Tak Wah Mak

Q: What Schools Are Affiliated With Tak Wah Mak

Tak Wah Mak is affiliated with the following schools: University of Wisconsin–Madison, University of Toronto

Tak Wah Mak's AcademicInfluence.com Rankings

Tak Wah Mak

Biology

#407

World Rank

#731

Historical Rank

Immunology

#43

World Rank

#47

Historical Rank

Biochemistry

#265

World Rank

#329

Historical Rank

biology Degrees

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Biology

Why Is Tak Wah Mak Influential?

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According to Wikipedia, Tak Wah Mak, is a Canadian medical researcher, geneticist, oncologist, and biochemist. He first became widely known for his discovery of the T-cell receptor in 1983 and pioneering work in the genetics of immunology. In 1995, Mak published a landmark paper on the discovery of the function of the immune checkpoint protein CTLA-4, thus opening the path for immunotherapy/checkpoint inhibitors as a means of cancer treatment. Mak is also the founder of Agios Pharmaceuticals, whose lead compound, IDHIFA®, was approved by the FDA for acute myeloid leukemia in August 2017, becoming the first drug specifically targeting cancer metabolism to be used for cancer treatment. He has worked in a variety of areas including biochemistry, immunology, and cancer genetics.

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Tak Wah Mak's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Phorbol esters induce differentiation in human malignant T lymphoblasts. (1980) (119)
Complete nucleotide sequence of an infectious clone of Friend spleen focus-forming provirus: gp55 is an envelope fusion glycoprotein. (1983) (94)
Quantitative colony method for tumorigenic cells transformed by two distinct strains of Friend leukemia virus. (1981) (68)
Isolation and induction of erythroleukemic cell lines with properties of erythroid progenitor burst-forming cell (BFU-E) and erythroid precursor cell (CFU-E). (1983) (58)
Tissue morphogenesis and vascular stability require the Frem2 protein, product of the mouse myelencephalic blebs gene. (2005) (57)
Particles with characteristics of leukoviruses in cultures of marrow cells from leukemic patients in remission and relapse. (1974) (51)
Viral-related information in oncornavirus-lik particles isolated from cultures of marrow cells from leukemic patients in relapse and remission. (1975) (50)
High levels of heterodisperse RNAs accumulate in T cells infected with human immunodeficiency virus and in normal thymocytes. (1988) (34)
Single-cell immunofluorescence assay for terminal transferase: Human leukaemic and non-leukaemic cells (1980) (33)
Induction of differentiation in human T-lymphoblastic leukemia cell lines by 12-O-tetradecanoylphorbol 13-acetate (TPA): studies with monoclonal antibodies to T cells. (1982) (31)
Fv-2 locus controls expression of Friend spleen focus-forming virus-specific sequences in normal and infected mice. (1979) (30)
Deoxycytidine kinase and cytosine nucleoside deaminase activities in synchronized cultures of normal rat kidney cells. (1978) (30)
Clonal analysis of early and late stages of erythroleukemia induced by molecular clones of integrated spleen focus-forming virus. (1981) (28)
Morphological, immunological, and biochemical analyses of chicken spleen cells transformed in vitro by reticuloendotheliosis virus strain T. (1982) (27)
Functional significance of glutamate–cysteine ligase modifier for erythrocyte survival in vitro and in vivo (2013) (24)
Human preleukaemia cell culture studies in sideroblastic anaemia. (1976) (23)
Purification of terminal deoxynucleotidyltransferase by oligonucleotide affinity chromatography. (1978) (20)
Detection of genes coding for human differentiation markers by their transient expression after DNA transfer. (1982) (18)
Heterogeneity of human thymocytes and a malignant T-lymphoblast cell line, MOLT-3. (1981) (17)
Regulation of blood cell diferentiation. (1975) (16)
Presence and expression of Friend erythroleukemia virus-related sequences in normal and leukemic mouse tissues. (1979) (15)
Generation of mutant mice lacking surface expression of CD4 or CD8 gene targeting. (1992) (15)
Gene expression in single Reed Sternberg cells of Hodgkin's disease: results from PCR generated single cell cDNA libraries. (1992) (12)
Differential requirement for Apaf1 and Bcl-XL in the regulation of programmed cell death during development (2002) (11)
An approach to human preleukemia using cell culture studies. (1976) (5)
Effect of tetrahydrouridine on the action of 1-beta-D-arabinofuranosylcytosine in synchronized cultures of normal rat kidney cells. (1979) (3)
Phase II trial of pharmacodynamically (PDally)-guided optimal biologic dose titration (OBDT) of sorafenib (S) in combination with metronomic cyclophosphamide (mC) in advanced neuroendocrine tumors (aNET). (2009) (3)
Cellular subclasses in human leukemic hemopoiesis. (1976) (2)
s-Like Particles Isolated from Patients in Relapse and Remission (2016) (0)

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Other Resources About Tak Wah Mak

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What Schools Are Affiliated With Tak Wah Mak?

Tak Wah Mak is affiliated with the following schools:

Tak Wah Mak's Academic­Influence.com Rankings

Why Is Tak Wah Mak Influential?

Tak Wah Mak's Published Works

Published Works

Other Resources About Tak Wah Mak

What Schools Are Affiliated With Tak Wah Mak?

Tak Wah Mak's AcademicInfluence.com Rankings