osteoclastic bone resorption. (1987) (514)
- A crucial role for thiol antioxidants in estrogen-deficiency bone loss. (2003) (502)
- Resorption of bone by isolated rabbit osteoclasts. (1984) (439)
- Osteoblastic cells mediate osteoclastic responsiveness to parathyroid hormone. (1986) (419)
- The effect of calcium-regulating hormones and prostaglandins on bone resorption by osteoclasts disaggregated from neonatal rabbit bones. (1985) (414)
- Osteoblasts mediate interleukin 1 stimulation of bone resorption by rat osteoclasts (1986) (394)
- Interleukin-18 (interferon-gamma-inducing factor) is produced by osteoblasts and acts via granulocyte/macrophage colony-stimulating factor and not via interferon-gamma to inhibit osteoclast formation. (1997) (381)
- Macrophage colony-stimulating factor stimulates survival and chemotactic behavior in isolated osteoclasts (1993) (351)
- Regulation of the differentiation and function of osteoclasts (2000) (329)
- Fosl1 is a transcriptional target of c-Fos during osteoclast differentiation (2000) (316)
- Hydrogen peroxide is essential for estrogen-deficiency bone loss and osteoclast formation. (2005) (304)
- Osteoblast-like cells in the presence of parathyroid hormone release soluble factor that stimulates osteoclastic bone resorption. (1986) (301)
- Monoclonal antibodies to osteoclastomas (giant cell bone tumors): definition of osteoclast-specific cellular antigens. (1985) (299)
- TNFα Potently Activates Osteoclasts, through a Direct Action Independent of and Strongly Synergistic with RANKL. (2002) (296)
- Estrogen maintains trabecular bone volume in rats not only by suppression of bone resorption but also by stimulation of bone formation. (1992) (268)
- The pathobiology of the osteoclast. (1985) (256)
- Bone cells predispose bone surfaces to resorption by exposure of mineral to osteoclastic contact. (1985) (230)
- Induction of NO and prostaglandin E2 in osteoblasts by wall-shear stress but not mechanical strain. (1997) (228)
- Inhibition of colony-stimulating-factor-1 signaling in vivo with the orally bioavailable cFMS kinase inhibitor GW2580. (2005) (221)
- Increased insulin-like growth factor I mRNA expression in rat osteocytes in response to mechanical stimulation. (1995) (212)
- 1,25-Dihydroxyvitamin D3 stimulates rat osteoblastic cells to release a soluble factor that increases osteoclastic bone resorption. (1987) (205)
- Nitric oxide is an early mediator of the increase in bone formation by mechanical stimulation. (1996) (192)
- A role for TGFbeta(1) in osteoclast differentiation and survival. (2000) (189)
- The sensitivity of isolated osteoclasts to morphological transformation by calcitonin. (1983) (186)
- Dichloromethylenebisphosphonate (Cl2MBP) inhibits bone resorption through injury to osteoclasts that resorb Cl2MBP-coated bone. (1989) (180)
- Induction of bone formation in rat tail vertebrae by mechanical loading. (1993) (172)
- The multinucleate cells in giant cell granulomas of the jaw are osteoclasts (1988) (168)
- Calcitonin receptors as markers for osteoclastic differentiation: correlation between generation of bone-resorptive cells and cells that express calcitonin receptors in mouse bone marrow cultures. (1989) (163)
- Generation of osteoclast-inductive and osteoclastogenic cell lines from the H-2KbtsA58 transgenic mouse. (1993) (157)
- Indomethacin has distinct early and late actions on bone formation induced by mechanical stimulation. (1994) (149)
- CCL9/MIP‐1γ and its receptor CCR1 are the major chemokine ligand/receptor species expressed by osteoclasts (2002) (148)
- TNFalpha potently activates osteoclasts, through a direct action independent of and strongly synergistic with RANKL. (2002) (147)
- Osteocytic expression of mRNA for c-fos and IGF-I: an immediate early gene response to an osteogenic stimulus. (1996) (147)
- Effect of substrate composition on bone resorption by rabbit osteoclasts. (1984) (142)
- The effects of calcium regulating hormones on bone resorption by isolated human osteoclastoma cells (1985) (139)
- Role of Nitric Oxide and Prostaglandins in Mechanically Induced Bone Formation (1998) (130)
- Secretion of tartrate‐resistant acid phosphatase by osteoclasts correlates with resorptive behavior (2006) (130)
- Endothelin inhibits osteoclastic bone resorption by a direct effect on cell motility: implications for the vascular control of bone resorption. (1992) (128)
- Characterization of osteogenic response to mechanical stimulation in cancellous bone of rat caudal vertebrae. (1993) (127)
- Macrophage colony stimulating factor (M-CSF) is essential for osteoclast formation in vitro. (1991) (125)
- Generation of osteoclastic function in mouse bone marrow cultures: multinuclearity and tartrate-resistant acid phosphatase are unreliable markers for osteoclastic differentiation. (1989) (125)
- Angiotensin II is generated from angiotensin I by bone cells and stimulates osteoclastic bone resorption in vitro. (1997) (124)
- Mechanical Loading Stimulates Bone Formation by Reactivation of Bone Lining Cells in 13‐Week‐Old Rats (1998) (123)
- Macrophage inflammatory protein-1 alpha and IL-8 stimulate the motility but suppress the resorption of isolated rat osteoclasts. (1995) (123)
- IL-10 modulates formation of osteoclasts in murine hemopoietic cultures. (1996) (117)
- Monoclonal antibodies against osteoclasts inhibit bone resorption in vitro. (1986) (117)
- Cell surface characterization of the human osteoclast: Phenotypic relationship to other bone marrow‐derived cell types (1984) (114)
- Effect of parathyroid hormone and calcitonin on the cytoplasmic spreading of isolated osteoclasts. (1984) (111)
- Inhibition of osteoclastic motility by prostaglandins I2, E1, E2 and 6‐oxo‐E1 (1983) (111)
- Effect of arachidonic acid metabolites on bone resorption by isolated rat osteoclasts (1989) (110)
- The role of reactive oxygen intermediates in osteoclastic bone resorption. (1995) (110)
- Activin A is an essential cofactor for osteoclast induction. (2000) (108)
- Osteoblasts release osteoclasts from calcitonin-induced quiescence. (1982) (105)
- A comparison of bone mineral density between Caucasian, Asian and Afro-Caribbean women. (1994) (105)
- Cathepsin K inhibitors prevent matrix-derived growth factor degradation by human osteoclasts. (2008) (105)
- The cellular basis of bone resorption. (1980) (104)
- Stimulation of bone nodule formation in vitro by prostaglandins E1 and E2. (1992) (103)
- Colitis causes bone loss in rats through suppression of bone formation. (1996) (101)
- The estrogen antagonist ICI 182,780 reduces cancellous bone volume in female rats. (1993) (100)
- Human macrophage colony‐stimulating factor inhibits bone resorption by osteoclasts disaggregated from rat bone (1988) (99)
- Glucocorticoids impair bone resorptive activity and viability of osteoclasts disaggregated from neonatal rat long bones. (1989) (97)
- Purification and characterization of a tartrate-resistant acid phosphatase from human osteoclastomas. (1989) (96)
- Mammalian collagenase predisposes bone surfaces to osteoclastic resorption (2004) (95)
- Localisation of mRNA for collagenase in osteocytic, bone surface and chondrocytic cells but not osteoclasts. (1995) (95)
- Gallium inhibits bone resorption by a direct effect on osteoclasts. (1990) (95)
- Tumor Necrosis Factor-α Mediates Osteopenia Caused by Depletion of Antioxidants (2005) (92)
- A direct action of human calcitonin gene-related peptide on isolated osteoclasts. (1987) (92)
- Divalent cations mimic the inhibitory effect of extracellular ionised calcium on bone resorption by isolated rat osteoclasts: Further evidence for a “calcium receptor” (1991) (89)
- Role for parathyroid hormone in mechanical responsiveness of rat bone. (1998) (89)
- Effect of prostaglandins E1, E2, and F2α on osteoclast formation in mouse bone marrow cultures (1991) (89)
- Effects of peptides from the calcitonin genes on bone and bone cells. (1988) (88)
- Generation of osteoclasts in cultures of rabbit bone marrow and spleen cells (1987) (86)
- Effects of interleukin 3 and of granulocyte‐macrophage and macrophage colony stimulating factors on osteoclast differentiation from mouse hemopoietic tissue (1990) (86)
- 17 beta-estradiol stimulates cancellous bone formation in female rats. (1992) (86)
- Murine osteoclast formation and function: differential regulation by humoral agents. (2006) (85)
- Use of a bisphosphonate (pamidronate) to modulate fracture repair in ovine bone. (1994) (84)
- Tri-iodothyronine stimulates rat osteoclastic bone resorption by an indirect effect. (1992) (84)
- The Possible Role of TGF-β-Induced Suppressors of Cytokine Signaling Expression in Osteoclast/Macrophage Lineage Commitment In Vitro1 (2003) (83)
- Inflammatory giant cells. (1982) (83)
- Opposite effects of insulin-like growth factor-I on the formation of trabecular and cortical bone in adult female rats. (1992) (82)
- Interferon-gamma directly inhibits TRANCE-induced osteoclastogenesis. (2000) (82)
- Estrogen suppresses activation but enhances formation phase of osteogenic response to mechanical stimulation in rat bone. (1996) (81)
- Phagocytosis and trypsin‐resistant glass adhesion by osteoclasts in culture (1979) (81)
- Identification of osteoclast precursors in multilineage hemopoietic colonies. (1991) (79)
- Interleukin-18 (Interferon-γ–inducing Factor) Is Produced by Osteoblasts and Acts Via Granulocyte/Macrophage Colony-stimulating Factor and Not Via Interferon-γ to Inhibit Osteoclast Formation (1997) (79)
- Inhibition of bone resorption by bisphosphonates: Interactions between bisphosphonates, osteoclasts, and bone (1991) (76)
- Hormonal regulation of acid phosphatase release by osteoclasts disaggregated from neonatal rat bone (1987) (76)
- TGF-β1 and IFN-γ Direct Macrophage Activation by TNF-α to Osteoclastic or Cytocidal Phenotype1 (2000) (74)
- Estrogen does not restore bone lost after ovariectomy in the rat (1993) (73)
- Prostaglandin e2 promotes osteoclast formation in murine hematopoietic cultures through an action on hematopoietic cells (1992) (73)
- Diphosphonates inhibit bone resorption by macrophages in vitro (1980) (71)
- Effects of transforming growth factor β1 on the regulation of osteoclastic development and function (1991) (71)
- Recent developments in cathepsin K inhibitor design. (2005) (71)
- The effect of human calcitonin on the cytoplasmic spreading of rat osteoclasts. (1986) (69)
- FLT3 ligand can substitute for macrophage colony-stimulating factor in support of osteoclast differentiation and function. (2001) (64)
- Sequential analysis of gene expression after an osteogenic stimulus: c-fos expression is induced in osteocytes. (1995) (63)
- The role of prostaglandins and nitric oxide in the response of bone to mechanical forces. (1999) (62)
- The effect of hepatocyte growth factor on the behaviour of osteoclasts. (1995) (61)
- Generation of osteoclasts from hemopoietic cells and a multipotential cell line in vitro (1989) (61)
- Calcitonin gene-related peptide inhibits osteoclastic bone resorption: A comparative study (1987) (60)
- A role for TGF β 1 in osteoclast differentiation and survival (60)
- Cellular and molecular mechanisms in the regulation and function of osteoclasts. (1991) (59)
- Purification and characterization of a tripeptidyl peptidase I from human osteoclastomas: evidence for its role in bone resorption. (1993) (58)
- Osteoclast lineage commitment of bone marrow precursors through expression of membrane-bound TRANCE. (2000) (57)
- Osteoclast resorption-stimulating activity is associated with the osteoblast cell surface and/or the extracellular matrix. (1991) (55)
- How are osteoclasts induced to resorb bone? (2011) (53)
- Degradation of bone matrix proteins by osteoclast cathepsins. (1993) (52)
- Bone Is Not Essential for Osteoclast Activation (2010) (50)
- Mechanotransduction in bone cells: induction of nitric oxide and prostaglandin synthesis by fluid shear stress, but not by mechanical strain. (1997) (49)
- High concentrations of 17 beta-estradiol stimulate trabecular bone formation in adult female rats. (1991) (48)
- Tumor necrosis factor-alpha mediates osteopenia caused by depletion of antioxidants. (2005) (48)
- Human osteoclastomas contain multiple forms of cathepsin B. (1992) (47)
- Heparin augments osteoclast resorption‐stimulating activity in serum (1991) (45)
- Na+/H+ antiporter is the primary proton transport system used by osteoclasts during bone resorption (1990) (44)
- Thioredoxin-1 mediates osteoclast stimulation by reactive oxygen species. (2004) (43)
- 5 alpha-Dihydrotestosterone partially restores cancellous bone volume in osteopenic ovariectomized rats. (1994) (43)
- Osteoclast activation: Potent inhibition by the bisphosphonate alendronate through a nonresorptive mechanism (1997) (42)
- Phagocytic recognition of bone by macrophages (1981) (42)
- The regulation of osteoclastic development and function. (1988) (42)
- Activation of osteoclasts by interleukin‐1: divergent responsiveness in osteoclasts formed in vivo and in vitro (2000) (41)
- Fusion of macrophages following simultaneous attempted phagocytosis of glutaraldehyde‐fixed red cells (1977) (41)
- Structure-activity relationship of human calcitonin-gene-related peptide. (1990) (41)
- Derivation of osteoclasts from hematopoietic colony‐forming cells in culture (1992) (40)
- Regulation and enzymatic basis of bone resorption by human osteoclasts. (2007) (39)
- The effect of sex hormones on bone resorption by rat osteoclasts. (1991) (38)
- TGF-β-induced SOCS3 expression augments TNF-α-induced osteoclast formation (2003) (38)
- The effect of parathyroid hormone, 1,25‐dihydroxycholecalciferol and prostaglandins on the cytoplasmic activity of isolated osteoclastsxs (1982) (37)
- Mitf-PU.1 interactions with the tartrate-resistant acid phosphatase gene promoter during osteoclast differentiation. (2004) (37)
- Studies on the phagocytic capacity of macrophage polykaryons (1977) (37)
- Transgenic mice reveal novel sites of calcitonin receptor gene expression during development. (2000) (35)
- RoBo-1, a Novel Member of the Urokinase Plasminogen Activator Receptor/CD59/Ly-6/Snake Toxin Family Selectively Expressed in Rat Bone and Growth Plate Cartilage* (1998) (34)
- Induction of osteoclast formation by parathyroid hormone depends on an action on stromal cells. (1998) (34)
- Bone cells required for osteoclastic resorption but not for osteoclastic differentiation. (1996) (34)
- Tartrate-resistant acid phosphatase from human osteoclastomas is translated as a single polypeptide. (1991) (33)
- Automated three‐dimensional characterization of osteoclastic resorption lacunae by stereoscopic scanning electron microscopy (1994) (32)
- Macrophage colony-stimulating factor (M-CSF) induces migration in osteoclasts in vitro. (1993) (32)
- A functional assessment of macrophages from osteopetrotic mice (1979) (31)
- Human fetal osteoclasts fail to express macrophage antigens. (1985) (31)
- Giant cell formation in rabbit long‐term bone marrow cultures: Immunological and functional studies (1986) (31)
- Bone matrix stimulates osteoclastic differentiation in cultures of rabbit bone marrow cells (1989) (30)
- Stimulation of bone formation by dynamic mechanical loading of rat caudal vertebrae is not suppressed by 3-amino-1-hydroxypropylidene-1-bisphosphonate (AHPrBP). (1995) (29)
- Fra‐1 potentiates osteoclastic differentiation in osteoclast‐macrophage precursor cell lines (1999) (28)
- Na+/H(+)-antiporter activity is essential for the induction, but not the maintenance of osteoclastic bone resorption and cytoplasmic spreading. (1992) (28)
- Early effects of hormone replacement therapy on bone. (1999) (28)
- The giant cells recruited by subcutaneous implants of mineralized bone particles and slices in rabbits are not osteoclasts (1991) (28)
- Detection of osteomalacia in British Asians: a comparison of clinical score with biochemical measurements. (1990) (28)
- The birth of the osteoclast (2010) (27)
- Effects of transforming growth factor beta 1 on the regulation of osteoclastic development and function. (1991) (27)
- Osteoclasts are present in the giant cell variant of malignant fibrous histiocytoma (1989) (27)
- The effect of prostaglandins I2, E1, E2 and dibutyryl cyclic AMP on the cytoplasmic spreading of rat osteoclasts. (1984) (27)
- Effect of prostaglandins E1, E2, and F2 alpha on osteoclast formation in mouse bone marrow cultures. (1991) (27)
- Failure of cells of the mononuclear phagocyte series to resorb bone (1984) (27)
- Human osteoclast-specific antigens are expressed by osteoclasts in a wide range of non-human species. (1986) (26)
- Induction of NO and prostaglandin E2 in osteoblasts by wall-shear stress but not mechanical strain. (1997) (26)
- An assessment of the ability of human bone marrow cultures to generate osteoclasts. (1992) (26)
- Fusion of hamster macrophages induced by lectins (1977) (25)
- Distinctive Subdomains in the Resorbing Surface of Osteoclasts (2013) (24)
- Role for parathyroid hormone in mechanical responsiveness of rat bone. (1998) (24)
- Histomorphometric Changes in the Skeleton of Postmenopausal Women With Low Bone Mineral Density Treated With Percutaneous Estradiol Implants (1994) (23)
- Pharmacological control of osteoclastic motility (1983) (23)
- TGF-beta-induced SOCS3 expression augments TNF-alpha-induced osteoclast formation. (2003) (22)
- 3-Amino-1-hydroxypropylidine-1-bisphosphonate (AHPrBP) suppresses not only the induction of new, but also the persistence of existing bone-forming surfaces in rat cancellous bone. (1993) (21)
- Molecular aspects of osteoclast function (2005) (21)
- Parathyroid hormone activates adhesion in bone marrow stromal precursor cells. (2004) (20)
- The mechanism of fusion of hamster macrophages induced by antimacrophage serum (1977) (20)
- The majority of osteoclasts require mRNA and protein synthesis for bone resorption in vitro. (1993) (20)
- TGF-beta 1 and IFN-gamma direct macrophage activation by TNF-alpha to osteoclastic or cytocidal phenotype. (2000) (20)
- Optimal bone resorption by isolated rat osteoclasts requires chloride bicarbonate exchange (1989) (19)
- The effect of oestrogen on megakaryocyte differentiation and platelet counts in vivo. (2006) (19)
- Androgens contribute to the stimulation of cancellous bone formation by ovarian hormones in female rats. (1996) (19)
- A comparison of microanatomic basis for coupling between bone formation and bone resorption in man and the rat. (1993) (18)
- Bone formation is not coupled to bone resorption in a site-specific manner in adult rats. (1992) (18)
- PELVIC ACTINOMYCOSIS AND INTRAUTERINE CONTRACEPTIVE DEVICES (1979) (16)
- The anabolic action of 17 beta-estradiol (E2) on rat trabecular bone is suppressed by (3-amino-1-hydroxypropylidene)-1-bisphosphonate (AHPrBP). (1992) (15)
- Failure of altered macrophage surface to lead to the formation of polykaryons (1977) (15)
- Exploiting the antioxidant potential of a common vitamin: Could vitamin C prevent postmenopausal osteoporosis? (2012) (15)
- Resorption of bone by mouse peritoneal macrophages (1981) (15)
- The role of prostaglandins and nitric oxide in the response of bone to mechanical stimulation. (1997) (15)
- A new approach for calcitonin determination based on target cell responsiveness (1990) (14)
- Stereophotogrammetric observations on bone resorption by isolated rabbit osteoclasts (1984) (14)
- Production and characterisation of immunoreactive calcitonin gene-related peptide (CGRP) from a CGRP receptor-positive cloned osteosarcoma cell line (UMR 106.01). (1989) (14)
- A comparison of the effects of inhibitors of carbonic anhydrase on osteoclastic bone resorption and purified carbonic anhydrase isozyme II (1991) (14)
- Urocortin is a novel regulator of osteoclast differentiation and function through inhibition of a canonical transient receptor potential 1-like cation channel. (2012) (13)
- The rate of cancellous bone formation falls immediately after ovariectomy in the rat. (1994) (13)
- The effect of parathyroid hormone, 1,25-dihydroxycholecalciferol and prostaglandins on the cytoplasmic activity of isolated osteoclasts. (1982) (12)
- An assessment of the prevalence of organic material on bone surfaces (1992) (12)
- On the origin of the osteoclast: The cell surface phenotype of rodent osteoclasts (2007) (12)
- Aminohexane bisphosphonate suppresses bone turnover in postmenopausal women more rapidly than oestrogen-gestagen therapy. (1996) (11)
- The resorptive apparatus of osteoclasts supports lysosomotropism and increases potency of basic versus non-basic inhibitors of cathepsin K. (2010) (11)
- Multiple promoters regulate human calcitonin receptor gene expression. (2000) (11)
- The anabolic effect of 17 beta-oestradiol on the trabecular bone of adult rats is suppressed by indomethacin. (1992) (11)
- A novel assay for analysis of the regulation of the function of human osteoclasts (2006) (11)
- Function of Fos proteins in bone cell differentiation. (1999) (11)
- Bone formation is not coupled to bone resorption in site‐specific manner in adult rats (1993) (11)
- The effect of prostaglandin I2 and 6a-Carba-PGI2 on the motility of isolated osteoclasts. (1983) (10)
- The Direct and Indirect Effects of Estrogen on Bone Formation (1998) (10)
- P16. Differential regulation of osteoclast formation; interleukin 10 (cytokine synthesis inhibitory factor) suppresses formation of osteoclasts but not macrophages in murine bone marrow cultures (1996) (9)
- The progesterone antagonist, RU486 does not affect basal or estrogen-stimulated cancellous bone formation in the rat. (1992) (9)
- Effect of administration and subsequent cessation of buserelin on cancellous bone of female rats (1994) (9)
- Are cathepsin k inhibitors just another class of anti-resorptives? (2013) (8)
- Hormone replacement for osteoporosis (1990) (8)
- Prolonged intermittent but not continuous administration of oestradiol-17 beta increases bone volume in the rat. (1993) (7)
- Distinct effects of ovarian transplantation and exogenous 17 beta-oestradiol on cancellous bone of osteopenic ovariectomized rats. (1995) (7)
- O10. Nitric oxide is an early mediator of the induction of bone formation by mechanical stimulation (1996) (6)
- The effects of ovarian transplantation on bone loss in ovariectomized rats. (1994) (5)
- Reduction in dynamic indices of cancellous bone formation in rat tail vertebrae after caudal neurectomy (1996) (5)
- Symptoms of oestrogen deficiency in women with oestradiol implants (1989) (5)
- The Effects of Pig Interleukin-1 (catabolin) on Bone Resorption by Osteoclasts Disaggregated From Rat Bone (1985) (4)
- P62. Low spinal bone mass in Asian women reflects their small skeleton size (1994) (4)
- FLT 3 ligand can substitute for macrophage colony-stimulating factor in support of osteoclast differentiation and function (2001) (4)
- Vitamin D and the Lymphomedullary System (1984) (4)
- Identification of human osteoclasts with monoclonal antibodies. (1985) (3)
- DMPA and bone density (1991) (3)
- 7. Oestrogen maintains trabecular bone volume in rats not only by suppression of bone resorption but also by stimulation of bone formation (1992) (3)
- Estrogen induces bone formation on non-resorptive surfaces in the rat. (1993) (3)
- Cyclical etidronate prevents spinal bone loss in early post-menopausal women. (1997) (3)
- Inhibition of CTX-II release by cathepsin K inhibition in vivo but not in vitro suggests that anti-resorptive therapy protects cartilage (2015) (2)
- Intermittent retinoic acid in combination with continuous oestradiol-17 beta increases cancellous bone volume in osteopaenic ovariectomized rats. (1994) (2)
- Purification and characterisation of cysteine proteinases from human osteoclastomas. (1991) (2)
- 6. Macrophage colony stimulating factor (M-CSF) is essential for osteoclast formation in vitro (1992) (2)
- Osteoblastic cells induce chemotaxis in osteoclasts (1986) (2)
- Bones need SOFAs (1992) (2)
- 9. High concentrations of 17B-Estradiol stimulate bone formation in adult female rats (1991) (2)
- When is it an osteoclast? (1985) (2)
- Tartrate-resistant acid phosphatase: purification and characterization of the human osteoclastoma enzyme (1988) (1)
- Beta calcitonin gene-related peptide lowers plasma calcium and inhibits osteoclastic bone resorption (1986) (1)
- Mechanical stimulation of rat tail vertebrae induces indomethacin-sensitive expression of insulin-like growth factor-1 mRNA in osteocytes (1995) (1)
- A functional and antigenic assessment of the relationship between osteoclasts and cells of the mononuclear phagocyte series (1985) (1)
- A10 Could ACE-inhibition protect against bone loss? Results from an in vitro study suggesting the existence of a local renin angiotensin system in the bone (1997) (1)
- 114 OSTEOARTHRITIS-LIKE CHANGES IN THE MURINE KNEE JOINT BY MEANS OF FORCED RUNNING (2011) (1)
- Abstract Bone and Tooth Society Annual General Meeting London on Friday 11th October, 1985Surface marker and functional characterization of multinucleate giant cells generated in long term culture of neonatal rabbit bone marrow (1986) (1)
- The Anabolic Action of Estrogen on Rat Bone (1994) (1)
- Effect of the selective cathepsin K inhibitor MIV-711 on bone resorption and cartilage degradation biomarkers and on knee joint pathology in dogs subjected to partial medial meniscectomy, an experimental model of osteoarthritis (2012) (1)
- The effects of human calcitonin on the cytoplasmic spreading of rat osteoclasts (1986) (1)
- Transient reduction in trabecular bone formation after discontinuation of administration of oestradiol-17 beta to ovariectomized rats. (1993) (1)
- Joint meeting of the bone and tooth society and the British endocrine societies 5th and 6th April, 1983, University of YorkThe effect of calcitonin and parathyroid hormone on the cytoplasmic spreading of osteoclasts (1983) (1)
- Regulation of calcitonin release from the 6.23 rat C-cell line by cyclic nucleotide analogues and pharmacological mediators (1991) (1)
- Pharmacological characterization of the potent, selective and orally active cathepsin K inhibitor MIV-711 (2012) (1)
- Cathepsin K inhibitors for the treatment of bone metastasis (2011) (1)
- Prostaglandins and bone resorption: Harvey W, Bennett A 1988: Boca Raton: CRC Press, Inc. £71.50. 134pp (1988) (1)
- Pharmacological and Cellular Interactions in Bone Resorption (1983) (1)
- Structureactivity relationship of human calcitonin-gene-related peptide (2005) (1)
- Hormonal and functional studies on isolated human osteoclasts (1984) (1)
- P12. Mechanism of inhibition of bone resorption by bisphosphonates (1990) (1)
- Calcitonin and alendronate activate Ca2+-permeable cation conductances with distinct transient receptor potential properties in murine osteoclasts (2010) (1)
- The Multinucleate Cells in of the Jaw Are (1988) (1)
- Generation of cell lines with potent ability to induce osteoclastic differentiation and stimulate osteoclastic function (1992) (1)
- This information is current as Lineage Commitment In Vitro Expression in Osteoclast/Macrophage Suppressors of Cytokine Signaling -Induced β The Possible Role of TGF- (2013) (0)
- P24. The effect of triiodothyronine (T3) on osteoclast bone resorption in-vitro (1992) (0)
- Production and characterization of new monoclonal antibodies to human osteoclasts (1991) (0)
- P30. Osteoclasts derive from haemopoietic cells (1989) (0)
- Erratum to 'Cathepsin K inhibitors prevent matrix-derived growth factor degradation by human osteoclasts'. (2021) (0)
- P7. Purification of tartrate-resistant acid phosphatase from osteoclastomas (1988) (0)
- P15. Aminohexane diphosphonate suppresses bone turnover in postmenopausal women more rapidly than oestrogen-gestagen therapy (1996) (0)
- The control of osteoclastic motility (1984) (0)
- P4. Plasma immunoreactive parathyroid hormone (PTH) concentration in the detection of osteomalacia (OM) in asian out-patients (1988) (0)
- Osteoblasts initiate bone resorption by exposing bone mineral to osteoclastic contact (1986) (0)
- LABELING OF MONONUCLEAR PHAGOCYTES IN GRANULOMAS AND INFLAMMATORY SITES (1981) (0)
- Parathyroid hormone augments the osteocytic response to mechanical stimulation, and potentiate mechanically-induced bone formation (1996) (0)
- Ovarian transplantation maintains bone formation more effectively than exogenous oestrogen in ovariectomised osteopenic rats (1995) (0)
- O11. Bone formation induced by mechanical stimulation in rat caudal vertebrae is not dependent on bone resorption (1994) (0)
- The use of bisphosphonate (pamidronate) treatment to modulate fracture repair (1993) (0)
- P33. Tri-iodothyronine does not affect osteoclast formation in mouse bone marrow culture (1994) (0)
- Parathyroid hormone (PTH) is an indirect stimulator of osteoclastic bone resorption (1985) (0)
- Scanning Microscopy of Vertebrate Mineralized Tissues. A Compilation in Memory of Edward J. Reith. Lawrence Martin , Alan Boyde , Frederick Grine , Sheila Jones (1990) (0)
- Tumor Necrosis Factor- (cid:1) Mediates Osteopenia Caused by Depletion of Antioxidants (2004) (0)
- 112 EFFECT OF THE SELECTIVE CATHEPSIN K INHIBITOR, MIV-711, ON MARKERS OF CARTILAGE DEGRADATION AND ON GROSS AND HISTOPATHOLOGY SCORES IN DOGS SUBJECTED TO PARTIAL MEDIAL MENISCECTOMY, AN EXPERIMENTAL MODEL OF OSTEOARTHRITIS (2011) (0)
- Modulation of osteoclastic behaviour by chemokines (1995) (0)
- Analysis, isolation and in vitro culture of osteoclasts and their presumed precursors by osteoclast-specific monoclonal antibodies and fluorescent-activated cell sorting (1986) (0)
- P16. Ovarian transplantation in the rat prevents ovariectomyinduced bone loss (1994) (0)
- Role of collagenase in bone resorption: lack of action in resorptive hernivacuole but high expression in sub-population of cells co-distributed with osteoclasts (1995) (0)
- P7. Effect of stopping buserelin treatment on cancellous bone of female rats (1994) (0)
- P10. Heparin and related glycosaminoglycans stimulate bone resorption by isolated osteoclasts incubated in the presence of serum (1990) (0)
- P23. Effects of 5α-dihydrotesterone on the skeleton of ovariectomised rats (1994) (0)
- VITAMIN D AND THE LYMPHOMEDULLARY SYSTEM (1984) (0)
- P11. Osteoblast-medicated effect of TGFβ on osteoclastic bone resorption (1990) (0)
- PLASMA 25-OHVITAMIN D AND PTH IN THE DETECTION OF OSTEOMALACIA IN ASIAN OUTPATIENTS (1988) (0)
- Characterization of an acid collagenase from human osteoclastomas (1988) (0)
- P13. Androgens are involved in the regulation of cancellous bone formation in female rats (1996) (0)
- Hormone-responsive release of acid phosphatase by isolated osteoclasts (1987) (0)
- Abstract from the Bone and Tooth Society Summer Meeting, July 22–23, 1993 Marrow Stromal Cell Differentiation: A Conference in Honour of Dr. Maureen Owen PosterP77. Intermittent retinoic acid increases bone volume in 17β-oestradiol-treated osteopenic rats (1994) (0)
- Cytocidal Phenotype to Osteoclastic or α Activation by TNF-Direct Macrophage γ and IFN-1 β TGF-Lean and (2000) (0)
- P19. The effect of hepatocyte growth factor on the behaviour of isolated rat osteoclasts (1996) (0)
- The effect of calcium-regulating hormones and prostaglandins on bone resorption by disaggregated human and rabbit osteoclasts (1986) (0)
- [Role of calcitonin in bone]. (1985) (0)
- IL-18(IFN-γ誘導因子)は破骨細胞前駆細胞に直接作用し、GM-CSF産生を介して破骨細胞の分化を抑制する (1997) (0)
- Expression of a store-operated conductance and mRNA for canonical transient receptor potential and Orai in murine osteoclasts (2010) (0)
- Boyd's introduction to the study of disease (1989) (0)
- P13. Prostaglandins simultaneously stimulate the formation and inhibit the function of osteoclasts (1990) (0)
- Poster Presentation: P-23. The Histomorphometrical Changes in Bone of Post-menopausal Women with Low Bone Mineral Density Treated with Percutaneous Oestradiol Implants (1994) (0)
- Interleukin 1 (IL1) induces osteoblastic cells to stimulate osteoclastic bone resorption (1985) (0)
- Urocortin prevents bone resorption by inhibiting a constitutively active transient receptor potential-like cation channel (2010) (0)
- TΗΕ ROLE OF 1,25-DIHYDROXYVITAMIN D3 IN ΊΗΕ GENERATION AND REGULATION OF OSTEOCLASTS. (1988) (0)
- Trapidil abolishes the increase in bone formation induced by ovariectomy in rats (2010) (0)
- 8. Consistent presence of unmineralised organic material covering bone surfaces (1991) (0)
- Hormonal induction of osteoclastic phenotype from haemopoietic precursors in vitro (1987) (0)
- P76. The novel oestrogen antagonist ICI 182,780 abolishes oestrogen's anabolic effect on the rat skeleton (1994) (0)
- A study of in vitro resorption of bone by human osteoclasts using microradiography in conjunction with scanning electron microscopy (1985) (0)
- P75. M-CSF suppresses osteoclastic apoptosis and switches function from bone resorption to migration/chemotaxis (1994) (0)
- Osteoclast differentiation and function (2007) (0)
- Visualisation of the apical surface of activated osteoclasts (2012) (0)
- O14. Bone loss observed in inflammatory bowel disease is associated with suppression of bone formation (1996) (0)
- 3. Evidence that an osteoclastic resorption-stimulatory activity is associated with the osteoblast cell surface and/or the extracellular matrix (1990) (0)
- All-trans retinoic acid reversibly suppresses cancellous bone formation in intact female rats (1995) (0)
- Structural modifications of human CGRP and their effect on osteoclastic bone resorption (1987) (0)
- P17. Analysis of gene expression after mechanical stimulation of bone: C-fos expression is induced in osteocytes within 60 minutes of mechanical stimulation (1996) (0)
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What Schools Are Affiliated With Timothy John Chambers?
Timothy John Chambers is affiliated with the following schools:
