Takashi Fujita
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Computer Science
Takashi Fujita's Degrees
- PhD Computer Science University of Tokyo
- Masters Computer Science University of Tokyo
- Bachelors Computer Science University of Tokyo
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(Suggest an Edit or Addition)Takashi Fujita's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses (2004) (3914)
- Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses (2006) (3609)
- Shared and Unique Functions of the DExD/H-Box Helicases RIG-I, MDA5, and LGP2 in Antiviral Innate Immunity1 (2005) (1634)
- A new protein containing an SH2 domain that inhibits JAK kinases (1997) (1497)
- Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid–inducible gene-I and melanoma differentiation–associated gene 5 (2008) (1460)
- Cell type-specific involvement of RIG-I in antiviral response. (2005) (1410)
- Lipopolysaccharide Stimulates the MyD88-Independent Pathway and Results in Activation of IFN-Regulatory Factor 3 and the Expression of a Subset of Lipopolysaccharide-Inducible Genes1 (2001) (1173)
- Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4 (2002) (1107)
- Structure and expression of a cloned cDNA for human interleukin-2 (1983) (1082)
- Regulated expression of a gene encoding a nuclear factor, IRF-1, that specifically binds to IFN-β gene regulatory elements (1988) (932)
- Structurally similar but functionally distinct factors, IRF-1 and IRF-2, bind to the same regulatory elements of IFN and IFN-inducible genes (1989) (928)
- Regulating Intracellular Antiviral Defense and Permissiveness to Hepatitis C Virus RNA Replication through a Cellular RNA Helicase, RIG-I (2005) (925)
- Direct triggering of the type I interferon system by virus infection: activation of a transcription factor complex containing IRF‐3 and CBP/p300 (1998) (883)
- Regulation of innate antiviral defenses through a shared repressor domain in RIG-I and LGP2 (2007) (740)
- Control of antiviral defenses through hepatitis C virus disruption of retinoic acid-inducible gene-I signaling. (2005) (597)
- RNA recognition and signal transduction by RIG‐I‐like receptors (2009) (593)
- LGP2 is a positive regulator of RIG-I– and MDA5-mediated antiviral responses (2010) (544)
- The C-terminal regulatory domain is the RNA 5'-triphosphate sensor of RIG-I. (2008) (520)
- Nonself RNA-sensing mechanism of RIG-I helicase and activation of antiviral immune responses. (2008) (507)
- RNA helicase encoded by melanoma differentiation-associated gene 5 is a major autoantigen in patients with clinically amyopathic dermatomyositis: Association with rapidly progressive interstitial lung disease. (2009) (493)
- TIR-containing Adapter Molecule (TICAM)-2, a Bridging Adapter Recruiting to Toll-like Receptor 4 TICAM-1 That Induces Interferon-β* (2003) (454)
- The candidate proto-oncogene bcl-3 encodes a transcriptional coactivator that activates through NF-kappa B p50 homodimers. (1993) (453)
- Evidence for aberrant activation of the interleukin-2 autocrine loop by HTLV-1-encoded p40x and T3/Ti complex triggering (1987) (430)
- Viral and therapeutic control of IFN-beta promoter stimulator 1 during hepatitis C virus infection. (2006) (422)
- Cutting Edge: Influenza A Virus Activates TLR3-Dependent Inflammatory and RIG-I-Dependent Antiviral Responses in Human Lung Epithelial Cells1 (2007) (419)
- Negative regulation of the RIG-I signaling by the ubiquitin ligase RNF125 (2007) (413)
- A structural basis for discriminating between self and nonself double-stranded RNAs in mammalian cells (2006) (392)
- Independent modes of transcriptional activation by the p50 and p65 subunits of NF-kappa B. (1992) (365)
- Absence of the type I IFN system in EC cells: Transcriptional activator (IRF-1) and repressor (IRF-2) genes are developmentally regulated (1990) (364)
- Viral Infections Activate Types I and III Interferon Genes through a Common Mechanism* (2007) (359)
- Viral RNA detection by RIG-I-like receptors. (2015) (343)
- The p65 subunit of NF-kappa B regulates I kappa B by two distinct mechanisms. (1993) (325)
- RIG‐I‐like receptors: cytoplasmic sensors for non‐self RNA (2011) (322)
- Induction of endogenous IFN-α and IFN-β genes by a regulatory transcription factor, IRF-1 (1989) (311)
- Function of RIG-I-like Receptors in Antiviral Innate Immunity* (2007) (310)
- Evidence for a nuclear factor(s), IRF‐1, mediating induction and silencing properties to human IFN‐beta gene regulatory elements. (1988) (309)
- Negative regulation of interferon-regulatory factor 3–dependent innate antiviral response by the prolyl isomerase Pin1 (2006) (309)
- Critical Role of an Antiviral Stress Granule Containing RIG-I and PKR in Viral Detection and Innate Immunity (2012) (308)
- Recognition of viral nucleic acids in innate immunity (2010) (298)
- Induction of IRF‐3/‐7 kinase and NF‐κB in response to double‐stranded RNA and virus infection: common and unique pathways (2001) (294)
- NS1 protein of influenza A virus inhibits the function of intracytoplasmic pathogen sensor, RIG-I. (2007) (289)
- Co-ordinated Role of TLR3, RIG-I and MDA5 in the Innate Response to Rhinovirus in Bronchial Epithelium (2010) (287)
- Induction of the transcription factor IRF-1 and interferon-beta mRNAs by cytokines and activators of second-messenger pathways. (1989) (276)
- Structural mechanism of RNA recognition by the RIG-I-like receptors. (2008) (261)
- The bcl-3 proto-oncogene encodes a nuclear I kappa B-like molecule that preferentially interacts with NF-kappa B p50 and p52 in a phosphorylation-dependent manner (1993) (255)
- Identification of Ser-386 of Interferon Regulatory Factor 3 as Critical Target for Inducible Phosphorylation That Determines Activation* (2004) (222)
- Autoimmune disorders associated with gain of function of the intracellular sensor MDA5. (2014) (219)
- Antiviral activity of human OASL protein is mediated by enhancing signaling of the RIG-I RNA sensor. (2014) (212)
- Regulation of human interleukin-2 gene: Functional DNA sequences in the 5′ flanking region for the gene expression in activated T lymphocytes (1986) (206)
- Solution Structures of Cytosolic RNA Sensor MDA5 and LGP2 C-terminal Domains (2009) (203)
- The Alpha/Beta Interferon Response Controls Tissue Tropism and Pathogenicity of Poliovirus (2005) (200)
- A20 Is a Negative Regulator of IFN Regulatory Factor 3 Signaling1 (2005) (198)
- Activation of IFN-beta element by IRF-1 requires a posttranslational event in addition to IRF-1 synthesis. (1991) (191)
- Antiviral innate immunity and stress granule responses (2014) (183)
- Unique structure of murine interleukin-2 as deduced from cloned cDNAs (1985) (181)
- Inhibition of RIG-I-Dependent Signaling to the Interferon Pathway during Hepatitis C Virus Expression and Restoration of Signaling by IKKε (2005) (180)
- A variety of microbial components induce tolerance to lipopolysaccharide by differentially affecting MyD88-dependent and -independent pathways. (2002) (178)
- Virus-Infection or 5′ppp-RNA Activates Antiviral Signal through Redistribution of IPS-1 Mediated by MFN1 (2010) (176)
- Aicardi-Goutières syndrome is caused by IFIH1 mutations. (2014) (170)
- Anti-CADM-140/MDA5 autoantibody titer correlates with disease activity and predicts disease outcome in patients with dermatomyositis and rapidly progressive interstitial lung disease (2013) (168)
- X-ray crystal structure of IRF-3 and its functional implications (2003) (161)
- Interferon-β gene regulation: Tandemly repeated sequences of a synthetic 6 bp oligomer function as a virus-inducible enhancer (1987) (161)
- Delimitation and properties of DNA sequence: required for the regulated expression of human interferon-β gene (1985) (159)
- Identification of Loss of Function Mutations in Human Genes Encoding RIG-I and MDA5 (2009) (155)
- Functional IRF3 deficiency in a patient with herpes simplex encephalitis (2015) (155)
- NAK-Associated Protein 1 Participates in Both the TLR3 and the Cytoplasmic Pathways in Type I IFN Induction1 (2006) (151)
- RIG-I family RNA helicases: cytoplasmic sensor for antiviral innate immunity. (2007) (149)
- The NF‐kappa B p50 precursor, p105, contains an internal I kappa B‐like inhibitor that preferentially inhibits p50. (1992) (147)
- Detection of activated T cell products in the rheumatoid joint using cDNA probes to Interleukin-2 (IL-2) IL-2 receptor and IFN-gamma. (1988) (146)
- Structure of the human interleukin 2 gene. (1983) (146)
- Review: Control of IRF-3 Activation by Phosphorylation (2002) (141)
- Hepatitis C virus NS4B protein targets STING and abrogates RIG‐I–mediated type I interferon‐dependent innate immunity (2013) (134)
- Encephalomyocarditis Virus Disrupts Stress Granules, the Critical Platform for Triggering Antiviral Innate Immune Responses (2013) (134)
- Ubiquitin-Dependent and -Independent Roles of E3 Ligase RIPLET in Innate Immunity (2018) (130)
- Homodimer of Two F-box Proteins βTrCP1 or βTrCP2 Binds to IκBα for Signal-dependent Ubiquitination* (2000) (130)
- DHX36 Enhances RIG-I Signaling by Facilitating PKR-Mediated Antiviral Stress Granule Formation (2014) (123)
- Control of IRF-3 activation by phosphorylation. (2002) (117)
- Direct Involvement of CREB-binding Protein/p300 in Sequence-specific DNA Binding of Virus-activated Interferon Regulatory Factor-3 Holocomplex* (2002) (115)
- Induction of endogenous IFN-alpha and IFN-beta genes by a regulatory transcription factor, IRF-1. (1989) (112)
- Sensing viral invasion by RIG-I like receptors. (2014) (95)
- Interferon stimulation creates chromatin marks and establishes transcriptional memory (2018) (95)
- The oncogenic transcription factor IRF-2 possesses a transcriptional repression and a latent activation domain. (1994) (94)
- Type III Interferon Restriction by Porcine Epidemic Diarrhea Virus and the Role of Viral Protein nsp1 in IRF1 Signaling (2017) (92)
- Short-interfering RNAs induce retinal degeneration via TLR3 and IRF3. (2012) (86)
- Analyses of virus-induced homomeric and heteromeric protein associations between IRF-3 and coactivator CBP/p300. (2000) (85)
- Production of a Dominant-Negative Fragment Due to G3BP1 Cleavage Contributes to the Disruption of Mitochondria-Associated Protective Stress Granules during CVB3 Infection (2013) (84)
- Retinoic acid-inducible gene-I-like receptors. (2011) (83)
- Involvement of a cis-element that binds an H2TF-1/NF kappa B like factor(s) in the virus-induced interferon-beta gene expression. (1989) (82)
- Triggering antiviral response by RIG-I-related RNA helicases. (2007) (77)
- Cytoplasmic nucleic acid sensors in antiviral immunity. (2009) (76)
- Molecular Analysis of the Interleukin‐2 System (1986) (68)
- RIG-I-like receptors and autoimmune diseases. (2015) (68)
- Leader-Containing Uncapped Viral Transcript Activates RIG-I in Antiviral Stress Granules (2016) (68)
- Organization and structure of the mouse interleukin-2 gene. (1984) (64)
- Sequence of a cDNA coding for human IRF-1. (1989) (62)
- Cytoplasmic recognition of RNA. (2008) (54)
- Ser386 phosphorylation of transcription factor IRF‐3 induces dimerization and association with CBP/p300 without overall conformational change (2010) (54)
- PACT, a double-stranded RNA binding protein acts as a positive regulator for type I interferon gene induced by Newcastle disease virus. (2001) (51)
- Regulation of antiviral innate immune responses by RIG-I family of RNA helicases. (2007) (49)
- A Novel Function of Human Pumilio Proteins in Cytoplasmic Sensing of Viral Infection (2014) (48)
- Impaired Antiviral Stress Granule and IFN-β Enhanceosome Formation Enhances Susceptibility to Influenza Infection in Chronic Obstructive Pulmonary Disease Epithelium. (2016) (47)
- IL-1R-Associated Kinase 4 Is Required for Lipopolysaccharide- Induced Activation of APC 1 (2003) (47)
- The 3′ Untranslated Regions of Influenza Genomic Sequences Are 5′PPP-Independent Ligands for RIG-I (2012) (47)
- Involvement of TIRAP/MAL in signaling for the activation of interferon regulatory factor 3 by lipopolysaccharide (2002) (47)
- Homodimer of two F-box proteins betaTrCP1 or betaTrCP2 binds to IkappaBalpha for signal-dependent ubiquitination. (2000) (45)
- PDZ Domain-dependent Suppression of NF-κB/p65-induced Aβ42 Production by a Neuron-specific X11-like Protein* (2000) (45)
- Expression of retinoic acid-inducible gene-I in vascular smooth muscle cells stimulated with interferon-gamma. (2004) (44)
- Hepatitis C virus non-structural proteins responsible for suppression of the RIG-I/Cardif-induced interferon response. (2007) (43)
- Retinoic Acid-inducible Gene I-inducible miR-23b Inhibits Infections by Minor Group Rhinoviruses through Down-regulation of the Very Low Density Lipoprotein Receptor* (2011) (43)
- RIG-I activation inhibits ebolavirus replication. (2009) (43)
- Antiviral Activity of Phenolic Derivatives in Pyroligneous Acid from Hardwood, Softwood, and Bamboo (2018) (40)
- Possible involvement of a cyclic AMP-dependent mechanism in PACAP-induced proliferation and ERK activation in astrocytes. (2003) (39)
- The exp1 gene essential for pileus expansion and autolysis of the inky cap mushroom Coprinopsis cinerea (Coprinus cinereus) encodes an HMG protein. (2008) (39)
- Identification of a germicidal compound against picornavirus in bamboo pyroligneous acid. (2012) (37)
- Analysis of yeast prion aggregates with amyloid-staining compound in vivo. (2003) (36)
- RIG-I-Like Receptors and Type I Interferonopathies. (2017) (34)
- Studies on interferon priming: cellular response to viral and nonviral inducers and requirement of protein synthesis. (1981) (33)
- Amyopathic dermatomyositis developing rapidly progressive interstitial lung disease with elevation of anti-CADM-140/MDA5 autoantibodies (2012) (33)
- Identification and Characterization of BCL-3-binding Protein (2003) (32)
- Expression of IP-10/CXCL10 Is Upregulated by Double-Stranded RNA in BEAS-2B Bronchial Epithelial Cells (2006) (31)
- A nonself RNA pattern: tri-p to panhandle. (2009) (31)
- Involvement of retinoic acid-inducible gene-I in the IFN-γ/STAT1 signalling pathway in BEAS-2B cells (2005) (31)
- Rosmarinic acid is a novel inhibitor for Hepatitis B virus replication targeting viral epsilon RNA-polymerase interaction (2018) (30)
- Sequence of a cDNA coding for human IRF-2. (1989) (30)
- Viral RNA recognition by LGP2 and MDA5, and activation of signaling through step-by-step conformational changes (2020) (30)
- Type I interferon production induced by RIG-I-like receptors. (2010) (30)
- Correction: Critical Role of an Antiviral Stress Granule Containing RIG-I and PKR in Viral Detection and Innate Immunity (2012) (29)
- 5'PPP-RNA induced RIG-I activation inhibits drug-resistant avian H5N1 as well as 1918 and 2009 pandemic influenza virus replication (2010) (29)
- Spatio-temporal characterization of the antiviral activity of the XRN1-DCP1/2 aggregation against cytoplasmic RNA viruses to prevent cell death (2020) (28)
- A novel role for sphingolipid intermediates in activation-induced cell death in T cells (2003) (27)
- Functional Characterization of Domains of IPS-1 Using an Inducible Oligomerization System (2013) (27)
- Priming increases the amount of interferon mRNA in poly(rI).poly(rC)-treated L cells. (1979) (25)
- Mutations in the Cc.rmt1 gene encoding a putative protein arginine methyltransferase alter developmental programs in the basidiomycete Coprinopsis cinerea (2010) (23)
- 55 Amino acid linker between helicase and carboxyl terminal domains of RIG-I functions as a critical repression domain and determines inter-domain conformation. (2011) (23)
- The ASK family kinases differentially mediate induction of type I interferon and apoptosis during the antiviral response (2015) (23)
- Role of the Alpha/Beta Interferon Response in the Acquisition of Susceptibility to Poliovirus by Kidney Cells in Culture (2006) (23)
- Sensing Viral RNA Amid Your Own (2006) (22)
- The Ubiquitin-Like Protein PLIC-1 or Ubiquilin 1 Inhibits TLR3-Trif Signaling (2011) (21)
- Structure-dependent antiviral activity of catechol derivatives in pyroligneous acid against the encephalomycarditis virus (2018) (21)
- GH signalling in pancreatic beta-cells. (1998) (21)
- RIG-I-Like Receptor and Toll-Like Receptor Signaling Pathways Cause Aberrant Production of Inflammatory Cytokines/Chemokines in a Severe Fever with Thrombocytopenia Syndrome Virus Infection Mouse Model (2018) (21)
- Polyinosinic-Polycytidylic Acid Induces the Expression of GRO-α in BEAS-2B Cells (2005) (20)
- Recognition of viruses in the cytoplasm by RLRs and other helicases--how conformational changes, mitochondrial dynamics and ubiquitination control innate immune responses. (2012) (19)
- Cyclophilin inhibitors reduce phosphorylation of RNA-dependent protein kinase to restore expression of IFN-stimulated genes in HCV-infected cells. (2014) (18)
- The p65 subunit of NF-KB regulates IKB by two distinct mechanisms (2007) (18)
- Dysregulation of IFN System Can Lead to Poor Response to Pegylated Interferon and Ribavirin Therapy in Chronic Hepatitis C (2011) (18)
- Fueling Type I Interferonopathies: Regulation and Function of Type I Interferon Antiviral Responses. (2019) (17)
- Aberrant expression of interferon regulatory factor 3 in human lung cancer. (2010) (17)
- Characterization of distinct molecular interactions responsible for IRF3 and IRF7 phosphorylation and subsequent dimerization (2020) (17)
- Impairment of interferon regulatory factor-3 activation by hepatitis C virus core protein basic amino acid region 1. (2012) (17)
- Cellular and genetic analyses of IL-2 production and IL-2 receptor expression in a patient with familial T-cell-dominant immunodeficiency. (1988) (17)
- Autoimmunity caused by constitutive activation of cytoplasmic viral RNA sensors. (2014) (16)
- Antiviral defense: RIG-Ing the immune system to STING. (2009) (16)
- The role of pre‐existing aggregates in Hsp104‐dependent polyglutamine aggregate formation and epigenetic change of yeast prions (2004) (16)
- Endoplasmic reticulum-mediated induction of interleukin-8 occurs by hepatitis B virus infection and contributes to suppression of interferon responsiveness in human hepatocytes. (2018) (16)
- [RIG-I: critical regulator for virus-induced innate immunity]. (2004) (15)
- PDZ domain-dependent suppression of NF-kappaB/p65-induced Abeta42 production by a neuron-specific X11-like protein. (2000) (15)
- Singleton-Merten Syndrome–like Skeletal Abnormalities in Mice with Constitutively Activated MDA5 (2019) (14)
- Characterization of the DNA binding domain of the mouse IRF-2 protein. (1993) (14)
- Functional IRF 3 deficiency in a patient with herpes simplex encephalitis (2015) (14)
- Cytoplasmic double-stranded DNA sensor (2007) (13)
- Production of antiviral substance from sugarcane bagasse by chemical alteration of its native lignin structure through microwave solvolysis. (2020) (13)
- Conversion of Beech Wood into Antiviral Lignin–Carbohydrate Complexes by Microwave Acidolysis (2021) (12)
- PAMPer and tRIGer: ligand-induced activation of RIG-I. (2011) (11)
- Nucleotide sequence of the mouse interferon-β gene (1989) (11)
- Retinoic Acid Inducible Gene I and Protein Kinase R, but Not Stress Granules, Mediate the Proinflammatory Response to Yellow Fever Virus (2020) (11)
- Critical Role of Interferon-α Constitutively Produced in Human Hepatocytes in Response to RNA Virus Infection (2014) (10)
- The Non-structural Protein NSs of SFTSV Causes Cytokine Storm Through the Hyper-activation of NF-κB. (2020) (10)
- LGP2 in Antiviral Innate Immunity DExD/H-Box Helicases RIG-I, MDA5, and Shared and Unique Functions of the (2005) (10)
- Expression of prolactin receptor mRNA in the abdominal gland of the newt Cynops ensicauda. (2004) (10)
- RLRs and TLRs Signaling Pathways Cause Aberrant Production of Inflammatory 1 Cytokines / Chemokines in an SFTSV Infection Mouse Model 2 3 (2018) (10)
- A Plant-Derived Nucleic Acid Reconciles Type I IFN and a Pyroptotic-like Event in Immunity against Respiratory Viruses (2017) (10)
- [Virus-induced expression of type I interferon genes]. (2004) (9)
- Polyinosinic-polycytidylic acid induces the expression of GRO-alpha in BEAS-2B cells. (2005) (9)
- Foreign RNA Induces the Degradation of Mitochondrial Antiviral Signaling Protein (MAVS): The Role of Intracellular Antiviral Factors (2012) (9)
- Cochlear supporting cells function as macrophage-like cells and protect audiosensory receptor hair cells from pathogens (2020) (9)
- Human Lung Epithelial Cells RIGI-Dependent Antiviral Responses in TLR 3-Dependent Inflammatory and Cutting Edge : Influenza A Virus Activates (2007) (8)
- Circumvention of Chaperone Requirement for Aggregate Formation of a Short Polyglutamine Tract by the Co-expression of a Long Polyglutamine Tract* (2002) (8)
- Aicardi-Goutières syndrome-like encephalitis in mutant mice with constitutively active MDA5. (2020) (8)
- DOUBLE-STRANDED RNA STIMULATES THE EXPRESSION OF MONOCYTE CHEMOATTRACTANT PROTEIN-1 IN BEAS-2B BRONCHIAL EPITHELIAL CELLS (2005) (8)
- Antiviral activity of human oligoadenylate synthetases-like (OASL) is mediated by enhancing retinoic acid-inducible gene I (RIG-I) signaling (2014) (8)
- The Role of Non-Structural Protein NSs in the Pathogenesis of Severe Fever with Thrombocytopenia Syndrome (2021) (7)
- Establishment of a novel hepatitis B virus culture system using immortalized human hepatocytes (2020) (7)
- Influence of Genes Suppressing Interferon Effects in Peripheral Blood Mononuclear Cells during Triple Antiviral Therapy for Chronic Hepatitis C (2015) (7)
- Virus-induced expression of retinoic acid inducible gene-I and melanoma differentiation-associated gene 5 in the cochlear sensory epithelium. (2013) (7)
- Structure of mouse interferon stimulated gene factor 3 gamma (ISGF3 gamma/p48) cDNA and chromosomal localization of the gene. (1996) (6)
- Influenza virus NS1- C/EBPβ gene regulatory complex inhibits RIG-I transcription. (2020) (6)
- Virology. Sensing viral RNA amid your own. (2006) (6)
- Screening for inhibitor of episomal DNA identified dicumarol as a hepatitis B virus inhibitor (2019) (6)
- Correction: Leader-Containing Uncapped Viral Transcript Activates RIG-I in Antiviral Stress Granules (2016) (5)
- Establishment of a human hepatocellular cell line capable of maintaining long-term replication of hepatitis B virus (2017) (5)
- Structure of Mouse Interferon Stimulated Gene Factor 3γ(ISGF3γ/ p48) cDNA and Chromosomal Localization of the Gene (1996) (5)
- Interleukin-2 and its receptor: structure and functional expression of the genes. (1986) (5)
- Restoration of type I interferon signaling in intrahepatically primed CD8+ T cells promotes functional differentiation (2021) (5)
- Lymphocyte-stromal cell interaction induces IL-7 expression by interferon regulatory factors. (2013) (4)
- Structure and expression of a cloned cDNA for human interleukin-2. 1983. (1992) (4)
- Cytoplasmic Viral RNA Sensors: RIG-I-Like Receptors (2016) (4)
- Expression of FTZ‐F1α in transgenic Xenopus embryos and oocytes (2002) (4)
- Psoriasis-like skin disorder in transgenic mice expressing a RIG-I Singleton-Merten syndrome variant. (2020) (4)
- [Three dimensional structure of IRF-3 and its implication in signal transduction]. (2004) (3)
- [Non-self RNA-sensing mechanism of RIG-I RNA helicase]. (2008) (3)
- Adsorptive Inhibition of Enveloped Viruses and Nonenveloped Cardioviruses by Antiviral Lignin Produced from Sugarcane Bagasse via Microwave Glycerolysis. (2022) (3)
- Influenza A virus NS1 optimises virus infectivity by enhancing genome packaging in a dsRNA-binding dependent manner (2020) (3)
- Priming Phosphorylation of TANK-Binding Kinase 1 by IκB Kinase β Is Essential in Toll-Like Receptor 3/4 Signaling (2019) (3)
- Identification of a new autoinhibitory domain of interferon-beta promoter stimulator-1 (IPS-1) for the tight regulation of oligomerization-driven signal activation. (2019) (3)
- A NEW PROTEIN SYNTHESIS IS REQUIRED IN PRIMING BY INTERFERON (1980) (3)
- Lysophosphatidic acid induces ME180 cell migration via its putative receptor GPR87 (2015) (2)
- Broad and systemic immune-modulating capacity of plant-derived dsRNA. (2019) (2)
- Structure and Regulation of the Genes Encoding Interleukin-2 and its Receptor (1986) (2)
- HBV upregulates TRAIL-R3 expression in hepatocytes for escaping both cell apoptosis and suppression of their replication by TRAIL. (2022) (2)
- Receptors in Antiviral Immunity (2014) (2)
- Cytoplasmic Sensing of Viral Double-Stranded RNA and Activation of Innate Immunity by RIG-I-Like Receptors (2012) (2)
- The RNA helicase DDX3 promotes IFNB transcription via enhancing IRF-3/p300 holocomplex binding to the IFNB promoter (2022) (2)
- Priming phosphorylation of TBK1 by IKKβ is essential in TLR3/4 signaling. (2019) (2)
- Multiplicative computation in a visual neuron sensitive to looming (2002) (2)
- [Structural and functional views of the intracellular viral RNA sensor RIG-I]. (2008) (2)
- Regulation of cytokine gene expression: gene activation in type I IFN and IL-2 systems. (1988) (2)
- [Recognition of viral nucleic acids and regulation of type I IFN expression]. (2006) (2)
- SS4-2 Virus-infection or 5’ppp-RNA activates antiviral signal through redistribution of IPS-1 mediated by MFN1 (2010) (1)
- Two Step Activation of the Interleukin-2 Autocrine Loop May be Involved in ATL Development (1987) (1)
- drug-resistant avian H5N1 as well as 1918 and 2009 pandemic influenza virus replication (2010) (1)
- RIG-I and PKR, but not stress granules, mediate the pro-inflammatory response to Yellow fever virus (2020) (1)
- PKR and TLR3 trigger distinct signals that coordinate the induction of antiviral apoptosis (2022) (1)
- Nucleotide sequence of the mouse interferon-beta gene. (1989) (1)
- Correction: Co-ordinated Role of TLR3, RIG-I and MDA5 in the Innate Response to Rhinovirus in Bronchial Epithelium (2012) (1)
- Solution structure of LGP2 CTD (2009) (1)
- Regulation of the interleukin-2 system and T cell neoplasm. (1988) (1)
- The Nonstructural Protein NSs of Severe Fever with Thrombocytopenia Syndrome Virus Causes a Cytokine Storm through the Hyperactivation of NF-κB (2020) (1)
- Virus-infection in cochlear supporting cells induces audiosensory receptor hair cell death by TRAIL-induced necroptosis (2021) (1)
- Impaired antiviral stress granule and IFN-β enhanceosome formation enhances susceptibility to influenza infection in COPD epithelium (2016) (1)
- Induction and Evasion of Innate Immunity by hepatitis C virus (2006) (1)
- Shinobu, N. et al. Involvement of TIRAP/MAL in signaling for the activation of interferon regulatory factor 3 by lipopolysaccharide. FEBS Lett. 571, 251-256 (2002) (1)
- ID: 255: Autoimmunity due to constitutive activation of cytoplasmic viral RNA sensors (2015) (1)
- The Amino Acid at Position 95 in the Matrix Protein of Rabies Virus Is Involved in Antiviral Stress Granule Formation in Infected Cells (2022) (1)
- PP2-185 Mitochondrial dynamics and innate antiviral responses regulated by RIG-I-like receptorMitochondrial dynamics and innate antiviral responses regulated by RIG-I-like receptor (2009) (0)
- S-19 : Epigenetic regulation of interferon response (2014) (0)
- Aberrant Activation of RIG-I–Like Receptors and Autoimmune Diseases (2016) (0)
- Non-canonical role of E3 ligase RIPLET in innate immunity as a co-receptor for RIG-I (2018) (0)
- Influenza A virus NS1 optimises virus infectivity by enhancing genome packaging in a dsRNA-binding dependent manner (2020) (0)
- ID: 70: A novel function of human Pumilio proteins in antiviral innate immunity (2015) (0)
- Correction: A Plant-Derived Nucleic Acid Reconciles Type I IFN and a Pyroptotic-like Event in Immunity against Respiratory Viruses (2018) (0)
- Title Recognition of viruses in the cytoplasm by RLRs and other helicases--how conformational changes, mitochondrial dynamics and ubiquitination control innate immune responses (2018) (0)
- SENSORS FOR REPLICATING VIRUSES AND INNATE IMMUNITY (2007) (0)
- Title Leader-Containing Uncapped Viral Transcript Activates RIG-Iin Antiviral Stress Granules ( Correction ) (2016) (0)
- Sensors for Replicating Viruses and Innate Immunity [Emerging Theories of Host Defense. The 10th Meeting Hirosaki International Forum of Medical Science. Communication Center Hirosaki University School of Medicine. Hirosaki on November 21-22, 2006] (2007) (0)
- [Mechanism of virus-induced expression of type I interferon genes]. (2007) (0)
- Activation of an antiviral program through the cytoplasmic recognition of non-self RNA patterns by RLR (2009) (0)
- A sense for sensors of danger (2020) (0)
- APC Lipopolysaccharide-Induced Activation of IL-1 R-Associated Kinase 4 Is Required for and (2003) (0)
- Correction: Critical Role of an Antiviral Stress Granule Containing RIG-I and PKR in Viral Detection and Innate Immunity (2013) (0)
- 3-1-4 Production of antiviral compounds against encephalomyocarditis virus (EMCV) from woody biomass by microwave reaction (2019) (0)
- Instructions for use Title Solution Structures of Cytosolic RNA Sensor MDA 5 and LGP 2 C-terminal Domains : Identification ofthe RNA Recognition Loop in RIG-ILIKE Receptors (2017) (0)
- phosphorylation-dependent manner. interacts with NF-kappa B p50 and p52 in a kappa B-like molecule that preferentially The bcl-3 proto-oncogene encodes a nuclear I (2014) (0)
- Molecular Biology of Interleukin-2 and Its Receptor: The Current Status (1986) (0)
- Solution structure of MDA5 CTD (2009) (0)
- Double-Stranded RNA Induces Mortality in an MDA5-Mediated Type I Interferonopathy Model. (2022) (0)
- Antiviral Action of TNF in Human Fibroblasts Requires the Presence of Subeffective Concentrations of Classical Interferon‐β a (1989) (0)
- [Regulatory mechanism of gene expression in interferon system]. (1990) (0)
- PL-7 Mechanism of foreign RNA recognition in the cytoplasm (2008) (0)
- 81: Critical role of PKR in antiviral stress granule and IFN-β enhanceosome formation, and is impaired in chronic obstructive pulmonary disease (2014) (0)
- Title Functional Characterization of Domains of IPS-1 Using anInducible Oligomerization System (2017) (0)
- Cochlear supporting cells function as macrophage-like cells and protect audiosensory receptor hair cells from pathogens (2020) (0)
- Analysis of intracellular localization of viral RNA sensor, RLR (2011) (0)
- 192: The functional analysis of RIG-I-inducible microRNA (2013) (0)
- Spatio-temporal characterization of the antiviral activity of the XRN1-DCP1/2 aggregation against cytoplasmic RNA viruses to prevent cell death (2020) (0)
- Mechanisms of length-dependent recognition of viral double-stranded RNA by RIG-I. (2023) (0)
- Analysisi of effects of aggregated proteins on a cell (1998) (0)
- Lipopolysaccharide-Inducible Genes the Expression of a Subset of Activation of IFN-Regulatory Factor 3 and MyD 88-Independent Pathway and Results in Lipopolysaccharide Stimulates the and Shizuo (2001) (0)
- Solution structure of RIG-I C-terminal domain (2008) (0)
- Melatonin suppresses the antiviral immune response to EMCV infection through intracellular ATP deprivation caused by mitochondrial fragmentation (2022) (0)
- Pathways in Type I IFN Induction Both the TLR3 and the Cytoplasmic NAK-Associated Protein 1 Participates in (2006) (0)
- Preface to Signature Diseases Special Issue. (2017) (0)
- This information is current as Immunity against Respiratory Viruses Type I IFN and a Pyroptotic-like Event in A Plant-Derived Nucleic Acid Reconciles (2017) (0)
- Double-Stranded RNA Induces Mortality in an MDA5-Mediated Type I Interferonopathy Model. (2022) (0)
- Changes of enzymatic activities concern glycolysis and amino acid metabolism in the host liver of the rats bearing tumors (1966) (0)
- Attenuation of regulatory T cell function by type I IFN signaling in an MDA5 gain-of-function mutant mouse model. (2022) (0)
- Is Caused by IFIH1 Mutations (2020) (0)
- Antiviral activity of human OASL is mediated by mimicking ubiquitin chains to activate RIG-I pathway (INM6P.421) (2014) (0)
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What Schools Are Affiliated With Takashi Fujita?
Takashi Fujita is affiliated with the following schools:
