Thomas L. Perry
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Thomas L. Perryphilosophy Degrees
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Thomas L. Perrybiology Degrees
Biology
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Philosophy Biology
Thomas L. Perry's Degrees
- PhD Neuroscience Stanford University
- Doctorate Medicine Stanford University
Why Is Thomas L. Perry Influential?
(Suggest an Edit or Addition)Thomas L. Perry's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Parkinson's disease: A disorder due to nigral glutathione deficiency? (1982) (768)
- Huntington's Chorea (1973) (699)
- Idiopathic Parkinson's disease, progressive supranuclear palsy and glutathione metabolism in the substantia nigra of patients (1986) (383)
- REGIONAL DISTRIBUTION OF AMINO ACIDS IN HUMAN BRAIN OBTAINED AT AUTOPSY (1971) (296)
- Technical pitfalls leading to errors in the quantitation of plasma amino acids. (1969) (265)
- Postmortem Changes of Amino Compounds in Human and Rat Brain (1981) (244)
- CSF amino acids and plasma‐CSF amino acid ratios in adults 1 (1975) (211)
- A versatile lithium buffer elution system for single column automatic amino acid chromatography. (1968) (204)
- FREE AMINO ACIDS AND RELATED COMPOUNDS IN BIOPSIES OF HUMAN BRAIN (1971) (192)
- Dominantly inherited olivopontocerebellar atrophy from eastern Cuba Clinical, neuropathological, and biochemical findings (1989) (191)
- Partial protection from the dopaminergic neurotoxin N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine by four different antioxidants in the mouse (1985) (182)
- Amyotrophic lateral sclerosis: Amino acid levels in plasma and cerebrospinal fluid (1990) (169)
- Hallervorden‐Spatz disease: Cysteine accumulation and cysteine dioxygenase deficiency in the globus pallidus (1985) (161)
- Huntington's chorea. Deficiency of gamma-aminobutyric acid in brain. (1973) (147)
- Nigrostriatal Dopaminergic Neurons Remain Undamaged in Rats Given High Doses of l‐DOPA and Carbidopa Chronically (1984) (142)
- Hereditary mental depression and Parkinsonism with taurine deficiency. (1975) (132)
- Depletion of glutathione in brainstem of mice caused by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine is prevented by antioxidant pretreatment (1986) (124)
- Brain glutamate deficiency in amyotrophic lateral sclerosis (1987) (123)
- Amino acids, glutathione, and glutathione transferase activity in the brains of patients with Alzheimer's disease (1987) (121)
- Amino acid abnormalities in epileptogenic foci (1981) (120)
- Normal cerebrospinal fluid and brain glutamate levels in schizophrenia do not support the hypothesis of glutamatergic neuronal dysfunction (1982) (120)
- Nonketotic hyperglycinemia. Glycine accumulation due to absence of glycerine cleavage in brain. (1975) (117)
- Carnosinemia. A new metabolic disorder associated with neurologic disease and mental defect. (1967) (108)
- SUSTAINED DRUG‐INDUCED ELEVATION OF BRAIN GABA IN THE RAT 1 (1973) (107)
- GABA CONTENT AND GLUTAMIC ACID DECARBOXYLASE ACTIVITY IN BRAIN OF HUNTINGTON'S CHOREA PATIENTS AND CONTROL SUBJECTS 1 (1975) (98)
- γ‐VINYL GABA: EFFECTS OF CHRONIC ADMINISTRATION ON THE METABOLISM OF GABA AND OTHER AMINO COMPOUNDS IN RAT BRAIN (1979) (98)
- Reporting of 6-month vs 12-month data in a clinical trial of celecoxib. (2001) (97)
- THE OCCURRENCE OF AMINES IN HUMAN URINE: DETERMINATION BY COMBINED ION EXCHANGE AND PAPER CHROMATOGRAPHY. (1963) (88)
- Homocystinuria: A recently discovered cause of mental defect and cerebrovascular thrombosis (1966) (83)
- Dominantly inherited apathy, central hypoventilation, and Parkinson's syndrome (1990) (83)
- HYPERMETHIONINEMIA: A METABOLIC DISORDER ASSOCIATED WITH CIRRHOSIS, ISLET CELL HYPERPLASIA, AND RENAL TUBULAR DEGENERATION. (1965) (81)
- Familial fatal parkinsonism with alveolar hypoventilation and mental depression (1979) (80)
- β-N-Methylamino-l-alanine Chronic oral administration is not neurotoxic to mice (1989) (79)
- What excitotoxin kills striatal neurons in Huntington's disease? Clues from neurochemical studies (1990) (78)
- Lactic acidosis in three sibs due to defects in both pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase complexes. (1976) (77)
- The amino acid content of human cerebrospinal fluid in normal individuals and in mental defectives. (1961) (74)
- REGIONAL DISTRIBUTION OF HOMOCARNOSINE, HOMOCARNOSINE‐CARNOSINE SYNTHETASE AND HOMOCARNOSINASE IN HUMAN BRAIN (1979) (73)
- Cerebral Amino Acid Pools (1982) (72)
- AMINES OF HUMAN WHOLE BRAIN * (1967) (72)
- BIOCHEMICAL EFFECTS IN MAN and RAT OF THREE DRUGS WHICH CAN INCREASE BRAIN GABA CONTENT (1978) (69)
- Neurotransmitter amino acids in dominantly inherited cerebellar disorders (1981) (69)
- URINARY EXCRETION OF AMINES IN NORMAL CHILDREN (1962) (68)
- Sulfur-containing amino acids in the plasma and urine of homocystinurics. (1967) (67)
- Failure to detect 3,4-Dimethoxyphenylethylamine in the Urine of Schizophrenics (1964) (66)
- Treatment of homocystinuria with a low-methionine diet, supplemental cystine, and a methyl donor. (1968) (65)
- Volatile fatty acids in normal human physiological fluids. (1970) (65)
- Amino acids in human epileptogenic foci. (1975) (64)
- Paraquat and two endogenous analogues of the neurotoxic substance N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine do not damage dopaminergic nigrostriatal neurons in the mouse (1986) (64)
- Cerebrospinal fluid values for monoamine metabolites, gamma-aminobutyric acid, and other amino compounds in Rett syndrome. (1988) (64)
- Plasma-aminoacid levels in Huntington's chorea. (1969) (63)
- Glutamine depletion in phenylketonuria. A possible cause of the mental defect. (1970) (63)
- 7-Hydroxychlorpromazine: Potential Toxic Drug Metabolite in Psychiatric Patients (1964) (62)
- Isoniazid therapy of Huntington disease (1979) (60)
- Urinary amines of intestinal bacterial origin. (1966) (59)
- Monoamine oxidase B, smoking, and Parkinson's disease (1986) (58)
- Unrecognized adult phenylketonuria. Implications for obstetrics and psychiatry. (1973) (57)
- Early diagnosis and treatment of homocystinuria. (1966) (56)
- Serum-carnosinase deficiency in carnosinaemia. (1968) (55)
- Human CSF GABA Concentrations: Revised Dowd for Controls, but Not Decreased in Huntington's Chorea (1982) (53)
- HOMOCARNOSINE IN HUMAN CEREBROSPINAL FLUID: AN AGE‐DEPENDENT PHENOMENON 1 (1968) (53)
- Effects of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and its metabolite, N-methyl-4-phenylpyridinium ion, on dopaminergic nigrostriatal neurons in the mouse (1985) (51)
- Striatal GABAergic Neuronal Activity Is Not Reduced in Parkinson's Disease (1983) (51)
- Passage of taurine into adult mammalian brain (1974) (50)
- Aspartate‐taurine imbalance in dominantly inherited olivopontocerebellar atrophy (1977) (49)
- Biochemical Studies of Erythrocytes in a Patient with Pyroglutamic Acidemia (5-Oxoprolinemia) (1976) (47)
- A simple test for heterozygosity for phenylketonuria (1967) (46)
- α-Tocopherol and β-carotene do not protect marmosets against the dopaminergic neurotoxicity of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (1987) (45)
- Urinary screening tests in the prevention of mental deficiency. (1966) (44)
- Partial protective effect of MK-801 on MPTP-induced reduction of striatal dopamine in mice (1992) (43)
- ALIPHATIC AND AROMATIC AMINES OF CAT BRAIN * (1965) (43)
- Chronic parkinsonism secondary to intranasal administration of a product of meperidine-analogue synthesis. (1984) (43)
- Effects of 3-acetylpyridine on putative neurotransmitter amino acids in rat cerebellum (1976) (42)
- Elevation of Brain GABA Content by Chronic Low‐Dosage Administration of Hydrazine, a Metabolite of Isoniazid (1981) (41)
- Determination of heterozygosity for phenylketonuria on the amino acid analyzer. (1967) (41)
- Quantification of free amino compounds of rat brain: identification of hypotaurine 1 (1973) (40)
- Metabolic Studies of a Family with Massive Formiminoglutamic Aciduria (1975) (40)
- Amino compounds and organic acids in CSF, plasma, and urine of autistic children. (1978) (39)
- HOMOCARNOSINOSIS: INCREASED CONTENT OF HOMOCARNOSINE AND DEFICIENCY OF HOMOCARNOSINASE IN BRAIN (1979) (39)
- 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) does not destroy nigrostriatal neurons in the scorbutic guinea pig. (1985) (38)
- Neurochemical Abnormalities in Brains of Renal Failure Patients Treated by Repeated Hemodialysis (1985) (37)
- Cystathioninuria in Two Healthy Siblings (1968) (37)
- Failure of aminooxyacetic acid therapy in Huntington disease (1980) (36)
- AMINE CONTENT OF NORMAL HUMAN CEREBROSPINAL FLUID * (1964) (35)
- Urinary Excretion of Amines in Phenylketonuria and Mongolism (1962) (34)
- Urinary Amines in Chronic Schizophrenia (1966) (33)
- Brain amino acids and glutathione in progressive supranuclear palsy (1988) (32)
- Concurrence of cystathioninuria, nephrogenic diabetes insipidus and severe anemia. (1967) (32)
- Stereoselective disposition of racemic E‐10‐hydroxynortriptyline in human beings (1989) (32)
- Identity and Significance of Some Pink Spots in Schizophrenia and Other Conditions (1967) (31)
- Studies of the Glycine Cleavage Enzyme System in Brain from Infants with Glycine Encephalopathy (1977) (31)
- A controlled trial of isoniazid therapy for action tremor in multiple sclerosis (2004) (31)
- Neurochemical abnorrnalities in a patient with ataxia‐ telangiectasia (1984) (30)
- Effects of chronic administration of antipsychotic drugs on GABA and other amino acids in the mesolimbic area of rat brain. (1979) (30)
- 4-Phenylpyridine and three other analogues of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine lack dopaminergic nigrostriatal neurotoxicity in mice and marmosets (1987) (29)
- FREE AMINO ACIDS AND RELATED COMPOUNDS IN FIVE REGIONS OF BIOPSIED CAT BRAIN (1972) (29)
- Brain choline acetyltransferase reduction in dominantly inherited olivopontocerebellar atrophy (1987) (28)
- Interconversion of serine and glycine is normal in psychotic patients (1985) (27)
- Tetrahydroisoquinoline lacks dopaminergic nigrostriatal neurotoxicity in mice (1988) (27)
- Exposure to cigarette smoke does not decrease the neurotoxicity of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice (1987) (27)
- Morphometric studies in dominant olivopontocerebellar atrophy. Comparison of cell losses with amino acid decreases. (1990) (27)
- EXOGENOUS URINARY AMINES OF PLANT ORIGIN. (1965) (26)
- SUBSTRATE SPECIFICITY OF DOPA DECARBOXYLASE. (1964) (26)
- Manipulation of glutathione contents fails to alter dopaminergic nigrostriatal neurotoxicity of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the mouse (1986) (25)
- Excitatory Amino Acid Receptor Antagonist in Murine Motoneuron Disease (The Wobbler Mouse) (1992) (25)
- Identification of the diketopiperazine of histidylproline in human urine. (1965) (25)
- Schizophrenia, tardive dyskinesia, and brain GABA (1989) (24)
- Hyperprolinaemia in two successive ǵenerations of a North American Indian family (1968) (24)
- Amyotrophic Lateral Sclerosis: Interleukin-6 Levels in Cerebrospinal Fluid (1992) (24)
- γ‐Aminobutyric acid: drug‐induced elevation in monkey brain 1 (1974) (23)
- Lactic acidosis due to pyruvate carboxylase deficiency (1981) (23)
- Brain amino acids in baboons with light-induced epilepsy. (1973) (22)
- ISOLATION AND IDENTIFICATION OF γ‐AMINOBUTYRYL‐CYSTATHIONINE FROM HUMAN BRAIN AND CSF (1977) (22)
- Benzodiazepine Receptor Binding in Cerebellar Cortex: Observations in Olivopontocerebellar Atrophy (1984) (22)
- Is GABA detectable in human CSF? (1976) (21)
- Homolanthionine Excretion in Homocystinuria (1966) (21)
- N-Methylmetanephrine: Excretion by Juvenile Psychotics (1963) (20)
- Increased GABA receptor binding in dominantly-inherited cerebellar ataxias (1983) (20)
- Brain amino acid contents are dissimilar in sporadic and Guamanian amyotrophic lateral sclerosis (1990) (18)
- Chronic organic manganese administration in the rat does not damage dopaminergic nigrostriatal neurons. (1986) (18)
- The wobbler mouse: amino acid contents in brain and spinal cord (1991) (18)
- Phenylketonuria in a woman of normal intelligence and her child. (1966) (18)
- Biochemical investigations of biopsied brain tissue and autopsied organs from a patient with pyroglutamic acidemia (5-oxoprolinemia). (1981) (17)
- Homocystinuria: Excretion of a New Sulfur-Containing Amino Acid in Urine (1966) (17)
- Urinary bacteria: potential source of some organic acidurias. (1972) (17)
- Amyotrophic lateral sclerosis (1991) (17)
- Glucuronidation of the enantiomers of E-10-hydroxynortriptyline in human and rat liver microsomes. (1987) (17)
- Defective 5-Hydroxylation of Tryptophan in Phenylketonuria.∗ (1964) (16)
- Amino acid and enzyme studies of brain and other tissues in an infant with argininosuccinic aciduria. (1980) (16)
- The incidence of mental illness in the relatives of individuals suffering from phenylketonuria or mongolism (1966) (16)
- Brain γ‐aminobutyric acid deficiency in dialysis encephalopathy (1985) (15)
- Cerebrospinal fluid and plasma glutamine elevation by anticonvulsant drugs: a potential diagnostic and therapeutic trap. (1976) (15)
- Alpha-tocopherol and beta-carotene do not protect marmosets against the dopaminergic neurotoxicity of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. (1987) (15)
- Some ethical problems in Huntington's chorea. (1981) (15)
- Severe atovaquone-resistant Plasmodium falciparum malaria in a Canadian traveller returned from the Indian subcontinent (2009) (15)
- ε-N-Methyl Lysine: an Additional Amino-acid in Human Plasma (1969) (15)
- Acetic and benzoic acids in the urine of patients with chronic schizophrenia. (1971) (14)
- Unimpaired Learning Ability of Rats Made Artificially Phenylketonuric During Fetal or Neonatal Life.∗ (1965) (14)
- Iatrogenic Urinary Amino-Acid Derived from Penicillin (1965) (14)
- Concentrations of GABA and Other Amino Acids in CSF from Torsion Dystonia Patients (1982) (14)
- Methionine induction of experimental tyrosinaemia. (2008) (13)
- Sucrosuria and mental deficiency: a coincidence. (1959) (13)
- Brain amino acid abnormalities in pyruvate carboxylase deficiency (1985) (13)
- 2-Phenylpyridine and 3-phenylpyridine, constituents of tea, are unlikely to cause idiopathic Parkinson's disease (1988) (12)
- Brain neurotransmitters in glycine encephalopathy (1988) (12)
- Information for Physicians and Pharmacists About Drugs That Might Cause Dry Mouth: A Study of Monographs and Published Literature (2013) (12)
- N-Acetylcystathionine: a New Urinary Amino-acid in Congenital Cystathioninuria (1968) (12)
- Plasma amino acid levels in children of patients with Huntington's chorea (1972) (12)
- Urinary excretion of trace metals in Huntington's chorea (1961) (11)
- Abnormalities in neurotransmitter amino acids in dominantly inherited cerebellar disorders. (1978) (11)
- Treatment of Huntington's chorea with isoniazid. (1977) (11)
- Hyperasparaginemia in a schizophrenic patient. (1983) (10)
- Etiologic factors in mental deficiency; errors of metabolism that may lead to mental deficiency. (1958) (10)
- Occurrence of putreanine in human brain 1 (1972) (10)
- Excessive hypertension and pulmonary edema after electroconvulsive therapy. (2005) (10)
- Amino acid analysis of speech areas in human brain; absence of left-right asymmetry. (1972) (9)
- Brain amino compounds in a Huntington's disease pratient on isoniazid therapy (1985) (9)
- Urinary cyclic AMP in periodic catatonia. (1973) (8)
- Cystinylglycine in plasma: diagnostic relevance for pyroglutamic acidemia, homocystinuria, and phenylketonuria. (1981) (8)
- Mitochondrial encephalomyopathy with associated aminoacidopathy in a male sibship. (1989) (7)
- Studies of amino acid content and transport in glutathione-deficient erythrocytes from a patient with pyroglutamic acidemia (5-oxoprolinemia). (1981) (7)
- G.A.B.A. IN HUNTINGTON'S CHOREA (1974) (7)
- Gamma-aminobutyric acid: drug-induced elevation in monkey brain. (1974) (7)
- Four biochemically different types of dominantly inherited olivopontocerebellar atrophy. (1984) (7)
- Neuronal [3H]Benzodiazepine Binding and Levels of GABA, Glutamate, and Taurine Are Normal in Huntington's Disease Cerebellum (1983) (7)
- Failure to detect trans-3-methyl-2-hexenoic acid in the sweat of schizophrenic patients. (1970) (6)
- Chronic treatment with ACTH1-24 does not produce permanent damage to the developing rat brain. (1985) (6)
- Comparison of the oscillometric blood pressure monitor ( ) BPM-100 with the auscultatory mercury sphygmomanometerBeta (2001) (6)
- Elevation of γ-aminobutyric acid in human brain may increase dopaminergic neuronal function (1984) (6)
- Tissue culture evidence for a circulating neurotoxin in Huntington's chorea (1987) (5)
- STUDIES OF AMINES IN NORMAL AND SCHIZOPHRENIC SUBJECTS11Supported by grants from the Medical Research Council of Canada, and the Multiple Sclerosis Society of Canada. (1967) (5)
- Apparent Absence of Amines in Cerebrospinal Fluid of Phenylketonurics (1961) (5)
- Mild elevations of plasma ornithine in homocystinuria. (1981) (4)
- Urinary Excretion of β-Amino-isobutyric Acid in Mongolism (1959) (4)
- A syndrome resembling Friedreich's ataxia with relapsing polyneuropathy and hyperalaninemia. (1968) (4)
- Phenylketonuria and glutamine. (1970) (4)
- Isoniazid and Huntington's chorea. (1978) (4)
- Tyrosinemia and Intractable Seizures (1984) (4)
- Isolation and identification of gamma-aminobutyryl-cystathionine from human brain and CSF. (1977) (4)
- 5-HYDROXYTRYPTOPHAN ADMINISTRATION IN PHENYLKETONURIA. (1964) (4)
- Unrecognized maternal biochemical disease: an uncommon cause of mental retardation in children. (2008) (3)
- LACTIC ACIDOSIS DUE TO A DEFECT IN PYRUVATE METABOLISM IN 3 SIBLINGS (1974) (3)
- End the arms race: Fund human needs (1987) (3)
- Urinary excretion of trace metals in multiple sclerosis (1965) (3)
- Excitatory Amino Acid Receptors in Human Spinal Cord Evaluation in Amyotrophic Lateral Sclerosis Patients a (1992) (3)
- Rats chronically injected with urine from Huntington's chorea patients do not incur striatal damage (1981) (2)
- An unusual aminoacidopathy associated with mitochondrial encephalomyopathy (1989) (2)
- The biochemical basis of mental dysfunction. I. Mental disease (dysmentia). (1957) (2)
- Inability to produce a model of dialysis encephalopathy in the rat by aluminum administration (1987) (2)
- [The biochemical of mental dysfunction. II. Mental deficiency (amentia)]. (1958) (2)
- Is a circulating neurotoxin involved in the pathogenesis of Huntington's chorea? (1985) (2)
- Brain γ-aminobutyric acid and benzodiazepine receptor binding in dialysis encephalopathy (1985) (2)
- Use of the polyethylene glycol adduct of l-asparaginase for the treatment of hyperasparaginemia in a schizophrenic patient (1985) (1)
- The biochemical autopsy: a tool for studies of genetically-determined brain disorders (1977) (1)
- Peacemaking in the 1990s: A Guide for Canadians (1992) (1)
- Cystine, sulfate, and ALS (1991) (1)
- Cystathioninuria in two healty siblings. (1968) (1)
- Elevation of gamma-aminobutyric acid in human brain may increase dopaminergic neuronal function. (1984) (1)
- Homocystinuria (1963) (1)
- Brain gamma-aminobutyric acid deficiency in dialysis encephalopathy. (1985) (1)
- The Prevention of nuclear war : proceedings of a symposium held at the University of British Columbia, March 5-6, 1983 (1983) (0)
- Imprisonment of Cuban doctor (1991) (0)
- Isoniazid therapy for Huntington disease (1981) (0)
- Proceedings of a conference on nuclear war: The search for solutions (1985) (0)
- Urinary excretion of beta-amino-isobutyric acid in mongolism. (1959) (0)
- Rats chronically injected with urine from Huntington's chorea patients do not striatal damage. (1981) (0)
- The Road to Peace (1989) (0)
- Letter: G.A.B.A. in Huntington's chorea. (1974) (0)
- Nuclear war : the search for solutions : proceedings of a conference held at the University of British Columbia, October 19-21, 1984, with special essays (1985) (0)
- Nuclear War: The Search for Solutions (1988) (0)
- Brain gamma-aminobutyric acid and benzodiazepine receptor binding in dialysis encephalopathy. (1985) (0)
- INH therapy (1979) (0)
- War protest by Canadian researcher. (1970) (0)
- End the arms race : fund human needs : proceedings of the 1986 Vancouver Centennial Peace and Disarmament Symposium (1986) (0)
- Global peace as a professional concern, I (1989) (0)
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