Timothy J. Rink
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Timothy J. Rinkbiology Degrees
Biology
#11421
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#14814
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Molecular Biology
#1754
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#1783
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Biochemistry
#1884
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#2025
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Chemistry Biology
Timothy J. Rink's Degrees
- PhD Biochemistry University of California, Berkeley
- Masters Molecular Biology Stanford University
Why Is Timothy J. Rink Influential?
(Suggest an Edit or Addition)Timothy J. Rink's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Calcium homeostasis in intact lymphocytes: cytoplasmic free calcium monitored with a new, intracellularly trapped fluorescent indicator (1982) (2011)
- Cytoplasmic pH and free Mg2+ in lymphocytes (1982) (991)
- T-cell mitogens cause early changes in cytoplasmic free Ca2+ and membrane potential in lymphocytes (1982) (943)
- SK&F 96365, a novel inhibitor of receptor-mediated calcium entry. (1990) (780)
- Single stretch-activated ion channels in vascular endothelial cells as mechanotransducers? (1987) (730)
- Measurement of cytosolic free Ca2+ in individual small cells using fluorescence microscopy with dual excitation wavelengths. (1985) (599)
- Diacylglycerol and phorbol ester stimulate secretion without raising cytoplasmic free calcium in human platelets (1983) (505)
- Cytoplasmic free Ca2+ in human platelets: Ca2+ thresholds and Ca‐independent activation for shape‐change and secretion (1982) (494)
- Fluorescence and bioluminescence measurement of cytoplasmic free calcium. (1987) (490)
- Neutral carrier ion-selective microelectrodes for measurement of intracellular free calcium. (1980) (443)
- Calcium oscillations (1989) (373)
- Repetitive spikes in cytoplasmic calcium evoked by histamine in human endothelial cells (1988) (373)
- Lymphocyte membrane potential assessed with fluorescent probes. (1980) (315)
- Free calcium in heart muscle at rest and during contraction measured with Ca2+-sensitive microelectrodes (1980) (263)
- Liberation of [3H]arachidonic acid and changes in cytosolic free calcium in fura-2-loaded human platelets stimulated by ionomycin and collagen. (1986) (249)
- Agonists stimulate divalent cation channels in the plasma membrane of human platelets (1985) (239)
- Receptor-mediated calcium entry in fura-2-loaded human platelets stimulated with ADP and thrombin. Dual-wavelengths studies with Mn2+. (1989) (205)
- Regulation of cytosolic free calcium in fura-2-loaded rat parotid acinar cells. (1987) (203)
- High affinity amylin binding sites in rat brain. (1993) (200)
- What turns platelets on (1984) (189)
- Stimulus-response coupling in human platelets. Changes evoked by platelet-activating factor in cytoplasmic free calcium monitored with the fluorescent calcium indicator quin2. (1984) (186)
- Anti-immunoglobulin, cytoplasmic free calcium, and capping in B lymphocytes (1982) (185)
- Dose-response for glucagonostatic effect of amylin in rats. (1997) (178)
- Dose-responses for the slowing of gastric emptying in a rodent model by glucagon-like peptide (7-36) NH2, amylin, cholecystokinin, and other possible regulators of nutrient uptake. (1996) (152)
- Free calcium ions in neurones of Helix aspersa measured with ion‐selective micro‐electrodes. (1981) (142)
- Thrombin and ionomycin can raise platelet cytosolic Ca2+ to micromolar levels by discharge of internal Ca2+ stores: studies using fura-2. (1986) (139)
- Gastric emptying is accelerated in diabetic BB rats and is slowed by subcutaneous injections of amylin (1995) (138)
- Free calcium in Xenopus embryos measured with ion-selective microelectrodes (1980) (130)
- Responses to adenosine diphosphate in human platelets loaded with the fluorescent calcium indicator quin2. (1985) (130)
- Receptor‐mediated calcium entry (1990) (120)
- Preclinical pharmacology of pramlintide in the rat: Comparisons with human and rat amylin (1996) (117)
- Ca2+-selective electrodes: A novel PVC-gelled neutral carrier mixture compared with other currently available sensors (1981) (108)
- Molecular physiology of amylin (1994) (104)
- Structure and biology of amylin. (1993) (103)
- Platelet activating factor raises intracellular calcium ion concentration in macrophages (1986) (98)
- Receptor-mediated Ca2+ entry: diversity of function and mechanism. (1989) (93)
- Rapid increases in cytosolic free calcium in response to muscarinic stimulation of rat parotid acinar cells. (1987) (92)
- Calcium oscillations in non-excitable cells (1989) (90)
- The effects of substance P and carbachol on inositol tris- and tetrakisphosphate formation and cytosolic free calcium in rat parotid acinar cells. A correlation between inositol phosphate levels and calcium entry. (1987) (87)
- Calcium signalling in non-excitable cells: notes on oscillations and store refilling. (1989) (73)
- Dose response characteristics for the hyperglycemic, hyperlactemic, hypotensive and hypocalcemic actions of amylin and calcitonin gene-related peptide-I (CGRP alpha) in the fasted, anaesthetized rat. (1993) (64)
- In search of a satiety factor (1994) (61)
- TMB‐8 inhibits secretion evoked by phorbol ester at basal cytoplasmic free calcium in quin2‐loaded platelets much more effectively than it inhibits thrombin‐induced calcium mobilisation (1984) (57)
- The role of cytoplasmic free calcium in the responses of quin2-loaded human platelets to vasopressin. (1984) (56)
- Response to intravenous injections of amylin and glucagon in fasted, fed, and hypoglycemic rats. (1993) (55)
- Relationship between cytoplasmic free calcium and myosin light chain phosphorylation in intact platelets. (1985) (55)
- Effects of SK&F 94120, an inhibitor of cyclic nucleotide phosphodiesterase type III, on human platelets. (1988) (54)
- Selective amylin antagonist suppresses rise in plasma lactate after intravenous glucose in the rat (1994) (47)
- Amylin regulation of carbohydrate metabolism. (1995) (47)
- Trifluoperazine and chlorpromazine block secretion from human platelets evoked at basal cytoplasmic free calcium by activators of C‐kinase (1983) (46)
- 8–37h‐CGRP antagonizes actions of amylin on carbohydrate metabolism in vitro and in vivo (1991) (44)
- Effects of prostaglandin I2 and forskolin on the secretion from platelets evoked at basal concentrations of cytoplasmic free calcium by thrombin, collagen, phorbol ester and exogenous diacylglycerol. (1984) (43)
- Low concentrations of the stable prostaglandin endoperoxide U44069 stimulate shape change in quin2‐loaded platelets without a measurable increase in [Ca2+]i (1986) (43)
- SPECIAL REPORT Regulation of muscle glycogen metabolism by CGRP and amylin: CGRP receptors not involved (1995) (42)
- Octimibate, a potent non‐prostanoid inhibitor of platelet aggregation, acts via the prostacyclin receptor (1991) (40)
- Diabetogenic effects of salmon calcitonin are attributable to amylin-like activity. (1995) (40)
- Amylin and insulin in rat soleus muscle: dose responses for cosecreted noncompetitive antagonists. (1992) (38)
- The effects of siguazodan, a selective phosphodiesterase inhibitor, on human platelet function (1990) (34)
- A real receptor-operated calcium channel? (1988) (34)
- 8–37hCGRP, an amylin receptor antagonist, enhances the insulin response and perturbs the glucose response to infused arginine in anesthetized rats (1992) (33)
- Differential antagonism of amylin's metabolic and vascular actions with amylin receptor antagonists. (1995) (30)
- Stimulus-secretion coupling: a perspective highlighting the contributions of Peter Baker. (1988) (24)
- Cytosolic calcium in platelet activation (1988) (23)
- Amylin and Syndrome‐X (1994) (23)
- Dose-dependent elevation of cyclic AMP, activation of glycogen phosphorylase, and release of lactate by amylin in rat skeletal muscle. (1995) (20)
- Amylin and epinephrine have no direct effect on glucose transport in isolated rat soleus muscle (1995) (18)
- Measurement of free calcium concentration in living cells (1983) (18)
- Primate vascular responses to octimibate, a non‐prostanoid agonist at the prostacyclin receptor (1991) (18)
- Amylin is more potent and more effective than glucagon in raising plasma glucose concentration in fasted, anesthetized rats. (1991) (18)
- Lactate production from the rat hindlimb is increased after glucose administration and is suppressed by a selective amylin antagonist: evidence for action of endogenous amylin in skeletal muscle. (1995) (17)
- Comparison of the in vitro and in vivo pharmacology of adrenomedullin, calcitonin gene-related peptide and amylin in rats. (1996) (14)
- Evidence for release of free glucose from muscle during amylin‐induced glycogenolysis in rats (1993) (12)
- Induction of acute hyperglycemia, hyperlactemia and hypocalcemia in fed and fasted BALB/c mice by intravenous amylin injection. (1992) (11)
- Control and interrelation of aggregation and secretion; the roles of Ca2+, diacylglycerol and thromboxane with particular reference to ADP stimulation. (1985) (11)
- Free Ca2+ requirements of agonist-induced thromboxane A2 synthesis in human platelets. (1986) (11)
- Cytoplasmic free [Ca2+] in very small intact cells. (1982) (11)
- Insights into platelet function gained with fluorescent Ca2+ indicators (1987) (10)
- 13 – Receptor-mediated Calcium Entry (1989) (10)
- Intracellular pH and cytoplasmic free Ca2+ (1987) (10)
- Calcium and Diacylglycerol (1985) (6)
- Measurement of cytosolic calcium: fluorescent calcium indicators. (1988) (5)
- Calcium activities and fluxes inside small intact cells as measured with intracellularly trapped chelators. (1984) (5)
- Measurement of Free Ca2+ in Nerve Cell Bodies (1981) (5)
- Hypertension and inhibition of the sodium pump: a strong link but in which chain? (1982) (5)
- Calcium signalling. (1990) (4)
- Design and synthesis of a series of glycerol-derived receptor mediated calcium entry (RMCE) blockers (1990) (3)
- Effects of thromboxane and prostaglandins on cytoplasmic free Ca directly measured in human platelets with the fluorescent indicator quin2 (1984) (3)
- Roger Yonchien Tsien (1952–2016) (2016) (3)
- Changes in free Ca during muscle contraction, measured with an intracellular Ca-selective electrode [proceedings]. (1978) (2)
- Genetics. In search of a satiety factor. (1994) (2)
- Repetitive spiking of cytoplasmic calcium in human endothelial cells (1989) (1)
- Amylin action: physiologic basis and pathologic correlations (1991) (1)
- Anti-lmmunoglobulin, Cytoplasmic and Capping in B Lymphocytes Free Calcium, (2002) (0)
- Open Question What turns platelets on (1984) (0)
- Dosage de l'activite de l'amyline (1992) (0)
- Methods for reducing gastrointestinal motility (1994) (0)
- Methodes pour la regulation de la motilite gastro-intestinale (1994) (0)
- Amylin or amylinanaloga containing composition which also contains optionally insulin, for the treatment of anorexia and related conditions (1992) (0)
- Testing the activity of amylin. (1992) (0)
- antagonists on receptor basic operating procedures for screening amylin agonists and (1992) (0)
- Insights into the role of PAF new horizons in platelet activating factor research: edited by C.M. Winslow and M.L. Lee, John Wiley & Sons, 1987. £34.50/$64.55 (xiv + 373 pages) ISBN 0 471 91237 9 (1987) (0)
- Aktivätsmessungen of amylin (1992) (0)
- PAF-induced changes in [ Ca 2 + ] i in human platelets (2005) (0)
- Agonist Stimulated Changes in Human Endothelial Cell Cytosolic Calcium (1989) (0)
- Obituary: Roger Yonchien Tsien MD, PhD: 1952 – 2016 (2017) (0)
- Amylin or amylinanalogpræparat optionally containing insulin, for the treatment of anorexia and related conditions (1992) (0)
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