Tadhg Begley
#118,970
Most Influential Person Now
Irish chemist
Tadhg Begley's AcademicInfluence.com Rankings
Download Badge
Chemistry
Tadhg Begley's Degrees
- Bachelors Chemistry National University of Ireland
- PhD Chemistry National University of Ireland
Why Is Tadhg Begley Influential?
(Suggest an Edit or Addition)According to Wikipedia, Tadhg P. Begley is an Irish chemist and Distinguished Professor, Robert A. Welch Foundation Chair and Derek Barton Chair of Chemistry at Texas A&M University, and also a published author of books. His honors include Elected Fellow of the American Association for the Advancement of Science, National Institutes of Health Merit Award, National University of Chemistry Honorary D.Sc.
Tadhg Begley's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- The Subsystems Approach to Genome Annotation and its Use in the Project to Annotate 1000 Genomes (2005) (1887)
- Top down characterization of larger proteins (45 kDa) by electron capture dissociation mass spectrometry. (2002) (328)
- Thiamin biosynthesis in prokaryotes (1999) (265)
- The structural and biochemical foundations of thiamin biosynthesis. (2009) (260)
- High-resolution solution structures of oxidized and reduced Escherichia coli thioredoxin. (1994) (230)
- NAD biosynthesis: identification of the tryptophan to quinolinate pathway in bacteria. (2003) (189)
- The biosynthesis of coenzyme A in bacteria. (2001) (188)
- Top‐down MS, a powerful complement to the high capabilities of proteolysis proteomics (2007) (178)
- Wiley encyclopedia of chemical biology (2009) (157)
- Phenoxazinone synthase: mechanism for the formation of the phenoxazinone chromophore of actinomycin. (1989) (143)
- Structure of oxalate decarboxylase from Bacillus subtilis at 1.75 A resolution. (2002) (140)
- Crystal Structure of Mammalian Cysteine Dioxygenase (2006) (134)
- Saccharomyces cerevisiae THI4p is a suicidal thiamin thiazole synthase (2010) (130)
- The crystal structure and mechanism of orotidine 5'-monophosphate decarboxylase. (2000) (130)
- Reconstitution of ThiC in thiamine pyrimidine biosynthesis expands the radical SAM superfamily. (2008) (129)
- Biosynthesis of the thiazole moiety of thiamin pyrophosphate (vitamin B1). (2003) (125)
- Thiamin Biosynthesis in Escherichia coli (1998) (116)
- The biosynthesis of nicotinamide adenine dinucleotides in bacteria. (2001) (115)
- The Antibiotic Activity of N-Pentylpantothenamide Results from Its Conversion to Ethyldethia-Coenzyme A, a Coenzyme A Antimetabolite* (2002) (115)
- Discovery of a SAR11 growth requirement for thiamin’s pyrimidine precursor and its distribution in the Sargasso Sea (2014) (112)
- Reconstitution and biochemical characterization of a new pyridoxal-5'-phosphate biosynthetic pathway. (2005) (112)
- Crystal structure and mechanism of tryptophan 2,3-dioxygenase, a heme enzyme involved in tryptophan catabolism and in quinolinate biosynthesis. (2007) (110)
- Structural and mechanistic studies on ThiO, a glycine oxidase essential for thiamin biosynthesis in Bacillus subtilis. (2003) (103)
- Structural biology of enzymes of the thiamin biosynthesis pathway. (2003) (101)
- Biosynthesis of the thiazole moiety of thiamin in Escherichia coli: Identification of an acyldisulfide-linked protein–protein conjugate that is functionally analogous to the ubiquitin/E1 complex (2001) (100)
- Mechanistic studies of a protonolytic organomercurial cleaving enzyme: bacterial organomercurial lyase. (1986) (100)
- Aerobic tryptophan degradation pathway in bacteria: novel kynurenine formamidase. (2003) (100)
- The enzymology of sulfur activation during thiamin and biotin biosynthesis. (1999) (99)
- Solution structure of ThiS and implications for the evolutionary roots of ubiquitin (2001) (96)
- A new thiamin salvage pathway. (2007) (95)
- Structure of the Escherichia coli ThiS-ThiF complex, a key component of the sulfur transfer system in thiamin biosynthesis. (2006) (92)
- Reconstitution of a new cysteine biosynthetic pathway in Mycobacterium tuberculosis. (2005) (92)
- Spore Photoproduct Lyase from Bacillus subtilis Spores Is a Novel Iron-Sulfur DNA Repair Enzyme Which Shares Features with Proteins such as Class III Anaerobic Ribonucleotide Reductases and Pyruvate-Formate Lyases (1998) (91)
- Inhibitors of Pantothenate Kinase: Novel Antibiotics for Staphylococcal Infections (2003) (90)
- Structural studies on 3-hydroxyanthranilate-3,4-dioxygenase: the catalytic mechanism of a complex oxidation involved in NAD biosynthesis. (2005) (88)
- PHOTOENZYMES : A NOVEL CLASS OF BIOLOGICAL CATALYSTS (1994) (87)
- Efficient sequence analysis of the six gene products (7‐74 kDA) from the escherichia coli thiamin biosynthetic operon by tandem high‐resolution mass spectrometry (1998) (83)
- Anaerobic biosynthesis of the lower ligand of vitamin B12 (2015) (83)
- Phosphopantothenoylcysteine Synthetase from Escherichia coli (2001) (81)
- Phenoxazinone synthase: enzymatic catalysis of an aminophenol oxidative cascade (1988) (81)
- Stoichiometry and spectroscopic identity of copper centers in phenoxazinone synthase: a new addition to the blue copper oxidase family. (1993) (80)
- A putative Fe2+-bound persulfenate intermediate in cysteine dioxygenase. (2008) (79)
- Bacterial organomercurial lyase: overproduction, isolation, and characterization. (1986) (78)
- Structural insights into the mechanism of the PLP synthase holoenzyme from Thermotoga maritima. (2006) (75)
- Pyridoxal phosphate: biosynthesis and catabolism. (2011) (74)
- Top down characterization of secreted proteins from Mycobacterium tuberculosis by electron capture dissociation mass spectrometry (2003) (73)
- Crystal structure of 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate kinase from Salmonella typhimurium at 2.3 A resolution. (2002) (72)
- Menaquinone biosynthesis: formation of aminofutalosine requires a unique radical SAM enzyme. (2013) (71)
- Protochlorophyllide reductase. 1. Determination of the regiochemistry and the stereochemistry of the reduction of protochlorophyllide to chlorophyllide (1989) (70)
- Biosynthesis of the thiamin pyrimidine: the reconstitution of a remarkable rearrangement reaction. (2004) (67)
- Picosecond Laser Photolysis Studies on the Photorepair of Pyrimidine Dimers by DNA Photolyase. 1. Laser Photolysis of Photolyase-2-Deoxyuridine Dinucleotide Photodimer Complex (1991) (67)
- Structural characterization of the regulatory proteins TenA and TenI from Bacillus subtilis and identification of TenA as a thiaminase II. (2005) (67)
- The mechanism of action of bacimethrin, a naturally occurring thiamin antimetabolite. (2001) (65)
- Crystal structure of 4-methyl-5-beta-hydroxyethylthiazole kinase from Bacillus subtilis at 1.5 A resolution. (2000) (65)
- Tryptophan Catabolism: Identification and Characterization of a New Degradative Pathway (2005) (64)
- Biosynthesis of thiamin thiazole in eukaryotes: conversion of NAD to an advanced intermediate. (2007) (64)
- Biosynthesis of F0, precursor of the F420 cofactor, requires a unique two radical-SAM domain enzyme and tyrosine as substrate. (2012) (60)
- Alternatives to vitamin B1 uptake revealed with discovery of riboswitches in multiple marine eukaryotic lineages (2014) (60)
- EPR spectroscopic and computational characterization of the hydroxyethylidene-thiamine pyrophosphate radical intermediate of pyruvate:ferredoxin oxidoreductase. (2006) (59)
- The biosynthesis and degradation of thiamin (vitamin B1). (1996) (58)
- The biosynthesis of the thiazole phosphate moiety of thiamin: the sulfur transfer mediated by the sulfur carrier protein ThiS. (2004) (57)
- Functional copper at the acetyl-CoA synthase active site (2003) (56)
- A Genetic Screen for the Identification of Thiamin Metabolic Genes* (2004) (55)
- Radical S-Adenosylmethionine (SAM) Enzymes in Cofactor Biosynthesis: A Treasure Trove of Complex Organic Radical Rearrangement Reactions* (2014) (52)
- Mechanistic studies on the repair of a novel DNA photolesion: the spore photoproduct. (1999) (52)
- Cofactor biosynthesis: an organic chemist's treasure trove. (2006) (51)
- Dibenzothiophene Catabolism Proceeds via a Flavin-N5-oxide Intermediate. (2016) (50)
- Identification of the Two Missing Bacterial Genes Involved in Thiamine Salvage: Thiamine Pyrophosphokinase and Thiamine Kinase (2004) (50)
- Thiamine deficiency in Cambodian infants with and without beriberi. (2012) (49)
- The mechanism of inactivation of 3-hydroxyanthranilate-3,4-dioxygenase by 4-chloro-3-hydroxyanthranilate. (2005) (49)
- The pyridine ring of NAD is formed by a nonenzymatic pericyclic reaction. (2005) (48)
- Biosynthesis of the Thioquinolobactin Siderophore: an Interesting Variation on Sulfur Transfer (2007) (47)
- Enzymatic reactions involving novel mechanisms of carbanion stabilization. (2004) (47)
- Identification of the Escherichia coliNicotinic Acid Mononucleotide Adenylyltransferase Gene (2000) (46)
- Characterization of Two Kinases Involved in Thiamine Pyrophosphate and Pyridoxal Phosphate Biosynthesis in Bacillus subtilis: 4-Amino-5-Hydroxymethyl-2-Methylpyrimidine Kinase and Pyridoxal Kinase (2004) (45)
- Substrate analogues as mechanistic probes of methyl-S-coenzyme M reductase. (1987) (45)
- Vitamin B1 de novo synthesis in the human malaria parasite Plasmodium falciparum depends on external provision of 4-amino-5-hydroxymethyl-2-methylpyrimidine (2006) (45)
- Mechanistic Studies on Thiaminase I (1996) (44)
- Three-dimensional Structure of YaaE from Bacillus subtilis, a Glutaminase Implicated in Pyridoxal-5′-phosphate Biosynthesis* (2004) (44)
- O-phospho-L-serine and the thiocarboxylated sulfur carrier protein CysO-COSH are substrates for CysM, a cysteine synthase from Mycobacterium tuberculosis. (2008) (44)
- Investigations into the Biosynthesis, Regulation, and Self‐Resistance of Toxoflavin in Pseudomonas protegens Pf‐5 (2015) (43)
- Thiamin biosynthesis in eukaryotes: characterization of the enzyme-bound product of thiazole synthase from Saccharomyces cerevisiae and its implications in thiazole biosynthesis. (2006) (43)
- BIOSYNTHESIS OF THIAMIN I : THE FUNCTION OF THE THIE GENE PRODUCT (1995) (43)
- Biosynthesis of Branched Alkoxy Groups: Iterative Methyl Group Alkylation by a Cobalamin-Dependent Radical SAM Enzyme. (2017) (43)
- A Maize Thiamine Auxotroph Is Defective in Shoot Meristem Maintenance[C][W][OA] (2010) (43)
- Catalysis of a new ribose carbon-insertion reaction by the molybdenum cofactor biosynthetic enzyme MoaA. (2013) (43)
- The Organic Chemistry of Biological Pathways (2005) (43)
- Structural similarities between thiamin-binding protein and thiaminase-I suggest a common ancestor. (2008) (42)
- The biosynthesis of the thiazole phosphate moiety of thiamin (vitamin B1): the early steps catalyzed by thiazole synthase. (2004) (41)
- Structural characterization of the enzyme-substrate, enzyme-intermediate, and enzyme-product complexes of thiamin phosphate synthase. (2001) (41)
- A "radical dance" in thiamin biosynthesis: mechanistic analysis of the bacterial hydroxymethylpyrimidine phosphate synthase. (2010) (41)
- Tryptophan Lyase (NosL): Mechanistic Insights from Substrate Analogues and Mutagenesis. (2015) (41)
- Overexpression, purification and characterization of two pyrimidine kinases involved in the biosynthesis of thiamin: 4-amino-5-hydroxymethyl-2-methylpyrimidine kinase and 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate kinase (1998) (40)
- Mechanistic studies on phosphopantothenoylcysteine decarboxylase. (2001) (40)
- CHEMICAL AND ENZYMATIC SYNTHESIS OF 1-DEOXY-D-XYLULOSE-5-PHOSPHATE (1998) (40)
- Crystal structure of thiamin phosphate synthase from Bacillus subtilis at 1.25 A resolution. (1999) (40)
- Overexpression of recombinant proteins with a C‐terminal thiocarboxylate: Implications for protein semisynthesis and thiamin biosynthesis (1998) (40)
- Cofactor biosynthesis--still yielding fascinating new biological chemistry. (2008) (39)
- Structure of the PLP degradative enzyme 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase from Mesorhizobium loti MAFF303099 and its mechanistic implications. (2009) (39)
- Thiamin pyrimidine biosynthesis in Candida albicans : a remarkable reaction between histidine and pyridoxal phosphate. (2012) (39)
- Structural insights into the function of the thiamin biosynthetic enzyme Thi4 from Saccharomyces cerevisiae. (2006) (38)
- Trapping and Electron Paramagnetic Resonance Characterization of the 5′dAdo• Radical in a Radical S-Adenosyl Methionine Enzyme Reaction with a Non-Native Substrate (2019) (37)
- Mechanistic studies on phosphopantothenoylcysteine decarboxylase: trapping of an enethiolate intermediate with a mechanism-based inactivating agent. (2004) (37)
- Formation of the chromophore of the pyoverdine siderophores by an oxidative cascade. (2003) (37)
- Thiamin biosynthesis: still yielding fascinating biological chemistry. (2012) (36)
- Mechanistic studies on thiamin phosphate synthase: evidence for a dissociative mechanism. (2001) (36)
- DNA-protein cross-linking: model systems for pyrimidine-aromatic amino acid cross-linking. (2006) (35)
- Structure of human phosphopantothenoylcysteine synthetase at 2.3 A resolution. (2003) (35)
- Thiamin biosynthesis in Bacillus subtilis: structure of the thiazole synthase/sulfur carrier protein complex. (2004) (35)
- Thiaminase I (42 kDa) heterogeneity, sequence refinement, and active site location from high-resolution tandem mass spectrometry (1995) (35)
- The structural basis for the remarkable catalytic proficiency of orotidine 5'-monophosphate decarboxylase. (2000) (35)
- Crystal structure of thiaminase-I from Bacillus thiaminolyticus at 2.0 A resolution. (1998) (35)
- Biosynthetic Versatility and Coordinated Action of 5′-Deoxyadenosyl Radicals in Deazaflavin Biosynthesis (2015) (34)
- Synthesis of the Dinucleotide Spore Photoproduct (1995) (34)
- A subsystems-based approach to the identification of drug targets in bacterial pathogens. (2007) (34)
- Catalysis of a flavoenzyme-mediated amide hydrolysis. (2010) (34)
- Tryptophan Lyase (NosL): A Cornucopia of 5'-Deoxyadenosyl Radical Mediated Transformations. (2016) (33)
- Detection of four oxidation sites in viral prolyl‐4‐hydroxylase by top‐down mass spectrometry (2003) (32)
- Mechanism-Based Inactivation of the Human Prolyl-4-hydroxylase by 5-Oxaproline-Containing Peptides: Evidence for a Prolyl Radical Intermediate (1999) (32)
- From Suicide Enzyme to Catalyst: The Iron-Dependent Sulfide Transfer in Methanococcus jannaschii Thiamin Thiazole Biosynthesis. (2016) (32)
- Formation of the dimethylbenzimidazole ligand of coenzyme B(12) under physiological conditions by a facile oxidative cascade. (2003) (31)
- Crystal Structure of a Sulfur Carrier Protein Complex Found in the Cysteine Biosynthetic Pathway of Mycobacterium tuberculosis†‡ (2008) (31)
- In vitro reconstitution of the radical S-adenosylmethionine enzyme MqnC involved in the biosynthesis of futalosine-derived menaquinone. (2013) (30)
- RutA-Catalyzed Oxidative Cleavage of the Uracil Amide Involves Formation of a Flavin-N5-oxide. (2017) (29)
- The Vitamin B1 Metabolism of Staphylococcus aureus Is Controlled at Enzymatic and Transcriptional Levels (2009) (28)
- Identification of Modification Sites in Large Biomolecules by Stable Isotope Labeling and Tandem High Resolution Mass Spectrometry (1997) (28)
- Structural studies of thiamin monophosphate kinase in complex with substrates and products. (2008) (27)
- Mechanistic studies on pyridoxal phosphate synthase: the reaction pathway leading to a chromophoric intermediate. (2008) (26)
- 13C NMR snapshots of the complex reaction coordinate of pyridoxal phosphate synthase. (2008) (26)
- Mechanistic studies on DNA photolyase. III, The trapping of the one-bond-cleaved intermediate from a photodimer radical cation model system (1991) (26)
- Comparison of Femtosecond Laser and Continuous Wave UV Sources for Protein–Nucleic Acid Crosslinking (2007) (26)
- Structural and mechanistic studies of HpxO, a novel flavin adenine dinucleotide-dependent urate oxidase from Klebsiella pneumoniae. (2013) (26)
- Two-dimensional mass spectrometry of biomolecules at the subfemtomole level. (1998) (25)
- Aminofutalosine Synthase: Evidence for Captodative and Aryl Radical Intermediates Using β-Scission and SRN1 Trapping Reactions. (2017) (25)
- Thi20, a remarkable enzyme from Saccharomyces cerevisiae with dual thiamin biosynthetic and degradation activities. (2005) (25)
- Isolation of labeled 9-dihydrobaccatin III and related taxoids from cell cultures of taxuscell cultures of taxus canadensis elicited with m. (1999) (24)
- Biosynthesis of the thiamin-thiazole in eukaryotes: identification of a thiazole tautomer intermediate. (2008) (24)
- Non-canonical active site architecture of the radical SAM thiamin pyrimidine synthase (2015) (24)
- The radical SAM enzyme HydE generates adenosylated Fe(I) intermediates en route to the [FeFe]-hydrogenase catalytic H-cluster. (2020) (23)
- Cofactor Biosynthesis: A Mechanistic Perspective (1998) (23)
- Globally Important Haptophyte Algae Use Exogenous Pyrimidine Compounds More Efficiently than Thiamin (2017) (23)
- Novel enzymology in futalosine-dependent menaquinone biosynthesis. (2018) (23)
- RNA-seq Analysis Reveals That an ECF σ Factor, AcsS, Regulates Achromobactin Biosynthesis in Pseudomonas syringae pv. syringae B728a (2012) (23)
- Mechanistic Studies on Tryptophan Lyase (NosL): Identification of Cyanide as a Reaction Product. (2018) (22)
- Mechanistic studies on DNA photolyase. 1. Secondary deuterium isotope effects on the cleavage of 2′-deoxyuridine dinucleotide photodimers (1989) (22)
- Anaerobic 5-Hydroxybenzimidazole Formation from Aminoimidazole Ribotide: An Unanticipated Intersection of Thiamin and Vitamin B₁₂ Biosynthesis. (2015) (22)
- Molybdopterin biosynthesis: trapping an unusual purine ribose adduct in the MoaA-catalyzed reaction. (2013) (22)
- Solid-state NMR and density functional theory studies of ionization states of thiamin. (2011) (21)
- Pseudouridine monophosphate glycosidase: a new glycosidase mechanism. (2012) (21)
- A 5-formyltetrahydrofolate cycloligase paralog from all domains of life: comparative genomic and experimental evidence for a cryptic role in thiamin metabolism (2011) (21)
- Crystal Structure of Mycobacterium tuberculosis Polyketide Synthase 11 (PKS11) Reveals Intermediates in the Synthesis of Methyl-branched Alkylpyrones* (2013) (21)
- Mechanistic studies on DNA photolyase. 4. The enthalpy of cleavage of a model photodimer (1991) (21)
- High-resolution crystal structure of the eukaryotic HMP-P synthase (THIC) from Arabidopsis thaliana. (2013) (20)
- Mechanistic studies on DNA photolyase. 5. Secondary deuterium isotope effects on the cleavage of the uracil photodimer radical cation and anion (1992) (20)
- Structural Basis for Iron-Mediated Sulfur Transfer in Archael and Yeast Thiazole Synthases. (2016) (20)
- Mutagenesis studies on TenA: a thiamin salvage enzyme from Bacillus subtilis. (2008) (20)
- Sensitivity of breast cancer cell lines to recombinant thiaminase I (2010) (20)
- Selective Deprotection Of tert-Butyldimethylsilyl Ether With Lithium Bromide And 18-Crown-6 (1997) (19)
- Reagent for the detection of protein thiocarboxylates in the bacterial proteome: lissamine rhodamine B sulfonyl azide. (2010) (19)
- A Remarkable Oxidative Cascade That Replaces the Riboflavin C8 Methyl with an Amino Group during Roseoflavin Biosynthesis. (2016) (19)
- Molybdopterin Biosynthesis: Trapping of Intermediates for the MoaA-Catalyzed Reaction Using 2′-DeoxyGTP and 2′-ChloroGTP as Substrate Analogues. (2014) (18)
- An assay for thiaminase I in complex biological samples. (2007) (18)
- Cloning, sequencing and regulation of thiA, a thiamin biosynthesis gene from Bacillus subtilis. (1997) (18)
- Protein thiocarboxylate-dependent methionine biosynthesis in Wolinella succinogenes. (2011) (18)
- Stereochemical studies on phosphopantothenoylcysteine decarboxylase from Escherichia coli. (2003) (18)
- A missing enzyme in thiamin thiazole biosynthesis: identification of TenI as a thiazole tautomerase. (2011) (18)
- Flavin-N5-oxide: A new, catalytic motif in flavoenzymology. (2017) (18)
- Application of the intramolecular magnesium-ene reaction to the stereocontrolled total syntheses of (±)-12-acetoxysinularene and (±)-5-epi-12-acetoxysinularene (1984) (18)
- Substrate specificity of human prolyl-4-hydroxylase. (1998) (17)
- The Selectivity for Cysteine over Serine in Coenzyme A Biosynthesis (2005) (17)
- Biosynthesis of the thiamin thiazole in Bacillus subtilis: identification of the product of the thiazole synthase-catalyzed reaction. (2009) (17)
- Glycal formation in crystals of uridine phosphorylase. (2010) (17)
- Simultaneous Kinetic Characterization of Multiple Protein Forms by Top Down Mass Spectrometry (2005) (16)
- Competence of Thiamin Diphosphate-Dependent Enzymes with 2'-Methoxythiamin Diphosphate Derived from Bacimethrin, a Naturally Occurring Thiamin Anti-vitamin. (2016) (16)
- Hexachlorobenzene Catabolism Involves a Nucleophilic Aromatic Substitution and Flavin-N5-Oxide Formation. (2019) (16)
- Thiamin phosphate synthase: the rate of pyrimidine carbocation formation. (2007) (16)
- A novel mechanism of sulfur transfer catalyzed by O-acetylhomoserine sulfhydrylase in the methionine-biosynthetic pathway of Wolinella succinogenes. (2011) (16)
- Structure of trifunctional THI20 from yeast. (2011) (16)
- Trapping of a chromophoric intermediate in the Pdx1-catalyzed biosynthesis of pyridoxal 5'-phosphate. (2008) (16)
- Oxidative cascades: a facile biosynthetic strategy for the assembly of complex molecules. (2005) (15)
- Lysine relay mechanism coordinates intermediate transfer in vitamin B6 biosynthesis. (2017) (15)
- Toxoflavin lyase requires a novel 1-His-2-carboxylate facial triad. (2011) (14)
- Biosynthesis of a Thiamin Antivitamin in Clostridium botulinum (2014) (14)
- Identification of the product of toxoflavin lyase: degradation via a Baeyer-Villiger oxidation. (2012) (14)
- PLP catabolism: identification of the 4-pyridoxic acid dehydrogenase gene in Mesorhizobium loti MAFF303099. (2007) (14)
- Mechanistic studies on CysS - a Vitamin B12-dependent radical SAM methyltransferase involved in the biosynthesis of the t-butyl group of cystobactamid. (2020) (14)
- Reversal of the substrate specificity of CMP N-glycosidase to dCMP. (2013) (13)
- Synthesis of the spore photoproduct (1997) (13)
- Mechanistic studies on prolyl-4-hydroxylase: the vitamin C requiring uncoupled oxidation. (2000) (13)
- A New Synthesis of 1-Deoxy-D-threo-2-pentulose, a Biosynthetic Precursor to the Thiazole Moiety of Thiamin (1995) (12)
- HMP binding protein ThiY and HMP-P synthase THI5 are structural homologues. (2010) (12)
- Domain organization in Candida glabrata THI6, a bifunctional enzyme required for thiamin biosynthesis in eukaryotes. (2010) (12)
- Construction of a thiamin sensor from the periplasmic thiamin binding protein. (2011) (12)
- Synthesis of the Dinucleotide Spore Photoproduct. (1996) (12)
- Gene identification and structural characterization of the pyridoxal 5'-phosphate degradative protein 3-hydroxy-2-methylpyridine-4,5-dicarboxylate decarboxylase from mesorhizobium loti MAFF303099. (2007) (12)
- Structure determination and characterization of the vitamin B6 degradative enzyme (E)-2-(acetamidomethylene)succinate hydrolase. (2010) (12)
- Mechanistic Studies on Thiaminase I: Identification of the Product of Thiamin Degradation in the Absence of the Nucleophilic Cosubstrate (2000) (12)
- PLP catabolism: identification of the 2-(Acetamidomethylene)succinate hydrolase gene in Mesorhizobium loti MAFF303099. (2008) (12)
- Biochemistry: Molecular cannibalism (2007) (11)
- Mechanistic Studies on Thiaminase I OVEREXPRESSION AND IDENTIFICATION OF THE ACTIVE SITE NUCLEOPHILE* (1996) (11)
- Comparison of Thiaminase Activity in Fish Using the Radiometric and 4-Nitrothiophenol Colorimetric Methods (2010) (11)
- Identification of the First Riboflavin Catabolic Gene Cluster Isolated from Microbacterium maritypicum G10* (2016) (11)
- Biochemical characterization of the HpxO enzyme from Klebsiella pneumoniae, a novel FAD-dependent urate oxidase. (2009) (11)
- Design of a cleavable linker for the synthesis of a cis-syn pyrimidine photodimer. (1992) (10)
- Burkholderia glumae ToxA Is a Dual-Specificity Methyltransferase That Catalyzes the Last Two Steps of Toxoflavin Biosynthesis. (2016) (10)
- beta-scission of the N-O bond in alkyl hydroxamate radicals: a fast radical trap. (2000) (10)
- Biosynthesis of thiamin thiazole: determination of the regiochemistry of the S/O acyl shift by using 1,4-dideoxy-D-xylulose-5-phosphate. (2006) (10)
- Protein posttranslational modifications: chemistry, biology, and applications. (2011) (10)
- Mechanistic studies on DNA photolyase. 9. Is the cleavage of the cyclobutane pyrimidine photodimer radical anion a pericyclic reaction (1993) (10)
- Mechanistic Studies on the Radical SAM Enzyme Tryptophan Lyase (NosL). (2018) (9)
- Structure of a Clostridium botulinum C143S thiaminase I/thiamin complex reveals active site architecture . (2013) (9)
- Antibacterial Strategy against H. pylori: Inhibition of the Radical SAM Enzyme MqnE in Menaquinone Biosynthesis. (2019) (9)
- Mechanistic studies on protochlorophyllide reductase : a model system for the enzymatic reaction (1992) (9)
- Mechanistic studies on DNA photolyase VIII: Studies on the fragmentation of the radical anion and cation of a uracil-alkene photoadduct (1993) (9)
- Structural basis for antibiotic action of the B1 antivitamin 2′-methoxy-thiamine (2020) (9)
- Crystallization and preliminary X-ray analysis of thiaminase I from Bacillus thiaminolyticus: space group change upon freezing of crystals. (1998) (8)
- An efficient enzymatic synthesis of thiamin pyrophosphate. (2003) (8)
- Mechanistic Studies on Thiaminase I. 3. Stereochemistry of the Thiaminase I and the Bisulfite-Catalyzed Degradation of Chiral Monodeuteriothiamin. (1996) (8)
- 5.15 – Thymine Dimer Photochemistry: A Mechanistic Perspective (1999) (8)
- Mechanistic Studies on Thiaminase I: 1. The Stereochemical Course of the Reaction (1995) (8)
- Protochlorophyllide Reductase III: Synthesis of a Protochlorophyllide‐Dihydroflavin Complex (1996) (8)
- Active-site models for complexes of quinolinate synthase with substrates and intermediates. (2013) (8)
- Biosynthesis of Thiamin Pyrophosphate. (2009) (7)
- Synthesis of 32P-labeled intermediates on the purine biosynthetic pathway (2002) (7)
- Chemical biology: an educational challenge for chemistry departments (2005) (6)
- An Aminoimidazole Radical Intermediate in the Anaerobic Biosynthesis of the 5,6-Dimethylbenzimidazole Ligand to Vitamin B12. (2018) (6)
- Chemical and Enzymatic Synthesis of 1-Deoxy-D-xylulose-5-phosphate. (2010) (6)
- Phenoxazinone Synthase: Enzymatic Catalysis of an Aminophenol Oxidative Cascade. (1988) (5)
- Molybdopterin biosynthesis-Mechanistic studies on a novel MoaA catalyzed insertion of a purine carbon into the ribose of GTP. (2015) (5)
- Menaquinone Biosynthesis: Biochemical and Structural Studies of Chorismate Dehydratase. (2019) (5)
- Structural studies on 3-hydroxyanthranilate-3,4-dioxygenase (2005) (5)
- Aminofutalosine Synthase (MqnE): A New Catalytic Motif in Radical SAM Enzymology. (2018) (5)
- Iterative Methylations Resulting in the Biosynthesis of the t-Butyl Group Catalyzed by a B12-Dependent Radical SAM Enzyme in Cystobactamid Biosynthesis. (2018) (5)
- Biochemical Characterization and Structural Basis of Reactivity and Regioselectivity Differences between Burkholderia thailandensis and Burkholderia glumae 1,6-Didesmethyltoxoflavin N-Methyltransferase. (2017) (4)
- β-Scission of the N—O Bond in Alkyl Hydroxamate Radicals: A Fast Radical Trap. (2000) (4)
- Menaquinone Biosynthesis: New Strategies to Trap Radical Intermediates in the MqnE-Catalyzed Reaction. (2021) (4)
- 7.15 – Thiamin Biosynthesis (2010) (4)
- 4-Amino-5-hydroxymethyl-2-methylpyrimidine Phosphate Kinase from Salmonella typhimurium complexed with 4-Amino-5-hydroxymethyl-2-methylpyrimidine (2002) (4)
- Flavin-N5-oxide intermediates in dibenzothiophene, uracil, and hexachlorobenzene catabolism. (2019) (4)
- Cofactor Biosynthesis: An Organic Chemist′s Treasure Trove (2006) (3)
- 4-Amino-5-hydroxymethyl-2-methylpyrimidine Phosphate Kinase from Salmonella typhimurium (2002) (3)
- Biocatalysis and biotransformation Enzymology in the genomics era (2003) (3)
- Mechanistic and Structural Studies on Thiamine Biosynthetic Enzymes (2003) (3)
- Bacterial organomercury lyase: a protonolytic detoxification catalyst (1987) (3)
- Cysteine Dealkylation in Bacillus subtilis by a Novel Flavin-Dependent Monooxygenase. (2022) (3)
- Metabolomic analysis of microorganisms. (2008) (3)
- Biochemistry: Origin of a key player in methane biosynthesis (2017) (3)
- Protochlorophyllide Reductase. Part 1. Determination of the Regiochemistry and the Stereochemistry of the Reduction of Protochlorophyllide to Chlorophyllide. (1989) (3)
- Mechanistic studies on DNA photolyase, II. Is the blue enzyme isolated from Escherichia coli a mutant? (1991) (2)
- Overexpression, Purification and Characterization of Two Pyrimidine Kinases Involved in the Biosynthesis of Thiamin: 4-Amino-5-hydroxymethyl-2-methylpyrimidine Kinase and 4-Amino-5-hydroxymethyl-2-methylpyrimidine Phosphate Kinase. (2010) (2)
- Crystal Structure of Oxalate Decarboxylase (2002) (2)
- Coenzyme and Prosthetic Group Biosynthesis (2009) (2)
- Design of a Cleavable Linker for the Synthesis of a cis‐syn‐Pyrimidine Photodimer. (1992) (2)
- 7.18 – Cofactor Catabolism (2010) (2)
- Structure of the PLP synthase Holoenzyme from Thermotoga maritima (2007) (1)
- Mechanistic Studies on the Single-Turnover Yeast Thiamin Pyrimidine Synthase: Characterization of the Inactive Enzyme. (2022) (1)
- 7.01 – Overview and Introduction (2010) (1)
- Crystal Structure of E-2-(Acetamidomethylene)succinate Hydrolase (2010) (1)
- CRYSTAL STRUCTURE OF THIAZOLE KINASE MUTANT (C198S) (2000) (1)
- Photoenzymes: A Novel Class of Biological Catalysts (1995) (1)
- Menaquinone Biosynthesis: The Mechanism of 5,8-Dihydroxy-2-naphthoate Synthase (MqnD). (2021) (1)
- Mechanistic studies on thiamin formation and degradation: Thiaminase I and thiamin phosphate synthase (1998) (1)
- 1.5 A Resolution Crystal Structure of Recombinant R. Norvegicus Cysteine Dioxygenase (2006) (1)
- Crystal structure of C. albicans Thi5 H66G mutant (2012) (1)
- Trapping of an oxocarbenium ion intermediate in UP crystals (2010) (1)
- Pyridoxal Phosphate Biosynthesis (2010) (1)
- Natural product biosynthesis--a Renaissance. (2013) (1)
- Characterization of TenA from Bacillus subtilis: a thiaminase II (2005) (1)
- Three-dimensional Structure of YaaE from Bacillus subtilis (2004) (1)
- Crystal structure of Arabidopsis thaliana ThiC with bound aminoimidazole ribonucleotide, 5'-deoxyadenosine, L-methionine, Fe4S4 cluster and Fe (2015) (0)
- Substrate analogues as mechanistic probes of methyl coenzyme m reductase from methanobacterium thermoautotrophicumdelta h (1986) (0)
- Crystal structure of Arabidopsis thaliana ThiC with bound imidazole ribonucleotide and Fe (2015) (0)
- Complex of ThiO (glycine oxidase) with acetyl-glycine (2003) (0)
- New Catalytic Motifs in Flavoenzymology (2020) (0)
- Crystal Structure of 2-Methyl-3-hydroxypyridine-5-carboxylic acid Oxygenase with substrate bound (2009) (0)
- Crystal structure of Bacillus subtilis TenA Y112F mutant complexed with formyl aminomethyl pyrimidine (2007) (0)
- Radiosynthesis of 5-[18F]Fluoro-1,2,3-triazoles through Aqueous Iodine–[18F]Fluorine Exchange Reaction (2021) (0)
- Crystal structure of Burkholderia glumae ToxA with bound S-adenosylhomocysteine (SAH) and 1,6-didemethyltoxoflavin (2016) (0)
- Acknowledgment of Reviewers 2013 (2013) (0)
- Discovery of a SAR 11 growth requirement for thiamin ’ s pyrimidine precursor and its distribution in the Sargasso Sea Running title : SAR 11 requires HMP (2014) (0)
- Selective Deprotection of tert-Butyldimethylsilyl Ether with Lithium Bromide and 18-Crown-6. (1997) (0)
- Mec + Peptidase ( Mycobacterium tuberculosis ) (2013) (0)
- Crystal structure of Arabidopsis thaliana Pdx1K166R-preI320 complex (2017) (0)
- Crystal structure of Burkholderia thailandensis 1,6-didemethyltoxoflavin-N1-methyltransferase with bound S-adenosylhomocysteine (2017) (0)
- Crystal Structure of Mesorhizobium loti 3-hydroxy-2-methylpyridine-4,5-dicarboxylate decarboxylase (2007) (0)
- Complex of Bacillus subtilis TenA with 4-amino-2-methyl-5-hydroxymethylpyrimidine (2005) (0)
- Crystal structure of Caulobacter crescentus ThiC complexed with HMP-P (2008) (0)
- Crystal structure of 3-hydroxyanthranilate-3,4-dioxygenase from Ralstonia metallidurans (2005) (0)
- THIOREDOXIN (REDUCED DITHIO FORM), NMR, 20 STRUCTURES (1996) (0)
- CRYSTAL STRUCTURE OF THIAZOLE KINASE MUTANT (C198S) WITH ATP AND THIAZOLE PHOSPHATE. (2000) (0)
- Crystal Structure of Riboflavin Lyase (RcaE) with modified FMN and substrate Riboflavin (2018) (0)
- The Crystal Structure of Candida glabrata THI6, a Bifunctional Enzyme involved in Thiamin Biosyhthesis of Eukaryotes (2010) (0)
- Acknowledgment of Reviewers 2014 (2014) (0)
- Crystal Structure of Klebsiella pneumoniae R204Q HpxO complexed with FAD (2012) (0)
- Oxidative Dearomatization of PLP in Thiamin Pyrimidine Biosynthesis in Candida albicans. (2023) (0)
- Crystal structure of the flavin oxygenase with cofactor bound involved in folate catabolism (2020) (0)
- Structure of E. coli Uridine Phosphorylase complexed with uracil and ribose 1-phosphate (2005) (0)
- Crystal structure of C. albicans Thi5 complexed with PLP (2012) (0)
- Structure of TenA from Bacillus subtilis (2005) (0)
- Gene identification and structural characterization of the PLP degradative protein 3-hydroxy-2-methylpyridine-4,5-dicarboxylate decarboxylase from Mesorhizobium loti MAFF303099 (2008) (0)
- CB&DD Editorial Advisory Board (fourth in series) (2006) (0)
- Trapping and structural characterisation of a covalent intermediate in vitamin B6 biosynthesis catalysed by the Pdx1 PLP synthase (2021) (0)
- Crystal Structure of Flavin monooxygenase CmoJ (earlier YtnJ) bound with FMN (2018) (0)
- Crystal structure of MilB complexed with cytidine 5'-monophosphate (2013) (0)
- AaThiL complexed with ADP and TPP (2008) (0)
- Crystal Structure of Toxoflavin Lyase (TflA) (2011) (0)
- Crystal Structure of a flavoenzyme RutA in the pyrimidine catabolic pathway (2017) (0)
- Crystal Structure of Klebsiella pneumoniae HpxO complexed with FAD and uric acid (2012) (0)
- Structure of Clostridium botulinum CMP N-glycosidase, BcmB (2013) (0)
- 17. Sappho's Gymnasium (2018) (0)
- Crystal structure of eukaryotic THIC from A. thaliana (2013) (0)
- Structure of the thiazole synthase/ThiS complex (2004) (0)
- Structure of MilB Streptomyces rimofaciens CMP N-glycosidase (2013) (0)
- Crystal Structure of Toxoflavin Lyase (TflA) bound to Mn(II) and Toxoflavin (2011) (0)
- Crystal Structure of Klebsiella pneumoniae HpxO complexed with FAD (2012) (0)
- CRYSTAL STRUCTURE OF HYDROXYETHYLTHIAZOLE KINASE IN THE R3 FORM WITH HYDROXYETHYLTHIAZOLE (2000) (0)
- Crystal Structure of Thiazole Synthase in Saccharomyces cerevisiae at 1.82 A resolution (2006) (0)
- Identification of protein ubiquitination sites (2011) (0)
- CRYSTAL STRUCTURE OF OROTIDINE 5'-MONOPHOSPHATE DECARBOXYLASE FROM BACILLUS SUBTILIS COMPLEXED WITH UMP (2000) (0)
- Crystal structure of Arabidopsis thaliana Pdx1-I320 complex from multiple crystals (2017) (0)
- Crystal structure of Mycobacterium tuberculosis CysM, the cysteine synthase B (2008) (0)
- Preface (2020) (0)
- Crystal Structure of Pseudouridine Monophosphate Glycosidase/Linear Pseudouridine 5'-Phosphate Adduct (2012) (0)
- Crystal Structure of Toxoflavin Lyase (TflA) bound to Mn(II) (2011) (0)
- Crystal Structure of apo Flavin monooxygenase CmoJ (earlier YtnJ) (2018) (0)
- Structural and Mechanistic Studies of HpxO, a Novel FAD-dependent Urate Oxidase from Klebsiella pneumoniae †,‡ (2013) (0)
- Crystal Structure of Phosphopantothenoylcysteine Synthetase (2003) (0)
- Structure of TenI from Bacillus subtilis (2005) (0)
- Structure of ThiO (glycine oxidase) from Bacillus subtilis (2003) (0)
- Synthesis of the Spore Photoproduct. (1997) (0)
- AaThiL complexed with ATP (2008) (0)
- Clostridium botulinum thiaminase I in complex with thiamin (2013) (0)
- Crystal Structure of Riboflavin Lyase (RcaE) with cofactor FMN (2018) (0)
- Crystal structure of Burkholderia glumae ToxA Y7F mutant with bound S-adenosylhomocysteine (SAH) and toxoflavin (2016) (0)
- FOCUS :N OVEL APPROACHES TO PEPTIDE AND PROTEIN STRUCTURE Simultaneous Kinetic Characterization of Multiple Protein Forms by Top Down Mass Spectrometry (2005) (0)
- AaThiL complexed with AMPPCP and TMP (2008) (0)
- Crystal structure of Arabidopsis thaliana ThiC with bound aminoimidazole ribonucleotide, S-adenosylhomocysteine, Fe4S4 cluster and Fe (2015) (0)
- CRYSTAL STRUCTURE OF HYDROXYETHYLTHIAZOLE KINASE IN R3 SPACE GROUP (2000) (0)
- Mechanistic Studies on DNA Photolyase. Part 3. The Trapping of the One- Bond-Cleaved Intermediate from a Photodimer Radical Cation Model System. (1992) (0)
- Crystal structure of Arabidopsis thaliana ThiC with bound imidazole ribonucleotide, S-adenosylhomocysteine, Fe4S4 cluster and Zn (monoclinic crystal form) (2015) (0)
- Bispecific, Cleavable, Protein DNA Crosslinker, Psoralen-Diol-Nitroveratrole. A Probe of Bacteriophage Structure (1983) (0)
- Crystal structure of Burkholderia glumae ToxA with bound S-adenosylhomocysteine (SAH) (2016) (0)
- Crystal structure of Caulobacter crescentus ThiC complexed with imidazole ribonucleotide (2008) (0)
- Crystal Structure of 2-Methyl-3-hydroxypyridine-5-carboxylic acid Oxygenase (2009) (0)
- The Selectivity for Cysteine over Serine in Coenzyme A Biosynthesis (0)
- Crystal structure of the flavin oxygenase with cofactor and substrate bound involved in folate catabolism (2020) (0)
- Investigation of the Iterative Methylations by a Cobalamin‐Dependent Radical SAM Methyltransferase (2018) (0)
- Crystal structure of Burkholderia thailandensis 1,6-didemethyltoxoflavin-N1-methyltransferase with bound 1,6-didemethyltoxoflavin and S-adenosylhomocysteine (2017) (0)
- Crystal structure of Arabidopsis thaliana Pdx1-I320-G3P complex (2017) (0)
- THIOREDOXIN (OXIDIZED DISULFIDE FORM), NMR, 20 STRUCTURES (1996) (0)
- Crystal structure of Caulobacter crescentus ThiC (2008) (0)
- Retraction notice to "Comparison of thiaminase activity in fish using the radiometric and 4-nitrothiophenol colorimetric methods" [J. Great Lakes Res. 36 (2010) 641-645]. (2022) (0)
- Periplasmic N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine binding protein from Bacillus halodurans (2010) (0)
- Structures of E. coli Uridine Phosphorylase (2005) (0)
- A New Synthesis of 1‐Deoxy‐D‐threo‐2‐pentulose, a Biosynthetic Precursor to the Thiazole Moiety of Thiamin. (1995) (0)
- Crystal Structure of Oxalate Decarboxylase Formate Complex (2002) (0)
- Quinolinate synthase from Pyrococcus furiosus (2008) (0)
- AaThiL complexed with AMPPCP (2008) (0)
- Crystal Structure of Bacillus subtilis Thiamin Phosphate Synthase Complexed with a Carboxylated Thiazole Phosphate (2011) (0)
- Structural studies of quinolinate synthase (2005) (0)
- Crystal structure of 3-hydroxyanthranilate-3,4-dioxygenase from Ralstonia metallidurans complexed with 3-hydroxyanthranilic acid (2005) (0)
- Eleven Thematic Meetings within the National Meeting Every Day (2003) (0)
- Crystal Structure of Bacillus subtilis Thiamin Phosphate Synthase K159A (2011) (0)
- Crystal structure of Caulobacter crescentus ThiC with Fe4S4 cluster at remote site (holo form) (2015) (0)
- Crystal Structure of Riboflavin Lyase (RcaE) (2018) (0)
- Synthesis of Methyl-branched ( PKS 11 ) Reveals Intermediates in the Polyketide Synthase 11 tuberculosis Mycobacterium Crystal Structure of Protein Structure and Folding : (2013) (0)
- One enzyme for two radical reactions: Deciphering the mechanism of a novel radical SAM enzyme critical for F-420 cofactor biosynthesis (2013) (0)
- Crystal Structure of Pseudouridine Monophosphate Glycosidase/Linear R5P Adduct (2012) (0)
- Crystal Structure of Pseudouridine Monophosphate Glycosidase Complexed with Pseudouridine 5'-phosphate (2012) (0)
- Crystal structure of tryptophan 2,3-dioxygenase from Ralstonia metallidurans (2006) (0)
- Crystal structure of Mycobacterium tuberculosis CysO, an antigen (2008) (0)
- Crystal structure of MqnA complexed with 3-hydroxybenzoic acid (2019) (0)
- SOLUTION STRUCTURE OF THIS, THE SULFUR CARRIER PROTEIN IN E.COLI THIAMIN BIOSYNTHESIS (2001) (0)
- Trapping a novel intermediate of vitamin B6 biosynthesis in PLP synthase, using in crystallo spectroscopy (2022) (0)
- Crystal structure of Burkholderia glumae ToxA Y7A mutant with bound S-adenosylhomocysteine (SAH) (2016) (0)
- Crystal structure of Burkholderia glumae ToxA (2016) (0)
- CRYSTAL STRUCTURE OF NATIVE THIAZOLE KINASE IN THE MONOCLINIC FORM (1999) (0)
- Crystal Structure of Pseudouridine Monophosphate Glycosidase Complexed with Sulfate (2012) (0)
- Crystal structure of 3-hydroxyanthranilate-3,4-dioxygenase from Ralstonia metallidurans complexed with 4-chloro-3-hydroxyanthranilic acid and NO (2005) (0)
This paper list is powered by the following services:
Other Resources About Tadhg Begley
What Schools Are Affiliated With Tadhg Begley?
Tadhg Begley is affiliated with the following schools:
