Takeshi Tabira

Takeshi Tabira's AcademicInfluence.com Rankings

Takeshi Tabira

Biology

#12469

World Rank

#15946

Historical Rank

Neuroscience

#2095

World Rank

#2153

Historical Rank

biology Degrees

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Biology

Takeshi Tabira's Degrees

PhD Neuroscience University of Tokyo
Doctorate Medicine University of Tokyo

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Takeshi Tabira's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Neuroblastoma × spinal cord (NSC) hybrid cell lines resemble developing motor neurons (1992) (680)
Chronic Stress Induces Impairment of Spatial Working Memory Because of Prefrontal Dopaminergic Dysfunction (2000) (475)
Functional erythropoietin receptor of the cells with neural characteristics. Comparison with receptor properties of erythroid cells. (1993) (438)
Potentially amyloidogenic, carboxyl-terminal derivatives of the amyloid protein precursor. (1992) (398)
Regulation of Experimental Autoimmune Encephalomyelitis by Natural Killer (NK) Cells (1997) (383)
Transgenic mice with Alzheimer presenilin 1 mutations show accelerated neurodegeneration without amyloid plaque formation (1999) (373)
Chronic stress attenuates glucocorticoid negative feedback: involvement of the prefrontal cortex and hippocampus (2003) (339)
Trophic effect of erythropoietin and other hematopoietic factors on central cholinergic neurons in vitro and in vivo (1993) (280)
A molecular chaperone inducer protects neurons from ER stress (2008) (241)
Intracellular Aβ42 activates p53 promoter: a pathway to neurodegeneration in Alzheimer's disease (2005) (237)
Differential Expression of NK T Cell Vα24JαQ Invariant TCR Chain in the Lesions of Multiple Sclerosis and Chronic Inflammatory Demyelinating Polyneuropathy1 (2000) (236)
Stress induces neuronal death in the hippocampus of castrated rats (1992) (215)
Tissue preconditioning may explain concentric lesions in Baló's type of multiple sclerosis. (2005) (208)
FTDP‐17 mutations N279K and S305N in tau produce increased splicing of exon 10 (1999) (205)
Changes in brain morphology in Alzheimer disease and normal aging: is Alzheimer disease an exaggerated aging process? (2001) (193)
Endogenous Glucocorticoids Are Essential for Maintaining Prefrontal Cortical Cognitive Function (2004) (188)
Interleukin 3 as a trophic factor for central cholinergic neurons in vitro and in vivo (1990) (180)
Chronic stress differentially regulates glucocorticoid negative feedback response in rats (2001) (171)
Chronic cerebral hypoperfusion induced by right unilateral common carotid artery occlusion causes delayed white matter lesions and cognitive impairment in adult mice (2008) (170)
Frequency of tau gene mutations in familial and sporadic cases of non-Alzheimer dementia. (2001) (169)
Oral vaccination with a viral vector containing Aβ cDNA attenuates age‐related Aβ accumulation and memory deficits without causing inflammation in a mouse Alzheimer model (2007) (154)
A distinct familial presenile dementia with a novel missense mutation in the tau gene. (1999) (153)
Costimulation-Dependent Modulation of Experimental Autoimmune Encephalomyelitis by Ligand Stimulation of Vα14 NK T Cells1 (2001) (142)
Notch3 ectodomain is a major component of granular osmiophilic material (GOM) in CADASIL (2006) (128)
Mechanism of natural killer (NK) cell regulatory role in experimental autoimmune encephalomyelitis (2005) (122)
Apomorphine treatment in Alzheimer mice promoting amyloid‐β degradation (2011) (116)
Differential expression of NK T cell V alpha 24J alpha Q invariant TCR chain in the lesions of multiple sclerosis and chronic inflammatory demyelinating polyneuropathy. (2000) (114)
Intracellular Abeta42 activates p53 promoter: a pathway to neurodegeneration in Alzheimer's disease. (2005) (111)
Aging attenuates glucocorticoid negative feedback in rat brain (2009) (101)
Chronic intermittent hypoxia/reoxygenation facilitate amyloid-β generation in mice. (2013) (99)
Development of a safe oral Abeta vaccine using recombinant adeno-associated virus vector for Alzheimer's disease. (2004) (93)
Functional redundancy of the Notch gene family during mouse embryogenesis: analysis of Notch gene expression in Notch3-deficient mice. (2005) (93)
Mutant presenilin 2 transgenic mice. A large increase in the levels of Abeta 42 is presumably associated with the low density membrane domain that contains decreased levels of glycerophospholipids and sphingomyelin. (2000) (92)
Persistent depressive state after chronic stress in rats is accompanied by HPA axis dysregulation and reduced prefrontal dopaminergic neurotransmission (2008) (84)
Age-related spatial working memory impairment is caused by prefrontal cortical dopaminergic dysfunction in rats (2009) (83)
Identification of a putative amyloid A4‐generating enzyme as a prolyl endopeptidase (1990) (82)
The pathogenesis of CADASIL: an update (2004) (81)
Experimental allergic encephalomyelitis induced by proteolipid apoprotein in Lewis rats (1986) (80)
Genetic, clinical and pathological studies of CADASIL in Japan: a partial contribution of Notch3 mutations and implications of smooth muscle cell degeneration for the pathogenesis (2003) (79)
Ia expression in chronic relapsing experimental allergic encephalomyelitis induced by long-term cultured T cell lines in mice. (1986) (78)
Apoptotic neurons in Alzheimer's disease frequently show intracellular Abeta42 labeling. (2001) (77)
X11L2, a new member of the X11 protein family, interacts with Alzheimer's beta-amyloid precursor protein. (1999) (76)
High manganese, a risk for Alzheimer's disease: high manganese induces amyloid-β related cognitive impairment. (2014) (76)
Chronic experimental allergic encephalomyelitis in guinea pigs induced by proteolipid protein (1985) (75)
Neurotrophic effect of hematopoietic cytokines on cholinergic and other neurons in vitro (1995) (75)
Three novel alternatively spliced isoforms of the human beta-site amyloid precursor protein cleaving enzyme (BACE) and their effect on amyloid beta-peptide production (2001) (72)
Intracellular accumulation of toxic turn amyloid-β is associated with endoplasmic reticulum stress in Alzheimer's disease. (2013) (69)
An experimental analysis of interlamellar tight junctions in amphibian and mammalian C.N.S. myelin (1978) (69)
Familial Alzheimer's disease genes in Japanese (1998) (69)
Chronic stress impairs rotarod performance in rats: implications for depressive state (2002) (68)
Alzheimer's disease amyloid beta-clipping enzyme (APP secretase): identification, purification, and characterization of the enzyme. (1991) (67)
DM-20, a proteolipid apoprotein, is an encephalitogen of acute and relapsing autoimmune encephalomyelitis in mice. (1986) (67)
Familial frontotemporal dementia and parkinsonism with a novel mutation at an intron 10+11‐splice site in the tau gene (2001) (66)
Significance of intracellular Abeta42 accumulation in Alzheimer's disease. (2002) (65)
Effect of growth factors and cytokines on expression of amyloid beta protein precursor mRNAs in cultured neural cells. (1993) (64)
A clinical comparative study of multiple sclerosis and neuro-Behçet's syndrome. (1980) (63)
HLA-DP beta and susceptibility to multiple sclerosis: an analysis of caucasoid and Japanese patient populations. (1990) (61)
Immunization therapy for Alzheimer disease: a comprehensive review of active immunization strategies. (2010) (61)
Alzheimer's disease with spastic paresis and cotton wool type plaques (2002) (60)
Anxiolytic effect of a herbal medicine, yokukansan, in aged rats: involvement of serotonergic and dopaminergic transmissions in the prefrontal cortex. (2010) (59)
Giant axonal neuropathy (1975) (57)
Alzheimer's disease-associated presenilin 2 interacts with DRAL, an LIM-domain protein. (2000) (57)
Enhanced generation of intracellular Aβ42 amyloid peptide by mutation of presenilins PS1 and PS2 (2004) (57)
Glypican‐1 as an Aβ binding HSPG in the human brain: Its localization in DIG domains and possible roles in the pathogenesis of Alzheimer's disease (2004) (56)
Decreased beta-amyloid and increased abnormal Tau deposition in the brain of aged patients with leprosy. (1994) (55)
Pro‐apoptotic effect of presenilin 2 (PS2) overexpression is associated with down‐regulation of Bcl‐2 in cultured neurons (2001) (55)
Developmental and differential expression of beta amyloid protein precursor mRNAs in mouse brain. (1990) (55)
Altered localization of amyloid precursor protein under endoplasmic reticulum stress. (2006) (55)
Studies of experimental allergic encephalomyelitis by using encephalitogenic T cell lines and clones in euthymic and athymic mice. (1986) (54)
Aquaporin-4 astrocytopathy in Baló’s disease (2010) (53)
Extensive loss of connexins in Baló’s disease: evidence for an auto-antibody-independent astrocytopathy via impaired astrocyte–oligodendrocyte/myelin interaction (2012) (53)
Serial analysis of gene expression in a microglial cell line (1999) (52)
Isolation of human delta-catenin and its binding specificity with presenilin 1. (1999) (52)
Insulin-like growth factor II promotes in vitro cholinergic development of mouse septal neurons: comparison with the effects of insulin-like growth factor I (1994) (51)
The twenty-four KDa C-terminal tau fragment increases with aging in tauopathy mice: implications of prion-like properties. (2015) (50)
Two brothers with frontotemporal dementia and parkinsonism with an N279K mutation of the tau gene (2000) (50)
Parvalbumin-immunoreactive neurons in the human central nervous system are decreased in Alzheimer's disease (2004) (49)
Amino‐truncated amyloid β‐peptide (Aβ5‐40/42) produced from caspase‐cleaved amyloid precursor protein is deposited in Alzheimer’s disease brain (2004) (48)
Missense mutation of S182 gene in Japanese familial Alzheimer's disease (1995) (48)
CADASIL-causing mutations do not alter Notch3 receptor processing and activation (2006) (47)
Putative N‐terminal splitting enzyme of amyloid A4 peptides is the multicatalytic proteinase, ingensin, which is widely distributed in mammalian cells (1989) (46)
Sequence analysis of presenilin-1 gene mutation in Japanese Alzheimer's disease patients (1996) (46)
Acute autonomic and sensory neuropathy associated with elevated Epstein-Barr virus antibody titre. (1982) (45)
Analysis of proteolipid protein (PLP)-specific T cells in multiple sclerosis: identification of PLP 95-116 as an HLA-DR2,w15-associated determinant. (1995) (45)
Effect of chronic stress on cholinergic transmission in rat hippocampus (2001) (44)
Hla-DR2-restricted responses to proteolipid protein 95-116 peptide cause autoimmune encephalitis in transgenic mice. (2000) (44)
Humoral immune responses to myelin basic protein, cerebroside and ganglioside in chronic relapsing experimental allergic encephalomyelitis of the guinea pig (1985) (43)
Saiko-ka-ryukotsu-borei-to, a herbal medicine, ameliorates chronic stress-induced depressive state in rotarod performance (2003) (42)
Neuropathological and biochemical studies in Fabry's disease (2004) (41)
Determination of a cleavage site of presenilin 2 protein in stably transfected SH-SY5Y human neuroblastoma cell lines. (1997) (41)
Trophic effect of granulocyte-macrophage colony-stimulating factor on central cholinergic neurons in vitro (1990) (41)
Multiple sclerosis cerebrospinal fluid produces myelin lesions in tadpole optic nerves. (1976) (40)
Mutations of the Notch3 Gene in Non-Caucasian Patients with Suspected CADASIL Syndrome (2001) (40)
Molecular cloning of human Fe65L2 and its interaction with the Alzheimer's β-amyloid precursor protein (1999) (39)
Overexpression of Presenilin‐2 Enhances Apoptotic Death of Cultured Cortical Neurons (2000) (39)
Japanese Huperzia serrata extract and the constituent, huperzine A, ameliorate the scopolamine-induced cognitive impairment in mice (2015) (37)
Comparison between brain CT and MRI for voxel-based morphometry of Alzheimer's disease (2013) (37)
Both N‐terminal and C‐terminal fragments of Presenilin 1 colocalize with neurofibrillary tangles in neurons and dystrophic neurites of senile plaques in Alzheimer's disease (1998) (37)
Heterogeneous induction of 72-kDa heat shock protein (HSP72) in cultured mouse oligodendrocytes and astrocytes (1992) (37)
Genetic Analysis in Patients with Familial and Sporadic Frontotemporal Dementia: Two Tau Mutations in Only Familial Cases and No Association with Apolipoprotein ε4 (2001) (36)
Thioredoxin from activated macrophages as a trophic factor for central cholinergic neurons in vitro. (1993) (36)
Sendai virus vector‐mediated brain‐derived neurotrophic factor expression ameliorates memory deficits and synaptic degeneration in a transgenic mouse model of Alzheimer's disease (2012) (35)
Clioquinol's Return: Cautions from Japan (2001) (35)
Amino-truncated amyloid beta-peptide (Abeta5-40/42) produced from caspase-cleaved amyloid precursor protein is deposited in Alzheimer's disease brain. (2004) (34)
Developmental and aging changes in the expression patterns of beta-amyloid in the brains of normal and down syndrome cases (1990) (34)
Susceptibility to proteolipid apoprotein and its encephalitogenic determinants in mice. (1990) (34)
Characterization of an amyloid precursor protein-binding protein Fe65L2 and its novel isoforms lacking phosphotyrosine-interaction domains. (2002) (33)
Genetic Risk Factors in Japanese Alzheimer’s Disease Patients: α1-ACT, VLDLR, and ApoE (1998) (33)
Glypican-1 as an Abeta binding HSPG in the human brain: its localization in DIG domains and possible roles in the pathogenesis of Alzheimer's disease. (2004) (33)
No effect of anti-leprosy drugs in the prevention of Alzheimer’s disease and β-amyloid neurotoxicity (1999) (33)
Long‐term oral intake of aluminium or zinc does not accelerate Alzheimer pathology in AβPP and AβPP/tau transgenic mice (2012) (32)
Association of a particular amino acid sequence of the HLA‐DR β1 chain with HTLV‐I‐associated myelopathy (1990) (30)
Mutational Analysis of Intrinsic Regions of Presenilin 2 That Determine Its Endoproteolytic Cleavage and Pathological Function* (2000) (30)
Autoimmune Demyelination in the Central Nervous System a (1988) (29)
Identification of autoimmune T-cells among in vivo expanded CD25+ T-cells in multiple sclerosis (1998) (29)
Dopamine-receptor stimulation in the prefrontal cortex ameliorates stress-induced rotarod impairment (2002) (29)
Autophagy is involved in oral rAAV/Aβ vaccine-induced Aβ clearance in APP/PS1 transgenic mice (2015) (27)
Demyelination induced by T cell lines and clones specific for myelin basic protein in mice. (1987) (27)
Saiko-ka-ryukotsu-borei-to, an herbal medicine, prevents chronic stress-induced disruption of glucocorticoid negative feedback in rats. (2002) (26)
Intracellular amyloid beta-protein and its associated molecules in the pathogenesis of Alzheimer's disease. (2006) (26)
Ameliorative effect of traditional Japanese medicine yokukansan on age-related impairments of working memory and reversal learning in rats (2011) (26)
Orbitofrontal dopaminergic dysfunction causes age-related impairment of reversal learning in rats (2010) (26)
Interleukin‐3 and Interleukin‐3 Receptors in the Brain a (1998) (25)
Familial frontotemporal dementia with a P301L tau mutation in Japan (2000) (25)
Reflex sympathetic dystrophy (causalgia) treatment with guanethidine. (1983) (25)
Cortical deafness in multiple sclerosis (1981) (24)
Abnormal intracellular trafficking of high affinity nerve growth factor receptor, Trk, in stable transfectants expressing presenilin 1 protein. (2005) (24)
Semple rabies vaccine: presence of myelin basic protein and proteolipid protein and its activity in experimental allergic encephalomyelitis (1989) (24)
Production of interleukin-3 by murine central nervous system neurons (1994) (24)
Neuropathological Features of MS in Japan (1982) (23)
HLA-DRB1, -DQA1, -DQB1, -DPA1 and -DPB1 genes in Japanese multiple sclerosis patients. (1991) (23)
Hexachlorophene-induced myelin lesions in the amphibian central nervous system A freeze-fracture study (1978) (23)
The penetration of fluorescein-conjugated and electron-dense tracer proteins into Xenopus tadpole optic nerves following perineural injection (1976) (23)
Antibodies to proteolipid apoprotein in chronic relapsing experimental allergic encephalomyelitis (1986) (23)
Studies of experimental allergic encephalomyelitis in old mice (1990) (22)
A novel mutation at position +11 in the intron following exon 10 of the tau gene in FTDP-17. (2002) (22)
Arg133Cys mutation of Notch3 in two unrelated Japanese families with CADASIL. (2000) (22)
Juzen-taiho-to, an herbal medicine, activates and enhances phagocytosis in microglia/macrophages. (2008) (21)
Association between Tau polymorphism and male early-onset Alzheimer's disease (2004) (20)
An Oral Aβ Vaccine Using a Recombinant Adeno-Associated Virus Vector in Aged Monkeys: Reduction in Plaque Amyloid and Increase in Aβ Oligomers. (2016) (20)
TCR repertoire to proteolipid protein (PLP) in multiple sclerosis (MS): homologies between PLP-specific T cells and MS-associated T cells in TCR junctional sequences. (1996) (20)
Autonomic regulation of experimental autoimmune encephalomyelitis in IL-4 knockout mice (1999) (20)
Molecular cloning of human Fe65L2 and its interaction with the Alzheimer's beta-amyloid precursor protein. (1999) (19)
Subsets of lymphoid cells in blood and thymus in myasthenia gravis Monoclonal Antibody Analysis (1983) (19)
Immunohistochemical study of Alzheimer's disease using antibodies to synthetic amyloid and fibronectin (1988) (19)
HSP72 induction by heat stress is not universal in mammalian neural cell lines (1994) (19)
Binding of an SJL T cell clone specific for myelin basic protein to SJL brain microvessel endothelial cells is inhibited by anti-VLA-4 or its ligand, anti-vascular cell adhesion molecule 1 antibody (1993) (19)
Enhancement of activation of caspases by presenilin 1 gene mutations and its inhibition by secretase inhibitors. (2009) (18)
Constitutive expression of 65-kDa heat shock protein (HSP65)-like immunoreactivity in cultured mouse oligodendrocytes (1992) (18)
Analysis of T cell antigen receptors of myelin basic protein specific T cells in SJL/J mice demonstrates an alpha chain CDR3 motif associated with encephalitogenic T cells. (1994) (18)
The therapeutic effects of the herbal medicine, Juzen-taiho-to, on amyloid-beta burden in a mouse model of Alzheimer's disease. (2010) (18)
Increase in p53 protein levels by presenilin 1 gene mutations and its inhibition by secretase inhibitors. (2009) (17)
Identification of astrocyte-derived immune suppressor factor that induces apoptosis of autoreactive T cells (2011) (17)
Passive transfer of experimental allergic encephalomyelitis induced by proteolipid apoprotein (1986) (17)
Genome structure and chromosomal mapping of the gene for Fe65L2 interacting with Alzheimer's beta-amyloid precursor protein. (1999) (17)
Saikokaryukotsuboreito, a herbal medicine, prevents chronic stress-induced dysfunction of glucocorticoid negative feedback system in rat brain (2007) (17)
Demonstration of interleukin‐3 receptor‐associated antigen in the central nervous system (1995) (17)
A novel monoclonal antibody specific for the amino-truncated β-amyloid Aβ5-40/42 produced from caspase-cleaved amyloid precursor protein (2007) (16)
Saikokaryukotsuboreito, a herbal medicine, prevents chronic stress-induced anxiety in rats: comparison with diazepam (2008) (16)
Urinary homocysteic acid levels correlate with mini-mental state examination scores in Alzheimer's disease patients. (2012) (16)
Clinical Picture of Multiple Sclerosis in Asia (1982) (16)
Genomic organization of the human X11L2 gene (APBA3), a third member of the X11 protein family interacting with Alzheimer's beta-amyloid precursor protein. (1999) (15)
What transgenic and knockout mouse models teach us about experimental autoimmune encephalomyelitis. (2000) (15)
Ia restriction of murine encephalitogenic T-cell lines in vitro and in vivo (1985) (14)
Baló's concentric sclerosis in a 4-year-old Japanese infant (1998) (14)
Carbamazepine for painful crises in Fabry's disease. (1973) (14)
A novel beta-site amyloid precursor protein cleaving enzyme (BACE) isoform regulated by nonsense-mediated mRNA decay and proteasome-dependent degradation (2007) (14)
In vivo test for myelinotoxicity of cerebrospinal fluid (1977) (14)
Familial amyotrophic lateral sclerosis and parkinsonism-dementia complex--tauopathy without mutations in the tau gene? (2003) (14)
T-T cellular interaction between CD4-CD8- regulatory T cells and T cell clones presenting TCR peptide. Its implication for TCR vaccination against experimental autoimmune encephalomyelitis. (1996) (13)
Suppression of experimental allergic encephalomyelitis by 15-deoxyspergualin (1987) (13)
Tau gene mutations in frontotemporal dementia and Parkinsonism linked to chromosome 17 and their role in neurodegenerative process (2001) (12)
Elevated levels of anti-CD9 antibodies in the cerebrospinal fluid of patients with subacute sclerosing panencephalitis. (2002) (12)
[Report of a patient with CADASIL having a novel missense mutation of the Notch 3 gene--association with alopecia and lumbar herniated disk]. (2001) (12)
Lymphokine production by encephalitogenic and non-encephalitogenic T-cell clones reactive to the same antigenic determinant (1990) (12)
Identification of a Notch3 mutation in a Japanese CADASIL family. Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy. (1999) (12)
A New Myelin‐Deficient Mutant Hamster: Biochemical and Morphological Studies (1986) (12)
A family of membrane proteins associated with presenilin expression and γ‐secretase function (2008) (12)
A clinical and pathological study of a Japanese case of Amyotrophic Lateral Sclerosis/Parkinsonism-Dementia Complex with family history (2003) (12)
Effects of presenilin N-terminal fragments on production of amyloid β peptide and accumulation of endogenous presenilins (1999) (12)
Demonstration of amyloid β-protein secretion in a mouse neuronal cell line (1994) (11)
3H-thymidine autoradiography of CSF cells in primary reticulum cell sarcoma of the brain (1975) (11)
Mucosal immunotherapy in an Alzheimer mouse model by recombinant Sendai virus vector carrying Aβ1-43/IL-10 cDNA. (2011) (11)
[Astrocytopathy in neuromyelitis optica, multiple sclerosis and Baló's disease]. (2011) (11)
Rapidly proliferating glial cells isolated from adult mouse brain have a differentiative capacity in response to cyclic AMP (1994) (11)
A Study of a Supplement Containing Huperzine A and Curcumin in Dementia Patients and Individuals with Mild Cognitive Impairment. (2018) (11)
Recognition of alloantigens and induction of experimental allergic encephalomyelitis by a murine encephalitogenic T cell clone (1987) (11)
Suppression of glucocorticoid secretion induces a behaviorally depressive state in rotarod performance in rat (2008) (11)
Marchiafava-bignami disease, striatal degeneration, and other neurological complications of chronic alcoholism in a Japanese (2004) (10)
Biochemical and genetic studies in two families with Fabry disease. (1974) (10)
A unifying model for functional difference and redundancy of presenilin-1 and -2 in cell apoptosis and differentiation. (2003) (10)
Development and Characterization of a TAPIR-Like Mouse Monoclonal Antibody to Amyloid-β (2008) (10)
Significantly increased frequency of the apolipoprotein E ϵ4 allele in elderly non-demented leprosy patients (1996) (9)
Distinct microglial and macrophage distribution patterns in the concentric and lamellar lesions in Baló's disease and neuromyelitis optica spectrum disorders (2020) (9)
[Development of new drugs for Alzheimer's disease]. (2010) (9)
Coexistence of cholinergic, catecholaminergic, serotonergic, and glutamatergic neurotransmitter markers in mouse clonal hybrid neurons derived from the septal region (1992) (9)
T lymphocyte lines and clones selected against synthetic myelin basic protein 82–102 peptide from Japanese multiple sclerosis patients (1993) (9)
Prophylactic and Therapeutic Effect of Bactobolin on Autoimmune Encephalomyelitis (1987) (9)
Neurite promoting activity of collagens on embryonic neurons: decreased effect at the postnatal stage. (1993) (9)
Novel mutation of the Notch3 gene in a Japanese patient with CADASIL (2007) (9)
Amyloid β peptide binds a novel death‐inducing protein, AB‐DIP (2005) (8)
Interleukin-3 promotes neurite outgrowth and elevates choline acetyltransferase activity in vitro. (1989) (8)
Assignment of a familial Alzheimer's disease locus between D14S289 and D14S53 (1994) (8)
Cellular and molecular aspects of the pathomechanism and therapy of murine experimental allergic encephalomyelitis. (1989) (8)
The role of locally retained antigens in chronic relapsing experimental allergic encephalomyelitis in guinea pigs. (1984) (8)
Juzen-Taiho-to, an herbal medicine, promotes the differentiation of transplanted bone marrow cells into microglia in the mouse brain injected with fibrillar amyloid β. (2014) (8)
Suppression of glucocorticoid secretion enhances cholinergic transmission in rat hippocampus (2008) (8)
CXCR4 is the primary receptor for feline immunodeficiency virus in astrocytes (2001) (7)
High expression on Kunitz-type protease inhibitor-containing substances in the cerebral vessels of patients with Down syndrome. (1994) (7)
Nasal vaccine delivery attenuates brain pathology and cognitive impairment in tauopathy model mice (2020) (7)
[Case of adrenoleukodystrophy presenting as spinocerebellar degeneration]. (1983) (7)
[CADASIL: clinical analysis of CADASIL and CADASIL-like disorders in Japan]. (2000) (7)
E-PTA stains oligodendroglial surface membranes and microtubules in optic nerves during myelination (1979) (7)
Delayed type skin response to myelin basic protein in chronic relapsing experimental allergic encephalomyelitis (1983) (7)
Necessity of continuous antigenic stimulation by the locally retained antigens in chronic relapsing experimental allergic encephalomyelitis (1984) (7)
Demyelinating activity of cerebrospinal fluid from multiple sclerosis patients tested in a new model system, the optic nerves of xenopus tadpoles. (1975) (6)
Nasal vaccine delivery attenuates brain pathology and cognitive impairment in tauopathy model mice (2020) (6)
Alpha-1-Antichymotrypsin Is Not Associated with the Increased Frequency of Apolipoprotein-E- Epsilon-4 Allele in Elderly Non-Demented Leprosy Patients (1997) (6)
CSF Immunoglobulin and Virus Antibody in Japanese MS: A Comparative Study (1982) (6)
Cerebral cortical amyloid protein precursor mRNA expression is similar in Alzheimer's disease and other neurodegenerative diseases (1992) (6)
Alkaline treatment after X-Gal staining reaction for Escherichia coli beta-galactosidase enhances sensitivity. (2000) (6)
Modulation of experimental allergicencephalomyelitis (EAE): Suppression of active reinduction of eae in rats recovered from passively transferred disease (1986) (6)
Chronic relapsing experimental allergic encephalomyelitis in strain 13 guinea pigs; presence of myelin basic protein in the local tissue long after the immunization. (1982) (5)
A family of membrane proteins associated with presenilin expression and gamma-secretase function. (2008) (5)
c954C→T polymorphism in the Fe65L2 gene is associated with early‐onset Alzheimer's disease (2002) (5)
Decreased expression of MAP-2 and GAD in the brain of cats infected with feline immunodeficiency virus. (2001) (5)
Molecular basis of Alzheimer's disease: From amyloid hypothesis to treatment in the foreseeable future (2004) (5)
Establishment of mouse-immortalized hybrid clones expressing characteristics of differentiated neurons derived from the cerebellar and brain stem regions. (1992) (5)
Effects of Ferulic Acid and Angelica archangelica Extract (Feru-guard ®) on Mild Cognitive Impairment: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Prospective Trial (2020) (4)
A novel monoclonal antibody specific for the amino-truncated beta-amyloid Abeta5-40/42 produced from caspase-cleaved amyloid precursor protein. (2007) (4)
Recovery mechanisms from experimental allergic encephalomyelitis in rats: analyses by using encephalitogenic T cell line. (1987) (4)
Autoproliferative and self-reactive T-cell lines from patients with HTLV-I-associated myelopathy. (1990) (4)
Adrenoleukodystrophy presenting as spinocerebellar degeneration (1983) (4)
Concentric Sclerosis (Baló's Disease) (2010) (4)
Autonomic Regulation of Experimental Autoimmune Encephalomyelitis: The Role of Interferon-γ (2002) (4)
Cloning of the cDNA encoding rat presenilin-2. (1998) (4)
[Immunotherapy for Alzheimer's disease targeting Aβ]. (2016) (4)
[Mucosal immunotherapy for alzheimer's disease with viral vectors]. (2007) (3)
[Significance of intracellular A beta in Alzheimer's disease]. (2002) (3)
Notch3 gene in CADASIL syndrome: mutation frequencies in Japanese and its expression and processing (2001) (3)
Autoimmune demyelination (1987) (3)
[Vaccination therapy for Alzheimer's disease]. (2007) (3)
Decorated plaques in Alzheimer's disease (2009) (3)
Microtubule associated protein (tau) gene variability in patients with frontotemporal dementia. (2002) (3)
Alzheimer's disease: Mechanisms and development of therapeutic strategies (2003) (3)
[A case of CADASIL (cerebral autosomal dominant arteriopathy with subcortical infarcts and lekoencephalopathy) with Notch 3 (Arg169Cys) mutation and typical granular osmiophilic materials in peripheral small arteries]. (2004) (3)
Effect of thymic hormones on induction of experimental allergic encephalomyelitis in old mice. (1990) (3)
Experimental allergic encephalomyelitis: suppression with SD-170, a new synthetic drug. (1981) (3)
[A typical adult case of Fabry's disease without angiokeratoma and hypohidrosis: biochemical and morphological studies]. (1983) (3)
Early and Late Development of Notch3 in Human Brains (2005) (3)
Cytotoxic and suppressor activities in patients with HTLV-I-associated myelopathy (1991) (3)
[Concentric sclerosis--with special reference to the high incidence of this unusual demyelinating disease in the Philippines]. (1984) (3)
Evidence that brain capillary endothelial cells can be infected with murine leukaemia retrovirus, LP-BM5. (1996) (3)
[Lipidosis with vertical gaze palsy, macular degeneration, and sphingomyelinase deficiency]. (1982) (2)
Alzheimer's disease vaccines: promises and pitfalls (2011) (2)
Secretion Kinetics of Alzheimer′s Amyloid β-Protein Differs from Secreted β-Amyloid Precursor Protein (1995) (2)
In vivo and in vitro studies of the prevention of proteolipid apoprotein-induced murine experimental allergic encephalomyelitis by monoclonal antibody against L3T4 (1988) (2)
Preparation of whole mounts of rabbit retina for examination with the differential-interference microscope: a technique for morphological studies of CNS demyelination (1977) (2)
Development and characterization of a TAPIR-like mouse monoclonal antibody to amyloid-beta. (2008) (2)
The decrement of muscarinic receptor-mediated calcium influx by overexpression of APP in a mouse cholinergic cell line. (1994) (2)
[A case of neuronal ceroid-lipofuscinosis (Jansky-Bielshowsky type): morphological, biochemical and electrophysiological studies (author's transl)]. (1981) (2)
Enriched cultures of differentiated neurons from mouse embryo whole brain by using extracellular matrix constituents (1993) (2)
An α‐chain TCR CDR3 peptide can enhance EAE induced by myelin basic protein or proteolipid protein (1996) (2)
Aclinical comparative study ofmultiple sclerosis and neuro-Behcet's syndrome (1980) (2)
The Role of Natural Killer (NK) Cells in Experimental Autoimmune Encephalomyelitis (EAE) and Multiple Sclerosis (MS) (2011) (2)
[A view for understanding the pathogenesis of multiple sclerosis]. (1995) (2)
Aβ induces endoplasmic reticulum stress causing possible proteasome impairment via the endoplasmic reticulum–associated degradation pathway (2006) (2)
Homocysteic Acid in Blood Can Detect Mild Cognitive Impairment: A Preliminary Study (2020) (2)
[Development of antibodies for immunotherapy of Alzheimer's disease]. (2012) (2)
Dysmorphic type of sialidosis: Studies on autonomic nervous system and cerebral evoked potentials (1983) (2)
Experimental Allergic Encephalomyelitis Mediated by Murine Encephalitogenic T‐Cell Lines Specific for Myelin Proteolipid Apoprotein (1988) (2)
Pathogenesis of AD is similar to that of uremic encephalopathy of Homocysteic acid. (2011) (1)
[Immunological abnormalities in multiple sclerosis]. (1983) (1)
Significance of intracellular A beta 42 accumulation in Alzheimer s disease (2002) (1)
An epidemiological study of neurological diseases, especially incurable diseases in the Philippines (1984) (1)
[Fabry's disease--case report and treatment of painful crises by carbamazepine]. (1973) (1)
[Case of dysmorphic type of sialidosis: autonomic nervous system function and cerebral electrophysiological studies]. (1983) (1)
Differential expression of presenilin-α and -β (PSα and PSβ) in Xenopus laevis: embryonic phosphorylation of PSα (2003) (1)
Intracellular Aβ42 deposits and neurodegeneration in Alzeimer's disease (2000) (1)
P4-321 Nasal vaccine for Alzheimer’s disease with recombinant sendaivirus vector expressing Aβ 1-43/IL-10 (2006) (1)
[A case of multiple sclerosis with transient cortical deafness (author's transl)]. (1979) (1)
Abrogation of spleen macrophage suppressive activity by 15-deoxyspergualin. (1989) (1)
[Case of rigid spine syndrome]. (1983) (1)
[Current trend of immunotherapy for Alzheimer's disease]. (2011) (1)
Significantly increased frequency of the apolipoprotein E epsilon 4 allele in elderly non-demented leprosy patients. (1996) (1)
Absence of antibodies to HTLV‐1 in sera from Hungarian MS patients (1988) (1)
O3-06-04 Oral Abeta vaccine is safe and effective (2004) (1)
[Optic and peripheral neuritis following chloramphenicol therapy (author's transl)]. (1973) (1)
Juvenile neurogenic muscle atrophy with lysosomal enzyme deficiencies: new disease or variant of mucopolysaccharidosis? (2004) (1)
[Immunotherapy targeting on Abeta for Alzheimer disease]. (2011) (1)
Amyloid beta protein‐related death‐inducing protein induces G2/M arrest: Implications for neurodegeneration in Alzheimer's disease (2007) (1)
Activation of effector cells of experimental allergic encephalomyelitis in Lewis rats: comparison of T-cell lines with primary cultured lymph node cells. (1986) (1)
Frontotemporal dementia with tauopathy: A review and preliminary immunohistochemical study of tau kinases and phosphatases (1999) (1)
[A simple form of adult onset familial sudanophilic leukodystrophy manifesting pyramidal tract involvement and presenile dementia]. (1983) (1)
[Immunotherapy of Alzheimer's disease by Abeta vaccination]. (2009) (1)
Demonstration of amyloid beta-protein secretion in a mouse neuronal cell line. (1994) (1)
Two RFLPS (AciI; c954C/T and FokI; c1023FokIT/C) within the coding region of the gene for human Fe65L2, a protein which interacts with Alzheimer beta‐amyloid precursor protein (2000) (1)
Heat-inducible expression of 72-kilodalton heat shock protein (HSP72) on cultured mouse oligodendrocytes and astrocytes (1991) (1)
8th International Congress of Neuroimmunology (2007) (1)
[A case of mucopolysaccharidosis III A (Sanfilippo) with retinal changes]. (1982) (1)
Differential expression of presenilin-alpha and -beta (PSalpha and PSbeta) in Xenopus laevis: embryonic phosphorylation of PSalpha. (2003) (0)
[Antibody therapy for Alzheimer's disease]. (2011) (0)
1403 α1-Antichymotrypsin is not associated with the increased frequency of apolipoprotein Eϵ4 allele in non-demented leprosy patients (1997) (0)
[Kampo treatment for Alzheimer's disease]. (2011) (0)
Electron microscopic demonstration of polysaccharides in central and peripheral myelin by thiosemicarbazide-protein-silver staining (1985) (0)
Differential roles of NK and NK-T cells for regulation of EAE (1998) (0)
494 Increased frequency of apolipoprotein E 4 allele in nondemented elderly patients with leprosy (1996) (0)
MECHANISIM of SUPPRESSION of COLCHICINE on EAE (1986) (0)
342 Immunohistochemical localization of insulin-like growth factor ii receptors in mouse brain-in relationship to choline acetyltransferase immunoreactivity (1996) (0)
[Clinical practice of dementia]. (2008) (0)
Analysis of PLP-specific T cells suggests T cell receptor CDR3 conservation among human encephalitogenic T cells (1994) (0)
1201 Insulin-like growth factors promotes in vitro cholinergic development of mouse septal neurons (1993) (0)
Aged transgenic mice carrying Alzheimer's presenilin 1 mutation show accelerated neurodegeneration (1999) (0)
[Frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17)]. (2000) (0)
Oral vaccination with a viral vector containing A (cid:1) cDNA attenuates age-related A (cid:1) accumulation and memory deﬁcits without causing inﬂammation in a mouse Alzheimer model (2007) (0)
6. Progress in the Studies of Alzheimer's Disease (2007) (0)
Two RFLPS (AciI; c954C/T and FokI; c1023FokIT/C) within the coding region of the gene for human Fe65L2, a protein which interacts with Alzheimer beta-amyloid precursor protein. (2000) (0)
[A molecular genetic overview of familial dementing disorders]. (2004) (0)
[Mechanisms of demyelination--acute and chronic relapsing experimental allergic encephalomyelitis]. (1984) (0)
[Target antigens in neuroimmunological diseases]. (1994) (0)
Absence of antibody to HTLV-I in sera from patients with multiple sclerosis in Hungary (1987) (0)
Low βAP but high abnormal TAU deposition in aged leprosy patients brain (1994) (0)
[Vaccination therapy for Alzheimer's disease]. (2004) (0)
P1-386 COGNITIVE RECOVERY BY HBF BRAIN FOOD (2014) (0)
[Progress in Alzheimer research]. (2001) (0)
S4-04-01: Oral Aβ vaccine (2008) (0)
The clinial course and prognosis of Japanese multiple sclerosis patients, with special reference to corticosteroid therapy (1983) (0)
FELINE IMMUNODEFICIENCY VIRUS-ASSOCIATED NEURO-PATHOLOGICAL ALTERATIONS INDUCED BY INFLAMMATORY CYTOKINES (1999) (0)
Selective loss of invariant Va24-JaQ+ T-cells in multiple sclerosis (1998) (0)
[A case of demyelinating disease with acute transverse myelitis and polyradiculoneuropathy (author's transl)]. (1978) (0)
[Therapeutic strategies including vaccination]. (2006) (0)
Identification of Putative Amyloid A4-Splitting Enzymes with Two Endopeptidases Widely Distributed in Mammalian Cells (1990) (0)
Mutation and Polymorphism Report (1999) (0)
Extrathymic induction of T cells specific for myelin autoantigens (1994) (0)
P3-027 Proteomic analysis of cerebrospinal fluid in Alzheimer's disease (2004) (0)
Autophagy is involved in oral rAAV/Aβ vaccine-induced Aβ clearance in APP/PS1 transgenic mice (2015) (0)
[Mild cognitive impairment (MCI)--overview]. (2004) (0)
Proteolipid 95–116-specific T cell response in DR2 transgenic mice (1998) (0)
[Is a false image of the senile plaque in elderly Japanese with leprosy?--pathological findings on the immunohistology]. (1994) (0)
DEVELOPMENT OF MIMOTOPES BASED ON Aβ OLIGOMER SPECIFIC MONOCLONAL ANTIBODY (2014) (0)
Secretion kinetics of Alzheimer's amyloid beta-protein differs from secreted beta-amyloid precursor protein. (1995) (0)
[Molecular pathomechanism of autoimmune encephalitis]. (1990) (0)
Oral Aβ Vaccine Using a Recombinant Adeno-Associated Virus Vector in an Alzheimer’s Disease Mouse Model (2008) (0)
[Subacute sensory neuropathy associated with lung cancer (author's transl)]. (1980) (0)
Effectiveness of rehabilitation on the cognitive function impairment in CVD patients (2017) (0)
Expression of presenilin-2 enhances apoptotic death of primary cortical neurons (2000) (0)
MYELIH LESIONS IN OPTIC NERVES OF XEKOPUS TADPOLES PRODUCED BY PERINEURIAL INJECTIOK OF CSF FROM MULTIPLE SCLEROSIS PATIENTS: 52 (1976) (0)
[Case of lepromatous neuritis--a study of neural lesions by neural biopsy]. (1973) (0)
Pathogenic action of homocysteic acid in human (2011) (0)
Neurotrophic Effect of Interleukin-3 (IL-3) and Its Mechanisms of Action in the Nervous System1 (2006) (0)
[Vaccination therapy for Alzheimer's disease]. (2007) (0)
Double-negative suppressor T cells against encephalitogenic T cell clones (1993) (0)
Oral vaccine using viral vectors for Alzheimer's disease: PIB/PET studies in old cynomolgus monkeys (2011) (0)
Contents, Vol. 92, 1990 (1990) (0)
P4-346 Application of molecular chaperone inducer for Alzheimer disease (2006) (0)
[Development of transgenic animal models for Alzheimer's disease]. (2001) (0)
[Identification of Notch 3 mutation in the first Japanese CADASIL family]. (1999) (0)
Association betweenTau polymorphism and male early-onset Alzheimer’s disease (2003) (0)
[Development of prevention and treatment of Alzheimer's disease: a minireview]. (2004) (0)
62 Localization of presenilin in astrocytes and neurons in human brain (1996) (0)
Metabolic and Functional Changes in βAPP Overexpressing Mouse Neuronal Cell Line: Muscarinic Receptor-Mediated Calcium Influx (1995) (0)
[Immunological analysis by using animal models of multiple sclerosis--acute and chronic relapsing EAE]. (1984) (0)
Truncated tau causes microtubule disassembly with aging in tauopathy model mice (2013) (0)
The regulation of choline acetyltransferase by interleukin-3 on septal cholinergic cell line (1994) (0)
Target antigens in the central nervous system (1991) (0)
P3-386: Effect of FAD-related mutant presenilin 1 (PS1) on caspase activity and apoptosis: Implications in familial Alzheimer’s pathogenesis (2006) (0)
COGNITIVE RECOVERY BY HBF BRAIN FOOD (2014) (0)
[Progress in developing anti-Alzheimer drugs]. (2002) (0)
Free amino acid- and “monoamine”-content of immortalized neuronal cell lines (1991) (0)
[Alzheimer's disease due to presenilin mutations]. (2004) (0)
[Concentric sclerosis (Baló)]. (1994) (0)
Analysis of PLP-specific T cells in MS: Identification of PLP 95-116 as HLA-DR2 associated determinant (1994) (0)
Tau gene analysis in Japanese patients with familial and sporadic frontotemporal dementia (2000) (0)
Mechanism of suppression of colchicine on experimental autoimmune encephalomyelitis (1986) (0)
MHC class II-positive-macrophages release a neurotrophic factor in vitro (1992) (0)
Flow cytometric analysis of an immature oligodendrocyte line with a mixed oligodendrocyte-astrocyte phenotype (1991) (0)
Subject Index Vol. 12, 2001 (2001) (0)
Suppression of lymphocyte spontaneous proliferative response by proteolipid protein peptide in patients with HAM/TSP (1994) (0)
Increas ei np5 3Protei nLevel sb yPresenilin 1 Gene Mutations and its Inhibition by Secretase Inhibitors (2009) (0)
Neurotransmitter synthesis by SN6 cell lines, a family of hybrid cell lines of embryonic septal origin (1993) (0)
761. Genotoxicity Free Intranasal Gene Vaccines for Alzheimer's Disease and AIDS with Remarkable Efficacy in Model Animals; Use of a Cytoplasmic RNA Vector, Sendai Virus Vectors (2006) (0)
P4-279 Characteristics of the protein expression of APH-1 (2004) (0)
Contents, Vol. 79, 1986 (1986) (0)
[Concentric sclerosis]. (2004) (0)
Feline immunodeficiency virus-associated neuropathological alterations induced by inflammatory cytokines (1998) (0)
Demonstration of interleukin 3 (IL-3) receptors in murine central nervous system neurons (1994) (0)
603 Gene analysis of familial Alzheimer's disease in Japan (1996) (0)
Suppression of EAE by double-negative (CD4−CD8−) T cells responding to syngeneic encephalitogenic T cell clones (1991) (0)
Suppression of Lymphocyte Spontaneous Response by Proteolipid Protein Peptide HAM/TSP* Proliferative in Patients with (1994) (0)
Monoclonal antibody 3.4A10 reduces Aβ oligomers and attenuates memory impairment in mouse models of Alzheimer's disease (2011) (0)
P2-395: A novel therapeutic strategy for Alzheimer's disease by a molecular chaperone inducer (2008) (0)
Identifying Monoaminergic, GABAergic, and Cholinergic Characteristics in Immortalized Neuronal Cell Lines (1997) (0)
[Treatment of Alzheimer disease: A beta vaccine]. (2004) (0)
A T cell receptor CDR3 peptide that enhances both MBP- and PLP- induced EAE: A possible existence of common regulatory cells (1994) (0)
Contents Vol. 12, 2001 (2001) (0)
Erratum to “A unifying model for functional difference and redundancy of presenilin-1 and -2 in cell apoptosis and differentiation” [Gene 323 (2003) 115–123] (2004) (0)
Autophagy is involved in oral vaccination of anAAV/Aβ vaccine induced Aβ clearance in APP/PS1 transgenic mice. (2015) (0)
Contents, Vol. 83, 1987 (1987) (0)
Recombinant adeno-associated virus vector for the treatment of Alzheimer's disease (2004) (0)
In Memoriam: Dr. Henry de Forest Webster (1927–2012) (2013) (0)
Homocysteic acid in blood can detect mild cognitive impairment (MCI) and MCI due to Alzheimer disease (AD) pathological change (2020) (0)
[3 cases of solitary acrodystrophic neuropathy probably due to alcoholism--with special reference to comparison with hereditary sensory neuropathy]. (1982) (0)
[Molecular genetics of Alzheimer's disease--presenilin and other genes]. (1997) (0)
Monoclonal Antibodies Against Senile Plaque Amyloid in Alzheimer’s Disease (1990) (0)
REGULATION OF AMYLOID PRECURSOR PROTEIN EXPRESSION BY TETRATRICOPEPTIDE REPEAT PROTEIN 2 (TPR2) (2014) (0)
[Cytokines as signal transmitters in the nervous system]. (1997) (0)
[Clinical course and corticosteroid therapy of multiple sclerosis among Japanese patients]. (1983) (0)
P1-155 ER stress is entangled with Aβ pathology (2004) (0)
P4-241 Pathogenesis of intracellular amyloid beta-protein 42 and P53: A novel therapeutic target in Alzheimer’s disease (2006) (0)

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What Schools Are Affiliated With Takeshi Tabira?

Takeshi Tabira is affiliated with the following schools:

Juntendo University