Takehiko Nohmi

Q: What Schools Are Affiliated With Takehiko Nohmi

Takehiko Nohmi is affiliated with the following schools: Hokkaido University, Tohoku University, University of Tokyo, Institute of Science Tokyo, Massachusetts Institute of Technology, Kyoto University, University of Texas Southwestern Medical Center

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Takehiko Nohmi

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Computer Science

Takehiko Nohmi's Degrees

PhD Computer Science University of Tokyo
Masters Computer Science University of Tokyo
Bachelors Computer Science University of Tokyo

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Takehiko Nohmi's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

The Y-family of DNA polymerases. (2001) (846)
Primary mutagenicity screening of food additives currently used in Japan. (1984) (654)
Genetic polymorphisms and alternative splicing of the hOGG1 gene, that is involved in the repair of 8-hydroxyguanine in damaged DNA (1998) (482)
The dinB gene encodes a novel E. coli DNA polymerase, DNA pol IV, involved in mutagenesis. (1999) (455)
RecA-mediated cleavage activates UmuD for mutagenesis: mechanistic relationship between transcriptional derepression and posttranslational activation. (1988) (394)
Mmh/Ogg1 gene inactivation results in accumulation of 8-hydroxyguanine in mice. (2000) (354)
Multiple pathways for SOS-induced mutagenesis in Escherichia coli: an overexpression of dinB/dinP results in strongly enhancing mutagenesis in the absence of any exogenous treatment to damage DNA. (1997) (338)
Sensitive method for the detection of mutagenic nitroarenes and aromatic amines: new derivatives of Salmonella typhimurium tester strains possessing elevated O-acetyltransferase levels. (1990) (315)
Cloning of a human homolog of the yeast OGG1 gene that is involved in the repair of oxidative DNA damage (1997) (265)
Other transgenic mutation assays: A new transgenic mouse mutagenesis test system using Spi− and 6‐thioguanine selections (1996) (212)
Recent advances in the protocols of transgenic mouse mutation assays. (2000) (205)
Recommendations for the performance of bacterial mutation assays. (1994) (201)
Roles of chromosomal and episomal dinB genes encoding DNA pol IV in targeted and untargeted mutagenesis in Escherichia coli (2001) (198)
Mutagenicity of 30 chemicals in Salmonella typhimurium strains possessing different nitroreductase or O-acetyltransferase activities. (1991) (190)
Mutagenicity testing for chemical risk assessment: update of the WHO/IPCS Harmonized Scheme. (2009) (185)
A sensitive method for the detection of mutagenic nitroarenes: construction of nitroreductase-overproducing derivatives of Salmonella typhimurium strains TA98 and TA100. (1989) (181)
Specificity and sensitivity of Salmonella typhimurium YG1041 and YG1042 strains possessing elevated levels of both nitroreductase and acetyltransferase activity. (1993) (167)
The β clamp targets DNA polymerase IV to DNA and strongly increases its processivity (2000) (164)
Escherichia coli DNA Polymerase IV Mutator Activity: Genetic Requirements and Mutational Specificity (2000) (161)
In vivo transgenic mutation assays. (2003) (154)
Environmental stress and lesion-bypass DNA polymerases. (2006) (153)
Mutations in UVSSA cause UV-sensitive syndrome and destabilize ERCC6 in transcription-coupled DNA repair (2012) (149)
Dominant negative umuD mutations decreasing RecA-mediated cleavage suggest roles for intact UmuD in modulation of SOS mutagenesis. (1990) (124)
DinB Upregulation Is the Sole Role of the SOS Response in Stress-Induced Mutagenesis in Escherichia coli (2009) (117)
Genotoxic responses to titanium dioxide nanoparticles and fullerene in gpt delta transgenic MEF cells (2009) (116)
Evaluation of the genotoxicity of stevioside and steviol using six in vitro and one in vivo mutagenicity assays. (1996) (108)
Involvement of Cys69 residue in the catalytic mechanism of N-hydroxyarylamine O-acetyltransferase of Salmonella typhimurium. Sequence similarity at the amino acid level suggests a common catalytic mechanism of acetyltransferase for S. typhimurium and higher organisms. (1992) (106)
Report of the IWGT working group on strategies and interpretation of regulatory in vivo tests I. Increases in micronucleated bone marrow cells in rodents that do not indicate genotoxic hazards. (2007) (102)
Modulation of oxidative mutagenesis and carcinogenesis by polymorphic forms of human DNA repair enzymes. (2005) (98)
Development of high sensitive umu test system: rapid detection of genotoxicity of promutagenic aromatic amines by Salmonella typhimurium strain NM2009 possessing high O-acetyltransferase activity. (1995) (95)
In vivo transgenic mutation assays (2000) (90)
Recent advances in the construction of bacterial genotoxicity assays. (1997) (89)
Genotoxicity of nano/microparticles in in vitro micronuclei, in vivo comet and mutation assay systems (2009) (88)
Adenine excisional repair function of MYH protein on the adenine:8-hydroxyguanine base pair in double-stranded DNA. (2000) (86)
Salmonella typhimurium has two homologous but different umuDC operons: cloning of a new umuDC-like operon (samAB) present in a 60-megadalton cryptic plasmid of S. typhimurium (1991) (85)
New tester strains of Salmonella typhimurium highly sensitive to mutagenic nitroarenes. (1987) (84)
Enhanced spontaneous and benzo(a)pyrene-induced mutations in the lung of Nrf2-deficient gpt delta mice. (2007) (78)
Construction and characterization of mutants of Salmonella typhimurium deficient in DNA repair of O6-methylguanine (1995) (77)
Highly sensitive umu test system for the detection of mutagenic nitroarenes in Salmonella typhimurium NM3009 having high O‐acetyltransferase and nitroreductase activities (1993) (75)
Site-specific in vivo mutagenicity in the kidney of gpt delta rats given a carcinogenic dose of ochratoxin A. (2011) (73)
Erroneous incorporation of oxidized DNA precursors by Y‐family DNA polymerases (2003) (72)
Spectra of gpt mutations in ethylnitrosourea‐treated and untreated transgenic mice (1999) (72)
Overproduction of Escherichia coli DNA polymerase DinB (Pol IV) inhibits replication fork progression and is lethal (2008) (71)
Thresholds of Genotoxic and Non-Genotoxic Carcinogens (2018) (69)
Parp-1 deficiency causes an increase of deletion mutations and insertions/rearrangements in vivo after treatment with an alkylating agent (2005) (68)
New tester strains of Salmonella typhimurium lacking O6-methylguanine DNA methyltransferases and highly sensitive to mutagenic alkylating agents. (1997) (68)
Nucleotide sequence of Salmonella typhimurium nitroreductase gene. (1990) (67)
Heavy‐ion‐induced mutations in the gpt delta transgenic mouse: Comparison of mutation spectra induced by heavy‐ion, X‐ray, and γ‐ray radiation (2002) (67)
Spi− selection: An efficient method to detect γ‐ray‐induced deletions in transgenic mice (1999) (64)
Molecular nature of intrachromosomal deletions and base substitutions induced by environmental mutagens (2005) (64)
Novel transgenic rat for in vivo genotoxicity assays using 6‐thioguanine and Spi− selection (2003) (61)
Processing of DNA lesions by archaeal DNA polymerases from Sulfolobus solfataricus. (2003) (60)
Report of the IWGT working group on strategy/interpretation for regulatory in vivo tests II. Identification of in vivo-only positive compounds in the bone marrow micronucleus test. (2007) (59)
DNA polymerase κ-dependent DNA synthesis at stalled replication forks is important for CHK1 activation (2013) (59)
Characterization of mutations induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in the colon of gpt delta transgenic mouse: novel G:C deletions beside runs of identical bases. (2000) (55)
Purification and Characterization of Wild-type and Mutant “Classical” Nitroreductases of Salmonella typhimurium (1998) (55)
In vivo mutagenicity and initiation following oxidative DNA lesion in the kidneys of rats given potassium bromate (2006) (55)
Sensitivity of Salmonella typhimurium YG1024 to urine mutagenicity caused by cigarette smoking. (1990) (54)
Miscoding properties of 2'-deoxyinosine, a nitric oxide-derived DNA Adduct, during translesion synthesis catalyzed by human DNA polymerases. (2008) (54)
Radiation induced COX-2 expression and mutagenesis at non-targeted lung tissues of gpt delta transgenic mice (2012) (53)
Synthetic Activity of Sso DNA Polymerase Y1, an Archaeal DinB-like DNA Polymerase, Is Stimulated by Processivity Factors Proliferating Cell Nuclear Antigen and Replication Factor C* (2001) (50)
Involvement of Y-Family DNA Polymerases in Mutagenesis Caused by Oxidized Nucleotides in Escherichia coli (2006) (50)
In vivo mutational analysis of liver DNA in gpt delta transgenic rats treated with the hepatocarcinogens N‐nitrosopyrrolidine, 2‐amino‐3‐methylimidazo[4,5‐f]quinoline, and di(2‐ethylhexyl)phthalate (2005) (49)
Molecular nature of ultraviolet B light-induced deletions in the murine epidermis. (2001) (49)
Arabidopsis thaliana Y-family DNA polymerase eta catalyses translesion synthesis and interacts functionally with PCNA2. (2008) (49)
Mechanisms of chemopreventive effects of 8-methoxypsoralen against 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced mouse lung adenomas. (2005) (49)
Cloning and characterization of the Salmonella typhimurium ada gene, which encodes O6-methylguanine-DNA methyltransferase (1991) (47)
DNA polymerases involved in the incorporation of oxidized nucleotides into DNA: their efficiency and template base preference. (2010) (45)
Spontaneous mutant frequency of lacZ gene in spleen of transgenic mouse increases with age. (1995) (45)
Construction of mutants of Salmonella typhimurium deficient in 8-hydroxyguanine DNA glycosylase and their sensitivities to oxidative mutagens and nitro compounds. (1997) (44)
New method for gene disruption in Salmonella typhimurium: construction and characterization of an ada-deletion derivative of Salmonella typhimurium TA1535 (1993) (43)
IL-10 deficiency leads to somatic mutations in a model of IBD. (2006) (43)
Possible participation of oxidative stress in causation of cell proliferation and in vivo mutagenicity in kidneys of gpt delta rats treated with potassium bromate. (2009) (43)
Structural insight into dynamic bypass of the major cisplatin‐DNA adduct by Y‐family polymerase Dpo4 (2010) (42)
Mutagenicity of 2-amino-1-methyl-6-phenylimidazo [4,5-b]pyridine (PhIP) in the new gpt delta transgenic mouse. (1999) (40)
Difference in tumor incidence and other tissue responses to polyetherurethanes and polydimethylsiloxane in long-term subcutaneous implantation into rats. (1992) (40)
Semi-quantitative evaluation of genotoxic activity of chemical substances and evidence for a biological threshold of genotoxic activity. (2000) (40)
Mutagenic potency of Helicobacter pylori in the gastric mucosa of mice is determined by sex and duration of infection (2010) (39)
Molecular mechanisms underlying ochratoxin A-induced genotoxicity: global gene expression analysis suggests induction of DNA double-strand breaks and cell cycle progression. (2013) (39)
Low dose genotoxicity of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx) in gpt delta transgenic mice. (2003) (39)
Heavy‐ion‐induced mutations in the gpt delta transgenic mouse: Effect of p53 gene knockout (2002) (39)
Genetic Analysis of Repair and Damage Tolerance Mechanisms for DNA-Protein Cross-Links in Escherichia coli (2009) (37)
Molecular characterization of mitomycin C-induced large deletions and tandem-base substitutions in the bone marrow of gpt delta transgenic mice. (2003) (36)
Ochratoxin A induces DNA double-strand breaks and large deletion mutations in the carcinogenic target site of gpt delta rats. (2014) (36)
New sublines of Chinese hamster CHL stably expressing human NAT1 or NAT2 N-acetyltransferases or Salmonella typhimurium O-acetyltransferase: comparison of the sensitivities to nitroarenes and aromatic amines using the in vitro micronucleus test. (1994) (36)
Efficient and erroneous incorporation of oxidized DNA precursors by human DNA polymerase eta. (2007) (36)
Transgenic rat models for mutagenesis and carcinogenesis (2017) (35)
Integration of In Vivo Genotoxicity and Short-term Carcinogenicity Assays Using F344 gpt Delta Transgenic Rats: In Vivo Mutagenicity of 2,4-Diaminotoluene and 2,6-Diaminotoluene Structural Isomers (2009) (35)
UVB‐induced gpt mutations in the skin of gpt delta transgenic mice (1999) (35)
Targeted disruption of the gene encoding the classical nitroreductase enzyme in Salmonella typhimurium Ames test strains TA1535 and TA1538. (1997) (35)
Mutagenicity of wood smoke condensates in the Salmonella/microsome assay. (1991) (35)
A sensitive umu test system for the detection of mutagenic nitroarenes in Salmonella typhimurium NM1011 having a high nitroreductase activity. (1992) (34)
[Mutagenicity tests on organic chemical contaminants in city water and related compounds. I. Bacterial mutagenicity tests]. (1985) (33)
The steric gate amino acid tyrosine 112 is required for efficient mismatched-primer extension by human DNA polymerase kappa. (2009) (33)
Absence of in vivo genotoxicity of 3-monochloropropane-1,2-diol and associated fatty acid esters in a 4-week comprehensive toxicity study using F344 gpt delta rats. (2014) (33)
Comprehensive toxicity study of safrole using a medium-term animal model with gpt delta rats. (2011) (32)
Gpt delta transgenic mouse: a novel approach for molecular dissection of deletion mutations in vivo. (2004) (31)
Possible involvement of genotoxic mechanisms in estragole-induced hepatocarcinogenesis in rats (2012) (31)
Role of p53 in the progression from ochratoxin A-induced DNA damage to gene mutations in the kidneys of mice. (2015) (31)
Potent genotoxicity of aminophenylnorharman, formed from non-mutagenic norharman and aniline, in the liver of gpt delta transgenic mouse. (2003) (30)
Effects of the umuDC, mucAB, and samAB operons on the mutational specificity of chemical mutagenesis in Escherichia coli: II. Base substitution mutagenesis. (1994) (30)
Cell cycle progression, but not genotoxic activity, mainly contributes to citrinin-induced renal carcinogenesis. (2013) (29)
Characterization of three forms of cytochrome P-450 inducible by 3-methylcholanthrene in Golden hamster livers with special reference to aflatoxin B1 activation. (1989) (28)
Replication of 2-hydroxyadenine-containing DNA and recognition by human MutSalpha. (2007) (28)
Mutations in Salmonella typhimurium and inactivation of Bacillus subtilis transforming DNA induced by phenylhydroxylamine derivatives. (1984) (28)
Regionally-targeted mutagenesis by metabolically-activated steviol: DNA sequence analysis of steviol-induced mutants of guanine phosphoribosyltransferase (gpt) gene of Salmonella typhimurium TM677. (1996) (28)
Difference in liver homogenates from Donryu, Fischer, Sprague-Dawley and Wistar strains of rat in the drug-metabolizing enzyme assay and the Salmonella/hepatic S9 activation test. (1982) (28)
New mutations in cloned Escherichia coli umuDC genes: novel phenotypes of strains carrying a umuC125 plasmid. (1991) (28)
Roles of Salmonella typhimurium umuDC and samAB in UV mutagenesis and UV sensitivity (1992) (27)
In vivo mutagenesis induced by benzo[a]pyrene instilled into the lung of gpt delta transgenic mice (2005) (27)
Comparison of the mutagenicity of aristolochic acid I and aristolochic acid II in the gpt delta transgenic mouse kidney. (2012) (27)
Mutations in the lungs of gpt delta transgenic mice following inhalation of diesel exhaust (2007) (27)
Comparison of the sensitivity of Salmonella typhimurium strains YG1024 and YG1012 for detecting the mutagenicity of aromatic amines and nitroarenes. (1993) (26)
Species difference in the metabolic activation of phenacetin by rat and hamster liver microsomes. (1983) (26)
Acrylamide genotoxicity in young versus adult gpt delta male rats. (2011) (26)
Specificity of replicative and SOS-inducible DNA polymerases in frameshift mutagenesis: mutability of Salmonella typhimurium strains overexpressing SOS-inducible DNA polymerases to 30 chemical mutagens. (2006) (26)
Roles of replicative and specialized DNA polymerases in frameshift mutagenesis: mutability of Salmonella typhimurium strains lacking one or all of SOS-inducible DNA polymerases to 26 chemicals. (2005) (25)
Critical amino acids in human DNA polymerases η and κ involved in erroneous incorporation of oxidized nucleotides (2009) (25)
Further characterization and validation of gpt delta transgenic mice for quantifying somatic mutations in vivo (2001) (25)
Detection of oxidative DNA damage, cell proliferation and in vivo mutagenicity induced by dicyclanil, a non-genotoxic carcinogen, using gpt delta mice. (2007) (25)
Light‐dependent mutagenesis by benzo[a]pyrene is mediated via oxidative DNA damage (2005) (24)
Effect of Atm Disruption on Spontaneously Arising and Radiation-Induced Deletion Mutations in Mouse Liver (2003) (24)
Possible involvement of sulfotransferase 1A1 in estragole-induced DNA modification and carcinogenesis in the livers of female mice. (2012) (24)
Evaluation of in vivo genotoxicity induced by N‐ethyl‐N‐nitrosourea, benzo[a]pyrene, and 4‐nitroquinoline‐1‐oxide in the Pig‐a and gpt assays (2013) (24)
Role of Parp-1 in suppressing spontaneous deletion mutation in the liver and brain of mice at adolescence and advanced age. (2009) (24)
Inhibition of translesion DNA polymerase by archaeal reverse gyrase (2009) (23)
New Insight into Intrachromosomal Deletions Induced by Chrysotile in the gpt delta Transgenic Mutation Assay (2006) (23)
Mutant Cockayne syndrome group B protein inhibits repair of DNA topoisomerase I‐DNA covalent complex (2011) (23)
Escherichia coli DNA polymerase III is responsible for the high level of spontaneous mutations in mutT strains (2012) (23)
Genomic integration of lambda EG10 transgene in gpt delta transgenic rodents (2015) (23)
Strategies in case of positive in vivo results in genotoxicity testing. (2011) (23)
In vivo genotoxicity of methyleugenol in gpt delta transgenic rats following medium-term exposure. (2013) (22)
In vivo positive mutagenicity of 1,4-dioxane and quantitative analysis of its mutagenicity and carcinogenicity in rats (2018) (22)
Deletion and single nucleotide substitution at G:C in the kidney of gpt delta transgenic mice after ferric nitrilotriacetate treatment (2006) (22)
Efficient detection of deletions induced by a single treatment of mitomycin C in transgenic mouse gpt delta using the Spi− selection (1999) (20)
Radiation Dose-Rate Effect on Mutation Induction in Spleen and Liver of gpt delta Mice (2010) (20)
Combined genotoxic effects of radiation and a tobacco-specific nitrosamine in the lung of gpt delta transgenic mice. (2007) (20)
Catalytic and non‐catalytic roles of DNA polymerase κ in the protection of human cells against genotoxic stresses (2015) (20)
Error-Prone Translesion DNA Synthesis by Escherichia coli DNA Polymerase IV (DinB) on Templates Containing 1,2-dihydro-2-oxoadenine (2010) (20)
Differential effects of low- and high-dose X-rays on N-ethyl-N-nitrosourea-induced mutagenesis in thymocytes of B6C3F1 gpt-delta mice. (2008) (20)
Mutational specificities of brominated DNA adducts catalyzed by human DNA polymerases. (2011) (19)
Chemopreventive effects of silymarin against 1,2-dimethylhydrazine plus dextran sodium sulfate-induced inflammation-associated carcinogenicity and genotoxicity in the colon of gpt delta rats. (2011) (18)
N-hydroxyarylamine O-acetyltransferase of Salmonella typhimurium: proposal for a common catalytic mechanism of arylamine acetyltransferase enzymes. (1994) (18)
Inhibitory effects of caraway (Carum carvi L. ) and its component on N-methyl-N'-nitro-N-nitrosoguanidine-induced mutagenicity. (2006) (18)
Purification and characterization of a form of cytochrome P-450 with high specificity for aflatoxin B1 from 3-methylcholanthrene-treated hamster liver. (1986) (18)
Lack of genotoxic mechanisms in early‐stage furan‐induced hepatocellular tumorigenesis in gpt delta rats (2017) (18)
Impact of Ribonucleotide Backbone on Translesion Synthesis and Repair of 7,8-Dihydro-8-oxoguanine* (2016) (18)
In vivo evidence that DNA polymerase kappa is responsible for error-free bypass across DNA cross-links induced by mitomycin C. (2014) (17)
Phenylalanine 171 is a molecular brake for translesion synthesis across benzo[a]pyrene-guanine adducts by human DNA polymerase kappa. (2011) (17)
MX, a by‐product of water chlorination, lacks in vivo genotoxicity in gpt delta mice but inhibits gap junctional intercellular communication in rat WB cells (2006) (17)
DNA polymerase kappa protects human cells against MMC-induced genotoxicity through error-free translesion DNA synthesis (2017) (17)
Suppression of chemically induced and spontaneously occurring oxidative mutagenesis by three alleles of human OGG1 gene encoding 8-hydroxyguanine DNA glycosylase. (2004) (16)
Estimation of the frequency of inherited germline mutations by whole exome sequencing in ethyl nitrosourea-treated and untreated gpt delta mice (2016) (16)
Oxidative DNA damage and in vivo mutagenicity caused by reactive oxygen species generated in the livers of p53‐proficient or ‐deficient gpt delta mice treated with non‐genotoxic hepatocarcinogens (2013) (16)
Oxidative DNA damage and reporter gene mutation in the livers of gpt delta rats given non‐genotoxic hepatocarcinogens with cytochrome P450‐inducible potency (2010) (16)
Lack of in vivo mutagenicity and oxidative DNA damage by flumequine in the livers of gpt delta mice (2006) (15)
In vivo mutagenicity of arsenite in the livers of gpt delta transgenic mice. (2014) (15)
Specificity of mutations induced by incorporation of oxidized dNTPs into DNA by human DNA polymerase eta. (2008) (15)
Chemically-Induced DNA Damage, Mutagenesis, and Cancer (2018) (15)
Combined application of comprehensive analysis for DNA modification and reporter gene mutation assay to evaluate kidneys of gpt delta rats given madder color or its constituents (2014) (15)
Biochemical evidence of a physical interaction between Sulfolobus solfataricus B-family and Y-family DNA polymerases (2007) (15)
Mutagenesis induced by oxidized DNA precursors: roles of Y family DNA polymerases in Escherichia coli. (2005) (15)
The role of DNA polymerase ζ in translesion synthesis across bulky DNA adducts and cross-links in human cells. (2016) (14)
Preferential induction of AT-TA transversion, but not deletions, by chlorambucil at the hisG428 site of Salmonella typhimurium TA102. (1992) (14)
Duration of S9 activity in agar overlay. (1981) (14)
Miscoding properties of 8-chloro-2'-deoxyguanosine, a hypochlorous acid-induced DNA adduct, catalysed by human DNA polymerases. (2013) (14)
In vivo mutagenesis in the lungs of gpt‐delta transgenic mice treated intratracheally with 1,6‐dinitropyrene (2006) (14)
Development of a Medium-term Animal Model Using gpt Delta Rats to Evaluate Chemical Carcinogenicity and Genotoxicity (2013) (13)
Reporter gene transgenic mice as a tool for analyzing the molecular mechanisms underlying experimental carcinogenesis. (2001) (12)
Metabolic activation of 2,4-xylidine and its mutagenic metabolite. (1983) (12)
Past, Present and Future Directions of gpt delta Rodent Gene Mutation Assays. (2016) (12)
Translesional DNA Synthesis through a C8-Guanyl Adduct of 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in Vitro (2009) (12)
Chemical structure-related mechanisms underlying in vivo genotoxicity induced by nitrofurantoin and its constituent moieties in gpt delta rats. (2015) (11)
Genomic structure and chromosomal localization of the mouse Ogg1 gene that is involved in the repair of 8-hydroxyguanine in DNA damage (2009) (11)
Evaluation of the Genotoxicity of Aristolochic Acid in the Kidney and Liver of F344 gpt delta Transgenic Rat Using a 28-Day Repeated-dose Protocol: A Collaborative Study of the gpt delta Transgenic Rat Mutation Assay (2012) (11)
Novel DNA Polymerases and Novel Genotoxicity Assays (2007) (11)
New O-acetyltransferase-deficient Ames Salmonella strains generated by specific gene disruption. (1999) (11)
Spontaneous Mutagenesis in Rodents: Spontaneous Gene Mutations Identified by Neutral Reporter Genes in gpt Delta Transgenic Mice and Rats (2009) (10)
Effects of O 6‐alkylguanine‐DNA alkyltransferase deficiency in Escherichia coli as the host for the detection of mutations in lacI transgenic mice (1999) (10)
Sensitivity of human cells expressing low-fidelity or weak-catalytic-activity variants of DNA polymerase ζ to genotoxic stresses. (2016) (10)
Combined ascorbic acid and sodium nitrite treatment induces oxidative DNA damage-associated mutagenicity in vitro, but lacks initiation activity in rat forestomach epithelium. (2008) (10)
Validation study of the combined repeated-dose toxicity and genotoxicity assay using gpt delta rats (2015) (10)
Restoration of Mismatch Repair Functions in Human Cell Line Nalm-6, Which Has High Efficiency for Gene Targeting (2013) (10)
Possible Mechanisms Underlying Genotoxic Thresholds: DNA Repair and Translesion DNA Synthesis (2016) (10)
Dose-dependent de novo germline mutations detected by whole-exome sequencing in progeny of ENU-treated male gpt delta mice. (2016) (10)
Mutant Frequency is not Increased in Mice Orally Exposed to Sodium Dichromate (2019) (10)
Limited ability of DNA polymerase kappa to suppress benzo[a]pyrene‐induced genotoxicity in vivo (2017) (10)
Structures and biological properties of DNA adducts derived from N-nitroso bile acid conjugates. (2005) (9)
Construction of a new system for separate expression of mutagenesis proteins: the abilities to promote UV mutagenesis and interchangeability of MucA', MucB, SamA' and SamB proteins in Salmonella typhimurium. (1996) (9)
Mechanism of metabolic activation of the analgetic bucetin to bacterial mutagens by hamster liver microsomes. (1985) (9)
Embryonic lethality in mice lacking mismatch-specific thymine DNA glycosylase is partially prevented by DOPS, a precursor of noradrenaline. (2012) (9)
Involvement of umuDCST genes in nitropyrene-induced -CG frameshift mutagenesis at the repetitive CG sequence in the hisD3052 allele of Salmonella typhimurium (2004) (9)
Improvement of the Spi‐ assay for mutations in gpt delta mice by including magnesium ions during plaque formation (2003) (9)
In vivo evidence that phenylalanine 171 acts as a molecular brake for translesion DNA synthesis across benzo[a]pyrene DNA adducts by human DNA polymerase κ. (2014) (9)
DNA polymerase kappa counteracts inflammation‐induced mutagenesis in multiple organs of mice (2019) (9)
A newly established GDL1 cell line from gpt delta mice well reflects the in vivo mutation spectra induced by mitomycin C. (2006) (9)
Antigenotoxic effects of p53 on spontaneous and ultraviolet light B–induced deletions in the epidermis of gpt delta transgenic mice (2011) (9)
Amino acid similarities to other proteins offer insights into roles of UmuD and UmuC in mutagenesis. (1989) (9)
Development of a Bacterial Hyper-sensitive Tester Strain for Specific Detection of the Genotoxicity of Polycyclic Aromatic Hydrocarbons (2006) (8)
Specific disruption of samAB genes in a 60-megadalton cryptic plasmid of Salmonella typhimurium. (1995) (8)
In vivo genotoxicity of 1-methylnaphthalene from comprehensive toxicity studies with B6C3F1 gpt delta mice. (2012) (8)
[Mutagenicity of steviol: an analytical approach using the Southern blotting system]. (1988) (8)
Mechanism of species differences in N-hydroxyphenacetin mutagenicity: the role of deacetylation by rat and hamster liver microsomes. (1984) (8)
Roles of the mutagenesis proteins SamA'B and MucA'B in chemically induced frameshift mutagenesis in Salmonella typhimurium hisD3052. (1998) (8)
The application of hepatic P450 reductase null gpt delta mice in studying the role of hepatic P450 in genotoxic carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced mutagenesis (2012) (7)
Effects of co-treatment of dextran sulfate sodium and MeIQx on genotoxicity and possible carcinogenicity in the colon of p53-deficient mice. (2010) (7)
A medium-term gpt delta rat model as an in vivo system for analysis of renal carcinogenesis and the underlying mode of action. (2015) (7)
Differential mutagenicities of triamino benzenes against Salmonella typhimurium TA98 in the presence of S9 fractions from polychlorinated biphenyls-, phenobarbital- or 3-methylcholanthrene-pretreated rats, hamsters and mice. (1979) (7)
Evaluation of In Vivo Mutagenicity by 2,4-Diaminotoluene and 2,6-Diaminotoluene in Liver of F344 gpt delta Transgenic Rat Dosed for 28 Days: A Collaborative Study of the gpt delta Transgenic Rat Mutation Assay (2012) (7)
Enhancing effects of carbon tetrachloride on in vivo mutagenicity in the liver of mice fed 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx). (2010) (6)
Effects of the umuDC, mucAB, and samAB operons on the mutational specificity of chemical mutagenesis in Escherichia coli: I. Frameshift mutagenesis. (1994) (6)
Metabolic activation of phenacetin and phenetidine by several forms of cytochrome P-450 purified from liver microsomes of rats and hamsters. (1987) (6)
Evaluation of the genotoxicity of tamoxifen in the liver and kidney of F344 gpt delta transgenic rat in 3-week and 13-week repeated dose studies. (2013) (6)
Environmental Stress and (2006) (6)
Improvement and validation of a medium-term gpt delta rat model for predicting chemical carcinogenicity and underlying mode of action. (2014) (6)
[Metabolic activation of p-nitrotoluene and trichloroethylene by rat-liver S9 or mouse-liver S9 fractions in Salmonella typhimurium strains (author's transl)]. (1981) (6)
Selected abstract of Papers presented at the 13th Annual Meeting of the Environmental Mutagen Society of Japan 12–13 October 1984, Tokyo (Japan)Mutagenicity tests on phenacetin-related compounds in cultured mammalian cells (1985) (6)
Involvement of mismatch repair proteins in adaptive responses induced by N-methyl-N'-nitro-N-nitrosoguanidine against γ-induced genotoxicity in human cells. (2011) (6)
Hydrogen peroxide-induced microsatellite instability in the Escherichia coli K-12 endogenous tonB gene. (2003) (6)
Possible Mechanisms of Practical Thresholds for Genotoxicity (2008) (6)
In Vivo Mutagenesis Caused by Diesel Exhaust in the Testis of gpt delta Transgenic Mice (2009) (5)
The effectiveness of the O(6)-alkylguanine-DNA alkyltransferase encoded by the ogt(ST) gene from S. typhimurium in protection against alkylating drugs, resistance to O(6)-benzylguanine and sensitisation to dibromoalkane genotoxicity. (2001) (5)
Alterations in the mutagenicity and mutation spectrum induced by benzo[a]pyrene instilled in the lungs of gpt delta mice of various ages (2015) (5)
Genotoxicity of phenacetin in the kidney and liver of Sprague-Dawley gpt delta transgenic rats in 26-week and 52-week repeated-dose studies. (2014) (5)
Improvement and Evaluation of High Throughput Fluctuation Ames Test Using 384-well Plate with Salmonella typhimurium TA100 and TA98 (2009) (5)
2nd International Symposium on Genotoxic and Carcinogenic Thresholds (2008) (5)
Mutation Spectra in Cisplatin- and Transplatin-treated GDL1 Cells Clarified the Different Mode of Action of These Compounds in Mammalian Cells (2007) (4)
In vivo Approaches to Study Mechanism of Action of Genotoxic Carcinogens (2008) (4)
Stability of S9 during frozen storage in Salmonella/S9 assays. (1980) (4)
Lack of in vivo mutagenicity of acetamide in a 13-week comprehensive toxicity study using F344 gpt delta rats. (2020) (4)
Mutagenicity of carcinogenic heterocyclic amines in Salmonella typhimurium YG strains and transgenic rodents including gpt delta (2021) (4)
Chemopreventive Effects of Nobiletin against Genotoxicity Induced by 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in the Lung of gpt delta Transgenic Mice (2006) (4)
in vivo Approaches to Identify Mutations and in vitro Research to Reveal Underlying Mechanisms of Genotoxic Thresholds (2012) (4)
Mutation induction by heavy-ion irradiation of gpt delta transgenic mice. (2000) (4)
Quantitative evaluation on the genotoxic potency of chemicals. (1991) (4)
Phosphorylation of protein phosphatase 2A facilitated an early stage of chemical carcinogenesis (2017) (3)
Greetings from The International Association of Environmental Mutagenesis and Genomics Societies (2015) (3)
Error-prone bypass patch by a low-fidelity variant of DNA polymerase zeta in human cells. (2021) (3)
Efficient method for mapping and characterizing structures of deletion mutations in gpt delta mice using Southern blot analysis with oligo DNA probes (2004) (3)
Modulatory Effects of Capsaicin on N-diethylnitrosamine (DEN)-induced Mutagenesis in Salmonella typhimurium YG7108 and DEN-induced Hepatocarcinogenesis in gpt Delta Transgenic Rats (2011) (3)
Oxidative-stress-driven mutagenesis in the small intestine of the gpt delta mouse induced by oral administration of potassium bromate. (2020) (3)
Evaluation of the in vivo Mutagenicity of Nickel Subsulfide in the Lung of F344 gpt delta Transgenic Rats Exposed by Intratracheal Instillation: A Collaborative Study for the gpt delta Transgenic Rat Mutation Assay (2012) (3)
DNA polymerase j-dependent DNA synthesis at stalled replication forks is important for CHK 1 activation (2013) (3)
New homozygous gpt delta transgenic rat strain improves an efficiency of the in vivo mutagenicity assay (2021) (3)
A Sensitive System (umu Test) for the Detection of Mutagenic Nitroarenes in Salmonella Typhimurium Strain Possessing Elevated Nitroreductase (1992) (3)
Change over time of the mutagenicity in the lungs of gpt delta transgenic mice by extract of airborne particles collected from ambient air in the Tokyo metropolitan area (2018) (3)
Characterization of mixed-function oxidases and purified cytochrome P-450 of livers of house musk shrew, Suncus murinus. (1988) (3)
Visualization of the interaction between archaeal DNA polymerase and uracil‐containing DNA by atomic force microscopy (2005) (3)
Genetic analyses of cellular functions required for UV mutagenesis in Escherichia coli. (1990) (3)
Impact of DNA polymerase ζ mutations on genotoxic thresholds of oxidative mutagens. (2018) (3)
P02: Carcinogenicity and in vivo mutagenicity of 1,4-dioxane in gpt delta rats (2009) (3)
Effects of 7, 8-benzoflavone and SKF 525-A on the enzyme-mediated mutagenicity of phenylenediamines. (1982) (2)
Development of a Bacterial Hypersensitive Tester Strain for Speciˆc Detection of the Genotoxicity of Polycyclic Aromatic Hydrocarbons (2006) (2)
Construction and Characterization of Mutants of Salmonella typhimurium Deﬁcient in DNA Repair of O 6 -Methylguanine (1995) (2)
Structural insight into dynamic bypass of the major cisplatin-DNA adduct by Y-family polymerase Dpo 4 (2010) (2)
[Development of novel genotoxicity assays by genetic engineering methods]. (2000) (2)
Effects of the scid mutation on X-ray-induced deletions in the brain and spleen of gpt delta mice (2020) (2)
Translesion DNA synthesis by Y-family DNA polymerases (2002) (2)
Chromosome aberrations induced by the non-mutagenic carcinogen acetamide involve in rat hepatocarcinogenesis through micronucleus formation in hepatocytes (2021) (2)
Alteration of Genome Structure Induced by Very Low Dose-Rate Irradiation in Mouse Tissues (2009) (2)
Development of Tester Strains Deficient in Nth/Nei DNA Glycosylases to Selectively Detect the Mutagenicity of Oxidized DNA Pyrimidines (2009) (2)
Establishment of New Strains of S. Typhimurium Highly Sensitive to Nitroarenes and Aromatic Amines: TA98 and TA100 Substrains with Rich Nitroreductase or Acetyltransferase Activities (1990) (1)
Lack of mutagenicity of tetramethylsuccinonitrile in Salmonella typhimurium TA strains. (1987) (1)
Multiple pathways for SOS-induced mutagenesis in Escherichia coli: An overexpression of dinBydinP results in strongly enhancing mutagenesis in the absence of any exogenous treatment to damage DNA (SOS responseyuntargeted mutagenesisyframeshift mutationsyinducible evolution) (1997) (1)
Comprehensive analysis of the general toxicity, genotoxicity, and carcinogenicity of 3-acetyl-2,5-dimethylfuran in male gpt delta rats. (2022) (1)
Effects of DNA polymerase kappa and mismatch repair on dose–responses of chromosome aberrations induced by three oxidative genotoxins in human cells (2020) (1)
Purification and interactions of the MucA’ and MucB proteins constituting the DNA polymerase RI (2019) (1)
Gpt delta transgenic mouse: A novel approach for molecular dissection of deletion mutations in vivo. (2004) (1)
Comparison of the frequencies of ENU-induced point mutations in male germ cells and inherited germline mutations in their offspring (2021) (1)
Mismatch-specific Thymine DNA Glycosylase (TDG) is Indispensable for Embryonic Development (2002) (1)
Mutagenicity test on stevioside and its aglycone, steviol (1987) (1)
Background data of 2-year-old male and female F344 gpt delta rats (2020) (1)
Cloning of Salmonella typhimurium genes for nitroreductase and acetyltransferase: construction of Salmonella highly sensitive to mutagenic nitroarenes (1988) (1)
Specificity of Salmonella typhimurium YG1041 and YG1042 strains possessing elevated levels of both nitroreductase and O-acetyltransferase activities (1992) (1)
Expression and Activity of Human DNA Polymerase η in Escherichia coli (2013) (1)
Nucleotide pool damage and its biological consequences. (2010) (1)
Characteristic mutations induced in the small intestine of Msh2-knockout gpt delta mice (2021) (1)
Antimutagenic effect of umuD mutant plasmids: isolation and characterization of umuD mutants reduced in their ability to promote UV mutagenesis in Escherichia coli. (1990) (1)
Cloning and nucleotide sequence of the ada gene of Salmonella typhimurium encoding O6-methylguanine-DNA methyltransferase (1991) (1)
Environmental health criteria for transgenic animal mutagenicity assays (2006) (1)
Translesion DNA synthesis and repair of oxidized ribonucleotide (2016) (0)
Dose-dependent Increase of Spi- Mutations in Atm-disrupted Mice Following X-irradiation (2000) (0)
Comparison of the frequencies of ENU-induced point mutations in male germ cells and inherited germline mutations in their offspring (2021) (0)
Past, Present, and Future Challenges of the International Association of Environmental Mutagenesis and Genomics Societies (IAEMGS) (2014) (0)
P-073 Partial restoration of UV-mutagenesis in a umuDC-deletion mutant of Escherichia coli with human DNA polymerase η(Poster presentation) : (2013) (0)
Development of new Salmonella tester strains hypersensitive to mutagenic alkylating agents (1993) (0)
Genetic analysis of the gpt gene of steviol-induced mutants of Salmonella typhimurium TM677 using the polymerase chain reaction (1992) (0)
The two umuDC-like operons, samAB and umuDCST, in Salmonella typhimurium: the umuDCST operon may reduce UV-mutagenesis-promoting ability of the samAB operon. (1993) (0)
Repair and damage tolerance mechanisms for DNA-protein crosslinks in Escherichia coli (2009) (0)
New homozygous gpt delta transgenic rat strain improves an efficiency of the in vivo mutagenicity assay (2021) (0)
Development of high-throughput genotoxicity assays(Toxicity Screening Strategy in Early Stage Drug Development : Current Situation and Perspective, Proceedings of the 32nd Annual Meeting) (2005) (0)
Mutagenicity of 30 chemicals and human urine specimens in S. typhimurium strains with various nitroreductase or acetyltransferase activities (1991) (0)
GENETIC AND BIOCHEMICAL ANALYSIS OF TRANSLESION SYNTHESIS : INVOLVEMENT OF ALL THREE SOS-INDUCIBLE DNA POLYMERASES (POL II, POL IV AND POL V) IN INDUCED MUTAGENESIS. (2000) (0)
Detection of in vivo Mutations Using Transgenic Mouse (1997) (0)
Cloning of Salmonella typhimurium genes for nitroreductase and acetyltransferase, enzymes known to activate some nitroarenes (1987) (0)
[Bacterial mutagenicity tests on irradiated foods (fish-meat cake, wiener and orange juice)]. (1982) (0)
P-068 Analyses of ENU-induced germline mutation spectrum detected by mouse whole exome sequencing(Poster Sessions) (2015) (0)
" "Intellectual Network for Safe Environment Intellectual Network for Safe Environment" " ~From Molecular Biology to Regulatory Sciences From Molecular Biology to Regulatory Sciences~ ~ (2011) (0)
The general Assembly of the International Association of Environmental Mutagenesis and Genomics Societies (IAEMGS) in 2017 (2018) (0)
DNA polymerase κ suppresses inflammation and inflammation-induced mutagenesis and carcinogenic potential in the colon of mice (2023) (0)
In Vivo Mutagenesis by UVB Irradiation: Detection and the Underlying Mechanisms (2012) (0)
The use of Salmonella strains lacking classical nitroreductase or acetyltransferase activity, for the primary characterization of environmental complex mixtures (1998) (0)
T1181 Helicobacter pylori Infection Induces Gastric Mutations in Mice: Influence of Gender and Duration of Infection (2010) (0)
Preface : Genes and Environment: Voice of JEMS (2006) (0)
Possible Mechanisms of Practical Thresholds for Genotoxicity1 (2008) (0)
Molecular species of liver microsomal cytochrome P-450 from Syrian hamster and their abilities to activate phenacetin to direct-acting mutagens (1986) (0)
Detection and characterization of mitomycin C-induced gene mutations and micronuclei in the gpt delta L1 cell(Mutagenicity, Carcinogenicity, Proceedings of the 32nd Annual Meeting) (2005) (0)
Purification and interactions of the MucA’ and MucB proteins constituting the DNA polymerase RI (2019) (0)
Construction and characterization of adast deletion derivative of Salmonella typhimurium TA1535 (1992) (0)
Estimation of the frequency of inherited germline mutations by whole exome sequencing in ethyl nitrosourea-treated and untreated gpt delta mice (2016) (0)
P-071 Genotoxicity of nanoparticles in in vivo assay systems(Poster Session) (2008) (0)
The molecular basis for the erroneous incorporation of 8-oxo-dGTP by human DNA polymerase η and κ (2009) (0)
P-100 Specificity of replicative and SOS-inducible DNA polymerases in frameshift mutagenesis : Mutability of Salmonella typhimurium strains overexpressing SOS-inducible DNA polymerases to 30 chemical mutagens(Poster Presentations(2)) (2005) (0)
Molecular species of cytochrome P-450 involved in metabolic activation of phenacetin (1985) (0)
P-135(O-13) Analyses of spontaneous and induced mutations using gpt delta transgenic rodents(VII. Genotoxicity Test (II),Poster Presentation) (2012) (0)
The effect of soy isoflavone on oxidative DNA damage by Ames test (2004) (0)
Transgenic rat models for mutagenesis and carcinogenesis (2017) (0)
Genomic integration of lambda EG10 transgene in gpt delta transgenic rodents (2015) (0)
Improvement of the Spi assay for gpt delta mice by including magnesium ions during plaque formation (2002) (0)
Development of high-throughput genotoxicity assays (2005) (0)
DNA PKcs-independent error-prone DNA end-joining pathway and its role in radiation-induced mutagenesis (2002) (0)
Molecular basis of the new derivative of S.typhimurium TA100 and TA98 highly sensitive to mutagenic nitroarenes and aromatic amines: nucleotide sequences of nitroreductase and O-acetyltransferase genes (1991) (0)
A FORM OF CYTOCHROME P-450 WITH HIGH SPECIFICITY FOR AFLATOXIN B_1. ITS PURIFICATION AND SPECIES SPECIFICITY (1987) (0)
DNA polymerase kappa protects human cells against MMC-induced genotoxicity through error-free translesion DNA synthesis (2017) (0)
Contribution of cell proliferation possibly due to inactivation of protein phosphatase 2A to gene mutations induced by estragole (2015) (0)
Greetings from The International Association of Environmental Mutagenesis and Genomics Societies (2015) (0)
DNA polymerase kappa-dependent DNA synthesis at stalled replication forks is required for CHK 1 activation (2013) (0)
Development of new transgenic mice designed for detecting in vivo mutagenesis (II): positive selection and rapid DNA sequencing of mutant gpt genes (1996) (0)
P-075 An in vivo protective roles of DNA polymerase kappa against induction of DNA double strand breaks by mitomycin C : Immunohistological analysis with γ H2AX as an index(Poster Sessions) (2014) (0)
Special Issue for the 2nd Asian Conference on Environmental Mutagens (2nd ACEM): Harmonization of Genes and Environment (2011) (0)
Molecular basis of the Salmonella typhimurium tester strains possessing different nitroreductase of O-acetyltransferase activities: identification of the mutational changes of strains TA98NR and TA98/1,8-DNP6 (1991) (0)
Roles of umuDCST and samAB genes in UV and chemical mutagenesis in Salmonella typhimurium (1992) (0)
P012 In vivo mutations by 3,6-dinitrobenzo[e]pyrene instilled into the lung of gpt delta transgenic mice (2007) (0)
Cloning and characterization of the new umu-DC-like operon (samAB) of Salmonella typhimurium (1991) (0)
Time-course study of mutagenicity induced by N-ethyl-N-nitrosourea and analysis of mutational spectrum in gpt delta transgenic rat. (2002) (0)
Toxicity, genotoxicity, and carcinogenicity of 2-methylfuran in a 90-day comprehensive toxicity study in gpt delta rats. (2022) (0)
What is the Molecular Mechanism of UV Mutagenesis in Escherichia coli (1991) (0)
Biochemical characterization and spontaneous reverse mutation in alkylating-agent hypersensitive strain of S. typhimurium (1996) (0)
Possible involvement of genotoxic mechanisms in estragole-induced hepatocarcinogenesis in rats (2012) (0)
Preface (2020) (0)
Studies on in vitro packaging extracts for bacteriophage lambda DNA suitable for transgenic rodent mutagenesis assay systems (1996) (0)
Mechanism of species difference in bucetin mutagenicity: A key mechanistic role of deacylation by rat and hamster liver microsomes (1984) (0)
Cloning and nucleotide sequence of the guanine phosphoribosyl-transferase (gpt) gene of Salmonella typhimurium (1991) (0)
The application of hepatic P450 reductase null gpt delta mice in studying the role of hepatic P450 in genotoxic carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced mutagenesis (2012) (0)
Relationship between ease of reduction and mutagenicity of dinitroarenes in Salmonella typhimurium strains TA98 and TA98NR (1991) (0)
Mutagenicity of carcinogenic heterocyclic amines in Salmonella typhimurium YG strains and transgenic rodents including gpt delta (2021) (0)
Site-directed mutagenesis of the MucB mutagenesis protein : Generation, purification and analysis of MucB104 mutant. (1998) (0)
Development of new transgenic mice designed for detecting in vivo mutagenesis (I) (1996) (0)
The general Assembly of the International Association of Environmental Mutagenesis and Genomics Societies (IAEMGS) in 2017 (2018) (0)
Mutation Induction by Heavy-ion irradiation of gpt Δ Transgenic Mouse : (2000) (0)
Effects of a high fat diet on in vivo mutagenicity induced by heterocyclic amine in the livers of GPT delta rats (2014) (0)
Mutagenicity of wood smoke condensates in the Ames test (1991) (0)
Expression and Activity of Human DNA Polymerase h in Escherichia coli (2013) (0)
[The molecular mechanism of UV-induced mutagenesis in Escherichia coli]. (1991) (0)
Establishment of Salmonella Tester Strains Co-expressing Cytochrome P450 and NADPH-cytochrome P450 Reductase. (1998) (0)
Differences in the clastogenic response to heterocyclic amines and nitroarenes among Chinese hamster CHL/IU sublines transfected with human or Salmonella-derived acetyltransferase genes (1995) (0)
DNA sequence changes induced by steviol at the guanine phosphoribosyltransferase (gpt) gene on chromosome of Salmonella typhimurium TM677 (1993) (0)
Mutagenic Heterocyclic Amines Tester Strain Highly Sensitive to Salmonella Establishment of a Updated (2006) (0)
Development of new Salmonella typhimurium tester strains highly sensitive to mutagenic nitroarenes and aromatic amines (1991) (0)
The mutation spectrum induced by steviol in the coding region of the guanine phosphoribosyltransferase gene (gpt) on a chromosome of Salmonella typhimurium TM677 (1995) (0)
Characteristic mutations induced in the small intestine of Msh2-knockout gpt delta mice (2021) (0)
The role of DNA polymerase ζ in benzo[a]pyrene-induced mutagenesis in the mouse lung. (2021) (0)
Genes and Environment: Voice of JEMS (2006) (0)
In vivo mutagenicity and oxidative DNA damage in the livers of gpt delta mice treated with flumequine(Mutagenicity, Carcinogenicity, Proceedings of the 32nd Annual Meeting) (2005) (0)
Alterations in the mutagenicity and mutation spectrum induced by benzo[a]pyrene instilled in the lungs of gpt delta mice of various ages (2015) (0)
Environmental mutagen society of JapanTransfection of Salmonella typhimurium nitroreductase or O-acetyltransferase gene to Chinese hamster lung (CHL) cells in culture (1992) (0)
P XV.22 New transgenic mouse gpt-delta for the efficient detection of point mutations and deletions in vivo (1997) (0)
Transfection of O-acetyltransferase and nitroreductase genes derived from S. typhimurium to cultured chinese hamster cells (1991) (0)
Mechanism of induced mutation of phenylhydroxylamine derivatives (1985) (0)
New tester strains hypersensitive to mutagenic alkylating agents (1995) (0)
Mutation induction by heavy ion irradiation of gpt delta transgenic mice. (2000) (0)
Progress in the purification of MucA'B mutagenesis proteins (1996) (0)
A conaborative study of the mutagenicity assay using gpt delta transgenic mouse (2000) (0)
P-120 Difference in mutagenicity of structural isomers 2,4-DAT and 2,6-DAT in the target organ for carcinogenicity of F344 gpt delta transgenic rat(Poster Session) (2008) (0)
In vivo positive mutagenicity of 1,4-dioxane and quantitative analysis of its mutagenicity and carcinogenicity in rats (2018) (0)
gpt delta Transgenic Mouse Mutagenesis Test System (1998) (0)
Molecular dissection of in vivo DNA rearrangements induced by radiation and chemical mutagens (2005) (0)
Novel phage lambda Cre-lox vectors designed for development of gene mutation assays using transgenic mice (1995) (0)
Change over time of the mutagenicity in the lungs of gpt delta transgenic mice by extract of airborne particles collected from ambient air in the Tokyo metropolitan area (2018) (0)
Expression of genes of nitroreductase and O-acetyltransferase of Salmonella typhimurium in Chinese hamster lung (CHL) cells (1993) (0)
Analysis of Damaged Base Recognition by DNA Polymerases using Atomic Force Microscopy (2003) (0)
Improvement and Evaluation of High Throughput Fluctuation Ames Test Using 384-well Plate with Salmonella typhimurium TA 100 and TA 98 (2009) (0)
Mutagenicity and possible intracellular metabolic activation pathway of nitrofluorenes and nitrofluorenones (1986) (0)
Frameshift mutations induced by benzo[a]pyrene are strongly promoted by Escherichia coli DNA polymerase IV (DinB) (2000) (0)
NEW MUTAGENICITY TESTS USING HUMAN GENES ENCODING DNA REPAIR ENZYMES. (1998) (0)
The sensitivity of mutMST disrupted strains of Salmonella typhimurium against mutagens that cause oxidative DNA damage (1996) (0)
Suppression of radiation-induced large deletions by combined treatments with a tobacco-specific nitrosamine in the lung of gpt delta transgenic mice (2007) (0)
P-003 DNA polymerase kappa plays a role in in vivo translesion DNA synthesis over cisplatin adducts(Poster Sessions) (2015) (0)
Revievv Possible Mechanisms of Genotoxicityi PracticalThresholds for (2017) (0)
1,2-dimethylhydrazene plus dextran sodium sulfate-induced inflammation-associated carcinogenicity and genotoxicitiy in the colon of gpt delta rats (2011) (0)
Preferential induction of AT → TA transversions by chlorambucil at the hisG428 site of Salmonella typhimurium TA102 (1991) (0)
My career development with Ames test: A personal recollection. (2019) (0)

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