Takashi Tsuruo

Q: What Schools Are Affiliated With Takashi Tsuruo

Takashi Tsuruo is affiliated with the following schools: Meijo University, Yale University, Niigata University, University of Tokyo, Toho University

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Takashi Tsuruo

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Takashi Tsuruo

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Takashi Tsuruo's Degrees

PhD Pharmacology Kyoto University
Doctorate Medicine Kyoto University

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Takashi Tsuruo's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues. (1987) (2758)
Overcoming of vincristine resistance in P388 leukemia in vivo and in vitro through enhanced cytotoxicity of vincristine and vinblastine by verapamil. (1981) (1506)
Modulation of Akt kinase activity by binding to Hsp90. (2000) (955)
Increased accumulation of vincristine and adriamycin in drug-resistant P388 tumor cells following incubation with calcium antagonists and calmodulin inhibitors. (1982) (708)
Constitutive activation of the 41-/43-kDa mitogen-activated protein kinase signaling pathway in human tumors (1999) (708)
A synthetic inhibitor of histone deacetylase, MS-27-275, with marked in vivo antitumor activity against human tumors. (1999) (703)
Immunohistochemical localization in normal tissues of different epitopes in the multidrug transport protein P170: evidence for localization in brain capillaries and crossreactivity of one antibody with a muscle protein. (1989) (611)
Augmentation of adriamycin, melphalan, and cisplatin cytotoxicity in drug-resistant and -sensitive human ovarian carcinoma cell lines by buthionine sulfoximine mediated glutathione depletion. (1985) (585)
Functional role for the 170- to 180-kDa glycoprotein specific to drug-resistant tumor cells as revealed by monoclonal antibodies. (1986) (561)
Clinical significance of multidrug resistance P-glycoprotein expression on acute nonlymphoblastic leukemia cells at diagnosis. (1992) (520)
Molecular targeting therapy of cancer: drug resistance, apoptosis and survival signal (2003) (487)
Tissue distribution of P-glycoprotein encoded by a multidrug-resistant gene as revealed by a monoclonal antibody, MRK 16. (1988) (478)
C421A polymorphism in the human breast cancer resistance protein gene is associated with low expression of Q141K protein and low-level drug resistance. (2002) (446)
De novo fatty-acid synthesis and related pathways as molecular targets for cancer therapy (2009) (443)
Circumvention of vincristine and Adriamycin resistance in vitro and in vivo by calcium influx blockers. (1983) (407)
Rap1 translates chemokine signals to integrin activation, cell polarization, and motility across vascular endothelium under flow (2003) (389)
Reversal mechanism of multidrug resistance by verapamil: direct binding of verapamil to P-glycoprotein on specific sites and transport of verapamil outward across the plasma membrane of K562/ADM cells. (1989) (383)
Functional expression of P-glycoprotein in apical membranes of human intestinal Caco-2 cells. Kinetics of vinblastine secretion and interaction with modulators. (1993) (376)
Akt-dependent Phosphorylation of p27Kip1Promotes Binding to 14-3-3 and Cytoplasmic Localization* (2002) (375)
Role of aminopeptidase N (CD13) in tumor‐cell invasion and extracellular matrix degradation (1993) (344)
Domain Mapping Studies Reveal That the M Domain of hsp90 Serves as a Molecular Scaffold to Regulate Akt-Dependent Phosphorylation of Endothelial Nitric Oxide Synthase and NO Release (2002) (343)
[Functional involvement of P-glycoprotein in blood-brain barrier]. (1992) (335)
Involvement of 14‐3‐3 proteins in nuclear localization of telomerase (2000) (333)
Brain pericytes contribute to the induction and up-regulation of blood–brain barrier functions through transforming growth factor-β production (2005) (314)
Dominant‐negative inhibition of breast cancer resistance protein as drug efflux pump through the inhibition of S‐S dependent homodimerization (2002) (305)
Purification of the 170- to 180-kilodalton membrane glycoprotein associated with multidrug resistance. 170- to 180-kilodalton membrane glycoprotein is an ATPase. (1988) (304)
P-glycoprotein as the drug efflux pump in primary cultured bovine brain capillary endothelial cells. (1992) (288)
Molecular Identification of Aggrus/T1α as a Platelet Aggregation-inducing Factor Expressed in Colorectal Tumors* (2003) (277)
Pim kinases promote cell cycle progression by phosphorylating and down-regulating p27Kip1 at the transcriptional and posttranscriptional levels. (2008) (272)
Potentiation of vincristine and Adriamycin effects in human hemopoietic tumor cell lines by calcium antagonists and calmodulin inhibitors. (1983) (261)
Potent antitumor activity of MS-247, a novel DNA minor groove binder, evaluated by an in vitro and in vivo human cancer cell line panel. (1999) (261)
Actin cleavage by CPP-32/apopain during the development of apoptosis (1997) (261)
Characteristics of resistance to adriamycin in human myelogenous leukemia K562 resistant to adriamycin and in isolated clones. (1986) (258)
Brain capillary endothelial cells express two forms of erythropoietin receptor mRNA. (1996) (255)
Caspase-mediated cleavage of p21Waf1/Cip1 converts cancer cells from growth arrest to undergoing apoptosis (1999) (251)
Apollon ubiquitinates SMAC and caspase-9, and has an essential cytoprotection function (2004) (251)
Decreased expression of DNA topoisomerase I in camptothecin-resistant tumor cell lines as determined by a monoclonal antibody. (1990) (250)
Dephosphorylated hypoxia-inducible factor 1α as a mediator of p53-dependent apoptosis during hypoxia (2001) (248)
The 4F2hc/LAT1 complex transports l-DOPA across the blood–brain barrier (2000) (245)
Predominant suppression of apoptosome by inhibitor of apoptosis protein in non-small cell lung cancer H460 cells: therapeutic effect of a novel polyarginine-conjugated Smac peptide. (2003) (242)
Breast cancer resistance protein exports sulfated estrogens but not free estrogens. (2003) (241)
MECHANISMS OF MULTIDRUG RESISTANCE AND IMPLICATIONS FOR THERAPY (1988) (237)
Effects of quinidine and related compounds on cytotoxicity and cellular accumulation of vincristine and adriamycin in drug-resistant tumor cells. (1984) (236)
Cyclooxygenase-2 overexpression correlates with tumour recurrence, especially haematogenous metastasis, of colorectal cancer (2000) (235)
Telomerase inhibition, telomere shortening, and senescence of cancer cells by tea catechins. (1998) (233)
A human IAP-family gene, apollon, expressed in human brain cancer cells. (1999) (232)
Identification of actin as a substrate of ICE and an ICE-like protease and involvement of an ICE-like protease but not ICE in VP-16-induced U937 apoptosis. (1995) (226)
Interference with PDK1-Akt survival signaling pathway by UCN-01 (7-hydroxystaurosporine) (2002) (224)
Enhanced Expression of Aggrus (T1alpha/Podoplanin), a Platelet-Aggregation-Inducing Factor in Lung Squamous Cell Carcinoma (2005) (223)
Effect on tumor cells of blocking survival response to glucose deprivation. (2004) (221)
Blocking telomerase by dietary polyphenols is a major mechanism for limiting the growth of human cancer cells in vitro and in vivo. (2003) (221)
Distribution of multidrug resistance-associated P-glycoprotein in normal and neoplastic human tissue (1990) (219)
G-Quadruplex stabilization by telomestatin induces TRF2 protein dissociation from telomeres and anaphase bridge formation accompanied by loss of the 3′ telomeric overhang in cancer cells (2006) (218)
Phosphorylation of p27Kip1 at Threonine 198 by p90 Ribosomal Protein S6 Kinases Promotes Its Binding to 14-3-3 and Cytoplasmic Localization* (2003) (216)
Phosphorylation of the Mr 170,000 to 180,000 glycoprotein specific to multidrug-resistant tumor cells: effects of verapamil, trifluoperazine, and phorbol esters. (1987) (215)
Alteration in Copy Numbers of Genes as a Mechanism for Acquired Drug Resistance (2004) (212)
c-Jun NH2-terminal Kinase-mediated Activation of Interleukin-1β Converting Enzyme/CED-3-like Protease during Anticancer Drug-induced Apoptosis* (1997) (207)
Blockade of the stromal cell-derived factor-1/CXCR4 axis attenuates in vivo tumor growth by inhibiting angiogenesis in a vascular endothelial growth factor-independent manner. (2005) (194)
The platelet aggregation-inducing factor aggrus/podoplanin promotes pulmonary metastasis. (2007) (193)
Involvement of Hsp90 in Signaling and Stability of 3-Phosphoinositide-dependent Kinase-1* (2002) (191)
Insulin and Insulin‐like Growth Factor 1 Stimulate Proliferation of Metastatic Variants of Colon Carcinoma 26 (1989) (191)
Caspase-mediated cleavage of cytoskeletal actin plays a positive role in the process of morphological apoptosis (1999) (189)
ASK1 mediates apoptotic cell death induced by genotoxic stress (1999) (186)
Characterization of the ATPase activity of the Mr 170,000 to 180,000 membrane glycoprotein (P-glycoprotein) associated with multidrug resistance in K562/ADM cells. (1988) (181)
Prediction of sensitivity of advanced non-small cell lung cancers to gefitinib (Iressa, ZD1839). (2004) (177)
P-glycoprotein function involves conformational transitions detectable by differential immunoreactivity. (1997) (176)
Acceleration of apoptotic cell death after the cleavage of Bcl-XL protein by caspase-3-like proteases (1998) (172)
ATP‐binding properties of P glycoprotein from multidrug‐resistant KB cells (1987) (170)
Ceramide and Reactive Oxygen Species Generated by H2O2 Induce Caspase-3-independent Degradation of Akt/Protein Kinase B* (2002) (165)
Apoxin I, a Novel Apoptosis-inducing Factor with L-Amino Acid Oxidase Activity Purified from Western Diamondback Rattlesnake Venom* (1997) (164)
5-Fluorouracil induces apoptosis in human colon cancer cell lines with modulation of Bcl-2 family proteins. (1998) (163)
Binding and phosphorylation of par-4 by akt is essential for cancer cell survival. (2005) (159)
Cyclic hydroxamic-acid-containing peptide 31, a potent synthetic histone deacetylase inhibitor with antitumor activity. (2001) (159)
Chemical genomics identifies the unfolded protein response as a target for selective cancer cell killing during glucose deprivation. (2009) (157)
Differences in drug sensitivity among tumor cells from parental tumors, selected variants, and spontaneous metastases. (1981) (156)
Tankyrase 1 as a target for telomere-directed molecular cancer therapeutics. (2005) (154)
Aggrus: a diagnostic marker that distinguishes seminoma from embryonal carcinoma in testicular germ cell tumors (2004) (153)
Immunocytochemical localization of P170 at the plasma membrane of multidrug-resistant human cells. (1987) (152)
Glyoxalase I is involved in resistance of human leukemia cells to antitumor agent-induced apoptosis. (2000) (152)
Drug resistance mediated by cellular stress response to the microenvironment of solid tumors. (1999) (149)
Effect of bioflavonoids on vincristine transport across blood-brain barrier. (2000) (148)
FJ5002: a potent telomerase inhibitor identified by exploiting the disease-oriented screening program with COMPARE analysis. (1999) (148)
Aspartate-based inhibitor of interleukin-1 beta-converting enzyme prevents antitumor agent-induced apoptosis in human myeloid leukemia U937 cells. (1995) (147)
A monoclonal antibody-Pseudomonas toxin conjugate that specifically kills multidrug-resistant cells. (1987) (145)
Akt/Protein Kinase B-Dependent Phosphorylation and Inactivation of WEE1Hu Promote Cell Cycle Progression at G2/M Transition (2005) (144)
A DNA-topoisomerase-II-binding protein with eight repeating regions similar to DNA-repair enzymes and to a cell-cycle regulator. (1997) (142)
Characterization of metastatic clones derived from a metastatic variant of mouse colon adenocarcinoma 26. (1983) (141)
Enhancement of vincristine- and adriamycin-induced cytotoxicity by verapamil in P388 leukemia and its sublines resistant to vincristine and adriamycin. (1982) (139)
Competitive inhibition by verapamil of ATP-dependent high affinity vincristine binding to the plasma membrane of multidrug-resistant K562 cells without calcium ion involvement. (1989) (138)
Selective induction of apoptosis in Philadelphia chromosome-positive chronic myelogenous leukemia cells by an inhibitor of BCR–ABL tyrosine kinase, CGP 57148 (1998) (138)
Phosphatidylserine externalization is a downstream event of interleukin-1 beta-converting enzyme family protease activation during apoptosis. (1997) (137)
Elevated expression of DNA topoisomerase II in camptothecin-resistant human tumor cell lines. (1990) (136)
Podoplanin expression in primary central nervous system germ cell tumors: a useful histological marker for the diagnosis of germinoma (2006) (134)
Expression of the mdr-1/P-170 gene in patients with acute lymphoblastic leukemia. (1989) (132)
Transfection with protein kinase C alpha confers increased multidrug resistance to MCF-7 cells expressing P-glycoprotein. (1991) (131)
Telomere shortening and growth inhibition of human cancer cells by novel synthetic telomerase inhibitors MST-312, MST-295, and MST-1991. (2002) (130)
ATP/Mg2+-dependent binding of vincristine to the plasma membrane of multidrug-resistant K562 cells. (1988) (130)
Modulation of Heat-shock Protein 27 (Hsp27) Anti-apoptotic Activity by Methylglyoxal Modification* (2002) (129)
Promotion by verapamil of vincristine responsiveness in tumor cell lines inherently resistant to the drug. (1983) (129)
Proteasome inhibition circumvents solid tumor resistance to topoisomerase II-directed drugs. (2000) (128)
MMP-1 is a prognostic marker for hematogenous metastasis of colorectal cancer. (2000) (128)
Fak/Src signaling in human intestinal epithelial cell survival and anoikis: Differentiation state‐specific uncoupling with the PI3‐K/Akt‐1 and MEK/Erk pathways (2007) (126)
Identification of ATF-3, caveolin-1, DLC-1, and NM23-H2 as putative antitumorigenic, progesterone-regulated genes for ovarian cancer cells by gene profiling (2005) (126)
Antitumor activity of a novel podophyllotoxin derivative (TOP-53) against lung cancer and lung metastatic cancer. (1996) (124)
Inhibition of haematogenous metastasis of colon cancer in mice by a selective COX-2 inhibitor, JTE-522 (1999) (122)
Human melanoma invasion and metastasis enhancement by high expression of aminopeptidase N/CD13 (1995) (122)
Reversal of acquired resistance to vinca alkaloids and anthracycline antibiotics. (1983) (121)
Selective activation of apoptosis program by S-p-bromobenzylglutathione cyclopentyl diester in glyoxalase I-overexpressing human lung cancer cells. (2001) (119)
Fractional retention of technetium-99m-sestamibi as an index of P-glycoprotein expression in untreated breast cancer patients. (1997) (118)
Rhizoxin, a macrocyclic lactone antibiotic, as a new antitumor agent against human and murine tumor cells and their vincristine-resistant sublines. (1986) (118)
Comparative study on reversal efficacy of SDZ PSC 833, cyclosporin A and verapamil on multidrug resistance in vitro and in vivo. (1995) (116)
Topology of P-glycoprotein as determined by epitope mapping of MRK-16 monoclonal antibody. (1993) (116)
Small Molecules Destabilize cIAP1 by Activating Auto-ubiquitylation* (2008) (115)
Involvement of 3-Phosphoinositide-dependent Protein Kinase-1 in the MEK/MAPK Signal Transduction Pathway* (2004) (115)
Serum and plasma M(r) 92,000 progelatinase levels correlate with spontaneous metastasis of rat 13762NF mammary adenocarcinoma. (1993) (114)
Involvement of the lysophosphatidic acid-generating enzyme autotaxin in lymphocyte-endothelial cell interactions. (2008) (113)
Protein tyrosine phosphatase receptor-type O (PTPRO) exhibits characteristics of a candidate tumor suppressor in human lung cancer. (2004) (113)
Involvement of transcriptional repressor ATF3 in acceleration of caspase protease activation during DNA damaging agent‐induced apoptosis (2001) (112)
Conserved BRCT regions of TopBP1 and of the tumor suppressor BRCA1 bind strand breaks and termini of DNA (1999) (111)
Requirement of the Caspase-3/CPP32 Protease Cascade for Apoptotic Death following Cytokine Deprivation in Hematopoietic Cells* (1997) (109)
Cleavage and inactivation of antiapoptotic Akt/PKB by caspases during apoptosis (2000) (108)
Distribution of multi-drug resistance-associated P-glycoprotein in normal and neoplastic human tissues. Analysis with 3 monoclonal antibodies recognizing different epitopes of the P-glycoprotein molecule. (1990) (107)
4'-O-tetrahydropyranyladriamycin as a potential new antitumor agent. (1982) (106)
p53-defective tumors with a functional apoptosome-mediated pathway: a new therapeutic target. (2005) (106)
Immunohistochemical detection of the multidrug transport protein P1 70 in human normal tissues and malignant lymphomas (1991) (106)
Molecular cloning and functional analysis of apoxin I, a snake venom-derived apoptosis-inducing factor with L-amino acid oxidase activity. (2000) (103)
Reversal of breast cancer resistance protein-mediated drug resistance by estrogen antagonists and agonists. (2003) (103)
Adriamycin accumulation and metabolism in adriamycin-sensitive and -resistant human ovarian cancer cell lines. (1986) (103)
Staurosporine, a potent inhibitor of C-kinase, enhances drug accumulation in multidrug-resistant cells. (1990) (102)
Characterization of efflux transport of organic anions in a mouse brain capillary endothelial cell line. (1998) (102)
Functional Sialylated O-Glycan to Platelet Aggregation on Aggrus (T1α/Podoplanin) Molecules Expressed in Chinese Hamster Ovary Cells* (2004) (101)
Defects of the apoptotic pathway as therapeutic target against cancer. (2005) (101)
Prevention of phosphatidylinositol 3'-kinase-Akt survival signaling pathway during topotecan-induced apoptosis. (2000) (101)
Identification of genes differentially expressed in B16 murine melanoma sublines with different metastatic potentials. (1996) (99)
The Cleavage of Akt/Protein Kinase B by Death Receptor Signaling Is an Important Event in Detachment-induced Apoptosis* (2001) (98)
Hypoxia up-regulates telomerase activity via mitogen-activated protein kinase signaling in human solid tumor cells. (1999) (98)
Regulation of Kinase Activity of 3-Phosphoinositide-dependent Protein Kinase-1 by Binding to 14-3-3* (2002) (98)
P-Glycoprotein-Mediated Transport of Itraconazole across the Blood-Brain Barrier (1998) (98)
Novel antitumour metabolites produced by a fungal strain from a sea hare (1997) (97)
Inhibition of Multidrug‐resistant Human Tumor Growth in Athymic Mice by Anti‐P‐glycoprotein Monoclonal Antibodies (1989) (97)
Involvement of mitochondrial aggregation in arsenic trioxide (As2O3)‐induced apoptosis in human glioblastoma cells (2005) (97)
Inhibition of P-glycoprotein by orange juice components, polymethoxyflavones in adriamycin-resistant human myelogenous leukemia (K562/ADM) cells. (2000) (97)
Immunohistochemical detection of multidrug resistance associated P-glycoprotein in tumour and stromal cells of human cancers. (1990) (96)
Imaging of caspase‐3 activation in HeLa cells stimulated with etoposide using a novel fluorescent probe (1999) (96)
Topotecan inhibits VEGF‐ and bFGF‐induced vascular endothelial cell migration via downregulation of the PI3K‐Akt signaling pathway (2002) (95)
Sensitivity of multidrug-resistant tumor cell lines to immunologic effector cells. (1996) (95)
Hypoxia up-regulates glyceraldehyde-3-phosphate dehydrogenase in mouse brain capillary endothelial cells: involvement of Na+/Ca2+ exchanger. (2003) (95)
MDR1 gene expression: its effect on drug resistance to doxorubicin in human hepatocellular carcinoma cell lines. (1994) (93)
Reduced sialidase expression in highly metastatic variants of mouse colon adenocarcinoma 26 and retardation of their metastatic ability by sialidase overexpression (2002) (93)
NH2-terminal BH4 Domain of Bcl-2 Is Functional for Heterodimerization with Bax and Inhibition of Apoptosis* (1999) (91)
Role of p53 and p21/WAF1 detection in patient selection for preoperative radiotherapy in rectal cancer patients (1998) (90)
Specialized Localization of P‐Glycoprotein Recognized by MRK 16 Monoclonal Antibody in Endothelial Cells of the Brain and the Spinal Cord (1990) (90)
Involvement of Bcl-2 cleavage in the acceleration of VP-16-induced U937 cell apoptosis. (1998) (90)
Mitochondrial aggregation precedes cytochrome c release from mitochondria during apoptosis (2003) (90)
Transforming Growth Factor-β1 Upregulates the Tight Junction and P-glycoprotein of Brain Microvascular Endothelial Cells (2004) (88)
Efflux of a suppressive neurotransmitter, GABA, across the blood–brain barrier (2001) (88)
Functional Subdomain in the Ankyrin Domain of Tankyrase 1 Required for Poly(ADP-Ribosyl)ation of TRF1 and Telomere Elongation (2004) (87)
Immunohistochemical identification of P-glycoprotein in previously untreated, diffuse large cell and immunoblastic lymphomas. (1992) (86)
Estrone and 17β‐Estradiol Reverse Breast Cancer Resistance Protein‐mediated Multidrug Resistance (2002) (86)
Platelet aggregation in the formation of tumor metastasis. (2008) (85)
Soluble FLT-1 expression suppresses carcinomatous ascites in nude mice bearing ovarian cancer. (2002) (84)
In vivo detection of multidrug-resistant (MDR1) phenotype by technetium-99m sestamibi scan in untreated breast cancer patients (1997) (84)
Structure-activity relationship of newly synthesized quinoline derivatives for reversal of multidrug resistance in cancer. (1997) (83)
P-glycoprotein expression in primary breast cancer detected by immunocytochemistry with two monoclonal antibodies. (1990) (83)
3-Phosphoinositide-dependent Protein Kinase-1-mediated IκB Kinase β (IKKB) Phosphorylation Activates NF-κB Signaling* (2005) (82)
Human recombinant interferons‐beta and ‐gamma decrease gelatinase production and invasion by human KG‐2 renal‐carcinoma cells (1994) (81)
Critical involvement of the phosphatidylinositol 3-kinase/Akt pathway in anchorage-independent growth and hematogeneous intrahepatic metastasis of liver cancer. (2002) (80)
Human Intestinal Epithelial Cell Survival and Anoikis (2004) (80)
Detection of multidrug resistance markers, P-glycoprotein and mdr1 mRNA, in human leukemia cells. (1987) (80)
β1 integrin/Fak/Src signaling in intestinal epithelial crypt cell survival: integration of complex regulatory mechanisms (2008) (79)
Multidrug resistance after retroviral transfer of the human MDR1 gene correlates with P-glycoprotein density in the plasma membrane and is not affected by cytotoxic selection. (1991) (79)
Novel metastasis model of human lung cancer in SCID mice depleted of NK cells (1996) (79)
Transforming Growth Factor-β Induces Expression of Receptor Activator of NF-κB Ligand in Vascular Endothelial Cells Derived from Bone* (2002) (79)
Glucose-regulated stresses confer resistance to VP-16 in human cancer cells through a decreased expression of DNA topoisomerase II. (1995) (79)
Reversal of drug resistance in a human colon cancer xenograft expressing MDR1 complementary DNA by in vivo administration of MRK-16 monoclonal antibody. (1991) (79)
Biodistribution and ultrastructural localization of single-walled carbon nanohorns determined in vivo with embedded Gd2O3 labels. (2009) (78)
Activation of actin-cleavable interleukin 1beta-converting enzyme (ICE) family protease CPP-32 during chemotherapeutic agent-induced apoptosis in ovarian carcinoma cells. (1996) (78)
Expression of the MDR1 gene in human gastric and colorectal carcinomas. (1990) (77)
Dofequidar fumarate sensitizes cancer stem‐like side population cells to chemotherapeutic drugs by inhibiting ABCG2/BCRP‐mediated drug export (2009) (77)
DT-diaphorase as a critical determinant of sensitivity to mitomycin C in human colon and gastric carcinoma cell lines. (1996) (76)
DNA-mediated transfer and cloning of a human multidrug-resistant gene of adriamycin-resistant myelogenous leukemia K562. (1987) (76)
Bioactive cardenolides from the stems and twigs of Nerium oleander. (2007) (76)
High calcium content of pleiotropic drug-resistant P388 and K562 leukemia and Chinese hamster ovary cells. (1984) (74)
Transport of cyclosporin A across the brain capillary endothelial cell monolayer by P-glycoprotein. (1994) (74)
FOXO transcription factor-dependent p15INK4b and p19INK4d expression (2008) (74)
Antitumor effect of CPT-11, a new derivative of camptothecin, against pleiotropic drug-resistant tumors in vitro and in vivo (2004) (73)
Tetraspanin family member CD9 inhibits Aggrus/podoplanin-induced platelet aggregation and suppresses pulmonary metastasis. (2008) (73)
Dofequidar fumarate (MS-209) in combination with cyclophosphamide, doxorubicin, and fluorouracil for patients with advanced or recurrent breast cancer. (2007) (73)
Evaluation of Antivascular and Antimitotic Effects of Tubulin Binding Agents in Solid Tumor Therapy (1999) (72)
Nucleobindin 1 Controls the Unfolded Protein Response by Inhibiting ATF6 Activation* (2007) (72)
PRMT5, a Novel TRAIL Receptor-Binding Protein, Inhibits TRAIL-Induced Apoptosis via Nuclear Factor-κB Activation (2009) (72)
Binding properties of monoclonal antibodies recognizing external epitopes of the human MDR1 P‐glycoprotein (1993) (72)
Preferential expression and activity of multidrug resistance gene 1 product (P-glycoprotein), a functionally active efflux pump, in human CD8 + T cells: A role in cytotoxic effector function (1992) (71)
Steroid hormones inhibit binding of Vinca alkaloid to multidrug resistance related P-glycoprotein. (1989) (71)
The BRCT regions of tumor suppressor BRCA1 and of XRCC1 show DNA end binding activity with a multimerizing feature. (2000) (69)
Increased expression of thioredoxin/adult T-cell leukemia-derived factor in cisplatin-resistant human cancer cell lines. (1996) (68)
Synthesis and antitumor activity of fused tetracyclic quinoline derivatives. 1. (1989) (68)
Apparent stronger expression in the human adrenal cortex than in the human adrenal medulla of Mr 170,000-180,000 P-glycoprotein. (1988) (67)
Enhancement of L-cystine transport activity and its relation to xCT gene induction at the blood-brain barrier by diethyl maleate treatment. (2002) (67)
Identification of a platelet-aggregating factor of murine colon adenocarcinoma 26: Mr 44,000 membrane protein as determined by monoclonal antibodies. (1988) (66)
Taxuspines A ∼ C, new taxoids from Japanese yew Taxus cuspidata inhibiting drug transport activity of P-glycoprotein in multidrug-resistant cells (1994) (65)
Overexpression of multidrug resistance‐associated p170‐glycoprotein in acute non‐lymphocytic leukemia (1992) (65)
Cullin 3 Promotes Proteasomal Degradation of the Topoisomerase I-DNA Covalent Complex (2004) (64)
Intestinal epithelial cancer cell anoikis resistance: EGFR‐mediated sustained activation of Src overrides Fak‐dependent signaling to MEK/Erk and/or PI3‐K/Akt‐1 (2009) (64)
Basic fibroblast growth factor induces cyclooxygenase-2 expression in endothelial cells derived from bone. (1999) (64)
Casein kinase 2-interacting protein-1, a novel Akt pleckstrin homology domain-interacting protein, down-regulates PI3K/Akt signaling and suppresses tumor growth in vivo. (2007) (63)
Effect of cyclosporin A or tacrolimus on the function of blood-brain barrier cells. (1999) (63)
Relation between thymidylate synthase expression and survival in colon carcinoma, and determination of appropriate application of 5-fluorouracil by immunohistochemical method (2000) (63)
GSH Transport in Immortalized Mouse Brain Endothelial Cells (1999) (62)
Enhancement of cellular accumulation of cyclosporine by anti-P-glycoprotein monoclonal antibody MRK-16 and synergistic modulation of multidrug resistance. (1993) (62)
Purification of the Mr 22,000 calcium-binding protein (sorcin) associated with multidrug resistance and its detection with monoclonal antibodies. (1988) (62)
Induction of apoptosis in mouse brain capillary endothelial cells by cyclosporin A and tacrolimus. (2000) (61)
Suppression of experimental lung colonization of a metastatic variant of murine colon adenocarcinoma 26 by a monoclonal antibody 8F11 inhibiting tumor cell-induced platelet aggregation. (1991) (61)
Involvement of FKHR-Dependent TRADD Expression in Chemotherapeutic Drug-Induced Apoptosis (2002) (61)
Freud-1/Aki1, a Novel PDK1-Interacting Protein, Functions as a Scaffold To Activate the PDK1/Akt Pathway in Epidermal Growth Factor Signaling (2008) (61)
Modulation of multidrug resistance by verapamil or mdr1 anti‐sense oligodeoxynucleotide does not change the high susceptibility to lymphokine‐activated killers in mdr‐resistant human carcinoma (LoVo) line (1990) (61)
Promotion of glioma cell survival by acyl-CoA synthetase 5 under extracellular acidosis conditions (2009) (60)
In vivo circumvention of vincristine resistance in mice with P388 leukemia using a novel compound, AHC-52. (1989) (60)
Human intestinal epithelial crypt cell survival and death: Complex modulations of Bcl‐2 homologs by Fak, PI3‐K/Akt‐1, MEK/Erk, and p38 signaling pathways (2004) (60)
High expression of the multidrug resistance P-glycoprotein in high-risk myelodysplasia is associated with immature phenotype. (1993) (59)
Drug resistance in chemotherapy for breast cancer (2005) (59)
Expression of P-glycoprotein in de novo acute myelogenous leukemia at initial diagnosis: results of molecular and functional assays, and correlation with treatment outcome. (1994) (59)
SUMO-1 conjugation to intact DNA topoisomerase I amplifies cleavable complex formation induced by camptothecin (2002) (59)
Acyl‐CoA synthetase as a cancer survival factor: its inhibition enhances the efficacy of etoposide (2009) (58)
Overexpression of the csk gene suppresses tumor metastasis in vivo (2000) (58)
Prediction of Sensitivity to STI571 among Chronic Myeloid Leukemia Patients by Genome‐wide cDNA Microarray Analysis (2002) (58)
CXCL13 is an arrest chemokine for B cells in high endothelial venules. (2005) (57)
HtrA2 cleaves Apollon and induces cell death by IAP-binding motif in Apollon-deficient cells. (2005) (56)
A Novel Combretastatin A‐4 Derivative, AC‐7700, Shows Marked Antitumor Activity against Advanced Solid Tumors and Orthotopically Transplanted Tumors (1999) (56)
Expression of platelet‐derived endothelial cell growth factor correlates with good prognosis in patients with colorectal carcinoma (2000) (55)
Inhibitory effects of n-3 polyunsaturated fatty acids on sigmoid colon cancer transformants (1998) (55)
Expression of the multiple drug resistance gene (mdr‐1) and epitope masking in chronic lymphatic leukaemia (1990) (55)
Suppression of Interleukin‐11–mediated bone resorption by cyclooxygenases inhibitors (1998) (55)
Antitumor activity and novel DNA‐self‐strand‐breaking mechanism of CNDAC (1‐(2‐C‐cyano‐2‐deoxy‐β‐d‐ARABINO‐Pentofuranosyl) cytosine) and its N4‐palmitoyl derivative (CS‐682) (1999) (55)
Increase of daunorubicin and vincristine accumulation in multidrug resistant human ovarian carcinoma cells by a monoclonal antibody reacting with P-glycoprotein. (1988) (54)
Differentiation of Lymphatic Endothelial Cells From Embryonic Stem Cells on OP9 Stromal Cells (2006) (54)
Inhibitory Effect of ATF3 Antisense Oligonucleotide on Ectopic Growth of HT29 Human Colon Cancer Cells (2000) (54)
Inhibition of P-glycoprotein by flavonoid derivatives in adriamycin-resistant human myelogenous leukemia (K562/ADM) cells. (2002) (53)
Production of interleukin-11 in bone-derived endothelial cells and its role in the formation of osteolytic bone metastasis (1998) (53)
MX2, a morpholino anthracycline, as a new antitumor agent against drug-sensitive and multidrug-resistant human and murine tumor cells. (1988) (52)
Abnormal expression of a 170-kilodalton P-glycoprotein encoded by MDR1 gene, a metabolically active efflux pump, in CD4+ and CD8+ T cells from patients with human immunodeficiency virus type 1 infection. (1996) (52)
Immunological Quantitation of DT‐Diaphorase in Carcinoma Cell Lines and Clinical Colon Cancers: Advanced Tumors Express Greater Levels of DT‐Diaphorase (1998) (52)
Cytotoxicity and Antitumor Activities of Fungal Bis (naphtho-γ-pyrone) Derivatives (1988) (52)
p27Kip1 localization depends on the tumor suppressor protein tuberin. (2007) (51)
Inhibition of P-glycoprotein and recovery of drug sensitivity of human acute leukemic blast cells by multidrug resistance gene (mdr1) antisense oligonucleotides. (1998) (51)
Regulation of Gelatinase Production in Metastatic Renal Cell Carcinoma by Organ‐specific Fibroblasts (1994) (51)
Synthesis and anti-HIV activity of 9-[c-4,t-5-bis(hydroxymethyl)cyclopent-2-en-r-1-yl]-9H-adenine. (1992) (51)
Combined therapy of multidrug‐resistant human lung cancer with anti‐P‐glycoprotein antibody and monocyte chemoattractant protein‐1 gene transduction: The possibility of immunological overcoming of multidrug resistance (1997) (50)
Pim-1 negatively regulates the activity of PTP-U2S phosphatase and influences terminal differentiation and apoptosis of monoblastoid leukemia cells. (2001) (50)
Characterization of dihydropyrimidine dehydrogenase on immunohistochemistry in colon carcinoma, and correlation between immunohistochemical score and protein level or messenger RNA expression. (2000) (50)
Nuclear localization of proteasomes participates in stress-inducible resistance of solid tumor cells to topoisomerase II-directed drugs. (2002) (50)
Direct interaction between a quinoline derivative, MS-209, and multidrug resistance protein (MRP) in human gastric cancer cells. (1999) (50)
Glucose‐regulated stresses induce resistance to camptothecin in human cancer cells (1996) (49)
Development and characterization of a model of liver metastasis using human colon cancer HCT-116 cells. (2007) (49)
Dihydropyrimidine dehydrogenase but not thymidylate synthase expression is associated with resistance to 5-fluorouracil in colorectal cancer. (1998) (49)
Stimulation of interleukin‐11 production from osteoblast‐like cells by transforming growth factor‐β and tumor cell factors (1997) (49)
Bioactive triterpene saponins from the roots of Phytolacca americana. (2008) (49)
P-glycoprotein inhibition by the multidrug resistance-reversing agent MS-209 enhances bioavailability and antitumor efficacy of orally administered paclitaxel (2002) (48)
Circumvention of multidrug resistance by a newly synthesized quinoline derivative, MS-073. (1991) (48)
Specific targeting and killing activities of anti-P-glycoprotein monoclonal antibody MRK16 directed against intrinsically multidrug-resistant human colorectal carcinoma cell lines in the nude mouse model. (1993) (48)
P-glycoprotein expression and in vitro reversion of doxorubicin resistance by verapamil in clinical specimens from acute leukaemia and myeloma. (1991) (47)
Evidence of carrier-mediated transport in the penetration of donepezil into the rat brain. (2010) (47)
c-Myc plays a role in cellular susceptibility to death receptor-mediated and chemotherapy-induced apoptosis in human monocytic leukemia U937 cells (1997) (47)
p21Waf1/cip1 acts in synergy with bcl‐2 to confer multidrug resistance in a camptothecin‐selected human lung‐cancer cell line (1999) (47)
Establishment and properties of vincristine-resistant human myelogenous leukemia K562. (1983) (47)
A phase II study of aclacinomycin A in acute leukemia in adults. (1980) (46)
Enhancement of voltage-gated Na+ channel current associated with multidrug resistance in human leukemia cells. (1987) (46)
Effects of taxoids from Taxus cuspidata on microtubule depolymerization and vincristine accumulation in MDR cells (1997) (45)
Expressions of Cell Cycle Regulators in Human Colorectal Cancer Cell Lines (1997) (45)
Resistance to antitumor agent-induced apoptosis in a mutant of human myeloid leukemia U937 cells. (1994) (45)
Possibility of the reversal of multidrug resistance and the avoidance of side effects by liposomes modified with MRK-16, a monoclonal antibody to P-glycoprotein. (2001) (45)
Altered Expression and Function of P-Glycoprotein (170 Kda), Encoded by the MDR 1 Gene, in T Cell Subsets from Aging Humans (1997) (45)
Establishment and characterization of doxorubicin-resistant human bladder cancer cell line, KK47/ADM. (1992) (44)
Synthesis and antitumor activity of tropolone derivatives. 6. Structure-activity relationships of antitumor-active tropolone and 8-hydroxyquinoline derivatives. (1987) (44)
MS-209, a quinoline-type reversal agent, potentiates antitumor efficacy of docetaxel in multidrug-resistant solid tumor xenograft models. (2002) (44)
Decreased expression of the amplified mdr1 gene in revertants of multidrug-resistant human myelogenous leukemia K562 occurs without loss of amplified DNA (1987) (43)
IL12RB2 and ABCA1 Genes Are Associated with Susceptibility to Radiation Dermatitis (2008) (43)
Cloning, expression and chromosomal localization of a novel gene for protein tyrosine phosphatase (PTP-U2) induced by various differentiation-inducing agents. (1995) (43)
High-affinity efflux transport system for glutathione conjugates on the luminal membrane of a mouse brain capillary endothelial cell line (MBEC4). (1999) (42)
Down‐regulation of epidermal growth factor receptor‐signaling pathway by binding of GRP78/BiP to the receptor under glucose‐starved stress conditions (1998) (42)
Stabilization of integrin-linked kinase by binding to Hsp90. (2005) (42)
Mitochondria regulate the unfolded protein response leading to cancer cell survival under glucose deprivation conditions (2010) (42)
Cellular sensitization to cisplatin and carboplatin with decreased removal of platinum-DNA adduct by glucose-regulated stress (1999) (42)
Glyoxalase-I is a novel target against Bcr-Abl+ leukemic cells acquiring stem-like characteristics in a hypoxic environment (2010) (41)
Molecular cancer therapeutics: recent progress and targets in drug resistance. (2003) (41)
Cellular FLIP Inhibits β-Catenin Ubiquitylation and Enhances Wnt Signaling (2004) (41)
Role of protein kinase C in the modulation of multidrug resistance: expression of the atypical gamma isoform of protein kinase C does not confer increased resistance to doxorubicin. (1992) (41)
Purification and characterization of the platelet-aggregating sialoglycoprotein gp44 expressed by highly metastatic variant cells of mouse colon adenocarcinoma 26. (1995) (41)
Role of ABC Transporters in Aureobasidin A Resistance (1998) (41)
Induction of hepatic P-glycoprotein enhances biliary excretion of vincristine in rats. (1995) (41)
Effects of Various Methoxyflavones on Vincristine Uptake and Multidrug Resistance to Vincristine in P-gp-Overexpressing K562/ADM Cells (2007) (39)
Inhibition of tumor cell invasion and matrix degradation by aminopeptidase inhibitors. (1996) (39)
Potentiation of chemotherapeutic effect of vincristine in vincristine resistant tumor bearing mice by calmodulin inhibitor clomipramine. (1983) (39)
Regression of established tumors expressing P-glycoprotein by combinations of adriamycin, cyclosporin derivatives, and MRK-16 antibodies. (1997) (39)
Treatment of children with refractory acute lymphocytic leukemia with vincristine and diltiazem. (1985) (39)
Purification and characterization of NF-R1 that regulates the expression of the human multidrug resistance (MDR1) gene. (1992) (38)
Isolation of murine and human homologues of the fission-yeast dis3+ gene encoding a mitotic-control protein and its overexpression in cancer cells with progressive phenotype. (1997) (38)
Prevention of carbon nanohorn agglomeration using a conjugate composed of comb-shaped polyethylene glycol and a peptide aptamer. (2009) (38)
Interaction of cyclosporin derivatives with the ATPase activity of human P‐glycoprotein (1997) (38)
Cellular pharmacology of MX2, a new morpholino anthracycline, in human pleiotropic drug-resistant cells. (1991) (38)
Enhanced expression by the brain matrix of P-glycoprotein in brain capillary endothelial cells. (1994) (38)
Glucose‐regulated protein 78: A new partner of p53 in trophoblast (2009) (37)
Bioactive lignans from Peperomia duclouxii. (2007) (37)
Transforming growth factor-beta induces expression of receptor activator of NF-kappa B ligand in vascular endothelial cells derived from bone. (2002) (36)
p21Waf1/Cip1 Expression Is a Prognostic Marker in Curatively Resected Esophageal Squamous Cell Carcinoma, but Not p27Kip1, p53, or Rb (1999) (36)
Antitumor Activity of 7-N-{{2-{[2-(γ-l-Glutamylamino)ethyl]dithio}ethyl}}-mitomycin C (1991) (36)
Potentiation of the reversal activity of SDZ PSC833 on multi‐drug resistance by an anti‐p‐glycoprotein monoclonal antibody MRK‐16 (1996) (36)
Mouse-human chimeric antibody against the multidrug transporter P-glycoprotein. (1990) (36)
3-Phosphoinositide-dependent protein kinase-1-mediated IkappaB kinase beta (IkkB) phosphorylation activates NF-kappaB signaling. (2005) (36)
Comparison of cytotoxic effect and cellular uptake of 1-beta-D-arabinofuranosylcytosine and its N4-acyl derivatives, using cultured KB cells. (1979) (36)
Differential expression of DNA topoisomerase I gene between CPT-11 acquired- and native-resistant human pancreatic tumor cell lines: detected by RNA/PCR-based quantitation assay. (1992) (36)
Reversal of multidrug resistance by a novel quinoline derivative, MS-209 (1995) (36)
C 421 A Polymorphism in the Human Breast Cancer Resistance Protein Gene Is Associated with Low Expression of Q 141 K Protein and Low-Level Drug Resistance 1 (2002) (36)
Expression of a Mr 41,000 glycoprotein associated with thrombin-independent platelet aggregation in high metastatic variants of murine B16 melanoma. (1990) (35)
Ultrastructural localization of P-glycoprotein on capillary endothelial cells in human gliomas (2004) (35)
Transforming growth factor-beta1 upregulates the tight junction and P-glycoprotein of brain microvascular endothelial cells. (2004) (35)
Chemosensitisation by manganese superoxide dismutase inhibition is caspase-9 dependent and involves extracellular signal-regulated kinase 1/2 (2008) (35)
Glucose starvation and hypoxia induce nuclear accumulation of proteasome in cancer cells. (1999) (35)
An Inhibitory Role of Nitric Oxide in the Dynamic Regulation of the Blood-Brain Barrier Function (2007) (35)
Monoclonal Anti‐P‐glycoprotein Antibody‐dependent Killing of Multidrug‐resistant Tumor Cells by Human Mononuclear Cells (1990) (35)
Bioactive tetrahydrofuran lignans from Peperomia dindygulensis. (2005) (35)
Synthesis and antitumor activity of tropolone derivatives. 7. Bistropolones containing connecting methylene chains. (1992) (34)
Acquisition of metastatic ability in hybridomas between two low metastatic clones of murine colon adenocarcinoma 26 defective in either platelet-aggregating activity or in vivo growth potential. (1987) (34)
A novel quinoline derivative, MS-209, overcomes drug resistance of human lung cancer cells expressing the multidrug resistance-associated protein (MRP) gene (1997) (34)
Interaction between Glucose-regulated Destruction Domain of DNA Topoisomerase IIα and MPN Domain of Jab1/CSN5* (2004) (34)
Bispecific antibodies reactive with the multidrug‐resistance‐related glycoprotein and CD3 induce lysis of multidrug‐resistant tumor cells (1989) (34)
Comparative evaluation of S9788, verapamil, and cyclosporine A in K562 human leukemia cell lines and in P-glycoprotein-expressing samples from patients with hematologic malignancies. (1994) (34)
Activation of c-Abl tyrosine kinase requires caspase activation and is not involved in JNK/SAPK activation during apoptosis of human monocytic leukemia U937 cells (1999) (34)
Modulation of Wnt signaling by the nuclear localization of cellular FLIP-L (2010) (34)
TUSC4/NPRL2, a novel PDK1‐interacting protein, inhibits PDK1 tyrosine phosphorylation and its downstream signaling (2008) (33)
Glucose-regulated stresses cause decreased expression of cyclin D1 and hypophosphorylation of retinoblastoma protein in human cancer cells. (1996) (33)
Variable effects of sodium butyrate on the expression and function of the MDR 1 (P‐glycoprotein) gene in colon carcinoma cell lines (1993) (33)
Monoclonal antibodies specific for P-glycoprotein (1997) (33)
SATURABLE DISTRIBUTION OF TACRINE INTO THE STRIATAL EXTRACELLULAR FLUID OF THE RAT: EVIDENCE OF INVOLVEMENT OF MULTIPLE ORGANIC CATION TRANSPORTERS IN THE TRANSPORT (2005) (33)
Antitumor activity of a spicamycin derivative, KRN5500, and its active metabolite in tumor cells. (1994) (33)
In vivo delivery of glial cell-derived neurotrophic factor across the blood-brain barrier by gene transfer into brain capillary endothelial cells. (2003) (33)
Efflux Transport of Tolbutamide Across the Blood‐brain Barrier (1998) (32)
Structure-antitumor activity relationship of semi-synthetic spicamycin analogues. (1993) (32)
Cross‐species difference in telomeric function of tankyrase 1 (2007) (32)
Choline Uptake by Mouse Brain Capillary Endothelial Cells in Culture (1999) (32)
Functionally active homodimer of P-glycoprotein in multidrug-resistant tumor cells. (1992) (32)
Absolute structure-cytotoxic activity relationships of steganacin congeners and analogues. (1991) (32)
Mr 85,000 membrane protein specifically expressed in adriamycin-resistant human tumor cells. (1988) (32)
A Novel Endoplasmic Reticulum Export Signal (2009) (32)
Inhibition of spontaneous and experimental metastasis by a new derivative of camptothecin, CPT-11, in mice (2004) (31)
Low metastatic potential of clone from murine colon adenocarcinoma 26 increased by transfection of activated c-erbB-2 gene. (1990) (31)
Synthesis and antitumor activity of tropolone derivatives. (1984) (31)
Mycobacterium tuberculosis induces expression of P-glycoprotein in promonocytic U1 cells chronically infected with HIV type 1. (1994) (30)
Hypoxic up-regulation of triosephosphate isomerase expression in mouse brain capillary endothelial cells. (2004) (30)
Human ovarian cancer cell lines resistant to cisplatin, doxorubicin, and l-phenylalanine mustard are sensitive to Δ7-prostaglandin Δ1 and Δ12-prostaglandin J2 (1991) (30)
Functional Interaction of DNA Topoisomerase IIα With the β-Catenin and T-Cell Factor-4 Complex (2007) (30)
Isolation and characterization of highly and rarely metastatic clones from murine colon adenocarcinoma 26. (1984) (30)
Expression and function of multidrug resistance P-glycoprotein in a cultured natural killer cell-rich population revealed by MRK16 monoclonal antibody and AHC-52. (1994) (30)
Adenovirus deoxyribonucleic acid replication. Characterization of the enzyme activities of a soluble replication system. (1977) (30)
Suppression of T-lymphoma cell apoptosis by monoclonal antibodies raised against cell surface adhesion molecules. (1993) (30)
TRF1 mediates mitotic abnormalities induced by Aurora-A overexpression. (2010) (29)
Tumor-induced platelet aggregation and growth promoting factors as determinants for successful tumor metastasis (2004) (29)
Synthesis and antitumor activity of fused quinoline derivatives. (1990) (29)
Cremophor EL reversed multidrug resistance in vitro but not in tumor-bearing mouse models (1996) (29)
Cellular and Tissue Distribution of MRK20 Murine Monoclonal Antibody‐defined 85‐kDa Protein in Adriamycin‐resistant Cancer Cell Lines*1 (1988) (29)
Contribution of P‐glycoprotein to efflux of ramosetron, a 5‐HT3 receptor antagonist, across the blood‐brain barrier (2002) (29)
Decreased Synthesis of Matrix Metalloproteinase-7 and Adhesion to the Extracellular Matrix Proteins of Human Colon Cancer Cells Treated with Troglitazone (2002) (29)
Modulation of multidrug resistance by taxuspine C and other taxoids from Japanese yew. (1998) (29)
Preventing the unfolded protein response via aberrant activation of 4E‐binding protein 1 by versipelostatin (2009) (29)
Interleukin-7 inhibits apoptosis of mouse malignant T-lymphoma cells by both suppressing the CPP32-like protease activation and inducing the Bcl-2 expression. (1996) (29)
Elimination of chemoresistant multiple myeloma clonogenic colony-forming cells by combined treatment with a plasma cell-reactive monoclonal antibody and a P-glycoprotein-reactive monoclonal antibody. (1989) (29)
Inhibition of lymph node metastasis of P388 leukemia by bestatin in mice. (1981) (28)
Control of apoptosis and growth of malignant T lymphoma cells by lymph node stromal cells. (1993) (28)
Taxoids and abietanes from callus cultures of Taxus cuspidata. (2005) (28)
Cross-resistance to anti-HIV nucleoside analogs in multidrug-resistant human cells. (1990) (28)
Reversal of multidrug resistance by an immunosuppressive agent FK-506 (2004) (28)
Two populations of Thy1-positive mesenchymal cells regulate in vitro maturation of hepatic progenitor cells. (2007) (28)
Inhibition of Transforming Growth Factor-β Production in Brain Pericytes Contributes to Cyclosporin A-Induced Dysfunction of the Blood-Brain Barrier (2007) (27)
Group IID heparin-binding secretory phospholipase A(2) is expressed in human colon carcinoma cells and human mast cells and up-regulated in mouse inflammatory tissues. (2002) (27)
Uptake and Efflux of Quinacrine, a Candidate for the Treatment of Prion Diseases, at the Blood-Brain Barrier (2004) (27)
Collateral susceptibility of adriamycin-, melphalan- and cisplatin-resistant human ovarian tumor cells to bleomycin. (1986) (27)
Cellular FLIP inhibits beta-catenin ubiquitylation and enhances Wnt signaling. (2004) (27)
Binding diversity of antibodies against external and internal epitopes of the multidrug resistance gene product P-glycoprotein. (1995) (26)
Coexpression of a multidrug resistance gene (MDR1) and herpes simplex virus thymidine kinase gene in a bicistronic retroviral vector Ha-MDR-IRES-TK allows selective killing of MDR1-transduced human tumors transplanted in nude mice. (1997) (26)
Cure of mice bearing P388 leukemia by vincristine in combination with a calcium channel blocker. (1985) (26)
High-level expression of MRK 16 and MRK 20 murine monoclonal antibody-define proteins (170,000-180,000 P-glycoprotein and 85,000 protein) in leukaemias and malignant lymphomas. (1989) (26)
A BRIEF HISTORY OF CANCER CHEMOTHERAPY (2002) (26)
Nitric oxide mediates cyclosporine-induced impairment of the blood-brain barrier in cocultures of mouse brain endothelial cells and rat astrocytes. (2004) (26)
Clustered cancer cells show a distinct adhesion behavior from single cell form under physiological shear conditions. (2001) (26)
Establishment of a daunorubicin-resistant cell line which shows multi-drug resistance by multifactorial mechanisms. (1996) (25)
Determination of membrane antigens by a covalent crosslinking method with monoclonal antibodies. (1987) (25)
Suppression of experimental lung colonization of mouse colon adenocarcinoma 26 in vivo by an anti-idiotype monoclonal antibody recognizing a platelet surface molecule. (1997) (25)
Reversal of Multidrug Resistance by Calcium Channel Blockers and Other Agents (1991) (25)
Differential expression of protein tyrosine phosphatase genes during phorbol ester-induced differentiation of human leukemia U937 cells. (1993) (25)
Glucose‐regulated stresses cause degradation of DNA topoisomerase IIα by inducing nuclear proteasome during G1 cell cycle arrest in cancer cells (1999) (25)
Impairment of the ubiquitin‐proteasome system by cellular FLIP (2007) (25)
Furanonaphthoquinone analogs possessing preferential antitumor activity compared to normal cells. (1999) (25)
Absolute stereochemistry and antitumor activity of iejimalides. (2006) (24)
Survival-signaling pathway as a promising target for cancer chemotherapy (2003) (24)
Lymph node metastasis and effects of 1-beta-D-arabinofuranosylcytosine, 5-fluorouracil, and their lipophilic derivatives in an experimental model system using P388 leukemia. (1980) (24)
Functional Involvement of PTP-U2L in Apoptosis Subsequent to Terminal Differentiation of Monoblastoid Leukemia Cells* (1998) (24)
Reversal of adriamycin resistance by recombinant alpha-interferon in multidrug-resistant human colon carcinoma LoVo-doxorubicin cells. (1991) (24)
Multidrug Resistance in Cultured Human Leukemia and Lymphoma Cell Lines Detected by a Monoclonal Antibody, MRK16 (1989) (24)
Potentiation of the antitumor activity by a novel quinoline compound, MS-209, in multidrug-resistant solid tumor cell lines. (1997) (24)
Involvement of Glial Cells in Cyclosporine-Increased Permeability of Brain Endothelial Cells (2000) (24)
Efficient protection of cells from the genotoxicity of nitrosoureas by the retrovirus-mediated transfer of human O6-methylguanine-DNA methyltransferase using bicistronic vectors with human multidrug resistance gene 1. (1998) (24)
Up‐regulation of p27Kip1 Correlates Inversely with Anchorage‐independent Growth of Human Cancer Cell Lines (1998) (23)
Production of biologically active taxoids by a callus culture of Taxus cuspidata. (2004) (23)
On the benzylation of nucleosides. II. A novel synthesis of 2'-o-benzyluridine. (1968) (23)
Inhibition of the association with nuclear matrix of pRB, p70 and p40 proteins along with the specific suppression of c-MYC expression by geldanamycin, an inhibitor of Src tyrosine kinase. (1995) (23)
H-31 human breast cancer cells stimulate type I collagenase production in osteoblast-like cells and induce bone resorption (1995) (23)
Effects of cytochalasins and colchicine on the accumulation and retention of daunomycin and vincristine in drug resistant tumor cells. (1986) (23)
2‐deoxyglucose inhibits chemotheapeutic drug‐induced apoptosis in human monocytic leukemia U937 cells ith inhibition of c‐Jun N‐terminal kinase 1/stress‐activated protein kinase activation (1998) (23)
Inhibition by erythroid differentiation factor (activin A) of P-glycoprotein expression in multidrug-resistant human K562 erythroleukemia cells. (1991) (23)
In vivo and in vitro evidence of blood-brain barrier transport of a novel cationic arginine-vasopressin fragment 4-9 analog. (1999) (23)
A novel anti‐Thy‐1 (CD90) monoclonal antibody induces apoptosis in mouse malignant T‐lymphoma cells in spite of inducing bcl‐2 expression (1996) (22)
Overexpression of thioredoxin does not confer resistance to cisplatin in transfected human ovarian and colon cancer cell lines (1997) (22)
Stimulation of the Growth of Metastatic Clones of Mouse Colon Adenocarcinoma 26 in vitro by Platelet‐derived Growth Factor (1989) (22)
Adverse Effect of Cyclosporin A on Barrier Functions of Cerebral Microvascular Endothelial Cells After Hypoxia-reoxygenation Damage In Vitro (2007) (22)
Improved flow-cytometric detection of low P-glycoprotein expression in leukaemic blasts by histogram subtraction analysis. (1994) (22)
Phorbol ester-resistant monoblastoid leukemia cells with a functional mitogen-activated protein kinase cascade but without responsive protein tyrosine phosphatases. (1995) (22)
Characteristics of vincristine resistance in vincristine resistant human myelogenous leukemia K562. (1986) (22)
Expression of the MDR1 and MDR3 gene products in acute and chronic leukemias. (1997) (22)
M‐CSF gene transduction in multidrug‐resistant human cancer cells to enhance anti‐P‐glycoprotein antibody‐dependent macrophage‐mediated cytotoxicity (1993) (21)
New multidrug-resistance-reversing drugs, MS-209 and SDZ PSC 833 (1997) (21)
Establishment of multidrug resistant human colorectal carcinoma HCT-15 cell lines and their properties. (1991) (21)
Reactivity of P-glycoprotein monoclonal antibodies in childhood cancers. (1992) (21)
A recessive mutant of the U937 cell line acquired resistance to anti-Fas and anti-p55 tumor necrosis factor receptor antibody-induced apoptosis. (1995) (21)
Aggregation of Thy-1 glycoprotein induces thymocyte apoptosis through activation of CPP32-like proteases. (1997) (21)
Carcinoembryonic antigen mRNA in abdominal cavity as a useful predictor of peritoneal recurrence of gastric cancer with serosal exposure. (2002) (21)
Increased drug accumulation ex vivo with cyclosporin in chronic lymphatic leukemia and its relationship to epitope masking of P-glycoprotein. (1991) (20)
P-glycoprotein expression in normal and reactive bone marrows. (1993) (20)
Retroviral coexpression of two different types of drug resistance genes to protect normal cells from combination chemotherapy. (1997) (20)
Nonenzymatic reductive activation of 7-N-((2-([2-(gamma-L-glutamylamino)ethyl]dithio)ethyl))mitomycin C by thiol molecules: a novel mitomycin C derivative effective on mitomycin C-resistant tumor cells. (1994) (20)
Multidrug resistant gene 1 product in human T cell subsets: role of protein kinase C isoforms and regulation by cyclosporin A. (1992) (20)
Modulation of multidrug resistance in tumor cells by taxinine derivatives. (1999) (20)
Effector Cell Analysis of Human Multidrug‐resistant Cell Killing by Mouse‐Human Chimeric Antibody against P‐Glycoprotein (1992) (20)
Antitumor activity of new morpholino anthracyclines. (1988) (20)
Clonal endothelial cells produce humoral factors that inhibit osteoclast-like cell formation in vitro. (2002) (20)
Candicanoside A, a Novel Cytotoxic Rearranged Cholestane Glycoside from Galtonia candicans (2000) (19)
Anti-tumor effect of N-beta-alanyl-5-S-glutathionyldihydroxyphenylalanine (5-S-GAD), a novel anti-bacterial substance from an insect. (2000) (19)
Drug‐selected co‐expression of P‐glycoprotein and gp91 in vivo from an MDR1‐bicistronic retrovirus vector Ha‐MDR‐IRES‐gp91 (2003) (19)
Bioactive dibenzylbutyrolactone and dibenzylbutanediol lignans from Peperomia duclouxii. (2006) (19)
A fluorine-containing anthracycline (ME2303) as a new antitumor agent against murine and human tumors and their multidrug-resistant sublines. (1989) (19)
Characterization of four doxorubicin adapted human breast cancer cell lines with respect to chemotherapeutic drug sensitivity, drug resistance associated membrane proteins and glutathione transferases. (1993) (19)
Antitumor activity of SPM VIII, a derivative of the nucleoside antibiotic spicamycin, against human tumor xenografts. (1994) (19)
Retroviral expression of a mutant (GLY‐533) human DNA topoisomerase I cDNA confers a dominant form of camptothecin resistance (1999) (19)
Involvement of CD45 in adhesion and suppression of apoptosis of mouse malignant T-lymphoma cells. (1995) (19)
On the benzylation of nucleosides. I. Reaction of uridine with benzyl bromide in the presence of sodium hydride. (1968) (18)
Increased expression of the multidrug‐resistance gene in undifferentiated sarcoma (1990) (18)
Inhibition of spontaneous and experimental tumor metastasis by the calcium antagonist verapamil (2004) (18)
The effect of bisulfite modification on the template activity of DNA for DNA polymerase I. (1974) (18)
N-alkylated 1,4-dihydropyridines: new agents to overcome multidrug resistance. (1995) (18)
The 4 F 2 hc / LAT 1 complex transports L-DOPA across the blood – brain barrier (2000) (18)
cDNA expression cloning of the 85-kDa protein overexpressed in adriamycin-resistant cells. (1993) (18)
Neutral taxoids from Taxus cuspidata as modulators of multidrug-resistant tumor cells. (2000) (18)
Bioactive polyketides from Peperomia duclouxii. (2007) (18)
Functional characterization of adenosine transport across the BBB in mice. (2005) (18)
Recovery of drug sensitivity by MS‐209, a new multidrug resistance‐reversing agent, on acute myelogenous leukaemic blasts and K562 cells resistant to adriamycin cell line (1997) (18)
Synthesis and antitumor activity of tropolone derivatives. 1 (1984) (18)
Identification and Characterization of Three DNA‐binding Proteins on the Promoter of the Human MDRl Gene in Drug‐sensitive and ‐resistant Cells (1991) (17)
In vivo veritas: Bcl-2 and Bcl-X(L)mediate tumor cell resistance to chemotherapy. (2000) (17)
DNA polymerases of ascites hepatoma cells. II. Purification and properties of DNA polymerases from nuclear membrane-chromatin fraction. (1972) (17)
Pharmacokinetic characterization of dehydroevodiamine in the rat brain. (2004) (17)
Inhibition of different steps of the ubiquitin system by cisplatin and aclarubicin. (1992) (17)
p 53-Defective Tumors With a Functional Apoptosome-Mediated Pathway : A New Therapeutic Target (2005) (17)
Involvement of fractin in TGF‐β‐induced apoptosis in oligodendroglial progenitor cells (2009) (17)
Structure-antitumor activity relationship of semi-synthetic Spicamycin derivatives. (1995) (17)
Effect of the antitumor antibiotic neocarzinostatin on DNA synthesis in vitro. (1971) (17)
Prevention of vinblastine-induced cytotoxicity by ruthenium red. (1981) (17)
Difference between the resistance mechanisms of aclacinomycin- and adriamycin-resistant P388 cell lines. (1995) (17)
Inhibitory effects of tumor invasion-inhibiting factor 2 and its conjugate on disseminating tumor cells. (1994) (17)
Mechanism of action of an antifungal antibiotic, RI-331, (S) 2-amino-4-oxo-5-hydroxypentanoic acid; kinetics of inactivation of homoserine dehydrogenase from Saccharomyces cerevisiae. (1992) (17)
Metastasis after intravenous inoculation of highly metastatic variants of mouse tumors and the effects of several antitumor drugs on the tumors. (1984) (16)
Insulin-like growth factor I rapidly induces tyrosine phosphorylation of a Mr 150,000 and a Mr 160,000 protein in highly metastatic mouse colon carcinoma 26 NL-17 cells. (1991) (16)
Further Characterization of the Human Adrenal‐derived P‐GIycoprotein Recognized by Monoclonal Antibody MRK 16 Reacting with Only Human P‐Glycoprotein (1989) (16)
Expression of P‐Glycoprotein mRNA in Human Gastric Tumors (1989) (16)
Monocyte chemoattractant protein‐1 gene modification of multidrug‐resistant human lung cancer enhances antimetastatic effect of therapy with anti‐P‐glycoprotein antibody in SCID mice (1999) (16)
Pilot study of MDR1 gene transfer into hematopoietic stem cells and chemoprotection in metastatic breast cancer patients (2007) (16)
A novel anti-platelet monoclonal antibody induces mouse platelet aggregation through an Fc receptor-independent mechanism. (1998) (16)
Purification and Characterization of NF‐R2 that Regulates the Expression of the Human Multidrug Resistance (MDR1) Gene (1993) (16)
Magnetic-affinity cell sorting of human multidrug-resistant cells. (1991) (16)
Human immunodeficiency virus type 1 induces 1-beta-D-arabinofuranosylcytosine resistance in human H9 cell line. (1992) (16)
Contribution of P‐glycoprotein to bunitrolol efflux across blood–brain barrier (1999) (15)
Overexpression of the csk gene suppresses tumor metastasis in vivo. (2000) (15)
Comparison of glutathione S-transferase activity between drug-resistant and-sensitive human tumor cells: Is glutathione S-transferase associated with multidrug resistance? (2004) (15)
Immunocytochemical Identification and Localization of the Mr 22,000 Calcium‐binding Protein (Sorcin) in an Adriamycin‐resistant Myelogenous Leukemia Cell Line (1989) (15)
Chromosome 22 complements apoptosis in Fas-and TNF-resistant mutant UK110 cells. (1996) (15)
Evaluation of antitumor activity of navelbine (vinorelbine ditartrate) against human breast carcinoma xenografts based on its pharmacokinetics in nude mice (1994) (15)
Reconstitution of Caspase-3 Confers Low Glucose-Enhanced Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Cytotoxicity and Akt Cleavage (2004) (15)
Telomere elongation by a mutant tankyrase 1 without TRF1 poly(ADP-ribosyl)ation. (2008) (15)
Expression of carbohydrate-binding protein p33/41 in human tumor cell lines. (1996) (15)
Mode of Binding of Anti-P-glycoprotein Antibody MRK-16 to Its Antigen (1998) (15)
Galtonioside A, a novel cytotoxic cholestane glycoside from Galtonia candicans (2000) (15)
Potentiation of antitumor agents by calcium channel blockers with special reference to cross-resistance patterns (2004) (15)
Purification and further characterization of three DNA polymerases of rat Ascites hepatoma cells. (1974) (15)
Circumvention of multidrug resistance by a quinoline derivative, MS-209, in multidrug-resistant human small-cell lung cancer cells and its synergistic interaction with cyclosporin A or verapamil (1998) (15)
A New Quinoline Derivative MS‐209 Reverses Multidrug Resistance and Inhibits Multiorgan Metastases by P‐glycoprotein‐expressing Human Small Cell Lung Cancer Cells (2001) (15)
Cytotoxicity and antitumor activities of fungal bis(naphtho-gamma-pyrone) derivatives. (1988) (15)
Transluminal Gene Transfer into Brain Capillary Endothelial Cells In Vivo with HVJ-liposomes (2002) (15)
Effect of 5-Fluorouracil on Gastrointestinal Carcinogenesis Induced by N-Methyl-N′-Nitro-N-Nitrosoguanidine in Rats (2004) (15)
Acute Induction of Adriamycin‐resistance in Human Colon Carcinoma HT‐29 Cells Exposed to a Sublethal Dose of Adriamycin (1995) (15)
Modulation of Multidrug Resistance by SDZ PSC 833 in Leukemic and Solid‐tumor‐bearing Mouse Models (1996) (15)
Circumvention of drug resistance with calcium channel blockers and monoclonal antibodies. (1989) (14)
Inhibitory effect of a spicamycin derivative, KRN5500, on the growth of hepatic metastasis of human colon cancer-producing tissue polypeptide antigen (1996) (14)
A Novel Multidrug Resistance in Cultured Leukemia and Lymphoma Cells Detected by a Monoclonal Antibody to 85‐kDa Protein, MRK20 (1989) (14)
Characterization of an Etoposide‐resistant Human K562 Cell Line, K/eto (1991) (14)
Caspase‐independent necrotic cell death induced by a radiosensitizer, 8‐nitrocaffeine (2004) (14)
Efficient Introduction of Macromolecules and Oligonucleotides into Brain Capillary Endothelial Cells Using HVJ-Liposomes (2000) (14)
Overcoming multi‐drug resistance using an intracellular anti‐MDR1 sFv (2001) (14)
Comparison of uptake of mitomycin C and KW-2149 by murine P388 leukemia cells sensitive or resistant to mitomycin C (2004) (14)
Chelating Compound, Chrysoidine, Is More Effective in Both Antiprion Activity and Brain Endothelial Permeability Than Quinacrine (2007) (14)
Elimination of drug-resistant myeloma tumor cell lines by monoclonal anti-P-glycoprotein antibody and rabbit complement. (1989) (14)
A Potent Telomerase Inhibitor Identified by Exploiting the Disease-oriented Screening Program with COMPARE Analysis 1 (1999) (14)
Elevated expression of P-glycoprotein in kidney and urinary bladder cancers. (1991) (14)
Development of Multidrug Resistance in Rodent Cell Lines (1991) (14)
Mechanism of multidrug resistance and implication for therapy (1994) (14)
Antitumor activity of 7-n-(p-hydroxyphenyl)-mitomycin C in experimental tumor systems. (1981) (13)
Multidrug Resistance Reversal Activity of Taxoids from Taxus cuspidate in KB‐C2 and 2780AD Cells (2000) (13)
Inhibition by Differentiation‐inducing Agents of Wild‐type p53‐dependent Apoptosis in HL‐60 Cells (1995) (13)
Protective action of indapamide, a thiazide-like diuretic, on ischemia-induced injury and barrier dysfunction in mouse brain microvascular endothelial cells. (2007) (13)
Expression of insulin receptor substrate-1 in hepatocytes: an investigation using monoclonal antibodies. (1994) (13)
Reversal of Multidrug Resistance by Novel Nitrophenyl Pyrones, SNF4435C and D (2001) (13)
Effects of inducers of erythroid differentiation of human leukemia K562 cells on vincristine-resistant K562/VCR cells. (1983) (13)
Molecular Cloning and Characterization of the Complementary DNA for the Mr 85,000 Protein Overexpressed in Adriamycin-resistant Human Tumor Cells (1993) (13)
Enhanced cytocidal action of methotrexate by conjugation to concanavalin A (1980) (13)
Two Taxoids from Taxus cuspidata as Modulators of Multidrag Resistant Tumor Cells (2001) (13)
SYNTHESIS AND ANTITUMOR ACTIVITY OF FUSED TETRACYCLIC QUINOLINE DERIVATIVES (1990) (13)
Synthesis and antitumor activity of tropolone derivatives. 2. (1985) (13)
A Novel Mutant from Apoptosis‐resistant Colon Cancer HT‐29 Cells Showing Hyper‐apoptotic Response to Hypoxia, Low Glucose and Cisplatin (1998) (12)
Kinetic analysis of the disposition of MRK16, an anti-P-glycoprotein monoclonal antibody, in tumors: comparison between in vitro and in vivo disposition. (1997) (12)
Antitumor effects of IST-622, a novel synthetic derivative of chartreusin, against murine and human tumor lines following oral administration (2004) (12)
Spontaneous metastasis of highly metastatic variants of mouse tumors and the effect of drugs on the metastasis. (1984) (12)
Inhibition of human immunodeficiency virus type 1 (HIV-1) replication by daphnodorins. (1994) (12)
Membrane affinity and metabolism of N4-palmitoyl-1-beta-D-arabinofuranosylcytosine into cultured KB cells. (1981) (12)
Inhibition of ubiquitin-ATP-dependent proteolysis and ubiquitination by cisplatin. (1991) (12)
Quantitative analysis of the cyclin expression in human esophageal cancer cell lines. (1998) (12)
Drug-selected complete restoration of superoxide generation in Epstein-Barr virus-transformed B cells from p47phox-deficient chronic granulomatous disease patients by using a bicistronic retrovirus vector encoding a human multi-drug resistance gene (MDR1) and the p47phox gene (1998) (12)
Prediction of risk of disease recurrence by genome-wide cDNA microarray analysis in patients with Philadelphia chromosome-positive acute lymphoblastic leukemia treated with imatinib-combined chemotherapy. (2007) (12)
Different susceptibilities of cultured mouse cell lines to mouse interferon. (1982) (12)
Mouse‐Human Chimeric Antibody MH171 against the Multidrug Transporter P‐Glycoprotein (1992) (12)
Evaluation of MS-209, a novel multidrug-resistance-reversing agent, in tumour-bearing mice by technetium-99m-MIBI imaging (2002) (12)
Retinoblastoma susceptibility protein, Rb, possesses multiple BRCT-Ws, BRCA1 carboxyl-terminus-related W regions with DNA break-binding activity (2000) (11)
Antitumor activity of a derivative of mitomycin, 7-N-[2-[[2-(γ-l-glutamylamino)ethyl]dithio]ethyl]mitomycin C (KW-2149), against murine and human tumors and a mitomycin C-resistant tumor in vitro and in vivo (2004) (11)
Synthesis and structure-activity relationships of taxuyunnanine C derivatives as multidrug resistance modulator in MDR cancer cells. (2007) (11)
Synthesis and antitumor activity of tropolone derivatives. 3. (1986) (11)
Increase in the Level of P‐Glycoprotein mRNA Expression in Multidrug‐resistant K562 Cell Lines Treated with Sodium Butyrate Is Not Accompanied with Erythroid Differentiation (1990) (11)
Relationship between multidrug resistant gene expression and multidrug resistant-reversing effect of MS-209 in various tumor cells (2004) (11)
Enhancement of Reversing Effect of Cyclosporin A on Vincristine Resistance by Anti‐P‐glycoprotein Monoclonal Antibody MRK‐16 (1993) (10)
Antitumor effects and pharmacology of orally administered N4-palmitoyl-1-beta-D-arabinofuranosylcytosine in mice. (1984) (10)
Three DNA polymerases of rat ascites hepatoma cells: properties of the enzymes and effect of RNA synthesis on the reactions. (1975) (10)
The polar neutral and basic taxoids isolated from needles and twigs of Taxus cuspidata and their biological activity (2008) (10)
Apoptosis inhibition by anti-M(r) 23,000 (Thy-1) monoclonal antibodies without inducing bcl-2 expression. (1995) (10)
Novel dithiane analogues of tiapamil with high activity to overcome multidrug resistance in vitro. (1995) (10)
Establishment and Characterization of Non‐small Cell Lung Cancer Cell Lines Resistant to Mitomycin C under Aerobic Conditions (1995) (10)
DRUG RESISTANCE PATHWAYS AS TARGETS (2002) (10)
Expression of multidrug resistance P-glycoprotein on peripheral blood mononuclear cells of patients with granular lymphocyte-proliferative disorders. (1993) (10)
Enhancement of vinblastine-induced cytotoxicity by lysolecithin and phosphatidylinositol. (1981) (10)
Adhesive properties of weakly and highly metastatic melanoma cell lines. (1984) (10)
Functional involvement of P-glycoprotein in blood-brain barrier. (1992) (10)
Resolution of 9-(c-4,t-5-bishydroxymethylcyclopent-2-en-r-1-yl)-9H-adenine and selective inhibition of human immunodeficiency virus by the (-) enantiomer. (1992) (10)
Requirement of expression of P-glycoprotein on human natural killer leukemia cells for cell-mediated cytotoxicity. (1998) (10)
Augmentation by Bispecific F(ab′)2 Reactive with P‐Glycoprotein and CD3 of Cytotoxicity of Human Effector Cells on P‐Glycoprotein Positive Human Renal Cancer Cells (1992) (9)
Antitumor activity of idarubicin, a derivative of daunorubicin, against drug sensitive and resistant P388 leukemia. (1993) (9)
Cysteine produced from lymph node stromal cells suppresses apoptosis of mouse malignant T-lymphoma cells. (1995) (9)
DNA polymerases of ascites hepatoma cells. I. Purification and properties of a DNA polymerase from soluble fraction. (1972) (9)
P-glycoprotein-mediated multidrug resistance and lymphokine-activated killer cell susceptibility in ovarian carcinoma (1996) (9)
Novel Antitumor Metabolites Produced by a Fungal Strain from a Sea Hare. (1998) (9)
Combined therapy with anti‐p‐glycoprotein antibody and macrophage colony‐stimulating factor gene transduction for multiorgan metastases of multidrug‐resistant human small cell lung cancer in nk cell‐depleted scid mice (1999) (9)
Correction: IL12RB2 and ABCA1 Genes Are Associated with Susceptibility to Radiation Dermatitis (2010) (9)
Enzyme catalyzation of the deacylation of N4-acyl derivatives of 1-beta-D-arabinofuranosylcytosine in the mouse liver microsome. (1982) (9)
Growth stimulating activity of lung extract on lung-colonizing colon 26 clones and its partial characterization (1988) (8)
In vivo imaging and specific targeting of P-glycoprotein expression in multidrug resistant nude mice xenografts with [125I]MRK-16 monoclonal antibody. (1995) (8)
Identification and Characterization of a Deletion Mutant of DNA Topoisomerase I mRNA in a Camptothecin‐resistant Subline of Human Colon Carcinoma (2000) (8)
Growth Inhibition of Multidrug-Resistant Cells by Monoclonal Antibodies against P-Glycoprotein (1991) (8)
Genetically recessive mutant of human monocytic leukemia U937 resistant to tumor necrosis factor‐α‐induced apoptosis (1998) (8)
Modulation of Adriamycin Resistance in Human Breast Carcinoma MCF‐7 Cells in vitro and in vivo by Medroxyprogesterone Acetate (1994) (8)
Expression of multidrug resistant gene (mdr-1/P-glycoprotein) in a megakaryoblastic cell line, CMK, and its enhancement during megakaryocytic differentiation. (1995) (8)
Evaluation of tankyrase inhibition in whole cells. (2007) (8)
Monoclonal antibodies to P-glycoprotein: preparation and applications to basic and clinical research. (1998) (8)
Therapeutic approach to drug resistant tumors. (1998) (8)
An endodeoxyribonuclease of human KB cells. Purification and properties of the enzyme. (1978) (8)
Potentiation of antitumor and antimetastatic activities of adriamycin by a novel N-alkylated dihydropyridine, AC394, and its enantiomers in colon cancer-bearing mice (1996) (8)
Human ovarian cancer cell lines resistant to cisplatin, doxorubicin, and l‐phenylalanine mustard are sensitive to Delta7‐prostaglandin A1 and Delta 12‐prostaglandin J2 (1992) (8)
In Vivo and In Vitro Toxicodynamic Analyses of New Quinolone-and Nonsteroidal Anti-Inflammatory Drug-Induced Effects on the Central Nervous System (1999) (8)
Induction of oncogene addiction shift to NF-kappaB by camptothecin in solid tumor cells. (2009) (8)
Low molecular weight DNA polymerase of rat ascites hepatoma cells. (1974) (7)
Delivery and cytotoxicity of RS-1541 in St-4 human gastric cancer cells in vitro by the low-density-lipoprotein pathway (2004) (7)
The synthesis and antitumor activities of tropolone and 8-hydroxyquinoline derivatives. (1986) (7)
Establishment and evaluation of MRK16-magnetic cell sorting assays for detecting low expression of multidrug resistance P-glycoprotein using human leukemia cell lines and peripheral blood cells from healthy donors. (1995) (7)
[Globalization of clinical trials]. (2003) (7)
Transduction of the Macrophage Colony‐stimulating Factor Gene into Human Multidrug Resistant Cancer Cells: Enhanced Therapeutic Efficacy of Monoclonal Anti‐P‐glycoprotein Antibody in Nude Mice (1996) (7)
Interleukin‐1α induces cyclooxygenase‐2 expression in bone‐derived endothelial cells (1999) (7)
Characterization of newly established adriamycin resistant human leukemic cell lines (KY-ADR1 and KY-ADR2). (1994) (7)
Application of in vivo ESR/spin-probe technique to monitor tumor in vivo in mouse footpad. (2007) (7)
p53 contains a DNA break-binding motif similar to the functional part of BRCT-related region of Rb (2001) (7)
Synthesis and antitumor activities of glycine-exchanged analogs of spicamycin. (1995) (7)
Functional interaction of DNA topoisomerase IIalpha with the beta-catenin and T-cell factor-4 complex. (2007) (7)
Synthesis of C-ring aromatic taxoids and evaluation of their multi-drug resistance reversing activity. (1998) (7)
A new taxoid from a callus culture of Taxus cuspidata as an MDR reversal agent. (2006) (7)
Isolation of a Novel Gene Showing Reduced Expression in Metastatic Colorectal Carcinoma Cell Lines and Carcinomas (1997) (7)
Anticancer activities of orally administered menogaril against human stomach and breast cancers implanted in nude mice. (1992) (7)
Cross-resistance of human multidrug-resistant cells to mitomycin C. (1991) (7)
Synthesis and evaluation of artificial taxoids with antitumor and multi-drug resistance reversing activities. (1998) (7)
PRMT 5 , a Novel TRAIL Receptor-Binding Protein , Inhibits TRAIL-Induced Apoptosis via Nuclear Factor-κ B Activation (2009) (7)
Synthesis and antitumor activity of tropolone derivatives. 5. (1987) (7)
Reconstitution of purified P-glycoprotein into liposomes (2005) (7)
Detection of multidrug-resistant protein, P-glycoprotein in childhood leukaemia and lymphoma (1991) (6)
Vincristine-resistant P388 leukemia cells contain a large amount of calcium. (1983) (6)
Interleukin-1 alpha induced cyclooxygenase-2 expression in bone-derived endothelial cells. (1999) (6)
Acquired vs innate multidrug resistance and the effect of calcium channel blockers. (1986) (6)
Transport of somatostatin and substance P by human P‐glycoprotein (2004) (6)
Isolation and characterization of a mitomycin C-resistant variant of human colon carcinoma HT-29 cells (2004) (6)
Integration of Proviral DNA in Chicken Cells Infected with Schmidt-Ruppin Rous Sarcoma Virus Is Not Enhanced by DNA Repair (1977) (6)
Screening with COMPARE analysis for telomerase inhibitors. (2002) (6)
Role of DNA-binding in the cytotoxicity of an anthracycline, R20X2 and its morpholino analog, MX2. (1989) (6)
Role of Heparin in Tumor Cell-Induced Platelet Aggregation (1986) (6)
Measurement of P-glycoprotein expression in multidrug-resistant human neuroblastoma cell lines using self-competitive binding assay. (1996) (6)
Multidrug Resistance (mdr1) in Adult Acute Leukemia at Diagnosis: Correlation with Response to Induction Chemotherapy (1993) (6)
Cyclosporin A Enhances Susceptibility of Multi‐drug Resistant Human Cancer Cells to Anti‐P‐glycoprotein Antibody‐dependent Cytotoxicity of Monocytes, but Not of Lymphocytes (1994) (6)
Research on the carbohydrate-peptide linkage of porcine pancreatic ribonuclease. (1970) (5)
Augmentation of 1-beta-D-arabinofuranosylcytosine resistance in human KB epidermoid carcinoma cells upon induction of a second resistance to vincristine. (1986) (5)
T cell receptor-extracellular constant regions as hetero-cross-linkers for immunoglobulin variable regions. (1993) (5)
Detection of 300-kilodalton membrane protein in adriamycin-resistant human tumor cells by a monoclonal antibody MRK18. (1990) (5)
Detection of P-glycoprotein in human urogenital carcinomas and its relationship to epidermal growth factor receptor expression. (1991) (5)
Tumorigenesis facilitated by Pten deficiency in the skin: evidence of p53-Pten complex formation on the initiation phase. (2005) (5)
[Platinum compounds in cancer therapy--past, present, and future]. (2001) (5)
Growth inhibition of Lewis lung carcinoma by an inorganic dye, Ruthenium Red. (1980) (5)
[Mechanism of multidrug resistant tumors and chemotherapeutic approaches against the resistant tumors]. (1997) (5)
A novel antitumor cyclic hexapeptide (RA-700) obtained from Rubiae radix. (1987) (5)
Expression of the 85-kd membrane protein in primary human breast cancer: relationship to hormone receptor levels, DNA ploidy, and tumor grade. (1995) (5)
Induction of resistance to 1-beta-D-arabinofuranosylcytosine in human H9 cell line by simian immunodeficiency virus. (1995) (5)
TGF-β Induces RANKL Expression in Vascular Endothelial Cells Derived from Bone * (2002) (4)
Induction of in vitro nuclear apoptosis activity coincides with the production of 50 kDa cytosolic protein (1997) (4)
Suppression of friend leukemia virus by bacillus calmette‐guérin and a streptococcal preparation, OK‐432 (1980) (4)
Differential expression of P-glycoprotein in cord blood and peripheral blood lymphocyte subpopulations. (1996) (4)
Establishment of human KB cells resistant to 1-beta-D-arabinofuranosylcytosine, and mechanisms of cellular resistance in isolated clones. (1984) (4)
Inhibition of murine colon adenocarcinomas and Lewis lung carcinoma by 1-hexylcarbamoyl-5-fluorouracil (2004) (4)
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Expression of 85‐kDa Protein of Adriamycin‐resistant Tumor Cells during Hematopoietic Differentiation of THP‐1 and HEL Cells (1992) (4)
Molecular cloning and characterization of the complementary DNA for the M(r) 85,000 protein overexpressed in adriamycin-resistant human tumor cells. (1993) (4)
Antitumor Activity of ME2303, a Fluorine‐containing Anthracycline, against Human Tumors Implanted in Nude Mice (1989) (4)
Analysis of Novel Metastasis‐associated Gene TI‐227 (2000) (4)
Establishment of a Hepatocyte Cell Line Producing Growth‐promoting Factors for Liver‐colonizing Tumor Cells (1996) (4)
Construction of MDR1 vectors for gene therapy. (1998) (4)
[Enhancement of cellular accumulation of cyclosporine by anti-P-glycoprotein monoclonal antibody MRK-16, and their synergistic modulation of multidrug resistance]. (1994) (3)
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High-level expression of P-glycoprotein and 85 kD protein as assessed by flow cytometry and immunocytochemistry in leukemias and malignant lymphomas. (1990) (3)
A new form of high molecular weight DNA polymerase in the nuclei of rat ascites hepatoma cells. (1975) (3)
Apoptosis resistance in tumor cells (1998) (3)
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Activity of tricyclic nucleoside 5′-phosphate in model systems of human ovarian cancer (2004) (3)
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Influence of systemic chemotherapy on anti-P-glycoprotein antibody-dependent cell-mediated cytotoxicity in patients with small cell lung cancer. (1995) (3)
Tolbutamide uptake via pH- and membrane-potential-dependent transport mechanism in mouse brain capillary endothelial cell line. (2004) (3)
Difference in effects of alkyl-lysophospholipids and verapamil on vincristine transport in vincristine-sensitive and -resistant human myelogenous leukemia K562. (1987) (3)
Measurement of P-glycoprotein expression in human neuroblastoma xenografts using in vitro quantitative autoradiography. (1999) (3)
Hypoxia-Adapted CML Cells Are More Primitive Population and Are Eradicated by Glyoxalase-1 Inhibitors. (2009) (3)
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Membrane Affinity and Metabolism of A/4-Palmitoyl-1-/?-D-Arabinofuranosylcytosine into Cultured KB Cells1 (2006) (2)
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Overcoming of multidrug resistance by VA-033, a novel derivative of apovincaminic acid ester. (1997) (2)
Antitumor efficacies of aclacinomycin A by oral administration. (1980) (2)
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A Polydeoxythymidylic acid-specific deoxyribonuclease from rat ascites hepatoma cells. (1975) (2)
Development of lymphosarcoma lines with high metastatic ability to lymph nodes and visceral organs in BALB/c mice (1988) (2)
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Multidrug resistance: a transport system of antitumor agents and xenobiotics. (1990) (2)
Intracellular activation and cytotoxic action of RS-1541 against cultured human tumor cells (1995) (2)
Enhanced metastasis of B16 melanoma cells by unexpected elevated expression of the metastasis-associatedTI-241 (LRF-1-, Jun-Fos-related) gene treated with antisense oligonucleotide (1998) (2)
Expression of the multidrug-resistant gene in human musculoskeletal tumors. (1992) (2)
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Synthesis and Antitumor Activity of Tropolone Derivatives. Part 7. Bistropolones Containing Connecting Methylene Chains. (1992) (2)
Purification and properties of a DNA ligase from a soluble DNA replication complex. (1980) (2)
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Enhancement of Adriamycin Cytotoxicity in Sensitive and Resistant Sublines of Human Tumor Cells by Calcium Antagonists (1990) (2)
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Establishment of highly metastatic variants of murine colon adenocarcinoma 26 under serum‐free conditions (1990) (1)
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MDR-related properties of K 562 cells grown in two different culture media. (1996) (1)
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PDK1-mediated IKKβ phosphorylation activates NF-κB signaling (2006) (1)
Purification and characterization of an amidohydrolase for N4-long-chain fatty acyl derivatives of 1-beta-D-arabinofuranosylcytosine from mouse liver microsomes. (1984) (1)
Histochemical Detection of Sugar Residues by Joint Use of Specific Antibodies and Lectins (1995) (1)
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ANTI-P-GLYCOPROTEIN FAB MRK-16 (1998) (0)
Caspase-3-like Death Protease is Inhibited by Interleukin-7 (1999) (0)
Re: Relationship between topotecan systemic exposure and tumor response in human neuroblastoma xenografts. (1998) (0)
Medicament anticancereux comprenant un derive d'acide anthranilique en tant qu'ingredient actif (2001) (0)
Smac Peptide : Therapeutic Effect of a Novel Polyarginine-conjugated CellsApoptosis Protein in Non-Small Cell Lung Cancer H 460 Predominant Suppression of Apoptosome by Inhibitor of Updated (2003) (0)
Editor's Statement (2007) (0)
Potentiation of adriamycin anti-tumor activity by MS-209 in murine colon 26 tumor: 79 (1994) (0)
Reply to Honoré: Masking of Signal Sequences in CREC Proteins by cDNA Subcloning in Epitope Vectors (2009) (0)
Erratum: Efficient introduction of macromolecules and oligonucleotides into brain capillary endothelial cells using HVJ-liposomes (Journal of Drug Targeting vol. 8 (4) (207-216)) (2001) (0)
Competitive Inhibitionby Verapamil of ATP-dependent HighAffinityVincristine Bindingto the PlasmaMembrane of Multidrug-resistant K562Cellswithout CalciumIonInvolvement1 (1989) (0)
Faculty Opinions recommendation of Selective compounds define Hsp90 as a major inhibitor of apoptosis in small-cell lung cancer. (2007) (0)
Retraction (2008) (0)
[Introduction to the symposium "Bio-informatics for Pharmaceutical Sciences and Pharmacy Education". Foreword]. (2008) (0)
Apoptosis Induced by Antitumor Agents (1998) (0)
Obituary (2009) (0)
Apoptosis of T lymphoma cells and its inhibition by monoclonal antibodies against cell surface adhesion molecules. (1994) (0)
Supplemental Data Binding and Phosphorylation of Par-4 by Akt Is Essential for Cancer Cell Survival (2005) (0)
Retraction for Motiwala et al., Protein tyrosine phosphatase receptor-type O (PTPRO) exhibits characteristics of a candidate tumor suppressor in human lung cancer (2022) (0)
Synthesis and Antitumor Activity of Tropolone Derivatives. Part 3. (1986) (0)
Synthesis and Antitumor Activity of Fused Tetracyclic Quinoline Derivatives. Part 1. (1989) (0)
TRANSPORT MECHANISM OF TOLBUTAMIDE ACROSS THE BLOOD-BRAIN BARRIER -Analysis of In Vivo-In Vitro Study- (1997) (0)
[Results of molecular screening of anti-cancer agents. 8. Results of screening of possible anti-cancer agents in Japan]. (2000) (0)
Quinoline Derivative , MS-073 Circumvention of Multidrug Resistance by a Newly Synthesized Updated Version (2006) (0)
[Implication of growth factors in tumor metastasis]. (1991) (0)
Detection of drug resistance in human hematologic malignancy by monoclonal antibodies. (1988) (0)
[Signal transduction of insulin-like growth factor I in a highly metastatic tumor cell line]. (1993) (0)
Potency of cremophor EL to reverse multidrug resistance: negligible reversing ability in P-glycoprotein-positive tumor bearing mice models (1994) (0)
[Pharmacogenomics: challenges in promoting its clinical usage]. (2008) (0)
Molecular Cloning and Characterization of the Complementary DNA for the Mr 85 , 000 Protein Overexpressed in Adriamycin-resistant Human Tumor Cells 1 (2006) (0)
AntitumorEffectsand Pharmacology of OrallyAdministered N4-Palmitoyl I -fi-D-arabinofuranosylcytosine in Mice1 (1984) (0)
Synthesis and Evaluation of Artificial Taxoids with Antitumor and Multi‐Drug Resistance Reversing Activities. (1999) (0)
[Molecule based diagnosis]. (2004) (0)
[Development of drugs to overcome drug resistance--basic approaches]. (1995) (0)
Comparisonof CytotoxicEffectand Cellular Uptakeof 1-fl-D- Arabinofuranosylcytosine and ItsN4-AcylDerivatives,Using CulturedKBCells' (1979) (0)
Quantitative estimation of tumor metastasis by measurement of DNA polymerse activity (2004) (0)
Galtonioside A, a Novel Cytotoxic Cholestane Glycoside from Galtonia candicans. (2000) (0)
[Antitumor drug screening at the National Cancer Institute, U.S.A]. (1987) (0)
[Cancer prevention]. (2005) (0)
[New approach in drug designing: molecular-targeted drugs]. (2002) (0)
[Therapeutic approaches for multidrug resistance]. (1988) (0)
[Tumor metastasis and growth factors]. (1989) (0)
Cellular FLIP Inhibits (cid:2) -Catenin Ubiquitylation and Enhances Wnt Signaling (2004) (0)
Retraction. Epigenetic regulator polycomb group protein complexes control cell fate and cancer, Cancer Science 2008; 99: 1077-84. (2008) (0)
System for the Board Certified Medical Oncologist in Japan (2005) (0)
platelet aggregation and suppresses pulmonary metastasis Tetraspanin family member CD9 inhibits Aggrus/podoplanin-induced (2008) (0)
Synthesis and Antitumor Activity of Tropolone Derivatives. Part 5. (1987) (0)
Topoisomerase IDNA Covalent Complex Cullin 3 Promotes Proteasomal Degradation of the Updated (2004) (0)
Scientific Proceedings Second International Symposium on Cytostatic Drug Resistance (1991) (0)
Molecular Cloning and Characterization of the Complementary DNA for the Mr 85,000 Protein Overexpressed in Adriamycin-resistant Human Tumor Cells1 (2006) (0)
[Results of random screening of antineoplastic agents in Japan. 5]. (1991) (0)
Expression Behavior of 85‐kDa Membrane Protein in Adriamycin‐resistant Tumor Cells and the Inhibition of Human Tumor Growth in Athymic Mice by MRK‐20 Monoclonal Antibody against the Protein (1993) (0)
Functional sialylated O -glycan to platelet aggregation on Aggrus (T1 a / podoplanin) molecules expressed in CHO cells (2004) (0)
Enhancement of reversing effect of PSC 833 and cyclosporin A on multidrug resistance by anti-P-glycoprotein monoclonal antibody MRK-16: 61 (1994) (0)
Cancer Molecular Therapeutics: Present status and genomic studies for their efficacy (2005) (0)
Reversal of drug resistance to antitumor agents by calcium antagonists (1983) (0)
[Chemotherapeutic approaches against drug resistant tumors]. (1996) (0)
DNA microarray analysis of tumors in versipelostatin (VST)-administered MKN74-xenograft nude mice (2007) (0)
Agent prophylactique/therapeutique pour le cancer (2007) (0)
Sensitivity of Xenografted Human Tumors to Antitumor Agents in vivo and in vitro (1989) (0)
P-glycoprotein expression in ovarian tumour biopsies taken before or after cytotoxic chemotherapy (1992) (0)
Synthesis and structure-activity relationships of antitumor-active tropolone derivatives (1989) (0)
In vivo drug-selectable markers in gene therapy. (1995) (0)
cancer Pancreas cancer Renal cancer Malignant lymphoma Gastric cancer Neuroblastoma Malignant fibrous histiocytoma Osteogenic sarcoma Lung cancer Ovarian cancer Uterine cervical cancer Smooth muscle sarcoma of the uterus Breast cancer Thymoma (2006) (0)
[Mechanism of resistance to antitumor agents--its involvement in blood-brain barrier]. (1995) (0)
Faculty Opinions recommendation of Interaction of KAI1 on tumor cells with DARC on vascular endothelium leads to metastasis suppression. (2006) (0)
Life Science and Its Border (2004) (0)
[ICE family proteins]. (1997) (0)
The Role of Interleukein-11 in the Formation of Bone Metastases (2001) (0)
[Early detection and prevention of cancers in various therapeutic areas. Discussion]. (1999) (0)
シンポジウム—バイオインフォーマティクスの薬学研究・薬学教育への応用と展開— (2008) (0)
[Tumor-induced platelet aggregation and growth-promoting factors as determinants of probable tumor metastasis]. (1987) (0)
[Translational research for cancer therapeutics]. (2003) (0)
Medicament for enhancing the therapeutic effect of anti-tumor agents and their use (1983) (0)
Immunohistochemical Detection of P-glycoprotein in malignant tumors of the head and neck (1992) (0)
Reviewer ' s report 3-Phosphoinositide-dependent Protein Kinase-1 ( PDK 1 ) Promotes Invasion and Activation of Title : Matrix Metalloproteinases 1 23 February 2006 Version : Date : Takashi Tsuruo (2006) (0)
[Detection of multidrug resistant cells in human malignant diseases by monoclonal antibodies and strategy to eradicate resistant malignant cells]. (1989) (0)
[Possible modality for overcoming drug resistance]. (1985) (0)
Faculty Opinions recommendation of Tumorigenic transformation by CPI-17 through inhibition of a merlin phosphatase. (2006) (0)
Taxuspines A ‐ C, New Taxoids from Japanese Yew Taxus cuspidata Inhibiting Drug Transport Activity of P‐Glycoprotein in Multidrug‐ Resistant Cells. (1994) (0)
[Therapeutic approach against drug-resistant tumors and their biochemical nature]. (1987) (0)
CompetitiveInhibitionby Verapamilof ATP-dependentHigh AffinityVincristine Bindingto the Plasma Membraneof Multidrug-resistantK562 Cells without CalciumIon Involvement1 (2006) (0)
Nucleic Acids Research Nucleic Acids Research (0)
SYNTHESIS AND ANTITUMOR ACTIVITY OF TROPOLONE DERIVATIVES. 2 (1985) (0)
Preliminary Crystallographic Analysis of Anti P-Glycoprotein Specific FAB MRK-16 in Complex with its Antigenic Peptide (1996) (0)
[Reversal of antitumor drug resistance by modification of membrane transport]. (1983) (0)
Heterocyclic compounds and drugs that enhance the action of anticancer agents containing them as effective ingredients. (1989) (0)
In Vivo and In Vitro Toxicodynamic Analyses of New Quinolone-and Nonsteroidal Anti-Inflammatory Drug-Induced Effects on the Central Nervous System (1999) (0)
[Therapeutic approach targeting the proteins involved in mechanisms of multidrug resistance]. (1988) (0)
[Overcoming of multidrug resistance and its clinical application]. (1997) (0)
Therapeutic Targets and Drugs III: Tankyrase 1, Telomere-Binding Proteins, and Inhibitors (2009) (0)
Twelve-gene expression profiling by quantitative RT-PCR as a novel predictive biomarker of gefitinib-treated non-small-cell lung cancer patients (2007) (0)
Specific imaging of hormone-dependent mammary carcinoma in nude mice with [131I]-anti-estriol 3-sulfate antibody. (1995) (0)
Incorporation of nucleotides into DNA by mammalian DNA polymerase in the presence of a single deoxynucleoside triphosphate. (1975) (0)
[Overcoming of multidrug resistance by a newly synthesized quinoline compound, MS-209]. (1997) (0)
Faculty Opinions recommendation of The role of SPINK1 in ETS rearrangement-negative prostate cancers. (2008) (0)
Glyoxalase-I Inhibition Eliminates Hypoxia-Adapted CML Cells Resistant to Imatinib, Dasatinib, and INNO-406 (2008) (0)

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