Takashi Kadowaki
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Takashi Kadowaki's Degrees
- PhD Biochemistry University of Tokyo
- Doctorate Medicine University of Tokyo
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(Suggest an Edit or Addition)Takashi Kadowaki's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity (2001) (4863)
- Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase (2002) (4166)
- Cloning of adiponectin receptors that mediate antidiabetic metabolic effects (2003) (3033)
- Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome. (2006) (2634)
- Adiponectin and adiponectin receptors. (2005) (2563)
- CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity (2009) (1980)
- Report of the Committee on the Classification and Diagnostic Criteria of Diabetes Mellitus (2010) (1938)
- Diabetes in Asia: epidemiology, risk factors, and pathophysiology. (2009) (1869)
- Disruption of Adiponectin Causes Insulin Resistance and Neointimal Formation* (2002) (1382)
- PPARγ Mediates High-Fat Diet–Induced Adipocyte Hypertrophy and Insulin Resistance (1999) (1243)
- Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions (2007) (1239)
- Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1 (1994) (1071)
- Impaired Multimerization of Human Adiponectin Mutants Associated with Diabetes (2003) (994)
- Troglitazone increases the number of small adipocytes without the change of white adipose tissue mass in obese Zucker rats. (1998) (985)
- Growth retardation and increased apoptosis in mice with homozygous disruption of the Akt1 gene. (2001) (962)
- International Union of Pharmacology. LXI. Peroxisome Proliferator-Activated Receptors (2006) (946)
- Globular Adiponectin Protected ob/ob Mice from Diabetes and ApoE-deficient Mice from Atherosclerosis* (2003) (945)
- Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility (2014) (933)
- Overexpression of Monocyte Chemoattractant Protein-1 in Adipose Tissues Causes Macrophage Recruitment and Insulin Resistance* (2006) (867)
- PPARgamma insufficiency enhances osteogenesis through osteoblast formation from bone marrow progenitors. (2004) (834)
- Adiponectin and AdipoR1 regulate PGC-1α and mitochondria by Ca2+ and AMPK/SIRT1 (2010) (821)
- Adiponectin stimulates AMP-activated protein kinase in the hypothalamus and increases food intake. (2007) (776)
- Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus (2008) (739)
- SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations (2008) (717)
- Genetic variation in the gene encoding adiponectin is associated with an increased risk of type 2 diabetes in the Japanese population. (2002) (714)
- Cardiovascular Disease and Risk Factors in Asia: A Selected Review (2008) (627)
- PI3K-mediated negative feedback regulation of IL-12 production in DCs (2002) (609)
- The Mechanisms by Which Both Heterozygous Peroxisome Proliferator-activated Receptor γ (PPARγ) Deficiency and PPARγ Agonist Improve Insulin Resistance* (2001) (593)
- Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians (2011) (581)
- Report of the Committee on the classification and diagnostic criteria of diabetes mellitus. (2002) (566)
- A subtype of diabetes mellitus associated with a mutation of mitochondrial DNA. (1994) (560)
- A simple method to estimate populational 24-h urinary sodium and potassium excretion using a casual urine specimen (2002) (539)
- A small-molecule AdipoR agonist for type 2 diabetes and short life in obesity (2013) (539)
- PPAR gamma mediates high-fat diet-induced adipocyte hypertrophy and insulin resistance. (1999) (536)
- Disruption of insulin receptor substrate 2 causes type 2 diabetes because of liver insulin resistance and lack of compensatory beta-cell hyperplasia. (2000) (532)
- Single-nucleotide polymorphism haplotypes in the both proximal promoter and exon 3 of the APM1 gene modulate adipocyte-secreted adiponectin hormone levels and contribute to the genetic risk for type 2 diabetes in French Caucasians. (2002) (511)
- Xid-like immunodeficiency in mice with disruption of the p85alpha subunit of phosphoinositide 3-kinase. (1999) (510)
- The Residual Risk Reduction Initiative: a call to action to reduce residual vascular risk in patients with dyslipidemia. (2008) (473)
- A liver-derived secretory protein, selenoprotein P, causes insulin resistance. (2010) (468)
- Role of NADH shuttle system in glucose-induced activation of mitochondrial metabolism and insulin secretion. (1999) (456)
- Adipogenesis in Obesity Requires Close Interplay Between Differentiating Adipocytes, Stromal Cells, and Blood Vessels (2007) (453)
- Saturated fatty acid and TLR signaling link β cell dysfunction and islet inflammation. (2012) (445)
- Krüppel-like transcription factor KLF5 is a key regulator of adipocyte differentiation. (2005) (431)
- Increased insulin sensitivity and hypoglycaemia in mice lacking the p85α subunit of phosphoinositide 3–kinase (1999) (428)
- Krüppel-like zinc-finger transcription factor KLF5/BTEB2 is a target for angiotensin II signaling and an essential regulator of cardiovascular remodeling (2002) (395)
- Impaired insulin signaling in endothelial cells reduces insulin-induced glucose uptake by skeletal muscle. (2011) (386)
- Insulin/Foxo1 Pathway Regulates Expression Levels of Adiponectin Receptors and Adiponectin Sensitivity* (2004) (384)
- Potential Role of Protein Kinase B in Insulin-induced Glucose Transport, Glycogen Synthesis, and Protein Synthesis* (1998) (380)
- Peroxisome Proliferator–Activated Receptor (PPAR)α Activation Increases Adiponectin Receptors and Reduces Obesity-Related Inflammation in Adipose Tissue: Comparison of Activation of PPARα, PPARγ, and Their Combination (2005) (369)
- Role of Krüppel-like Factor 15 (KLF15) in Transcriptional Regulation of Adipogenesis* (2005) (336)
- Adiponectin receptor as a key player in healthy longevity and obesity-related diseases. (2013) (331)
- Glucokinase and IRS-2 are required for compensatory beta cell hyperplasia in response to high-fat diet-induced insulin resistance. (2007) (329)
- Pioglitazone Ameliorates Insulin Resistance and Diabetes by Both Adiponectin-dependent and -independent Pathways* (2006) (322)
- Physiological and pathophysiological roles of adiponectin and adiponectin receptors in the integrated regulation of metabolic and cardiovascular diseases (2008) (319)
- Generation of globular fragment of adiponectin by leukocyte elastase secreted by monocytic cell line THP-1. (2005) (318)
- Mechanical loading activates mitogen-activated protein kinase and S6 peptide kinase in cultured rat cardiac myocytes. (1993) (313)
- Tyrosine phosphorylation of the EGF receptor by the kinase Jak2 is induced by growth hormone (1997) (307)
- Two mammalian heat shock proteins, HSP90 and HSP100, are actin-binding proteins. (1986) (306)
- Regulation of bone formation by adiponectin through autocrine/paracrine and endocrine pathways (2006) (295)
- Two mutant alleles of the insulin receptor gene in a patient with extreme insulin resistance. (1988) (289)
- Cytokines suppress adipogenesis and PPAR-γ function through the TAK1/TAB1/NIK cascade (2003) (287)
- Insulin signalling and insulin actions in the muscles and livers of insulin-resistant, insulin receptor substrate 1-deficient mice (1996) (286)
- Inhibition of RXR and PPARgamma ameliorates diet-induced obesity and type 2 diabetes. (2001) (284)
- The mechanisms by which both heterozygous peroxisome proliferator-activated receptor gamma (PPARgamma) deficiency and PPARgamma agonist improve insulin resistance. (2001) (282)
- The physiological and pathophysiological role of adiponectin and adiponectin receptors in the peripheral tissues and CNS (2008) (277)
- Adiponectin receptors: a review of their structure, function and how they work. (2014) (275)
- Matrix/Integrin Interaction Activates the Mitogen-activated Protein Kinase, p44 and p42(*) (1995) (266)
- A novel insulin sensitizer acts as a coligand for peroxisome proliferator-activated receptor-alpha (PPAR-alpha) and PPAR-gamma: effect of PPAR-alpha activation on abnormal lipid metabolism in liver of Zucker fatty rats. (1998) (264)
- Insulin receptor substrate-1 in osteoblast is indispensable for maintaining bone turnover. (2000) (264)
- The Pro12Ala Polymorphism in PPAR γ2 May Confer Resistance to Type 2 Diabetes (2000) (264)
- A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B (2010) (261)
- The Residual Risk Reduction Initiative: a call to action to reduce residual vascular risk in dyslipidaemic patients (2008) (261)
- Fusion Pore Dynamics and Insulin Granule Exocytosis in the Pancreatic Islet (2002) (260)
- In vivo imaging in mice reveals local cell dynamics and inflammation in obese adipose tissue. (2008) (259)
- Angiotensin II receptor antagonist TCV-116 induces regression of hypertensive left ventricular hypertrophy in vivo and inhibits the intracellular signaling pathway of stretch-mediated cardiomyocyte hypertrophy in vitro. (1994) (255)
- Adiponectin enhances insulin sensitivity by increasing hepatic IRS-2 expression via a macrophage-derived IL-6-dependent pathway. (2011) (255)
- The Pro12 -->Ala substitution in PPAR-gamma is associated with resistance to development of diabetes in the general population: possible involvement in impairment of insulin secretion in individuals with type 2 diabetes. (2001) (253)
- Oral semaglutide versus subcutaneous liraglutide and placebo in type 2 diabetes (PIONEER 4): a randomised, double-blind, phase 3a trial (2019) (251)
- Genome-wide search for type 2 diabetes in Japanese affected sib-pairs confirms susceptibility genes on 3q, 15q, and 20q and identifies two new candidate Loci on 7p and 11p. (2002) (249)
- Insights into insulin resistance and type 2 diabetes from knockout mouse models. (2000) (249)
- A genetic variation in the PGC-1 gene could confer insulin resistance and susceptibility to Type II diabetes (2002) (242)
- Peroxisome Proliferator-Activated Receptor γ Plays a Critical Role in Inhibition of Cardiac Hypertrophy In Vitro and In Vivo (2002) (241)
- Insulin receptor substrate 2 plays a crucial role in beta cells and the hypothalamus. (2004) (240)
- Hypertension, hypertriglyceridemia, and impaired endothelium-dependent vascular relaxation in mice lacking insulin receptor substrate-1. (1998) (238)
- Marine-derived n-3 fatty acids and atherosclerosis in Japanese, Japanese-American, and white men: a cross-sectional study. (2008) (231)
- Co-ordinate activation of lipogenic enzymes in hepatocellular carcinoma. (2005) (229)
- A cross-population atlas of genetic associations for 220 human phenotypes (2021) (229)
- Akt1 in Osteoblasts and Osteoclasts Controls Bone Remodeling (2007) (225)
- Decreased autophosphorylation of the insulin receptor-kinase in streptozotocin-diabetic rats. (1984) (224)
- Mutations in Insulin-Receptor Gene in Insulin-Resistant Patients (1990) (222)
- Role of altered renal lipid metabolism in the development of renal injury induced by a high-fat diet. (2007) (222)
- A comparative study of the binding modes of recently launched dipeptidyl peptidase IV inhibitors in the active site. (2013) (220)
- Endogenous PPARγ mediates anti-inflammatory activity in murine ischemia-reperfusion injury (2001) (218)
- Dynamic functional relay between insulin receptor substrate 1 and 2 in hepatic insulin signaling during fasting and feeding. (2008) (216)
- Variations in the HHEX gene are associated with increased risk of type 2 diabetes in the Japanese population (2007) (213)
- Selective loss of gastrointestinal mast cells and impaired immunity in PI3K-deficient mice (2002) (210)
- Neuronal IGF‐1 resistance reduces Aβ accumulation and protects against premature death in a model of Alzheimer's disease (2009) (207)
- Peroxisome proliferator-activated receptor gamma ligands suppress colon carcinogenesis induced by azoxymethane in mice. (2003) (205)
- Association Between Plasma Triglycerides and High-Density Lipoprotein Cholesterol and Microvascular Kidney Disease and Retinopathy in Type 2 Diabetes Mellitus: A Global Case–Control Study in 13 Countries (2013) (203)
- Molecular Mechanism of Insulin Resistance and Obesity (2003) (202)
- Osmotin is a homolog of mammalian adiponectin and controls apoptosis in yeast through a homolog of mammalian adiponectin receptor. (2005) (200)
- Essential Role of Insulin Receptor Substrate 1 (IRS-1) and IRS-2 in Adipocyte Differentiation (2001) (198)
- Angiopoietin-related growth factor antagonizes obesity and insulin resistance (2005) (198)
- Adipose Natural Regulatory B Cells Negatively Control Adipose Tissue Inflammation. (2013) (196)
- Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases (2020) (191)
- A novel PPAR gamma gene therapy to control inflammation associated with inflammatory bowel disease in a murine model. (2003) (189)
- Growth Hormone and Prolactin Stimulate Tyrosine Phosphorylation of Insulin Receptor Substrate-1, -2, and -3, Their Association with p85 Phosphatidylinositol 3-Kinase (PI3-kinase), and Concomitantly PI3-kinase Activation via JAK2 Kinase* (1998) (189)
- Identification of type 2 diabetes loci in 433,540 East Asian individuals (2019) (188)
- Cigarette Smoking as a Risk Factor for Stroke Death in Japan NIPPON DATA80 (2004) (188)
- Effect of an intensified multifactorial intervention on cardiovascular outcomes and mortality in type 2 diabetes (J-DOIT3): an open-label, randomised controlled trial. (2017) (186)
- Acetic acid activates hepatic AMPK and reduces hyperglycemia in diabetic KK-A(y) mice. (2006) (184)
- Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease (2017) (179)
- Cognitive impairment as a strong predictor of incident disability in specific ADL-IADL tasks among community-dwelling elders: the Azuchi Study. (2005) (179)
- Five mutant alleles of the insulin receptor gene in patients with genetic forms of insulin resistance. (1990) (178)
- Adiponectin suppresses colorectal carcinogenesis under the high-fat diet condition (2008) (178)
- Peroxisome Proliferator-Activated Receptor Gamma Agonist Ligands Stimulate a Th2 Cytokine Response and Prevent Acute Colitis (2002) (176)
- Pulsatile stretch activates mitogen-activated protein kinase (MAPK) family members and focal adhesion kinase (p125(FAK)) in cultured rat cardiac myocytes. (1999) (173)
- Risk factors for worsening to diabetes in subjects with impaired glucose tolerance (2004) (172)
- Genome-Wide Association Study Identifies a Novel Locus Contributing to Type 2 Diabetes Susceptibility in Sikhs of Punjabi Origin From India (2013) (168)
- Involvement of p85 in p53-dependent apoptotic response to oxidative stress (1998) (167)
- IL-1α induces thrombopoiesis through megakaryocyte rupture in response to acute platelet needs (2015) (167)
- Adiponectin suppresses hepatic SREBP1c expression in an AdipoR1/LKB1/AMPK dependent pathway. (2009) (166)
- Crystal structures of the human adiponectin receptors (2015) (165)
- Both Gs and Gi Proteins Are Critically Involved in Isoproterenol-induced Cardiomyocyte Hypertrophy* (1999) (162)
- The relationship between serum total cholesterol and all-cause or cause-specific mortality in a 17.3-year study of a Japanese cohort. (2007) (160)
- A novel ELISA system for selective measurement of human adiponectin multimers by using proteases. (2006) (160)
- Biphasic activation of two mitogen-activated protein kinases during the cell cycle in mammalian cells. (1992) (158)
- Alcohol consumption and other risk factors for self‐reported diabetes among middle‐aged Japanese: a population‐based prospective study in the JPHC study cohort I (2005) (158)
- DialBetics: A Novel Smartphone-based Self-management Support System for Type 2 Diabetes Patients. (2014) (158)
- Residual macrovascular risk in 2013: what have we learned? (2014) (157)
- Cytokines suppress adipogenesis and PPAR-gamma function through the TAK1/TAB1/NIK cascade. (2003) (156)
- PI3K and Btk differentially regulate B cell antigen receptor-mediated signal transduction (2003) (155)
- Expression of adiponectin receptors and its possible implication in the human endometrium. (2006) (155)
- A genetic variation of the transcription factor 7-like 2 gene is associated with risk of type 2 diabetes in the Japanese population (2007) (153)
- Tyrosine phosphorylation of common and specific sets of cellular proteins rapidly induced by insulin, insulin-like growth factor I, and epidermal growth factor in an intact cell. (1987) (152)
- Trial of Insulinlike Growth Factor I Therapy for Patients With Extreme Insulin Resistance Syndromes (1993) (152)
- Post-priming actions of ATP on Ca2+-dependent exocytosis in pancreatic beta cells. (1999) (152)
- Selective purification and characterization of adiponectin multimer species from human plasma. (2007) (151)
- Randomized controlled trial of sour milk on blood pressure in borderline hypertensive men. (2004) (150)
- Increased insulin sensitivity despite lipodystrophy in Crebbp heterozygous mice (2002) (149)
- Genome-wide association study identifies three novel loci for type 2 diabetes. (2014) (149)
- Rho family small G proteins play critical roles in mechanical stress-induced hypertrophic responses in cardiac myocytes. (1999) (149)
- Peroxisome Proliferator-activated Receptor γ-mediated Regulation of Neural Stem Cell Proliferation and Differentiation* (2006) (146)
- Evi1 is essential for hematopoietic stem cell self-renewal, and its expression marks hematopoietic cells with long-term multilineage repopulating activity (2011) (146)
- Dual roles of adiponectin/Acrp30 in vivo as an anti-diabetic and anti-atherogenic adipokine. (2003) (145)
- Less subclinical atherosclerosis in Japanese men in Japan than in White men in the United States in the post-World War II birth cohort. (2007) (145)
- Usefulness of measuring both body mass index and waist circumference for the estimation of visceral adiposity and related cardiometabolic risk profile (from the INSPIRE ME IAA study). (2015) (144)
- Effect of the Pro12Ala variant of the human peroxisome proliferator-activated receptor gamma 2 gene on adiposity, fat distribution, and insulin sensitivity in Japanese men. (1998) (140)
- Development of non-insulin-dependent diabetes mellitus in the double knockout mice with disruption of insulin receptor substrate-1 and beta cell glucokinase genes. Genetic reconstitution of diabetes as a polygenic disease. (1997) (140)
- Insulin receptor substrate-2 maintains predominance of anabolic function over catabolic function of osteoblasts (2002) (139)
- A nonsense mutation causing decreased levels of insulin receptor mRNA: detection by a simplified technique for direct sequencing of genomic DNA amplified by the polymerase chain reaction. (1990) (139)
- Increased Expression of the Sterol Regulatory Element-binding Protein-1 Gene in Insulin Receptor Substrate-2−/−Mouse Liver* (2001) (138)
- Transplantation of adipose tissue lacking leptin is unable to reverse the metabolic abnormalities associated with lipoatrophy. (2002) (137)
- Expression-based genome-wide association study links the receptor CD44 in adipose tissue with type 2 diabetes (2012) (137)
- Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes (2016) (136)
- What cause of mortality can we predict by cholesterol screening in the Japanese general population? (2003) (136)
- Adiponectin inhibits the growth and peritoneal metastasis of gastric cancer through its specific membrane receptors AdipoR1 and AdipoR2 (2007) (136)
- Hypoadiponectinaemia and high risk of type 2 diabetes are associated with adiponectin-encoding (ACDC) gene promoter variants in morbid obesity: evidence for a role of ACDC in diabesity (2005) (135)
- Peroxisome proliferator-activated receptor gamma plays a critical role in inhibition of cardiac hypertrophy in vitro and in vivo. (2002) (134)
- Cell Type–Specific Angiotensin II–Evoked Signal Transduction Pathways (1998) (134)
- Annexin II Is a Novel Player in Insulin Signal Transduction (1996) (132)
- Adiponectin induces insulin secretion in vitro and in vivo at a low glucose concentration (2008) (130)
- Peroxisome proliferator-activated receptor-gamma haploinsufficiency enhances B cell proliferative responses and exacerbates experimentally induced arthritis. (2001) (129)
- Hypoxia and hypoxia/reoxygenation activate Raf-1, mitogen-activated protein kinase kinase, mitogen-activated protein kinases, and S6 kinase in cultured rat cardiac myocytes. (1996) (126)
- Enhancement of the Aquaporin Adipose Gene Expression by a Peroxisome Proliferator-activated Receptor γ* (2001) (126)
- SUMOylation of Krüppel-like transcription factor 5 acts as a molecular switch in transcriptional programs of lipid metabolism involving PPAR-δ (2008) (125)
- Macrophage-derived AIM is endocytosed into adipocytes and decreases lipid droplets via inhibition of fatty acid synthase activity. (2010) (124)
- Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population (2019) (124)
- Polyunsaturated Fatty Acids Selectively Suppress Sterol Regulatory Element-binding Protein-1 through Proteolytic Processing and Autoloop Regulatory Circuit* (2010) (124)
- Hypoxia and hypoxia/reoxygenation activate p65PAK, p38 mitogen-activated protein kinase (MAPK), and stress-activated protein kinase (SAPK) in cultured rat cardiac myocytes. (1997) (124)
- p53 Involvement in the Pathogenesis of Fatty Liver Disease* (2004) (124)
- Adiponectin regulates psoriasiform skin inflammation by suppressing IL-17 production from γδ-T cells (2015) (123)
- Adiponectin Regulates Cutaneous Wound Healing by Promoting Keratinocyte Proliferation and Migration via the ERK Signaling Pathway (2012) (122)
- Myeloid lineage cell-restricted insulin resistance protects apolipoproteinE-deficient mice against atherosclerosis. (2006) (121)
- PPAR gamma ligands inhibit nitrotyrosine formation and inflammatory mediator expressions in adjuvant-induced rheumatoid arthritis mice. (2002) (121)
- Psychological factors, coffee and risk of diabetes mellitus among middle-aged Japanese: a population-based prospective study in the JPHC study cohort. (2009) (119)
- A mutation of the b3-adrenergic receptor is associated with visceral obesity but decreased serum triglyceride (1997) (118)
- Human diabetes associated with a mutation in the tyrosine kinase domain of the insulin receptor. (1989) (118)
- Global Mapping of Cell Type–Specific Open Chromatin by FAIRE-seq Reveals the Regulatory Role of the NFI Family in Adipocyte Differentiation (2011) (118)
- Roles of ATP-sensitive K+ channels as metabolic sensors: studies of Kir6.x null mice. (2004) (116)
- Body Composition Is the Main Determinant for the Difference in Type 2 Diabetes Pathophysiology Between Japanese and Caucasians (2014) (116)
- The inverse relationship between serum high-density lipoprotein cholesterol level and all-cause mortality in a 9.6-year follow-up study in the Japanese general population. (2006) (115)
- Tofogliflozin Improves Insulin Resistance in Skeletal Muscle and Accelerates Lipolysis in Adipose Tissue in Male Mice. (2016) (115)
- Insulin-like growth factors, insulin, and epidermal growth factor cause rapid cytoskeletal reorganization in KB cells. Clarification of the roles of type I insulin-like growth factor receptors and insulin receptors. (1986) (114)
- Glycemic control, mortality, and hypoglycemia in critically ill patients: a systematic review and network meta-analysis of randomized controlled trials (2016) (113)
- Maternally inherited diabetes and deafness: a new diabetes subtype (1996) (113)
- Japanese men have larger areas of visceral adipose tissue than Caucasian men in the same levels of waist circumference in a population-based study (2012) (113)
- Resting heart rate and cause-specific death in a 16.5-year cohort study of the Japanese general population. (2004) (112)
- Peroxisome proliferator-activated receptor (PPAR)alpha activation increases adiponectin receptors and reduces obesity-related inflammation in adipose tissue: comparison of activation of PPARalpha, PPARgamma, and their combination. (2005) (112)
- Constitutive Tyrosine Phosphorylation of ErbB-2 via Jak2 by Autocrine Secretion of Prolactin in Human Breast Cancer* (2000) (111)
- SREBP-1-independent regulation of lipogenic gene expression in adipocytes Published, JLR Papers in Press, April 24, 2007. (2007) (109)
- Imbalanced Insulin Actions in Obesity and Type 2 Diabetes: Key Mouse Models of Insulin Signaling Pathway. (2017) (107)
- Use of polymerase chain reaction catalyzed by Taq DNA polymerase for site-specific mutagenesis. (1989) (106)
- Signal transduction pathways from insulin receptors to Ras. Analysis by mutant insulin receptors. (1994) (104)
- Ethidium Bromide-induced Inhibition of Mitochondrial Gene Transcription Suppresses Glucose-stimulated Insulin Release in the Mouse Pancreatic β-Cell Line βHC9* (1998) (104)
- The Pro12Ala polymorphism in PPAR gamma2 may confer resistance to type 2 diabetes. (2000) (104)
- Identification of Neutral Cholesterol Ester Hydrolase, a Key Enzyme Removing Cholesterol from Macrophages* (2008) (104)
- Endogenous PPAR gamma mediates anti-inflammatory activity in murine ischemia-reperfusion injury. (2001) (104)
- Ablation of neutral cholesterol ester hydrolase 1 accelerates atherosclerosis. (2009) (104)
- A single-nucleotide polymorphism in ANK1 is associated with susceptibility to type 2 diabetes in Japanese populations. (2012) (103)
- Role of suppressors of cytokine signaling SOCS-1 and SOCS-3 in hepatic steatosis and the metabolic syndrome. (2005) (103)
- Upstream Mechanisms of Glycogen Synthase Activation by Insulin and Insulin-like Growth Factor-I (1995) (101)
- Role of Insulin Receptor Substrate-1 and pp60 in the Regulation of Insulin-induced Glucose Transport and GLUT4 Translocation in Primary Adipocytes* (1997) (100)
- Genome-Wide Search for Type 2 Diabetes in Japanese Affected Sib-Pairs Confirms Susceptibility Genes on 3 q , 15 q , and 20 q and Identifies Two New Candidate Loci on 7 p and 11 p (2002) (100)
- Efficacy and safety of sitagliptin monotherapy compared with voglibose in Japanese patients with type 2 diabetes: a randomized, double‐blind trial (2010) (99)
- Daytime Napping and the Risk of Cardiovascular Disease and All-Cause Mortality: A Prospective Study and Dose-Response Meta-Analysis. (2015) (98)
- Genome-wide association study in a Chinese population identifies a susceptibility locus for type 2 diabetes at 7q32 near PAX4 (2013) (97)
- Class IA phosphatidylinositol 3-kinase in pancreatic β cells controls insulin secretion by multiple mechanisms. (2010) (97)
- Lack of Insulin Receptor Substrate‐2 Causes Progressive Neointima Formation in Response to Vessel Injury (2003) (96)
- Variations of plantar thermographic patterns in normal controls and non-ulcer diabetic patients: novel classification using angiosome concept. (2011) (96)
- Egg consumption, serum cholesterol, and cause-specific and all-cause mortality: the National Integrated Project for Prospective Observation of Non-communicable Disease and Its Trends in the Aged, 1980 (NIPPON DATA80). (2004) (96)
- Multiple Exocytotic Pathways in Pancreatic β Cells (1997) (96)
- Association between fish consumption and all-cause and cause-specific mortality in Japan: NIPPON DATA80, 1980-99. (2005) (96)
- Pioglitazone reduces islet triglyceride content and restores impaired glucose-stimulated insulin secretion in heterozygous peroxisome proliferator-activated receptor-gamma-deficient mice on a high-fat diet. (2004) (94)
- Association Studies of Variants in the Genes Involved in Pancreatic β-Cell Function in Type 2 Diabetes in Japanese Subjects (2006) (93)
- Adiponectin knockout mice on high fat diet develop fibrosing steatohepatitis (2009) (93)
- The RNA Methyltransferase Complex of WTAP, METTL3, and METTL14 Regulates Mitotic Clonal Expansion in Adipogenesis (2018) (92)
- Association of TCF7L2 polymorphisms with susceptibility to type 2 diabetes in 4,087 Japanese subjects (2008) (92)
- Functional phenotype of phosphoinositide 3-kinase p85alpha-null platelets characterized by an impaired response to GP VI stimulation. (2003) (92)
- Evidence for direct binding of fatty acids and eicosanoids to human peroxisome proliferators-activated receptor alpha. (1999) (91)
- Lower Levels of Serum Albumin and Total Cholesterol Associated with Decline in Activities of Daily Living and Excess Mortality in a 12‐Year Cohort Study of Elderly Japanese (2008) (89)
- Nuclear receptors as targets for drug development: molecular mechanisms for regulation of obesity and insulin resistance by peroxisome proliferator-activated receptor gamma, CREB-binding protein, and adiponectin. (2005) (89)
- Effects of once‐daily teneligliptin on 24‐h blood glucose control and safety in Japanese patients with type 2 diabetes mellitus: a 4‐week, randomized, double‐blind, placebo‐controlled trial (2012) (88)
- Genetic Risk Score Constructed Using 14 Susceptibility Alleles for Type 2 Diabetes Is Associated With the Early Onset of Diabetes and May Predict the Future Requirement of Insulin Injections Among Japanese Individuals (2012) (88)
- Chronic kidney disease is a risk factor for cardiovascular death in a community-based population in Japan: NIPPON DATA90. (2006) (88)
- Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation (2020) (88)
- Japanese men have larger areas of visceral adipose tissue than Caucasian men in the same levels of waist circumference in a population-based study (2006) (88)
- Feedback regulation of mitogen-activated protein kinase kinase kinase activity of c-Raf-1 by insulin and phorbol ester stimulation. (1994) (88)
- Phosphatidylinositol 3-Kinase and NF-κB/Rel Are at the Divergence of CD40-Mediated Proliferation and Survival Pathways (2000) (87)
- Mutagenesis of lysine 460 in the human insulin receptor. Effects upon receptor recycling and cooperative interactions among binding sites. (1990) (87)
- Clinical features of diabetes mellitus with the mitochondrial DNA 3243 (A-G) mutation in Japanese: maternal inheritance and mitochondria-related complications. (2003) (87)
- Identification of a 190-kDa Protein as a Novel Substrate for the Insulin Receptor Kinase Functionally Similar to Insulin Receptor Substrate-1 (*) (1995) (87)
- Age-specific effects of systolic and diastolic blood pressures on mortality due to cardiovascular diseases among Japanese men (NIPPON DATA80*) (2006) (87)
- Empagliflozin in Patients with Chronic Kidney Disease (2022) (86)
- Mechanical Stretch Induces Hypertrophic Responses in Cardiac Myocytes of Angiotensin II Type 1a Receptor Knockout Mice* (1998) (86)
- Nitration of PPARγ inhibits ligand‐dependent translocation into the nucleus in a macrophage‐like cell line, RAW 264 (2002) (86)
- Vascular endothelial growth factor induces activation and subcellular translocation of focal adhesion kinase (p125FAK) in cultured rat cardiac myocytes. (1999) (85)
- Site-directed mutagenesis of the juxtamembrane domain of the human insulin receptor. (1993) (85)
- The Critical Role of Neutral Cholesterol Ester Hydrolase 1 in Cholesterol Removal From Human Macrophages (2010) (85)
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- Diabetes mellitus defined by hemoglobin A1c value: Risk characterization for incidence among Japanese subjects in the JPHC Diabetes Study (2011) (2)
- Maturity-onset diabetes of the young resulting from a novel mutation in the HNF-4alpha gene. (2002) (2)
- [Diabetes and osteoporosis]. (2004) (2)
- [PPARgamma antagonist as a potential drug for the treatment of obesity and diabetes]. (2010) (2)
- Combined treatment with low-dose pioglitazone and beraprost sodium improves glucose intolerance without causing body weight gain (2013) (2)
- Effects of beraprost sodium, an oral prostacyclin analog, on insulin resistance in patients with type 2 diabetes (2015) (2)
- Metabolic syndrome : carcinogenesis and prevention : Extended abstracts for the 39th International Symposium of the Princess Takamatsu Cancer Research Fund : November 11-13, 2008 Tokyo, Japan (2009) (2)
- Familial disorder with increased number of insulin receptors: a new category of insulin receptor abnormality. (1986) (2)
- Milk, Dairy Products and Metabolic Syndrome : A Cross-sectional Study of Japanese (2010) (2)
- Association between polymorphism of the AGTR1 and cardiovascular events in a Japanese general sample (The Shigaraki Study). (2009) (2)
- Associations between diabetes duration and self-stigma development in Japanese people with type 2 diabetes: a secondary analysis of cross-sectional data (2021) (2)
- A xanthene derivative, DS20060511, attenuates glucose intolerance by inducing skeletal muscle-specific GLUT4 translocation in mice (2021) (2)
- Correction to: Metabolic surgery in treatment of obese Japanese patients with type 2 diabetes: a joint consensus statement from the Japanese Society for Treatment of Obesity, the Japan Diabetes Society, and the Japan Society for the Study of Obesity (2021) (1)
- Deletion of skeletal muscle Akt1/2 causes osteosarcopenia and reduces lifespan in mice (2022) (1)
- [Mutations in the mitochondrial gene in patients with NIDDM]. (1994) (1)
- [Mechanisms by which PPAR gamma modulators regulate insulin sensitivity]. (2002) (1)
- Diagnostic ability using fatty liver and metabolic markers for metabolic‐associated fatty liver disease stratified by metabolic/glycemic abnormalities (2022) (1)
- 1325-P: Effectiveness of Comprehensive Gene Panel-Based Next-Generation Sequencing with Phenotype-Driven Bioinformatics Analysis for Diagnosis of Atypical Diabetes (2019) (1)
- Molecular Pathogenesis of Type 2 Diabetes Mellitus and Obesity in Knockout Mice Models (2000) (1)
- 1876-P: Gut Microbial Fermentation of Polysaccharides Impacts Insulin Resistance in Humans (2020) (1)
- Potassium concentration in initial fluid therapy and in-hospital mortality of patients with diabetic ketoacidosis. (2021) (1)
- Major complications after percutaneous biopsy of native or transplanted liver in pediatric patients: a nationwide inpatient database study in Japan (2022) (1)
- Vascular Endothelial Growth Factor Induces Activation and Subcellular Translocation of Focal Adhesion Kinase (p125) in Cultured Rat Cardiac Myocytes (1999) (1)
- Akt1 in Osteoblasts and Osteoclasts Controls Bone (2007) (1)
- [Adiponectin receptor-targeted therapy for lifestyle-related diseases]. (2016) (1)
- Abstract LB-174: Genome-wide association meta-analysis identifies novelGP2gene risk variants for pancreatic cancer in the Japanese population (2019) (1)
- Pseudo‐hyperglucagonemia was observed in pancreatectomized patients when measured by glucagon sandwich enzyme‐linked immunosorbent assay (2020) (1)
- Long-Term Pancreas Allograft Survival in Simultaneous Pancreas-Kidney Transplantation by Era. (2015) (1)
- Efficacy of the Self-management Support System DialBetesPlus for Diabetic Kidney Disease: Protocol for a Randomized Controlled Trial (2021) (1)
- The sodium‐glucose co‐transporter 2 inhibitor tofogliflozin suppresses atherosclerosis through glucose lowering in ApoE‐deficient mice with streptozotocin‐induced diabetes (2022) (1)
- Lactic acidosis due to attempted suicide with metformin overdose: A case report. (2016) (1)
- Clinical care and other categories posters: Incretin therapies (2019) (1)
- Pathogen-induced systemic plant signal triggers DNA rearrangements (2003) (1)
- [Epigenetics and Life-style diseases]. (2016) (1)
- [New diagnostic criteria of diabetes mellitus in Japan, 2010]. (2010) (1)
- [New drug targets for the metabolic syndrome and obesity]. (2012) (1)
- A Machine Learning-Based Predictive Model to Identify Patients Who Failed to Attend a Follow-up Visit for Diabetes Care After Recommendations From a National Screening Program. (2022) (1)
- [New diabetes mellitus models: gene targeting]. (1998) (1)
- [The Update of Obesity Syndrome: Molecular Mechanism, Pathophysiology and Therapies. Topics: II. Recent Topics on Care and Treatment of the Obesity Syndrome; 3. Pharmacotherapy of obesity]. (2015) (1)
- [Smoking scenes in Japanese television dramas]. (2003) (1)
- Societal Marketing in the Treatment of Type 2 Diabetes Mellitus: A Longitudinal Questionnaire Survey for Michelin-Starred Restaurants in Japan (2019) (1)
- Voices: Insulin and beyond. (2021) (1)
- Betel Chewing and Risk of Metabolic Disease, Cardiovascular Disease, and All-Cause Mortality: A Meta-Analysis. (2014) (1)
- Body Composition is Main Determinant for the Difference in Type 2 Diabetes Pathophysiology between Japanese and Caucasians Short running title: Type 2 Diabetes in Japanese and Caucasians (2013) (1)
- 887-P: Development of the Noninvasive Diabetes Monitoring Method (2020) (1)
- [108th Scientific Meeting of the Japanese Society of Internal Medicine: invited lecture: 4. Molecular mechanism and treatment strategy of type 2 diabetes]. (2011) (1)
- Sweat gland atrophy of the heel in diabetic patients with angiopathy. (2013) (1)
- Corrigendum to "Lipoprotein-associated phospholipase A2 is related to risk of subclinical atherosclerosis but is not supported by Mendelian randomization analysis in a general Japanese population." [Atherosclerosis 246 (March 2016) 141-147]. (2018) (1)
- [Endothelial function and insulin resistance]. (2008) (1)
- 53 Involvement in the Pathogenesis of Fatty Liver Disease * (2004) (1)
- Comprehensive IDF-WPR diabetes and disasters manual, 2nd edition available. (2022) (1)
- Safety and efficacy of switching thrice-daily treatment with NovoRapid®70Mix (BIAsp70) to BIAsp70 before breakfast and lunch and NovoRapid®30Mix (BIAsp30) before dinner in patients with type 2 diabetes: subgroup analysis of a phase III trial (2011) (1)
- [Recent advances in PPARs research--basic and clinical aspects]. (2005) (1)
- Vascular Endothelial Growth Factor Induces Activation and Subcellular Translocation of Focal Adhesion Kinase (p125 FAK ) in Cultured Rat Cardiac Myocytes (1999) (1)
- ASSOCIATION OF DONOR-SPECIFIC HLA ANTIBODY WITH ACUTE REJECTION IN LIVING-DONOR LIVER TRANSPLANTATION: A POSSIBLE EVIDENCE OF HUMORAL SENSITIZATION: 3230 (2010) (1)
- [Gene targeting approaches for diabetes research]. (2005) (1)
- [Insulin resistance in central nerve system]. (2006) (1)
- Differential effects of diet- and genetically-induced brain insulin resistance on amyloid pathology in a mouse model of Alzheimer’s disease (2019) (1)
- [Glucokinase knockout mice]. (1998) (1)
- O-46: Insulin signalling and insulin actions in the muscle, adipose tissue and liver of insulin resistant IRS-1 deficient mice (2009) (1)
- [Diagnostic standard for fasting and postprandial hyperglycemia]. (2009) (1)
- Impairment of M2a-Subtype Macrophage Activation by Il-4-Irs2 Pathway in Obesity (2018) (1)
- Comment on: Lin et al. Long-Term Changes in Adiposity and Glycemic Control Are Associated With Past Adenovirus Infection. Diabetes Care 2013;36:701–707 (2013) (1)
- Reply: Injection of embryo culture supernatant prior to blastocyst transfer—cofactor? (2008) (1)
- [Role of NADH shuttle system in glucose-stimulated insulin secretion]. (2002) (1)
- Effects of Liraglutide on (cid:1) -Cell-Specific Glucokinase-Deficient Neonatal Mice (2012) (1)
- ADDITION-Europe: the first decade and beyond. (2019) (1)
- Effect of a Multifactorial Intervention on Fracture in Patients With Type 2 Diabetes: Subanalysis of the J-DOIT3 Study (2021) (1)
- Feasibility, acceptability, and effects of a self-stigma reduction pilot program for Japanese individuals with type 2 diabetes (2023) (1)
- [Developing Exercise-mimicking Drugs toward Realization of Preemptive Medicine for Lifestyle-related Diseases.] (2018) (1)
- [IRS-1 knockout mouse]. (1998) (1)
- RNA Interference Technology: Generation of highly specific vector-based shRNAi libraries directed against the entire human genome (2005) (1)
- [Mutations in the insulin receptor gene in patients with genetic forms of insulin resistance]. (1991) (1)
- Association Between Plasma Triglycerides and HDL-Cholesterol and Microvascular Kidney Disease and Retinopathy in Type 2 Diabetes : A Global Case-Control Study in 13 Countries Running title : (2013) (1)
- Corrigendum: Combating diabetes and obesity in Japan (2006) (1)
- [The role of phosphorylation cascade in insulin action]. (1994) (1)
- Synthetic gene circuits: Insulin self-regulation (2017) (1)
- NFIA determines the cis-effect of genetic variation on Ucp1 expression in murine thermogenic adipocytes (2022) (1)
- Insulin, bombyxin and their hybrids: Synthesis and activity (1993) (1)
- Sodium-Glucose Cotransporter 2 Inhibitors for Type 1 Diabetes Mellitus—Systematic Review and Meta-analysis (2018) (1)
- Adiponectin and its receptors in insulin resistance, diabetes, and metabolic syndrome, and obesity (2008) (1)
- Issue Information (2018) (0)
- 4. Molecular Mechanism and Treatment Strategy of Type 2 Diabetes. (2011) (0)
- OE-318 Maintenance of Cardiac and Adipose PAI-1 Expression Despite the Lack of IRS-1 : a Knockout Mouse Study(Diabetes/Obesity 2 (H) : OE40)(Oral Presentation (English)) (2004) (0)
- Subacute adrenal hemorrhage by blunt abdominal contusion during snowboarding (Case report) (2008) (0)
- Insulin-like Growth Factor I (IGF-I) Therapy in a Patient with Severe Insulin Resistance Syndrome (1994) (0)
- A Case of Diabetic Amyotrophy Mitochondria ) tRNA ( leu ; UUR ) Therapy with Coenzyme Q 10 Associated with 3243 Mutation and Successful (2006) (0)
- [Neurofibrosarcoma of the perineum associated with von Recklinghausen's disease: a case report and review of the literature]. (1983) (0)
- Structural basis of ethnic-specific variants of PAX 4 associated with type 2 1 diabetes 2 3 (2020) (0)
- COVID‐19 in a neurofibromatosis 1 patient accompanied by brain tumor hemorrhage (2022) (0)
- Session 1 S 1-1 AMP-activated protein kinase in CRH neurons in the PVH controls food selection behavior (2014) (0)
- [Classification of mutations in the insulin receptor gene]. (1994) (0)
- Comparison of bleeding complications after pediatric kidney biopsy between intravenous sedation and general anesthesia: a nationwide cohort study (2023) (0)
- SUBACUTE ADRENAL HEMORRHAGE BY BLUNT ABDOMINAL CONTUSION DURING SNOWBOARDING SUBACUTE ADRENAL HEMORRHAGE BY BLUNT ABDOMINAL CONTUSION (2008) (0)
- Patient referral flow between physician and ophthalmologist visits for diabetic retinopathy screening among Japanese patients with diabetes: A retrospective cross-sectional cohort study using the National Database. (2023) (0)
- [A case of vesicosigmoidal fistula]. (1988) (0)
- Abstract P321: Influence of Cigarette Smoking on Coronary and Aortic Calcification Among Community-based Middle-aged Japanese and Korean Men (2012) (0)
- Obesity and diseases. 3. Molecular mechanisms of obesity and insulin resistance. (1998) (0)
- Development of a high-performance liquid chromatographic glycated albumin assay using finger-prick blood samples. (2023) (0)
- Robust and highly efficient hiPSC generation from patient non-mobilized peripheral blood-derived CD34+ cells using the auto-erasable Sendai virus vector (2019) (0)
- Adiponectin is an endogenous anti-fibrotic mediator and therapeutic target (2017) (0)
- Human adiponectin receptor AdipoR1 assumes closed and open structures (2020) (0)
- Multi-ancestry genome-wide study in >2.5 million individuals reveals heterogeneity in mechanistic pathways of type 2 diabetes and complications (2023) (0)
- A xanthene derivative, DS20060511, attenuates glucose intolerance by inducing skeletal muscle-specific GLUT4 translocation in mice (2021) (0)
- Blood levels of nicotinic acid negatively correlate with hearing ability in healthy older men (2023) (0)
- Pivotal role of inter-organ aspartate metabolism for treatment of mitochondrial aspartate-glutamate carrier 2 (citrin) deficiency, based on the mouse model (2019) (0)
- Role of insulin receptor substrates in the progression of hepatocellular carcinoma (2017) (0)
- Communications antenna for CS-2 (1982) (0)
- Mo-P1:45 Prediction of cardiovascular death by self-reported past history of hypertension in a 19-year cohort study in Japan (2006) (0)
- Mo-P1:63 Association between family history of stroke and mortality from ischemic stroke among Japanese (2006) (0)
- 1086-P: A Retrospective Nationwide Surveillance on the First-Line Antidiabetic Medication for the Patients with Type 2 Diabetes in Japan (2021) (0)
- Abstract 4942: Identification of Insulin Receptor Substrate Family Proteins Mediating PAI-1 Production in Cardiac and Adipose Tissues From IRS-1 Null Mice (2006) (0)
- Signaling Pathway Proliferation and Migration via the ERK Healing by Promoting Keratinocyte Adiponectin Regulates Cutaneous Wound (2012) (0)
- [Perspective for development of insulin sensitizers]. (2002) (0)
- Midlobular zone 2 hepatocytes: A gatekeeper of liver homeostasis. (2021) (0)
- [Hypoglycemic agents to improve insulin resistance]. (2000) (0)
- Running title : Cell interactions in adipogenesis (2007) (0)
- 1A2-O08 Simultaneous measurement system of plantar pressure and shear forces to identify factors associated with callus in diabetic patients(Nursing and Mechatronics) (2012) (0)
- Peroxisome Proliferator-Activated Receptor &ggr; Plays a Critical Role in Inhibition of Cardiac Hypertrophy In Vitro and In Vivo (2002) (0)
- Abstract 2837: Adiponectin knockout enhances intestinal carcinogenesis in Min and wild-type mice (2011) (0)
- Effect of Branched-Chain Amino Acid Infusion on In-Hospital Mortality of Patients With Hepatic Encephalopathy and End-Stage Kidney Disease: A Retrospective Cohort Study Using a National Inpatient Database. (2021) (0)
- Severe aortic stenosis during leptin replacement therapy in a patient with generalized lipodystrophy‐associated progeroid syndrome due to an LMNA variant: A case report (2022) (0)
- [Disease concept of type 2 diabetes]. (2012) (0)
- Abstract 13031: Universal Screening for Familial Hypercholesterolemia in Young Adults: The Young FH Study (2020) (0)
- Role of mitochondrial NADH shuttle system in acute amylase secretion by acetylcholine from mouse pancreatic acinar cells. (2002) (0)
- Abstract 394: Posttranslational Modification Of Klf5 Mediates Metabolic Dysfunction And Vascular Disease In Metabolic Syndrome (2007) (0)
- Role of Structural Biology for Target Molecules of Diseases in Drug Development (2012) (0)
- Abstract 3643: Consciousness of Reduced Salt Diet and Actual Achievement of Salt Reduction Estimated from 24hr Urinary Na Excretions in General Populations in Japan, PRC, UK and US: The INTERMAP Study (2007) (0)
- Treatment patterns and satisfaction in patients with type 2 diabetes newly initiating oral monotherapy with antidiabetic drugs in Japan: results from the prospective Real-world Observational Study on Patient Outcomes in Diabetes (RESPOND) (2022) (0)
- Identification of serum metabolome signatures associated with retinal and renal complications of type 2 diabetes (2023) (0)
- Erratum: Psychological Factors, Coffee and Risk of Diabetes Mellitus among Middle-Aged Japanese: a Population-Based Prospective Study in the JPHC Study Cohort [Endocrine Journal Vol. 56 (3): 459-468, 2009] (2011) (0)
- Issue Information (2017) (0)
- Alcohol consumption and subclinical and clinical coronary heart disease: A Mendelian randomization analysis. (2022) (0)
- Role of the liver in glucose homeostasis in PI 3-kinase p85 (cid:1) -deficient mice (2009) (0)
- Evi1 Is a Stem Cell-Specific Regulator of Self-Renewal Capacity In the Definitive Hematopoietic System (2010) (0)
- Abstract 11292: Modulation of Lipoprotein and Glucose Metabolism with the Over-expression of Niemann-pick C1 Like 1 Protein (NPC1L1) In Mice Liver (2010) (0)
- Issue Information (2019) (0)
- Real-World Evidence of Treatment with Teneligliptin/Canagliflozin Combination Tablets for Type 2 Diabetes Mellitus: A Post-Marketing Surveillance in Japan (2022) (0)
- [Impaired glucose tolerance (IGT): current understanding and future research directions]. (2005) (0)
- Elucidating exercise-induced skeletal muscle signaling pathways and applying relevant findings to preemptive therapy for lifestyle-related diseases. (2021) (0)
- Analysis ofthestructural features oftheC-terminus ofGLUT1that are required fortransport catalytic activity (1995) (0)
- Serum n 2 6 fatty acids and lipoprotein subclasses in middle-aged men : the population-based cross-sectional ERA-JUMP Study 1 – 3 (2010) (0)
- [Protein kinase C activation and diabetic complications]. (2005) (0)
- Abstract P084: Influence Of Amount And Rapidity Of Weight Loss On The Risk Of Subsequently Regaining Weight And Drop-out From Treatment Among Patients With Severe Obesity Dieting In Hospital Without Bariatric Surgery (2014) (0)
- Issue information (2019) (0)
- AdipoR agonist increases insulin sensitivity and exercise endurance in AdipoR-humanized mice (2021) (0)
- Comprehensive evaluation of type 2 diabetes susceptibility loci in the Japanese population by using 1000 Genomes Project data (2012) (0)
- [Defects in insulin's signalling process and diabetes mellitus]. (1997) (0)
- Characteristics of subjects with type 2 diabetes enrolled in randomized controlled trials and non‐randomized controlled trials in Japan: A systematic review (2022) (0)
- Polymorphism of the Angiotensinogen Gene and Hypertension in a Japanese General Population (the Shigaraki Study) (2003) (0)
- RELATIONSHIP BETWEEN OBSTRUCTIVE SLEEP APNOEA, OTHER CARDIOVASCULAR RISK FACTORS AND CARDIOVASCULAR DISEASE (2018) (0)
- Abstract P363: Cross-Sectional Comparison of Coronary Artery Calcium Prevalence between Japan and the US: The Multi-Ethnic Study of Atherosclerosis (MESA) and the Shiga Epidemiological Study of Subclinical Atherosclerosis (SESSA) (2013) (0)
- O-45: Annexin II — a novel element in insulin signal transduction: role of annexin-II phosphorylation in insulin receptor internalization (2009) (0)
- Abstract 5466: In Vivo Molecular Imaging Revealed Chronic Inflammation and Increased Adhesion Molecules in Obese Adipose Tissue in Mice (2008) (0)
- Influence of Recipient Age On Long-Term Simultaneous Pancreas Kidney Transplants: An Analysis of UNOS Data.: Abstract# B1276 (2014) (0)
- Insulin Receptor Substrate-2 (Irs2) in Endothelial Cells Plays a Crucial Role in Insulin (2015) (0)
- Abstract 1614: Neutral Cholesterol Ester Hydrolase is Essential for Cholesterol Removal in Human Macrophages and Atherosclerosis (2009) (0)
- YI-838 KLF5 PLAYS A PIVOTAL ROLE IN METABOLIC REGULATION AND ATHEROSCLEROSIS (2007) (0)
- Corrigendum to ‘Gamma-Glutamyltransferase and mortality risk from heart disease and stroke in Japanese men and women: NIPPON DATA 90’ (2011) (0)
- [Practice guidelines review: Diabetes mellitus]. (2002) (0)
- Agents ameliorant la resistance a l'insuline (2002) (0)
- Abstract 2770: Difference in Serum Levels of Docosahexaenoic Acid (DHA) May Explain the Difference in Carotid Intima-Media Thickness Between US White and Japanese Men Aged 40 49 (2006) (0)
- Evaluation of glycated albumin levels in tears and saliva as a marker in patients with diabetes mellitus. (2023) (0)
- Cholesteryl Ester Transfer Protein, Coronary Calcium and Intima-media Thickness of the Carotid Artery in Middle-Aged Japanese Men (2010) (0)
- Hyponatremia and Sulfonylureas: A Reply (1984) (0)
- BRACHIAL-ANKLE PULSE WAVE VELOCITY IS ASSOCIATED WITH CORONARY CALCIFICATION AMONG 1,131 HEALTHY MIDDLE-AGED MEN (2015) (0)
- Correction: Potential Formula for the Calculation of Starting and Incremental Insulin Glargine Doses: ALOHA Subanalysis (2014) (0)
- Abstract 2319: Genetic Variations Of Mrf-2/Arid5b Confer Risk Of Coronary Artery Disease And Diabetes Mellitus In The Japanese Population (2007) (0)
- Abstract P069: The Relationship of Serum Marine-Derived N-3 Fatty Acids and Carotid Intima-Media Thickness among General Japanese Men: The Shiga Epidemiological Study of Subclinical Atherosclerosis (SESSA) (2013) (0)
- Naoto Cardiac Hypertrophy In Vitro and In Vivo Plays a Critical Role in Inhibition of γ Peroxisome Proliferator-Activated Receptor (2002) (0)
- Crystal structure of the human adiponectin receptor 1 D208A mutant (2020) (0)
- Hepatic Sdf2l1 controls feeding-induced ER stress and regulates metabolism (2019) (0)
- PJ-296 Heterozygous PPAR γ Deficient Mice Showed Increased Neointima Formation with Vascular Smooth Muscle Cell Proliferation in Response to Cuff Injury(Atherosclerosis, Basic 3 (IHD) : PJ50)(Poster Session (Japanese)) (2004) (0)
- A transgenic mutant mouse line accompanied by the complete deletion of interleukin-33 showed insulin and leptin resistances (2018) (0)
- [Molecular pathogenesis of type 2 diabetes mellitus]. (1999) (0)
- patients The Residual Risk Reduction Initiative: a call to action to reduce residual vascular risk in dyslipidaemic (2011) (0)
- Vascular Intima Formation in Insulin Receptor Substrate-2 Deficient Mice (2002) (0)
- [Knockout mouse models for type 2 diabetes. Mice with impaired insulin secretion]. (2002) (0)
- [Adipocytes and bone metabolism]. (2011) (0)
- Issue Information (2015) (0)
- Smartphone-Based Self Management System for Type-2 Diabetes Patients (2012) (0)
- Anti-Obese Hormone Adiponectin Regulates Emergency Hematopoiesis and Antibacterial Response Through Downregulation Of Socs3 In Hematopoietic Progenitor Cells (2013) (0)
- OriginatArticle SP ' e " : ciii-[ i = ii ialIssuec , The Evaluation ofMaterials to Provide Health-Related Information as a Population Strategy in the Worksite : The High-Risk and Population Strategy for Occupational Health Promotion ( HIPOP-OHP ) Study (2017) (0)
- Significant inverse associations of serum n-6 fatty acids with plasma plasminogen activator inhibitor-1 (2012) (0)
- Issue Information (2016) (0)
- A Novel Xanthene Derivative, DS20060511, Attenuates Glucose Intolerance by Inducing Skeletal Muscle-specific GLUT4 Translocation in Diabetic Mice (2020) (0)
- [Knockout mouse models for type 2 diabetes. Mice with insulin resistance]. (2002) (0)
- Differential roles of insulin and IGF-1 in murine keratinocyte differentiation (2000) (0)
- Mo-P1:48 Long-term outcome after stroke among the participants of the national survey on circulatory disordeers in Japan (Nippon Data80, 1980–1994) (2006) (0)
- Physiological roles of adiponectin and adiponectin receptors (2006) (0)
- [113th Scientific Meeting of the Japanese Society of Internal Medicine: Symposium: Insight into the Mechanism of Diseases on New Perspective Arising in Internal Medicine: From Epigenetics to Organ Associations: Novel Insight into Physiological and Pathophysiological Roles of Adipocytes -Elucidation (2016) (0)
- Additions and Corrections (2006) (0)
- [Pathophysiological roles of adipocytokines in the development of insulin resistance]. (2012) (0)
- Adiponectin receptors AdipoR (2011) (0)
- Abstract 14137: A Newly Identified Case of Apolipoprotein C-II Deficiency Associated with Reduced Transcriptional Activity (2010) (0)
- Genetic Factor and Molecular Pathogenesis of Diabetes (2002) (0)
- Takashi Kadowaki and Naoto Kubota Protective Role of Imatinib in Atherosclerosis (2004) (0)
- 2P-0348 EBT (electron-beam CT) and risk factor assessment among Japanese and US men in the post World War II birth cohort: ERA-JUMP (2003) (0)
- Prediction of pregnancy and delivery rates by blastocyst morphological score and age, based on 1488 single frozen-thawed blastocyst transfer cycles (2010) (0)
- Diminished Left Ventricular Function and Coronary Perivascular Fibrosis Associated with Insulin Resistance do not Require Insulin Receptor Substarte-1 Mediated Signaling (2002) (0)
- [Aging and homeostasis. Development of novel AdipoR-targeted drugs with exercise-mimicking and anti-aging properties.] (2017) (0)
- Issue Information (2018) (0)
- Role of the insulin receptor kinase activity in insulin action. (1988) (0)
- Ensuring Success for J-NIH (2013) (0)
- Influence of Insulin Receptor Substrate–2–Knockout on the Activity of Experimental Choroidal Neovascular in Mice Model (2006) (0)
- PL01 MOLECULAR BIOLOGY OF TYPE II DIABETES (2006) (0)
- Association of Anti-HLA Antibody with Operational Tolerance in Pediatric Living-Donor Liver Transplantation: A Possible Evidence of Humoral Sensitization: 1531 (2012) (0)
- A method of selectively testing of adiponectinmultimeren (2004) (0)
- Efficacy of the Self-management Support System DialBetesPlus for Diabetic Kidney Disease: Protocol for a Randomized Controlled Trial (Preprint) (2021) (0)
- Crystal structure of the human adiponectin receptor 1 (2015) (0)
- Lack of Brain Insulin Receptor Substrate-1 (IRS1) Causes Growth Retardation via Growth Hormone Releasing Hormone (2018) (0)
- Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population (2019) (0)
- Class IA PI3K is involved in the pre-B cell antigen receptor-mediated signaling (86.6) (2007) (0)
- 2) Treatment Strategies for Preventing Atherosclerosis in Patients with Diabetes Mellitus. (2010) (0)
- 4. Recent Topics of the Mechanism and Treatment of Diabetes Mellitus (2009) (0)
- [Current status of analysis of type 2 diabetes genes]. (2002) (0)
- 2P-0323 What cause of mortality can we predict by high density lipoprotein cholesterol (HDLC) in the Japanese general population? NIPPONDATA90 (2003) (0)
- Tu-P7:53 KLF5 is involved in both metabolic regulation and atherosclerotic lesion formation (2006) (0)
- Issue Information (2017) (0)
- Mo-P1:58 The relationship between alcohol intake and traditional or non-traditional risk factors for cardiovascular disease in the middle-aged Japanese men (2006) (0)
- Echinomycin inhibits adipogenesis in 3T3-L1 cells in a HIF-independent manner (2017) (0)
- Brief Genetics Report A Polymorphism in the AMPK (cid:1) 2 Subunit Gene Is Associated With Insulin Resistance and Type 2 Diabetes in the Japanese Population (2006) (0)
- Chair’s Summary (2011) (0)
- Abstract 5475: A Novel Lipase, Neutral Cholesteryl Ester Hydrolase, is a Major Regulator of Neutral Cholesteryl Ester Hydrolysis in Murine Macrophages. (2008) (0)
- Prediction of the efficacy and safety of pioglitazone in patients with type 2 diabetes mellitus (2005) (0)
- Adiponectin is a potent inhibitor of gastric cancer. (2006) (0)
- Co-localization of NFIA and PPARγ controls the brown fat gene program (2016) (0)
- P-241 Associations of CRP and Fibrinogen with Subclinical Atherosclerosis in Whites in US, Japanese-American in Hawaii and Japanese in Japan (2009) (0)
- Abstract 17671: The Critical Role of Sterol Regulatory Element-binding Protein-1c in Hypertriglyceridemia Caused by Apolipoprotein A5 Deficiency (2016) (0)
- , R receptor substrate 1-deficient mice . muscles and livers of insulin-resistant , insulin Insulin signalling and insulin actions in the (1996) (0)
- Using mHealth to Provide Mobile App Users With Visualization of Health Checkup Data and Educational Videos on Lifestyle-Related Diseases: Methodological Framework for Content Development (Preprint) (2020) (0)
- Preface (1992) (0)
- Ka-band communications antenna for Superbird (1990) (0)
- Human Brown Adipose Tissue Density Assessed by Near-Infrared Time-Resolved Spectroscopy Inversely Correlates with the Body Mass Index in Patients with Type 2 Diabetes (2018) (0)
- Cognitive impairment and task-specific incident disability: Japanese cohort study (2006) (0)
- Issue Information (2017) (0)
- Mo-P1:31 Influence of cigarette smoking on coronary and aortic calcification among community-based Japanese young men (2006) (0)
- The Prevalence of Gastrointestinal Symptoms Depends on Disease Duration and Gastrointestinal Tract Region in Patients with Type 2 Diabetes (2018) (0)
- Impact of body mass index on in-hospital mortality in older patients hospitalized for bacterial pneumonia with non-dialysis-dependent chronic kidney disease (2022) (0)
- NFIA Controls Brown-Fat Gene Program by Differential Chromatin Remodeling of Cell Type-Specific Enhancers (2015) (0)
- Safety and efficacy of teneligliptin, a dipeptidyl peptidase-4 inhibitor, in monotherapy and in combination therapy with antihyperglycemic agents in patients with type 2 diabetes mellitus - An interim analysis of post-marketing surveillance, RUBY- (2018) (0)
- 3P-0712 Heterozygous PPAR γ deficient mice showed impaired endothelium-dependent vascular relaxation and increased neointima formation in response to cuff injury (2003) (0)
- Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases (2020) (0)
- Tu-P9:344 The metabolic syndrome and preclinical atherosclerosis in middle-aged Japanese men (2006) (0)
- KLF5 is important for both metabolic regulation and atherosclerotic lesion formation (2006) (0)
- Selective Ablation of IRS-1 Decreases Cardiac Contractility without Attenuating PAI-1 Expression or Perivascular Fibrosis (2003) (0)
- Adipose Tissue Remodeling, Chronic Inflammation and T-cell-macrophage Interactions in Obesity Visualized by in vivo Molecular Imaging Method (2009) (0)
- Association of serum n 2 6 and n 2 3 polyunsaturated fatty acids with lipids in 3 populations of middle-aged men 1 – 3 (2009) (0)
- Tofogliflozin Suppresses the Progression of Atherosclerosis and Reduces Inflammation in Macrophages of STZ-Diabetic ApoE KO Mice due to Improvement of Glucose Tolerance (2018) (0)
- PE-537 Identification of the Novel MEF2-Kruppel-like Factor 5 (KLF5) Network That Associates with Cardiovascular Disease(Molecular biology, vascular-3, The 71st Annual Scientific Meeting of the Japanese Circulation Society) (2007) (0)
- Evaluation of Pancreatic Graft Function Using 11C-Methionine Positron Emission Tomography in Pancreas Transplantation. K. Otsuki,1 (2017) (0)
- [A trend of insulin sensitizer which is under development]. (2001) (0)
- Abstract P305: Incidence of Coronary Artery Calcification and Its Association With Eicosapentaenoic Acids From The ERA JUMP Study (2012) (0)
- [Obesity and diseases. 3. Obesity and molecular structure of insulin resistance]. (1998) (0)
- Mo-P1:137 Electrocardiogram screening for left high R-wave predicts cardiovascular death in a Japanese community-based population; Nippon data90 (2006) (0)
- DOES CHRONIC INTERMITTENT HYPOXIA ALWAYS INCREASE BLOOD GLUCOSE LEVELS IN MICE? (2018) (0)
- [Trends in therapy for diabetes mellitus]. (2002) (0)
- [Perspective for personalized medicine for diabetes]. (2002) (0)
- Diagnosis, Prevention, and Treatment of Cardiovascular Diseases in People With Type 2 Diabetes and Prediabetes (2020) (0)
- [Diabetic treatment strategies to control the onset and development of diabetic macrovascular disease]. (2010) (0)
- [Diabetes and the metabolic syndrome]. (2006) (0)
- Authors' Response to a Letter to the Editor Re: Differences Between Patient-Reported Versus Clinician-Observed Nonulcerative Signs and Symptoms of the Foot in Patients With Diabetes Mellitus. J Wound Ostomy Continence Nurs. 2019;46(2): Differences Between Patient-Reported Versus Clinician-Observed N (2019) (0)
- Regulation of Chronic Myelogenous Leukemia Stem Cells by Leukemia Oncogene Evi1 (2011) (0)
- 5. Patients with Diabetes Difficult to Manage and Their Countermeasures (2018) (0)
- Selective ablation of insulin receptor substrate-1 decreases cardiac contractility in vivo without attenuating PAI-1 expression or perivascular fibrosis (2003) (0)
- [Importance of animal models by gene targeting in diabetes research]. (2002) (0)
- [Functional food component--osmotin]. (2012) (0)
- [Mitochondria gene mutation and diabetes]. (1996) (0)
- Tu-W22:1 Role of adipokines in obesity-linked insulin resistance, metabolic syndrome and atherosclerosis (2006) (0)
- NFIA Colocalizes with PPARgamma and Activates the Cell-Type–Specific Enhancers to Control the Brown Fat Gene Program (2018) (0)
- ABBREVIATIONS MODY : maturation onset diabetes mellitus of the young MODY 2 : maturation onset diabetes mellitus of the young (2004) (0)
- Effect modification of diabetes as a comorbidity on temperature variability and hospitalization for cardiovascular disease (2022) (0)
- PPAR participates in both vasculogenesis and angiogenesis. (2004) (0)
- Structural basis of ethnic-specific variants of PAX4 associated with type 2 diabetes (2021) (0)
- Long-term pancreas allograft survival in simultaneous pancreas-kidney transplantation by era. (2010) (0)
- PE-411 KLF5 Controls Metabolic Stress Response in Metabolic Syndrome and Cardiovascular Disease(Diabetes/Obesity/Metabolic syndrome-05, The 71st Annual Scientific Meeting of the Japanese Circulation Society) (2007) (0)
- Issue Information (2016) (0)
- Issue Information (2018) (0)
- [Recent advances in PPARgamma research]. (2010) (0)
- characterized by an impaired response to GP VI stimulation null platelets α Functional phenotype of phosphoinositide 3-kinase p85 (2003) (0)
- The mechanism by which adipocytes regulate insulin sensitivity (2004) (0)
- JCB_201410052 1..14 (2015) (0)
- [Assessment of insulin resistance by minimal model analysis]. (1997) (0)
- Genotype–Phenotype Correlations and Structural Basis of INSR and IGF1R Mutations Causing Severe Insulin/IGF-1 Resistance (2018) (0)
- [Action plan 2010 of Japan Diabetes Society (DREAMS)]. (2012) (0)
- Crystal structure of the human adiponectin receptor 2 (2015) (0)
- 0863 ANALYSIS OF FOCAL ADHESION RELATED TYROSINE KINASE IN CARDIAC MYOCYTE STIMULATED BY VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) (1997) (0)
- HYPERTENTION IN THE ELDERLY: ANALYSES ON NIPPON DATA80, 1980-94 (2004) (0)
- 926-P: Cardiovascular (CV) and Hypoglycemia Outcomes across Age Groups in People with Type 2 Diabetes (T2D) in the CAROLINA Trial (2020) (0)
- A method for sample pretreatment and immunological assay method using thereof (2004) (0)
- Organizing Committee and International Advisory Board (2012) (0)
- OE-316 Kruppel-like family of transcription factor 5 is required for adipocyte differentiation(Diabetes/Obesity 2 (H) : OE40)(Oral Presentation (English)) (2004) (0)
- ' s response to reviews Title : Population Attributable Fraction of Smoking and Metabolic Syndrome on Cardiovascular Disease Mortality in Japan : a 15-Year Follow Up of NIPPON DATA 90 (2010) (0)
- Issue Information (2016) (0)
- The Insulin Receptor Protein Kinase (1986) (0)
- [Signaling molecules as the therapeutic targets for the metabolic syndrome]. (2006) (0)
- Molecular Pathogenesis of Type 2 Diabetes in Knockout Mice Models (2000) (0)
- For peer review only Impact of Male Pattern Baldness on Coronary Heart Disease: A meta-analysis (2012) (0)
- C-terminal globulardomäne of adiponectin for treatment of atherosclerosis (2003) (0)
- Molecular analysis of Cardiac Hypertrophy by Mechanical Stress:Involvement of Stretch-Induced Protein Kinase Cascade (1993) (0)
- [Genetic factors and life styles related to diabetes mellitus--with special reference to multiple factor inheritance]. (2000) (0)
- Abstract 5276: Sumoylation Of Klf5 Is A Molecular Switch Regulating Ppar-{delta}-containing Transcriptional Programs Of Lipid Metabolism (2008) (0)
- CDK5 Regulatory Subunit-Associated Protein 1-like 1 Negatively Regulates Adipocyte Differentiation through Activation of Wnt Signaling Pathway (2017) (0)
- [Questionnaire survey of the POCT device antsense ROSE for blood glucose analysis on healthcare professionals--evaluation focused on preventive measures against cross-infections]. (2011) (0)
- Issue Information (2016) (0)
- Pathogenesis of NIDDM with a particular emphasis on molecular defects (1996) (0)
- 1741-P: Immune Regulation of Postprandial Glycemia and Whole-Body Insulin Sensitivity through Myeloid Production of IL-10 (2020) (0)
- Lack of Insulin Receptor Substrate-2 Is a Link between Insulin Resistance and an Increased Intima of the Vessel in Mice (2003) (0)
- Our sympathies to the people affected by the Great East Japan Earthquake, and the activities of the Japan Diabetes Society (2011) (0)
- 55-OR: Oral Semaglutide vs. Liraglutide and Placebo in T2D: PIONEER 4 (2019) (0)
- [The roles of adipokines in the regulation of insulin sensitivity]. (2006) (0)
- [MODY (maturity-on-set diabetes of the young)]. (1998) (0)
- Issue Information (2016) (0)
- Abstract 3901: Evi1 defines leukemia-initiating capacity and tyrosine kinase inhibitor resistance in chronic myeloid leukemia (2014) (0)
- PDB7 Treatment of Type 2 Diabetes in JAPAN: An Evidence GAP Analysis Based on Systematic and Target Literature Review of Clinical Studies (2020) (0)
- [Glucokinase gene and its dual promoter regions]. (1997) (0)
- [113th Scientific Meeting of the Japanese Society of Internal Medicine: Presidential Lecture: Elucidation of Pathogenesis and Development of Therapeutic Strategy of Type 2 Diabetes -Progress in the Thirty Years]. (2016) (0)
- Issue Information (2016) (0)
- Genotype-Structure-Phenotype Correlations of Disease-Associated IGF1R Variants and Similarities to Those of INSR Variants (2021) (0)
- Signal Insulin Transduction-Like Growth Mechanism Factor-1 of Insulin and (2006) (0)
- Deregulation of Pancreas-Specific Oxidoreductin ERO1β in the Pathogenesis of 1 (2014) (0)
- We-P11:12 Relationship of coronary heart disease mortality to casual blood glucose level and self-reported past history of diabetes mellitus (2006) (0)
- Abstract P377: Prevalence of Carotid Plaque and Cardiovascular Risk Factors Among 40-49 Year Old White, Japanese American, Japanese in Japan and Korean Men from the ERA JUMP Study (2013) (0)
- Faculty Opinions recommendation of Insulin causes fatty acid transport protein translocation and enhanced fatty acid uptake in adipocytes. (2002) (0)
- Anti-IRS-1 monoclonal antibody, 6G5, cross-reacts to IRS-2. (1996) (0)
- [Molecular genetics of NIDDM]. (1997) (0)
- [The 43rd Scientific Meeting: Perspectives of Internal Medicine; Genetic predisposition and related life-style underlying metabolic disorders 1. Preface]. (2016) (0)
- Association Between Plasma Triglycerides and HDL-Cholesterol and Microvascular Kidney Disease and Retinopathy in Type 2 Diabetes: A Global Case-Control Study in 13 Countries Running title: Sacks et al.; Plasma lipids in diabetic microvascular disease (2013) (0)
- [Control of lipid metabolism by insulin]. (2001) (0)
- AdipoRon: An anti-diabetes and anti-aging drug (2018) (0)
- BASIC—ALIMENTARY TRACT Loss of Adiponectin Promotes Intestinal Carcinogenesis in Min and Wild-type Mice (2011) (0)
- Preface (2010) (0)
- Tu-W22:3 Adiponectin modulates transcription factor activation by angiotensin II in smooth muscle cells (2006) (0)
- ESICON 2018 Abstracts (2018) (0)
- Long-term safety and effectiveness of linagliptin by baseline body mass index in Japanese patients with type 2 diabetes: a 3-year post-marketing surveillance study (2022) (0)
- Issue Information (2019) (0)
- Abstract 3850: The Ratio of Polyunsaturated to Saturated Fatty Acids in the Serum is a Strong Determinant of the Presence of Coronary Calcification Among US White and Japanese Men Aged 40 49 (2006) (0)
- In vivo molecular imaging revealed obese adipose tissue remodeling and malfunction in metabolic syndrome (2008) (0)
- Three-dimensional structure and receptor-recognition sites of bombyxin-II, an insulin-like brain-secretory peptide of the silkmoth (1999) (0)
- Diabetes mellitus : Advances of research and medical care. VI. Recent topics. 1. Mitochondrial gene abnormalities and diabetes mellitus. (1996) (0)
- 1697-P: NFIA Differentially Regulates Adipogenesis and Myogenesis through Distinct Molecular Pathways to Ensure Adipocyte Differentiation (2020) (0)
- Macrophages React to Postprandial Signals and Regulate the Response to Feeding through Akt-mTOR–Dependent Production of IL-10 (2018) (0)
- Dose-Response Relationship Between Severe Hypercholesterolemia and Body Mass Index in Healthy Young Adults. (2017) (0)
- [Hyponatremia induced by chlorpropamide]. (1983) (0)
- The adiponectin receptor: Physiology and pharmacology (2018) (0)
- KRÜPPEL-LIKE FACTOR 5 IS A KEY TRANSCRIPTION FACTOR OF ADIPOCYTE DIFFERENTIATION (2004) (0)
- Issue Information (2017) (0)
- 28 SNPs OF ADIPONECTIN RECEPTOR GENES IN PEDIATRIC DIABETES AND OBESTY (2003) (0)
- [Incretin related drugs]. (2010) (0)
- 2P-0328 Effect of egg intake on serum cholesterol, coronary and all cause mortality: NIPPON DATA80, 1980–1994 (2003) (0)
- Mo-P1:14 Influence of smoking habit on residual lifetime risk of cardiovascular diseases in Japanese representative population (2006) (0)
- [Glucose metabolism in adipose tissue]. (2002) (0)
- Glucagon-like peptide (GLP)-1 analogues as an add-on to insulin for adults with type 1 diabetes mellitus (2018) (0)
- Prevention of Worsening Diabetes through Behavioral Changes by an IoT-based Self-Monitoring System in Japan (PRISM-J): Study design and rationale for a multicenter, open-label, randomized parallel-group trial (2021) (0)
- Selection in Thymocyte Development β Phosphoinositide 3-Kinase Regulates Regulatory Subunit of Class IA α The p 85 Suzuki and (2007) (0)
- Controversies about the importance of increased waist circumference (0)
- Age‐Dependent Association Between Modifiable Risk Factors and Incident Cardiovascular Disease (2023) (0)
- Approach to the Pathogenesis of Non-Insulin-Dependent Diabetes Mellitus by Gene Targeting. (1997) (0)
- Obese adipose tissue remodeling, malfunctioning, and chronic inflammation visualized by in vivo molecular imaging (2009) (0)
- A randomized, placebo‐controlled trial to assess the efficacy and safety of sitagliptin in Japanese patients with type 2 diabetes and inadequate glycaemic control on ipragliflozin (2021) (0)
- [Intensive glucose control and cardiovascular outcomes in diabetes and impaired glucose tolerance]. (2011) (0)
- Abstract 19406: Amelioration of Streptozotocin-Induced Diabetic Hypertriglyceridemia in the Absence of Hormone-Sensitive Lipase (2016) (0)
- Abstract 18320: A Novel Tandem Duplication Containing a Noncoding Exon of the APOC2 Gene Causes Chylomicronemia With Markedly Reduced Levels of Plasma Apolipoprotein C-II (2016) (0)
- [Molecular structure related to the expression of insulin resistance and its evaluation]. (2004) (0)
- Transgenic Approach to Insulin Signaling (2002) (0)
- Osmotin is a Homolog of Human Adiponectin and Controls Apoptosis in Yeast Through a Homolog of Human Adiponectin Receptor (2004) (0)
- 2-B2-205 Developmental and functional impairment of B lymphocytes in mice lacking the p85a regulatory subunit of phosphatidylinositol-3 kinase (2008) (0)
- [HAIR-AN syndrome]. (1994) (0)
- [Anti-metabolic syndrome effects of candesartan]. (2009) (0)
- Willingness of Patients Prescribed Medications for Lifestyle-Related Diseases to Use Personal Health Records: Questionnaire Study (Preprint) (2019) (0)
- [Alcohol drinking habit and mortality]. (1997) (0)
- Cross-sectional associations between the types/amounts of beverages consumed and the glycemia status: The Japan Public Health Center-based Prospective Diabetes study (2022) (0)
- Daytime napping, daytime sleepiness and the risk of metabolic diseases: dose-response meta-analysis (2016) (0)
- Effect of once-weekly subcutaneous semaglutide 2.4 mg on weight- and health-related quality of life in an East Asian population: Patient-reported outcomes from the STEP 6 trial. (2023) (0)
- [Positioning of PROactive and its clinical application in Japan--a new direction in diabetes care discussed by diabetology and circulatory disease specialists: discussion]. (2006) (0)
- Issue Information (2017) (0)
- [Diabetes caused by glucokinase mutation]. (1998) (0)
- [Lipid disorder and atherosclerosis caused by smoking]. (2001) (0)
- Adiponectin and its receptors: A major role in type 2 diabetes and obesity-linked diseases (2016) (0)
- [Current trend in the care of diabetic patients: discussion]. (2000) (0)
- Issue Information (2017) (0)
- Efficacy and safety of fast-acting insulin aspart compared with insulin aspart in combination with insulin degludec in Japanese adults with type 1 diabetes: a subgroup analysis of the randomized onset 8 trial. (2020) (0)
- 607-P: Glycemic Metrics in Japanese Flash Glucose Monitoring Users by Diabetes Type and Therapy (2021) (0)
- Adipose Tissue Remodeling and Malfunctioning in Obesity Revealed by in vivo Molecular Imaging (2007) (0)
- Failure of compensatory beta-cell hyperplasia in response to insulin resistance plays a crucial role in the development of type 2 diabetes (2000) (0)
- [The use of new agents enhancing incretin effects for patients with diabetes in Japan]. (2011) (0)
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What Schools Are Affiliated With Takashi Kadowaki?
Takashi Kadowaki is affiliated with the following schools: