Takashi Kohno
#165,970
Most Influential Person Now
Researcher
Takashi Kohno's AcademicInfluence.com Rankings
Takashi Kohnocomputer-science Degrees
Computer Science
#9951
World Rank
#10439
Historical Rank
Computational Linguistics
#2476
World Rank
#2500
Historical Rank
Machine Learning
#4492
World Rank
#4542
Historical Rank
Artificial Intelligence
#4850
World Rank
#4913
Historical Rank
Download Badge
Computer Science
Takashi Kohno's Degrees
- PhD Computer Science University of Tokyo
- Masters Computer Science University of Tokyo
- Bachelors Computer Science University of Tokyo
Similar Degrees You Can Earn
Why Is Takashi Kohno Influential?
(Suggest an Edit or Addition)Takashi Kohno's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Comprehensive genomic profiles of small cell lung cancer (2015) (1397)
- KIF5B-RET fusions in lung adenocarcinoma (2012) (736)
- Circulating Exosomal microRNAs as Biomarkers of Colon Cancer (2014) (676)
- Identification of genes upregulated in ALK-positive and EGFR/KRAS/ALK-negative lung adenocarcinomas. (2012) (634)
- Genetic polymorphisms and alternative splicing of the hOGG1 gene, that is involved in the repair of 8-hydroxyguanine in damaged DNA (1998) (482)
- A second tumor necrosis factor receptor gene product can shed a naturally occurring tumor necrosis factor inhibitor. (1990) (298)
- Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia (2012) (277)
- Comprehensive Histologic Analysis of ALK-Rearranged Lung Carcinomas (2011) (269)
- Cloning of a human homolog of the yeast OGG1 gene that is involved in the repair of oxidative DNA damage (1997) (265)
- Prevalence and specificity of LKB1 genetic alterations in lung cancers (2007) (264)
- hOGG1 Ser326Cys polymorphism and lung cancer susceptibility. (1999) (250)
- Frequent BRG1/SMARCA4–inactivating mutations in human lung cancer cell lines (2008) (243)
- Vandetanib in patients with previously treated RET-rearranged advanced non-small-cell lung cancer (LURET): an open-label, multicentre phase 2 trial. (2017) (238)
- A synthetic lethality-based strategy to treat cancers harboring a genetic deficiency in the chromatin remodeling factor BRG1. (2013) (212)
- Beyond ALK-RET, ROS1 and other oncogene fusions in lung cancer. (2015) (206)
- The ACF1 complex is required for DNA double-strand break repair in human cells. (2010) (203)
- Histone acetylation by CBP and p300 at double-strand break sites facilitates SWI/SNF chromatin remodeling and the recruitment of non-homologous end joining factors. (2011) (194)
- Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases (2020) (191)
- The Association of MicroRNA Expression with Prognosis and Progression in Early-Stage, Non–Small Cell Lung Adenocarcinoma: A Retrospective Analysis of Three Cohorts (2011) (184)
- Frequent EGFR mutations in brain metastases of lung adenocarcinoma (2006) (179)
- A genome-wide association study identifies two new susceptibility loci for lung adenocarcinoma in the Japanese population (2012) (167)
- Druggable Oncogene Fusions in Invasive Mucinous Lung Adenocarcinoma (2014) (163)
- Targeting the Vulnerability of Glutathione Metabolism in ARID1A-Deficient Cancers. (2019) (161)
- Clinical utility of circulating tumor DNA for molecular assessment in pancreatic cancer (2015) (157)
- Inactivation of the PTEN/MMAC1/TEP1 gene in human lung cancers (1998) (154)
- Long-term expansion of alveolar stem cells derived from human iPS cells in organoids (2017) (151)
- ROS1-Rearranged Lung Cancer: A Clinicopathologic and Molecular Study of 15 Surgical Cases (2013) (150)
- Feasibility and utility of a panel testing for 114 cancer‐associated genes in a clinical setting: A hospital‐based study (2019) (149)
- Association of amino acid substitution polymorphisms in DNA repair genes TP53, POLI, REV1 and LIG4 with lung cancer risk (2005) (147)
- Meta- and pooled analysis of GSTT1 and lung cancer: a HuGE-GSEC review. (2006) (145)
- Gene aberrations for precision medicine against lung adenocarcinoma (2016) (145)
- Therapeutic Priority of the PI3K/AKT/mTOR Pathway in Small Cell Lung Cancers as Revealed by a Comprehensive Genomic Analysis (2014) (145)
- Structures of the extracellular domain of the type I tumor necrosis factor receptor. (1996) (144)
- Differential ability of polymorphic OGG1 proteins to suppress mutagenesis induced by 8-hydroxyguanine in human cell in vivo. (2004) (143)
- Molecular footprints of human lung cancer progression (2004) (143)
- MAX inactivation in small cell lung cancer disrupts MYC-SWI/SNF programs and is synthetic lethal with BRG1. (2014) (141)
- Histone acetylation by CBP and p300 at double-strand break sites facilitates SWI/SNF chromatin remodeling and the recruitment of non-homologous end joining factors (2011) (140)
- Contribution of the NQO1 and GSTT1 polymorphisms to lung adenocarcinoma susceptibility. (2002) (139)
- Clinicopathological and molecular characterization of SMARCA4-deficient thoracic sarcomas with comparison to potentially related entities (2017) (133)
- c-MET/Phospho-MET Protein Expression and MET Gene Copy Number in Non-small Cell Lung Carcinomas (2012) (133)
- Analysis of Heritability and Shared Heritability Based on Genome-Wide Association Studies for Thirteen Cancer Types. (2015) (133)
- Immunohistochemical detection of ROS1 is useful for identifying ROS1 rearrangements in lung cancers (2014) (129)
- RET-rearranged non-small-cell lung carcinoma: a clinicopathological and molecular analysis (2014) (128)
- The E3 ligase TTC3 facilitates ubiquitination and degradation of phosphorylated Akt. (2009) (128)
- Epidermal Growth Factor Receptor Tyrosine Kinase Defines Critical Prognostic Genes of Stage I Lung Adenocarcinoma (2012) (126)
- Familial gastric cancer: clinicopathological characteristics, RER phenotype and germline p53 and E-cadherin mutations. (1999) (126)
- Frequent allelic losses on chromosomes 2q, 18q, and 22q in advanced non-small cell lung carcinoma. (1994) (121)
- Clinicopathological significance of epigenetic inactivation of RASSF1A at 3p21.3 in stage I lung adenocarcinoma. (2002) (121)
- Somatic Genomics and Clinical Features of Lung Adenocarcinoma: A Retrospective Study (2016) (120)
- SWI/SNF factors required for cellular resistance to DNA damage include ARID1A and ARID1B and show interdependent protein stability. (2014) (119)
- Clinicopathological features of nonsmall cell lung carcinomas with BRAF mutations. (2014) (119)
- Constitutive activation of the Wnt signaling pathway by CTNNB1 (β‐catenin) mutations in a subset of human lung adenocarcinoma (2001) (118)
- Targeting p300 Addiction in CBP-Deficient Cancers Causes Synthetic Lethality by Apoptotic Cell Death due to Abrogation of MYC Expression. (2016) (116)
- Mutations and deletions of the CBP gene in human lung cancer. (2005) (116)
- How many tumor suppressor genes are involved in human lung carcinogenesis? (1999) (116)
- Infrequent Mutations of the hOGG1 Gene, That Is Involved in the Excision of 8‐Hydroxyguanine in Damaged DNA, in Human Gastric Cancer (1998) (115)
- A gene‐alteration profile of human lung cancer cell lines (2009) (112)
- RET fusion gene: Translation to personalized lung cancer therapy (2013) (112)
- Contribution of nicotine acetylcholine receptor polymorphisms to lung cancer risk in a smoking-independent manner in the Japanese. (2009) (109)
- Genome-wide identification of genes with amplification and/or fusion in small cell lung cancer (2013) (108)
- Deletion mapping of chromosome 3p in human uterine cervical cancer. (1993) (107)
- Regulatory Nexus of Synthesis and Degradation Deciphers Cellular Nrf2 Expression Levels (2013) (102)
- An Integrated Prognostic Classifier for Stage I Lung Adenocarcinoma Based on mRNA, microRNA, and DNA Methylation Biomarkers (2015) (99)
- Frequent co-localization of Cox-2 and laminin-5 gamma2 chain at the invasive front of early-stage lung adenocarcinomas. (2002) (98)
- Allelic imbalance and mutations of the PTEN gene in ovarian cancer (2000) (94)
- Clinicopathological significance of Fhit protein expression in stage I non-small cell lung carcinoma. (1998) (94)
- MYO18B, a candidate tumor suppressor gene at chromosome 22q12.1, deleted, mutated, and methylated in human lung cancer (2002) (94)
- Allelotype of neuroblastoma. (1995) (92)
- Correlation between the status of the p53 gene and survival in patients with stage I non-small cell lung carcinoma (1999) (92)
- Aberrant transcriptional regulations in cancers: genome, transcriptome and epigenome analysis of lung adenocarcinoma cell lines (2014) (91)
- A catalog of genes homozygously deleted in human lung cancer and the candidacy of PTPRD as a tumor suppressor gene (2010) (89)
- Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33. (2014) (88)
- Involvement of LKB1 in epithelial-mesenchymal transition (EMT) of human lung cancer cells. (2010) (86)
- Identification of stathmin as a novel substrate for p38 delta. (1998) (86)
- Association of the OGG1‐Ser326Cys polymorphism with lung adenocarcinoma risk (2006) (83)
- Genomic Amplification of CD274 (PD-L1) in Small-Cell Lung Cancer (2016) (83)
- Comparative allelotype of early and advanced stage non‐small cell lung carcinomas (1996) (83)
- Reduced Levels of ATF-2 Predispose Mice to Mammary Tumors (2006) (82)
- MYC Amplification as a Prognostic Marker of Early-Stage Lung Adenocarcinoma Identified by Whole Genome Copy Number Analysis (2010) (80)
- Identification of chromosome arm 9p as the most frequent target of homozygous deletions in lung cancer (2005) (80)
- Smoking and Genetic Risk Variation Across Populations of European, Asian, and African American Ancestry—A Meta‐Analysis of Chromosome 15q25 (2012) (77)
- Down-regulation of TCF8 is involved in the leukemogenesis of adult T-cell leukemia/lymphoma. (2008) (77)
- Allele frequencies of single nucleotide polymorphisms (SNPs) in 40 candidate genes for gene-environment studies on cancer: data from population-based Japanese random samples (2003) (77)
- Association of DNA repair gene polymorphisms with response to platinum-based doublet chemotherapy in patients with non-small-cell lung cancer. (2010) (76)
- Treatment of lung adenocarcinoma by molecular-targeted therapy and immunotherapy (2017) (75)
- Genetic basis for susceptibility to lung cancer: Recent progress and future directions. (2010) (74)
- Deletion map of chromosome 9 and p16 (CDKN2A) gene alterations in neuroblastoma. (1997) (74)
- Homozygous deletion at chromosome 2q33 in human small-cell lung carcinoma identified by arbitrarily primed PCR genomic fingerprinting. (1994) (74)
- Gene amplification-associated overexpression of the RNA editing enzyme ADAR1 enhances human lung tumorigenesis (2015) (74)
- Deletion mapping of chromosome 2 in human lung carcinoma (1996) (73)
- Molecular processes of chromosome 9p21 deletions in human cancers (2003) (71)
- Single-cell analysis of lung adenocarcinoma cell lines reveals diverse expression patterns of individual cells invoked by a molecular target drug treatment (2015) (71)
- Expression and clinical significance of genes frequently mutated in small cell lung cancers defined by whole exome/RNA sequencing. (2015) (69)
- Evaluation of a whole‐genome amplification method based on adaptor‐ligation PCR of randomly sheared genomic DNA (2003) (66)
- A secondary RET mutation in the activation loop conferring resistance to vandetanib (2018) (66)
- Utility of Assessing the Number of Mutated KRAS, CDKN2A, TP53, and SMAD4 Genes Using a Targeted Deep Sequencing Assay as a Prognostic Biomarker for Pancreatic Cancer (2017) (65)
- Genetic variants associated with longer telomere length are associated with increased lung cancer risk among never‐smoking women in Asia: a report from the female lung cancer consortium in Asia (2015) (64)
- Identification of a lung adenocarcinoma cell line with CCDC6‐RET fusion gene and the effect of RET inhibitors in vitro and in vivo (2013) (64)
- Homozygous deletion scanning of the lung cancer genome at a 100‐kb resolution (2007) (63)
- Association of CDKN2A (p16)/CDKN2B (p15) alterations and homozygous chromosome arm 9p deletions in human lung carcinoma (1998) (61)
- Significance of molecular classification of ependymomas: C11orf95-RELA fusion-negative supratentorial ependymomas are a heterogeneous group of tumors (2018) (60)
- HER2 gene mutations in non-small cell lung carcinomas: concurrence with Her2 gene amplification and Her2 protein expression and phosphorylation. (2015) (59)
- Identification of genes (SPON2 and C20orf2) differentially expressed between cancerous and noncancerous lung cells by mRNA differential display. (1999) (59)
- Identification of a functional SNP in the 3'UTR of CXCR2 that is associated with reduced risk of lung cancer. (2015) (59)
- Curcumin suppresses multiple DNA damage response pathways and has potency as a sensitizer to PARP inhibitor. (2013) (58)
- The cloning and characterization of a murine secretory leukocyte protease inhibitor cDNA. (1997) (58)
- Prevalent Involvement of Illegitimate V(D)J Recombination in Chromosome 9p21 Deletions in Lymphoid Leukemia* (2002) (57)
- Contribution of the TP53, OGG1, CHRNA3, and HLA-DQA1 Genes to the Risk for Lung Squamous Cell Carcinoma (2011) (57)
- Oncogenic Fusion Gene CD74-NRG1 Confers Cancer Stem Cell-like Properties in Lung Cancer through a IGF2 Autocrine/Paracrine Circuit. (2016) (57)
- Mouse Model for ROS1-Rearranged Lung Cancer (2013) (57)
- TSPAN12 is a critical factor for cancer–fibroblast cell contact-mediated cancer invasion (2014) (57)
- C646, a selective small molecule inhibitor of histone acetyltransferase p300, radiosensitizes lung cancer cells by enhancing mitotic catastrophe. (2014) (57)
- Reduced expression of MYO18B, a candidate tumor‐suppressor gene on chromosome arm 22q, in ovarian cancer (2004) (56)
- Bright-Field Dual-Color Chromogenic In Situ Hybridization for Diagnosing Echinoderm Microtubule-Associated Protein-Like 4-Anaplastic Lymphoma Kinase-Positive Lung Adenocarcinomas (2011) (56)
- Comprehensive analysis of p53 gene mutation characteristics in lung carcinoma with special reference to histological subtypes. (1999) (56)
- Homozygous deletion and reduced expression of the DOCK8 gene in human lung cancer. (2006) (55)
- Deficiency of Myo18B in mice results in embryonic lethality with cardiac myofibrillar aberrations (2008) (55)
- Inactivating mutations in SWI/SNF chromatin remodeling genes in human cancer. (2013) (54)
- Identification of genes whose expression is upregulated in lung adenocarcinoma cells in comparison with type II alveolar cells and bronchiolar epithelial cells in vivo (2004) (54)
- Garcinol, a histone acetyltransferase inhibitor, radiosensitizes cancer cells by inhibiting non-homologous end joining. (2012) (54)
- Association between GWAS-identified lung adenocarcinoma susceptibility loci and EGFR mutations in never-smoking Asian women, and comparison with findings from Western populations (2016) (53)
- Epigenetic clustering of lung adenocarcinomas based on DNA methylation profiles in adjacent lung tissue: Its correlation with smoking history and chronic obstructive pulmonary disease (2013) (53)
- Polynucleotide Kinase and Aprataxin-like Forkhead-associated Protein (PALF) Acts as Both a Single-stranded DNA Endonuclease and a Single-Stranded DNA 3′ Exonuclease and Can Participate in DNA End Joining in a Biochemical System* (2011) (53)
- The usefulness of mutation-specific antibodies in detecting epidermal growth factor receptor mutations and in predicting response to tyrosine kinase inhibitor therapy in lung adenocarcinoma. (2011) (52)
- Identification and Characterization of a New Phospholipase C-like Protein, PLC-L2 (1999) (51)
- Role of Copper Transport Protein Antioxidant 1 in Angiotensin II–Induced Hypertension: A Key Regulator of Extracellular Superoxide Dismutase (2012) (51)
- KAT6B Is a Tumor Suppressor Histone H3 Lysine 23 Acetyltransferase Undergoing Genomic Loss in Small Cell Lung Cancer. (2015) (51)
- Sequencing and phasing cancer mutations in lung cancers using a long-read portable sequencer (2017) (51)
- Individuals susceptible to lung adenocarcinoma defined by combined HLA-DQA1 and TERT genotypes. (2010) (50)
- CBP and p300 Histone Acetyltransferases Contribute to Homologous Recombination by Transcriptionally Activating the BRCA1 and RAD51 Genes (2012) (49)
- Combination of protein coding and noncoding gene expression as a robust prognostic classifier in stage I lung adenocarcinoma. (2013) (49)
- Growth suppression by MYC inhibition in small cell lung cancer cells with TP53 and RB1 inactivation (2016) (48)
- Identification of a 428-kb homozygously deleted region disrupting the SEZ6L gene at 22q12.1 in a lung cancer cell line (2000) (48)
- Frequent EGFR mutations in noninvasive bronchioloalveolar carcinoma (2006) (46)
- Frequent microsatellite instability and BAX mutations in T cell acute lymphoblastic leukemia cell lines. (2000) (46)
- Epidermal growth factor receptor mutation is associated with longer local control after definitive chemoradiotherapy in patients with stage III nonsquamous non-small-cell lung cancer. (2015) (46)
- OGG1 protein suppresses G:C-->T:A mutation in a shuttle vector containing 8-hydroxyguanine in human cells. (2001) (45)
- Homozygous deletion and frequent allelic loss of the 21q11.1‐q21.1 region including the ANA gene in human lung carcinoma (1998) (45)
- The intratumoral distribution influences the prognostic impact of CD68- and CD204-positive macrophages in non-small cell lung cancer. (2018) (44)
- Molecular processes of chromosome 9p21 deletions causing inactivation of the p16 tumor suppressor gene in human cancer: deduction from structural analysis of breakpoints for deletions. (2006) (44)
- Identification of a novel phospholipase C family gene at chromosome 2q33 that is homozygously deleted in human small cell lung carcinoma. (1995) (44)
- Molecular Mechanisms Underlying Oncogenic RET Fusion in Lung Adenocarcinoma (2014) (43)
- Picoliter-Droplet Digital Polymerase Chain Reaction-Based Analysis of Cell-Free Plasma DNA to Assess EGFR Mutations in Lung Adenocarcinoma That Confer Resistance to Tyrosine-Kinase Inhibitors. (2016) (43)
- Association of variations in HLA class II and other loci with susceptibility to EGFR-mutated lung adenocarcinoma (2016) (43)
- A novel tumor suppressor locus on chromosome 18q involved in the development of human lung cancer. (1998) (42)
- MYCL is a target of a BET bromodomain inhibitor, JQ1, on growth suppression efficacy in small cell lung cancer cells (2016) (42)
- A mouse model of KIF5B-RET fusion-dependent lung tumorigenesis. (2014) (41)
- Unbalanced translocation, a major chromosome alteration causing loss of heterozygosity in human lung cancer (2008) (41)
- hOGG 1 Ser 326 Cys Polymorphism and Lung Cancer Susceptibility 1 (1999) (41)
- Somatic mutations and single nucleotide polymorphisms of base excision repair genes involved in the repair of 8-hydroxyguanine in damaged DNA. (2001) (41)
- Frequent BRAF or EGFR Mutations in Ciliated Muconodular Papillary Tumors of the Lung (2016) (40)
- Infrequent mutations of the transforming growth factor beta-type II receptor gene at chromosome 3p22 in human lung cancers with chromosome 3p deletions. (1997) (40)
- Evaluation and application of RNA-Seq by MinION (2018) (40)
- The low expression of miR-451 predicts a worse prognosis in non-small cell lung cancer cases (2017) (39)
- Genetic and epigenetic alterations of the candidate tumor‐suppressor gene MYO18B, on chromosome arm 22q, in colorectal cancer (2005) (39)
- Body mass index (BMI), BMI change, and overall survival in small cell and non-small cell lung cancer patients: a pooled analysis of the International Lung Cancer Consortium. (2019) (39)
- The genomic and epigenomic landscape in thymic carcinoma (2017) (39)
- Meta-analysis of genome-wide association studies identifies multiple lung cancer susceptibility loci in never-smoking Asian women. (2016) (38)
- GRWD1 negatively regulates p53 via the RPL11–MDM2 pathway and promotes tumorigenesis (2017) (38)
- Development of lung adenocarcinomas with exclusive dependence on oncogene fusions. (2015) (38)
- Carbon-Ion Beam Irradiation Kills X-Ray-Resistant p53-Null Cancer Cells by Inducing Mitotic Catastrophe (2014) (37)
- Whole genome comparison of allelic imbalance between noninvasive and invasive small-sized lung adenocarcinomas. (2009) (35)
- Association of habitual smoking and drinking with single nucleotide polymorphism (SNP) in 40 candidate genes: data from random population-based Japanese samples (2005) (35)
- IQGAP1 links PDGF receptor-β signal to focal adhesions involved in vascular smooth muscle cell migration: role in neointimal formation after vascular injury. (2013) (35)
- Comprehensive screening of target molecules by next-generation sequencing in patients with malignant solid tumors: guiding entry into phase I clinical trials (2016) (34)
- LPP inhibits collective cell migration during lung cancer dissemination (2016) (34)
- Involvement of Ku80 in microhomology-mediated end joining for DNA double-strand breaks in vivo. (2007) (34)
- A Three-microRNA Signature Predicts Responses to Platinum-Based Doublet Chemotherapy in Patients with Lung Adenocarcinoma (2014) (34)
- Genetic alterations and expression of the protein phosphatase 1 genes in human cancers. (2001) (33)
- Molecular dynamics simulation-guided drug sensitivity prediction for lung cancer with rare EGFR mutations (2019) (33)
- DNA Methylation Profiles at Precancerous Stages Associated with Recurrence of Lung Adenocarcinoma (2013) (33)
- Chromatin-regulating proteins as targets for cancer therapy (2014) (33)
- Expansion of Cancer Risk Profile for BRCA1 and BRCA2 Pathogenic Variants (2022) (33)
- Differential expression of the LAMB3 and LAMC2 genes between small cell and non-small cell lung carcinomas. (2000) (33)
- Clinical practice guidance for next-generation sequencing in cancer diagnosis and treatment (edition 2.1) (2020) (32)
- REToma: a cancer subtype with a shared driver oncogene. (2019) (32)
- Allelotype and replication error phenotype of small cell lung carcinoma. (1997) (32)
- Association of p16 Homozygous Deletions with Clinicopathologic Characteristics and EGFR/KRAS/p53 Mutations in Lung Adenocarcinoma (2008) (32)
- Implementation of “clinical sequencing” in cancer genome medicine in Japan (2018) (32)
- Identification of CpG islands hypermethylated in human lung cancer by the arbitrarily primed-PCR method (1998) (31)
- Prevalence of human papillomavirus 16/18/33 infection and p53 mutation in lung adenocarcinoma (2010) (31)
- N-cadherin expression is a potential survival mechanism of gefitinib-resistant lung cancer cells. (2011) (31)
- Correlation between histone acetylation and expression of the MYO18B gene in human lung cancer cells (2004) (31)
- Clonal and Parallel Evolution of Primary Lung Cancers and Their Metastases Revealed by Molecular Dissection of Cancer Cells (2007) (30)
- Association of polymorphisms in the MTH1 gene with small cell lung carcinoma risk. (2006) (30)
- Frequent amplification of receptor tyrosine kinase genes in well-differentiated/ dedifferentiated liposarcoma (2017) (30)
- Possible involvement of LKB1-AMPK signaling in non-homologous end joining (2014) (30)
- TSPAN2 is involved in cell invasion and motility during lung cancer progression. (2014) (30)
- Alterations of the PPP1R3 gene in human cancer. (1999) (29)
- The EGFR mutation status affects the relative biological effectiveness of carbon-ion beams in non-small cell lung carcinoma cells (2015) (29)
- Identification of tumor markers and differentiation markers for molecular diagnosis of lung adenocarcinoma (2006) (29)
- Mitotic catastrophe is a putative mechanism underlying the weak correlation between sensitivity to carbon ions and cisplatin (2017) (28)
- Expression of the OGG1-type 1a (nuclear form) protein in cancerous and non-cancerous human cells. (2000) (28)
- Prognostic significance of allelic imbalances on chromosome 9p in stage I non-small cell lung carcinoma. (1999) (28)
- Determination of tumor necrosis factor binding protein disulfide structure: deviation of the fourth domain structure from the TNFR/NGFR family cysteine-rich region signature. (1997) (27)
- Cancer Susceptibility Polymorphism of p53 at Codon 72 Affects Phosphorylation and Degradation of p53 Protein* (2011) (27)
- Vaginal Transmission of Cancer from Mothers with Cervical Cancer to Infants. (2021) (27)
- Identification of candidate responders for anti-PD-L1/PD-1 immunotherapy, Rova-T therapy, or EZH2 inhibitory therapy in small-cell lung cancer. (2017) (26)
- Two regions of homozygous deletion clusters at chromosome band 9p21 in human lung cancer (2000) (26)
- Suppressive activities of OGG1 and MYH proteins against G:C to T:A mutations caused by 8-hydroxyguanine but not by benzo[a]pyrene diol epoxide in human cells in vivo. (2003) (26)
- Pathogenetic and biologic significance of TP14ARF alterations in nonsmall cell lung carcinoma. (2003) (26)
- Mutation and expression of the p51 gene in human lung cancer. (1999) (26)
- Body Mass Index (BMI), BMI Change, and Overall Survival in Patients With SCLC and NSCLC: A Pooled Analysis of the International Lung Cancer Consortium (2019) (25)
- Analysis of Heritability and Shared Heritability Based on Genome-Wide Association Studies for 13 Cancer Types (2015) (24)
- Localization of a human lung adenocarcinoma susceptibility locus, possibly syntenic to the mouse Pas1 locus, in the vicinity of the D12S1034 locus on chromosome 12p11.2-p12.1. (2002) (24)
- An Oncogenic ALK Fusion and an RRAS Mutation in KRAS Mutation-Negative Pancreatic Ductal Adenocarcinoma. (2017) (23)
- Identification and characterization of a new phospholipase C-like protein, PLC-L(2). (1999) (23)
- Microsatellite instability in lymphoid leukemia and lymphoma cell lines but not in myeloid leukemia cell lines (1999) (23)
- The Expression of Four Genes as a Prognostic Classifier for Stage I Lung Adenocarcinoma in 12 Independent Cohorts (2014) (22)
- Novel Role of Copper Transport Protein Antioxidant-1 in Neointimal Formation After Vascular Injury (2013) (22)
- Essential Factors for Incompatible DNA End Joining at Chromosomal DNA Double Strand Breaks In Vivo (2011) (22)
- Clonality and heterogeneity of pulmonary blastoma from the viewpoint of genetic alterations: a case report. (2007) (22)
- Spinal cord astroblastoma with an EWSR1‐BEND2 fusion classified as a high‐grade neuroepithelial tumour with MN1 alteration (2019) (21)
- Erratum: Gene amplification-associated overexpression of the RNA editing enzyme ADAR1 enhances human lung tumorigenesis (2016) (21)
- Association of KRAS polymorphisms with risk for lung adenocarcinoma accompanied by atypical adenomatous hyperplasias. (2008) (21)
- A Two‐Gene Prognostic Classifier for Early‐Stage Lung Squamous Cell Carcinoma in Multiple Large‐Scale and Geographically Diverse Cohorts (2017) (20)
- Infrequent mutations of the activating transcription factor-2 gene in human lung cancer, neuroblastoma and breast cancer. (2002) (20)
- Multiplex Diagnosis of Oncogenic Fusion and MET Exon Skipping by Molecular Counting Using Formalin‐Fixed Paraffin Embedded Lung Adenocarcinoma Tissues (2016) (20)
- Profiling of actionable gene alterations in ovarian cancer by targeted deep sequencing. (2015) (20)
- Development of targeted therapy and immunotherapy for treatment of small cell lung cancer (2018) (20)
- Deleterious Pulmonary Surfactant System Gene Mutations in Lung Adenocarcinomas Associated With Usual Interstitial Pneumonia. (2018) (19)
- Prognostic implication of PTPRH hypomethylation in non-small cell lung cancer (2015) (19)
- Genetic alterations responsible for metastatic phenotypes of lung cancer cells (2004) (19)
- Genomic alterations in STK11 can predict clinical outcomes in cervical cancer patients. (2019) (19)
- Germline Mutations of the PTEN/MMAC1 Gene in Japanese Patients with Cowden Disease (1998) (19)
- A phase II open-label single-arm study of vandetanib in patients with advanced RET-rearranged non-small cell lung cancer (NSCLC): Luret study. (2016) (19)
- NEK9-dependent proliferation of cancer cells lacking functional p53 (2014) (19)
- A computational tool to detect DNA alterations tailored to formalin-fixed paraffin-embedded samples in cancer clinical sequencing (2018) (19)
- Contribution of germline mutations to PARK2 gene inactivation in lung adenocarcinoma (2012) (19)
- Physical and transcriptional map of a 311-kb segment of chromosome 18q21, a candidate lung tumor suppressor locus. (2001) (18)
- Detection of amplified genomic sequences in human small-cell lung carcinoma cells by arbitrarily primed-PCR genomic fingerprinting (1996) (18)
- Absence of hSNF5/INI1 mutation in human lung cancer. (2000) (18)
- CD74-ROS1 fusion transcripts in resected non-small cell lung carcinoma. (2013) (18)
- Molecular Process Producing Oncogene Fusion in Lung Cancer Cells by Illegitimate Repair of DNA Double-Strand Breaks (2015) (18)
- SMARCA4 deficiency-associated heterochromatin induces intrinsic DNA replication stress and susceptibility to ATR inhibition in lung adenocarcinoma (2020) (18)
- Therapeutic preferability of gemcitabine for ARID1A-deficient ovarian clear cell carcinoma. (2019) (18)
- Long-term prognosis of patients with resected adenocarcinoma in situ and minimally invasive adenocarcinoma of the lung. (2021) (17)
- Circulating cell-free plasma tumour DNA shows a higher incidence of EGFR mutations in patients with extrathoracic disease progression (2018) (17)
- Long-read sequencing for non-small-cell lung cancer genomes (2020) (17)
- The relationship between body-mass index and overall survival in non-small cell lung cancer by sex, smoking status, and race: A pooled analysis of 20,937 International lung Cancer consortium (ILCCO) patients. (2020) (16)
- Combinatory use of distinct single-cell RNA-seq analytical platforms reveals the heterogeneous transcriptome response (2018) (16)
- Suppression of chemically induced and spontaneously occurring oxidative mutagenesis by three alleles of human OGG1 gene encoding 8-hydroxyguanine DNA glycosylase. (2004) (16)
- Phenotypic alterations of small cell lung carcinoma induced by different levels of wild-type p53 expression (1998) (16)
- High-grade glioneuronal tumor with an ARHGEF2–NTRK1 fusion gene (2019) (16)
- Treatment Strategies for ARID1A-Deficient Ovarian Clear Cell Carcinoma (2021) (16)
- Impact of KRAS mutation on response and outcome of patients with stage III non-squamous non-small cell lung cancer (2015) (16)
- Emergence and Targeting of Acquired and Hereditary Resistance to Multikinase RET Inhibition in Patients With RET-Altered Cancer (2019) (15)
- Tuberculosis infection and lung adenocarcinoma: Mendelian randomization and pathway analysis of genome-wide association study data from never-smoking Asian women. (2019) (15)
- Update on Epidemiology, Diagnosis, and Biomarkers in Gastroenteropancreatic Neuroendocrine Neoplasms (2022) (15)
- The mechanism of the glycosylase reaction with hOGG1 base-excision repair enzyme: concerted effect of Lys249 and Asp268 during excision of 8-oxoguanine (2017) (14)
- Identification of a novel KLC1–ROS1 fusion in a case of pediatric low-grade localized glioma (2018) (14)
- Somatic mutations and genetic polymorphisms of the PPP1R3 gene in patients with several types of cancers (2000) (14)
- Evaluating Clinical Genome Sequence Analysis by Watson for Genomics (2018) (13)
- Alterations in expression of E2F‐1 and E2F‐responsive genes by RB, p53 and p21 Sdi1/WAF1/Cip1 expression (2001) (13)
- Whole genome sequencing to identify predictive markers for the risk of drug-induced interstitial lung disease (2019) (13)
- Final survival results for the LURET phase II study of vandetanib in previously treated patients with RET-rearranged advanced non-small cell lung cancer. (2021) (13)
- Frequent chromosome 8q gains in human small cell lung carcinoma detected by arbitrarily primed-PCR genomic fingerprinting. (2000) (13)
- Genes involved in development and differentiation are commonly methylated in cancers derived from multiple organs: a single-institutional methylome analysis using 1007 tissue specimens (2016) (13)
- Ordering of human chromosome 3p markers by radiation hybrid mapping. (1992) (12)
- Breakpoint junction of interstitial homozygous deletion at chromosome 2q33 in a small cell lung carcinoma. (1996) (12)
- Precision medicine for ovarian clear cell carcinoma based on gene alterations (2020) (12)
- Characterization of cancer omics and drug perturbations in panels of lung cancer cells (2019) (12)
- Identification and characterization of families with aggregation of lung cancer. (1998) (12)
- Association of CYP19A1 polymorphisms with risks for atypical adenomatous hyperplasia and bronchioloalveolar carcinoma in the lungs. (2010) (12)
- Efficacy of glutathione inhibitors for the treatment of ARID1A-deficient diffuse-type gastric cancers. (2019) (11)
- Mutation and expression of the DCC gene in human lung cancer. (2000) (11)
- Genomic structure and chromosomal localization of the mouse Ogg1 gene that is involved in the repair of 8-hydroxyguanine in DNA damage (2009) (11)
- Copper transporter ATP7A interacts with IQGAP1, a Rac1 binding scaffolding protein: role in PDGF-induced VSMC migration and vascular remodeling. (2018) (11)
- Significantly mutated genes and regulatory pathways in SCLC-a meta-analysis. (2017) (11)
- Medical treatment involving investigational drugs and genetic profile of thymic carcinoma. (2016) (11)
- A Nucleolar Stress–Specific p53–miR-101 Molecular Circuit Functions as an Intrinsic Tumor-Suppressor Network (2018) (10)
- Long read sequencing reveals a novel class of structural aberrations in cancers: identification and characterization of cancerous local amplifications (2019) (10)
- Chromosome 3p deletion in a renal cell carcinoma cell line established from a patient with von Hippel-Lindau disease. (1993) (10)
- Identification of D19S246 as a novel lung adenocarcinoma susceptibility locus by genome survey with 10-cM resolution microsatellite markers. (2003) (10)
- Activity and Immune Correlates of Programmed Deaht-1 Blockade Therapy in Patients With Advanced Large Cell Neuroendocrine Carcinoma. (2021) (9)
- A full genome scan for gastric cancer (2005) (9)
- Genetic Determinants of Lung Cancer Prognosis in Never Smokers: A Pooled Analysis in the International Lung Cancer Consortium (2020) (9)
- MUSASHI‐2 confers resistance to third‐generation EGFR‐tyrosine kinase inhibitor osimertinib in lung adenocarcinoma (2021) (9)
- The first case of SMARCB1 (INI1) - deficient squamous cell carcinoma of the pleura: a case report (2018) (9)
- Gene aberration profile of tumors of adolescent and young adult females (2017) (8)
- Comparative Analysis of Genetic Alterations, HPV-Status, and PD-L1 Expression in Neuroendocrine Carcinomas of the Cervix (2021) (8)
- Poly(ADP-ribose) polymerase-1 gene in human tumor cell lines: Its expression and structural alteration (2004) (8)
- Abstract 5721: Garcinol, a histone acetyltransferase inhibitor, radiosensitizes cancer cells by inhibiting non-homologous end joining (2012) (8)
- Impact of ALK Inhibitors in Patients With ALK-Rearranged Nonlung Solid Tumors (2021) (8)
- Primary adenocarcinoma of the trachea revealing a mucinous bronchial gland cell origin. (2018) (7)
- Growth suppression of non-small cell lung carcinoma cells by the introduction of the p16(INK4A) gene. (1997) (7)
- BRAF V600E mutation is a potential therapeutic target for a small subset of synovial sarcoma (2020) (7)
- Genomic profiling in advanced stage non-small-cell lung cancer patients with platinum-based chemotherapy identifies germline variants with prognostic value in SMYD2. (2018) (7)
- ARID1A deficiency in EBV-positive gastric cancer is partially regulated by EBV-encoded miRNAs, but not by DNA promotor hypermethylation. (2020) (6)
- DNA hypermethylation of the ZNF132 gene participates in the clinicopathological aggressiveness of ‘pan-negative’-type lung adenocarcinomas (2020) (6)
- Identification of potential regulatory mutations using multi-omics analysis and haplotyping of lung adenocarcinoma cell lines (2018) (6)
- HSP90 inhibition overcomes EGFR amplification‐induced resistance to third‐generation EGFR‐TKIs (2021) (6)
- Common TDP1 Polymorphisms in Relation to Survival among Small Cell Lung Cancer Patients: A Multicenter Study from the International Lung Cancer Consortium (2017) (6)
- Contribution of the NQO 1 and GSTT 1 Polymorphisms to Lung Adenocarcinoma Susceptibility 1 (2002) (5)
- Comparative Fiber-FISH Reveals What Happened at the Integration Site of the Transfected Plasmid DNA (2013) (5)
- IQGAP 1 links PDGF receptor-signal to focal adhesions involved in vascular smooth muscle cell migration : role in neointimal formation after vascular injury (2013) (5)
- A new nationwide genomic screening system in Japan for the development of targeted therapies against advanced non-small lung cancers with rare driver mutations. (2014) (5)
- Differential Immune-Related Microenvironment Determines PD-1/PD-L1 Blockade Efficacy in Advanced Non-Small Cell Lung Cancer Patients. (2021) (5)
- Feasibility and clinical utility of comprehensive genomic profiling of hematological malignancies (2022) (5)
- Phasing analysis of lung cancer genomes using a long read sequencer (2022) (5)
- Genome-Wide Chromatin Analysis of FFPE Tissues Using a Dual-Arm Robot with Clinical Potential (2021) (5)
- Probing the chromosome 9p21 region susceptible to DNA double-strand breaks in human cells in vivo by restriction enzyme transfer (2005) (5)
- KAT 6 B Is a Tumor Suppressor Histone H 3 Lysine 23 Acetyltransferase UndergoingGenomic Loss in Small Cell Lung Cancer (2015) (5)
- Optimal Targeting of HER 2 – PI 3 K Signaling in Breast Cancer : Mechanistic Insights and Clinical Implications (2013) (4)
- Proposal for a synthetic lethality therapy using the paralog dependence of cancer cells--response. (2014) (4)
- Genetic defects in cancer cells and cancer prone families. (1996) (4)
- Garcinol, a Histone Acetyltransferase Inhibitor, Radiosensitizes Cancer Cells by Inhibiting Nonhomologous End Joining (2012) (4)
- Subependymal giant cell astrocytoma harboring a PRRC2B‐ALK fusion: A case report (2019) (4)
- Rapid assessment of two major repair activities against DNA double-strand breaks in vertebrate cells. (2006) (4)
- C-CAT: The National Datacenter for Cancer Genomic Medicine in Japan (2022) (4)
- Corrigendum to: Frequent microsatellite instability and BAX mutations in T cell acute lymphoblastic leukemia cell lines Leukemia Research 24 (2000), 255-262. (2001) (4)
- Lung Adenocarcinoma Mouse Models Based on Orthotopic Transplantation of Syngeneic Tumor-Initiating Cells Expressing EpCAM, SCA-1, and Ly6d (2020) (4)
- Electronic microarray technique for detection of nine base substitutions including single-nucleotide polymorphisms in the human OGG1 gene. (2004) (4)
- The Lung Cancer Genomic Screening Project for Individualized Medicine in Japan (LC-SCRUM-Japan): Screening for RET and ROS1 fusions in advanced EGFR mutation-negative nonsquamous lung cancer and development of molecular targeted therapy. (2014) (3)
- [Tumor suppressor genes]. (1993) (3)
- Study protocol for NCCH1908 (UPFRONT-trial): a prospective clinical trial to evaluate the feasibility and utility of comprehensive genomic profiling prior to the initial systemic treatment in advanced solid tumour patients. (2021) (3)
- Clonal Hematopoiesis From Next Generation Sequencing of Plasma From a Patient With Lung Adenocarcinoma: A Case Report (2020) (3)
- Nationwide genomic screening network for the development of novel targeted therapies in advanced non-small cell lung cancer (LC-SCRUM-Japan). (2015) (3)
- Distribution of genetic alterations in high-risk early-stage cervical cancer patients treated with postoperative radiation therapy (2021) (3)
- Upregulation of FGF9 in Lung Adenocarcinoma Transdifferentiation to Small Cell Lung Cancer (2021) (3)
- Smoking and Genetic Risk Variation Across Populations of European, Asian, and African American Ancestry—A Meta‐Analysis of Chromosome 15q25 (2012) (3)
- Targeted-sequencing in rare cancers and the impact on patient treatment. (2019) (3)
- CD 74-ROS 1 fusion transcripts in resected non-small cell lung carcinoma (2013) (2)
- Endometrial cancer arising after complete remission of uterine malignant lymphoma: A case report and mutation analysis (2019) (2)
- Gene Specific-Primer Extension Preamplification (GS-PEP), a simple method to increase the copy number of a gene prior to PCR amplification (2002) (2)
- Gene Amplification-Associated Overexpression of the Selenoprotein tRNA Enzyme TRIT1 Confers Sensitivity to Arsenic Trioxide in Small-Cell Lung Cancer (2021) (2)
- Genomic Ampli fi cation of CD 274 ( PD-L 1 ) in Small-Cell Lung Cancer (2017) (2)
- Histone Acetyltransferases (HATs) Involved in Non-Homologous End Joining as a Target for Radiosensitization (2013) (2)
- Prediction of tissue-of-origin of early stage cancers using serum miRNomes (2022) (2)
- An Overview of Genetic Polymorphism and Lung Cancer Risk (2016) (2)
- PCR fingerprinting for detection of deleted or amplified sequences in human cancer. (1998) (2)
- Next-Generation Sequencer Analysis of Pulmonary Pleomorphic Carcinoma With a CD74-ROS1 Fusion Successfully Treated With Crizotinib. (2019) (2)
- Heterogeneity of ARID1A expression in gastric cancer may affect patient survival and therapeutic efficacy. (2020) (2)
- [Genetic factors involved in cancer susceptibility]. (2002) (2)
- Genetic Polymorphisms Underlying Lung Cancer Susceptibility and Therapeutic Response (2012) (1)
- Long-Term Prognosis and Prognostic Indicators of Stage IA Lung Adenocarcinoma (2022) (1)
- Abstract A61: MiR-101 as a molecular switch for sequential activation of p53-dependent G1 and G2 checkpoints in response to ribosomal stress (2013) (1)
- Advances in targeted therapy and immunotherapy for treatment of lung cancer (2016) (1)
- 1333PDetectability of RET fusions by amplicon-based next generation sequencing in nationwide lung cancer genomic screening project: LC-SCRUM-Japan (2017) (1)
- Alterations of the PPP1R3 gene in hematological malignancies. (2000) (1)
- P3.03-010 Identification of Mechanisms of Drug Resistance in RET-Rearranged Lung Cancer (2017) (1)
- Simple prediction model for homologous recombination deficiency in breast cancers in adolescents and young adults (2020) (1)
- [Wnt signaling abnormalities in human lung cancer]. (2002) (1)
- Radiopathologic correlation of collision lung cancer with ground-glass opacity (2018) (1)
- Automated and rapid system for detection of ALK rearrangement genes in non-small cell lung cancer based on a Quenching Probe method (2016) (1)
- [Challenge of gene-based personalized lung cancer medicine]. (2015) (1)
- Single-Cell Transcriptome Profiling Reveals Intratumoral Heterogeneity and Molecular Features of Ductal Carcinoma In Situ. (2022) (1)
- Clinical impact of genetic alterations of CTNNB1 in patients with grade 3 endometrial endometrioid carcinoma (2022) (1)
- Comparison of clinicopathological and genomic profiles in anal squamous cell carcinoma between Japanese and Caucasian cohorts (2023) (1)
- Gene expression classifier for prognosis of early-stage squamous cell carcinoma of the lung (2016) (1)
- 689PGENE MUTATION PROFILE OF PANCREATIC CANCER OBTAINED USING TARGETED DEEP SEQUENCING AND ITS ASSOCIATION WITH PROGNOSIS. (2014) (1)
- O2-9-5GENE MUTATION PROFILE OF PANCREATIC CANCER IN JAPANESE PATIENTS AND ITS ASSOCIATION WITH PROGNOSIS (2014) (1)
- Development of nationwide genomic screening project (LC-SCRUM-Japan) contributing to the establishment of precision medicine in Japan. (2016) (1)
- [Differences between EGFR Exon 19 Deletion and Exon 21 L858R Point Mutation, Frequently Detected EGFR Mutations in Patients with Non-Small Cell Lung Cancer, from a Molecular Biology Viewpoint]. (2021) (1)
- Abstract B65: Curcumin, a novel inhibitor of ATR-CHK1 pathway, suppresses homologous recombination and DNA damage checkpoint and enhances the sensitivity to PARP inhibitors. (2011) (1)
- A functional SNP in MRPL43 modulates lung cancer susceptibility and survival through alternative splicing of its isoforms (2016) (1)
- Abstract B93: Gene fusions detected by whole transcriptome sequencing of lung adenocarcinoma. (2011) (0)
- Analysis of circulating cell-free DNA in plasma shows a higher detection rate of EGFR mutations in patients with extrathoracic disease progression (2016) (0)
- [Lung cancer genomics and its application to prevention, diagnosis and treatment of lung cancer]. (2010) (0)
- Abstract 1432: Precision lung cancer medicine based on information on cancer and the host genomes (2017) (0)
- 482OClinical impact of a pre-screening system using comprehensive genomic profiling to guide phase I trial registry in patients with advanced solid tumors (2015) (0)
- Abstract 2248: CommonTDP1polymorphisms in relation to survival among small cell lung cancer patients in a multicenter study from the International Lung Cancer Consortium (2017) (0)
- Upregulation of endothelial ICAM‐1 expression by plasma from somatic mutations and genetic polymorphisms of the PPPR1R3 gene in patients with several types of cancers (2000) (0)
- ASO Visual Abstract: Long-Term Prognosis and Prognostic Indicators of Stage IA Lung Adenocarcinoma (2022) (0)
- PL01.06 Molecular Epidemiology of Asian Lung Cancer (2021) (0)
- Drug response prediction using deep neural network trained by adaptive resampling of histopathological images (2022) (0)
- Studies Combination of Protein Coding and Noncoding Gene Expression as a Robust Prognostic Classi fi er in Stage I Lung Adenocarcinoma (2013) (0)
- Abstract A29: Targeting p300 addiction in CBP-deficient cancers causes synthetic lethality by apoptotic cell death due to abrogation of MYC expression (2017) (0)
- Identification of inflamed-phenotype of small cell lung cancer leading to the efficacy of anti-PD-L1 antibody and chemotherapy. (2022) (0)
- Impact of the presence of EGFR mutation on definitive chemoradiotherapy in patients with locally advanced non-small cell lung cancer: Pattern of relapses and survival analyses in 145 patients. (2017) (0)
- Molecular Genetics of Thymic Carcinoma (2019) (0)
- The CAncer Genomic Test Standardized Format : A Unified File Format to Summarize Genomic Aberrations (2022) (0)
- Degradation of p 53 Protein at Codon 72 Affects Phosphorylation and Cancer Susceptibility Polymorphism of p 53 Molecular Bases of Disease (2011) (0)
- Abstract 2468: Gene aberrations for precision medicine against lung adenocarcinoma (2017) (0)
- Abstract 2568: Meta-analysis of genome-wide association studies identifies multiple lung cancer susceptibility loci in never-smoking Asian women (2016) (0)
- O1-5-1Detectability of druggable gene fusions by amplicon-based next generation sequencing in LC-SCRUM-Japan (2016) (0)
- Evaluation of DNA Damage Response After Carbon-Ion Beam Irradiation in p53-Mutant Cancer Cells (2014) (0)
- Novel Calcium-Binding Ablating Mutations Induce Constitutive RET Activity and Drive Tumorigenesis (2022) (0)
- A computational tool to detect DNA alterations tailored to formalin-fixed paraffin-embedded samples in cancer clinical sequencing (2018) (0)
- [Fusion Genes in Cancer-Toward Treatment from a Pan-Cancer Perspective]. (2022) (0)
- Thanking All Peer Reviewers. (2015) (0)
- Abstract LB-132: Critical prognostic genes for stage I lung cancer are identified from normal growth factor-regulated gene network by overcoming cancer heterogeneity (2010) (0)
- Long-term culture of human iPS cell-derived alveolar stem cells harboring cellular heterogeneity in organoids (2017) (0)
- Impact of genomic alterations and HPV genotypes on clinical outcomes of Japanese patients with locally advanced cervical cancer (2019) (0)
- Additional file 1: of Comprehensive screening of target molecules by next-generation sequencing in patients with malignant solid tumors: guiding entry into phase I clinical trials (2016) (0)
- 230 Feasibility study of targeted sequencing-based molecular prescreening of patients for Phase I clinical trials. Trial of Oncopanel for Introduction into Clinical Study Phase 1 (TOPICS-1) (2015) (0)
- An in silico approach to treating “the right patient with the right drug at the right dose at the right time” (2015) (0)
- Oncogenic point mutation of RET receptor tyrosine kinase (2018) (0)
- Discovery of DS-9300: A Highly Potent, Selective, and Once-Daily Oral EP300/CBP Histone Acetyltransferase Inhibitor. (2022) (0)
- Detectability of druggable gene fusions by amplicon-based next generation sequencing in nationwide lung cancer genomic screening project (LC-SCRUM-Japan) (2016) (0)
- Whole-genome Sequencing-based Lung Cancer Precision Medicine in Japan (2022) (0)
- Promise of vandetanib, a FDA-approved RET kinase inhibitor, for the treatment of RET fusion-positive lung adenocarcinoma (2016) (0)
- RET and other genes: therapeutic targets in lung adenocarcinoma (2014) (0)
- ISY-27-1Molecular target therapy of AYA-generation lung cancer based on druggable gene alterations (2016) (0)
- Additional file 8: Table S2. of Comprehensive screening of target molecules by next-generation sequencing in patients with malignant solid tumors: guiding entry into phase I clinical trials (2016) (0)
- NEW MUTAGENICITY TESTS USING HUMAN GENES ENCODING DNA REPAIR ENZYMES. (1998) (0)
- Identification of a novel therapeutic target in driver-negative non-small cell lung cancer. (2018) (0)
- Abstract 4264: Clinical targeted sequencing from FFPE tumor tissue samples for early-phase clinical trials at the National Cancer Center of Japan (2015) (0)
- Additional file 5: Table S7. of Comprehensive screening of target molecules by next-generation sequencing in patients with malignant solid tumors: guiding entry into phase I clinical trials (2016) (0)
- Abstract B29: Feasibility of amplicon sequencing using a pan-cancer gene panel with pre-treatment biopsy samples of (Japanese) patients with advanced solid tumors: Analyses of Biopsy Samples for Cancer Genomics (ABC) study. (2013) (0)
- A secondary RET mutation in the activation loop conferring resistance to vandetanib (2018) (0)
- 463 Multiplex detection of 17 kinds of oncogenic fusion and aberrant transcripts in formalin-fixed, paraffin embedded tissues of lung adenocarcinoma by molecular counting (2015) (0)
- P3.02-035 Mutational Signatures and Their Association with Clinicopathological Features in Lung Adenocarcinoma of Smokers (2017) (0)
- 359. Combined ,Effect of Hyperthermia with Radiation for Uteine Cervical Cancer (1986) (0)
- Mitochondrial fusion factor OPA1 sustains gefitinib-resistance in lung adenocarcinoma cells (2021) (0)
- Liquid biopsy for the detection of resistance mutations to ROS1 and RET inhibitors in non-small lung cancers: A case series study. (2022) (0)
- Accounting for EGFR mutations in epidemiological analyses of non-small cell lung cancers: Examples based on the International Lung Cancer Consortium data. (2022) (0)
- Abstract 5715: Epigenomic profiling identifies distinct neuroendocrine subtypes in lung cancer with neuroendocrine differentiation (2022) (0)
- Abstract 13647: Copper Transport Protein Antioxidant-1 Plays an Important Role in Neointmal Formation in Response to Vascular Injury by Regulating Vascular Smooth Muscle Cell Migration (2011) (0)
- Inhibition of the mitochondria-shaping protein Opa1 restores sensitivity to Gefitinib in a lung adenocarcinomaresistant cell line (2023) (0)
- Abstract 1311: Inter- and intra-tumor heterogeneity of genetic and immune profiles in hereditary clear cell renal cell carcinoma (2020) (0)
- Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases (2020) (0)
- Abstract 2094: Correaltions between genome-wide DNA methylation profiles and genomic driver aberrations during multistage lung adenocaricinogenesis (2021) (0)
- Abstract A47: Epigenetic regulation of microRNAs in early stage lung adenocarcinoma (2013) (0)
- Predictive model for the preoperative assessment and prognostic modeling of lymph node metastasis in endometrial cancer (2022) (0)
- Somatic mutations and genetic polymorphisms of the PPPRIR3 gene in patients with several types of cancers (2000) (0)
- ISS2-2-1Nationwide genomic screening network for the development of targeted therapies in NSCLC (LC-SCRUM-Japan) (2015) (0)
- Abstract A1-55: Combination of a three-microRNA signature and TP53 genotype predicts responses to platinum-based doublet chemotherapy in patients with lung adenocarcinoma (2015) (0)
- T-cell leukemia/lymphoma Down-regulation of TCF8 is involved in the leukemogenesis of adult (2013) (0)
- The evolution of cancer genomic medicine in Japan and the role of the National Cancer Center Japan. (2023) (0)
- 1210PIMPACT OF KRAS MUTATION ON THE RESPONSE AND PROGNOSIS OF PATIENTS WITH STAGE III NON-SQUAMOUS NON-SMALL CELL LUNG CANCER. (2014) (0)
- Identification of Synthetic Lethal Target in CBP Knockout Cells (2017) (0)
- Clinicopathological characteristics and molecular analysis of lung cancer associated with ciliated muconodular papillary tumor/bronchiolar adenoma. (2023) (0)
- Title Carbon-Ion Beam Irradiation Kills X-Ray-Resistant p 53-Null Cancer Cellsby Inducing Mitotic Catastrophe (2017) (0)
- Abstract 5378: Genes involved in development and differentiation are commonly methylated in cancers derived from multiple organs: A single-institutional methylome analysis using 1007 tissue specimens (2017) (0)
- Rare FGFR fusion genes and subgrouping patients with a poor prognosis using RNA-based classification in cervical cancer (2023) (0)
- Combinatory use of distinct single-cell RNA-seq analytical platforms reveals the heterogeneous transcriptome response (2018) (0)
- Abstract 918: A secondaryRETmutation allosterically conferring resistance to vandetanib (2018) (0)
- Abstract LB-99: EGF receptor tyrosine kinase defines critical prognostic genes of stage IA lung adenocarcinoma (2012) (0)
- Abstract 1214: RET fusion gene: translation to the therapy of lung adenocarcinoma. (2013) (0)
- Utility of molecular subtypes and genetic alterations for evaluating clinical outcomes in 1029 patients with endometrial cancer (2023) (0)
- Genetic Susceptibility to Lung Adenocarcinoma (2014) (0)
- Abstract A32: RET fusion gene: Translation to personalized lung cancer therapy. (2014) (0)
- Abstract 18886: IQGAP1, a Rac1 Binding Scaffold Protein, Interacts with Copper Transporter ATP7A: Role in ATP7A-mediated PDGF-induced VSMC Migration and Neointimal Formation (2010) (0)
- Abstract B35: The expression of four genes as a prognostic classifier for stage I lung adenocarcinoma in 12 independent cohorts. (2014) (0)
- Fine-tuning of p53-dependent nucleolus stress response by miR-101 (2016) (0)
- Single-cell analysis of lung adenocarcinoma cell lines reveals diverse expression patterns of individual cells invoked by a molecular target drug treatment (2015) (0)
- Comments to the letter by Edmond S. K. Ma et al. (2007) (0)
- Recommendations related to the analytical equivalence assessment of gene panel testing (2022) (0)
- Tokuda Akihiro Tomida Shinya Toyokuni Hitoshi Tsuda Shoichiro Tsugane Tatsuhiko Tsunoda Heiichiro Udono Koji Ueda Yoshimasa Uehara Hiroo Ueno Kazuo Umezawa Toshikazu Ushijima Toshihiko Wakabayashi Kenji Wakai Tetsuro Watabe (2016) (0)
- Dicer is essential for the survival and proliferation of retinal progenitor cells (0)
- Identification of D 19 S 246 as a Novel Lung Adenocarcinoma Susceptibility Locus by Genome Survey with 10-cM Resolution Microsatellite Markers 1 (2003) (0)
- Abstract C109: Association of TP53 gene polymorphism with response to platinum-based doublet chemotherapy in non-small cell lung cancer patients. (2011) (0)
- Circulating tumor DNA molecular profiling in rare cancer patients from the MASTER KEY Project. (2019) (0)
- Identification of potential regulatory mutations using multi-omics analysis and haplotyping of lung adenocarcinoma cell lines (2018) (0)
- Electronic Microarray Technique for Detection of Nine Base Substitutions including Single-nucleotide Poly- Morphisms in the Human Ogg1 Gene, Zhilong Gong, 1# (2004) (0)
- Additional file 3: Table S5. of Comprehensive screening of target molecules by next-generation sequencing in patients with malignant solid tumors: guiding entry into phase I clinical trials (2016) (0)
- Abstract 5247: Predominance of EGFR mutations responsible for resistance to tyrosine kinase inhibitors among tumor DNAs assessed by picoliter droplet digital PCR analysis of cell-free plasma DNAs (2015) (0)
- 1307PA NATIONWIDE GENOMIC SCREENING SYSTEM IN JAPAN FOR THE DEVELOPMENT OF MOLECULAR TARGETED THERAPIES AGAINST NON-SMALL CELL LUNG CANCERS WITH RARE DRIVER MUTATIONS. (2014) (0)
- Abstract 15685: Copper Transport Protein Antioxidant-1 Mediates Vascular Remodeling via Promoting Macrophage Infiltration and Copper- and Rac1-dependent Vascular Migration (2012) (0)
- MA15.03 Exploring Digital Pathology-Based Morphological Biomarkers for a Better Patients’ Selection to the Immune Checkpoint Inhibitor of Lung Cancer (2019) (0)
- Abstract 15729: Copper Transporter ATP7A Limits Vascular Inflammation and Aortic Aneurysm Development (2015) (0)
- ES 04.01 Novel Targetable Oncogenes in Lung Cancer (2017) (0)
- Inside the USCAP Journals (2022) (0)
- 1227PDNATIONWIDE GENOMIC SCREENING FOR RET FUSION IN ADVANCED EGFR MUTATION-NEGATIVE NON-SQUAMOUS LUNG CANCER AND DEVELOPMENT OF MOLECULAR TARGETED THERAPY IN JAPAN: LC-SCRUM-JAPAN. (2014) (0)
- P3.02-041 EGFR Amplification Mediates Resistance to TAS121, A Third-Generation EGFR-TKI, in EGFR T790M-Positive Non-Small Cell Lung Cancer (2017) (0)
- Abstract 4669: Druggable oncogene fusions in lung invasive mucinous adenocarcinoma (2015) (0)
- Additional file 7: Table S4. of Comprehensive screening of target molecules by next-generation sequencing in patients with malignant solid tumors: guiding entry into phase I clinical trials (2016) (0)
- Assessment of homologous recombination deficiency phenotype in breast cancers in adolescents and young adults in the clinical setting (2019) (0)
- Abstract 3551: Simple vs. comprehensive prediction models of homologous recombination deficiency based on mutational and clinical features in three independent breast cancer datasets (2020) (0)
- Comprehensive screening of target molecules by next-generation sequencing in patients with malignant solid tumors: guiding entry into phase I clinical trials (2016) (0)
- Additional file 2: Table S1. of Comprehensive screening of target molecules by next-generation sequencing in patients with malignant solid tumors: guiding entry into phase I clinical trials (2016) (0)
- 3043 Clinicopathological features of patients with ROS1-rearranged advanced non-small cell lung cancer: LC-SCRUM-Japan (2015) (0)
- Mechanisms of Lung Carcinogenesis Associated with Interstitial Pneumonia (2019) (0)
- [AP-PCR genomic fingerprinting]. (1996) (0)
- Comparisons between mouse and human studies will help the prevention, diagnosis, and treatment of the deadliest type of lung cancer. (2015) (0)
- Abstract 1597: C646, a selective small molecule inhibitor of p300, radiosensitizes cancer cells through enhancement of mitotic catastrophe. (2013) (0)
- Abstract 5364: DNA methylation profiles at precancerous stage cluster lung adenocarcinomas into subclusters associated with carcinogenetic pathway, clinicopathological aggressiveness and patient outcome. (2013) (0)
- Thanking All Peer Reviewers. (2019) (0)
- Clinical Studies Combination of Protein Coding and Noncoding Gene Expression as a Robust Prognostic Classi fi er in Stage I Lung Adenocarcinoma (2013) (0)
This paper list is powered by the following services:
What Schools Are Affiliated With Takashi Kohno?
Takashi Kohno is affiliated with the following schools:
