Takashi Okamoto
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Chemistry Biology
Takashi Okamoto's Degrees
- PhD Biochemistry University of Tokyo
- Masters Chemistry University of Tokyo
- Bachelors Chemistry University of Tokyo
Why Is Takashi Okamoto Influential?
(Suggest an Edit or Addition)Takashi Okamoto's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Co-purification and Direct Interaction of Ras with Caveolin, an Integral Membrane Protein of Caveolae Microdomains (1996) (1031)
- Molecular Cloning of Caveolin-3, a Novel Member of the Caveolin Gene Family Expressed Predominantly in Muscle (*) (1996) (761)
- Expression of Caveolin-3 in Skeletal, Cardiac, and Smooth Muscle Cells (1996) (700)
- Identification, sequence, and expression of caveolin-2 defines a caveolin gene family. (1996) (588)
- Caveolin‐mediated regulation of signaling along the p42/44 MAP kinase cascade in vivo (1998) (410)
- Involvement of the transcription factor NF-kappaB in tubular morphogenesis of human microvascular endothelial cells by oxidative stress (1996) (288)
- Tat competes with CIITA for the binding to P-TEFb and blocks the expression of MHC class II genes in HIV infection. (2000) (266)
- Identification of a Gs activator region of the β2-adrenergic receptor that is autoregulated via protein kinase A-dependent phosphorylation (1991) (257)
- A simple structure encodes G protein-activating function of the IGF-II/mannose 6-phosphate receptor (1990) (256)
- Cellular levels of thioredoxin associated with drug sensitivity to cisplatin, mitomycin C, doxorubicin, and etoposide. (1995) (252)
- G Protein-Mediated Neuronal DNA Fragmentation Induced by Familial Alzheimer's Disease-Associated Mutants of APP (1996) (219)
- Involvement of Histone H3 Lysine 9 (H3K9) Methyltransferase G9a in the Maintenance of HIV-1 Latency and Its Reactivation by BIX01294* (2010) (219)
- Flotillins/Cavatellins Are Differentially Expressed in Cells and Tissues and Form a Hetero-oligomeric Complex with Caveolins in Vivo (1999) (216)
- The Polycystic Kidney Disease-1 Protein, Polycystin-1, Binds and Activates Heterotrimeric G-Proteinsin Vitro (1998) (200)
- Antioxidants modulate acute solar ultraviolet radiation-induced NF-kappa-B activation in a human keratinocyte cell line. (1999) (190)
- Detection of G protein-activator regions in M4 subtype muscarinic, cholinergic, and alpha 2-adrenergic receptors based upon characteristics in primary structure. (1992) (189)
- Involvement of the Interaction between p21 and Proliferating Cell Nuclear Antigen for the Maintenance of G2/M Arrest after DNA Damage* (2001) (189)
- Transcription factor Y-box binding protein 1 binds preferentially to cisplatin-modified DNA and interacts with proliferating cell nuclear antigen. (1999) (187)
- c-Myc recruits P-TEFb for transcription, cellular proliferation and apoptosis (2003) (185)
- Affinity-purification and characterization of caveolins from the brain: Differential expression of caveolin-1, -2, and -3 in brain endothelial and astroglial cell types (1998) (183)
- Expression of caveolin-1 and -2 in differentiating PC12 cells and dorsal root ganglion neurons: caveolin-2 is up-regulated in response to cell injury. (1998) (180)
- Molecular genetics of the caveolin gene family: implications for human cancers, diabetes, Alzheimer disease, and muscular dystrophy. (1998) (179)
- Akt-Mediated Survival of Oligodendrocytes Induced by Neuregulins (2000) (175)
- The role of p38 mitogen‐activated protein kinase in IL‐6 and IL‐8 production from the TNF‐α‐ or IL‐1β‐stimulated rheumatoid synovial fibroblasts (2000) (166)
- The NF-κB Activation in Lymphotoxin β Receptor Signaling Depends on the Phosphorylation of p65 at Serine 536* (2003) (161)
- Identification of a Novel Inhibitor of Nuclear Factor-κB, RelA-associated Inhibitor* (1999) (157)
- Inhibition of the DNA‐binding activity of NF‐κB by gold compounds in vitro (1995) (151)
- Involvement of the Pro-oncoprotein TLS (Translocated in Liposarcoma) in Nuclear Factor-κB p65-mediated Transcription as a Coactivator* (2001) (150)
- The polycystic kidney disease-1 protein, polycystin-1, binds and activates heterotrimeric G-proteins in vitro. (1998) (147)
- Transcriptional Repression of Human Immunodeficiency Virus Type 1 by AP-4* (2006) (146)
- Smad3 is acetylated by p300/CBP to regulate its transactivation activity (2007) (144)
- Direct interaction of p53 with the Y-box binding protein, YB-1: a mechanism for regulation of human gene expression (2000) (138)
- Inhibition of the NF-κB transcriptional activity by protein kinase A (2002) (137)
- Induction of cytokines and ICAM-1 by proinflammatory cytokines in primary rheumatoid synovial fibroblasts and inhibition by N-acetyl-L-cysteine and aspirin. (1996) (136)
- Human thioredoxin/adult T cell leukemia-derived factor activates the enhancer binding protein of human immunodeficiency virus type 1 by thiol redox control mechanism. (1992) (134)
- Involvement of thioredoxin in rheumatoid arthritis: its costimulatory roles in the TNF-alpha-induced production of IL-6 and IL-8 from cultured synovial fibroblasts. (1999) (134)
- Direct control of exocytosis by receptor‐mediated activation of the heterotrimeric GTPases Gi and G(o) or by the expression of their active G alpha subunits. (1995) (129)
- Reactivation of Latent HIV-1 Infection by the Periodontopathic Bacterium Porphyromonas gingivalis Involves Histone Modification1 (2009) (125)
- Demonstration of virus-specific transcriptional activator(s) in cells infected with HTLV-III by an in vitro cell-free system (1986) (124)
- Induction of ADF/TRX by oxidative stress in keratinocytes and lymphoid cells. (1995) (123)
- Molecular and cellular biology of caveolae paradoxes and plasticities. (1997) (122)
- Y box-binding protein-1 binds preferentially to single-stranded nucleic acids and exhibits 3'-->5' exonuclease activity. (2001) (119)
- Characterization of long terminal repeat sequences of HTLV-III. (1985) (118)
- Expression of V642 APP mutant causes cellular apoptosis as Alzheimer trait‐linked phenotype. (1996) (118)
- Induction of Notch signaling by tumor necrosis factor in rheumatoid synovial fibroblasts (2003) (117)
- Sensitization of cancer cells to DNA damage-induced cell death by specific cell cycle G2 checkpoint abrogation. (1999) (112)
- Expression of the thioredoxin-thioredoxin reductase system in the inflamed joints of patients with rheumatoid arthritis. (1999) (111)
- Evidence for regulation of NF-kappaB by poly(ADP-ribose) polymerase. (2000) (111)
- Augmentation of human immunodeficiency virus type 1 gene expression by tumor necrosis factor alpha. (1989) (106)
- NF-κB subunit p65 binds to 53BP2 and inhibits cell death induced by 53BP2 (1999) (101)
- Distinctive regulation of the functional linkage between the human cation-independent mannose 6-phosphate receptor and GTP-binding proteins by insulin-like growth factor II and mannose 6-phosphate. (1990) (100)
- Inhibition of Nuclear Factor-κB-mediated Transcription by Association with the Amino-terminal Enhancer of Split, a Groucho-related Protein Lacking WD40 Repeats* (2000) (97)
- G protein βγ complex‐mediated apoptosis by familial Alzheimer's disease mutant of APP (1997) (96)
- A potential role of activated NF-κB in the pathogenesis of euthyroid sick syndrome (2000) (94)
- TRAF6‐NF‐κB pathway is essential for interleukin‐1‐induced TLR2 expression and its functional response to TLR2 ligand in murine hepatocytes (2003) (94)
- NF-κB Signaling and Carcinogenesis (2007) (91)
- Effects of anti-nuclear factor kappa B reagents in blocking adhesion of human cancer cells to vascular endothelial cells. (1995) (90)
- The NF-kappa B activation in lymphotoxin beta receptor signaling depends on the phosphorylation of p65 at serine 536. (2003) (88)
- Selective inhibition of NF‐κB activation by the flavonoid hepatoprotector silymarin in HepG2 (1998) (87)
- Decreased Expression of Hippocampal Cholinergic Neurostimulating Peptide Precursor Protein mRNA in the Hippocampus in Alzheimer Disease (2002) (86)
- RNA helicase A interacts with nuclear factor kappaB p65 and functions as a transcriptional coactivator. (2004) (85)
- Caveolin-3 Upregulation Activates β-Secretase–Mediated Cleavage of the Amyloid Precursor Protein in Alzheimer’s Disease (1999) (83)
- Insulin-Like Growth Factor I (IGF-I) Protects Cells from Apoptosis by Alzheimer's V642I Mutant Amyloid Precursor Protein through IGF-I Receptor in an IGF-Binding Protein-Sensitive Manner (2001) (78)
- AKIP1 Enhances NF-κB-dependent Gene Expression by Promoting the Nuclear Retention and Phosphorylation of p65* (2008) (75)
- Regulation of NF-kappa B and disease control: identification of a novel serine kinase and thioredoxin as effectors for signal transduction pathway for NF-kappa B activation. (1997) (74)
- A-kinase-interacting Protein 1 (AKIP1) Acts as a Molecular Determinant of PKA in NF-κB Signaling (2010) (73)
- Cdc25C interacts with PCNA at G2/M transition (2002) (71)
- Inhibition of the NF-kappaB transcriptional activity by protein kinase A. (2002) (70)
- Prevention of the Ultraviolet B-Mediated Skin Photoaging by a Nuclear Factor κB Inhibitor, Parthenolide (2005) (70)
- NF-kappaB and rheumatic diseases. (2006) (68)
- Inhibition of the SDF-1alpha-CXCR4 axis by the CXCR4 antagonist AMD3100 suppresses the migration of cultured cells from ATL patients and murine lymphoblastoid cells from HTLV-I Tax transgenic mice. (2009) (67)
- Binding of Tat protein to TAR region of human immunodeficiency virus type 1 blocks TAR-mediated activation of (2'-5')oligoadenylate synthetase. (1990) (66)
- Inhibition of IL-6 and IL-8 induction from cultured rheumatoid synovial fibroblasts by treatment with aurothioglucose. (1999) (66)
- Intrinsic signaling function of APP as a novel target of three V642 mutations linked to familial Alzheimer's disease. (1996) (65)
- Identification of Highly Selective and Potent Histone Deacetylase 3 Inhibitors Using Click Chemistry-Based Combinatorial Fragment Assembly (2013) (65)
- Pancreatitis-Associated Protein-III Is a Novel Macrophage Chemoattractant Implicated in Nerve Regeneration (2006) (64)
- Amino acids 356–372 constitute a Gi‐activator sequence of the α2‐adrenergic receptor and have a Phe substitute in the G protein‐activator sequence motif (1992) (64)
- Reactivation of latent HIV-1 by a wide variety of butyric acid-producing bacteria (2012) (63)
- Growth Inhibition of Multiple Myeloma Cells by a Novel IκB Kinase Inhibitor (2005) (61)
- Protecting Skin Photoaging by NF-κB Inhibitor (2010) (61)
- NF-kappa B signaling and carcinogenesis. (2007) (58)
- Gene expression profile analysis of rheumatoid synovial fibroblast cultures revealing the overexpression of genes responsible for tumor-like growth of rheumatoid synovium. (2002) (57)
- Aberrant overexpression of 53BP2 mRNA in lung cancer cell lines (2000) (57)
- Enhancer profiling identifies critical cancer genes and characterizes cell identity in adult T-cell leukemia. (2017) (57)
- Presence of NF‐κB‐like and IκB‐like immunoreactivities in postsynaptic densities (1997) (56)
- Functional characterization of Tat protein from human immunodeficiency virus. Evidence that Tat links viral RNAs to nuclear matrix. (1990) (56)
- RelA-Associated Inhibitor Blocks Transcription of Human Immunodeficiency Virus Type 1 by Inhibiting NF-κB and Sp1 Actions (2002) (55)
- Selective inhibition of NF-kappaB activation by the flavonoid hepatoprotector silymarin in HepG2. Evidence for different activating pathways. (1998) (54)
- The role of p38 mitogen-activated protein kinase in IL-6 and IL-8 production from the TNF-alpha- or IL-1beta-stimulated rheumatoid synovial fibroblasts. (2000) (53)
- NF-κB p65 transactivation domain is involved in the NF-κB-inducing kinase pathway (2003) (53)
- The 1999 Moyer award. Burn injury induces skeletal muscle apoptosis and the activation of caspase pathways in rats. (1999) (53)
- Identification of a cis-regulatory element involved in accumulation of human T-cell leukemia virus type II genomic mRNA (1988) (52)
- Magnolia ovovata extract and its active component magnolol prevent skin photoaging via inhibition of nuclear factor kappaB. (2007) (52)
- Induction of cell death in adult T-cell leukemia cells by a novel IκB kinase inhibitor (2006) (50)
- Transcriptional activation from the long-terminal repeat of human immunodeficiency virus in vitro. (1990) (50)
- Phosphoinositide 3‐kinase inhibitor (wortmannin) inhibits pancreatic cancer cell motility and migration induced by hyaluronan in vitro and peritoneal metastasis in vivo (2009) (49)
- Inhibition of the DNA-binding activity of NF-kappa B by gold compounds in vitro. (1995) (49)
- Analysis of stimulation-G protein subunit coupling by using active insulin-like growth factor II receptor peptide. (1991) (49)
- Proteolytic processing of nuclear factor κB by calpain in vitro (1996) (48)
- Molecular cloning of cDNA for human poly(ADP-ribose) polymerase and expression of its gene during HL-60 cell differentiation. (1987) (45)
- Identification of the nuclear localization signal of mouse DNA primase: nuclear transport of p46 subunit is facilitated by interaction with p54 subunit. (1996) (45)
- α‐Lipoic acid blocks HIV‐1 LTR‐dependent expression of hygromycin resistance in THP‐1 stable transformants (1996) (43)
- Low pH enhances Sp1 DNA binding activity and interaction with TBP. (2003) (43)
- Global optimization using a synchronization of multiple search Points autonomously driven by a chaotic dynamic model (2008) (43)
- A potential role of activated NF-kappa B in the pathogenesis of euthyroid sick syndrome. (2000) (42)
- Tissue-specific expression of multiple gamma-glutamyl transpeptidase mRNAs in rat epithelia. (1991) (42)
- Measurement of GTPγS binding to specific G proteins in membranes using G‐protein antibodies (1992) (41)
- Negative transactivation of cAMP response element by familial Alzheimer's mutants of APP. (1996) (41)
- Inhibition of human immunodeficiency virus type 1 replication by a bioavailable serine/threonine kinase inhibitor, fasudil hydrochloride. (1998) (41)
- Inhibition of the RNA-dependent transactivation and replication of human immunodeficiency virus type 1 by a fluoroquinoline derivative K-37. (2000) (40)
- NF-kappaB subunit p65 binds to 53BP2 and inhibits cell death induced by 53BP2. (1999) (40)
- Anti-rheumatic compound aurothioglucose inhibits tumor necrosis factor-alpha-induced HIV-1 replication in latently infected OM10.1 and Ach2 cells. (1999) (39)
- Evaluation of online miRNA resources for biomedical applications (2012) (39)
- Inhibition of Human Immunodeficiency Virus Type 1 Replication in Latently Infected Cells by a Novel IκB Kinase Inhibitor (2006) (38)
- Proteome analyses of the growth inhibitory effects of NCH-51, a novel histone deacetylase inhibitor, on lymphoid malignant cells (2007) (38)
- Insulin-like growth factor-II/mannose 6-phosphate receptor is incapable of activating GTP-binding proteins in response to mannose 6-phosphate, but capable in response to insulin-like growth factor-II. (1990) (37)
- 53BP2 induces apoptosis through the mitochondrial death pathway (2005) (37)
- RING Finger Protein AO7 Supports NF-κB-mediated Transcription by Interacting with the Transactivation Domain of the p65 Subunit* (2003) (36)
- Analysis of the Association of Proteins with Membranes (2000) (35)
- Microbial interaction of periodontopathic bacterium Porphyromonas gingivalis and HIV-possible causal link of periodontal diseases to AIDS progression-. (2012) (35)
- Participation of platelet‐activating factor in the lipopolysaccharide‐induced liver injury in partially hepatectomized rats (1999) (34)
- Functional characterization of the rat gamma-glutamyl transpeptidase promoter that is expressed and regulated in the liver and hepatoma cells. (1994) (34)
- Growth inhibition of multiple myeloma cells by a novel IkappaB kinase inhibitor. (2005) (33)
- Evidence that de novo protein synthesis is dispensable for anti-apoptotic effects of NF-κB (2000) (32)
- Apoptosis in neurodegenerative diseases. (1997) (32)
- Novel histone deacetylase inhibitor NCH‐51 activates latent HIV‐1 gene expression (2011) (31)
- Regulation of transmembrane signal transduction of insulin-like growth factor II by competence type growth factors or viral ras p21. (1991) (30)
- Estrogen stimulates transcription of human immunodeficiency virus type 1 (HIV-1). (2006) (30)
- Aberrant MHC class II expression in mouse joints leads to arthritis with extraarticular manifestations similar to rheumatoid arthritis (2006) (30)
- Positive correlation between sialyl Lewis X expression and pathologic findings in renal cell carcinoma. (2005) (29)
- G protein betagamma complex-mediated apoptosis by familial Alzheimer's disease mutant of APP. (1997) (28)
- Transcriptional control of HIV replication by multiple modulators and their implication for a novel antiviral therapy. (2012) (27)
- Reciprocal modulation of transcriptional activities between HIV-1 Tat and MHC class II transactivator CIITA. (2000) (27)
- GTP‐binding protein‐activator sequences in the insulin receptor (1993) (27)
- Low molecular weight lignin suppresses activation of NF-κB and HIV-1 promoter (2008) (27)
- The interaction with Sp1 and reduction in the activity of histone deacetylase 1 are critical for the constitutive gene expression of IL‐1α in human melanoma cells (2008) (27)
- Expression of 53BP2 and ASPP2 proteins from TP53BP2 gene by alternative splicing. (2004) (26)
- Induction of OGG1 Gene Expression by HIV-1 Tat* (2005) (26)
- Rapid Serodiagnosis of Mycobacterium avium‐intracellulare Complex Infection by ELISA with Cord Factor (Trehalose 6, 6′‐Dimycolate), and Serotyping Using the Glycopeptidolipid Antigen (1998) (26)
- 3‐Methylcholanthrene Activates Human Immunodeficiency Virus Type 1 Replication via Aryl Hydrocarbon Receptor (2003) (25)
- Expression of the rat gamma-glutamyl transpeptidase gene from a specific promoter in the small intestine and in hepatoma cells. (1994) (25)
- A Single-Nucleotide Synonymous Mutation in the gag Gene Controlling Human Immunodeficiency Virus Type 1 Virion Production (2006) (24)
- Identification of a second promoter which drives the expression of gamma-glutamyl transpeptidase in rat kidney and epididymis. (1992) (23)
- Protecting skin photoaging by NF-kappaB inhibitor. (2010) (23)
- Evidence for regulation of NF-κ B by poly ( ADP-ribose ) polymerase (23)
- Distinct mode of G protein activation due to single residue substitution of active IGF-II receptor peptide Arg2410-Lys2423: evidence for stimulation acceptor region other than C-terminus of Gi alpha. (1991) (23)
- NF-kappa B p65 transactivation domain is involved in the NF-kappa B-inducing kinase pathway. (2003) (22)
- Feed-forward Regulatory Loop Driven by IRF4 and NF-κB in Adult T-cell Leukemia/Lymphoma. (2020) (22)
- Calpain is involved in the HIV replication from the latently infected OM10.1 cells. (2003) (21)
- HIV Tat/P-TEFb Interaction: A Potential Target for Novel Anti-HIV Therapies (2018) (21)
- Identification of a novel growth-promoting factor with a wide target cell spectrum from various tumor cells as catalase. (1996) (21)
- Inhibition of human immunodeficiency virus type 1 replication by blocking IkappaB kinase with noraristeromycin. (2008) (20)
- Inhibition of the 53BP2S‐mediated apoptosis by nuclear factor κB and Bcl‐2 family proteins (2005) (20)
- Conversion of G-protein specificity of insulin-like growth factor II/mannose 6-phosphate receptor by exchanging of a short region with beta-adrenergic receptor. (1993) (20)
- MicroRNAs in HIV-1 infection: an integration of viral and cellular interaction at the genomic level (2012) (19)
- Inhibition of Human Immunodeficiency Virus Type 1 Replication by Combination of Transcription Inhibitor K-12 and Other Antiretroviral Agents in Acutely and Chronically Infected Cells (1999) (19)
- Measurement of GTP gamma S binding to specific G proteins in membranes using G-protein antibodies. (1992) (19)
- Global optimization using a multipoint type quasi-chaotic optimization method (2013) (19)
- Preferential expression and immunogenicity of HIV-1 Tat fusion protein expressed in tomato plant (2010) (19)
- Guanine nucleotide-binding protein interacting but unstimulating sequence located in insulin-like growth factor II receptor. Its autoinhibitory characteristics and structural determinants. (1991) (19)
- Inhibition of human immunodeficiency virus type 1 replication in latently infected cells by a novel IkappaB kinase inhibitor. (2006) (18)
- Dominant negative mutant Cyclin T1 proteins inhibit HIV transcription by specifically degrading Tat (2008) (18)
- N-acetyl-L-cysteine enhances chemotherapeutic effect on prostate cancer cells (2002) (18)
- Proteolytic processing of nuclear factor kappa B by calpain in vitro. (1996) (18)
- Dominant negative mutant cyclin T1 proteins that inhibit HIV transcription by forming a kinase inactive complex with Tat. (2008) (17)
- Identification and purification of the enhancer-binding factor of human immunodeficiency virus-1. Multiple proteins and binding to other enhancers. (1989) (17)
- MOLECULAR ANALYSIS OF CONSTITUTIVE IL-1α GENE EXPRESSION IN HUMAN MELANOMA CELLS: AUTHOCRINE STIMULATION THROUGH NF-κB ACTIVATION BY ENDOGENOUS IL-1α☆ (1998) (17)
- Involvement of Vascular Endothelial Growth Factor in Kaposi's Sarcoma Associated with Acquired Immunodeficiency Syndrome (1996) (17)
- Bidirectional regulation of c-fos promoter by an oncogenic gip2 mutant of G alpha i2. A novel implication of retinoblastoma gene product. (1994) (16)
- HIV-1 replication is inhibited by a pseudo-substrate peptide that blocks Tat transactivation. (2000) (15)
- Sensitive and Specific Enzyme-Linked Immunosorbent Assay Using Chemiluminescence for Detection of Severe Acute Respiratory Syndrome Viral Infection (2007) (15)
- The protein tyrosine kinase Fyn activates transcription from the HIV promoter via activation of NFkB-like DNA-binding proteins (1995) (15)
- Inhibition of Inflammatory Cytokine Production from Rheumatoid Synovial Fibroblasts by a Novel IκB Kinase Inhibitor (2010) (14)
- Cyclin T1 stabilizes expression levels of HIV‐1 Tat in cells (2009) (13)
- Identification of transcriptional suppressor proteins that bind to the negative regulatory element of the human immunodeficiency virus type 1. (1991) (13)
- Knock down of hSNF5/Ini1 causes cell cycle arrest and apoptosis in a p53-dependent manner. (2007) (13)
- Huntingtin-interacting protein-1-related protein of rat (rHIP1R) is localized in the postsynaptic regions (2003) (13)
- Involvement of Sp1 in Butyric Acid-Induced HIV-1 Gene Expression (2015) (13)
- Cancer-derived UTX TPR mutations G137V and D336G impair interaction with MLL3/4 complexes and affect UTX subcellular localization (2020) (13)
- Presence of NF-kappaB-like and IkappaB-like immunoreactivities in postsynaptic densities. (1997) (13)
- 2-Glycineamide-5-chlorophenyl 2-pyrryl ketone, a non-benzodiazepin Tat antagonist, is effective against acute and chronic HIV-1 infections in vitro. (1996) (13)
- Superinduction of trans-activation accounts for augmented human immunodeficiency virus replication in HTLV-I-transformed cells. (1987) (12)
- Inhibitory effects of IFN-gamma on HIV-1 replication in latently infected cells. (2002) (12)
- NF-κB Signature on the Aging Wall (2010) (12)
- Molecular Dynamics Simulation and Experimental Verification of the Interaction between Cyclin T1 and HIV-1 Tat Proteins (2015) (11)
- Gold compounds inhibit adhesion of human cancer cells to vascular endothelial cells. (2003) (11)
- Interaction between von Hippel-Lindau Protein and Fatty Acid Synthase Modulates Hypoxia Target Gene Expression (2017) (11)
- Recombinant Vpr (rVpr) causes augmentation of HIV-1 p24 Ag level in U1 cells through its ability to induce the secretion of TNF. (2002) (11)
- Alteration of the cellular response to interleukin-1ß by SV40 large T antigen in rheumatoid synovial fibroblasts (1999) (11)
- TUMOUR NECROSIS FACTOR AND HIV: A NOTE OF CAUTION (1988) (11)
- The epigenetic alteration of synovial cell gene expression in rheumatoid arthritis and the roles of nuclear factor κB and Notch signaling pathways (2005) (11)
- Conservation of the central proline‐rich (PxxP) motifs of human immunodeficiency virus type 1 Nef protein during the disease progression in two hemophiliac patients (1999) (10)
- Anti-Tat MTT assay: a novel anti-HIV drug screening system using the viral regulatory network of replication. (1995) (10)
- Tautomycetin suppresses the TNFα/NF-κB pathway via inhibition of IKK activation (1992) (10)
- Enhanced invasion of Tax-expressing fibroblasts into the basement membrane is repressed by phosphorylated ascorbate with simultaneous decreases in intracellular oxidative stress and NF-kappa B activation. (2000) (10)
- Differential regulation of the regulatory subunits for phosphatidylinositol 3-kinase in response to motor nerve injury. (2004) (10)
- Constrained optimization using a multipoint type chaotic Lagrangian method with a coupling structure (2013) (9)
- Production of 4-hydroxybutyrate from succinate semialdehyde in butyrate biosynthesis in Porphyromonas gingivalis. (2015) (9)
- Analysis and Improvements of the Pareto Optimal Solution Visualization Method Using the Self-Organizing Maps (2015) (9)
- Functional characterization of human cyclin T1 N-terminal region for human immunodeficiency virus-1 Tat transcriptional activation. (2011) (9)
- Structural and functional analysis of the control region of the human DNA topoisomerase II alpha gene in drug-resistant cells. (1999) (9)
- [Some phenolic compounds stimulate the proliferation of human pulpal fibroblasts]. (1989) (9)
- Activation of a novel KpnI transcript by downstream integration of a human T-lymphotropic virus type I provirus. (1986) (9)
- Impaired plant growth and development caused by human immunodeficiency virus type 1 Tat (2010) (8)
- Genetic heterogeneity of the immunogenic viral capsid protein region of human parvovirus B19 isolates obtained from an outbreak in a pediatric ward (1999) (8)
- Thioredoxin and mechanism of inflammatory response. (2002) (8)
- Optimal Design of Buffer Material in the Geological Disposal of Radioactive Wastes Using the Satisficing Trade‐off Method and a Self‐Organizing Map (2014) (8)
- NF-kappa B signature on the aging wall. (2010) (8)
- Interaction of 68-kDa TAR RNA-binding protein and other cellular proteins with prion protein-RNA stem-loop. (1995) (8)
- Formation of a small ribonucleoprotein particle between Tat protein and trans-acting response element in human immunodeficiency virus-infected cells. (1991) (8)
- Dihydrotestosterone inhibits tumor necrosis factor alpha induced interleukin-1alpha mRNA expression in rheumatoid fibroblast-like synovial cells. (2007) (8)
- Cytokinin dehydrogenase differentially regulates cytokinin and indirectly affects hydrogen peroxide accumulation in tomato leaf. (2012) (8)
- Low molecular weight lignin suppresses activation of NF-kappaB and HIV-1 promoter. (2008) (8)
- Follicular Dendritic Cells Activate HIV-1 Replication in Monocytes/Macrophages through a Juxtacrine Mechanism Mediated by P-Selectin Glycoprotein Ligand 11 (2009) (8)
- Constrained optimization using the quasi-chaotic optimization method with the exact penalty function and the sequential quadratic programming (2011) (8)
- The Improved Draining Method and Its Application to Proper Benchmark Problems (2006) (7)
- Molecular analysis of constitutive IL-1alpha gene expression in human melanoma cells: autocrine stimulation through NF-kappaB activation by endogenous IL-1alpha. (1998) (7)
- Molecular characterization of human T-lymphotropic leukemia virus type III associated with the acquired immunodeficiency syndrome. (1984) (7)
- Angiotensinogen synthesis in the liver is independent of physiological estrogen levels. (1995) (6)
- Constrained optimization using the lagrangian method and the improved discrete gradient chaos model (2009) (6)
- Identification of a New Serine Kinase That Activates NFKB by Direct Phosphorylation* (2001) (6)
- Molecular docking analysis of the protein–protein interaction between RelA‐associated inhibitor and tumor suppressor protein p53 and its inhibitory effect on p53 action (2008) (6)
- A unique mechanism of desensitization to lipolysis mediated by β3-adrenoceptor in rats with thermal injury. (1999) (6)
- Clonal selection of HIV type 1 variants associated with resistance to foscarnet in vitro: confirmation by molecular evolutionary analysis. (1997) (6)
- Tautomycetin suppresses the TNFalpha/NF-kappaB pathway via inhibition of IKK activation. (2008) (6)
- MD simulation of the Tat/Cyclin T1/CDK9 complex revealing the hidden catalytic cavity within the CDK9 molecule upon Tat binding (2017) (6)
- Quantification of the HIV transcriptional activator complex in live cells by image‐based protein–protein interaction analysis (2016) (6)
- Multi-Objective Optimization Using Coupled Discrete Gradient Model (2010) (6)
- Interaction of viral and cellular factors with the HTLV-III LTR target sequences in vitro. (1987) (6)
- Global optimization using a multi-point type quasi-chaotic optimization method with the simultaneous perturbation gradient approximation (2010) (6)
- Involvement of RelA-associated inhibitor in regulation of trophoblast differentiation via interaction with transcriptional factor specificity protein-1. (2007) (6)
- Cooperation between the chloroplast psbA 5'-untranslated region and coding region is important for translational initiation: the chloroplast translation machinery cannot read a human viral gene coding region. (2016) (5)
- The Tat/P-TEFb Protein-Protein Interaction Determining Transcriptional Activation of HIV. (2017) (5)
- Optimal assignment of the battery for the power system considering the voltage stability under the penetration of the renewable energy sources (2015) (5)
- The protein tyrosine kinase Fyn activates transcription from the HIV promoter via activation of NF kappa B-like DNA-binding proteins. (1995) (5)
- Microbial interaction between HIV-1 and anaerobic bacteria producing butyric acid: its potential implication in AIDS progression (2012) (5)
- Repressive Effect of the nef cDNA of Human Immunodeficiency Virus Type 1 on the Promoter Activity of the Viral Long Terminal Repeat (1990) (5)
- Interaction between Endogenous Bacterial Flora and Latent HIV Infection (2013) (4)
- Unsung Hero Robert C. Gallo (2009) (4)
- A novel IKKα inhibitor, noraristeromycin, blocks the chronic inflammation associated with collagen-induced arthritis in mice (2014) (4)
- Equilibrium Solution Search on a Selfish Routing Problem with Multiple Constraints Using the Variable Metric Gradient Projection Method (2015) (4)
- LTR-directed homologous recombination of full-length HIV-1 provirus clone inrecA(−) bacteria (2005) (4)
- A learning algorithm with a gradient normalization and a learning rate adaptation for the mini-batch type learning (2017) (4)
- Determination of a splice acceptor site of pX gene in HTLV-I infected cells. (1985) (4)
- Visualization of Pareto Optimal Solution Sets Using the Growing Hierarchical Self-Organizing Maps (2017) (4)
- Induction of 8-oxoguanine DNA Glycosylase 1 Gene Expression by HIV-1 Tat (2005) (4)
- An intrinsic guanine nucleotide exchange inhibitor in Gi2 alpha. Significance of G-protein self-suppression which antagonizes receptor signal. (1994) (3)
- An Efficiency Improvement of the Equilibrium Solution Search on the Selfish Routing Game by Removing Redundant Paths (2016) (3)
- Role of thioredoxin in the redox regulation of gene expression in inflammatory diseases (2000) (3)
- A Pareto optimal solution visualization method using SOM-NG with learning parameter optimization (2016) (3)
- Molecular Cloning of cDNA for Human Placental Poly(ADP-Ribose) Polymerase and Decreased Expression of its Gene during Retinoic Acid-Induced Granulocytic Differentiation of HL-60 Cells (1989) (3)
- Establishment of a simple and quantitative immunospot assay for detecting anti-type II collagen antibody using an infrared fluorescence imaging system (IFIS). (2005) (3)
- Profit Sharing Using a Dynamic Reinforcement Function Considering Expectation Value of Reinforcement (2009) (3)
- A unique mechanism of desensitization to lipolysis mediated by beta(3)-adrenoceptor in rats with thermal injury. (1999) (3)
- [Multi-stop carcinogenesis model for adult T-cell leukemia]. (1990) (3)
- Replication-defective HIV isolated from seronegative individuals at high risk for HIV infection. (2005) (3)
- Fast Back Propagation Learning Using Optimization of Learning Rate for Pulsed Neural Networks (2008) (3)
- A Method for Design of a Growing Complex Network (2014) (2)
- [In vitro cultivation of human pulpal fibroblast strains--permanent and deciduous teeth]. (1989) (2)
- [NF-kappaB as a therapeutic target of rheumatoid arthritis]. (2007) (2)
- Global optimization with the PSO coupling‐type discrete gradient chaos model (2008) (2)
- A growing complex network design method with an adaptive multi-objective genetic algorithm and an inner link restructuring method (2012) (2)
- Oxidative Stress in Rheumatoid Arthritis (2005) (2)
- Visualization of Pareto optimal solutions using MIGSOM (2015) (2)
- Elimination of HIV-infected cells by lymphocytes armed with a bifunctional antibody to gp120 of HIV and CD3. (1993) (2)
- Overlapping glycosylation sequon influences the glycosylation pattern of a chimeric protein expressed in tomato leaf and callus. (2013) (2)
- Constrained optimization using the chaotic Lagrange quasi-Newton method - A basic study of its search trajectory and its search capability (2013) (2)
- An immunofluorescent study on anti-synovial tissue antibody in the body fluid from patients with rheumatoid arthritis. (1965) (2)
- A Collaborative Learning Automata Team Model for Modeling Multi-Agent Systems (2018) (2)
- A Growing Complex Network Design Method (2011) (2)
- Constrained optimization using the chaotic Lagrangian method and the simultaneous perturbation gradient approximation (2009) (2)
- Improvement of particle swarm optimization based on the repetitive search guideline (2008) (2)
- Fast backpropagation learning using optimization of learning rate for pulsed neural networks (2011) (2)
- Calcium as an intracellular signal for cell proliferation response. Studies on IGF-II induced DNA synthesis in Balb/c 3T3 mouse fibroblasts. (1991) (2)
- Corrigendum to: Conservation of the central proline‐rich (PxxP) motifs of human immunodeficiency virus type 1 Nef protein during the disease progression in two hemophiliac patients (FEBS 22727) (2000) (1)
- Molecular Mechanisms of HIV-1 Latency and Its Breakdown by Periodontal Diseases (2010) (1)
- Follicular Dendritic Cells Activate HIV-1 Replication in Monocytes/Macrophages through a Juxtacrine Mechanism Mediated by P-Selectin Glycoprotein Ligand 1 (2009) (1)
- 9 – Redox Regulation of NF-κB (2000) (1)
- An Intrinsic Guanine Nucleotide Exchange Inhibitor in Gi2a (1994) (1)
- Reactivation of latent HIV-1 by a wide variety of butyric acid-producing bacteria (2012) (1)
- P-Selectin Glycoprotein Ligand 1 through a Juxtacrine Mechanism Mediated Replication in Monocytes / Macrophages Follicular Dendritic Cells Activate HIV-1 (2009) (1)
- A KDM6 inhibitor potently induces ATF4 and its target gene expression through HRI activation and by UTX inhibition (2021) (1)
- Track A Basic Science (2012) (1)
- The interaction with Sp 1 and reduction in the activity of histone deacetylase 1 are critical for the constitutive gene expression of IL-1 in human melanoma cells (2007) (1)
- Oxygen Radicals, Redox Regulation of the NF-kB Signaling and Disease Control by Antioxidants(Review) (1996) (1)
- Regulation of HIV replication by a host transcription factor NFκB (1994) (1)
- A buffer material optimal design in the radioactive wastes geological disposal using the satisficing trade-off method and the self-organizing map (2012) (1)
- A Learning Method for Block-Based Neural Networks with Structure Search Based on the Least Number of Routes (2017) (1)
- The Search for Nash Equilibrium Solutions with Replicator Equations Derived from Gradient Dynamics on a Simplex (2007) (1)
- Constrained Global Optimization Methods by Using Inner State Models with Nonlinear Dissipative Dynamics (2003) (1)
- Mixed integer optimization using the quasi-chaotic optimization with the discrete simultaneous perturbation stochastic approximation (2011) (1)
- The robustness of a Nash equilibrium simulation model: Game-theoretic approach using variable metric projection method (2009) (1)
- An optimal routing search method on the network routing problem using the sequential minimal optimization (2017) (1)
- The global optimization with the PSO coupling type discrete gradient chaos model (2006) (1)
- A Chaotic Optimization Method without Initial Sampling Parameter Tuning (2012) (1)
- Block-Based Neural Networks with Pulsed Neuron Model (Japanese Title: ?????????????????????????????? (2010) (1)
- In vitro antiviral activity of Mentha cordifolia plant extract in HIV-1 latently infected cells using an established human cell line. (2021) (1)
- Heuristic Optimization and Modeling (1): Optimization Problem (2011) (0)
- Heuristic optimization and modeling (2); Classical optimization method and particle swarm optimization (2012) (0)
- REDOX REGULATION OF THE NF-κB SIGNALING PATHWAY AND DISEASE CONTROL (1996) (0)
- Optimal assignment of the battery for the electric power system against N-1 accident (2016) (0)
- Global Optimization Constrained on the Hypersphere by Using Continuous Dissipative Chaos (2003) (0)
- Negative transactivation ofcAMPresponseelement byfamilial Alzheimer's mutantsofAPP (1996) (0)
- A Learning Method for Block-Based Neural Networks Using Particle Swarm Optimization (2009) (0)
- gingivalis Involves Histone Modification Periodontopathic Bacterium Porphyromonas Reactivation of Latent HIV-1 Infection by the (2013) (0)
- Redox regulation of NF-kB and its therapeutic implications in AIDS and RA (1998) (0)
- A design method for the complex network growth model (2013) (0)
- [Biological response to oxidative stress and the signal transduction pathway of NF-kappa B]. (1999) (0)
- Voacanga globosa Spirobisindole Alkaloids Exert Antiviral Activity in HIV Latently Infected Cell Lines by Targeting the NF-kB Cascade: In Vitro and In Silico Investigations (2022) (0)
- HIV-1 Tat Blocks the Expression of MHC CIass II Genes in HIV Infection (2003) (0)
- Expression and functional analysis of Cancer susceptibility candidate 1 ( Casc1 ) gene in the rodent maturing testis (2017) (0)
- Global Optimization Using a Multi-point Type Discrete Inertial Time-varying Model (2010) (0)
- Identification of a novel CDK9 inhibitor targeting the intramolecular hidden cavity of CDK9 induced by Tat binding (2022) (0)
- An efficient improvement of the optimal routing search on the network routing problem by removing redundant paths (2016) (0)
- [Oxy-stress response and its control mechanism: overview]. (1999) (0)
- Pro-apoptotic actions of 53BP2 in a human pancreatic cancer cell line (2000) (0)
- Identification of Super-Enhancer-Associated Cancer Genes Provides Novel Therapeutic Targets in Adult T-Cell Leukemia/Lymphoma (2016) (0)
- Heuristic optimization and modeling (3): Genetic algorithm and differential evolution (2012) (0)
- Dual Use in Pathogen Research (2013) (0)
- Human pulpal fibroblast strains formed hydroxyapatite in vitro (1990) (0)
- High prevalence of the antibody against Syncytin-1 in schizophrenia (2018) (0)
- Inhibition of Cytokines and ICAM-1 Induction in Rheumatoid Fibroblasts by anti-NF-κB Reagents (1998) (0)
- Effect of Cepharantin on leukocyte chemotaxis induced by venom peptides. (1989) (0)
- P-A2 Development of anti-Tat compound: MD Simulation of the Tat/Cyclin T1/CDK9 Complex Revealing the Hidden Catalytic Cavity within the CDK9 Molecule Upon Tat Binding (2018) (0)
- A Chaotic Optimization Method Using a Bifurcation Tuning by an Objective Function Transformation : A Proposal of Global Optimization Method “Draining Method” (2006) (0)
- A Pareto Optimal Solution Visualization Method Using an Improved Growing Hierarchical Self-Organizing Maps Based on the Batch Learning (2016) (0)
- Involves Histone Modification gingivalis Porphyromonas Periodontopathic Bacterium Reactivation of Latent HIV-1 Infection by the (2009) (0)
- Sensitive and Specific Enzyme-Linked Immunosorbent Assay Using Chemiluminescence for Detection of Severe Acute Respiratory Syndrome Viral Infection (cid:1) (2007) (0)
- An Application of Reccurent Pulsed Neural Networks to Time-Series Processing of Autonomous Mobile Robot (2016) (0)
- Optimal assignment of the battery for the power system by the response surface method with the radial basis function networks (2015) (0)
- Table of Contents (1996) (0)
- NF-κB activation inhibitor (2004) (0)
- GTP‐binding protein‐activator sequences in the insulin receptor (1994) (0)
- Author Correction: Interaction between von Hippel-Lindau Protein and Fatty Acid Synthase Modulates Hypoxia Target Gene Expression (2018) (0)
- [Regulatory system of HIV transcription as a feasible therapeutic target]. (2007) (0)
- Application of in-gel kinase assay to study transcription factors (1998) (0)
- Congestion control of HighSpeed TCP using the partial collaborative learning automaton team mode (2015) (0)
- Gamification of the Optimization Problem and Multi-point Type Optimization Methods (2013) (0)
- Heuristic Optimization and Modeling(1): Optimization Problem (2011) (0)
- Congestion Control of HighSpeed TCP Using Learning Automaton (2017) (0)
- TheImproved Draining Methodand ItsApplication toProper Benchmark Problems (2006) (0)
- HIV-1 Tat enhances the stabilization of the HIV transcriptional activator complex by modifying its local structure. (2017) (0)
- Global Optimization Using a Multi-point Type Quasi-chaotic Optimization Method without Initial Sampling Parameter Tuning (2010) (0)
- [Current discussion on dual use issues in microbiological research]. (2013) (0)
- A Solution Method Combining Simulated Annealing and Graph-based Heuristics for Operational Planning and Scheduling Benchmark Problems in an Automatic Picking System (2019) (0)
- Kansei learning using the artificial intelligence and its applications (2019) (0)
- Induction of apoptosis in a pancreatic cancer cell line by IκB gene transfer (1998) (0)
- Involvement of multiple pro-apoptotic cascades in the CCK-induced pancreatitis (1998) (0)
- P19-16. Potential of an HIV-1 Tat fusion protein expressed in tomato as a plant-based HIV vaccine (2009) (0)
- Optimization of Water Supply Pump Operation Scheduling Using Branch and Bound Method (2018) (0)
- Analysis of transcription factors by gel shift and in-gel kinase assays (1998) (0)
- Chaotic Optimization Method without Initial Sampling Parameter Tuning - Empirical Comparisons of Two Approaches in Various Problems (2013) (0)
- Conversion ofG-protein specificity ofinsulin-like growth factor II/mannose 6-phosphate receptor byexchanging ofashort region with/8-adrenergic receptor (1993) (0)
- Redox Regulation of the Nuclear Factor Kappa B (NF-κB) Signaling Pathway and Disease Control (1998) (0)
- [Positive and negative regulation of transcription from HIV provirus]. (2011) (0)
- Abstract 5487: Identification of super-enhancer-associated cancer genes provides novel therapeutic targets in adult T-cell leukemia/lymphoma (2017) (0)
- Interaction between von Hippel-Lindau Protein and Fatty Acid Synthase Modulates Hypoxia Target Gene Expression (2017) (0)
- The Global Optimization by the Multi-agent Type Hamiltonian Algorithm with the Concept in the Meta-heuristics (2006) (0)
- Constrained optimization using the chaotic sequential quadratic approximation type Lagrange quasi-Newton method (2014) (0)
- Heuristic optimization and modeling (4): Modeling with heuristic methods (2012) (0)
- Tissue specific expression of multiple gamma glutamyl transpeptidase ggt messenger rnas with heterogeneous 5 ends in the rat (1991) (0)
- Global optimization using the draining method and the simultaneous perturbation gradient approximation (2010) (0)
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What Schools Are Affiliated With Takashi Okamoto?
Takashi Okamoto is affiliated with the following schools: