Tamas Bartfai
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Hungarian neuroscientist
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Biology
Tamas Bartfai's Degrees
- PhD Pharmacology Semmelweis University
- Doctorate Medicine Semmelweis University
Why Is Tamas Bartfai Influential?
(Suggest an Edit or Addition)According to Wikipedia, Tamas Bartfai , is a Hungarian neuroscientist with interests in neurotransmission, neuropeptides, prostaglandins, fever, and drug discovery. As of 2015, he is a professor in The Scripps Research Institute, and an adjunct professor at Stockholm University, the University of Oxford, and the University of Pennsylvania. As an author, he is widely held in libraries worldwide.
Tamas Bartfai's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- The role of inflammation in epilepsy (2011) (1402)
- Interleukin-1β Enhances NMDA Receptor-Mediated Intracellular Calcium Increase through Activation of the Src Family of Kinases (2003) (774)
- Cell penetrating PNA constructs regulate galanin receptor levels and modify pain transmission in vivo (1998) (538)
- Powerful anticonvulsant action of IL-1 receptor antagonist on intracerebral injection and astrocytic overexpression in mice. (2000) (451)
- A blood based 12-miRNA signature of Alzheimer disease patients (2013) (421)
- Interleukin‐1β contributes to the generation of experimental febrile seizures (2005) (386)
- Absence of IL-1 signaling and reduced inflammatory response in IL-1 type I receptor-deficient mice. (1997) (363)
- Interleukin (IL)-6 gene expression in the central nervous system is necessary for fever response to lipopolysaccharide or IL-1 beta: a study on IL-6-deficient mice (1996) (359)
- Galanin inhibits acetylcholine release in the ventral hippocampus of the rat: histochemical, autoradiographic, in vivo, and in vitro studies. (1987) (349)
- Transgenic Mice with a Reduced Core Body Temperature Have an Increased Life Span (2006) (347)
- IL-1 receptor/Toll-like receptor signaling in infection, inflammation, stress and neurodegeneration couples hyperexcitability and seizures (2011) (329)
- A Specific Role for NR2A-Containing NMDA Receptors in the Maintenance of Parvalbumin and GAD67 Immunoreactivity in Cultured Interneurons (2006) (304)
- Leukocyte Recruitment in the Cerebrospinal Fluid of Mice with Experimental Meningitis Is Inhibited by an Antibody to Junctional Adhesion Molecule (Jam) (1999) (296)
- Cargo delivery kinetics of cell-penetrating peptides. (2001) (292)
- Neuropeptides: opportunities for drug discovery (2003) (288)
- VE-cadherin-derived cell-penetrating peptide, pVEC, with carrier functions. (2001) (283)
- Regulation of the release of coexisting neurotransmitters. (1988) (279)
- Cytokines and fever. (2004) (266)
- Transthyretin protects Alzheimer's mice from the behavioral and biochemical effects of Aβ toxicity (2008) (261)
- Induction of tumor necrosis factor-α mRNA in the brain after peripheral endotoxin treatment: comparison with interleukin-1 family and interleukin-6 (1993) (260)
- A novel non-transcriptional pathway mediates the proconvulsive effects of interleukin-1beta. (2008) (256)
- The promise of single-cell sequencing (2013) (253)
- Ca2+ Signaling via the Neuronal Calcium Sensor-1 Regulates Associative Learning and Memory in C. elegans (2001) (241)
- X‐ray structure of junctional adhesion molecule: structural basis for homophilic adhesion via a novel dimerization motif (2001) (234)
- Impaired gene and protein expression of exocytotic soluble N-ethylmaleimide attachment protein receptor complex proteins in pancreatic islets of type 2 diabetic patients. (2006) (233)
- Autoradiographic quantitation and anatomical mapping of 125I-galanin binding sites in the rat central nervous system. (1988) (212)
- Galanin-mediated control of pain: enhanced role after nerve injury. (1992) (208)
- Galanin and galanin antagonists: molecular and biochemical perspectives. (1992) (208)
- Cytokine Regulation of Neuronal Survival (1992) (204)
- Evidence for an inhibitory effect of the peptide galanin on dopamine release from the rat median eminence (1987) (197)
- Vasoactive intestinal polypeptide enhances muscarinic ligand binding in cat submandibular salivary gland (1982) (187)
- Cellular translocation of proteins by transportan (2000) (181)
- Activity of centrally administered galanin fragments on stimulation of feeding behavior and on galanin receptor binding in the rat hypothalamus (1990) (170)
- Homophilic Interaction of Junctional Adhesion Molecule* (2000) (165)
- Treatment with an Interleukin 1 beta antibody improves glycemic control in diet-induced obesity. (2008) (162)
- Preparation of metal-chelate complexes and the design of steady-state kinetic experiments involving metal nucleotide complexes. (1979) (162)
- Improved recovery and delayed cytokine induction after closed head injury in mice with central overexpression of the secreted isoform of the interleukin-1 receptor antagonist. (2002) (159)
- Muscarinic acetylcholine receptor (1978) (155)
- Interleukin-18 controls energy homeostasis by suppressing appetite and feed efficiency (2007) (153)
- Galanin reduces release of endogenous excitatory amino acids in the rat hippocampus. (1993) (152)
- M-15: high-affinity chimeric peptide that blocks the neuronal actions of galanin in the hippocampus, locus coeruleus, and spinal cord. (1991) (150)
- Muscarinic autoreceptor regulates acetylcholine release in rat hippocampus: in vitro evidence. (1980) (146)
- A non peptidic corticotropin releasing factor receptor antagonist attenuates fever and exhibits anxiolytic-like activity. (1996) (143)
- Analysis of the Gene Expression Profile Activated by the CC Chemokine Ligand 5/RANTES and by Lipopolysaccharide in Human Monocytes1 (2002) (143)
- Nociceptive responses in interleukin-6-deficient mice to peripheral inflammation and peripheral nerve section. (1997) (140)
- Neuropeptide Y receptor in the rat brain. (1984) (139)
- Galanin--10 years with a neuroendocrine peptide. (1995) (137)
- A low molecular weight mimic of the Toll/IL-1 receptor/resistance domain inhibits IL-1 receptor-mediated responses (2003) (136)
- Galmic, a nonpeptide galanin receptor agonist, affects behaviors in seizure, pain, and forced-swim tests. (2004) (134)
- Coexistence of peptides with classical neurotransmitters (1987) (133)
- Muscarinic supersensitivity induced by septal lesion or chronic atropine treatment (1981) (132)
- Galanin-receptor ligand M40 peptide distinguishes between putative galanin-receptor subtypes. (1993) (130)
- A role for galanin in antidepressant actions with a focus on the dorsal raphe nucleus. (2005) (128)
- Anticonvulsant activity of a nonpeptide galanin receptor agonist (2002) (127)
- Galanin in sensory neurons in the spinal cord. (1992) (126)
- Site(s) and ionic basis of α‐autoinhibition and facilitation of [3H]noradrenaline secretion in guinea‐pig vas deferens (1981) (124)
- Circadian Regulation of Diverse Gene Products Revealed by mRNA Expression Profiling of Synchronized Fibroblasts* 210 (2001) (123)
- Brain mitochondrial uncoupling protein 2 (UCP2): a protective stress signal in neuronal injury. (2002) (122)
- Linear and cyclic N-terminal galanin fragments and analogs as ligands at the hypothalamic galanin receptor. (2009) (121)
- Galanin type 2 receptors regulate neuronal survival, susceptibility to seizures and seizure‐induced neurogenesis in the dentate gyrus (2004) (121)
- N-terminal galanin-(1-16) fragment is an agonist at the hippocampal galanin receptor. (1989) (120)
- Galanin Receptors and Ligands (2012) (119)
- Suppressed kindling epileptogenesis in mice with ectopic overexpression of galanin (2001) (118)
- MyD88-dependent and -independent signaling by IL-1 in neurons probed by bifunctional Toll/IL-1 receptor domain/BB-loop mimetics. (2006) (115)
- Galanin, galanin receptors, and drug targets. (2010) (113)
- Evidence for a role of the neuropeptide galanin in spatial learning (1992) (112)
- Cytokines in neuronal cell types (1993) (112)
- Interleukin‐1 System in CNS Stress (2007) (112)
- Hyperresponsive febrile reactions to interleukin (IL) 1α and IL-1β, and altered brain cytokine mRNA and serum cytokine levels, in IL-1β-deficient mice (1997) (108)
- Galanin receptor and its ligands in the rat hippocampus. (1989) (107)
- Galanin receptor antagonists M40 and C7 block galanin-induced feeding (1993) (105)
- Galanin and its receptors in neurological disorders (2007) (105)
- Uncoupling protein 2 protects dopaminergic neurons from acute 1,2,3,6‐methyl‐phenyl‐tetrahydropyridine toxicity (2005) (101)
- Patterns of seizures, hippocampal injury and neurogenesis in three models of status epilepticus in galanin receptor type 1 (GalR1) knockout mice (2004) (101)
- Delineation of the Proinflammatory Cytokine Cascade in Fever Induction a (1998) (100)
- Galanin receptors: involvement in feeding, pain, depression and Alzheimer's disease. (1997) (100)
- Galanin and spinal nociceptive mechanisms: recent advances and therapeutic implications (2000) (100)
- Design of chimeric peptide ligands to galanin receptors and substance P receptors. (2009) (98)
- Galanin Reduces Carbachol Stimulation of Phosphoinositide Turnover in Rat Ventral Hippocampus by Lowering Ca2+ Influx Through Voltage‐Sensitive Ca2+ Channels (1991) (96)
- Fever: Links with an ancient receptor (1999) (96)
- Neuropeptide expression in rats exposed to chronic mild stresses (2005) (90)
- The novel high-affinity antagonist, galantide, blocks the galanin-mediated inhibition of glucose-induced insulin secretion. (1992) (89)
- Differential release of coexisting neurotransmitters: frequency dependence of the efflux of substance P, thyrotropin releasing hormone and [3H]serotonin from tissue slices of rat ventral spinal cord. (1989) (89)
- Evidence for endogenous inhibition of autotomy by galanin in the rat after sciatic nerve section: demonstrated by chronic intrathecal infusion of a high affinity galanin receptor antagonist (1993) (89)
- Neuropeptides and Neuropeptide Receptors: Drug Targets, and Peptide and Non‐Peptide Ligands: a Tribute to Prof. Dieter Seebach (2012) (88)
- Galanin inhibits the muscarinic stimulation of phosphoinositide turnover in rat ventral hippocampus. (1988) (86)
- Interleukin-1 in adrenal chromaffin cells (1989) (86)
- The neuropeptide galanin modulates behavioral and neurochemical signs of opiate withdrawal (2003) (85)
- Interleukin‐1 receptor accessory protein interacts with the type II interleukin‐1 receptor (1998) (84)
- Neuropeptide Y receptors and the inhibition of adenylate cyclase in the human frontal and temporal cortex (1987) (84)
- Deep sequencing reveals cell-type-specific patterns of single-cell transcriptome variation (2015) (83)
- Efflux of cyclic guanosine 3′,5′-monophosphate from cerebellar slices stimulated by l-glutamate or high K+ or N-methyl-N′-nitro-N-nitrosoguanidine (1986) (83)
- The effects of atropine on [3H]acetylcholine secretion from guinea‐pig myenteric plexus evoked electrically or by high potassium (1982) (81)
- Interleukin‐1 System: Receptors, Ligands, and ICE in the Brain and Their Involvement in the Fever Response (1998) (80)
- Insulin Causes Hyperthermia by Direct Inhibition of Warm-Sensitive Neurons (2009) (79)
- Single cell transcriptomics of hypothalamic warm sensitive neurons that control core body temperature and fever response Signaling asymmetry and an extension of chemical neuroanatomy. (2011) (79)
- Impulse flow dependency of galanin release in vivo in the rat ventral hippocampus. (1994) (77)
- Evaluation of transportan 10 in PEI mediated plasmid delivery assay. (2005) (76)
- Isomerization of the muscarinic receptor . antagonist complex. (1979) (75)
- Effect of interleukin-18 on mouse core body temperature. (2002) (73)
- Galanin Acts at GalR1 Receptors in Spinal Antinociception: Synergy with Morphine and AP-5 (2004) (71)
- Inducible expression of the long pentraxin PTX3 in the central nervous system (2000) (71)
- Regulation of neuropeptide Y (NPY) binding by guanine nucleotides in the rat cerebral cortex (1984) (69)
- A galanin-mastoparan chimeric peptide activates the Na+,K+-ATPase and reverses its inhibition by ouabain (1996) (69)
- A novel, systemically active, selective galanin receptor type-3 ligand exhibits antidepressant-like activity in preclinical tests (2006) (69)
- High-Throughput FRET Assay Yields Allosteric SERCA Activators (2013) (69)
- Galanin (2–11) binds to GalR3 in transfected cell lines: limitations for pharmacological definition of receptor subtypes (2005) (69)
- Phenotypic analysis of GalR2 knockout mice in anxiety- and depression-related behavioral tests (2008) (68)
- Galanin antisense oligonucleotides reduce galanin levels in dorsal root ganglia and induce autotomy in rats after axotomy. (1994) (68)
- IL-1/IL-1ra balance in the brain revisited – Evidence from transgenic mouse models (2009) (68)
- Interleukin-1β induces hyperpolarization and modulates synaptic inhibition in preoptic and anterior hypothalamic neurons (2006) (68)
- Galanin type 1 receptor knockout mice show altered responses to high-fat diet and glucose challenge (2007) (68)
- IL‐1β induces a MyD88‐dependent and ceramide‐mediated activation of Src in anterior hypothalamic neurons (2006) (67)
- Cutting Edge: IL-13Rα1 Expression in Dopaminergic Neurons Contributes to Their Oxidative Stress–Mediated Loss following Chronic Peripheral Treatment with Lipopolysaccharide (2012) (67)
- Ceramide mediates the rapid phase of febrile response to IL-1beta. (2006) (66)
- Analyzing the validity of GalR1 and GalR2 antibodies using knockout mice (2009) (66)
- Hypothalamic degradation of galanin(1–29) and galanin(1–16): identification and characterization of the peptidolytic products (1991) (64)
- The importance of thiol- and disulfide groups in agonist and antagonist binding to the muscarinic receptor. (1979) (63)
- Galanin inhibits the potassium-evoked release of acetylcholine and the muscarinic receptor-mediated stimulation of phosphoinositide turnover in slices of monkey hippocampus (1991) (63)
- Reversal of Obesity and Insulin Resistance by a Non-Peptidic Glucagon-Like Peptide-1 Receptor Agonist in Diet-Induced Obese Mice (2010) (62)
- Impaired long term memory consolidation in transgenic mice overexpressing the human soluble form of IL-1ra in the brain (2009) (61)
- Sensory neuronal phenotype in galanin receptor 2 knockout mice: focus on dorsal root ganglion neurone development and pain behaviour (2006) (59)
- Night eating and obesity in the EP3R-deficient mouse (2007) (59)
- PNA oligomers as tools for specific modulation of gene expression. (2001) (59)
- Voltage-sensitive calcium channels regulate guanosine 3',5'-cyclic monophosphate levels in neuroblastoma cells. (1978) (59)
- Primary Cell Culture of Live Neurosurgically Resected Aged Adult Human Brain Cells and Single Cell Transcriptomics. (2017) (58)
- IL-6 is essential in TNF-α-induced fever. (1998) (58)
- Blunted neurogenesis and gliosis due to transgenic overexpression of human soluble IL‐1ra in the mouse (2008) (57)
- A Galanin Receptor Subtype 1 Specific Agonist (2005) (56)
- Enhanced hippocampal noradrenaline and serotonin release in galanin-overexpressing mice after repeated forced swimming test (2003) (56)
- Vasoactive intestinal polypeptide and muscarinic receptors: supersensitivity induced by long-term atropine treatment. (1983) (55)
- Interleukin‐1‐like immunoreactiveity in pripheral tissues (1987) (55)
- The brain galanin receptors: targets for novel antidepressant drugs. (2007) (55)
- Galanin overexpressing transgenic mice (2002) (55)
- Distribution and differential regulation of galanin receptor subtypes in rat brain: effects of seizure activity (2005) (55)
- Serotonergic neuron regulation informed by in vivo single‐cell transcriptomics (2014) (54)
- Cyclic nucleotides in the central nervous system. (1978) (54)
- Book Review: Galanin: An Endogenous Anticonvulsant? (2001) (54)
- Immunology: Telling the brain about pain (2001) (52)
- Insights into the roles of the inflammatory mediators IL-1, IL-18 and PGE2 in obesity and insulin resistance. (2008) (51)
- VIP-sensitive adenylate cyclase, guanylate cyclase, muscarinic receptors, choline acetyltransferase and acetylcholinesterase, in brain tissue afflicted by alzheimer's disease/senile dementia of the Alzheimer type (1988) (51)
- Therapeutic potential of new antiinflammatory drugs (2011) (50)
- G protein-coupled receptor 21 deletion improves insulin sensitivity in diet-induced obese mice. (2012) (50)
- Expression of peptides, nitric oxide synthase and NPY receptor in trigeminal and nodose ganglia after nerve lesions (1996) (50)
- Galanin—A neuropeptide with inhibitory actions (1995) (49)
- Interleukin 1 expression is inducible by nerve growth factor in PC12 pheochromocytoma cells. (1991) (49)
- Dopamine release is enhanced while acetylcholine release is inhibited by nimodipine (Bay e 9736). (1986) (48)
- The N-terminal 1-16, but not C-terminal 17-29, galanin fragment affects the flexor reflex in rats. (1990) (48)
- M871—A Novel Peptide Antagonist Selectively Recognizing the Galanin Receptor Type 2 (2006) (48)
- Fluorescence correlation spectroscopy detects galanin receptor diversity on insulinoma cells. (2001) (45)
- Muscarinic acetylcholine receptor from rat brain. Partial purification and characterization. (1976) (45)
- Presynaptic aspects of the coexistence of classical neurotransmitters and peptides (1985) (45)
- Binding and agonist/antagonist actions of M35, galanin(1-13)-bradykinin(2-9) amide chimeric peptide, in Rin m 5F insulinoma cells (1995) (45)
- 8-Br-cyclic GMP mimics activation of muscarinic autoreceptor and inhibits acetylcholine release from rat hippocampal slices (1981) (45)
- Role of galanin receptor 1 and galanin receptor 2 activation in synaptic plasticity associated with 3′,5′-cyclic AMP response element-binding protein phosphorylation in the dentate gyrus: Studies with a galanin receptor 2 agonist and galanin receptor 1 knockout mice (2005) (45)
- Mice over-expressing galanin have elevated heat nociceptive threshold (2001) (44)
- Galanin: neurobiologic mechanisms and therapeutic potential for Alzheimer's disease. (2006) (44)
- Rate equations and simulation curves for enzymatic reactions which utilize lipids as substrates. I. Interaction of enzymes with the monomers and micelles of soluble, amphiphilic lipids. (1977) (44)
- Galanin : basic research discoveries and therapeutic implications (1998) (44)
- Interleukin-1 stimulates the expression of type I and type II interleukin-1 receptors in the rat insulinoma cell line Rinm5F; sequencing a rat type II interleukin-1 receptor cDNA. (1994) (44)
- Galanin message-associated peptide (GMAP)- and galanin-like immunoreactivities: Overlapping and differential distributions in the rat (1992) (44)
- Novel systemically active galanin receptor 2 ligands in depression‐like behavior (2013) (44)
- Delineation of the peptide binding site of the human galanin receptor. (1996) (43)
- New high affinity peptide antagonists to the spinal galanin receptor (1995) (43)
- Acute-phase responses in transgenic mice with CNS overexpression of IL-1 receptor antagonist. (1999) (43)
- A procedure based on statistical criteria for discrimination between steady state kinetic models (1972) (43)
- Galanin, galanin receptors and drug targets. (2008) (43)
- Functional consequences of coexistence of classical and peptide neurotransmitters. (1986) (42)
- Pertussis toxin-sensitive G-protein mediates galanin's inhibition of scopolamine-evoked acetylcholine release in vivo and carbachol-stimulated phosphoinositide turnover in rat ventral hippocampus (1991) (41)
- Renal cytokine responses in acute Escherichia coli pyelonephritis in IL‐6‐deficient mice (2000) (41)
- The Hypothesis Is (2006) (40)
- Intracellular injection of cGMP-dependent protein kinase results in increased input resistance in neurons of the mammalian motor cortex (1986) (40)
- Galanin receptor ligands (2005) (39)
- Hypothalamic and dietary control of temperature-mediated longevity (2010) (39)
- Partial purification and characterization of glyoxalase I from porcine erythrocytes. (1972) (39)
- Co‐localized neuropeptide Y and GABA have complementary presynaptic effects on sensory synaptic transmission (1998) (39)
- Metabolism of galanin and galanin (1–16) in isolated cerebrospinal fluid and spinal cord membranes from rat (1995) (38)
- Presynaptic antagonist-postsynaptic agonist at muscarinic cholinergic synapses. N-methyl-N-(1-methyl-4-pyrrolidino-2-butynyl)acetamide. (1983) (38)
- Novel galanin receptor ligands. (2009) (38)
- Galanin receptors from human pituitary tumors assayed with human galanin as ligand (1993) (37)
- Intrathecal administration of PNA targeting galanin receptor reduces galanin-mediated inhibitory effect in the rat spinal cord (2001) (37)
- Single‐cell transcriptomics and functional target validation of brown adipocytes show their complex roles in metabolic homeostasis (2016) (37)
- Characterization of a neuronal interleukin-1 receptor and the corresponding mRNA in the mouse anterior pituitary cell line AtT-20 (1991) (37)
- Multiple biochemical deficits in both gray and white matter of Alzheimer brains (1986) (36)
- Chronic treatment with the serotonin uptake inhibitor zimelidine elevates substance P levels in rat spinal cord. (1984) (36)
- Enhanced chemokine response in experimental acute Escherichia coli pyelonephritis in IL‐1β‐deficient mice (2003) (36)
- Insulin-like Growth Factor 1-mediated Hyperthermia Involves Anterior Hypothalamic Insulin Receptors* (2011) (36)
- Homodimerization and internalization of galanin type 1 receptor in living CHO cells (2005) (36)
- Cyclic GMP efflux from liver slices. (1983) (36)
- Purification of DT-diaphorase by affinity chromatography. Occurrence of two subunits and nonlinear Dixon and Scatchard plots of the inhibition by anticoagulants. (1976) (36)
- TCF mill trial on softwood pulp with Korsäs thermostable and alkaline stable xylanase T6 (1994) (35)
- Regionally specific induction of ICE mRNA and enzyme activity in the rat brain and adrenal gland by LPS (1996) (35)
- Electrophysiological properties and thermosensitivity of mouse preoptic and anterior hypothalamic neurons in culture (2005) (35)
- Systemic galnon, a low-molecular weight galanin receptor agonist, reduces heat hyperalgesia in rats with nerve injury. (2003) (34)
- cDNA sequence, ligand binding, and regulation of galanin/GMAP in mouse brain (1995) (34)
- Subchronic glucocorticoid pretreatment reversibly attenuates IL-1β induced fever in rats; IL-6 mRNA is elevated while IL-1α and IL-1β mRNAs are suppressed, in the CNS (1996) (34)
- A steady-state kinetic model of butyrylcholinesterase from horse plasma. (1974) (34)
- IL-6 is essential in TNF-alpha-induced fever. (1998) (34)
- Assay for Galanin Receptor (1991) (33)
- Hyperresponsive febrile reactions to interleukin (IL) 1alpha and IL-1beta, and altered brain cytokine mRNA and serum cytokine levels, in IL-1beta-deficient mice. (1997) (33)
- Interleukin-1-mediated febrile responses in mice and interleukin-1 beta activation of NFkappaB in mouse primary astrocytes, involves the interleukin-1 receptor accessory protein. (1998) (33)
- Transgenic overexpression of interleukin-1 receptor antagonist in the CNS influences behaviour, serum corticosterone and brain monoamines (2005) (33)
- Regulation of synthesis of guanosine 3':5'-cyclic monophosphate in neuroblastoma cells. (1978) (32)
- Rate equations and simulation curves for enzymatic reactions which utilize lipids as substrates. II. Effect of adsorption of the substrate or enzyme on the steady-state kinetics. (1977) (32)
- Upregulation of nitric oxide synthase and galanin message-associated peptide in hypothalamic magnocellular neurons after hypophysectomy. Immunohistochemical and in situ hybridization studies (1994) (32)
- Acyl coenzyme A dehydrogenases and electron-transferring flavoprotein from beef hart mitochondria. (1976) (31)
- The steady-state kinetics of glyoxalase I from porcine erythrocytes. Evidence for a random-pathway mechanism involving one- and two-substrate branches. (1973) (31)
- High frequency of TNF alleles -238A and -376A in individuals from northern Sardinia. (2004) (31)
- Galanin-induced inhibition of insulin secretion from rat islets: effects of rat and pig galanin and galanin fragments and analogues. (1991) (31)
- GalR2-positive allosteric modulator exhibits anticonvulsant effects in animal models (2010) (31)
- Presynaptic effects of neuropeptide Y on [3H]noradrenaline and [3H]acetylcholine release (1986) (30)
- Chemistry and Molecular Biology of Galanin Receptor Ligands a (1998) (30)
- Mechanisms of Fever and Febrile Seizures: Putative Role of the Interleukin-1 System (2002) (30)
- Kinetic studies on muscarinic antagonist-agonist competition. (1980) (30)
- Partial purification and characterization of a muscarinic acetylcholine receptor from rat cerebral cortex. (1974) (30)
- Studies on the reaction mechanism of DT diaphorase. Intermediary plateau and trough regions in the initial velocity vs substrate concentration curves. (1975) (30)
- Impairment of memory consolidation by galanin correlates with in vivo inhibition of both LTP and CREB phosphorylation (2009) (30)
- Synthesis of galmic: a nonpeptide galanin receptor agonist. (2004) (30)
- The type I interleukin-1 receptor mediates fever in the rat as shown by interleukin-1 receptor subtype selective ligands (1995) (30)
- Prostaglandin E2-increased thermosensitivity of anterior hypothalamic neurons is associated with depressed inhibition. (2004) (30)
- Protective immunogenicity of two synthetic peptides selected from the amino acid sequence of Bordetella pertussis toxin subunit S1. (1990) (29)
- Metabolic Characterization of a Mouse Deficient in All Known Leptin Receptor Isoforms (2009) (29)
- Galanin Alters GABAergic Neurotransmission in the Dorsal Raphe Nucleus (2008) (29)
- Drug targets: single-cell transcriptomics hastens unbiased discovery. (2012) (29)
- Multiple interaction sites of galnon trigger its biological effects (2005) (29)
- Differential regulation of adenylate cyclase activity in rat ventral and dorsal hippocampus by rat galanin (1995) (29)
- Simultaneous Measurement of Brain and Core Temperature in the Rat during Fever, Hyperthermia, Hypothermia and Sleep (1998) (29)
- N-terminal galanin fragments inhibit the hippocampal release of acetylcholine in vivo (1993) (29)
- Activation of neutral sphingomyelinase by IL-1beta requires the type 1 interleukin 1 receptor. (2000) (28)
- Mutagenesis and ligand modification studies on galanin binding to its GTP-binding-protein-coupled receptor GalR1. (1997) (28)
- Important pharmacophores for binding to galanin receptor 2 (2005) (28)
- Erratum: Interleukin-1β contributes to the generation of experimental febrile seizures (Annals of Neurology (January 2005) 57 (152-155)) (2005) (28)
- Drug Discovery: From Bedside to Wall Street (2005) (28)
- Galanin: an endogenous anticonvulsant? (2001) (28)
- Muscarinic receptors and receptor-mediated actions on rat thymocytes (1988) (28)
- Isolation of a synaptic membrane fraction enriched in cholinergic receptors by controlled phospholipase A2 hydrolysis of synaptic membranes. (1976) (27)
- Galanin receptors and their second messengers in the lumbar dorsal spinal cord. (1992) (27)
- Blockade of galanin-induced inhibition of insulin secretion from isolated mouse islets by the non-methionine containing antagonist M35. (1993) (27)
- Inhibition of striatal muscarinic receptors in vivo by cadmium (1979) (27)
- Neuropeptide Y and peptide YY inhibit adenylate cyclase activity in the rat striatum. (1988) (27)
- Interleukin-1α expression is inducible by cholinergic stimulation in the rat adrenal gland (1992) (27)
- Peripheral axotomy increases the expression of galanin message-associated peptide (GMAP) in dorsal root ganglion cells and alters the effects of intrathecal GMAP on the flexor reflex in the rat (1995) (27)
- Increased hyperalgesia after tissue injury and faster recovery of allodynia after nerve injury in the GalR1 knockout mice (2005) (26)
- Interleukin-1 receptor antagonist protein and mRNA in the rat adrenal gland. (1995) (26)
- NMR study of the conformation and localization of porcine galanin in SDS micelles. Comparison with an inactive analog and a galanin receptor antagonist. (1998) (25)
- Insulin-like growth factor 1 receptor regulates hypothermia during calorie restriction (2017) (25)
- Tachykinin regulation of serotonin release: enhancement of [3H]serotonin release from rat cerebral cortex by neuromedin K and substance P acting at distinct receptor sites (1987) (25)
- Coexistence and interaction of neuropeptides with substance P in primary sensory neurons, with special reference to galanin (1993) (25)
- Chronic atropine treatment causes increase in VIP receptors in rat cerebral cortex (1984) (24)
- Postmortem Changes in Binding to the Muscarinic Receptor from Human Cerebral Cortex (1983) (24)
- Galnon – a low-molecular weight ligand of the galanin receptors (2005) (24)
- Regulation of feeding by galnon (2004) (23)
- Galparan: A Powerful Insulin-Releasing Chimeric Peptide Acting at a Novel Site. (1997) (23)
- Interleukin-1β and tumour necrosis factor-α stimulate the mRNA expression of interleukin-1 receptors in mouse anterior pituitary AtT-20 cells (1995) (23)
- Modes of Peptide Binding in G Protein-Coupled Receptors (1997) (23)
- Adipose tissue as a modulator of clinical inflammation: does obesity reduce the prevalence of rheumatoid arthritis? (2007) (22)
- Effects of Three Galanin Analogs on the Outward Current Evoked by Galanin in Locus Coeruleus a (1998) (22)
- An AP-1 site is involved in the NGF induction of IL-1α in PC12 cells (1996) (22)
- The influence of 8-Br 3′,5′-cyclic nucleotide analogs and of inhibitors of 3′,5′-cyclic nucleotide phosphodiesterase, on noradrenaline secretion and neuromuscular transmission in guinea-pig vas deferens (1979) (21)
- Deletion mutants of human interleukin 1 beta with significantly reduced agonist properties: search for the agonist/antagonist switch in ligands to the interleukin 1 receptors. (1994) (21)
- Molecular characterization of the ligand binding site of the human galanin receptor type 2, identifying subtype selective interactions (2007) (21)
- Conformational analysis of galanin using end to end distance distribution observed by Förster resonance energy transfer (1997) (21)
- G protein-coupled receptor GPR160 is associated with apoptosis and cell cycle arrest of prostate cancer cells (2016) (20)
- THE STRUCTURE AND CONFORMATION OF TRYPTOPHAN IN THE CRYSTAL OF THE PURE RACEMIC COMPOUND AND THE HYDROGEN OXALATE (1981) (20)
- AdipoR1 and 2 are expressed on warm sensitive neurons of the hypothalamic preoptic area and contribute to central hyperthermic effects of adiponectin (2011) (20)
- Cytokine Receptors in the Brain (2008) (20)
- An Inert Proton Coordinated Inside a Nearly Tetrahedral Tetraamine Cavity. Synthesis and X-Ray Crystal Structure of the Aquatrichlorozincate(II) Salt of the Inside Monoprotonated Amine 1,4,8,11-Tetraazatricyclo[6.6.2.2(4,1)]octadecane. (1995) (20)
- Interleukin‐1 in the Noradrenergic Chromaffin Cells in the Rat Adrenal Medulla (1990) (20)
- Discrimination between steady-state kinetic models of the Mechanism of action of yeast glyoxalase I. (1973) (20)
- PHENYLIODINE(III) BIS(TRIFLUOROACETATE) AS A RADICAL CATION GENERATING REAGENT (1995) (19)
- Random pathway mechanism involving parallel one- and two- substrate branches for glyoxalase I from yeast. (1974) (19)
- Downregulation of GPR83 in the hypothalamic preoptic area reduces core body temperature and elevates circulating levels of adiponectin. (2012) (19)
- PREPARATIONS AND TEMPLATE CYCLOTETRAMERISATIONS OF 2,1,3-BENZOTHIA(SELENA)DIAZOLE-5,6-DICARBONITRILES (1995) (19)
- Molecules affecting hypothalamic control of core body temperature in response to calorie intake (2012) (19)
- Increased gene expression of interleukin-1α and interleukin-6 in rat primary glial cells induced by β-amyloid fragment (2001) (18)
- Bidirectional regulation of stress responses by galanin in mice: Involvement of galanin receptor subtype 1 (2009) (18)
- Targeting of antisense PNA oligomers to human galanin receptor type 1 mRNA (2004) (17)
- Acute-phase responses in transgenic mice with CNS overexpression of IL-1 receptor antagonist. (1999) (17)
- Neuro-Immunology of Fever (1992) (17)
- Galanin receptor binding studies in the membranes of cultured cells measured by fluorescence correlation spectroscopy (1999) (17)
- Synthesis, cloning and expression in Escherichia coli of artificial genes coding for biologically active elongated precursors of the vasoactive intestinal polypeptide. (1988) (16)
- Cyclic nucleotides and the nervous system (1982) (16)
- Receptor subtype‐dependent galanin actions on gamma‐aminobutyric acidergic neurotransmission and ethanol responses in the central amygdala (2012) (16)
- Effects of chronic overexpression of interleukin-1 receptor antagonist in a model of permanent focal cerebral ischemia in mouse (2004) (16)
- Solution structure by 2D 1H-NMR of a chimeric peptide recognized by galanin and neuropeptide Y receptors. (1993) (16)
- Somatostatin, substance P, vasoactive intestinal polypeptide, and neuropeptide Y receptors: critical assessment of biochemical methodology and results. (1985) (16)
- Effects of galnon, a non-peptide galanin-receptor agonist, on insulin release from rat pancreatic islets. (2005) (16)
- PROPERTIES OF MIXED-LIGAND CYCLOMETALATED PLATINUM(II) COMPLEXES DERIVED FROM 2-PHENYLPYRIDINE AND 2-(2'-THIENYL)PYRIDINE : VOLTAMMETRIC, ABSORPTION A ND EMISSION STUDIES (1995) (16)
- Prevention by nimodipine, a calcium entry blocker, of the effect of alpha 2-adrenoceptor blocking agents on noradrenaline release: differential effects of nimodipine, on [3H]noradrenaline and [14C]acetylcholine release measured concomitantly from the guinea-pig ileum. (1986) (14)
- Biochemical studies on muscarinic receptors (1981) (14)
- Regulation of ICE activity and ICE isoforms by LPS (1997) (14)
- MODELS OF REGULATION OF NOREPINEPHRINE SECRETION BY PREJUNCTIONAL RECEPTORS AND BY FACILITATION: ROLE OF CALCIUM AND CYCLIC NUCLEOTIDES (1979) (14)
- REACTION OF CHIRAL LITHIUM HETERO(BUTYL)CUPRATES WITH 2-CYCLOHEXENONE AND 4-PHENYL-3-BUTEN-2-ONE (1981) (14)
- Rotational Barriers and the Number of Stereoisomers of Iodixanol, an X-Ray Contrast Agent. (1995) (14)
- Serotonergic potentiation of muscarinic agonist evoked tremor and salivation in rat and mouse (2004) (14)
- Galanin stimulates the N-methyl-d-aspartate receptor/nitric oxide/cyclic GMP pathway in vivo in the rat ventral hippocampus (1998) (14)
- Mutagenesis Study on Human Galanin Receptor GalR1 Reveals Domains Involved in Ligand Binding a (1998) (14)
- INTERLEUKIN 1 (IL-1) TYPE I RECEPTORS MEDIATE ACTIVATION OF RAT HYPOTHALAMUS–PITUITARY–ADRENAL AXIS AND INTERLEUKIN 6 PRODUCTION AS SHOWN BY RECEPTOR TYPE SELECTIVE DELETION MUTANTS OF IL-1β (1998) (14)
- Thermochemical and Structural Investigations on the Systems NaCl/TbCl3 and NaCl/DyCl3. (1995) (13)
- Pharma TARP: A Troubled Asset Relief Program for Novel, Abandoned Projects in the Pharmaceutical Industry (2011) (13)
- N-Terminally elongated fragments of galanin(1–16) inhibit insulin secretion from isolated mouse islets (1994) (13)
- The Future of Drug Discovery: Who Decides Which Diseases to Treat? (2013) (13)
- Muscarinic Stimulation and cGMP Synthesis in the Nervous System (1978) (13)
- Subchronic glucocorticoid pretreatment reversibly attenuates IL-beta induced fever in rats; IL-6 mRNA is elevated while IL-1 alpha and IL-1 beta mRNAs are suppressed, in the CNS. (1996) (13)
- Serotonin type-2 receptor mediated regulation of substance P release in the ventral spinal cord and the effects of chronic antidepressant treatment (1986) (13)
- Galanin – 25 years with a multitalented neuropeptide (2008) (13)
- Hypersensitive cytokine response to beta-amyloid 25-35 in astroglial cells from IL-1 receptor type I-deficient mice. (1998) (13)
- Binding of [3H]-pilocarpine to membranes from rat cerebral cortex (1981) (12)
- Use of synthetic peptides to map antigenic sites of Bordetella pertussis toxin subunit S1. (1988) (12)
- Increased gene expression of interleukin-1alpha and interleukin-6 in rat primary glial cells induced by beta-amyloid fragment. (2001) (12)
- Functional effects and ligand binding of chimeric galanin‐neuropeptide Y (NPY) peptides on NPY and galanin receptor types (1994) (12)
- Galanin/GALP receptors and CNS homeostatic processes. (2006) (12)
- Effect of galnon on induction of long-term potentiation in dentate gyrus of C57BL/6 mice (2005) (12)
- Immunohistochemical demonstration of galanin‐, and galanin message‐associated peptide‐like immunoreactivities in sympathetic ganglia and adrenal gland of the guinea pig (1994) (12)
- Mechanism of the galanin induced increase in acetylcholine release in vivo from striata of freely moving rats (1992) (12)
- The effects of intrathecal galanin message-associated peptide (GMAP) on the flexor reflex in rats (1995) (11)
- Synthesis of cell-penetrating peptide-PNA constructs. (2002) (11)
- L-Ala-substituted rat galanin analogs distinguish between hypothalamic and jejunal galanin receptor subtypes. (2009) (11)
- Morphological and behavioral changes induced by transgenic overexpression of interleukin‐1ra in the brain (2011) (11)
- Chemical Neuroanatomy of the Hypothalamo-Pituitary Axis: Focus on Multimessenger Systems (1987) (11)
- Acute and chronic studies on functional aspects of coexistence. (1988) (11)
- Biological activities of two endogenously occurring N-terminally extended forms of galanin in the rat spinal cord. (1994) (11)
- Fragments of galanin message-associated peptide (GMAP) modulate the spinal flexor reflex in rat. (1996) (10)
- Ccl22/MDC, is a prostaglandin dependent pyrogen, acting in the anterior hypothalamus to induce hyperthermia via activation of brown adipose tissue. (2011) (10)
- In vitro and in vivo inhibition of [3H]imipramine binding by cadmium. (1983) (10)
- On the Ionic Mechanism of Presynaptic Muscarinic Receptor Action in Rat Hippocampus (1981) (10)
- Anticholinergic potency of psychoactive drugs in human and rat cerebral cortex and striatum. (1985) (10)
- GALANIN RECEPTOR LIGANDS AS POTENTIAL THERAPEUTIC AGENTS IN DEPRESSION AND NEURODEGENERATION (1995) (10)
- Functional aspects of acetylcholine-galanin coexistence in the brain. (1990) (10)
- Molecular mechanisms of fever (1998) (10)
- Discrimination between mathematical models of biological systems exemplified by enzyme steady state kinetics. (1973) (10)
- Novel isoforms of the TFIID subunit TAF4 modulate nuclear receptor-mediated transcriptional activity. (2004) (10)
- Galparan: a powerful insulin-releasing chimeric peptide acting at a novel site. (1997) (10)
- TLR2 is Required for the Altered Transcription of p75NGF Receptors in Gram Positive Infection (2006) (9)
- Rat thymocytes release a factor which inhibits muscarinic ligand binding (1988) (9)
- TRANSITION STATES IN THE CRYSTALLINE PHASE ? THERMAL REARRANGEMENTS OF SOLID 4H-1,2,4-TRIAZOLES (1995) (9)
- OLIGOMERIZATION OF ETHYLENE WITH CATIONIC PHENANTHROLINE(METHYL)PALLADIUM COMPLEXES (1995) (9)
- Solvent stabilized solution structures of galanin and galanin analogs, studied by circular dichroism spectroscopy. (1995) (9)
- Positive allosteric modulators to peptide GPCRs: a promising class of drugs (2013) (8)
- Two ligands may bind simultaneously to the muscarine receptor (1982) (8)
- Synthesis and biological evaluation of novel pyrimidine derivatives as sub-micromolar affinity ligands of GalR2. (2011) (8)
- Effect of whooping-cough vaccine on cyclic-GMP levels in the brain (1979) (8)
- Guanylate cyclase activity increases after kainic acid lesion of rat striatum (1979) (8)
- Substance P and neurokinin A, two coexisting tachykinins stimulating the release of [3H]5-HT from rat cerebral cortical slices (1990) (8)
- Iodinated derivatives of the vasoactive intestinal polypeptide (VIP) are agonists at the cat pancreas and the rat submandibular salivary gland (1986) (8)
- On the solution structure of galanin (1991) (8)
- Age-related impairments of synaptic plasticity in the lateral perforant path input to the dentate gyrus of galanin overexpressing mice (2005) (8)
- Characterization of the N-terminal structure of pertussis toxin subunit S1 and hybridization of oligodeoxyribonucleotide probes with a Bordetella pertussis DNA fragment (1986) (8)
- Pharmacogenomics in drug development: societal and technical aspects (2004) (8)
- Substance P receptors in the rat spinal cord: the effect of GTP and of chronic antidepressant treatment. (1988) (8)
- Human/mouse interleukin‐1 receptor/receptor accessory protein interactions in IL‐1β‐induced NFκB activation (1998) (7)
- Conformations and Rotational Barriers in NADH and NAD+ Analogues. A Dynamic NMR and Molecular Mechanics Investigation. (1995) (7)
- Fever (2010) (7)
- Analogs of galanin (1-16) modified in positions 1-3 as ligands to rat hypothalamic galanin receptors. (1994) (7)
- The effect of naturally occurring fragments of galanin message-associated peptide on spinal cord excitability in rats (1997) (7)
- Chronic Exposure to Pertussis Toxin Alters Muscarinic Receptor‐Mediated Regulation of Cyclic AMP Metabolism in Neuroblastoma × Glioma NG108–15 Hybrid Cells (1988) (7)
- In vivo andin vitro studies on the potentiation of muscarinic receptor stimulation by alaproclate, a selective 5-HT uptake blocker (2005) (7)
- In Vivo and in Vitro Studies on a Muscarinic Presynaptic Antagonist and Postsynaptic Agonist: BM-5 (1986) (7)
- Muscarinic Acetylcholine Receptors (1988) (7)
- TWENTY QUESTIONS: THE STATE OF GPCR RESEARCH IN 2004 (2004) (7)
- THE MECHANISM OF RUO4-MEDIATED OXIDATIONS OF ETHERS: ISOTOPE EFFECTS, SOLVENT EFFECTS AND SUBSTITUENT EFFECTS (1995) (7)
- Molecular Genetic Approaches to the Neuropharmacology of Corticotropin-Releasing Factor (2001) (7)
- Galparan induces in vivo acetylcholine release in the frontal cortex (1997) (7)
- THERMODYNAMIC ACIDITIES AND HOMOLYTIC METAL-HYDROGEN BOND ENERGIES OF GROUP 8 PROTONATED DECAMETHYLMETALLOCENES CP*2MH+(M=RU, OS) (1995) (6)
- Midlife interventions are critical in prevention, delay, or improvement of Alzheimer’s disease and vascular cognitive impairment and dementia (2017) (6)
- Atropine treatment induced cholinergic supersensitivity at receptor and second messenger levels in the rat salivary gland. (1990) (6)
- Agonist--antagonist--muscarinic receptor ternary complex. (1980) (6)
- Interleukin-1 alpha expression is inducible by cholinergic stimulation in the rat adrenal gland. (1992) (6)
- An AP-1 site is involved in the NGF induction of IL-1 alpha in PC12 cells. (1996) (6)
- Orthovanadate induces loss of muscarinic cholinergic binding sites. (1983) (6)
- Muscarinic antagonist binding to intact rat thymocytes. (1990) (6)
- Interaction of drugs with the cyclic nucleotide generating enzymes in the central nervous system (1984) (5)
- Purification of a galanin degrading 70 kDa metallo-peptidase from bovine spinal cord (1998) (5)
- GEA 857, a putative blocker of potassium conductance, enhances muscarinic agonist-evoked responses: dissociation from an action on 5-HT mechanisms. (1992) (5)
- Central and sensory galanin neurons and functional aspects (1992) (5)
- In vivo and in vitro studies of inhibitory effects of restorative dental materials on salivary esterases. (1980) (5)
- Galanin receptors as novel drug targets for the treatment of depression and anxiety (2005) (5)
- Galanin receptor ligands in the hippocampus: Galanin, N-terminal galanin fragments and analogs (1991) (5)
- On the Absence of 2-(2'-Cyclopentenyl)glycine-Derived Cyanogenic Glycosides in Cassava, Manihot esculenta Crantz. (1995) (5)
- The structure of the rodent and porcine neuropeptide galanin and antagonists as determined by FTIR and CD spectroscopy (1994) (5)
- Cell Surface Protein mRNAs Show Differential Transcription in Pyramidal and Fast-Spiking Cells as Revealed by Single-Cell Sequencing. (2020) (4)
- POTENTIAL GABA UPTAKE INHIBITORS. SYNTHESIS AND RELATIVE STEREOCHEMISTRY OF SOME AMINOPIPERIDINECARBOXYLIC ACIDS (1980) (4)
- Effects of chloride ion substitution on the frequency dependence and alpha-autoinhibition of [3H]noradrenaline secretion in guinea-pig vas deferens. (1986) (4)
- Uncoupler-accelerated efflux of 5-hydroxytryptamine from platelets of healthy subjects and patients with unipolar and bipolar depression (1984) (4)
- Binding of [ 3 H ]-Piloearpine to Membranes from Rat Cerebral Cortex (4)
- Interleukin-1 beta and tumour necrosis factor-alpha stimulate the mRNA expression of interleukin-1 receptors in mouse anterior pituitary AtT-20 cells. (1995) (4)
- Photochemical Nitration by Tetranitromethane. Part XXIV. Adduct Formation in the Photochemical Reaction of 1,4,6,7-Tetramethylnaphthalene; Some Rearrangement Studies of 1,4,6,7-Tetramethyl-r-1-nitro-t-4-trinitromethyl-1,4-dihydronaphthalene and Evidence for Inverted Spin Trapping of Trinitromethanid (1995) (4)
- A sensitive method for measuring neutralizing antibodies to Bordetella pertussis toxin: optimized ADP-ribosylation of transducin. (1991) (4)
- COMPLEXATION AND DECOMPOSITION OF BENZENEDIAZONIUM TETRAFLUOROBORATE IN THE PRESENCE OF ACYCLIC POLYETHERS IN 1,2-DICHLOROETHANE AND IN THE GAS PHASE (1995) (4)
- Human/mouse interleukin-1 receptor/receptor accessory protein interactions in IL-1beta-induced NFkappaB activation. (1998) (4)
- Target-Based Drug Discovery (2006) (4)
- Application of weight factors in the discrimination between mathematical models of enzyme kinetics (1973) (3)
- Identification of the spinal degradation products and inhibition of adenylate cyclase by recombinant rat galanin message-associated peptide (1998) (3)
- Galanin message-associated polypeptide (GMAP) does not affect insulin secretion from isolated islets. (1994) (3)
- Galanin: Receptor subtypes, agonists and antagonists. Chemistry and pharmacology (1994) (3)
- Why is the New York Times Writing so Much about Alzheimer's Disease Therapies? (2010) (3)
- Possible correlation between noradrenergic innervation in the cerebellum and jumping behavior in mice (1980) (3)
- Synthesis of an N-methyldehydroalanine-containing fragment of microcystin by combination of solid phase peptide synthesis and beta-elimination in solution. (1995) (3)
- On the Mechanism of the Deprotonation of Alkylbenzene Cation Radicals in Acetonitrile. (1980) (3)
- COLOCALIZATION OF NEUROPEPTIDES AND CLASSICAL NEUROTRANSMITTERS ‐ FUNCTIONAL SIGNIFICANCE (1992) (3)
- PREPARATION OF TWO AGGRESSION CONTROLLING SUBSTANCES IN BEES (1995) (3)
- Neurobiological Mechanisms of Fever (1998) (3)
- Galanin in the cholinergic basal forebrain: histochemical, autoradiographic and in vivo studies. (1989) (3)
- IS THE ALPHA-ADRENOCEPTOR MEDIATED INHIBITION OF NORADRENALINE SECRETION A NEGATIVE FEEDBACK CONTROL IN THE STRICT SENSE? (1981) (2)
- Interleukin 1 (IL-1) type I receptors mediate activation of rat hypothalamus-pituitary-adrenal axis and interleukin 6 production as shown by receptor type selective deletion mutants of IL-1beta. (1998) (2)
- STRUCTURAL STUDIES OF A PARTICULATE X-RAY CONTRAST AGENT : A MULTI-METHOD APPROACH (1995) (2)
- It all happens between Toll receptors and Caspase 1 (2007) (2)
- The importance of hydrophobic interactions in the antagonist binding to the muscarinic acetylcholine receptor. (1982) (2)
- Increased affinity of choline acetyltransferase for choline in Alzheimer's disease: a steady-state kinetic study (1987) (2)
- X-Ray Crystallographic Study of Tetrammine-Carbonatocobalt(III) Sulfate Trihydrate, [Co(NH3)4CO3]2SO4.3H2O. (1995) (2)
- Which diseases do we want to treat (2013) (2)
- From Lab Bench to Wall Street (2006) (2)
- Peptides as active probes. (1995) (2)
- Why is pharma a special industry (2013) (2)
- Galanin regulation of acetylcholine release and carbachol-stimulated phosphoinositide turnover in rat ventral hippocampus (1991) (2)
- LINKS BETWEEN THE THEORETICAL RATE LAW AND THE EXPERIMENTAL RESPONSE SURFACE : AN EXAMPLE WITH A SOLVOLYSIS REACTION (1995) (2)
- Alzheimer Drug Trials: Combination of Safe and Efficacious Biologicals to Break the Amyloidosis-Neuroinflammation Vicious Cycle (2020) (2)
- ON THE QUESTION OF THE INTERMEDIATE FORMATION OF CARBENE ANION RADICALS DURING CATHODIC REDUCTION OF 9-DIAZOFLUORENE (1981) (2)
- Erratum: Night eating and obesity in the EP3R-deficient mouse (Proceedings of the National Academy of Sciences of the United States of America (2007) 104, 8, (3009-3014) DIO: 10.1073/pnas.0611209104) (2007) (2)
- Therapeutic areas (2013) (2)
- Vasoactive Intestinal Polypeptide-Muscarinic Cholinergic Interactions (1986) (2)
- Phosphorylation of Membrane Proteins in Excitable Cells and Changes in Membrane Properties Experimental Paradigms and Interpretations, a Biochemist’s View (1986) (1)
- KINETIC STUDIES OF THE SULFONATION OF 2-TERT-BUTYLPHENOL WITH CHLOROSULFONIC ACID (1981) (1)
- Modeling drug discovery until 2025 (2013) (1)
- Neuropeptides and Neuropeptide Receptors: Drug Targets, and Peptide and Non-Peptide Ligands: A Tribute to Prof. Dieter Seebach (2013) (1)
- Interactions of Coexisting Neurotransmitters and Effects of Chronic Drug Treatment (1987) (1)
- STUDIES OF N-ACYL-2-PYRIDINECARBOXANILIDES. PREPARATION BY VARIOUS REACTION SEQUENCES AND REACTION WITH HYDROGEN CHLORIDE TO GIVE ACYL IMIDATE HYDROCHLORIDES THROUGH AN INTRAMOLECULAR N → O ACYL MIGRATION (1980) (1)
- A Note on the Methyl Inductive Effect in Sulfides. (1978) (1)
- Potential role for the plague as a selective force in Sardinia (2007) (1)
- Coexistence and interaction of neuropeptides with substance P and other tachykinins, with special reference to galanin (1992) (1)
- Determination of thermodynamic constants for agonist binding to muscarinic receptors from rat cerebral cortex. (1987) (1)
- The future of drug discovery (2017) (1)
- Galanin message associated peptide (1992) (1)
- Toll-like receptors as pharmacological targets (2006) (1)
- The need for medicines grows (2013) (1)
- Cool by neuronal decision (2016) (1)
- A blood based 12-miRNA signature of Alzheimer disease patients (2013) (1)
- Immunological and binding studies on chloroform--methanol extracts from electroplax of Torpedo marmorata and from rat brain cortex. Comparison of the material solubilized by organic solvents with the receptor proteins solubilized by detergents. (1978) (1)
- What's the Most Profitable Approach? (2006) (0)
- The Better Beta-Blocker Barrier (2006) (0)
- Human 5/RANTES and by Lipopolysaccharide in Activated by the CC Chemokine Ligand Analysis of the Gene Expression Profile (2002) (0)
- Linking Putative Targets to Disease States (2006) (0)
- Medicines are becoming better: some of the breakthrough medicines of the past decades (2013) (0)
- Diagnosing toward personalized medicine (2013) (0)
- Uncoupling protein 2 expression in hypothalamus of rodents during fever and in different metabolic conditions (2000) (0)
- K. Mitsukawa, X. Lu, and T. Bartfai (2010) (0)
- INFLUENCE OF TEMPERATURE ON COOPERATIVE BINDING OF N-METHYLPIPERIDINYLBENZILATE WITH MUSCARINIC RECEPTOR FROM RAT CEREBRAL CORTEX (1987) (0)
- N-methyl-N'-nitro-N-nitrosoguanidine and cyclic GMP stimulate phosphorylation of nuclear proteins from rat liver. (1986) (0)
- Pertussis toxin-sensitive G-proteins mediate galanin receptor regulation of Pre- and postsynaptic cholinergic functions in ventral hippocampus (1992) (0)
- More Ways to Look for Targets (2006) (0)
- Raising and Rising Expectations (2006) (0)
- Neuropeptide-receptor interactions: With special reference to the VIP receptor(s) (1989) (0)
- Molecular mechanism of muscarinic auto inhibition of acetyl choline and vasoactive intestinal poly peptide release (1983) (0)
- More Tablets Taken per Day than Meals Served (2006) (0)
- Chapter 09 – Personalized medicine (2013) (0)
- Galanin receptor ligands: agonists and antagonists (1992) (0)
- Development of VIP-Receptor supersensitivity in the periphery and CNS upon chronic atropine treatment (1983) (0)
- Assessing Company Assets? Look in the Library (2006) (0)
- Adding Value in a Growth Industry (2006) (0)
- Febrile Response and Seizures (2019) (0)
- Hyperresponsive febrile reactions to interleukin (IL) 1 (cid:97) and IL-1 (cid:98) , and altered brain cytokine mRNA and serum cytokine levels, in IL-1 (cid:98) -deficient mice (1997) (0)
- Working with the Food and Drug Administration (FDA) (2006) (0)
- Choices in neuroscience careers (2008) (0)
- Shrinking Value of Targets (2006) (0)
- Acknowledgement of Reviewers (2005) (0)
- Peptide receptors: Anything different from targeting amine systems? (2002) (0)
- The Art of Putting a Molecule into Man (2006) (0)
- Regulating Regulatory Regimens Reliably (2006) (0)
- Drug development models between 2010 & 2025 (2013) (0)
- Contributors to Volume 5 (1991) (0)
- So Many Drugs, So Few Entities (2006) (0)
- Changes Need to Be Made (2006) (0)
- Pharmacoeconomics for Biotech (2006) (0)
- Why Some Good Drugs Do Not Get a Chance and Why Others Fail (2006) (0)
- Molecular and Integrative Neurosciences (2006) (0)
- Tribulations for clinical trials. (1991) (0)
- Synthetic galanin analogs with biochemical activity (1991) (0)
- Device for determining and / or monitoring the level of a medium (2006) (0)
- Thermotolerance, Thermoresistance, and Thermosensitivity (2007) (0)
- Azide reversibly raises cyclic GMP levels in hepatic slices and activates guanylate cyclase. (1980) (0)
- Welcome to Drug Discovery Today: Disease Mechanisms (2004) (0)
- How to Find a Candidate Drug (2006) (0)
- To Merge or Not to Merge (2006) (0)
- History Is Good to Know (2006) (0)
- Preface (1998) (0)
- Radiolabeling and characterization of binding sites for the galanin receptor antagonist M35 (1992) (0)
- What Are “We” All Working On? (2006) (0)
- Reactions between Furyl Ketones and Grignard Reagents. III. Suppression of 1,4-Addition of Benzylmagnesium Chloride to Alkyl 2-Furyl Ketones by Voluminous Alkyl Groups at the Carbonyl Carbon. (1980) (0)
- Neuropeptide Receptors – Drug Development (2009) (0)
- Simultaneous synthesis and cloning of artificial genes coding for analogs of VIP and their expression in E. Coli (1989) (0)
- Practical Trials for a Balanced Portfolio (2006) (0)
- Human Monocytes 5/RANTES and by Lipopolysaccharide in Activated by the CC Chemokine Ligand Analysis of the Gene Expression Profile (2002) (0)
- High frequency of TNF alleles-238A and -376A in Sardinia (2003) (0)
- Protective immunogenicity of synthetic peptides selected from the amino acid sequence of Bordetella pertussis toxin subunit S1. (1991) (0)
- Synthesis of Cell-Penetrating Peptide-PNA Constructs (2003) (0)
- BM-5, a centrally active partial muscarinic agonist with low tremorogenic activity (1987) (0)
- Why there will be new drugs despite the ongoing “crisis” of drug development in Big Pharma (2013) (0)
- Chapter 00: Introduction (2013) (0)
- Table of Contents (1996) (0)
- Proceedings: Rate equations and simulation curves for enzymatic reactions utilizing lipids as substrates. (1975) (0)
- [Alzheimer's disease, growth disorders, pain... Galanin--a new peptide in front line research. Interview by Bigit Wilhelmson]. (1992) (0)
- How much can drugs cost (2013) (0)
- Future prospects in muscarinic cholinergic pharmacology. Outstanding problems and promises. (1990) (0)
- Blockbuster proprietary drugs versus generic drugs (2013) (0)
- Chapter 05 Therapeutic areas Strategically important diseases of the future (2013) (0)
- Clinical outcome for patients with traumatic brain injury correlates with the quota between the anti-inflammatory 1L-1ra and the pro-inflammatory 1L-6 in Liqvor (1998) (0)
- Interleukin1 increases the expression of its receptors (IL-1R) in a rat β-pancreatic cell line (Rinm5F) (1994) (0)
- About the Economics of Target and Clinical Candidate Selection (2006) (0)
- The Business Basics (General) (2006) (0)
- Coexistence of Neuroactive Substances in Neurons edited by Victoria Chan-Palay and Sanford L. Palay, John Wiley and Sons, 1984. £85.45 (xvii + 433 pages) ISBN 0 471 89503 2 (1985) (0)
- Molecular and Integrative Medicine (2008) (0)
- How to Improve the Odds of Finding a Safe Drug That Works (2006) (0)
- Acknowledgements to Reviewers (2004) (0)
- 89 – CYCLIC GMP LEVELS IN NEUROBLASTOMA CELLS ARE INCREASED BY DEPOLARIZATION AND BY MUSCARINIC RECEPTOR ACTIVATION (1978) (0)
- Reviewer Acknowledgments (2009) (0)
- P.1.12 Functional role of galanin and its receptors in hippocampal synaptic plasticity: Electrophysiological studies on transgenic mice (2004) (0)
- Advances in cyclic nucleotide research volume 15 (1984) (0)
- Corrigendum to “Effects of galnon, a non-peptide galanin-receptor agonist, on insulin release from rat pancreatic islets” [Biochem. Biophys. Res. Commun. 328 (2005) 213–220] (2008) (0)
- Acknowledgement to Reviewers (2002) (0)
- Interleukin-1EnhancesNMDAReceptor-Mediated IntracellularCalciumIncreasethroughActivationoftheSrc FamilyofKinases (2003) (0)
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