Takeshi Sakurai
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Computer Science
Takeshi Sakurai's Degrees
- PhD Computer Science University of Tokyo
- Masters Computer Science University of Tokyo
- Bachelors Computer Science University of Tokyo
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(Suggest an Edit or Addition)Takeshi Sakurai's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Orexins and Orexin Receptors: A Family of Hypothalamic Neuropeptides and G Protein-Coupled Receptors that Regulate Feeding Behavior (1998) (5007)
- Cloning of a cDNA encoding a non-isopeptide-selective subtype of the endothelin receptor (1990) (2427)
- Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior. (1998) (2157)
- Genetic Ablation of Orexin Neurons in Mice Results in Narcolepsy, Hypophagia, and Obesity (2001) (1375)
- Autism genome-wide copy number variation reveals ubiquitin and neuronal genes (2009) (1364)
- The neural circuit of orexin (hypocretin): maintaining sleep and wakefulness (2007) (1106)
- Orexins, orexigenic hypothalamic peptides, interact with autonomic, neuroendocrine and neuroregulatory systems. (1999) (1018)
- Common genetic variants on 5p14.1 associate with autism spectrum disorders (2009) (970)
- Hypothalamic Orexin Neurons Regulate Arousal According to Energy Balance in Mice (2003) (870)
- Distribution of orexin neurons in the adult rat brain 1 Published on the World Wide Web on 17 March 1999. 1 (1999) (704)
- Haploinsufficiency of the autism-associated Shank3 gene leads to deficits in synaptic function, social interaction, and social communication (2010) (507)
- Ghrelin-induced food intake is mediated via the orexin pathway. (2003) (469)
- Hypocretin/Orexin Excites Hypocretin Neurons via a Local Glutamate Neuron—A Potential Mechanism for Orchestrating the Hypothalamic Arousal System (2002) (451)
- Orexin/Hypocretin: A Neuropeptide at the Interface of Sleep, Energy Homeostasis, and Reward System (2009) (423)
- Interaction between the Corticotropin-Releasing Factor System and Hypocretins (Orexins): A Novel Circuit Mediating Stress Response (2004) (408)
- Orexin (Hypocretin) Neurons Contain Dynorphin (2001) (400)
- Behavioral State Instability in Orexin Knock-Out Mice (2004) (368)
- Des-acyl ghrelin induces food intake by a mechanism independent of the growth hormone secretagogue receptor. (2006) (362)
- Orexin-induced hyperlocomotion and stereotypy are mediated by the dopaminergic system 1 1 Published on the World Wide Web on 27 June 2000. (2000) (351)
- Ephrin-B2 and EphB1 Mediate Retinal Axon Divergence at the Optic Chiasm (2003) (344)
- Genome-wide copy number variation study associates metabotropic glutamate receptor gene networks with attention deficit hyperactivity disorder (2011) (337)
- Orexin peptides prevent cataplexy and improve wakefulness in an orexin neuron-ablated model of narcolepsy in mice. (2004) (321)
- Orexins activate histaminergic neurons via the orexin 2 receptor. (2002) (286)
- Neurons containing orexin in the lateral hypothalamic area of the adult rat brain are activated by insulin-induced acute hypoglycemia (1999) (278)
- The emerging role of synaptic cell-adhesion pathways in the pathogenesis of autism spectrum disorders (2009) (275)
- Orexin-induced food intake involves neuropeptide Y pathway (2000) (267)
- Input of Orexin/Hypocretin Neurons Revealed by a Genetically Encoded Tracer in Mice (2005) (264)
- Orexin neuronal circuitry: Role in the regulation of sleep and wakefulness (2008) (263)
- Roles of orexin/hypocretin in regulation of sleep/wakefulness and energy homeostasis. (2005) (263)
- Enhanced orexin receptor-2 signaling prevents diet-induced obesity and improves leptin sensitivity. (2009) (258)
- Orexins (hypocretins) directly interact with neuropeptide Y, POMC and glucose‐responsive neurons to regulate Ca2+ signaling in a reciprocal manner to leptin: orexigenic neuronal pathways in the mediobasal hypothalamus (2004) (251)
- Linking oligodendrocyte and myelin dysfunction to neurocircuitry abnormalities in schizophrenia (2011) (245)
- Narcolepsy — clinical spectrum, aetiopathophysiology, diagnosis and treatment (2019) (239)
- Input of Orexin/Hypocretin Neurons Revealed by a Genetically Encoded Tracer in Mice (2005) (234)
- Pharmacogenetic Modulation of Orexin Neurons Alters Sleep/Wakefulness States in Mice (2011) (229)
- Chronic intracerebroventricular administration of orexin-A to rats increases food intake in daytime, but has no effect on body weight (1999) (219)
- Differential roles of orexin receptor-1 and -2 in the regulation of non-REM and REM sleep (2011) (215)
- Orexin Neurons Function in an Efferent Pathway of a Food-Entrainable Circadian Oscillator in Eliciting Food-Anticipatory Activity and Wakefulness (2004) (206)
- Orexins and orexin receptors: implication in feeding behavior (1999) (204)
- Role of orexin in modulating arousal, feeding, and motivation (2013) (203)
- Structure and Function of Human Prepro-orexin Gene* (1999) (201)
- Regulation of orexin neurons by the monoaminergic and cholinergic systems. (2003) (201)
- Connectomics of orexin-producing neurons: interface of systems of emotion, energy homeostasis and arousal. (2011) (200)
- Serotonergic Regulation of the Orexin/Hypocretin Neurons through the 5-HT1A Receptor (2004) (195)
- The role of orexin in motivated behaviours (2014) (194)
- Reduced food anticipatory activity in genetically orexin (hypocretin) neuron‐ablated mice (2004) (188)
- Difference in obesity phenotype between orexin-knockout mice and orexin neuron-deficient mice with same genetic background and environmental conditions (2005) (187)
- Cellular Clocks in AVP Neurons of the SCN Are Critical for Interneuronal Coupling Regulating Circadian Behavior Rhythm (2015) (186)
- Activity-Induced Protocadherin Arcadlin Regulates Dendritic Spine Number by Triggering N-Cadherin Endocytosis via TAO2β and p38 MAP Kinases (2007) (180)
- Orexins/hypocretins regulate drinking behaviour 1 Published on the World Wide Web on 4 August 1999. 1 (1999) (177)
- Expression of a Poly-Glutamine-Ataxin-3 Transgene in Orexin Neurons Induces Narcolepsy–Cataplexy in the Rat (2004) (177)
- The orexin system: roles in sleep/wake regulation (2010) (175)
- Characterization of a family of endogenous neuropeptide ligands for the G protein-coupled receptors GPR7 and GPR8 (2003) (175)
- The role of orexin in motivated behaviours (2014) (169)
- Identification of a population of sleep-active cerebral cortex neurons (2008) (165)
- Conditional Ablation of Orexin/Hypocretin Neurons: A New Mouse Model for the Study of Narcolepsy and Orexin System Function (2014) (162)
- A neuropeptide ligand of the G protein-coupled receptor GPR103 regulates feeding, behavioral arousal, and blood pressure in mice. (2006) (158)
- Orexin receptor type-1 couples exclusively to pertussis toxin-insensitive G-proteins, while orexin receptor type-2 couples to both pertussis toxin-sensitive and -insensitive G-proteins. (2003) (158)
- Coreleased Orexin and Glutamate Evoke Nonredundant Spike Outputs and Computations in Histamine Neurons (2014) (153)
- USAG-1: a bone morphogenetic protein antagonist abundantly expressed in the kidney. (2004) (146)
- Uterine sensitization-associated gene-1 (USAG-1), a novel BMP antagonist expressed in the kidney, accelerates tubular injury. (2005) (140)
- Selective loss of GABAB receptors in orexin-producing neurons results in disrupted sleep/wakefulness architecture (2009) (130)
- Orexin neurons are directly and indirectly regulated by catecholamines in a complex manner. (2006) (124)
- Age-related insulin resistance in hypothalamus and peripheral tissues of orexin knockout mice (2008) (123)
- Optogenetic Probing of Fast Glutamatergic Transmission from Hypocretin/Orexin to Histamine Neurons In Situ (2012) (123)
- Roles of orexins in regulation of feeding and wakefulness (2002) (119)
- Hypocretin/Orexin Neurons Contribute to Hippocampus-Dependent Social Memory and Synaptic Plasticity in Mice (2013) (117)
- Orexin neurons suppress narcolepsy via 2 distinct efferent pathways. (2014) (117)
- Cholecystokinin Activates Orexin/Hypocretin Neurons through the Cholecystokinin A Receptor (2005) (111)
- Optic Chiasm Presentation of Semaphorin6D in the Context of Plexin-A1 and Nr-CAM Promotes Retinal Axon Midline Crossing (2012) (110)
- Haploinsufficiency of Gtf2i, a gene deleted in Williams Syndrome, leads to increases in social interactions (2011) (109)
- A discrete neuronal circuit induces a hibernation-like state in rodents (2020) (108)
- GABAB receptor‐mediated modulation of hypocretin/orexin neurones in mouse hypothalamus (2006) (103)
- Ankyrin binding mediates L1CAM interactions with static components of the cytoskeleton and inhibits retrograde movement of L1CAM on the cell surface (2003) (101)
- Orexin neurons are indispensable for stress‐induced thermogenesis in mice (2010) (100)
- Sleep/wake fragmentation disrupts metabolism in a mouse model of narcolepsy (2007) (100)
- Orexin neuron-mediated skeletal muscle vasodilation and shift of baroreflex during defense response in mice. (2006) (100)
- Structure, tissue distribution, and pharmacological characterization of Xenopus orexins (1999) (99)
- The role of NrCAM in neural development and disorders—Beyond a simple glue in the brain (2012) (98)
- Orexin Receptor-1 in the Locus Coeruleus Plays an Important Role in Cue-Dependent Fear Memory Consolidation (2013) (96)
- Orexin: a link between energy homeostasis and adaptive behaviour. (2003) (94)
- Haploinsufficiency of Cyfip1 Produces Fragile X-Like Phenotypes in Mice (2012) (92)
- Roles of orexins and orexin receptors in central regulation of feeding behavior and energy homeostasis. (2006) (91)
- Immunohistochemical characterization of localization of long-form leptin receptor (OB-Rb) in neurochemically defined cells in the ovine hypothalamus (2001) (90)
- Nonpeptide orexin type-2 receptor agonist ameliorates narcolepsy-cataplexy symptoms in mouse models (2017) (89)
- Hypocretin/orexin and nociceptin/orphanin FQ coordinately regulate analgesia in a mouse model of stress-induced analgesia. (2008) (89)
- Orchestrated ensemble activities constitute a hippocampal memory engram (2019) (87)
- A Role for Nr-CAM in the Patterning of Binocular Visual Pathways (2006) (86)
- Orexin (Hypocretin) Receptor Agonists and Antagonists for Treatment of Sleep Disorders (2013) (84)
- NrCAM in Addiction Vulnerability: Positional Cloning, Drug-Regulation, Haplotype-Specific Expression, and Altered Drug Reward in Knockout Mice (2006) (82)
- IGFBP3 Colocalizes with and Regulates Hypocretin (Orexin) (2009) (81)
- Elevated body temperature during sleep in orexin knockout mice. (2006) (81)
- Thyrotropin-Releasing Hormone Increases Behavioral Arousal through Modulation of Hypocretin/Orexin Neurons (2009) (75)
- Loss of the BMP antagonist USAG-1 ameliorates disease in a mouse model of the progressive hereditary kidney disease Alport syndrome. (2010) (75)
- Orexin neurons in the hypothalamus mediate cardiorespiratory responses induced by disinhibition of the amygdala and bed nucleus of the stria terminalis (2009) (73)
- Orexin Gene Transfer into Zona Incerta Neurons Suppresses Muscle Paralysis in Narcoleptic Mice (2011) (72)
- Serotonin neurons in the dorsal raphe mediate the anticataplectic action of orexin neurons by reducing amygdala activity (2017) (72)
- GABAergic neurons in the preoptic area send direct inhibitory projections to orexin neurons (2013) (72)
- Linking White and Grey Matter in Schizophrenia: Oligodendrocyte and Neuron Pathology in the Prefrontal Cortex (2009) (72)
- Lowering glucose concentrations increases cytosolic Ca2+ in orexin neurons of the rat lateral hypothalamus (2001) (70)
- Orexin modulates behavioral fear expression through the locus coeruleus (2017) (69)
- Rudiment incisors survive and erupt as supernumerary teeth as a result of USAG-1 abrogation. (2007) (68)
- Neurotensin Co-Expressed in Orexin-Producing Neurons in the Lateral Hypothalamus Plays an Important Role in Regulation of Sleep/Wakefulness States (2013) (68)
- Orexins and orexin receptors: from molecules to integrative physiology. (2008) (67)
- Enhanced BMP signaling results in supernumerary tooth formation in USAG-1 deficient mouse. (2008) (67)
- Mitigation of Murine Focal Cerebral Ischemia by the Hypocretin/Orexin System is Associated With Reduced Inflammation (2013) (66)
- MAP kinase pathway-dependent phosphorylation of the L1-CAM ankyrin binding site regulates neuronal growth. (2006) (66)
- Aromatic D-amino acids act as chemoattractant factors for human leukocytes through a G protein-coupled receptor, GPR109B (2009) (65)
- Orexin (hypocretin) gene transfer diminishes narcoleptic sleep behavior in mice (2008) (65)
- Converging models of schizophrenia – Network alterations of prefrontal cortex underlying cognitive impairments (2015) (64)
- Activation of orexin neurones after noxious but not conditioned fear stimuli in rats (2002) (64)
- Comprehensive Behavioral Analysis of Male Ox1r−/− Mice Showed Implication of Orexin Receptor-1 in Mood, Anxiety, and Social Behavior (2015) (63)
- Sparse Activity of Hippocampal Adult-Born Neurons during REM Sleep Is Necessary for Memory Consolidation (2020) (63)
- Vasopressin Increases Locomotion through a V1a Receptor in Orexin/Hypocretin Neurons: Implications for Water Homeostasis (2008) (63)
- Expression of BMP-7 and USAG-1 (a BMP antagonist) in kidney development and injury. (2008) (61)
- Roles of glial cells in schizophrenia: Possible targets for therapeutic approaches (2013) (60)
- Association analysis of the NrCAM gene in autism and in subsets of families with severe obsessive–compulsive or self-stimulatory behaviors (2006) (59)
- Hypothalamic Orexin Prevents Hepatic Insulin Resistance via Daily Bidirectional Regulation of Autonomic Nervous System in Mice (2014) (59)
- Manipulating the Cellular Circadian Period of Arginine Vasopressin Neurons Alters the Behavioral Circadian Period (2016) (58)
- OX1 and OX2 orexin/hypocretin receptor pharmacogenetics (2014) (57)
- Histamine‐1 receptor is not required as a downstream effector of orexin‐2 receptor in maintenance of basal sleep/wake states (2010) (55)
- Orexin deficiency and narcolepsy (2013) (53)
- Reverse pharmacology of orexin: from an orphan GPCR to integrative physiology (2005) (53)
- Deficiency of p62/Sequestosome 1 Causes Hyperphagia Due to Leptin Resistance in the Brain (2013) (52)
- Bmal1 in the Nervous System Is Essential for Normal Adaptation of Circadian Locomotor Activity and Food Intake to Periodic Feeding (2011) (51)
- Effects of a newly developed potent orexin-2 receptor-selective antagonist, compound 1 m, on sleep/wakefulness states in mice (2014) (50)
- Slc25a12 Disruption Alters Myelination and Neurofilaments: A Model for a Hypomyelination Syndrome and Childhood Neurodevelopmental Disorders (2010) (50)
- Involvement of the serotonergic system in orexin-induced behavioral alterations in rats (2002) (49)
- Orexin-mediated feeding behavior involves both leptin-sensitive and -insensitive pathways (2002) (48)
- Sex difference in body weight gain and leptin signaling in hypocretin/orexin deficient mouse models (2006) (48)
- Variants of the orexin2/hcrt2 receptor gene identified in patients with excessive daytime sleepiness and patients with Tourette's syndrome comorbidity (2004) (48)
- Effects of orexin on cultured porcine adrenal medullary and cortex cells (2002) (47)
- Orexin and Orexin Receptors (2005) (47)
- Orexins suppress catecholamine synthesis and secretion in cultured PC12 cells. (2000) (46)
- Overview of orexin/hypocretin system. (2012) (46)
- Regulation of orexin neurons by the monoaminergic and cholinergic systems (2004) (45)
- Large-scale forward genetics screening identifies Trpa1 as a chemosensor for predator odor-evoked innate fear behaviors (2018) (44)
- Evolution of Orexin Neuropeptide System: Structure and Function (2020) (43)
- The orexin/hypocretin system : physiology and pathophysiology (2006) (43)
- Ectopic Overexpression of Orexin Alters Sleep/Wakefulness States and Muscle Tone Regulation during REM Sleep in Mice (2011) (43)
- Distribution of neuropeptide W immunoreactivity and mRNA in adult rat brain (2006) (41)
- Hypocretin receptor expression in canine and murine narcolepsy models and in hypocretin-ligand deficient human narcolepsy. (2008) (40)
- Cholinergic regulation of orexin/hypocretin neurons through M(3) muscarinic receptor in mice. (2008) (39)
- Association of An Orexin 1 Receptor 408Val Variant with Polydipsia–Hyponatremia in Schizophrenic Subjects (2005) (38)
- Increased expression of receptor phosphotyrosine phosphatase-β/ζ is associated with molecular, cellular, behavioral and cognitive schizophrenia phenotypes (2011) (38)
- Monoamines Inhibit GABAergic Neurons in Ventrolateral Preoptic Area That Make Direct Synaptic Connections to Hypothalamic Arousal Neurons (2018) (38)
- Orexin neurons are indispensable for prostaglandin E2‐induced fever and defence against environmental cooling in mice (2013) (37)
- Integrative physiology of orexins and orexin receptors. (2009) (37)
- Sleep and Wakefulness Are Controlled by Ventral Medial Midbrain/Pons GABAergic Neurons in Mice (2018) (37)
- Differential Roles of Orexin Receptors in the Regulation of Sleep/Wakefulness (2013) (37)
- Excitation of GABAergic Neurons in the Bed Nucleus of the Stria Terminalis Triggers Immediate Transition from Non-Rapid Eye Movement Sleep to Wakefulness in Mice (2017) (37)
- The Human Prepro-orexin Gene Regulatory Region That Activates Gene Expression in the Lateral Region and Represses It in the Medial Regions of the Hypothalamus* (2002) (36)
- The NPB/NPW neuropeptide system and its role in regulating energy homeostasis, pain, and emotion. (2008) (34)
- Decreased Intake of Sucrose Solutions in Orexin Knockout Mice (2011) (33)
- Roles of orexins in the regulation of body weight homeostasis. (2014) (33)
- Neuron-related blood inflammatory markers as an objective evaluation tool for major depressive disorder: An exploratory pilot case-control study. (2018) (33)
- Dexmedetomidine inhibits muscarinic type 3 receptors expressed in Xenopus oocytes and muscarine-induced intracellular Ca2+ elevation in cultured rat dorsal root ganglia cells (2007) (32)
- Roles of orexins in the regulation of feeding and arousal. (2002) (32)
- The juxtaparanodal proteins CNTNAP2 and TAG1 regulate diet-induced obesity (2012) (31)
- NPBWR1 and NPBWR2: Implications in Energy Homeostasis, Pain, and Emotion (2012) (31)
- Hypocretin/orexin deficiency decreases cocaine abuse liability (2018) (31)
- Odour-induced analgesia mediated by hypothalamic orexin neurons in mice (2016) (30)
- Identification of N-arachidonylglycine, U18666A, and 4-androstene-3,17-dione as novel insulin Secretagogues. (2005) (30)
- Critical Role of Neuropeptides B/W Receptor 1 Signaling in Social Behavior and Fear Memory (2011) (30)
- Ulk2 controls cortical excitatory–inhibitory balance via autophagic regulation of p62 and GABAA receptor trafficking in pyramidal neurons (2018) (30)
- Orexin-neuromodulated cerebellar circuit controls redistribution of arterial blood flows for defense behavior in rabbits (2013) (29)
- Orexin as a modulator of fear-related behavior: Hypothalamic control of noradrenaline circuit (2020) (29)
- A mouse model of 22q11.2 deletions: Molecular and behavioral signatures of Parkinson’s disease and schizophrenia (2018) (29)
- The role of cell adhesion molecules in brain wiring and neuropsychiatric disorders (2017) (29)
- Orexin Receptor Multimerization versus Functional Interactions: Neuropharmacological Implications for Opioid and Cannabinoid Signalling and Pharmacogenetics (2017) (29)
- Orexin Neurons Receive Glycinergic Innervations (2011) (28)
- Rapid eye movement sleep is initiated by basolateral amygdala dopamine signaling in mice (2022) (28)
- Sleep Control, GPCRs, and Glucose Metabolism (2016) (27)
- New Developments in Sleep Research: Molecular Genetics, Gene Expression, and Systems Neurobiology (2008) (27)
- QRFP-Deficient Mice Are Hypophagic, Lean, Hypoactive and Exhibit Increased Anxiety-Like Behavior (2016) (27)
- A large‐scale screen for coding variants in SERT/SLC6A4 in autism spectrum disorders (2008) (27)
- Cognitive functions associated with developing prefrontal cortex during adolescence and developmental neuropsychiatric disorders (2019) (26)
- Loss of Function Studies in Mice and Genetic Association Link Receptor Protein Tyrosine Phosphatase α to Schizophrenia (2011) (25)
- Associations between the orexin (hypocretin) receptor 2 gene polymorphism Val308Ile and nicotine dependence in genome-wide and subsequent association studies (2015) (24)
- Memory consolidation during sleep and adult hippocampal neurogenesis (2019) (23)
- Glutamatergic neurons in the medial prefrontal cortex mediate the formation and retrieval of cocaine‐associated memories in mice (2020) (23)
- Timed Inhibition of Orexin System by Suvorexant Improved Sleep and Glucose Metabolism in Type 2 Diabetic db/db Mice. (2016) (23)
- Role of DISC1 in Neuronal Trafficking and its Implication in Neuropsychiatric Manifestation and Neurotherapeutics (2017) (23)
- NrCAM‐regulating neural systems and addiction‐related behaviors (2014) (23)
- Behavioral state instability in orexin knockout mice (2004) (22)
- Attenuated phrenic long-term facilitation in orexin neuron-ablated mice (2009) (21)
- Characterization of sleep–wake patterns in a novel transgenic mouse line overexpressing human prepro‐orexin/hypocretin (2010) (21)
- A Single Nucleotide Polymorphism of the Neuropeptide B/W Receptor-1 Gene Influences the Evaluation of Facial Expressions (2012) (19)
- Introduction of the human AVPR1A gene substantially alters brain receptor expression patterns and enhances aspects of social behavior in transgenic mice (2014) (19)
- Serotonergic Input to Orexin Neurons Plays a Role in Maintaining Wakefulness and REM Sleep Architecture (2018) (19)
- Characterizing vulnerable brain areas and circuits in mouse models of autism: Towards understanding pathogenesis and new therapeutic approaches (2020) (18)
- Concise Review: Regulatory Influence of Sleep and Epigenetics on Adult Hippocampal Neurogenesis and Cognitive and Emotional Function (2018) (18)
- Activation of Bombesin Receptor Subtype-3 Influences Activity of Orexin Neurons by Both Direct and Indirect Pathways (2010) (17)
- Sequence of Molecular Events during the Maturation of the Developing Mouse Prefrontal Cortex (2015) (15)
- Chronic Alterations in Monoaminergic Cells in the Locus Coeruleus in Orexin Neuron-Ablated Narcoleptic Mice (2013) (15)
- Nighttime Administration of Nicotine Improves Hepatic Glucose Metabolism via the Hypothalamic Orexin System in Mice. (2016) (14)
- Activation of lateral hypothalamic group III metabotropic glutamate receptors suppresses cocaine-seeking following abstinence and normalizes drug-associated increases in excitatory drive to orexin/hypocretin cells (2019) (14)
- A Discrete Glycinergic Neuronal Population in the Ventromedial Medulla That Induces Muscle Atonia during REM Sleep and Cataplexy in Mice (2020) (14)
- [Regulatory mechanism of sleep/wakefulness states by orexin]. (2007) (12)
- Anticoagulant factor protein S inhibits the proliferation of rat astrocytes after injury (1996) (12)
- Effects of Anesthetics on the Function of Orexin-1 Receptors Expressed in Xenopus Oocytes (2007) (11)
- Effect of context exposure after fear learning on memory generalization in mice (2016) (10)
- Evolutionary Origin of Distinct NREM and REM Sleep (2020) (10)
- Mesolimbic neuropeptide W coordinates stress responses under novel environments (2016) (10)
- The Orexin/Hypocretin System (2005) (9)
- [Circadian rhythm of leptin, orexin and ghrelin]. (2012) (9)
- Fine-Tuning Circadian Rhythms: The Importance of Bmal1 Expression in the Ventral Forebrain (2017) (9)
- Effect of neuropeptide B on feeding behavior is influenced by endogenous corticotropin-releasing factor activities (2008) (9)
- Methylphenidate and Guanfacine Ameliorate ADHD-Like Phenotypes in Fez1-Deficient Mice (2018) (9)
- Running title : Orexin ( Hypocretin ) Receptor Agonists and Antagonists for Treatment of Sleep Disorders Orexin ( Hypocretin ) Receptor Agonists and Antagonists for Treatment of Sleep Disorders Rationale for Development and Current Status (2017) (9)
- Circadian characteristics of mice depleted with GPR7. (2009) (9)
- Auditory conditioned stimulus presentation during NREM sleep impairs fear memory in mice (2017) (8)
- [Roles of biologically active peptide in regulation of feeding behavior and energy homeostasis]. (2003) (7)
- Interaction between sleep mechanisms and orexin neurons (2011) (6)
- Ulk1 protects against ethanol-induced neuronal stress and cognition-related behavioral deficits (2017) (6)
- Miniaturized microscope with flexible light source input for neuronal imaging and manipulation in freely behaving animals. (2019) (6)
- Erratum: Input of orexin/hypocretin neurons revealed by a genetically encoded tracer in mice (Neuron (April 21, 2005) 46 (297-308) PII: S0896-6273(05)00205-9 and DOI: 10.1016/j.neuron.2005.03.010) (2005) (6)
- Neuronal cell adhesion molecule regulating neural systems underlying addiction (2018) (5)
- Interaction between the corticotropin-releasing-factor system and hypocretins: Components mediating the stress response (2004) (5)
- Orexin (Hypocretin) and Narcolepsy (2016) (5)
- Orexin and Sleep (2015) (5)
- Interaction between Orexin Neurons and Monoaminergic Systems. (2021) (5)
- The scaffold protein JLP plays a key role in regulating ultraviolet B‐induced apoptosis in mice (2014) (4)
- Selective loss of GABAB receptors in orexin/hypocretin-producing neurons results in disrupted sleep/wakefulness architecture (2007) (4)
- [Roles of orexin and effects of orexin receptor antagonists]. (2015) (4)
- Rescue of Narcoleptic Orexin Neuron-Ablated Mice by Ectopic Overexpression of Orexin Peptides (2006) (4)
- Activation of lateral hypothalamic group III mGluRs suppresses drug-seeking following abstinence and cocaine-associated increases in excitatory drive to orexin/hypocretin cells (2018) (3)
- Hypocretin/orexin prevents recovery from sickness. (2015) (3)
- [Hypothalamic neuropeptides implicated in the regulation of sleep/wakefulness states]. (2012) (3)
- Discovery of novel orexin receptor antagonists using a 1,3,5-trioxazatriquinane bearing multiple effective residues (TriMER) library. (2021) (3)
- Involvement of orexin in lipid accumulation in the liver (2018) (3)
- Optogenetic Manipulation of Neural Circuits During Monitoring Sleep/wakefulness States in Mice. (2019) (2)
- Roles of Orexin in Regulation of Energy Homeostasis (2003) (2)
- Rodent Models of Human Narcolepsy-cataplexy (2005) (2)
- History of Orexin Research (2015) (2)
- Schizophrenia research in 2013: Are we making progress? (2013) (2)
- History and Overview of Orexin/Hypocretin Research (2006) (1)
- Bmal1 in the nervous system is indispensable for normal adaptation of circadian locomotor activity and food intake to periodic feeding (2011) (1)
- [Neural circuitry and brain functions.] (2018) (1)
- Enhanced Orexin Neuropeptide Signaling Prevents Features of Metabolic Syndrome in Mice: 967 (2009) (1)
- [Discovery of orexin]. (2007) (1)
- Sparse activity of hippocampal adult-born neurons during REM sleep is necessary for memory consolidation. Kumar et al. -2 (2020) (1)
- Sleep Architecture in Mice Is Shaped by the Transcription Factor AP-2β (2020) (1)
- Circuitry-Based Human Neuroanatomy for the Next Generation in Psychiatry and Neuroscience (2017) (1)
- Caspase-4 as a key factor in Alzheimer pathology (2009) (1)
- LOCATION, LOCATION, LOCATION: Location of neuroinflammation is important in pathogenesis of schizophrenia (2020) (1)
- The role of interaction between orexin receptors and β2 adrenergic receptors in basolateral amygdala in dentate gyrus synaptic plasticity in male rats (2021) (1)
- [Connectomics of orexin-producing neurons: analysis using mouse models]. (2011) (1)
- Activity of Orexin-producing neurons is regulated by Neurotensin (2009) (0)
- Possible contribution of orexin-containing neurons to stress-induced thermogenesis (2009) (0)
- Effects of a newly developed orexin-2 receptor-selective antagonist on the sleep/wake states in mice (2013) (0)
- Gabaergic transmission by POA neurons to orexin neurons (2013) (0)
- Orexin neurons contribute to prostaglandin E2-induced fever (2010) (0)
- [2-molecular neurobiology of orexins]. (2000) (0)
- and supplementation studies in mice evidence from genetic and pharmacological disruption Contribution of orexin in hypercapnic chemoreflex (2015) (0)
- hypocretin‐ataxin‐3 transgenic mice, whose hypocretin neurons were postnatally ablated. Sleep‐wake activity was determined following the administration of LPS at Zeitgeber time (ZT) 8.0 in ataxin‐3 transgenic mice, and the age‐, gender‐matched wild‐type littermates. LPS injection induced increases i (2015) (0)
- A role of the NPW/NPB system in regulation of emotional responses (2007) (0)
- Animal Models of Narcolepsy (2015) (0)
- Orexin neurons mediate stress-induced hyperthermia (2010) (0)
- Effects of ablation of orexin neuron on the defense response (2005) (0)
- Physiological Roles of Orexin Receptors on Sleep/Wakefulness Regulation (2015) (0)
- Symposia Abstracts (2005) (0)
- Editorial: The Gating and Maintenance of Sleep and Wake: New Circuits and Insights (2020) (0)
- Elucidation of the physiological role of novel neuropeptides (2019) (0)
- pathways stimulates breathing via medullary and spinal (2006) (0)
- Sparse activity of hippocampal adult-born neurons during REM sleep is necessary for memory consolidation. Kumar et al. -1 (2020) (0)
- Classification : Medical Science Aromatic D-amino acids act as chemoattractant factors for human leukocytes through the G protein-coupled receptor GPR 109 B ( orphan GPCR / amino acid / leukocyte / chemoattractant / ) (2017) (0)
- A discrete neuronal circuit in central amygdala that modulates social distance and behavior (2022) (0)
- Glycinergic regulation of orexin neurons (2011) (0)
- Editorial: The Role of Neuropeptides in Sleep/Wakefulness States and the Circadian Clock (2022) (0)
- Alterations in monoaminergic neurons in orexin neuron-ablated mice (2009) (0)
- The role of NPBWR1 on autonomic nervous system (2013) (0)
- 2 Orexin and Orexin Receptors (2018) (0)
- Contents Vol. 79, 2007 (2007) (0)
- Orexins regulate drinking behavior in rats (1999) (0)
- Inhibition of orexin-induced wakefulness by pyrilamine, an H1 receptor antagonist (2004) (0)
- Orexins : Neuropeptides that regulate feeding bahavior. (2000) (0)
- [Neural Circuits Involved in Torpor and Hibernation and Prospects for Artificial Hibernation Technology]. (2022) (0)
- Molecular and cellular neuroscience special issue (2017) (0)
- Deciphering a novel neural circuit in the central amygdala implicated in regulation of social behavior (2019) (0)
- OREXIN HAS A STIMULATORY ACTION ON FEEDING BEHAVIOR IN THE GOLDFISH (2001) (0)
- Pharmacogenetic Dissection of Neural Mechanisms Underlying the Regulation of Sleep–Wakefulness Using DREADDs (2015) (0)
- Selective loss of GABAB receptors in orexin-producing neurons results in disrupted sleep/wakefulness architecture (Proceedings of the National Academy of Sciences of the United States of America (2009) 106, 11, (4459-4464) DOI: 10.1073/pnas.0811126106) (2009) (0)
- Science Journals — AAAS (2016) (0)
- [Drug development targeting synaptic molecules - autism mouse models as an example]. (2013) (0)
- Title Orexin neurons receive glycinergic innervations . Author ( s ) (2017) (0)
- OrexinReceptor-1intheLocusCoeruleusPlaysan ImportantRoleinCue-DependentFearMemory Consolidation (2013) (0)
- [Central regulation of feeding behavior]. (2015) (0)
- 2P233 Functional connection between GABAergic neurons in the preoptic area and orexinergic neurons in the hypothalamus(16. Neuronal Circuit & Information processing,Poster) (2013) (0)
- Editorial for “What can clinical findings tell us about the neurobiology of schizophrenia? Revisited” (2019) (0)
- Expression of the poly-glutamine-ataxin-3 transgene causes loss of orexin expression: A rat model of narcolepsy (2004) (0)
- Afferent Control of the Hypocretin/Orexin Neurons (2011) (0)
- Prefrontal cortex-specific p62 accumulation and subcortical abnormalities in 22q11.2 deletion syndrome model mice. (2015) (0)
- Orexin System and Feeding Behavior (2006) (0)
- Subject Index Vol. 79, 2007 (2007) (0)
- Alterations in noradrenergic neurons in orexin neuron-deficient mice (2011) (0)
- Editorial Board (2009) (0)
- [Orphan receptors: a fruitful resource for drug discovery]. (2000) (0)
- S15.3 Orexinergic modulation of the autonomic activity during emotional stress (2009) (0)
- Functional and histological interaction between preoptic area GABAergic neurons and orexin neurons (2011) (0)
- Restoration of orexin signaling in the dorsal raphe and locus coeruleus differntially ameliorate symptoms of narcoleptic mice (2013) (0)
- 2P230 ヨーロッパモノアラガイの中枢神経系における神経活動の膜 電位イメージング (II) Fluorescent Voltage Imaging of the Neural Activity in the Central Nervous System of the Pond Snail (II) (2014) (0)
- Dissection of SLITRK1 signalling in neuronal development (2006) (0)
- Erratum: Graupner et al., “Natural Firing Patterns Imply Low Sensitivity of Synaptic Plasticity to Spike Timing Compared with Firing Rate” (2019) (0)
- Function of adult-born neurons in maturation of fear memory engram during sleep (2019) (0)
- QRFP plays a critical role in regulating feeding behavior as a molecular link between the arcuate nucleus and nucleus accumbens (2011) (0)
- Chapter V Orexin receptors (2002) (0)
- Reverse pharmaclogy of orexins (1999) (0)
- Autism genetics and mouse models (2009) (0)
- Title Orexin deficiency and narcolepsy (2017) (0)
- LOCALIZATION OF OREXIN-LIKE IMMUNOREACTIVITY IN THE BRAIN OF FIVE SPECIES OF TELEOST FISH(Endocrinology)Proceedings of the Seventy-First Annual Meeting of the Zoological Society of Japan (2000) (0)
- Role of hypothalamic orexin neurons in the regulation of arousal according to energy balance (2004) (0)
- PS05.2 Neural circuit of orexin neurons: a mechanism that maintains proper sleep/wakefulness states according to inner and outer environments of animals (2007) (0)
- Orexin agonist improves inflammation-induced immobility (2018) (0)
- The Genetic Basis of Sleep and Sleep Disorders: Orexin (hypocretin) and narcolepsy (2013) (0)
- Afferent pathways to the orexinergic neurons that involved in the defense response against stressor (2007) (0)
- Sleep Architecture in Mice Is Shaped by the Transcription Factor AP-2β. (2020) (0)
- Orexinergic neurons mediate excitatory signals to Purkinje cells in a descrete microzone of the cerebellum (2007) (0)
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What Schools Are Affiliated With Takeshi Sakurai?
Takeshi Sakurai is affiliated with the following schools:
