Takashi Yamamura
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Computer Science
Takashi Yamamura's Degrees
- PhD Computer Science University of Tokyo
- Masters Computer Science University of Tokyo
- Bachelors Computer Science University of Tokyo
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(Suggest an Edit or Addition)Takashi Yamamura's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- A synthetic glycolipid prevents autoimmune encephalomyelitis by inducing TH2 bias of natural killer T cells (2001) (887)
- Functionally Distinct Subsets of CD1d-restricted Natural Killer T Cells Revealed by CD1d Tetramer Staining (2002) (795)
- Siponimod versus placebo in secondary progressive multiple sclerosis (EXPAND): a double-blind, randomised, phase 3 study (2018) (559)
- Dysbiosis in the Gut Microbiota of Patients with Multiple Sclerosis, with a Striking Depletion of Species Belonging to Clostridia XIVa and IV Clusters (2015) (545)
- Thyrotrophin in the pars tuberalis triggers photoperiodic response (2008) (460)
- Light-induced hormone conversion of T4 to T3 regulates photoperiodic response of gonads in birds (2003) (450)
- Regulation of Experimental Autoimmune Encephalomyelitis by Natural Killer (NK) Cells (1997) (383)
- Interleukin 6 signaling promotes anti-aquaporin 4 autoantibody production from plasmablasts in neuromyelitis optica (2011) (344)
- Direct suppression of CNS autoimmune inflammation via the cannabinoid receptor CB1 on neurons and CB2 on autoreactive T cells (2007) (340)
- Modulation of CD1d-restricted NKT cell responses by using N-acyl variants of alpha-galactosylceramides. (2005) (320)
- Trial of Satralizumab in Neuromyelitis Optica Spectrum Disorder. (2019) (274)
- Efficacy of the anti–IL-6 receptor antibody tocilizumab in neuromyelitis optica (2014) (264)
- Cannabinoids and the immune system: Potential for the treatment of inflammatory diseases? (2005) (245)
- Differential Expression of NK T Cell Vα24JαQ Invariant TCR Chain in the Lesions of Multiple Sclerosis and Chronic Inflammatory Demyelinating Polyneuropathy1 (2000) (236)
- Th17 Cells and autoimmune encephalomyelitis (EAE/MS). (2008) (212)
- The clinical implication and molecular mechanism of preferential IL-4 production by modified glycolipid-stimulated NKT cells. (2004) (210)
- Cross-Regulation between Type I and Type II NKT Cells in Regulating Tumor Immunity: A New Immunoregulatory Axis1 (2007) (205)
- Natural killer T cells accelerate atherogenesis in mice. (2003) (200)
- NKT cell-dependent amelioration of a mouse model of multiple sclerosis by altering gut flora. (2008) (193)
- Interleukin 6 receptor blockade in patients with neuromyelitis optica nonresponsive to anti-CD20 therapy. (2013) (185)
- Seasonal morphological changes in the neuro-glial interaction between gonadotropin-releasing hormone nerve terminals and glial endfeet in Japanese quail. (2004) (175)
- Safety and efficacy of satralizumab monotherapy in neuromyelitis optica spectrum disorder: a randomised, double-blind, multicentre, placebo-controlled phase 3 trial (2020) (169)
- Th2 bias of CD4+ NKT cells derived from multiple sclerosis in remission. (2003) (169)
- Mucosal-associated invariant T cells regulate Th1 response in multiple sclerosis. (2011) (161)
- Influenza infection in suckling mice expands an NKT cell subset that protects against airway hyperreactivity. (2011) (157)
- Suppression of collagen-induced arthritis by natural killer T cell activation with OCH, a sphingosine-truncated analog of alpha-galactosylceramide. (2004) (156)
- A Structural Basis for the Association of DAP12 with Mouse, but Not Human, NKG2D1 (2004) (154)
- Cutting Edge: Human Th17 Cells Are Identified as Bearing CCR2+CCR5− Phenotype1 (2007) (152)
- Photoperiodic regulation of type 2 deiodinase gene in Djungarian hamster: possible homologies between avian and mammalian photoperiodic regulation of reproduction. (2004) (149)
- Circulating exosomes suppress the induction of regulatory T cells via let-7i in multiple sclerosis (2018) (147)
- Costimulation-Dependent Modulation of Experimental Autoimmune Encephalomyelitis by Ligand Stimulation of Vα14 NK T Cells1 (2001) (142)
- The regulatory role of natural killer cells in multiple sclerosis. (2004) (140)
- Relevance of Neuropeptide Y for the neuroimmune crosstalk (2003) (139)
- Monoclonal Antibodies Against Myelin Proteolipid Protein: Identification and Characterization of Two Major Determinants (1991) (135)
- Natural killer type 2 bias in remission of multiple sclerosis. (2001) (135)
- CD4+ NKT Cells, But Not Conventional CD4+ T Cells, Are Required to Generate Efferent CD8+ T Regulatory Cells Following Antigen Inoculation in an Immune-Privileged Site1 (2003) (132)
- Nogo-A and Nogo Receptor Expression in Demyelinating Lesions of Multiple Sclerosis (2005) (131)
- Microarray analysis identifies an aberrant expression of apoptosis and DNA damage-regulatory genes in multiple sclerosis (2005) (126)
- Circadian clock gene regulation of steroidogenic acute regulatory protein gene expression in preovulatory ovarian follicles. (2007) (123)
- Accumulation of Vα7.2–Jα33 invariant T cells in human autoimmune inflammatory lesions in the nervous system (2004) (123)
- Invariant NKT Cells Biased for IL-5 Production Act as Crucial Regulators of Inflammation1 (2007) (117)
- Mucosal-associated invariant T cells promote inflammation and exacerbate disease in murine models of arthritis. (2012) (116)
- Differential expression of NK T cell V alpha 24J alpha Q invariant TCR chain in the lesions of multiple sclerosis and chronic inflammatory demyelinating polyneuropathy. (2000) (114)
- T3 implantation mimics photoperiodically reduced encasement of nerve terminals by glial processes in the median eminence of Japanese quail (2006) (113)
- Invariant Vα19i T cells regulate autoimmune inflammation (2006) (112)
- Human astrocytes express aquaporin‐1 and aquaporin‐4 in vitro and in vivo (2007) (111)
- Clinical improvement in a patient with neuromyelitis optica following therapy with the anti-IL-6 receptor monoclonal antibody tocilizumab (2012) (111)
- Hypothalamic expression of thyroid hormone-activating and -inactivating enzyme genes in relation to photorefractoriness in birds and mammals. (2007) (106)
- NKT Cells Are Critical for the Initiation of an Inflammatory Bowel Response against Toxoplasma gondii1 (2005) (100)
- Cannabinoid-mediated neuroprotection, not immunosuppression, may be more relevant to multiple sclerosis (2008) (97)
- Long-day suppressed expression of type 2 deiodinase gene in the mediobasal hypothalamus of the Saanen goat, a short-day breeder: implication for seasonal window of thyroid hormone action on reproductive neuroendocrine axis. (2006) (96)
- Invariant V(alpha)19i T cells regulate autoimmune inflammation. (2006) (94)
- Murine CD160, Ig-Like Receptor on NK Cells and NKT Cells, Recognizes Classical and Nonclassical MHC Class I and Regulates NK Cell Activation1 (2005) (89)
- Synthetic glycolipid OCH prevents insulitis and diabetes in NOD mice. (2004) (89)
- Synthetic retinoid AM80 inhibits Th17 cells and ameliorates experimental autoimmune encephalomyelitis. (2009) (88)
- Eomesodermin-expressing T-helper cells are essential for chronic neuroinflammation (2015) (86)
- TROY and LINGO‐1 expression in astrocytes and macrophages/microglia in multiple sclerosis lesions (2007) (84)
- Microarray analysis identifies interferon β-regulated genes in multiple sclerosis (2003) (81)
- Suppression of Experimental Autoimmune Encephalomyelitis by Ghrelin1 (2009) (80)
- Experimental allergic encephalomyelitis induced by proteolipid apoprotein in Lewis rats (1986) (80)
- Stimulation of Host NKT Cells by Synthetic Glycolipid Regulates Acute Graft-versus-Host Disease by Inducing Th2 Polarization of Donor T Cells1 (2005) (79)
- Electrophysiological and Morphological Evidence for Synchronized GnRH Pulse Generator Activity Among Kisspeptin/Neurokinin B/Dynorphin A (KNDy) Neurons in Goats (2012) (79)
- The 14-3-3 protein epsilon isoform expressed in reactive astrocytes in demyelinating lesions of multiple sclerosis binds to vimentin and glial fibrillary acidic protein in cultured human astrocytes. (2004) (77)
- The involvement of V(alpha)14 natural killer T cells in the pathogenesis of arthritis in murine models. (2005) (77)
- Interleukin-6 in neuromyelitis optica spectrum disorder pathophysiology (2020) (77)
- Apathy/depression, but not subjective fatigue, is related with cognitive dysfunction in patients with multiple sclerosis (2014) (76)
- Alterations of the gut ecological and functional microenvironment in different stages of multiple sclerosis (2020) (75)
- Orphan nuclear receptor NR4A2 expressed in T cells from multiple sclerosis mediates production of inflammatory cytokines (2008) (74)
- Selective COX-2 inhibitor celecoxib prevents experimental autoimmune encephalomyelitis through COX-2-independent pathway. (2006) (74)
- Another View of T Cell Antigen Recognition: Cooperative Engagement of Glycolipid Antigens by Va14Ja18 Natural TCR 1 (2003) (74)
- Single Dose of OOCH Improves Mucosal T Helper Type 1/T Helper Type 2 Cytokine Balance and Prevents Experimental Colitis in the Presence of V&agr;14 Natural Killer T Cells in Mice (2005) (73)
- Gut environment-induced intraepithelial autoreactive CD4+ T cells suppress central nervous system autoimmunity via LAG-3 (2016) (72)
- The 14-3-3 Protein Forms a Molecular Complex with Heat Shock Protein Hsp60 and Cellular Prion Protein (2005) (71)
- Nuclear Receptor NR4A2 Orchestrates Th17 Cell-Mediated Autoimmune Inflammation via IL-21 Signalling (2013) (70)
- Accumulation of Valpha7.2-Jalpha33 invariant T cells in human autoimmune inflammatory lesions in the nervous system. (2004) (69)
- DM-20, a proteolipid apoprotein, is an encephalitogen of acute and relapsing autoimmune encephalomyelitis in mice. (1986) (67)
- Preferential T(h)2 polarization by OCH is supported by incompetent NKT cell induction of CD40L and following production of inflammatory cytokines by bystander cells in vivo. (2005) (66)
- Neuropeptide Y (NPY) Suppresses Experimental Autoimmune Encephalomyelitis: NPY1 Receptor-Specific Inhibition of Autoreactive Th1 Responses In Vivo 1 (2003) (66)
- Microarray analysis identifies a set of CXCR3 and CCR2 ligand chemokines as early IFNβ-responsive genes in peripheral blood lymphocytes in vitro: an implication for IFNβ-related adverse effects in multiple sclerosis (2006) (65)
- Regulation of NKT Cells by Ly49: Analysis of Primary NKT Cells and Generation of NKT Cell Line1 (2001) (65)
- CCR2+CCR5+ T Cells Produce Matrix Metalloproteinase-9 and Osteopontin in the Pathogenesis of Multiple Sclerosis (2012) (63)
- Understanding the behavior of invariant NKT cells in autoimmune diseases (2007) (61)
- T cell gene expression profiling identifies distinct subgroups of Japanese multiple sclerosis patients (2006) (60)
- Kisspeptin as a master player in the central control of reproduction in mammals: an overview of kisspeptin research in domestic animals. (2013) (59)
- IFN-γ-mediated negative feedback regulation of NKT cell function by CD94/NKG2 (2005) (58)
- Plasmablasts as Migratory IgG-Producing Cells in the Pathogenesis of Neuromyelitis Optica (2013) (57)
- More sympathy for autoimmunity with neuropeptide Y? (2004) (56)
- Sex steroid‐induced neuroplasticity and behavioral activation in birds (2010) (54)
- Molecular network of the comprehensive multiple sclerosis brain-lesion proteome (2009) (53)
- Rapid identification of 14-3-3-binding proteins by protein microarray analysis (2006) (52)
- Differential effects of fingolimod on B-cell populations in multiple sclerosis (2014) (51)
- Another view of T cell antigen recognition: cooperative engagement of glycolipid antigens by Va14Ja18 natural T(iNKT) cell receptor [corrected]. (2003) (48)
- Gene Expression Profile Following Stable Expression of the Cellular Prion Protein (2004) (46)
- Molecular Network Analysis of T-Cell Transcriptome Suggests Aberrant Regulation of Gene Expression by NF-κB As a Biomarker for Relapse of Multiple Sclerosis (2008) (46)
- Therapeutic potential of glycolipid ligands for natural killer (NK) T cells in the suppression of autoimmune diseases. (2005) (45)
- Analysis of proteolipid protein (PLP)-specific T cells in multiple sclerosis: identification of PLP 95-116 as an HLA-DR2,w15-associated determinant. (1995) (45)
- Gut microbiota-dependent CCR9+CD4+ T cells are altered in secondary progressive multiple sclerosis (2019) (45)
- Hla-DR2-restricted responses to proteolipid protein 95-116 peptide cause autoimmune encephalitis in transgenic mice. (2000) (44)
- Abnormalities of cerebral blood flow in multiple sclerosis: a pseudocontinuous arterial spin labeling MRI study. (2013) (44)
- Differential Expression of CD11c by Peripheral Blood NK Cells Reflects Temporal Activity of Multiple Sclerosis1 (2006) (44)
- Intradermal NKT cell activation during DNA priming in heterologous prime‐boost vaccination enhances T cell responses and protection against Leishmania (2008) (41)
- Androgens and Estrogens Synergistically Regulate the Expression of Doublecortin and Enhance Neuronal Recruitment in the Song System of Adult Female Canaries (2011) (40)
- Heterogeneity and continuum of multiple sclerosis phenotypes in Japanese according to the results of the fourth nationwide survey (2009) (39)
- Total synthesis of an immunosuppressive glycolipid, (2S,3S,4R)-1-O- (alpha-d-galactosyl)-2- tetracosanoylamino-1,3,4-nonanetriol. (2005) (38)
- Heterogeneous induction of 72-kDa heat shock protein (HSP72) in cultured mouse oligodendrocytes and astrocytes (1992) (37)
- NKT cells and autoimmune diseases: unraveling the complexity. (2007) (37)
- Effects of intravenous administration of neurokinin receptor subtype-selective agonists on gonadotropin-releasing hormone pulse generator activity and luteinizing hormone secretion in goats (2014) (35)
- A Population of Kisspeptin/Neurokinin B Neurons in the Arcuate Nucleus May Be the Central Target of the Male Effect Phenomenon in Goats (2013) (34)
- The Complementarity Determining Region 2 of BV8S2 (Vβ8.2) Contributes to Antigen Recognition by Rat Invariant NKT Cell TCR1 (2006) (33)
- MicroRNA-101a regulates microglial morphology and inflammation (2017) (33)
- NKT cell-stimulating synthetic glycolipids as potential therapeutics for autoimmune disease. (2004) (33)
- Activation of invariant natural killer T cells by synthetic glycolipid ligands suppresses autoantibody-induced arthritis. (2007) (33)
- IFN-gamma-mediated negative feedback regulation of NKT-cell function by CD94/NKG2. (2005) (33)
- Heterozygous null mutation of myelin P0 protein enhances susceptibility to autoimmune neuritis targeting P0 peptide (2003) (29)
- Identification of autoimmune T-cells among in vivo expanded CD25+ T-cells in multiple sclerosis (1998) (29)
- Minimum structure requirement of immunomodulatory glycolipids for predominant Th2 cytokine induction and the discovery of non-linear phytosphingosine analogs. (2007) (29)
- Resilience and depression/anxiety symptoms in multiple sclerosis and neuromyelitis optica spectrum disorder. (2018) (29)
- Human astrocytes express 14-3-3 sigma in response to oxidative and DNA-damaging stresses (2006) (28)
- Role of NK cells and invariant NKT cells in multiple sclerosis. (2010) (27)
- Neuromyelitis optica/Devic's disease: Gene expression profiling of brain lesions (2008) (26)
- Aberrant transcriptional regulatory network in T cells of multiple sclerosis (2007) (25)
- New cyclooxygenase‐2 inhibitors for treatment of experimental autoimmune neuritis (2002) (25)
- Tissue culture methods to study neurological disorders: Establishment of immortalized Schwann cells from murine disease models (2003) (25)
- Gut environmental factors and multiple sclerosis (2019) (25)
- Disrupted balance of T cells under natalizumab treatment in multiple sclerosis (2016) (24)
- Red jungle fowl (Gallus gallus) as a model for studying the molecular mechanism of seasonal reproduction. (2009) (24)
- Foveal thinning in neuromyelitis optica (2017) (24)
- GRAIL (Gene Related to Anergy in Lymphocytes) Regulates Cytoskeletal Reorganization through Ubiquitination and Degradation of Arp2/3 Subunit 5 and Coronin 1A* (2011) (23)
- Involvement of cytotoxic Eomes-expressing CD4+ T cells in secondary progressive multiple sclerosis (2021) (22)
- Autonomic regulation of experimental autoimmune encephalomyelitis in IL-4 knockout mice (1999) (20)
- TCR repertoire to proteolipid protein (PLP) in multiple sclerosis (MS): homologies between PLP-specific T cells and MS-associated T cells in TCR junctional sequences. (1996) (20)
- Development of novel neurokinin 3 receptor (NK3R) selective agonists with resistance to proteolytic degradation. (2014) (20)
- A concise synthesis of (3S,4S,5R)-1-(α-d-galactopyranosyl)-3-tetracosanoylamino-4,5-decanediol, a C-glycoside analogue of immunomodulating α-galactosylceramide OCH (2005) (20)
- Molecular Mechanism of Photoperiodic Time Measurement in the Brain of Japanese Quail (2006) (20)
- Development of a culture system to induce microglia-like cells from haematopoietic cells (2013) (20)
- Sodium butyrate, a histone deacetylase inhibitor, regulates Lymphangiogenic factors in oral cancer cell line HSC-3. (2014) (20)
- HSP72 induction by heat stress is not universal in mammalian neural cell lines (1994) (19)
- Altered Structural Brain Networks Related to Adrenergic/Muscarinic Receptor Autoantibodies in Chronic Fatigue Syndrome (2020) (19)
- Extrapituitary prolactin promotes generation of Eomes-positive helper T cells mediating neuroinflammation (2019) (19)
- Brain abnormalities in myalgic encephalomyelitis/chronic fatigue syndrome: Evaluation by diffusional kurtosis imaging and neurite orientation dispersion and density imaging (2018) (18)
- Retinoid signals and Th17-mediated pathology. (2009) (18)
- Analysis of T cell antigen receptors of myelin basic protein specific T cells in SJL/J mice demonstrates an alpha chain CDR3 motif associated with encephalitogenic T cells. (1994) (18)
- Review: Treatment of neuromyelitis optica: Current debate (2008) (18)
- The Effects of Chronic Subcutaneous Administration of an Investigational Kisspeptin Analog, TAK-683, on Gonadotropin-Releasing Hormone Pulse Generator Activity in Goats (2014) (18)
- Epiregulin is critical for the acinar cell regeneration of the submandibular gland in a mouse duct ligation model. (2014) (18)
- A 4-trifluoromethyl analogue of celecoxib inhibits arthritis by suppressing innate immune cell activation (2012) (17)
- Subcortical vascular encephalopathy in a normotensive, young adult with premature baldness and spondylitis deformans A clinicopathological study and review of the literature (1987) (17)
- A neurokinin 3 receptor-selective agonist accelerates pulsatile luteinizing hormone secretion in lactating cattle† (2017) (17)
- Demonstration of interleukin‐3 receptor‐associated antigen in the central nervous system (1995) (17)
- Passive transfer of experimental allergic encephalomyelitis induced by proteolipid apoprotein (1986) (17)
- Orientation of the myelin proteolipid protein C‐terminus in oligodendroglial membranes (1992) (16)
- Efficacy, safety, and pharmacokinetics of natalizumab in Japanese multiple sclerosis patients: A double-blind, randomized controlled trial and open-label pharmacokinetic study. (2017) (16)
- Involvement of transforming growth factor alpha in the photoperiodic regulation of reproduction in birds. (2007) (16)
- Mapping of KNDy neurons and immunohistochemical analysis of the interaction between KNDy and substance P neural systems in goat (2017) (16)
- New-onset type 1 diabetes mellitus and anti-aquaporin-4 antibody positive optic neuritis associated with type 1 interferon therapy for chronic hepatitis C. (2012) (15)
- Psychological Stress Increases Human T Cell Apoptosis in vitro (2003) (15)
- Another View of T Cell Antigen Recognition: Cooperative Engagement of Glycolipid Antigens by Va14Ja18 Natural TCR (2004) (14)
- The Role for Exosomal microRNAs in Disruption of Regulatory T Cell Homeostasis in Multiple Sclerosis (2018) (14)
- A Trifluoromethyl Analogue of Celecoxib Exerts Beneficial Effects in Neuroinflammation (2013) (13)
- A novel compound heterozygous mutation in the DAP12 gene in a patient with Nasu-Hakola disease (2007) (13)
- A randomized placebo-controlled trial of delayed-release dimethyl fumarate in patients with relapsing-remitting multiple sclerosis from East Asia and other countries (2019) (13)
- Detection of anti‐Nogo receptor autoantibody in the serum of multiple sclerosis and controls (2007) (13)
- Suppression of experimental allergic encephalomyelitis by 15-deoxyspergualin (1987) (13)
- T-T cellular interaction between CD4-CD8- regulatory T cells and T cell clones presenting TCR peptide. Its implication for TCR vaccination against experimental autoimmune encephalomyelitis. (1996) (13)
- Peripheral clock gene expression in CS mice with bimodal locomotor rhythms (2006) (12)
- Peripheral administration of κ-opioid receptor antagonist stimulates gonadotropin-releasing hormone pulse generator activity in ovariectomized, estrogen-treated female goats. (2019) (12)
- Diet, Gut Flora, and Multiple Sclerosis: Current Research and Future Perspectives (2013) (12)
- Skewing of the B cell receptor repertoire in myalgic encephalomyelitis/chronic fatigue syndrome (2021) (12)
- Synthetic glycolipid ligands for human iNKT cells as potential therapeutic agents for immunotherapy. (2008) (12)
- Carcinoembryonic antigen-related cell adhesion molecule 1 modulates experimental autoimmune encephalomyelitis via an iNKT cell-dependent mechanism. (2009) (11)
- Efficacy of satralizumab (SA237) in subgroups of patients in SAkuraSky: a Phase III double-blind, placebo-controlled, add-on study in patients with neuromyelitis optica spectrum disorder (NMOSD) (S43.008) (2019) (11)
- Extracellular Vesicles as Pro- and Anti-inflammatory Mediators, Biomarkers and Potential Therapeutic Agents in Multiple Sclerosis (2021) (10)
- Plasma IP-10 level distinguishes inflammatory myopathy (2015) (10)
- Multiple sclerosis: Possibility of a gut environment-induced disease (2019) (10)
- Tocilizumab, MS, and NMOSD (2016) (10)
- Prophylactic and Therapeutic Effect of Bactobolin on Autoimmune Encephalomyelitis (1987) (9)
- Coexistence of cholinergic, catecholaminergic, serotonergic, and glutamatergic neurotransmitter markers in mouse clonal hybrid neurons derived from the septal region (1992) (9)
- Therapeutic Potential of CD1d-Restricted Invariant Natural Killer T Cell–based Treatment for Autoimmune Diseases (2007) (9)
- Localization of NK1.1(+) invariant Valpha19 TCR(+) cells in the liver with potential to promptly respond to TCR stimulation. (2008) (9)
- Ghrelin: friend or foe for neuroinflammation. (2009) (9)
- Association of cognitive impairment with magnetic resonance imaging findings and social activities in patients with multiple sclerosis (2014) (9)
- Multiple Sclerosis Immunology (2013) (9)
- T lymphocyte lines and clones selected against synthetic myelin basic protein 82–102 peptide from Japanese multiple sclerosis patients (1993) (9)
- Normal brain imaging accompanies neuroimmunologically justified, autoimmune encephalomyelitis (2018) (9)
- Synthesis and biological evaluation of truncated α-galactosylceramide derivatives focusing on cytokine induction profile. (2012) (8)
- B-cell-directed therapy: which B cells should be targeted and how? (2012) (8)
- Gut microbiome research in multiple sclerosis (2021) (8)
- ACCURATE LOCALIZATION OF INSULINOMA USING PERCUTANEOUS TRANSHEPATIC PORTAL VENOUS SAMPLING—USEFULNESS OF SIMULTANEOUS MEASUREMENT OF PLASMA INSULIN AND GLUCAGON LEVELS (1985) (8)
- Increase of Ki-67+ natural killer cells in multiple sclerosis patients treated with interferon-β and interferon-β combined with low-dose oral steroids (2011) (8)
- Neuromyelitis optica spectrum disorders: Emerging therapies (2017) (8)
- Suppression of Experimental Autoimmune Encephalomyelitis by Ghrelin (2009) (7)
- Neuromyelitis optica spectrum disorder and multiple sclerosis: Differentiation by a multimodal approach. (2015) (7)
- Efficacy of tocilizumab for fulminant multiple sclerosis with a tumefactive cervical lesion: A 12-year-old boy. (2019) (7)
- Characterization of expanded T cell clones in healthy macaques: ontogeny, distribution and stability. (2000) (6)
- Pigmented oral carcinoma in situ: a case report and literature review. (2014) (6)
- A double-blind placebo-controlled study of satralizumab (SA237), a recycling anti-IL-6 receptor monoclonal antibody, as add-on therapy for neuromyelitis optica spectrum disorder (NMOSD) (2018) (6)
- Long-term safety of satralizumab in neuromyelitis optica spectrum disorder (NMOSD) from SAkuraSky and SAkuraStar. (2022) (6)
- An assessment of mast cells and myofibroblasts in denture-induced fibrous hyperplasia. (2014) (6)
- A structural MRI study of cholinergic pathways and cognition in multiple sclerosis (2017) (6)
- [Neurologic Abnormalities in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Review]. (2018) (6)
- Safety and Efficacy of Natalizumab in Japanese Patients with Relapsing-Remitting Multiple Sclerosis: Open-Label Extension Study of a Phase 2 Trial (2016) (5)
- Patient-reported burden of symptoms in neuromyelitis optica: A secondary analysis on pain and quality of life (2021) (5)
- Establishment of mouse-immortalized hybrid clones expressing characteristics of differentiated neurons derived from the cerebellar and brain stem regions. (1992) (5)
- Interleukin 17-producing T-helper cells and autoimmune diseases: Time for a paradigm shift? (2007) (4)
- Structure–activity relationship study on senktide for development of novel potent neurokinin-3 receptor selective agonists (2015) (4)
- Autoimmune regulator gene, Aire, is involved in central tolerance to the DM20 isoform of proteolipid protein and the prevention of autoimmune inflammation (2014) (4)
- [Use of tocilizumab, an antibody against interleukin-6 receptor, for the treatment of neuromyelitis optica]. (2014) (4)
- Recovery mechanisms from experimental allergic encephalomyelitis in rats: analyses by using encephalitogenic T cell line. (1987) (4)
- Potential of targeting natural killer T cells for the treatment of autoimmune diseases (2004) (4)
- Potential benefits of the anti-IL-6 receptor antibody tocilizumab in multiple sclerosis patients with high plasmablast frequency (2017) (4)
- Back to the future for multiple sclerosis therapy: focus on current and emerging disease-modifying therapeutic strategies. (2009) (4)
- [Infection and multiple sclerosis]. (1999) (4)
- A double-blind placebo-controlled study of satralizumab (SA237), a recycling anti-IL-6 receptor monoclonal antibody, as add-on therapy for neuromyelitis optica (NMO) and NMO spectrum disorder (NMOSD) (2018) (3)
- Local administration of Neurokinin B in the arcuate nucleus accelerates the neural activity of the GnRH pulse generator in goats (2021) (3)
- [Therapeutic strategy for multiple sclerosis targeting NK and NKT cells]. (2001) (3)
- Th1 ‐ CD11c + B Cell Axis Associated with Response to Plasmapheresis in Multiple Sclerosis (2021) (3)
- Intravaginal administration of progesterone using a new technique for sustained drug release in goats (2020) (3)
- Efficacy of satralizumab in subgroups of patients in SAkuraSky: A phase III double-blind, placebo-controlled, add-on study in patients with neuromyelitis optica spectrum disorder (NMOSD) (2019) (3)
- Exploring steroid tapering in patients with neuromyelitis optica spectrum disorder treated with satralizumab in SAkuraSky: A case series. (2022) (3)
- Application of immunotherapy for neurological manifestations in hypermobile Ehlers–Danlos syndrome (2018) (3)
- Intrathymic Plasmablasts Are Affected in Patients With Myasthenia Gravis With Active Disease (2021) (3)
- Gut microbiome dysbiosis shapes disease course in the different stages of multiple sclerosis (2021) (3)
- Cell Activation Nonclassical MHC Class I and Regulates NK and NKT Cells , Recognizes Classical and Murine CD 160 , Ig-Like Receptor on NK Cells (2005) (3)
- [Nephrotic syndrome in multiple sclerosis patients who had undergone long-term interferon β-1b therapy]. (2013) (3)
- Once‐daily glatiramer acetate decreases magnetic resonance imaging disease activity in Japanese patients with relapsing–remitting multiple sclerosis (2017) (3)
- Efficacy of Satralizumab (SA237) As Add-on Therapy in Pre-Specified Additional Analyses of Sakurasky, a Double-Blind Placebo-Controlled Phase 3 Study in Patients with Neuromyelitis Optica Spectrum Disorders (NMOSD) (2019) (2)
- MicroRNA-101a regulates microglial morphology and inflammation (2017) (2)
- Recognition by Rat Invariant NKT Cell TCR 8 . 2 ) Contributes to Antigen β of BV 8 S 2 ( V The Complementarity Determining Region 2 Kronenberg and (2006) (2)
- [Pathogenesis of chronic inflammatory demyelinating polyneuropathy]. (2013) (2)
- [Involvement of NK and NKT cells in the pathogenesis of multiple sclerosis]. (2003) (2)
- An α‐chain TCR CDR3 peptide can enhance EAE induced by myelin basic protein or proteolipid protein (1996) (2)
- Efficacy and Safety of Satralizumab for Relapse Prevention in Neuromyelitis Optica Spectrum Disorder: A Pooled Analysis from Two Phase 3 Clinical Trials (2020) (2)
- Long-term Efficacy of Satralizumab in AQP4-IgG–Seropositive Neuromyelitis Optica Spectrum Disorder From SAkuraSky and SAkuraStar (2022) (2)
- Cellular Immunity and Multiple Sclerosis: Current Understanding (2016) (2)
- Natalizumab for Achieving Relapse-Free, T1 Gadolinium-Enhancing-Lesion-Free, and T2 Lesion-Free Status in Japanese Multiple Sclerosis Patients: A Phase 2 Trial Subanalysis (2017) (2)
- T Regulatory Cells Following Antigen + Cells , Are Required to Generate Efferent CD 8 T + NKT Cells , But Not Conventional CD 4 + CD (2003) (2)
- Inoculation in an Immune-Privileged Site T Regulatory Cells Following Antigen + Cells , Are Required to Generate Efferent CD 8 T + NKT Cells , But Not Conventional CD 4 + CD 4 (2003) (2)
- OR.27. CCR2 As a Marker for Human T-Cells Producing IL-17 (2006) (1)
- OCH, a newly synthetic glycolipid, enhances protective immunity against mouse DSS-induced colitis in the presence of Vα14 natural killer T cells (2003) (1)
- Multiple sclerosis (PP-038) (2010) (1)
- Plasmablasts and neuroimmunological disorders (2019) (1)
- Testosterone increases cell turnover in song nucleus HVC and increases cell recruitment into Area X of adult female canaries. (2010) (1)
- Heat-inducible expression of 72-kilodalton heat shock protein (HSP72) on cultured mouse oligodendrocytes and astrocytes (1991) (1)
- [Treatment of multiple sclerosis: current opinion]. (2001) (1)
- Versatile Orphan Nuclear Receptor NR4A2 as a Promising Molecular Target for Multiple Sclerosis and Other Autoimmune Diseases (2012) (1)
- Abrogation of spleen macrophage suppressive activity by 15-deoxyspergualin. (1989) (1)
- Efficacy and safety of satralizumab from two phase 3 trials in neuromyelitis optica spectrum disorder (2020) (1)
- Immuno-pathogenesis of neuromyelitis optica and emerging therapies (2022) (1)
- Activation of effector cells of experimental allergic encephalomyelitis in Lewis rats: comparison of T-cell lines with primary cultured lymph node cells. (1986) (1)
- [Molecular target drug development for curing multiple sclerosis]. (2009) (1)
- [Plasmablast in the pathology of multiple sclerosis]. (2015) (1)
- Silkworm recombinant bovine zona pellucida protein 4 (bZP4) as a potential female immunocontraceptive antigen; impaired sperm-oocyte interaction and ovarian dysfunction (2021) (1)
- Immune-mediated neurodegenerative trait provoked by multimodal derepression of long-interspersed nuclear element-1 (2022) (1)
- [Identification of a possible therapeutic target through pathogenic T cell analysis of multiple sclerosis]. (2009) (1)
- Dysregulation of T and B cells in myalgic encephalomyelitis/chronic fatigue syndrome (2017) (1)
- [Multiple sclerosis and regulatory cells]. (2005) (1)
- Functional Involvement of NR4A2 in the Pathogenesis of Multiple Sclerosis (2007) (1)
- [Synthetic glycolipid ligands as novel therapeutics for multiple sclerosis]. (2005) (1)
- OR.87. Aire-deficient Mice Develop Spontaneous Autoimmunity to the Central Nervous System Antigens (2009) (0)
- OR.15. New Synthetic Glycolipid Ligands for NKT Cells Suppresses Antibody-Induced Arthritis (2006) (0)
- Contents, Vol. 79, 1986 (1986) (0)
- [Antibody treatment for multiple sclerosis and neuromyeitis optica]. (2011) (0)
- Neuropilin‐1 (NRP1) – a new marker for pathogenic autoreactive T helper cells in autoimmune disease (2023) (0)
- Expression of the orphan nuclear receptor NR4A2 is required for IL-17 production by Th17 cells and the induction of Th17-mediated autoimmunity (93.14) (2010) (0)
- Multiple sclerosis (WS-038) Chairpersons: Jyun-ichi Kira, Richard Ransohoff (2010) (0)
- Corrigendum (2016) (0)
- [Regulatory T cell network]. (1994) (0)
- Differential roles of NK and NK-T cells for regulation of EAE (1998) (0)
- How do T cells mediate central nervous system inflammation? (2014) (0)
- Neuroimmunology (WS-012) Chairpersons: Takashi Yamamura, Britta Engelhardt (2010) (0)
- Ratio of lymphocyte to monocyte area under the curve as a novel predictive factor for severe infection in multiple sclerosis (2023) (0)
- NR4A2 controls pathogenic “switched” Th17 cells in the CNS during autoimmune inflammation (2014) (0)
- Neuroimmunology (PP-012) (2010) (0)
- [TCR peptide vaccination for autoimmune diseases: involvement of T-T interaction between autoimmune T cells presenting TCR peptide and CD4-CD8- regulatory T cells]. (1997) (0)
- CCR9+ CD4+ Memory t cells dependent on gut microbiota and age are altered in secondary progressive multiple sclerosis (2017) (0)
- The synthetic glycolipid OCH, a stimulant of NKT cells, inhibits Th1 cell–mediated ocular inflammation, but enhances disease induced by Th2 cells. (2004) (0)
- Encephalomyelitis by Ghrelin Suppression of Experimental Autoimmune (0)
- Type II NKT cells suppress tumor immunosurveillance enhanced by type I NKT cells (50.16) (2007) (0)
- NKG2D DAP12 with Mouse, but Not Human, A Structural Basis for the Association of (0)
- New Immunoregulatory Axis A NKT Cells in Regulating Tumor Immunity: Cross-Regulation between Type I and Type II (2013) (0)
- Long‐term, single‐arm, open‐label, multicenter phase 2/4 study of glatiramer acetate by subcutaneous injection in Japanese patients with relapsing–remitting multiple sclerosis (2018) (0)
- Pathogenic Microglia Orchestrate Neurotoxic Properties of Eomes-Expressing Helper T Cells (2023) (0)
- [Animal models for multiple sclerosis]. (2015) (0)
- Primary NKT Cells and Generation of NKT Regulation of NKT Cells by Ly49: Analysis of (2001) (0)
- Suppression of EAE by double-negative (CD4−CD8−) T cells responding to syngeneic encephalitogenic T cell clones (1991) (0)
- [Experimental autoimmune encephalomyelitis: crosstalk with immunology and therapy]. (2014) (0)
- Clinical course of multiple sclerosis in Japanese patients treated with glatiramer acetate (2017) (0)
- [The pathogenic mechanism of experimental autoimmune encephalomyelitis and approach for new immunological therapy]. (1994) (0)
- Review article Cannabinoids and the immune system: Potential for the treatment of inflammatory diseases? (2005) (0)
- Gut intraepithelial myelin reactive CD4+T cells suppress central nervous system autoimmunity via LAG3 (2016) (0)
- Chemokine receptor expressions on T cells in chronic inflammatory demyelinating polyneuropathy (2014) (0)
- [Molecular targeted therapy]. (2014) (0)
- Study of eomesodermin‐expressing CD4+ T cells sheds new light on the pathogenesis of secondary progressive multiple sclerosis (2016) (0)
- First-in-human clinical trial of the NKT cell-stimulatory glycolipid OCH in multiple sclerosis (2023) (0)
- An immunomodulatory role of a B-crystallin in mutiple sclerosis (2010) (0)
- Proteolipid 95–116-specific T cell response in DR2 transgenic mice (1998) (0)
- FELINE IMMUNODEFICIENCY VIRUS-ASSOCIATED NEURO-PATHOLOGICAL ALTERATIONS INDUCED BY INFLAMMATORY CYTOKINES (1999) (0)
- Extrathymic induction of T cells specific for myelin autoantigens (1994) (0)
- T cells are altered in secondary progressive multiple sclerosis (2019) (0)
- The immuno-regulatory role of natural killer T cells in inflammatory disease/ editor J.L. Croxford ; chief editorial consultant T. Yamamura (2005) (0)
- Ribonucleic acid sequencing data mining: A new tool for understanding neuroimmunological conditions (2016) (0)
- Inflammation Production Act as Crucial Regulators of Invariant NKT Cells Biased for IL-5 Porcelli , (2007) (0)
- NPY ameliorates experimental autoimmune encephalitis (EAE): Y1 receptor specific induction of a Th2 shift in vivo * (2003) (0)
- [New strategies for treatment of multiple sclerosis based on the autoimmune pathogenesis]. (1994) (0)
- Potential benefit of continuous immunotherapies for secondary progressive multiple sclerosis (2017) (0)
- Advance Publication by J-STAGE (2018) (0)
- [Development of therapeutics for autoimmune disorders showing clinical and pathological variance]. (2009) (0)
- Time to reconsider the classification of multiple sclerosis (2022) (0)
- Structure-Activity Relationship Study of Neurokinin-3 Receptor Agonists (2013) (0)
- Autoimmune Encephalitis/Encephalopathy: Pathogenesis and Clinical Management (2017) (0)
- Analysis of PLP-specific T cells suggests T cell receptor CDR3 conservation among human encephalitogenic T cells (1994) (0)
- Donor T Cells Disease by Inducing Th2 Polarization of Graft-versus-Host Glycolipid Regulates Acute Stimulation of Host NKT Cells by Synthetic (2004) (0)
- Suppression of regulatory T cells by exosomes via LET-7I-IGF1R/TGFBR1 axis in multiple sclerosis (2017) (0)
- [113th Scientific Meeting of the Japanese Society of Internal Medicine: Symposium: Gut microbiota and diseases: Gut Microbiota and Multiple Sclerosis]. (2016) (0)
- Erratum: Another View of T Cell Antigen Recognition: Cooperative Engagement of Glycolipid Antigens by Va14Ja18 Natural TCR (Journal of Immunology (2003) 171 (4539-4551)) (2004) (0)
- Feline immunodeficiency virus-associated neuropathological alterations induced by inflammatory cytokines (1998) (0)
- Contents, Vol. 83, 1987 (1987) (0)
- Neurokinin 3 receptor-selective agonist, senktide, decreases core temperature in Japanese Black cattle. (2020) (0)
- A T cell receptor CDR3 peptide that enhances both MBP- and PLP- induced EAE: A possible existence of common regulatory cells (1994) (0)
- [Regulation of experimental autoimmune encephalomyelitis by NK and NKT cells]. (2002) (0)
- Suppression of Lymphocyte Spontaneous Response by Proteolipid Protein Peptide HAM/TSP* Proliferative in Patients with (1994) (0)
- Gut Microbiota: A Possible Role in the Pathogenesis of Multiple Sclerosis (2016) (0)
- Launch of new review/editing system for Clinical and Experimental Neuroimmunology (2013) (0)
- CD11c on NK Cells Mirrors the Temporal Disease Activity of Multiple Sclerosis (2007) (0)
- Neuromyelitis optica and human T‐cell lymphotropic virus type 1‐associated myelopathy/tropical spastic paraparesis: Pathogenesis and emerging therapies (2017) (0)
- The role of MR-1 restricted MAIT cells in murine models of arthritis (137.28) (2009) (0)
- F.101. Small Heat Shock Protein αB-Crystallin, a Candidate Autoantigen in Multiple Sclerosis, Stimulates Proinflammatory Cytokine Production (2009) (0)
- Two different human Th17 cells defined by chemokine receptor expression (2008) (0)
- [Cell-mediated immunity in neuroimmunological disorders]. (2015) (0)
- Translational research and MS/NMOSD (2018) (0)
- [Multiple sclerosis: a disease mediated by autoimmune mechanism]. (2008) (0)
- OR.58. Expression of the Orphan Nuclear Receptor NR4A2 is Required for IL-17 Production by Th17 Cells (2009) (0)
- NLRP3 “inflammasome” plays a central role in “inflammatory” demyelination of multiple sclerosis (2013) (0)
- Acinic Cell Carcinoma of the Parotid Gland. Fine Needle Aspiration Cytology Findings (2015) (0)
- [Immunopathogenesis of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)]. (2018) (0)
- Th 1 Responses In Vivo Receptor-Specific Inhibition of Autoreactive 1 Autoimmune Encephalomyelitis : NPY Neuropeptide Y ( NPY ) Suppresses Experimental (2003) (0)
- MOLECULAR MECHANISMS UNDERLYING THERAPEUTIC EFFECTS OF INTERFERON-BETA IN MULTIPLE SCLEROSIS (2011) (0)
- Double-negative suppressor T cells against encephalitogenic T cell clones (1993) (0)
- Ghrelin Suppression of Autoimmune Encephalomyelitis (2012) (0)
- [TCR CDR3 motif expression in PLP specific T cell from patients with multiple sclerosis]. (1995) (0)
- Editorial: Neuroimmunology (2019) (0)
- [Multiple Sclerosis and Gut Microbiome: Current Research and Perspective]. (2021) (0)
- Neuropilin‐1 (NRP1) expression distinguishes self‐reactive helper T cells in systemic autoimmune disease (2022) (0)
- Vascular endothelial growth factor: A potential target of therapy in neuromyelitis optica? (2015) (0)
- Rheumatoid arthritis and other inflammatory joint diseases (animal models) (PP-037) (2010) (0)
- Pathogenesis of Multiple Sclerosis Metalloproteinase-9 and Osteopontin in the T Cells Produce Matrix + CCR 5 + CCR 2 (2012) (0)
- Derives de glycolipide, leur procede de production, intermediaires pour la synthese associee, et procede de production desdits intermediaires (2004) (0)
- Differential Effects of Aire Gene Deficiency on the Development of Autoimmune Encephalomyelitis Induced by Two Representative Myelin Peptides (2007) (0)
- Functional Analysis of Carcinoembryonic Antigen-related Cellular Adhesion Molecule 1 in Experimental Autoimmune Encephalomyelitis (2007) (0)
- Ninja: Normal-appearing imaging, neuroimmunologically justified, autoimmune-mediated encephalomyelitis; a distinctive subgroup hidden in the multiple sclerosis population (2017) (0)
- A multiple sclerosis patient-oriented multiomics analysis tells us where to go next: Commentary for: “Alterations of host-gut microbiome interactions in multiple sclerosis” (2022) (0)
- Sensitization of superior dominant peptide may eradicate multiple sclerosis throughout by sequential induction of stabilized hybrid regulatory T cells with diverse antigen-specificity and tissue-repair capacity (2017) (0)
- [Multiple Sclerosis and Commensal Gut Flora]. (2016) (0)
- OR.59. Abnormally Differentiated CD28null TIM-3− Th1 Cells Specifically Respond to αB-Crystallin in Multiple Sclerosis (2008) (0)
- Circulating exosomes cause loss of immunological balance in multiple sclerosis (2018) (0)
- W1794 Activation of Invariant NKT Cells Prevents the Growth of Colitis-Associated Colorectal Cancers in Mice (2010) (0)
- Inflammatory Bowel Response against NKT Cells Are Critical for the Initiation of an (2005) (0)
- Analysis of PLP-specific T cells in MS: Identification of PLP 95-116 as HLA-DR2 associated determinant (1994) (0)
- F.26. Alteration of Gut Flora Ameliorates Experimental Autoimmune Encephalomyelitis in Association with Contraction of Inflammatory Th17 Cells (2008) (0)
- Circulating exosomes suppress the induction of regulatory T cells via let-7i in multiple sclerosis (2018) (0)
- Development of novel neurokinin-3 receptor agonists that potently stimulate the GnRH pulse generator (2014) (0)
- Invariant NKT Cells and Immune Regulation in Multiple Sclerosis (2007) (0)
- [Experimental animal model of multiple sclerosis--transverse investigation of MS pathogenesis for therapeutic intervention]. (2014) (0)
- Corpus Callosum Area: A Reliable and Feasible Neuroimaging Marker of Cognitive Impairment in Multiple Sclerosis (2022) (0)
- Regulation of Experimental Autoimmune Encephalomyelitis by Gut Resident T cells (2014) (0)
- Suppression of lymphocyte spontaneous proliferative response by proteolipid protein peptide in patients with HAM/TSP (1994) (0)
- Flow cytometric analysis of an immature oligodendrocyte line with a mixed oligodendrocyte-astrocyte phenotype (1991) (0)
- Satralizumab: An Interleukin-6 Receptor-blocking Therapy for Neuromyelitis Optica Spectrum Disorder (2021) (0)
- NINJA; Normal-appearing Imaging-associated, Neuroimmunologically Justified, Autoimmune Encephalomyelitis (P5.383) (2018) (0)
- 5) Gut Microbiota and Multiple Sclerosis (2016) (0)
- The Role of MR-1 Restricted MAIT Cells in the Pathogenesis of Murine Models of Arthritis (2010) (0)
- [Programs for Continuing Medical Education: A session; 6. Advances in basic research and therapy of multiple sclerosis]. (2015) (0)
- Cannabinoid-mediated immunosuppression in experimental allergic encephalomyelitis (2006) (0)
- To the understanding of neuroinflammation and beyond (2016) (0)
- IFN-gamma inhibits inflammatory arthritis via suppression of mast cell activation. (129.23) (2007) (0)
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What Schools Are Affiliated With Takashi Yamamura?
Takashi Yamamura is affiliated with the following schools:
