Ted Murray Dawson
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Biology
Ted Murray Dawson's Degrees
- PhD Neuroscience Stanford University
- Bachelors Biology University of California, Berkeley
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(Suggest an Edit or Addition)Ted Murray Dawson's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Neurotoxic reactive astrocytes are induced by activated microglia (2017) (4001)
- Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 (2018) (3106)
- Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (2012) (2913)
- Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012 (2011) (2295)
- Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures. (1991) (2225)
- Nitric oxide synthase and neuronal NADPH diaphorase are identical in brain and peripheral tissues. (1991) (1833)
- Mediation of Poly(ADP-Ribose) Polymerase-1-Dependent Cell Death by Apoptosis-Inducing Factor (2002) (1803)
- Molecular Pathways of Neurodegeneration in Parkinson's Disease (2003) (1629)
- PINK1-dependent recruitment of Parkin to mitochondria in mitophagy (2009) (1449)
- Nitric oxide synthase protein and mRNA are discretely localized in neuronal populations of the mammalian CNS together with NADPH diaphorase (1991) (1389)
- Targeted disruption of the neuronal nitric oxide synthase gene (1993) (1319)
- Molecular pathophysiology of Parkinson's disease. (2005) (1213)
- Nitric oxide activation of poly(ADP-ribose) synthetase in neurotoxicity. (1994) (1156)
- Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity. (2005) (1122)
- Interference by Huntingtin and Atrophin-1 with CBP-Mediated Transcription Leading to Cellular Toxicity (2001) (1122)
- Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia (1997) (1040)
- Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson disease (1999) (1018)
- Parkin functions as an E2-dependent ubiquitin- protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1. (2000) (959)
- A novel neuronal messenger molecule in brain: The free radical, nitric oxide (1992) (840)
- PARIS (ZNF746) Repression of PGC-1α Contributes to Neurodegeneration in Parkinson's Disease (2011) (824)
- Essential versus accessory aspects of cell death: recommendations of the NCCD 2015 (2014) (799)
- Genetic Animal Models of Parkinson's Disease (2010) (746)
- Parkin ubiquitinates the α-synuclein–interacting protein, synphilin-1: implications for Lewy-body formation in Parkinson disease (2001) (733)
- Nitric oxide synthase generates superoxide and nitric oxide in arginine-depleted cells leading to peroxynitrite-mediated cellular injury. (1996) (726)
- Apoptosis-inducing factor mediates poly(ADP-ribose) (PAR) polymer-induced cell death (2006) (690)
- Human α-synuclein-harboring familial Parkinson's disease-linked Ala-53 → Thr mutation causes neurodegenerative disease with α-synuclein aggregation in transgenic mice (2002) (672)
- Nitric oxide synthase in models of focal ischemia. (1997) (671)
- Endothelial nitric oxide synthase localized to hippocampal pyramidal cells: implications for synaptic plasticity. (1994) (659)
- S-Nitrosylation of Parkin Regulates Ubiquitination and Compromises Parkin's Protective Function (2004) (652)
- CHIP and Hsp70 regulate tau ubiquitination, degradation and aggregation (2004) (652)
- Kinase activity of mutant LRRK2 mediates neuronal toxicity (2006) (650)
- Diagnosis and treatment of Parkinson disease: molecules to medicine. (2006) (611)
- Role of neuronal nitric oxide in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity. (1996) (610)
- Behavioural abnormalities in male mice lacking neuronal nitric oxide synthase (1995) (597)
- Induction of nitric oxide synthase in demyelinating regions of multiple sclerosis brains (1994) (585)
- Poly(ADP-ribose) (PAR) polymer is a death signal (2006) (582)
- Parkinson's disease-associated mutations in LRRK2 link enhanced GTP-binding and kinase activities to neuronal toxicity. (2007) (569)
- Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson’s disease (2018) (547)
- Widespread expression of Huntington's disease gene (IT15) protein product (1995) (545)
- Immunosuppressant FK506 enhances phosphorylation of nitric oxide synthase and protects against glutamate neurotoxicity. (1993) (539)
- Parkin Mediates Nonclassical, Proteasomal-Independent Ubiquitination of Synphilin-1: Implications for Lewy Body Formation (2005) (530)
- Localization of LRRK2 to membranous and vesicular structures in mammalian brain (2006) (530)
- Beta-arrestin2, a novel member of the arrestin/beta-arrestin gene family. (1992) (516)
- Nitric oxide synthase in cardiac sarcoplasmic reticulum. (1999) (509)
- Apoptosis-inducing factor is involved in the regulation of caspase-independent neuronal cell death (2002) (501)
- Inducible expression of mutant alpha-synuclein decreases proteasome activity and increases sensitivity to mitochondria-dependent apoptosis. (2001) (500)
- Nitric oxide neurotoxicity (1996) (488)
- DJ-1 gene deletion reveals that DJ-1 is an atypical peroxiredoxin-like peroxidase (2007) (470)
- Pathological α-synuclein transmission initiated by binding lymphocyte-activation gene 3 (2016) (463)
- Pharmacological Rescue of Mitochondrial Deficits in iPSC-Derived Neural Cells from Patients with Familial Parkinson’s Disease (2012) (461)
- Nuclear and mitochondrial conversations in cell death: PARP-1 and AIF signaling. (2004) (460)
- Leucine-rich repeat kinase 2 (LRRK2) interacts with parkin, and mutant LRRK2 induces neuronal degeneration. (2005) (459)
- T cells from patients with Parkinson’s disease recognize α-synuclein peptides (2017) (442)
- Mitochondrial localization of the Parkinson's disease related protein DJ-1: implications for pathogenesis. (2005) (440)
- Synphilin-1 associates with α-synuclein and promotes the formation of cytosolic inclusions (1999) (438)
- Lysine 63-linked ubiquitination promotes the formation and autophagic clearance of protein inclusions associated with neurodegenerative diseases. (2008) (432)
- Immunologic NO Synthase: Elevation in Severe AIDS Dementia and Induction by HIV-1 gp41 (1996) (431)
- Endothelial NOS and the blockade of LTP by NOS inhibitors in mice lacking neuronal NOS. (1994) (431)
- Aggregation promoting C-terminal truncation of alpha-synuclein is a normal cellular process and is enhanced by the familial Parkinson's disease-linked mutations. (2005) (419)
- Oxidative Stress and Genetics in the Pathogenesis of Parkinson's Disease (2000) (411)
- Parthanatos: mitochondrial‐linked mechanisms and therapeutic opportunities (2014) (391)
- Truncated N-terminal fragments of huntingtin with expanded glutamine repeats form nuclear and cytoplasmic aggregates in cell culture. (1998) (390)
- Dopaminergic Neuronal Loss, Reduced Neurite Complexity and Autophagic Abnormalities in Transgenic Mice Expressing G2019S Mutant LRRK2 (2011) (384)
- Possible Origins and Distribution of Immunoreactive Nitric Oxide Synthase-Containing Nerve Fibers in Cerebral Arteries (1993) (381)
- Nitric oxide in neurodegeneration. (1998) (380)
- Recent advances in the genetics of Parkinson's disease. (2011) (378)
- Nitric oxide-induced nuclear GAPDH activates p300/CBP and mediates apoptosis (2008) (370)
- Poly(ADP-ribose) polymerase activation mediates 1-methyl-4-phenyl-1, 2,3,6-tetrahydropyridine (MPTP)-induced parkinsonism. (1999) (368)
- Proteome-wide identification of poly(ADP-ribose) binding proteins and poly(ADP-ribose)-associated protein complexes (2008) (365)
- Human alpha-synuclein-harboring familial Parkinson's disease-linked Ala-53 --> Thr mutation causes neurodegenerative disease with alpha-synuclein aggregation in transgenic mice. (2002) (357)
- Poly(ADP-Ribose) (PAR) Binding to Apoptosis-Inducing Factor Is Critical for PAR Polymerase-1–Dependent Cell Death (Parthanatos) (2011) (354)
- Endoplasmic reticulum stress and mitochondrial cell death pathways mediate A53T mutant alpha-synuclein-induced toxicity. (2005) (354)
- High brain densities of the immunophilin FKBP colocalized with calcineurin (1992) (346)
- Parthanatos, a messenger of death. (2009) (342)
- Human immunodeficiency virus type 1 coat protein neurotoxicity mediated by nitric oxide in primary cortical cultures. (1993) (342)
- Poly(ADP-ribose) signals to mitochondrial AIF: A key event in parthanatos (2009) (337)
- D-1 dopamine receptors in the rat brain: a quantitative autoradiographic analysis (1986) (336)
- Neurotrophic actions of nonimmunosuppressive analogues of immunosuppressive drugs FK506, rapamycin and cyclosporin A (1997) (334)
- Parkin‐independent mitophagy requires Drp1 and maintains the integrity of mammalian heart and brain (2014) (333)
- Loss of locus coeruleus neurons and reduced startle in parkin null mice. (2004) (330)
- Requirement for nitric oxide activation of p21(ras)/extracellular regulated kinase in neuronal ischemic preconditioning. (2000) (329)
- Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 (2018) (323)
- Parkin and PINK1: much more than mitophagy (2014) (321)
- The role of parkin in familial and sporadic Parkinson's disease (2010) (319)
- Treatment of early Parkinson's disease (2000) (309)
- Failure to degrade poly(ADP-ribose) causes increased sensitivity to cytotoxicity and early embryonic lethality. (2004) (308)
- A randomized clinical trial of high-dosage coenzyme Q10 in early Parkinson disease: no evidence of benefit. (2014) (294)
- Neurobiology of nitric oxide. (1996) (292)
- Apoptosis-Inducing Factor Substitutes for Caspase Executioners in NMDA-Triggered Excitotoxic Neuronal Death (2004) (287)
- Nitric oxide in health and disease of the nervous system (1997) (287)
- Meta‐analysis of Parkinson's Disease: Identification of a novel locus, RIT2 (2012) (274)
- Immunosuppressant FK506 promotes neurite outgrowth in cultures of PC12 cells and sensory ganglia. (1994) (273)
- Manganese Superoxide Dismutase Protects nNOS Neurons from NMDA and Nitric Oxide-Mediated Neurotoxicity (1998) (270)
- Ataxia Telangiectasia Mutated (ATM) Signaling Network Is Modulated by a Novel Poly(ADP-ribose)-dependent Pathway in the Early Response to DNA-damaging Agents* (2007) (266)
- Free Radicals as Mediators of Neuronal Injury (1998) (263)
- Expression of inducible nitric oxide synthase causes delayed neurotoxicity in primary mixed neuronal-glial cortical cultures (1994) (262)
- Understanding microRNAs in neurodegeneration (2009) (256)
- PARP‐1 gene disruption in mice preferentially protects males from perinatal brain injury (2004) (254)
- Mediation of cell death by poly(ADP-ribose) polymerase-1. (2005) (251)
- Association of DJ-1 and parkin mediated by pathogenic DJ-1 mutations and oxidative stress. (2005) (246)
- Phosphorylation by the c-Abl protein tyrosine kinase inhibits parkin's ubiquitination and protective function (2010) (245)
- Nitric oxide mediates the formation of synaptic connections in developing and regenerating olfactory receptor neurons (1994) (244)
- Rat spinal cord neurons contain nitric oxide synthase (1994) (244)
- Accumulation of the Authentic Parkin Substrate Aminoacyl-tRNA Synthetase Cofactor, p38/JTV-1, Leads to Catecholaminergic Cell Death (2005) (238)
- Caught in the Act α-Synuclein Is the Culprit in Parkinson's Disease (2003) (238)
- Animal models of neurodegenerative diseases (2018) (238)
- A Hierarchical NGF Signaling Cascade Controls Ret-Dependent and Ret-Independent Events during Development of Nonpeptidergic DRG Neurons (2007) (237)
- Synphilin-1 associates with alpha-synuclein and promotes the formation of cytosolic inclusions. (1999) (235)
- Poly(ADP-ribose) polymerase-dependent energy depletion occurs through inhibition of glycolysis (2014) (235)
- Neuroprotection by pharmacologic blockade of the GAPDH death cascade. (2006) (234)
- Rare genetic mutations shed light on the pathogenesis of Parkinson disease. (2003) (231)
- MicroRNA-223 is neuroprotective by targeting glutamate receptors (2012) (227)
- A missense mutation (L166P) in DJ‐1, linked to familial Parkinson's disease, confers reduced protein stability and impairs homo‐oligomerization (2003) (226)
- Mitochondrial and Nuclear Cross Talk in Cell Death (2008) (226)
- Sulfhydration mediates neuroprotective actions of parkin (2013) (226)
- A randomized, double-blind, futility clinical trial of creatine and minocycline in early Parkinson disease (2006) (224)
- Poly(ADP-ribose) drives pathologic α-synuclein neurodegeneration in Parkinson’s disease (2018) (222)
- The role of the ubiquitin-proteasomal pathway in Parkinson's disease and other neurodegenerative disorders (2001) (220)
- α-Synuclein Phosphorylation Enhances Eosinophilic Cytoplasmic Inclusion Formation in SH-SY5Y Cells (2005) (219)
- A nitric oxide signaling pathway controls CREB-mediated gene expression in neurons. (2006) (219)
- Ribosomal Protein s15 Phosphorylation Mediates LRRK2 Neurodegeneration in Parkinson’s Disease (2014) (219)
- NMDA But Not Non-NMDA Excitotoxicity is Mediated by Poly(ADP-Ribose) Polymerase (2000) (218)
- Familial-associated mutations differentially disrupt the solubility, localization, binding and ubiquitination properties of parkin. (2005) (218)
- Nitric Oxide-Dependent Penile Erection in Mice Lacking Neuronal Nitric Oxide Synthase (1996) (217)
- A nuclease that mediates cell death induced by DNA damage and poly(ADP-ribose) polymerase-1 (2016) (215)
- Parkin Protects against LRRK2 G2019S Mutant-Induced Dopaminergic Neurodegeneration in Drosophila (2009) (213)
- Nuclear Targeting of Mutant Huntingtin Increases Toxicity (1999) (210)
- Brain serotonin dysfunction accounts for aggression in male mice lacking neuronal nitric oxide synthase. (2001) (210)
- Stress-induced alterations in parkin solubility promote parkin aggregation and compromise parkin's protective function. (2005) (209)
- Deadly Conversations: Nuclear-Mitochondrial Cross-Talk (2004) (202)
- T cells of Parkinson’s disease patients recognize α–synuclein peptides (2017) (200)
- Iduna is a poly(ADP-ribose) (PAR)-dependent E3 ubiquitin ligase that regulates DNA damage (2011) (200)
- Neuronal (type I) nitric oxide synthase regulates nuclear factor kappaB activity and immunologic (type II) nitric oxide synthase expression. (1997) (198)
- GTPase Activity Plays a Key Role in the Pathobiology of LRRK2 (2010) (196)
- Poly(ADP-ribose) polymerase-1 and apoptosis inducing factor in neurotoxicity (2003) (196)
- Nitric oxide mediates N-methyl-D-aspartate receptor-induced activation of p21ras. (1998) (194)
- Beta-adrenergic receptor kinase-2 and beta-arrestin-2 as mediators of odorant-induced desensitization. (1993) (194)
- CHIP regulates leucine-rich repeat kinase-2 ubiquitination, degradation, and toxicity (2009) (191)
- The Chaperone Activity of Heat Shock Protein 90 Is Critical for Maintaining the Stability of Leucine-Rich Repeat Kinase 2 (2008) (190)
- Aβ deposition is associated with enhanced cortical α-synuclein lesions in Lewy body diseases (2005) (187)
- The c-Abl inhibitor, Nilotinib, protects dopaminergic neurons in a preclinical animal model of Parkinson's disease (2014) (185)
- Parkin loss leads to PARIS-dependent declines in mitochondrial mass and respiration (2015) (182)
- Relative sparing of nitric oxide synthase–containing neurons in the hippocampal formation in Alzheimer's disease (1992) (181)
- Critical role for nitric oxide signaling in cardiac and neuronal ischemic preconditioning and tolerance. (2001) (180)
- Dynamic regulation of neuronal NO synthase transcription by calcium influx through a CREB family transcription factor-dependent mechanism. (2000) (178)
- PINK1 and Parkin mitochondrial quality control: a source of regional vulnerability in Parkinson’s disease (2020) (177)
- Parthanatos Mediates AIMP2 Activated Age Dependent Dopaminergic Neuronal Loss (2013) (177)
- NITRIC OXIDE ACTIONS IN NEUROCHEMISTRY (1996) (177)
- Psychiatric comorbidities in patients with Parkinson disease and psychosis (2004) (172)
- Association of GBA Mutations and the E326K Polymorphism With Motor and Cognitive Progression in Parkinson Disease. (2016) (172)
- Localization of Parkinson’s disease-associated LRRK2 in normal and pathological human brain (2007) (167)
- Inhibitors of Leucine Rich Repeat Kinase 2 (LRRK2) Protect Against LRRK2-Models of Parkinson’s Disease (2010) (163)
- Autophagy-mediated clearance of aggresomes is not a universal phenomenon. (2008) (163)
- Neuroprotective and neurorestorative strategies for Parkinson's disease (2002) (162)
- Dynamic and redundant regulation of LRRK2 and LRRK1 expression (2007) (159)
- Comparison of the distribution of D-1 and D-2 dopamine receptors in the rat brain. (1989) (159)
- GBA Variants are associated with a distinct pattern of cognitive deficits in Parkinson's disease (2016) (157)
- Novel Monoclonal Antibodies Demonstrate Biochemical Variation of Brain Parkin with Age* (2003) (155)
- Morphometry of the human substantia nigra in ageing and Parkinson’s disease (2008) (152)
- Nitric oxide synthase: role as a transmitter/mediator in the brain and endocrine system. (1996) (151)
- Msp1/ATAD1 maintains mitochondrial function by facilitating the degradation of mislocalized tail‐anchored proteins (2014) (150)
- Expansion of polyglutamine repeat in huntingtin leads to abnormal protein interactions involving calmodulin. (1996) (150)
- Loss of nitric oxide synthase immunoreactivity in cerebral vasospasm. (1996) (148)
- The D1 dopamine receptor in the rat brain: Quantitative autoradiographic localization using an iodinated ligand (1988) (147)
- Cyclic nucleotide dependent phosphorylation of neuronal nitric oxide synthase inhibits catalytic activity (1994) (146)
- S-nitrosylation of XIAP compromises neuronal survival in Parkinson's disease (2009) (146)
- The immunophilins, FK506 binding protein and cyclophilin, are discretely localized in the brain: relationship to calcineurin (1994) (146)
- Reprogramming cellular events by poly(ADP-ribose)-binding proteins (2012) (145)
- Opportunities for the repurposing of PARP inhibitors for the therapy of non‐oncological diseases (2018) (145)
- Animal Models of PD Pieces of the Same Puzzle? (2002) (145)
- Parkin-mediated lysine 63-linked polyubiquitination: A link to protein inclusions formation in Parkinson's and other conformational diseases? (2006) (144)
- Nitric Oxide in Neuronal Degeneration (1996) (143)
- Mitochondrial Stasis Reveals p62-Mediated Ubiquitination in Parkin-Independent Mitophagy and Mitigates Nonalcoholic Fatty Liver Disease. (2018) (142)
- D-1 dopamine receptors in the rat brain: autoradiographic localization using [3H]SCH 23390. (1985) (142)
- Bcl-x Is Required for Proper Development of the Mouse Substantia Nigra (2005) (141)
- Iduna protects the brain from glutamate excitotoxicity and stroke by interfering with poly(ADP-ribose) polymer-induced cell death (2011) (141)
- Meta-Analysis of the Alzheimer’s Disease Human Brain Transcriptome and Functional Dissection in Mouse Models (2020) (140)
- Urinary bladder-urethral sphincter dysfunction in mice with targeted disruption of neuronal nitric oxide synthase models idiopathic voiding disorders in humans (1997) (139)
- LRRK2 pathobiology in Parkinson's disease (2014) (136)
- What causes cell death in Parkinson's disease? (2008) (134)
- Unexpected Lack of Hypersensitivity in LRRK2 Knock-Out Mice to MPTP (1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine) (2009) (133)
- Parkin-associated Parkinson’s disease (2004) (133)
- Huntingtin-associated protein (HAP1): discrete neuronal localizations in the brain resemble those of neuronal nitric oxide synthase. (1996) (133)
- Development and Characterization of a New Parkinson's Disease Model Resulting from Impaired Autophagy (2012) (132)
- Interaction between neuronal nitric oxide synthase and inhibitory G protein activity in heart rate regulation in conscious mice. (1998) (130)
- GBA1 deficiency negatively affects physiological α-synuclein tetramers and related multimers (2018) (130)
- Cerebrovascular alterations in mice lacking neuronal nitric oxide synthase gene expression. (1995) (129)
- Chemoproteomics-based design of potent LRRK2-selective lead compounds that attenuate Parkinson's disease-related toxicity in human neurons. (2011) (129)
- PINK1 Primes Parkin-Mediated Ubiquitination of PARIS in Dopaminergic Neuronal Survival. (2017) (128)
- SEPT5_v2 is a parkin-binding protein. (2003) (128)
- (Patho‐)physiological relevance of PINK1‐dependent ubiquitin phosphorylation (2015) (128)
- Inhibitors of LRRK2 kinase attenuate neurodegeneration and Parkinson-like phenotypes in Caenorhabditis elegans and Drosophila Parkinson's disease models. (2011) (127)
- Creation of an Open-Access, Mutation-Defined Fibroblast Resource for Neurological Disease Research (2012) (126)
- Apoptosis Inducing Factor and PARP‐Mediated Injury in the MPTP Mouse Model of Parkinson's Disease (2003) (126)
- Fyn kinase regulates misfolded α-synuclein uptake and NLRP3 inflammasome activation in microglia (2019) (125)
- Toward the human cellular microRNAome (2017) (125)
- Regulation of neuronal nitric oxide synthase and identification of novel nitric oxide signaling pathways. (1998) (123)
- Mechanism of neurodegenerative disease: role of the ubiquitin proteasome system (2004) (122)
- Poly(ADP-Ribose) Polymerase Impairs Early and Long-Term Experimental Stroke Recovery (2002) (122)
- mdx muscle pathology is independent of nNOS perturbation. (1998) (121)
- FKBP12, the 12-kDa FK506-binding protein, is a physiologic regulator of the cell cycle (2001) (121)
- Genetic deficiency of the mitochondrial protein PGAM5 causes a Parkinson’s-like movement disorder (2014) (120)
- Alterations in the solubility and intracellular localization of parkin by several familial Parkinson's disease‐linked point mutations (2005) (120)
- 37-kDa Laminin Receptor Precursor Modulates Cytotoxic Necrotizing Factor 1–mediated RhoA Activation and Bacterial Uptake* (2003) (120)
- Molecular Mechanisms of Nitric Oxide Actions in the Brain a (1994) (119)
- Expression and localization of Parkinson's disease‐associated leucine‐rich repeat kinase 2 in the mouse brain (2007) (119)
- Neurotransmitter release regulated by nitric oxide in PC-12 cells and brain synaptosomes (1993) (118)
- Functional interaction of Parkinson's disease-associated LRRK2 with members of the dynamin GTPase superfamily (2013) (118)
- Abeta deposition is associated with enhanced cortical alpha-synuclein lesions in Lewy body diseases. (2005) (116)
- Animal models of Parkinson's disease: vertebrate genetics. (2012) (115)
- Microglia and astrocyte dysfunction in parkinson's disease (2020) (115)
- New Animal Models for Parkinson's Disease (2000) (115)
- Heterozygous PINK1 p.G411S increases risk of Parkinson’s disease via a dominant-negative mechanism (2016) (114)
- Activation of tyrosine kinase c-Abl contributes to α-synuclein-induced neurodegeneration. (2016) (112)
- Identification of Far Upstream Element-binding Protein-1 as an Authentic Parkin Substrate* (2006) (111)
- Alpha-synuclein phosphorylation enhances eosinophilic cytoplasmic inclusion formation in SH-SY5Y cells. (2005) (110)
- NMDA-R1 subunit of the cerebral cortex co-localizes with neuronal nitric oxide synthase at pre- and postsynaptic sites and in spines (1997) (110)
- Effects of Nitric Oxide on Neuroendocrine Function and Behavior (1997) (109)
- Free radicals and neuronal cell death. (1996) (109)
- Role of nitric oxide in Parkinson's disease. (2006) (105)
- To die or grow: Parkinson's disease and cancer (2005) (104)
- Mitochondrial Mechanisms of Neuronal Cell Death: Potential Therapeutics. (2017) (104)
- Inhibition of Neuronal Nitric Oxide Synthase Increases Aggressive Behavior in Mice (1997) (103)
- BAK alters neuronal excitability and can switch from anti- to pro-death function during postnatal development. (2003) (101)
- Parkin mediates the degradation‐independent ubiquitination of Hsp70 (2008) (101)
- Cell Death Mechanisms of Neurodegeneration. (2017) (100)
- Journal Club: Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia (1998) (100)
- ArfGAP1 Is a GTPase Activating Protein for LRRK2: Reciprocal Regulation of ArfGAP1 by LRRK2 (2012) (100)
- Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture (2021) (99)
- Differential Susceptibility to Neurotoxicity Mediated by Neurotrophins and Neuronal Nitric Oxide Synthase (1997) (99)
- MicroRNA-132 dysregulation in Toxoplasma gondii infection has implications for dopamine signaling pathway (2014) (97)
- Finding useful biomarkers for Parkinson’s disease (2018) (96)
- Calpain activation is not required for AIF translocation in PARP‐1‐dependent cell death (parthanatos) (2009) (95)
- Neuroimmunophilin ligands exert neuroregeneration and neuroprotection in midbrain dopaminergic neurons (2001) (94)
- Rate and Severity of HIV-Associated Dementia (HAD): Correlations with Gp41 and iNOS (1999) (94)
- Lack of involvement of neuronal nitric oxide synthase in the pathogenesis of a transgenic mouse model of familial amyotrophic lateral sclerosis (1999) (92)
- Genetic modifiers of risk and age at onset in GBA associated Parkinson's disease and Lewy body dementia. (2019) (92)
- Relative Sensitivity of Parkin and Other Cysteine-containing Enzymes to Stress-induced Solubility Alterations* (2007) (92)
- REVIEW ■ : Nitric Oxide: Actions and Pathological Roles (1995) (92)
- Nuclear Localization of a Non-caspase Truncation Product of Atrophin-1, with an Expanded Polyglutamine Repeat, Increases Cellular Toxicity* (2003) (89)
- Presynaptic and postsynaptic D1 dopamine receptors in the nigrostriatal system of the rat brain: a quantitative autoradiographic study using the selective D1 antagonist [3H]SCH 23390 (1987) (89)
- Nocturnal motor coordination deficits in neuronal nitric oxide synthase knock-out mice (1999) (88)
- EndoG is dispensable in embryogenesis and apoptosis (2006) (88)
- Receptor alterations associated with serotonergic agents: an autoradiographic analysis. (1987) (86)
- TRPV1 on astrocytes rescues nigral dopamine neurons in Parkinson's disease via CNTF. (2015) (85)
- Physiological and toxicological actions of nitric oxide in the central nervous system. (1995) (84)
- Nitric oxide: cellular regulation and neuronal injury. (1994) (84)
- Lysine 63-linked polyubiquitin potentially partners with p62 to promote the clearance of protein inclusions by autophagy (2008) (84)
- Inclusion Body Formation and Neurodegeneration Are Parkin Independent in a Mouse Model of α-Synucleinopathy (2006) (84)
- Evidence for dopamine D-2 receptors on cholinergic interneurons in the rat caudate-putamen. (1988) (83)
- Conditional transgenic mice expressing C-terminally truncated human α-synuclein (αSyn119) exhibit reduced striatal dopamine without loss of nigrostriatal pathway dopaminergic neurons (2009) (83)
- Sex differences in progression to mild cognitive impairment and dementia in Parkinson's disease. (2018) (82)
- Abnormal Localization of Leucine-Rich Repeat Kinase 2 to the Endosomal-Lysosomal Compartment in Lewy Body Disease (2009) (82)
- Neurovirulent Simian Immunodeficiency Virus Infection Induces Neuronal, Endothelial, and Glial Apoptosis (1996) (82)
- Nitric oxide synthase (NOS) in schizophrenia: increases in cerebellar vermis. (1996) (80)
- Neuroimmunophilins: Novel neuroprotective and neuroregenerative targets (2001) (80)
- Alpha‐synuclein and Parkinson's disease: Implications from the screening of more than 1,900 patients (2005) (79)
- Absence of inclusion body formation in the MPTP mouse model of Parkinson's disease. (2005) (79)
- A novel in vivo post‐translational modification of p53 by PARP‐1 in MPTP‐induced parkinsonism (2002) (79)
- Dopamine D-2 auto- and postsynaptic receptors in the nigrostriatal system of the rat brain: localization by quantitative autoradiography with [3H]sulpiride. (1987) (78)
- NMDAR1 Glutamate Receptor Subunit Isoforms in Neostriatal, Neocortical, and Hippocampal Nitric Oxide Synthase Neurons (1998) (78)
- Localization of nigrostriatal dopamine receptor subtypes and adenylate cyclase (1988) (78)
- Quantitative autoradiography of [3H]forskolin binding sites in the rat brain (1985) (76)
- Dysregulated phosphorylation of Rab GTPases by LRRK2 induces neurodegeneration (2018) (76)
- Functional recovery of supersensitive dopamine receptors after intrastriatal grafts of fetal substantia nigra (1991) (75)
- ADP-ribosyltransferases, an update on function and nomenclature (2021) (74)
- Neurodegenerative phenotypes in an A53T α-synuclein transgenic mouse model are independent of LRRK2. (2012) (74)
- Parkin and defective ubiquitination in Parkinson's disease. (2006) (74)
- Adult Conditional Knockout of PGC-1α Leads to Loss of Dopamine Neurons (2016) (74)
- Enhanced Autophagy from Chronic Toxicity of Iron and Mutant A53T α-Synuclein (2011) (73)
- Parkin Plays a Role in Sporadic Parkinson's Disease (2013) (73)
- The AAA+ ATPase Thorase Regulates AMPA Receptor-Dependent Synaptic Plasticity and Behavior (2011) (73)
- Outer mitochondrial membrane localization of apoptosis-inducing factor: mechanistic implications for release (2009) (72)
- The NINDS Parkinson's disease biomarkers program (2016) (72)
- Neuroprotective effects of gangliosides may involve inhibition of nitric oxide synthase (1995) (71)
- Synphilin-1 attenuates neuronal degeneration in the A53T alpha-synuclein transgenic mouse model. (2010) (70)
- Response to Comment on "S-Nitrosylation of Parkin Regulates Ubiquitination and Compromises Parkin's Protective Function" (2005) (69)
- Nitric oxide, S-nitrosylation and neurodegeneration. (2005) (69)
- Mechanisms and Structural Determinants of HIV-1 Coat Protein, gp41-Induced Neurotoxicity (1999) (69)
- MPTP and DSP-4 susceptibility of substantia nigra and locus coeruleus catecholaminergic neurons in mice is independent of parkin activity (2007) (68)
- Leucine-rich repeat kinase 2 (LRRK2) as a potential therapeutic target in Parkinson's disease. (2012) (68)
- α-Synuclein accumulation and GBA deficiency due to L444P GBA mutation contributes to MPTP-induced parkinsonism (2018) (68)
- The role of nitric oxide in Parkinson's disease. (2001) (67)
- SQSTM1/p62 promotes mitochondrial ubiquitination independently of PINK1 and PRKN/parkin in mitophagy (2019) (67)
- Immunophilin Regulation of Neurotransmitter Release (1996) (66)
- Efficacy of Nilotinib in Patients With Moderately Advanced Parkinson Disease (2020) (66)
- LRRK2 Affects Vesicle Trafficking, Neurotransmitter Extracellular Level and Membrane Receptor Localization (2013) (64)
- Neurotoxicity and behavioral deficits associated with Septin 5 accumulation in dopaminergic neurons (2005) (64)
- Identification and analysis of plasticity-induced late-response genes (2004) (64)
- Resistance to MPTP-Neurotoxicity in α-Synuclein Knockout Mice Is Complemented by Human α-Synuclein and Associated with Increased β-Synuclein and Akt Activation (2011) (64)
- MicroRNAs in Parkinson's disease (2011) (63)
- Poly(ADP-ribosyl)ation regulation of life and death in the nervous system. (2005) (63)
- Preconditioning-mediated neuroprotection through erythropoietin? (2002) (62)
- Caught in the act: alpha-synuclein is the culprit in Parkinson's disease. (2003) (62)
- Neuroprotective FK506 does not alter in vivo nitric oxide production during ischemia and early reperfusion in rats. (1999) (61)
- c-Abl and Parkinson’s Disease: Mechanisms and Therapeutic Potential (2017) (61)
- Neuronal NOS and cyclooxygenase-2 contribute to DNA damage in a mouse model of Parkinson disease. (2009) (61)
- Inhibitors of LRRK 2 kinase attenuate neurodegeneration and Parkinson-like phenotypes in Caenorhabditis elegans and Drosophila Parkinson ’ s disease models (2011) (61)
- Cultured networks of excitatory projection neurons and inhibitory interneurons for studying human cortical neurotoxicity (2016) (60)
- New insights into Parkinson’s disease (2003) (60)
- Aggressive behavior in male mice lacking the gene for neuronal nitric oxide synthase requires testosterone (1997) (59)
- Protein Microarray Characterization of the S-Nitrosoproteome* (2013) (58)
- Neuronal ischaemic preconditioning. (2000) (58)
- CREB family transcription factors inhibit neuronal suicide (2002) (57)
- Next-generation sequencing reveals substantial genetic contribution to dementia with Lewy bodies (2016) (57)
- Cortical interneurons become activated by deafferentation and instruct the apoptosis of pyramidal neurons. (2004) (56)
- Conditional expression of Parkinson's disease-related R1441C LRRK2 in midbrain dopaminergic neurons of mice causes nuclear abnormalities without neurodegeneration (2014) (56)
- Robust kinase- and age-dependent dopaminergic and norepinephrine neurodegeneration in LRRK2 G2019S transgenic mice (2018) (56)
- Quantitative autoradiographic localization of D-1 dopamine receptors in the rat brain: Use of the iodinated ligand [125I]SCH 23982 (1986) (56)
- Trumping neurodegeneration: Targeting common pathways regulated by autosomal recessive Parkinson's disease genes (2017) (55)
- Cognitive profile of LRRK2‐related Parkinson's disease (2015) (55)
- Nitric Oxide Signaling in Neurodegeneration and Cell Death. (2018) (55)
- The PINK1 p.I368N mutation affects protein stability and ubiquitin kinase activity (2017) (54)
- The Roles of Kinases in Familial Parkinson's Disease (2007) (54)
- Parkinson's disease genetic mutations increase cell susceptibility to stress: Mutant α-synuclein enhances H2O2- and Sin-1-induced cell death (2007) (54)
- Role for the ubiquitin-proteasome system in Parkinson’s disease and other neurodegenerative brain amyloidoses (2007) (54)
- Contributions of poly(ADP‐ribose) polymerase‐1 and ‐2 to nuclear translocation of apoptosis‐inducing factor and injury from focal cerebral ischemia (2010) (53)
- The A1 astrocyte paradigm: New avenues for pharmacological intervention in neurodegeneration (2019) (53)
- Neuronal Activity Regulates Hippocampal miRNA Expression (2011) (53)
- Reevaluation of Phosphorylation Sites in the Parkinson Disease-associated Leucine-rich Repeat Kinase 2* (2010) (53)
- Pathological Endogenous α-Synuclein Accumulation in Oligodendrocyte Precursor Cells Potentially Induces Inclusions in Multiple System Atrophy (2018) (51)
- Inositol 1,4,5-trisphosphate receptors: Immunohistochemical localization to discrete areas of rat central nervous system (1993) (51)
- Faculty Opinions recommendation of A molecular pathway of neurodegeneration linking alpha-synuclein to ApoE and Abeta peptides. (2008) (50)
- The interplay of microRNA and neuronal activity in health and disease (2013) (50)
- Stroke Outcome in Double-Mutant Antioxidant Transgenic Mice (2000) (50)
- Botch promotes neurogenesis by antagonizing Notch. (2012) (49)
- Enhanced expression of nitric oxide synthase by rat retina following pterygopalatine parasympathetic denervation (1993) (48)
- PARK10 is a major locus for sporadic neuropathologically confirmed Parkinson disease (2015) (48)
- NMDA-induced neuronal survival is mediated through nuclear factor I-A in mice. (2010) (47)
- Genetic modifiers of risk and age at onset in GBA associated Parkinson’s disease and Lewy body dementia (2019) (47)
- Nitric Oxide Protects Cardiac Sarcolemmal Membrane Enzyme Function and Ion Active Transport against Ischemia-induced Inactivation* (2003) (46)
- Molecular Neurodegeneration (2017) (45)
- Ubiqutination via K27 and K29 chains signals aggregation and neuronal protection of LRRK2 by WSB1 (2016) (45)
- A homozygous ATAD1 mutation impairs postsynaptic AMPA receptor trafficking and causes a lethal encephalopathy (2018) (45)
- Mitochondrial voltage-dependent anion channel. Immunochemical and immunohistochemical characterization in rat brain. (1993) (45)
- Value of genetic models in understanding the cause and mechanisms of Parkinson’s disease (2008) (44)
- Parkin Blushed by PINK1 (2006) (44)
- The cell biology of Parkinson's disease. (2021) (44)
- Methamphetamine-induced reduction in D1 and D2 dopamine receptors as evidenced by autoradiography: Comparison with tyrosine hydroxylase activity (1987) (43)
- PARIS induced defects in mitochondrial biogenesis drive dopamine neuron loss under conditions of parkin or PINK1 deficiency (2020) (43)
- Inhibitors of leucine-rich repeat kinase-2 protect against models of Parkinson's disease. (2016) (43)
- The Cast of Molecular Characters in Parkinson's Disease (2003) (43)
- Glial pathology and retinal neurotoxicity in the anterior visual pathway in experimental autoimmune encephalomyelitis (2019) (42)
- Influence of duration of focal cerebral ischemia and neuronal nitric oxide synthase on translocation of apoptosis-inducing factor to the nucleus (2007) (41)
- Effects of Central Inhibition of Nitric Oxide Synthase on Focal Cerebral Ischemia in Rats (1995) (41)
- Quantitative autoradiographic localization of the dopamine transport complex in the rat brain: use of a highly selective radioligand: [3H]GBR 12935. (1986) (40)
- Models of LRRK2-Associated Parkinson's Disease. (2017) (40)
- Muscarinic and dopaminergic receptor subtypes on striatal cholinergic interneurons (1990) (40)
- Lack of nitric oxide synthase depresses ion transporting enzyme function in cardiac muscle. (2002) (40)
- Blocking microglial activation of reactive astrocytes is neuroprotective in models of Alzheimer’s disease (2021) (40)
- Determinants of seeding and spreading of α-synuclein pathology in the brain (2020) (39)
- Parkinson's disease biomarkers: perspective from the NINDS Parkinson's Disease Biomarkers Program. (2017) (39)
- Early-onset Parkinson's disease due to PINK1 p.Q456X mutation--clinical and functional study. (2014) (39)
- Synaptic Plasticity onto Dopamine Neurons Shapes Fear Learning (2017) (39)
- Activation mechanisms of the E3 ubiquitin ligase parkin. (2017) (39)
- Nanozyme scavenging ROS for prevention of pathologic α-synuclein transmission in Parkinson’s disease (2021) (39)
- Poly (ADP-ribose) (PAR)-dependent cell death in neurodegenerative diseases. (2020) (39)
- Linked Clinical Trials – The Development of New Clinical Learning Studies in Parkinson’s Disease Using Screening of Multiple Prospective New Treatments (2013) (39)
- Spatial and functional relationship between poly(ADP-ribose) polymerase-1 and poly(ADP-ribose) glycohydrolase in the brain (2007) (38)
- Autoradiographic localization of [3H]-imipramine binding sites: Association with serotonergic neurons (1983) (38)
- Precision therapy for a new disorder of AMPA receptor recycling due to mutations in ATAD1 (2017) (38)
- S-nitrosylation in Parkinson's disease and related neurodegenerative disorders. (2005) (37)
- Nigral dopamine type-1 receptors are reduced in Huntington's disease: A postmortem autoradiographic study using [3H]SCH 23390 and correlation with [3H]forskolin binding (1990) (36)
- Proneural Transcription Factor Atoh1 Drives Highly Efficient Differentiation of Human Pluripotent Stem Cells Into Dopaminergic Neurons (2014) (36)
- Ganglioside Regulation of AMPA Receptor Trafficking (2014) (36)
- Circadian Locomotor Analysis of Male Mice Lacking the Gene for Neuronal Nitric Oxide Synthase (nNOS–/–) (1999) (35)
- Parkin functions as an E3-dependent ubiquitin-protein ligase and promotes the degradation of synaptic vesicle associated protein (2000) (35)
- Advances in neuronal cell death 2007. (2008) (35)
- Transcriptional responses to loss or gain of function of the leucine-rich repeat kinase 2 (LRRK2) gene uncover biological processes modulated by LRRK2 activity. (2012) (35)
- LRRK2 G2019S transgenic mice display increased susceptibility to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-mediated neurotoxicity (2016) (34)
- Nitric oxide as a mediator of neurotoxicity. (1993) (34)
- Parkin interacting substrate zinc finger protein 746 is a pathological mediator in Parkinson's disease. (2019) (34)
- Synthetic mRNAs Drive Highly Efficient iPS Cell Differentiation to Dopaminergic Neurons (2018) (34)
- Autoradiographic Evidence of [3H]SCH 23390 Binding Site; in Human Prefrontal Cortex (Brodmann's Area 9) (1987) (34)
- Mechanistic basis for receptor-mediated pathological α-synuclein fibril cell-to-cell transmission in Parkinson's disease (2021) (34)
- Identification of calcium- and nitric oxide-regulated genes by differential analysis of library expression (DAzLE). (2004) (34)
- Dopamine transporter availability reflects gastrointestinal dysautonomia in early Parkinson disease. (2018) (34)
- New synaptic and molecular targets for neuroprotection in Parkinson's disease (2013) (33)
- DISC1 regulates lactate metabolism in astrocytes: implications for psychiatric disorders (2018) (33)
- The impact of genetic research on our understanding of Parkinson's disease. (2010) (33)
- Promising disease-modifying therapies for Parkinson’s disease (2019) (33)
- Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356 (2016) (33)
- The orphan nuclear receptor, steroidogenic factor 1, regulates neuronal nitric oxide synthase gene expression in pituitary gonadotropes. (2002) (32)
- Glutamate-stimulated calcium activation of Ras/Erk pathway mediated by nitric oxide. (1999) (32)
- Lessons from Drosophila models of DJ-1 deficiency. (2006) (32)
- Identification through high‐throughput screening of 4'‐methoxyflavone and 3',4'‐dimethoxyflavone as novel neuroprotective inhibitors of parthanatos (2013) (31)
- Quantitative autoradiographic evidence for axonal transport of imipramine receptors in the central nervous system of the rat (1985) (31)
- Impaired Ovulation in Mice with Targeted Deletion of the Neuronal Isoform of Nitric Oxide Synthase (1998) (30)
- The involvement of nitric oxide in the enhanced expression of μ‐opioid receptors during intestinal inflammation in mice (2005) (30)
- Functional Identification of Neuroprotective Molecules (2010) (29)
- Leucine-Rich Repeat Kinase 2 Expression Leads to Aggresome Formation That Is Not Associated With &agr;-Synuclein Inclusions (2009) (29)
- Defects in Mitochondrial Biogenesis Drive Mitochondrial Alterations in PARKIN-Deficient Human Dopamine Neurons (2020) (29)
- Motor Neuron Death in ALS: Programmed by Astrocytes? (2014) (28)
- Botch is a γ-glutamyl cyclotransferase that deglycinates and antagonizes Notch. (2014) (28)
- Overexpression of Parkinson’s Disease-Associated Mutation LRRK2 G2019S in Mouse Forebrain Induces Behavioral Deficits and α-Synuclein Pathology (2017) (28)
- Chronic administration of sertraline, a selective serotonin uptake inhibitor, decreased the density of β-adrenergic receptors in rat frontoparietal cortex (1987) (28)
- Evidence that [3H]forskolin binding in the substantia nigra is intrinsic to a striatal-nigral projection: An autoradiographic study of rat brain (1987) (27)
- Neurodegenerative disorders and gut-brain interactions. (2021) (27)
- Quantitative autoradiographic localization of central dopamine D-1 and D-2 receptors. (1986) (26)
- gp120 neurotoxicity in primary cortical cultures. (1994) (25)
- Nitric Oxide: Diverse Actions in the Central and Peripheral Nervous Systems (1998) (25)
- Downregulation of muscarinic receptors in the rat caudate-putamen after lesioning of the ipsilateral nigrostriatal dopamine pathway with 6-hydroxydopamine (6-OHDA): normalization by fetal mesencephalic transplants (1991) (25)
- STING mediates neurodegeneration and neuroinflammation in nigrostriatal α-synucleinopathy (2022) (25)
- Parkin and Hsp70 Sacked by BAG5 (2004) (25)
- Erratum: T cells from patients with Parkinson’s disease recognize α-synuclein peptides (2017) (25)
- Heritability and genetic variance of dementia with Lewy bodies (2018) (25)
- Absence of C9ORF72 expanded or intermediate repeats in autopsy‐confirmed Parkinson's disease (2014) (25)
- The Road to Survival Goes through PARG (2005) (24)
- Defects in mRNA Translation in LRRK2-Mutant hiPSC-Derived Dopaminergic Neurons Lead to Dysregulated Calcium Homeostasis. (2020) (24)
- MiR-223 regulates the differentiation of immature neurons (2014) (23)
- LRRK2 GTPase dysfunction in the pathogenesis of Parkinson's disease. (2012) (23)
- Localization of [3H]forskolin binding sites in the rat brain using quantitative autoradiography. (1984) (23)
- The genetics of Parkinson’s disease (2002) (22)
- Genetic analysis of neurodegenerative diseases in a pathology cohort (2019) (22)
- Parkinson's disease genetic mutations increase cell susceptibility to stress: mutant alpha-synuclein enhances H2O2- and Sin-1-induced cell death. (2007) (21)
- Augmentation of poly(ADP-ribose) polymerase-dependent neuronal cell death by acidosis (2017) (21)
- Recent advances in our understanding of Parkinson's disease (2005) (20)
- Neuronal NLRP3 is a parkin substrate that drives neurodegeneration in Parkinson’s disease (2022) (19)
- Two approaches reveal a new paradigm of ‘switchable or genetics-influenced allele-specific DNA methylation’ with potential in human disease (2017) (19)
- The 12 kD FK506 Binding Protein FKBP12 Is Released in the Male Reproductive Tract and Stimulates Sperm Motility (1998) (19)
- Parkinson’s disease: Genetics and pathogenesis (2007) (18)
- Endonuclease G does not play an obligatory role in poly(ADP-ribose) polymerase-dependent cell death after transient focal cerebral ischemia. (2010) (18)
- Decreased beta-adrenergic receptors in rat brain after chronic administration of the selective serotonin uptake inhibitor fluoxetine (2004) (17)
- Autoradiographic localization of [3H]methylphenidate binding sites in rat brain. (1985) (17)
- Receptor Alterations in Subcortical Structures after Bilateral Middle Cerebral Artery Infarction of the Cerebral Cortex (1994) (17)
- ADP-ribosylation as a mechanism for the action of nitric oxide in the nervous system. (1995) (17)
- Abberant protein synthesis in G2019S LRRK2 Drosophila Parkinson disease-related phenotypes (2014) (17)
- SnapShot: Pathogenesis of Parkinson's Disease (2009) (17)
- PARP and the Release of Apoptosis-Inducing Factor from Mitochondria (2006) (16)
- PARIS farnesylation prevents neurodegeneration in models of Parkinson’s disease (2021) (16)
- Nitric oxide in brain development, plasticity, and disease: Preface (1998) (16)
- Non-autonomous cell death in Parkinson's disease (2008) (16)
- Cognitive impairment in Parkinson's disease: Association between patient-reported and clinically measured outcomes. (2016) (16)
- What have genetically engineered mice taught us about ischemic injury? (2004) (16)
- Assessment of APOE in atypical parkinsonism syndromes (2019) (16)
- TRIP12 ubiquitination of glucocerebrosidase contributes to neurodegeneration in Parkinson’s disease (2021) (16)
- The role of the ubiquitin-proteasomal pathway in Parkinson's disease and other neurodegenerative disorders (2001) (16)
- Complement and coagulation cascades are potentially involved in dopaminergic neurodegeneration in α-synuclein-based mouse models of Parkinson’s disease (2020) (16)
- A comprehensive screening of copy number variability in dementia with Lewy bodies (2019) (16)
- Targeting Parthanatos in Ischemic Stroke (2021) (15)
- P3-228 Chip and HSP70 regulate tau ubiquitination, degradation and aggregation (2004) (15)
- [3H]noscapine binding sites in brain: relationship to indoleamines and the phosphoinositide and adenylyl cyclase messenger systems. (1992) (15)
- Thorase variants are associated with defects in glutamatergic neurotransmission that can be rescued by Perampanel (2017) (15)
- Lysosomal Enzyme Glucocerebrosidase Protects against Aβ1-42 Oligomer-Induced Neurotoxicity (2015) (14)
- Lymphocyte Activation Gene 3 (Lag3) Contributes to α-Synucleinopathy in α-Synuclein Transgenic Mice (2021) (14)
- High-Content Genome-Wide RNAi Screen Reveals CCR3 as a Key Mediator of Neuronal Cell Death (2016) (14)
- Poly-ADP-ribosylation in health and disease (2005) (13)
- Astroglia Induce Cytotoxic Effects on Brain Tumors via a Nitric Oxide-Dependent Pathway Both in Vitro and in Vivo (2004) (13)
- Ironing out tau's role in parkinsonism (2012) (13)
- A Lysosomal Lair for a Pathogenic Protein Pair (2011) (13)
- Neurons Derived from Human Induced Pluripotent Stem Cells Integrate into Rat Brain Circuits and Maintain Both Excitatory and Inhibitory Synaptic Activities (2019) (13)
- Parkin: clinical aspects and neurobiology (2001) (12)
- Neurodegenerative phenotypes in an A 53 T a-synuclein transgenic mouse model are independent of LRRK 2 (2012) (12)
- Unraveling the role of defective genes in Parkinson's disease. (2007) (11)
- Effect of fenbendazole on three behavioral tests in male C57BL/6N mice. (2010) (11)
- Requirement for nitric oxide activation of p21 ras yextracellular regulated kinase in (2000) (11)
- PAAN/MIF nuclease inhibition prevents neurodegeneration in Parkinson’s disease (2022) (11)
- Markers of impaired motor and cognitive volition in Parkinson's disease: Correlates of dopamine dysregulation syndrome, impulse control disorder, and dyskinesias. (2017) (11)
- Large-scale phenotypic drug screen identifies neuroprotectants in zebrafish and mouse models of retinitis pigmentosa (2020) (10)
- Nitric Oxide Synthase Inhibitors (1996) (10)
- Nitric Oxide Synthase Protein and mRNA Are Discretely Localized in Neuronal Populations o Mammalian CNS Together with NADPH Diaphoras (2015) (10)
- Genetics of Parkinson's disease: What do mutations in DJ‐1 tell us? (2003) (10)
- Markers of impaired motor and cognitive volition in Parkinson's disease: Correlates of dopamine dysregulation syndrome, impulse control disorder, and dyskinesias. (2018) (9)
- Brainstem Pathologies Correlate With Depression and Psychosis in Parkinson's Disease. (2021) (9)
- Domain‐specific cognitive impairment in non‐demented Parkinson's disease psychosis (2018) (9)
- Quantitative mass spectrometric analysis of the mouse cerebral cortex after ischemic stroke (2020) (8)
- Parkin interacting substrate phosphorylation by c-Abl drives dopaminergic neurodegeneration. (2021) (8)
- Gene therapy to the rescue in Parkinson's disease. (2001) (8)
- The AAA + ATPase Thorase is neuroprotective against ischemic injury (2019) (8)
- Prevention and regression of megamitochondria and steatosis by blocking mitochondrial fusion in the liver (2022) (8)
- Reduction of functional N‐methyl‐d‐aspartate receptors in neurons by RNase P‐mediated cleavage of the NR1 mRNA (2001) (8)
- AMPA Receptor Surface Expression Is Regulated by S-Nitrosylation of Thorase and Transnitrosylation of NSF (2020) (7)
- C9orf72 Hexanucleotide Repeat Analysis in Cases with Pathologically Confirmed Dementia with Lewy Bodies (2016) (7)
- Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into the complex genetic architecture (2020) (7)
- Therapeutic Potential of a Novel Glucagon-like Peptide-1 Receptor Agonist, NLY01, in Experimental Autoimmune Encephalomyelitis (2021) (7)
- NLRP3 inflammasome activation in dopamine neurons contributes to neurodegeneration in Parkinson’s Disease (2020) (7)
- Aplp1 and the Aplp1-Lag3 Complex facilitates transmission of pathologic α-synuclein (2021) (7)
- Role of Tuberin in Neuronal Degeneration (2008) (7)
- The role of PARKIN in parkinson’s disease (2007) (7)
- Onset and Remission of Psychosis in Parkinson's Disease: Pharmacologic and Motoric Markers (2018) (7)
- Parkinson Disease: Translating Insights from Molecular Mechanisms to Neuroprotection (2021) (7)
- Erratum: In circadian locomotor analysis of male mice lacking the gene for neuronal nitric oxide synthase (nNOS-/-) (Journal of Biological Rhythms (February 1999) 14:1 (20-27)) (1999) (7)
- Usp16: key controller of stem cells in Down syndrome (2013) (6)
- The role of stem cells in Parkinson's disease. (2007) (6)
- Gait function and locus coeruleus Lewy body pathology in 51 Parkinson's disease patients. (2016) (6)
- NILOTINIB IN PATIENTS WITH ADVANCED PARKINSONS DISEASE: A RANDOMIZED PHASE 2A STUDY (NILO-PD) (2020) (6)
- Elevated Urinary Rab10 Phosphorylation in Idiopathic Parkinson Disease (2022) (6)
- Development of a novel method for the quantification of tyrosine 39 phosphorylated α- and β-synuclein in human cerebrospinal fluid (2020) (6)
- Histochemical Analysis of Nitric Oxide Synthase by NADPH Diaphorase Staining (1999) (6)
- Nitric Oxide Neurotoxicity in Primary Neuronal Cultures (1995) (6)
- Generation of isoform-specific antibodies to nitric oxide synthases. (1996) (6)
- Mining for survival genes. (2006) (6)
- Amelioration of pathologic α-synuclein-induced Parkinson’s disease by irisin (2022) (6)
- Neurotoxic Actions and Mechanisms of Nitric Oxide (2000) (6)
- Taming the clot-buster tPA (2006) (6)
- S-nitrosylation of XIAP compromises neuronal survival in Parkinson's disease (Proceedings of the National Academy of Sciences of the United States of America (2009) 106, 12, (4900-4905) DOI: 10.1073/pnas.0810595106) (2009) (5)
- Dysregulated mRNA Translation in the G2019S LRRK2 and LRRK2 Knock-Out Mouse Brains (2021) (5)
- The 350-fold compacted Fugu parkin gene is structurally and functionally similar to human Parkin. (2005) (5)
- Parkinson's disease: clinical manifestations and treatment (2000) (5)
- Corrigendum: Parthanatos mediates AIMP2-activated age-dependent dopaminergic neuronal loss (2015) (5)
- Interleukin-6 triggers toxic neuronal iron sequestration in response to pathological α-synuclein (2022) (5)
- LRRK2 pathobiology in Parkinson's disease – virtual inclusion (2016) (4)
- Semantic fluency and processing speed are reduced in non-cognitively impaired participants with Parkinson’s disease (2021) (4)
- Excitotoxic programmed cell death involves caspase-independent mechanisms (2010) (4)
- Experience-dependent translational state defined by cell type-specific ribosome profiling (2017) (4)
- Revelations and revolutions in the understanding of Parkinson's disease. (2009) (4)
- Molecular Mediation of Prion-like α-Synuclein Fibrillation from Toxic PFFs to Nontoxic Species (2020) (4)
- Protocol for measurement of calcium dysregulation in human induced pluripotent stem cell-derived dopaminergic neurons (2021) (4)
- Protein Translation in Parkinson's Disease (2017) (4)
- Seeking progress in disease modification in Parkinson disease. (2021) (4)
- [2] - Nitric Oxide Toxicity in Central Nervous System Cultures (1996) (4)
- Measuring the activity of leucine-rich repeat kinase 2: a kinase involved in Parkinson's disease. (2012) (3)
- Failures and successes of clinical trials for Parkinson disease treatments. (2005) (3)
- α-Synuclein accumulation and GBA deficiency due to L444P GBA mutation contributes to MPTP-induced parkinsonism (2018) (3)
- Immune response in Parkinson’s disease driven by HLA display of α-synuclein peptides (2017) (3)
- Role of NO in Neurodegeneration (2009) (3)
- Nitric oxide: a brake for bad behavior. (1996) (3)
- Poly(ADP-ribose) promotes toxicity of C9ORF72 arginine-rich dipeptide repeat proteins (2022) (3)
- Deubiquitinase CYLD acts as a negative regulator of dopamine neuron survival in Parkinson's disease. (2022) (3)
- Intracellular Signaling: Mediators and Protective Responses (2004) (3)
- USP39 promotes non-homologous end-joining repair by poly(ADP-ribose)-induced liquid demixing (2021) (3)
- The AAA + ATPase Thorase Regulates (2011) (3)
- Waiting for PARIS—A Biological Target in Search of a Drug (2021) (2)
- Integrative genome-wide analysis of dopaminergic neuron-specific PARIS expression in Drosophila dissects recognition of multiple PPAR-γ associated gene regulation (2021) (2)
- CYFIP1 Dosages Exhibit Divergent Behavioral Impact via Diametric Regulation of NMDA Receptor Complex Translation in Mouse Models of Psychiatric Disorders (2021) (2)
- Reversal of nigrostriatal-lesion-induced receptor alterations by grafting of fetal mesencephalic dopaminergic neurons. (1991) (2)
- Absence of C 9 ORF 72 expanded or intermediate repeats in autopsy confirmed Parkinson Disease (2014) (2)
- AIF3 splicing switch triggers neurodegeneration (2021) (2)
- Pathogenesis of Parkinson's Disease (2010) (2)
- Mass Spectrometry–Based Proteomics Analysis of Human Substantia Nigra From Parkinson's Disease Patients Identifies Multiple Pathways Potentially Involved in the Disease (2022) (2)
- The Absence of Parkin Does Not Promote Dopamine or Mitochondrial Dysfunction in PolgAD257A/D257A Mitochondrial Mutator Mice (2022) (2)
- [6] - NADPH Diaphorase Staining (1996) (2)
- Autoradiographic Localization of Drug and Neurotransmitter Receptors in the Olfactory Bulb (1988) (2)
- Reply: Heterozygous PINK1 p.G411S in rapid eye movement sleep behaviour disorder. (2017) (2)
- CNS Neuroprotection (2002) (2)
- Nitric Oxide in Brain Ischemia/Reperfusion Injury (2000) (2)
- [20] Function of nitric oxide in neuronal cell death (1996) (1)
- Cerebrovascular Disease: Mechanisms of ischemic tolerance (2002) (1)
- Mass spectrometry‐based proteomics analysis of human globus pallidus from progressive supranuclear palsy patients discovers multiple disease pathways (2022) (1)
- AAA + ATPase Thorase inhibits mTOR signaling through the disassembly of the mTOR complex 1 (2022) (1)
- Faculty Opinions recommendation of Sequential activation of poly(ADP-ribose) polymerase 1, calpains, and Bax is essential in apoptosis-inducing factor-mediated programmed necrosis. (2007) (1)
- Identification by mRNA Differential Display of Two Up-regulated Genes as Candidate Mediators of AIDS Dementia (2001) (1)
- Erratum: Preconditioning mediated neuroprotection through erythropoietin? (Lancet (January 12) (96)) (2002) (1)
- The NO Signaling Pathway in the Brain (2000) (1)
- Thrombotic microangiopathy isolated to the central nervous system (1991) (1)
- Dystrophin and nnos double knockout mice maintain dystrophic phenotype (1997) (1)
- Correction for: S-nitrosylation of XIAP compromises neuronal: survival in Parkinson's disease (2009) (1)
- Thursday Oral Session (2009) (1)
- Host regulator PARP1 contributes to sex differences and immune responses in a mouse model of tuberculosis (2021) (1)
- Faculty Opinions recommendation of APOE genotype regulates pathology and disease progression in synucleinopathy. (2020) (1)
- Molecular recording of calcium signaling via calcium-dependent protein proximity labeling (2022) (1)
- The PINK1 p.I368N mutation affects protein stability and disrupts kinase activity (2017) (1)
- A high-affinity cocaine binding site associated with the brain acid soluble protein 1 (2022) (1)
- The NO Signaling Pathway in the Brain Neural Injury, Neurological Disorders, and Aggression (2012) (1)
- Identification and evaluation of NO-regulated genes by differential analysis of primary cDNA library expression (DAzLE). (2005) (1)
- Reply: ATAD1 encephalopathy and stiff baby syndrome: a recognizable clinical presentation. (2018) (1)
- Cell Biology of Parkin: Clues to the Development of New Therapeutics for Parkinson’s Disease (2022) (1)
- An image registration pipeline for analysis of transsynaptic tracing in mice (2016) (1)
- Bi-allelic TTI1 variants cause an autosomal-recessive neurodevelopmental disorder with microcephaly. (2023) (1)
- DNA Methylation Signature of Aging: Potential Impact on the Pathogenesis of Parkinson’s Disease (2023) (1)
- The PINK1 p.I368N Mutation Affects Protein Stability and Kinase Activity with Its Structural Change (2018) (1)
- Genetic Models of Familial Parkinson's Disease (2008) (1)
- Parthanatos: PARP- and AIF-dependent programmed cell death (2008) (1)
- The c-Abl inhibitor IkT-148009 suppresses neurodegeneration in mouse models of heritable and sporadic Parkinson’s disease (2023) (1)
- The PINK1 p.I368N mutation affects protein stability and ubiquitin kinase activity (2017) (0)
- S4-03-02 Role of parkin in defective ubiquitination and alpha-synuclein turnover in parkinson's disease (2004) (0)
- Animal models of neurodegenerative diseases (2018) (0)
- Faculty Opinions recommendation of Poly (ADP-ribose) polymerase 1 and Parkinson's disease: A study in post-mortem human brain. (2021) (0)
- INTERNATIONAL BEHAVIOURAL AND NEURAL GENETICS SOCIETY KNOCKOUTS & MUTANTS II: Genetically Dissecting Brain and Behavior (2007) (0)
- Neurobiology of Disease Apoptosis-Inducing Factor Substitutes for Caspase Executioners in NMDA-Triggered Excitotoxic Neuronal (2004) (0)
- Inhibitors of LRRK 2 kinase attenuate neurodegeneration and Parkinson-like phenotypes in C . elegans and Drosophila Parkinson ’ s disease models (2011) (0)
- AIF3 splicing switch triggers neurodegeneration (2021) (0)
- PARP1 Knock-Out Mice Prevents N-methyl-N-nitrosourea-induced Photoreceptor Degeneration (2013) (0)
- Ubiquitination by Parkin — Implications in Parkinson’s Disease (2006) (0)
- Faculty Opinions recommendation of Complement drives glucosylceramide accumulation and tissue inflammation in Gaucher disease. (2017) (0)
- Dysregulated phosphorylation of Rab GTPases by LRRK2 induces neurodegeneration (2018) (0)
- Faculty Opinions recommendation of Pathological α-synuclein transmission initiates Parkinson-like neurodegeneration in nontransgenic mice. (2012) (0)
- Genome-wide structural variant analysis identifies risk loci for non-Alzheimer’s dementias (2023) (0)
- Comprar Parkinsons Disease: Genetics and Pathogenesis | Ted M. Dawson | 9780849336973 | Informa Healthcare (2007) (0)
- Correction: Resistance to MPTP-Neurotoxicity in α-Synuclein Knockout Mice Is Complemented by Human α-Synuclein and Associated with Increased β-Synuclein and Akt Activation (2012) (0)
- Overview of the Pathway and Functions of Nitric Oxide (1999) (0)
- Molecular mechanisms of neuronal cell death in animal models of Parkinson's disease (2000) (0)
- Apoptotic cell death in disease—Current understanding of the NCCD 2023 (2023) (0)
- Glial pathology and retinal neurotoxicity in the anterior visual pathway in experimental autoimmune encephalomyelitis (2019) (0)
- Differences in Quality of Life Between Men and Women with Parkinson’s Disease (P2.081) (2018) (0)
- NO parkin in Parkinson's disease [5] (multiple letters) (2004) (0)
- PARIS induced defects in mitochondrial biogenesis drive dopamine neuron loss under conditions of parkin or PINK1 deficiency (2020) (0)
- Evaluation of LRRK2 Transgenic Mice as a Novel Model of Parkinson’s Disease. (2008) (0)
- Faculty Opinions recommendation of A neo-substrate that amplifies catalytic activity of parkinson's-disease-related kinase PINK1. (2013) (0)
- Poly ADP-Ribose Signaling is Dysregulated in Huntington’s Disease Patients (2022) (0)
- Blocking nitric oxide toxicity : Mechanical approaches of CNS neuroprotection (2002) (0)
- Parkin and Neurodegeneration (2007) (0)
- Role of poly(ADP-Ribose) polymerase-1 in neurologic disorders (2002) (0)
- Development of a novel method for the quantification of tyrosine 39 phosphorylated alpha-synuclein in human cerebrospinal fluid (2020) (0)
- Atp7b-dependent choroid plexus dysfunction causes transient copper deficit and metabolic changes in the developing mouse brain (2023) (0)
- PINK1 and Parkin mitochondrial quality control: a source of regional vulnerability in Parkinson’s disease (2020) (0)
- Re: Ropinorole and Dyskinesias in Early Treatment of Parkinson's Disease (2017) (0)
- Faculty Opinions recommendation of Apoptosis-inducing factor is a major contributor to neuronal loss induced by neonatal cerebral hypoxia-ischemia. (2006) (0)
- Rotamase activity enzyme inhibitors (1996) (0)
- Integration of Human Induced Pluripotent Stem Cell (hiPSC)-Derived Neurons into Rat Brain Circuits. (2020) (0)
- LRRK2 Modulates the Exocyst Complex Assembly by Interacting with Sec8 (2021) (0)
- Blocking microglial activation of reactive astrocytes is neuroprotective in models of Alzheimer’s disease (2021) (0)
- Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson’s disease (2018) (0)
- KNOCKOUTS & MUTANTS III : Genetically Dissecting Brain and Behavior THIRD ANNUAL GENERAL MEETING June 22-June 23 , 2000 (2007) (0)
- Contents Vol. 16, 2016 (2016) (0)
- Heterozygous PINK1 p.G411S mutation increases risk for Parkinson's disease (PD) (2016) (0)
- Faculty Opinions recommendation of Akt and CHIP coregulate tau degradation through coordinated interactions. (2008) (0)
- Inhibition ofNeuronalNitricOxide SynthaseIncreases Aggressive Behavior inMice (1997) (0)
- APDM gait and balance measures fail to predict symptom progression rate in Parkinson's disease (2022) (0)
- A perfect “Match” for in vitro human disease modeling and autologous cell‐based transplantation therapy: Generating genetically identical Parkinson's disease and control pluripotent stem cells by precise gene targeting (2011) (0)
- 10 – Intracellular Signaling: Mediators and Protective Responses (2011) (0)
- Faculty Opinions recommendation of CRISPaint allows modular base-specific gene tagging using a ligase-4-dependent mechanism. (2016) (0)
- ACE2-expressing endothelial cells in aging mouse brain (2020) (0)
- Faculty Opinions recommendation of TBK1 Suppresses RIPK1-Driven Apoptosis and Inflammation during Development and in Aging. (2019) (0)
- A new Perspective on Parkinson's disease: exploring the involvement of intestine and vagus lysates in α-synucleinopathy propagation (2023) (0)
- Pharmacologic inhibition of MIF nuclease: A new treatment paradigm to treat cell death (2022) (0)
- Nitric Oxide Actions in the Nervous System (1996) (0)
- Nitrosative signaling in cell death and cell survival (2011) (0)
- Differential Methylation Analysis in Neuropathologically Confirmed Dementia with Lewy Bodies (2022) (0)
- Faculty Opinions recommendation of Potentiated Hsp104 variants antagonize diverse proteotoxic misfolding events. (2014) (0)
- Title Pathological Endogenous α-Synuclein Accumulation in Oligodendrocyte Precursor Cells Potentially Induces Inclusions in Multiple System Atrophy (2018) (0)
- Gaseous Signaling: Nitric Oxide and Carbon Monoxide as Messenger Molecules (2007) (0)
- Faculty Opinions recommendation of Atg32 is a mitochondrial protein that confers selectivity during mitophagy. (2009) (0)
- Neurobiology of AIF and PARP in cerebral ischemia (2007) (0)
- Association Studies of Neuropathologically-Confirmed Cases and Controls Reveals that the PARK10 Locus is a Major Contributor to Sporadic Parkinson disease. (S7.005) (2015) (0)
- Inhibitors of poly (ADP-ribos) syntetas Science anvaendning daerav Foer in that foerhindra NMDA nervfoergiftning (1996) (0)
- NITRIC OXIDE MEDIATES A COMPONENT OF gp120 NEUROTOXICITY IN PRIMARY CORTICAL CULTURES (1995) (0)
- Role of poly(ADP-ribose) polymerase mediating acute and chronic neuronal injury and neurodegeneration (2000) (0)
- Reactive nitrogen intermediates: Effector molecules of immune‐mediated inflammatory nervous system disorders? (1993) (0)
- Enhanced mTORC1 signaling and Protein Synthesis in Parkinson’s Disease Pathogenesis Disease Pathogenesis (2022) (0)
- 236; THE EFFECT OF HEMORRHAGIC HYPOTENSION, and RETRANSFUSION ON REGIONAL CEREBRAL NITRIC OXIDE SYNTHASE ACTIVITY, and CORTICAL NO CONTENT IN THE CAT (1994) (0)
- Development of a novel method for the quantification of tyrosine 39 phosphorylated α- and β-synuclein in human cerebrospinal fluid (2020) (0)
- Proteome-wide microarray-based screening of PAR-binding proteins (2022) (0)
- Blocking Nitric Oxide Toxicity (2002) (0)
- Alterations of dopamine receptor subtypes in the rat CNS following methamphetamine treatment (1985) (0)
- 15 – Parkinson Disease: Molecular Insights (2007) (0)
- Intracellular Signaling: Mediators and Protective Responses. Mediators and Protective Responses. (2015) (0)
- Faculty Opinions recommendation of Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro. (2010) (0)
- Section IV: Animal Models (2007) (0)
- BY GRAFTING OF FETAL MESENCEPHALIC DOPAMINERGIC NEURONS (1991) (0)
- Faculty Opinions recommendation of Pharmacological promotion of inclusion formation: a therapeutic approach for Huntington's and Parkinson's diseases. (2006) (0)
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What Schools Are Affiliated With Ted Murray Dawson?
Ted Murray Dawson is affiliated with the following schools:
