Taekjip Ha
#40,093
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Biophysicist
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Taekjip Haphysics Degrees
Physics
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Physics
Taekjip Ha's Degrees
- PhD Physics University of California, Berkeley
- Bachelors Physics Seoul National University
Why Is Taekjip Ha Influential?
(Suggest an Edit or Addition)According to Wikipedia, Taekjip Ha is a South Korean-born American biophysicist who is currently a Bloomberg Distinguished Professor of Biophysics and Biomedical Engineering at Johns Hopkins University. He was previously the Gutgsell Professor of Physics, at University of Illinois at Urbana-Champaign where he was the principal investigator of Single Molecule Nanometry group. He is also a Howard Hughes Medical Institute investigator.
Taekjip Ha's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Myosin V Walks Hand-Over-Hand: Single Fluorophore Imaging with 1.5-nm Localization (2003) (1815)
- A practical guide to single-molecule FRET (2008) (1784)
- Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics (2010) (1282)
- Probing the interaction between single molecules: fluorescence resonance energy transfer between a single donor and a single acceptor (1996) (1073)
- Analysis of single-molecule FRET trajectories using hidden Markov modeling. (2006) (690)
- Advances in single-molecule fluorescence methods for molecular biology. (2008) (685)
- Nonblinking and long-lasting single-molecule fluorescence imaging (2006) (662)
- A single-molecule study of RNA catalysis and folding. (2000) (652)
- Single-molecule fluorescence resonance energy transfer. (2001) (589)
- Photophysics of fluorescent probes for single-molecule biophysics and super-resolution imaging. (2012) (559)
- Probing single-stranded DNA conformational flexibility using fluorescence spectroscopy. (2004) (506)
- Single-molecule fluorescence spectroscopy of enzyme conformational dynamics and cleavage mechanism. (1999) (472)
- Single-pair fluorescence resonance energy transfer on freely diffusing molecules: observation of Förster distance dependence and subpopulations. (1999) (464)
- Near-complete suppression of quantum dot blinking in ambient conditions. (2004) (439)
- Initiation and re-initiation of DNA unwinding by the Escherichia coli Rep helicase (2002) (436)
- Single-molecule techniques : a laboratory manual (2008) (381)
- Defining Single Molecular Forces Required to Activate Integrin and Notch Signaling (2013) (378)
- Spontaneous intersubunit rotation in single ribosomes. (2008) (376)
- Single-molecule high-resolution imaging with photobleaching. (2004) (375)
- Cytosolic Viral Sensor RIG-I Is a 5'-Triphosphate–Dependent Translocase on Double-Stranded RNA (2009) (353)
- Orientation dependence in fluorescent energy transfer between Cy3 and Cy5 terminally attached to double-stranded nucleic acids (2008) (310)
- Single-molecule three-color FRET. (2004) (304)
- Structural dynamics of individual Holliday junctions (2003) (301)
- Real-Time Observation of RecA Filament Dynamics with Single Monomer Resolution (2006) (288)
- Probing Cellular Protein Complexes via Single Molecule Pull-down (2011) (288)
- Crosstalk between the cGAS DNA sensor and Beclin-1 autophagy protein shapes innate antimicrobial immune responses. (2014) (277)
- Spring-Loaded Mechanism of DNA Unwinding by Hepatitis C Virus NS3 Helicase (2007) (270)
- Multimodal optical sensing and analyte specificity using single-walled carbon nanotubes. (2009) (269)
- Precision and accuracy of single-molecule FRET measurements—a multi-laboratory benchmark study (2017) (258)
- Repetitive shuttling of a motor protein on DNA (2005) (255)
- Fluorescence-Force Spectroscopy Maps Two-Dimensional Reaction Landscape of the Holliday Junction (2007) (250)
- Extreme Bendability of DNA Less than 100 Base Pairs Long Revealed by Single-Molecule Cyclization (2012) (248)
- Extreme conformational diversity in human telomeric DNA. (2005) (239)
- Mg2+-dependent conformational change of RNA studied by fluorescence correlation and FRET on immobilized single molecules (2002) (236)
- Ligand-induced conformational changes observed in single RNA molecules. (1999) (230)
- Roles of RIG-I N-terminal tandem CARD and splice variant in TRIM25-mediated antiviral signal transduction (2008) (230)
- Defocused orientation and position imaging (DOPI) of myosin V. (2006) (220)
- Polarization Spectroscopy of Single Fluorescent Molecules (1999) (218)
- Asymmetric Unwrapping of Nucleosomes under Tension Directed by DNA Local Flexibility (2015) (218)
- Multiple intermediates in SNARE-induced membrane fusion (2006) (212)
- Notch-Jagged complex structure implicates a catch bond in tuning ligand sensitivity (2017) (198)
- Real-time observation of DNA recognition and rejection by the RNA-guided endonuclease Cas9 (2016) (194)
- A four-way junction accelerates hairpin ribozyme folding via a discrete intermediate (2003) (192)
- Antiparallel EmrE exports drugs by exchanging between asymmetric structures (2011) (190)
- Early steps of supported bilayer formation probed by single vesicle fluorescence assays. (2002) (188)
- Following movement of the L1 stalk between three functional states in single ribosomes (2009) (186)
- Evidence for a thermal contribution to emission intermittency in single CdSe/CdS core/shell nanocrystals (1999) (184)
- Vesicle encapsulation studies reveal that single molecule ribozyme heterogeneities are intrinsic. (2004) (182)
- Ultrahigh-resolution optical trap with single-fluorophore sensitivity (2011) (177)
- Fluorescence quenching: A tool for single-molecule protein-folding study. (2000) (175)
- SSB Functions as a Sliding Platform that Migrates on DNA via Reptation (2011) (170)
- A survey of single-molecule techniques in chemical biology. (2007) (170)
- PcrA Helicase Dismantles RecA Filaments by Reeling in DNA in Uniform Steps (2010) (167)
- Quantitative analysis of multilayer organization of proteins and RNA in nuclear speckles at super resolution (2017) (164)
- Single-molecule pull-down for studying protein interactions (2012) (162)
- DNA-binding orientation and domain conformation of the E. coli rep helicase monomer bound to a partial duplex junction: single-molecule studies of fluorescently labeled enzymes. (2004) (160)
- One influenza virus particle packages eight unique viral RNAs as shown by FISH analysis (2012) (157)
- Effects of cytosine modifications on DNA flexibility and nucleosome mechanical stability (2016) (155)
- Single-molecule four-color FRET. (2010) (150)
- Matrix softness regulates plasticity of tumour-repopulating cells via H3K9 demethylation and Sox2 expression (2014) (149)
- Ratiometric measurement and identification of single diffusing molecules (1999) (148)
- SSB protein diffusion on single-stranded DNA stimulates RecA filament formation (2009) (145)
- A rule of seven in Watson-Crick base pairing of mismatched sequences (2012) (143)
- Single-molecule quantum-dot fluorescence resonance energy transfer. (2005) (142)
- Surfaces and orientations: much to FRET about? (2004) (140)
- Dynamic structural rearrangements between DNA binding modes of E. coli SSB protein. (2007) (140)
- Hindered Rotational Diffusion and Rotational Jumps of Single Molecules (1998) (137)
- Fueling protein–DNA interactions inside porous nanocontainers (2007) (136)
- Periodic DNA patrolling underlies diverse functions of Pif1 on R-loops and G-rich DNA (2014) (134)
- Protein-guided RNA dynamics during early ribosome assembly (2014) (134)
- Quantum jumps of single molecules at room temperature (1997) (132)
- An entirely specific type I A-kinase anchoring protein that can sequester two molecules of protein kinase A at mitochondria (2011) (132)
- Direct observation of structure-function relationship in a nucleic acid–processing enzyme (2015) (131)
- Coordinating DNA replication by means of priming loop and differential synthesis rate (2009) (126)
- Human Rad52 binds and wraps single-stranded DNA and mediates annealing via two hRad52–ssDNA complexes (2010) (123)
- SSB diffusion on single stranded DNA stimulates RecA filament formation (2009) (122)
- Complexin and Ca2+ stimulate SNARE-mediated membrane fusion (2008) (121)
- Single-molecule views of protein movement on single-stranded DNA. (2012) (121)
- Monovalent, clickable, uncharged, water-soluble perylenediimide-cored dendrimers for target-specific fluorescent biolabeling. (2011) (120)
- Dissecting metal ion-dependent folding and catalysis of a single DNAzyme. (2007) (119)
- Single-molecule fluorescence methods for the study of nucleic acids. (2001) (118)
- Single-molecule conformational analysis of G-quadruplex formation in the promoter DNA duplex of the proto-oncogene c-kit. (2007) (112)
- Real-time observation of DNA target interrogation and product release by the RNA-guided endonuclease CRISPR Cpf1 (Cas12a) (2018) (112)
- Understanding the photophysics of the spinach-DFHBI RNA aptamer-fluorogen complex to improve live-cell RNA imaging. (2013) (109)
- Membrane specific mapping and colocalization of malarial and host skeletal proteins in the Plasmodium falciparum infected erythrocyte by dual-color near-field scanning optical microscopy. (1997) (108)
- A single vesicle-vesicle fusion assay for in vitro studies of SNAREs and accessory proteins (2012) (108)
- Exploring rare conformational species and ionic effects in DNA Holliday junctions using single-molecule spectroscopy. (2004) (108)
- Observation of internal cleavage and ligation reactions of a ribozyme (2004) (106)
- An Improved Surface Passivation Method for Single-Molecule Studies (2014) (106)
- ATPase‐driven oligomerization of RIG‐I on RNA allows optimal activation of type‐I interferon (2013) (105)
- The role of L1 stalk-tRNA interaction in the ribosome elongation cycle. (2010) (104)
- Single-molecule FRET with total internal reflection microscopy. (2012) (100)
- Acidification of the Oxygen Scavenging System in Single-Molecule Fluorescence Studies: In Situ Sensing with a Ratiometric Dual-Emission Probe (2010) (100)
- A dendritic single-molecule fluorescent probe that is monovalent, photostable, and minimally blinking (2013) (98)
- RecA filament sliding on DNA facilitates homology search (2012) (97)
- Determination of in vivo target search kinetics of regulatory noncoding RNA (2015) (96)
- Fusion pore formation and expansion induced by Ca2+ and synaptotagmin 1 (2013) (95)
- Spectroscopic observation of RNA chaperone activities of Hfq in post-transcriptional regulation by a small non-coding RNA (2007) (94)
- Observing spontaneous branch migration of Holliday junctions one step at a time. (2005) (94)
- MCM Forked Substrate Specificity Involves Dynamic Interaction with the 5′-Tail* (2007) (93)
- Voltage-gated sodium channels assemble and gate as dimers (2017) (88)
- Human Rad52-mediated homology search and annealing occurs by continuous interactions between overlapping nucleoprotein complexes (2008) (88)
- Very fast CRISPR on demand (2020) (86)
- Structural mechanisms of PriA-mediated DNA replication restart (2013) (85)
- The Influenza A Virus PB2, PA, NP, and M Segments Play a Pivotal Role during Genome Packaging (2012) (82)
- Conformational flexibility of four-way junctions in RNA. (2004) (81)
- Single-molecule methods leap ahead (2014) (81)
- Direct imaging of single UvrD helicase dynamics on long single-stranded DNA (2013) (80)
- A single vesicle content mixing assay for SNARE-mediated membrane fusion (2010) (80)
- Tandem Spinach Array for mRNA Imaging in Living Bacterial Cells (2015) (80)
- Real-time observation of the transition from transcription initiation to elongation of the RNA polymerase (2009) (79)
- Structural dynamics and processing of nucleic acids revealed by single-molecule spectroscopy. (2004) (78)
- Mechanisms of improved specificity of engineered Cas9s revealed by single-molecule FRET analysis (2018) (77)
- Activated GTPase movement on an RNA scaffold drives cotranslational protein targeting (2012) (77)
- Single-molecule analysis reveals differential effect of ssDNA-binding proteins on DNA translocation by XPD helicase. (2009) (77)
- The SOSS1 single‐stranded DNA binding complex promotes DNA end resection in concert with Exo1 (2012) (77)
- BLM helicase measures DNA unwound before switching strands and hRPA promotes unwinding reinitiation (2009) (76)
- TEMPORAL FLUCTUATIONS OF FLUORESCENCE RESONANCE ENERGY TRANSFER BETWEEN TWO DYES CONJUGATED TO A SINGLE PROTEIN (1999) (72)
- Engineering of a superhelicase through conformational control (2015) (72)
- Multivector Fluorescence Analysis of the xpt Guanine Riboswitch Aptamer Domain and the Conformational Role of Guanine† (2010) (70)
- Elastic Coupling Between RNA Degradation and Unwinding by an Exoribonuclease (2012) (70)
- Distinct mechanisms regulating mechanical force-induced Ca2+ signals at the plasma membrane and the ER in human MSCs (2014) (69)
- A Coarse-Grained Model of Unstructured Single-Stranded DNA Derived from Atomistic Simulation and Single-Molecule Experiment (2014) (67)
- Dynamic look at DNA unwinding by a replicative helicase (2014) (66)
- Real-time observation of strand exchange reaction with high spatiotemporal resolution. (2011) (66)
- Insight into helicase mechanism and function revealed through single-molecule approaches (2010) (66)
- Single-molecule techniques (2008) (65)
- Tyrosine phosphorylation enhances RAD52-mediated annealing by modulating its DNA binding (2011) (64)
- Preparing sample chambers for single-molecule FRET. (2012) (62)
- Defining Single Molecular Forces Required for Notch Activation Using Nano Yoyo. (2016) (62)
- FRET-based dynamic structural biology: Challenges, perspectives and an appeal for open-science practices (2021) (59)
- Structural dynamics of potassium channel gating revealed by single molecule FRET (2015) (59)
- Natural antisense RNA promotes 3′ end processing and maturation of MALAT1 lncRNA (2016) (58)
- A Price To Pay for Relaxed Substrate Specificity: A Comparative Kinetic Analysis of the Class II Lanthipeptide Synthetases ProcM and HalM2 (2014) (58)
- Rotations of the 2B sub-domain of E. coli UvrD helicase/translocase coupled to nucleotide and DNA binding. (2011) (58)
- Mechanical stress determines the configuration of TGFβ activation in articular cartilage (2021) (57)
- A comparative study of multivariate and univariate hidden Markov modelings in time-binned single-molecule FRET data analysis. (2010) (56)
- Dynamics of Major Histocompatibility Complex Class I Association with the Human Peptide-loading Complex* (2012) (56)
- Direct evidence for sequence-dependent attraction between double-stranded DNA controlled by methylation (2016) (56)
- Ebola Virus Does Not Induce Stress Granule Formation during Infection and Sequesters Stress Granule Proteins within Viral Inclusions (2016) (55)
- A Promiscuous DNA Packaging Machine from Bacteriophage T4 (2011) (55)
- Integrin Molecular Tension within Motile Focal Adhesions. (2015) (55)
- Single molecule nanometronome. (2006) (54)
- Quantitative Fluorescent Labeling of Aldehyde-Tagged Proteins for Single-Molecule Imaging (2012) (54)
- Structure-based model of the stepping motor of PcrA helicase. (2006) (53)
- Stepwise translocation of nucleic acid motors. (2010) (52)
- Nuclear speckle fusion via long-range directional motion regulates speckle morphology after transcriptional inhibition (2019) (51)
- Single molecule analysis reveals three phases of DNA degradation by an exonuclease (2011) (51)
- Measuring DNA mechanics on the genome scale (2020) (50)
- Interhead distance measurements in myosin VI via SHRImP support a simplified hand-over-hand model. (2005) (50)
- Single-Molecule Fluorescence Reveals the Unwinding Stepping Mechanism of Replicative Helicase (2014) (50)
- Nucleosomes undergo slow spontaneous gaping (2015) (49)
- Spider Silk Peptide Is a Compact, Linear Nanospring Ideal for Intracellular Tension Sensing. (2016) (49)
- Single-molecule optical spectroscopy. (2014) (49)
- Ultrafast redistribution of E. coli SSB along long single-stranded DNA via intersegment transfer. (2014) (48)
- Bridging conformational dynamics and function using single-molecule spectroscopy. (2006) (48)
- Dynamic Association of ORCA with Prereplicative Complex Components Regulates DNA Replication Initiation (2012) (47)
- Single-Vesicle Fusion Assay Reveals Munc18-1 Binding to the SNARE Core Is Sufficient for Stimulating Membrane Fusion (2010) (46)
- Stoichiometry and assembly of mTOR complexes revealed by single-molecule pulldown (2014) (46)
- Functional Analysis of Multiple Single-stranded DNA-binding Proteins from Methanosarcina acetivorans and Their Effects on DNA Synthesis by DNA Polymerase BI* (2004) (45)
- Transcription initiation in a single-subunit RNA polymerase proceeds through DNA scrunching and rotation of the N-terminal subdomains. (2008) (44)
- Single-Molecule Analysis and Engineering of DNA Motors. (2020) (44)
- 5′‐Single‐stranded/duplex DNA junctions are loading sites for E. coli UvrD translocase (2010) (43)
- The Telomere Capping Complex CST Has an Unusual Stoichiometry, Makes Multipartite Interaction with G-Tails, and Unfolds Higher-Order G-Tail Structures (2013) (43)
- G-Quadruplex DNA Bound by a Synthetic Ligand is Highly Dynamic (2009) (43)
- Visualization of the nanospring dynamics of the IκBα ankyrin repeat domain in real time (2011) (43)
- Dual-molecule spectroscopy: molecular rulers for the study of biological macromolecules (1996) (43)
- Single Molecule Nanocontainers Made Porous Using a Bacterial Toxin (2009) (42)
- Single-molecule nanometry for biological physics (2013) (42)
- The Euryarchaeota, Nature's Medium for Engineering of Single-stranded DNA-binding Proteins* (2005) (42)
- PriC-mediated DNA Replication Restart Requires PriC Complex Formation with the Single-stranded DNA-binding Protein* (2013) (42)
- Near-field fluorescence microscopy of cells. (1998) (42)
- Detecting intramolecular conformational dynamics of single molecules in short distance range with subnanometer sensitivity. (2011) (41)
- Constructing modular and universal single molecule tension sensor using protein G to study mechano-sensitive receptors (2016) (39)
- ALS/FTLD-Linked Mutations in FUS Glycine Residues Cause Accelerated Gelation and Reduced Interactions with Wild-Type FUS. (2020) (38)
- Fluorescent Lifetime Trajectories of a Single Fluorophore Reveal Reaction Intermediates During Transcription Initiation (2009) (38)
- The preRC protein ORCA organizes heterochromatin by assembling histone H3 lysine 9 methyltransferases on chromatin (2015) (38)
- Watching DNA breath one molecule at a time (2013) (37)
- Effects of DNA replication on mRNA noise (2015) (35)
- Force-fluorescence spectroscopy at the single-molecule level. (2010) (34)
- Allosteric Regulation of E-Cadherin Adhesion* (2015) (34)
- Extreme mechanical diversity of human telomeric DNA revealed by fluorescence-force spectroscopy (2019) (34)
- Plantazolicin is an ultra-narrow spectrum antibiotic that targets the Bacillus anthracis membrane. (2016) (33)
- Kaposi's Sarcoma-Associated Herpesvirus Viral Interferon Regulatory Factor 4 (vIRF4) Targets Expression of Cellular IRF4 and the Myc Gene To Facilitate Lytic Replication (2013) (33)
- Single molecular force across single integrins dictates cell spreading. (2015) (32)
- Single molecule spectroscopy with automated positioning (1997) (31)
- Mimicking Co-Transcriptional RNA Folding Using a Superhelicase. (2018) (30)
- How directional translocation is regulated in a DNA helicase motor. (2007) (30)
- Single-molecule fluorescence microscopy of native macromolecular complexes. (2016) (30)
- Single-Molecule FRET (2001) (30)
- BEND3 represses rDNA transcription by stabilizing a NoRC component via USP21 deubiquitinase (2015) (30)
- Forcing a connection: Impacts of single‐molecule force spectroscopy on in vivo tension sensing (2011) (30)
- Hippocampal AMPA receptor assemblies and mechanism of allosteric inhibition (2021) (29)
- Mapping cell surface adhesion by rotation tracking and adhesion footprinting (2017) (28)
- Conformational model of the Holliday junction transition deduced from molecular dynamics simulations. (2004) (28)
- Antibiotics that bind to the A site of the large ribosomal subunit can induce mRNA translocation. (2013) (28)
- Targeting DNA G-Quadruplexes with Helical Small Molecules (2014) (28)
- TDAG51 deficiency promotes oxidative stress-induced apoptosis through the generation of reactive oxygen species in mouse embryonic fibroblasts (2013) (28)
- Single-molecule studies of DNA and RNA four-way junctions. (2004) (28)
- C2AB: A Molecular Glue for Lipid Vesicles with a Negatively Charged Surface (2009) (28)
- TGFβ1 reinforces arterial aging in the vascular smooth muscle cell through a long-range regulation of the cytoskeletal stiffness (2018) (27)
- Opening–closing dynamics of the mitochondrial transcription pre-initiation complex (2011) (27)
- Real-time observation of DNA recognition and rejection by the RNA-guided endonuclease Cas 9 (2016) (27)
- RNA folding and the origins of catalytic activity in the hairpin ribozyme. (2007) (26)
- Evolution of protein-coupled RNA dynamics during hierarchical assembly of ribosomal complexes (2017) (26)
- Branch migration enzyme as a Brownian ratchet (2008) (26)
- Metals induce transient folding and activation of the Twister ribozyme (2017) (26)
- Discrete and heterogeneous rotational dynamics of single membrane probe dyes in gel phase supported lipid bilayer. (2004) (26)
- Dual-color three-dimensional STED microscopy with a single high-repetition-rate laser. (2015) (26)
- Photodestruction intermediates probed by an adjacent reporter molecule. (2003) (26)
- Structural Mechanisms of Cooperative DNA Binding by Bacterial Single-Stranded DNA-Binding Proteins. (2019) (25)
- Single-Molecule Approaches Embrace Molecular Cohorts (2013) (24)
- Unraveling helicase mechanisms one molecule at a time (2006) (24)
- The SNARE complex from yeast is partially unstructured on the membrane. (2008) (24)
- Real-time monitoring of single ZTP riboswitches reveals a complex and kinetically controlled decision landscape (2020) (24)
- Single-molecule FRET reveals the native-state dynamics of the IκBα ankyrin repeat domain. (2013) (23)
- Cooperative Conformational Transitions Keep RecA Filament Active During ATPase Cycle (2014) (23)
- Labeling DNA (or RNA) for single-molecule FRET. (2012) (22)
- Single-molecule FRET analysis of helicase functions. (2010) (22)
- Single molecule analysis of effects of non-canonical guide RNAs and specificity-enhancing mutations on Cas9-induced DNA unwinding (2019) (22)
- Single molecule analysis of Thermus thermophilus SSB protein dynamics on single-stranded DNA (2013) (22)
- Real-time observation of G-quadruplex dynamics using single-molecule FRET microscopy. (2010) (22)
- Assembly of the five-way junction in the ribosomal small subunit using hybrid MD-Gō simulations. (2012) (21)
- Determinants of target prioritization and regulatory hierarchy for the bacterial small RNA SgrS (2017) (21)
- In Planta Single-Molecule Pull-Down Reveals Tetrameric Stoichiometry of HD-ZIPIII:LITTLE ZIPPER Complexes[OPEN] (2016) (21)
- Single‐molecule pull‐down (SiMPull) for new‐age biochemistry (2014) (21)
- Single-molecule packaging initiation in real time by a viral DNA packaging machine from bacteriophage T4 (2014) (20)
- Temperature-independent porous nanocontainers for single-molecule fluorescence studies. (2010) (20)
- Sphingolipids facilitate age asymmetry of membrane proteins in dividing yeast cells (2017) (20)
- Engineering of Functional Replication Protein A Homologs Based on Insights into the Evolution of Oligonucleotide/ Oligosaccharide-Binding Folds (2008) (19)
- RNA fluorescence in situ hybridization in cultured mammalian cells. (2015) (19)
- Stereospecific effects determine the structure of a four-way DNA junction. (2005) (19)
- Correlating Transcription Initiation and Conformational Changes by a Single-Subunit RNA Polymerase with Near Base-Pair Resolution. (2018) (19)
- Amorphous Lithium Nickel Vanadate Thin-Film Anodes for Rechargeable Lithium Microbatteries (2002) (19)
- A Chemical Controller of SNARE-Driven Membrane Fusion That Primes Vesicles for Ca(2+)-Triggered Millisecond Exocytosis. (2016) (18)
- Erratum: SSB protein diffusion on single-stranded DNA stimulates RecA filament formation (Nature (2009) 461 (1092-1097)) (2009) (18)
- Junction resolving enzymes use multivalency to keep the Holliday junction dynamic (2018) (18)
- Mechanism of polypurine tract primer generation by HIV-1 reverse transcriptase (2017) (18)
- Cas9 deactivation with photocleavable guide RNAs. (2021) (18)
- Nanomechanics and co-transcriptional folding of Spinach and Mango (2019) (17)
- Fight against background noise in stimulated emission depletion nanoscopy (2019) (17)
- The FRET-based structural dynamics challenge -- community contributions to consistent and open science practices (2020) (17)
- E. coli Rep helicase and RecA recombinase unwind G4 DNA and are important for resistance to G4-stabilizing ligands (2020) (17)
- Single-cell analysis of early antiviral gene expression reveals a determinant of stochastic IFNB1 expression (2017) (16)
- Fluorescent Lifetime Trajectories of a Single Fluorophore Reveal Reaction Intermediates During Transcription Initiation (2009) (16)
- Real-time observation of Cas9 postcatalytic domain motions (2020) (16)
- Structural basis for DNA unwinding at forked dsDNA by two coordinating Pif1 helicases (2019) (16)
- Redefining the specificity of phosphoinositide-binding by human PH domain-containing proteins (2020) (16)
- Nanoscale mechanics guides cellular decision making. (2016) (16)
- Real-Time Measurement of Molecular Tension during Cell Adhesion and Migration Using Multiplexed Differential Analysis of Tension Gauge Tethers. (2019) (16)
- Ultrasensitivity of Cell Adhesion to the Presence of Mechanically Strong Ligands (2016) (15)
- Genome oligopaint via local denaturation fluorescence in situ hybridization. (2020) (15)
- Towards a Computational Model of a Methane Producing Archaeum (2014) (15)
- Single-molecule nanopositioning: structural transitions of a helicase-DNA complex during ATP hydrolysis. (2011) (15)
- Kaposi's Sarcoma-Associated Herpesvirus Viral Interferon Regulatory Factor 4 (vIRF4) Perturbs the G1-S Cell Cycle Progression via Deregulation of the cyclin D1 Gene (2015) (14)
- Hexameric helicase G40P unwinds DNA in single base pair steps (2018) (14)
- Single-Molecule Analysis of Lipid-Protein Interactions in Crude Cell Lysates. (2016) (14)
- Single‐molecule imaging reveals the translocation and DNA looping dynamics of hepatitis C virus NS3 helicase (2017) (14)
- Precision and accuracy of single-molecule FRET measurements - a worldwide benchmark study (2017) (14)
- Femtosecond tunneling response of surface plasmon polaritons (1998) (13)
- Supporting Online Material for Spring-Loaded Mechanism of DNA Unwinding by Hepatitis C Virus NS 3 Helicase (2007) (13)
- Streamlining effects of extra telomeric repeat on telomeric DNA folding revealed by fluorescence-force spectroscopy (2019) (13)
- Structural biology: Growth factor rattled out of its cage (2017) (13)
- Multicolor single-molecule FRET for DNA and RNA processes. (2021) (13)
- Probing Nature's Nanomachines One Molecule at a Time. (2016) (12)
- Accurate Background Subtraction in STED Nanoscopy by Polarization Switching (2019) (12)
- Mimicking Co-Transcriptional RNA Folding using a Superhelicase (2018) (12)
- Reversible and controllable nanolocomotion of an RNA-processing machinery. (2010) (12)
- Dynamic Growth and Shrinkage Govern the pH Dependence of RecA Filament Stability (2015) (11)
- Contractility kits promote assembly of the mechanoresponsive cytoskeletal network (2019) (11)
- Membrane ruffling is a mechanosensor of extracellular fluid viscosity (2022) (11)
- Photonics: How nanocrystals lost their blink (2009) (11)
- Biomolecular structures: from isolated molecules to the cell crowded medium. (2010) (11)
- Inching over hurdles: how DNA helicases move on crowded lattices. (2010) (10)
- Prism-type total internal reflection microscopy for single-molecule FRET. (2012) (10)
- Relaxed Rotational and Scrunching Changes in P266L Mutant of T7 RNA Polymerase Reduce Short Abortive RNAs while Delaying Transition into Elongation (2014) (10)
- DNA mechanics and its impact on biological processes. (2021) (10)
- Single-molecule analysis of SSB dynamics on single-stranded DNA. (2012) (9)
- Light-controlled twister ribozyme with single-molecule detection resolves RNA function in time and space (2020) (9)
- Deciphering the mechanical code of genome and epigenome (2020) (9)
- Molecular mechanism of sequence-dependent stability of RecA filament (2013) (9)
- Single-Molecule Studies of ssDNA-Binding Proteins Exchange. (2018) (9)
- A genetically encoded fluorescent tRNA is active in live-cell protein synthesis (2016) (9)
- Objective-type total internal reflection microscopy (emission) for single-molecule FRET. (2012) (8)
- Rotations of the 2 B Subdomain of E . coli UvrD Helicase / Translocase Coupled to Nucleotide and DNA Binding (2011) (8)
- Methanosarcina acetivorans Flap Endonuclease 1 Activity Is Inhibited by a Cognate Single-Stranded-DNA-Binding Protein (2006) (8)
- Water in biological systems. (2010) (8)
- Labeling proteins for single-molecule FRET. (2012) (8)
- DNA mechanics and its biological impact (8)
- Ultraslow relaxation of confined DNA (2014) (8)
- Regeneration of PEG slide for multiple rounds of single molecule measurements. (2021) (8)
- Imaging and identifying impurities in single-molecule FRET studies. (2012) (8)
- Fluorescence Methods for Molecular Biology (2008) (7)
- ORCA/LRWD1 Regulates Homologous Recombination at ALT-Telomeres by Modulating Heterochromatin Organization (2020) (7)
- Just Took a DNA Test, Turns Out 100% Not That Phase. (2020) (7)
- Next generation single-molecule techniques: Imaging, labeling, and manipulation in vitro and in cellulo. (2022) (7)
- Crystal structure and ligand-induced folding of the SAM/SAH riboswitch (2020) (7)
- Flipping nanoscopy on its head (2017) (7)
- Force-dependent trans-endocytosis by breast cancer cells depletes costimulatory receptor CD80 and attenuates T cell activation. (2020) (7)
- Fluorescence spectroscopy of single molecules at room temperature and its applications (1996) (7)
- Probing Single Helicase Dynamics on Long Nucleic Acids Through Fluorescence-Force Measurement. (2017) (7)
- Understanding the Molecular Mechanisms of the CRISPR Toolbox Using Single Molecule Approaches. (2018) (7)
- Need for Speed: Mechanical Regulation of a Replicative Helicase (2007) (7)
- Cdc42-dependent modulation of rigidity sensing and cell spreading in tumor repopulating cells. (2018) (7)
- Functional instability allows access to DNA in longer transcription Activator-Like effector (TALE) arrays (2018) (6)
- Rupture force of cell adhesion ligand tethers modulates biological activities of a cell-laden hydrogel. (2016) (6)
- Effects of individual base-pairs on in vivo target search and destruction kinetics of bacterial small RNA (2021) (6)
- Direct Visualization of Helicase Dynamics Using Fluorescence Localization and Optical Trapping. (2017) (6)
- Single-Molecule Studies of HIV-1 Protease Catalysis Enabled by Chemical Protein Synthesis (2011) (6)
- COL2A1 Is a Novel Biomarker of Melanoma Tumor Repopulating Cells (2020) (6)
- Real-time observation of DNA target interrogation and product release by the RNA-guided endonuclease CRISPR Cpf1 (2017) (6)
- Toward Single-Cell Single-Molecule Pull-Down. (2018) (6)
- Molecular Nanomechanical Mapping of Histamine-Induced Smooth Muscle Cell Contraction and Shortening. (2021) (5)
- DNA nanotechnology: a nanomachine goes live. (2009) (5)
- VMD as a Software for Visualization and Quantitative Analysis of Super Resolution Imaging and Single Particle Tracking (2014) (5)
- The Single-Molecule Centroid Localization Algorithm Improves the Accuracy of Fluorescence Binding Assays. (2018) (5)
- ALS/FTLD-Linked Mutations in FUS Glycine Residues Cause Accelerated Gelation and Reduced Interactions with Wild-Type FUS. (2020) (5)
- Erratum: Monovalent, clickable, uncharged, water-soluble perylenediimide-cored dendrimers for target-specific fluorescent biolabeling (Journal of the American Chemical Society (2011) 131 (9964-9967) DOI: 10.1021/ja2009136) (2011) (5)
- T-Cell Death-Associated Gene 51 Is a Novel Negative Regulator of PPARγ That Inhibits PPARγ-RXRα Heterodimer Formation in Adipogenesis (2020) (5)
- Advances in mass spectrometry for biological science. (2010) (5)
- A viral genome packaging ring-ATPase is a flexibly coordinated pentamer (2021) (5)
- Publisher Correction: Precision and accuracy of single-molecule FRET measurements—a multi-laboratory benchmark study (2018) (5)
- Increasing kinase domain proximity promotes MST2 autophosphorylation during Hippo signaling (2020) (5)
- Erratum: SSB functions as a sliding platform that migrates on DNA via reptation (Cell (2011) 146 (222-232)) (2011) (4)
- Reliability and accuracy of single-molecule FRET studies for characterization of structural dynamics and distances in proteins (2022) (4)
- Strategy for room temperature spectroscopy of single molecules (1997) (4)
- Nuclear speckle fusion via long-range directional motion regulates the number and size of speckles (2018) (4)
- Reverse-chaperoning activity of an AAA+ protein. (2011) (4)
- Characterization and in vitro testing of newly isolated lytic bacteriophages for the biocontrol of Pseudomonas aeruginosa. (2022) (4)
- Massively parallel genomic perturbations with multi-target CRISPR interrogates Cas9 activity and DNA repair at endogenous sites (2022) (4)
- The repeat region of the circumsporozoite protein is an elastic linear spring with a functional role in Plasmodium sporozoite motility (2021) (4)
- Sequence-dependent mechanochemical coupling of helicase translocation and unwinding at single-nucleotide resolution (2022) (4)
- Erratum: Single-molecule chemistry and biology special feature: Fueling protein-DNA interactions inside porous nanocontainers (Proceedings of the National Academy of Sciences of the United States (July 31, 2007) 104: 31 (12646-12650) 10.1073/pnas.0610673104) (2007) (4)
- Control Effects of Imicyafos GR against Two Species of the Root-knot Nematodes (Meloidogyne incognita and Meloidogyne hapla) (2015) (4)
- Coordinated DNA and histone dynamics drive accurate histone H2A.Z exchange (2021) (4)
- DNA sequence and methylation prescribe the inside-out conformational dynamics and bending energetics of DNA minicircles (2021) (4)
- The light side of the force (2016) (4)
- Editorial Overview: Single-Molecule Approaches up to Difficult Challenges in Folding and Dynamics. (2017) (4)
- Cover Picture: Single‐Molecule Quantum‐Dot Fluorescence Resonance Energy Transfer (ChemPhysChem 5/2005) (2005) (3)
- Reversible and Controllable Nanolocomotion of an RNA-Processing Machinery (2010) (3)
- Orc6 is a component of the replication fork and enables efficient mismatch repair (2022) (3)
- Correction to Reversible and Controllable Nanolocomotion of an RNA-Processing Machinery (2013) (3)
- Mechanisms of improved specificity of engineered Cas9s revealed by single-molecule FRET analysis (2017) (3)
- Single Molecule Immuno Pull Down Assay (SiMPull) for Studying Protein-Protein Interactions (2009) (3)
- Single-molecule FRET: Technique and applications to the studies of molecular machines (2011) (3)
- Single-Molecule Imaging Reveals the Translocation Dynamics of Hepatitis C Virus NS3 Helicase (2014) (3)
- Objective-type total internal reflection microscopy (excitation) for single-molecule FRET. (2012) (3)
- A Helicase with an Extra Spring in Its Step (2012) (3)
- Rtt105 regulates RPA function by configurationally stapling the flexible domains (2022) (3)
- Designing a nine cysteine-less DNA packaging motor from bacteriophage T4 reveals new insights into ATPase structure and function. (2014) (3)
- Seeing a molecular machine self-renew (2011) (2)
- Homochirality and the origin of life. Editorial of the PCCP themed issue. (2011) (2)
- Improving the specificity of nucleic acid detection with endonuclease-actuated degradation (2022) (2)
- Streamlining effects of extra telomeric repeat on telomere folding revealed by fluorescence-force spectroscopy (2019) (2)
- Studies on the Mechanisms of Translocation and Termination (2011) (2)
- Stochastic Analysis Demonstrates the Dual Role of Hfq in Chaperoning E. coli Sugar Shock Response (2020) (2)
- Author response: Periodic DNA patrolling underlies diverse functions of Pif1 on R-loops and G-rich DNA (2014) (2)
- Temporal fluctuations in single molecule dipole orientation and single molecule energy transfer as a probe for protein conformational dynamics (1998) (2)
- Fluorescence spectroscopy of single-molecule dynamics and its biological applications (1998) (2)
- Single-Molecule FRET Analysis of Replicative Helicases. (2018) (2)
- Real-time observation of DNA target interrogation and product release by the RNA-guided endonuclease CRISPR Cpf 1 (2017) (2)
- Recent advances in studying mechanical properties of DNA (2012) (2)
- Achieving single nucleotide sensitivity in direct hybridization genome imaging (2022) (1)
- Dynamin forms liquid-like condensates at synapses to support ultrafast endocytosis (2022) (1)
- SSB Functions as a Sliding Platform that Migrates on DNA via Reptation (2011) (1)
- Engineering functional membrane-membrane interface by InterSpy (2022) (1)
- A single-molecule view of chaperonin cooperativity (2011) (1)
- Single-Molecule Imaging: A Collagenase Pauses before Embarking on a Killing Spree (2012) (1)
- Photophysical Properties of the Spinach-DFHBI RNA Aptamer-Fluorogen Complex and its Applications to Live Cell Imaging with Improved Fluorescence Signal (2014) (1)
- Membrane ruffling is a mechanosensor of extracellular fluid viscosity (2022) (1)
- Author response: RecA filament sliding on DNA facilitates homology search (2012) (1)
- Single Molecule Methods for studying CRISPR Cas9-Induced DNA Unwinding. (2021) (1)
- Senescent stroma induces nuclear deformations in cancer cells via the inhibition of RhoA/ROCK/myosin II-based cytoskeletal tension (2021) (1)
- Single Molecule Mechano-Memory (2014) (1)
- Catalytic DNA Polymerization Can Be Expedited by Active Product Release (2022) (1)
- The Study of Single Biomolecules with Fluorescence Methods (2001) (1)
- Searching for sequence features that control DNA flexibility (2020) (1)
- Real-Time Observation of DNA Recognition by the RNA-Guided Endonuclease Cas9 using Single-Molecule FRET (2015) (1)
- Editorial on nanobiology. (2011) (1)
- A parameter estimation method for fluorescence lifetime data (2015) (1)
- ATP binding facilitates target search of SWR1 chromatin remodeler by promoting one-dimensional diffusion on DNA (2022) (1)
- Room temperature study of single molecule dynamics on a surface (1997) (1)
- Single-Molecule Views of Protein Movement on (2012) (1)
- Pseudomonas-tailed lytic phages: genome mechanical analysis and putative correlation with virion morphogenesis yield. (2022) (1)
- Mechanism of Coordination of the Bacteriophage T4 DNA Packaging Motor Analyzed by Real-Time Single Molecule Fluorescence Assay (2016) (1)
- Correction for Cisse et al., Single-Molecule Chemistry and Biology Special Feature: Fueling protein–DNA interactions inside porous nanocontainers (2007) (1)
- ATP binding enhances SWR1 target search by promoting 1D scanning on DNA (2022) (1)
- Improving the sensitivity of in vivo CRISPR off-target detection with DISCOVER-Seq+ (2022) (1)
- Dynamics of Human Telomeric G-Quadruplex Probed by Single Molecule Fluorescence-Force Spectroscopy (2016) (1)
- The START domain potentiates HD-ZIPIII transcriptional activity (2022) (1)
- Single-molecule characterization of subtype-specific β1 integrin mechanics (2022) (1)
- Massively parallel genomic perturbations with multi-target CRISPR reveal new insights on Cas9 activity and DNA damage responses at endogenous sites (2022) (1)
- Probing Protein Diffusion and Dissociation Mechanisms on DNA Using Fluorescence-Force Spectroscopy (2010) (1)
- Erratum: Observation of internal cleavage and ligation reactions of a ribozyme (2004) (1)
- Room temperature observation of quantum jumps of single molecule into dark states (1996) (1)
- AAA + ATPase Thorase inhibits mTOR signaling through the disassembly of the mTOR complex 1 (2022) (1)
- Supplemental data for Initiation and re-initiation of DNA unwinding by the E . coli Rep helicase (2002) (1)
- Bi-allelic TTI1 variants cause an autosomal-recessive neurodevelopmental disorder with microcephaly. (2023) (1)
- Follow ing movement of the L1 stalk between three functional states in single ribosomes. (Proceedings of the National Academy of Sciences of the United States of America (2009) 24:8 (2571-2576) DOI: 10.1073/pnas.0813180106) (2009) (1)
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- Monitoring Single SAM/SAH Riboswitch Ligand-Induced Folding and Mimicking Co-Transcriptional Folding (2021) (0)
- ‘At’ Content as a Determinant of the Chromosome Structure (2014) (0)
- [Illinois] Phys550 Lecture 17: Regulation of Gene Expressions (2013) (0)
- Stepping Mechanism of Bacteriophage T7 Helicase and Priming Loop Observed Using Single-Molecule Fret Methods (2010) (0)
- Orc6 at replication fork enables efficient mismatch repair (2021) (0)
- Dynamics of An Archael DNA Polymerase Revealed By Single Molecule Fret (2010) (0)
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- Fluorescence-Based DNA-Nanotube Platform with Single Molecule Resolution (2011) (0)
- The Princess and the Pea: A Story of Cell Mechanics (2015) (0)
- Single molecule fluorescence study of DNA helicase activity (2000) (0)
- [Illinois] Phys550 Lecture 18: Motor Proteins/Florescence/DNA and 2-State System I (2013) (0)
- Biophysical driving forces of heterochromatin organization (2022) (0)
- Two Distinct Regimes of Integrin Molecular Forces (2015) (0)
- Fast cleavage action unveils 3D dynamics and kinetics of DNA repair in telomeres (2022) (0)
- Measuring DNA mechanics on the genome scale (2020) (0)
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- Modeling the Impact of Point Mutations on the Regulatory Potency of the Small RNA SgrS (2019) (0)
- TGFβ1 reinforces arterial aging in the vascular smooth muscle cell through a long-range regulation of the cytoskeletal stiffness (2018) (0)
- 2009 GEM4 Summer School - University of Illinois at Urbana-Champaign: Lecture 12: Next generation single molecule fluorescence technologies (2010) (0)
- Asymmetric Role of Negative Curvature Lipids on the SNARE Mediated Vesicle Docking and Fusion (2009) (0)
- Plat Single Molecule Fluorescence Imaging at Micromolar Concentrations (2012) (0)
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- [Illinois] Phys550 Lecture 16: Intro to BioPhysics (2013) (0)
- Effector-Free Molecular Mechanism of Epigenetic Regulation Revealed by Molecular Dynamics Simulations and Single-Molecule FRET Experiments (2016) (0)
- [Illinois] Phys550 Lecture 26:Third Generation Sequencing & Gene Expression Analysis Tools (2014) (0)
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- Single Molecule Study Of the RNA Degradation and Polyadenylation Activities of the Archaeal Exosome (2009) (0)
- Dimensional reduction for single-molecule imaging of condensation events (2022) (0)
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- Simultaneous Real-Time Observation of DNA Unwinding and Nuclease Domain Activation in Cas9-RNA-DNA Complex via Three-Color Single Molecule FRET (2018) (0)
- Light activation and deactivation of Cas9 for DNA repair studies. (2021) (0)
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- First Realization of Single-Molecule Four-Color FRET (2011) (0)
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- Dependence of Nucleosome Mechanical Stability on DNA Mismatches and Histone Variants (2022) (0)
- High Throughput Simulations Reveal how Sequence and Methylation Control DNA Looping and Self-Association (2017) (0)
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- Illuminating the elementary steps of helicase translocation and unwinding via single molecule analysis (2008) (0)
- Structural Transitions Of a Helicase-Partial Duplex DNA Complex during ATP Hydrolysis Cycle (2009) (0)
- Single Molecule Content Mixing Analysis of SNARE-Mediated Membrane Fusion (2010) (0)
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- Diffusion Mapping in Living Cells using Camera-Based Correlation Spectroscopy and Phasor Analysis (2016) (0)
- 4D dynamical whole-cell simulations of a growing minimal cell. (2023) (0)
- 1018-Pos Board B773 VMD as a Software for Visualization and Quantitative Analysis of Super Resolution Imaging and Single Particle Tracking (2016) (0)
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- DNA Dynamics During SWR1-Catalyzed H2A.Z Histone Exchange (2021) (0)
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- Evidence for the Interaction of Endophilin 3 with the SK3 Channels in PC12 Cells (2014) (0)
- [Illinois] Physics 550 Biomolecular Physics (2013) (0)
- Rtt105 configurationally staples RPA and blocks facilitated exchange and interactions with RPA-interacting proteins (2022) (0)
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- © 2015 by Mohamed Ghoneim DIRECT REAL-TIME CORRELATION OF PROTEIN CONFORMATION AND SUBSTRATE RECOGNITION BY MOHAMED GHONEIM DISSERTATION (2015) (0)
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- Single-Molecule Analysis of Hepatitis C Virus NS3 Helicase Translocating on Single-Stranded RNA (2014) (0)
- Manipulate single nucleic acid molecules in live cells. (2023) (0)
- [Illinois] Phys550 Lecture 25: Noise in Gene Expression and Sequencing Method (2013) (0)
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- Correction to Multivector Fluorescence Analysis of the xpt Guanine Riboswitch Aptamer Domain and the Conformational Role of Guanine (2010) (0)
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- Rapid isothermal amplification of several kilo base pair linear DNA (2022) (0)
- tertiary interactions in the TPP riboswitch. (2016) (0)
- Correction: RecA filament sliding on DNA facilitates homology search (2013) (0)
- Dimensional Reduction for Single-Molecule Imaging of DNA and Nucleosome Condensation by Polyamines, HP1α and Ki-67 (2023) (0)
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- [Illinois] Phys550 Lecture 1: Introduction to Biomolecular Physics (2013) (0)
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- [Illinois] Phys550 Lecture 22: FRET and Force/Toggle Switch/Repriscillator/Gene Regulation Function (2013) (0)
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- [Illinois] Phys550 Lecture 20: DNA Origami/Encode/DNA Flexibility (2013) (0)
- Construction and Characterization of “Spinach” Array for mRNA Live Cell Imaging (2014) (0)
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- Title Diffusion Mapping in Living Cells using Camera-Based Correlation Spectroscopy and Phasor Analysis Permalink (2016) (0)
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- Coupling of two motors: T7 helicase-primase and DNA polymerase (2009) (0)
- June 2016 From single-molecule spectroscopy to super-resolution imaging of the neuron : a review (2016) (0)
- β2-Integrin Adhesive Bond Tension under Shear Stress Modulates Cytosolic Calcium Flux and Neutrophil Inflammatory Response (2022) (0)
- OBSERVING CONFORMATIONAL CHANGES OF INDIVIDUAL RNA MOLECULES USING CONFOCAL MICROSCOPY (2001) (0)
- Chapter 11 RNA Fluorescence In Situ Hybridization in Cultured Mammalian Cells (2014) (0)
- Multi-target CRISPR for high-throughput studies of double-strand break repair and genetic barcoding at endogenous sites (2022) (0)
- Subtype-specific single-molecule mechanics for integrin activation, mechanotransduction and cytoskeleton remodeling (2022) (0)
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