Teri Manolio
Physician, epidemiologist, and geneticist
Teri Manolio's AcademicInfluence.com Rankings
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Medical Biology
Teri Manolio's Degrees
- Doctorate Medicine University of Washington
- Masters Public Health Johns Hopkins University
- PhD Genetics University of Washington
Why Is Teri Manolio Influential?
(Suggest an Edit or Addition)According to Wikipedia, Teri Ann Manolio is an American physician, epidemiologist, and geneticist. She is director of the Division of Genomic Medicine at the National Human Genome Research Institute , as well as Professor of Medicine at the Uniformed Services University of the Health Sciences. She is a fellow of the American College of Physicians and of the American Heart Association's Council on Epidemiology. She also has a clinical appointment at the Walter Reed National Military Medical Center in Bethesda, Maryland. Before joining the NHGRI, she worked on large cohort studies, such as the Cardiovascular Health Study and the Framingham Heart Study, at the National Heart, Lung, and Blood Institute.
Teri Manolio's Published Works
Published Works
- Finding the missing heritability of complex diseases (2009) (7749)
- Carotid-artery intima and media thickness as a risk factor for myocardial infarction and stroke in older adults. Cardiovascular Health Study Collaborative Research Group. (1999) (4110)
- Potential etiologic and functional implications of genome-wide association loci for human diseases and traits (2009) (4004)
- The Cardiovascular Health Study: design and rationale. (1991) (3623)
- Heart disease and stroke statistics--2006 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. (2006) (3370)
- The NHGRI GWAS Catalog, a curated resource of SNP-trait associations (2013) (2650)
- Genomewide association studies and assessment of the risk of disease. (2010) (1538)
- Incidence of and risk factors for atrial fibrillation in older adults. (1997) (1461)
- Clinical correlates of white matter findings on cranial magnetic resonance imaging of 3301 elderly people. The Cardiovascular Health Study. (1996) (1459)
- Replicating genotype–phenotype associations (2007) (1367)
- Ankle-arm index as a marker of atherosclerosis in the Cardiovascular Health Study. Cardiovascular Heart Study (CHS) Collaborative Research Group. (1993) (1181)
- Guidelines for investigating causality of sequence variants in human disease (2014) (1160)
- Prevalence of atrial fibrillation in elderly subjects (the Cardiovascular Health Study). (1994) (1146)
- How to interpret a genome-wide association study. (2008) (1004)
- A HapMap harvest of insights into the genetics of common disease. (2008) (939)
- Ankle-arm index as a predictor of cardiovascular disease and mortality in the Cardiovascular Health Study. The Cardiovascular Health Study Group. (1999) (908)
- Genome partitioning of genetic variation for complex traits using common SNPs (2011) (869)
- Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data (2013) (763)
- Elevations of Inflammatory and Procoagulant Biomarkers in Elderly Persons With Renal Insufficiency (2003) (763)
- Cardiovascular disease in women: a statement for healthcare professionals from the American Heart Association. Writing Group. (1997) (682)
- The Electronic Medical Records and Genomics (eMERGE) Network: past, present, and future (2013) (596)
- Cardiovascular mortality risk in chronic kidney disease: comparison of traditional and novel risk factors. (2005) (591)
- Use of sonography to evaluate carotid atherosclerosis in the elderly. The Cardiovascular Health Study. CHS Collaborative Research Group. (1991) (566)
- Recruitment of adults 65 years and older as participants in the Cardiovascular Health Study. (1993) (562)
- Detectable clonal mosaicism from birth to old age and its relationship to cancer (2012) (514)
- Lacunar infarcts defined by magnetic resonance imaging of 3660 elderly people: the Cardiovascular Health Study. (1998) (501)
- Outcome of Congestive Heart Failure in Elderly Persons: Influence of Left Ventricular Systolic Function: The Cardiovascular Health Study (2002) (490)
- Abundant pleiotropy in human complex diseases and traits. (2011) (477)
- Implementing genomic medicine in the clinic: the future is here (2013) (463)
- Assuring the quality of next-generation sequencing in clinical laboratory practice (2012) (444)
- Daytime Sleepiness Predicts Mortality and Cardiovascular Disease in Older Adults (2000) (441)
- Magnetic resonance abnormalities and cardiovascular disease in older adults. The Cardiovascular Health Study. (1994) (439)
- Stroke following coronary artery bypass grafting: a ten-year study. (1985) (435)
- Prevalence and etiology of idiopathic dilated cardiomyopathy (summary of a National Heart, Lung, and Blood Institute workshop. (1992) (434)
- Incidence, Manifestations, and Predictors of Worsening White Matter on Serial Cranial Magnetic Resonance Imaging in the Elderly: The Cardiovascular Health Study (2005) (429)
- Blood pressure response during treadmill testing as a risk factor for new-onset hypertension. The Framingham heart study. (1999) (428)
- Quality control and quality assurance in genotypic data for genome‐wide association studies (2010) (425)
- The Role of APOE ∊4 in Modulating Effects of Other Risk Factors for Cognitive Decline in Elderly Persons (1999) (424)
- Respiratory muscle strength in the elderly. Correlates and reference values. Cardiovascular Health Study Research Group. (1994) (405)
- Cholesterol and heart disease in older persons and women. Review of an NHLBI workshop. (1992) (386)
- C-Reactive Protein and the 10-Year Incidence of Coronary Heart Disease in Older Men and Women: The Cardiovascular Health Study (2005) (375)
- Silent MRI infarcts and the risk of future stroke (2001) (364)
- Sleep Disturbance, Psychosocial Correlates, and Cardiovascular Disease in 5201 Older Adults: The Cardiovascular Health Study (1997) (347)
- Bringing genome-wide association findings into clinical use (2013) (346)
- Relationship of cardiovascular risk factors to echocardiographic left ventricular mass in healthy young black and white adult men and women. The CARDIA study. Coronary Artery Risk Development in Young Adults. (1995) (344)
- Association of Carotid Artery Intima-Media Thickness, Plaques, and C-Reactive Protein With Future Cardiovascular Disease and All-Cause Mortality: The Cardiovascular Health Study (2007) (344)
- Increased left ventricular mass is a risk factor for the development of a depressed left ventricular ejection fraction within five years: the Cardiovascular Health Study. (2004) (342)
- C-Reactive Protein, Carotid Intima-Media Thickness, and Incidence of Ischemic Stroke in the Elderly: The Cardiovascular Health Study (2003) (336)
- Electronic Medical Records for Genetic Research: Results of the eMERGE Consortium (2011) (333)
- Human polymorphism at microRNAs and microRNA target sites. (2013) (330)
- Quality Control Procedures for Genome‐Wide Association Studies (2011) (330)
- Risk factors : Prevention and Rehabilitation of Stroke (1997) (327)
- Relationship between ApoE, MRI findings, and cognitive function in the Cardiovascular Health Study. (1998) (321)
- New models of collaboration in genome-wide association studies: the Genetic Association Information Network (2007) (313)
- Genes, environment and the value of prospective cohort studies (2006) (305)
- Silent brain infarction on magnetic resonance imaging and neurological abnormalities in community-dwelling older adults. The Cardiovascular Health Study. CHS Collaborative Research Group. (1997) (303)
- Cognitive Impairment and Decline Are Associated with Carotid Artery Disease in Patients without Clinically Evident Cerebrovascular Disease (2004) (297)
- Prevalence of subclinical atherosclerosis and cardiovascular disease and association with risk factors in the Cardiovascular Health Study. (1994) (297)
- Short-term predictors of incident stroke in older adults. The Cardiovascular Health Study. (1996) (295)
- American Heart Association Prevention Conference. IV. Prevention and Rehabilitation of Stroke. Risk factors. (1997) (294)
- Familial aggregation of atrial fibrillation in Iceland. (2006) (291)
- Incidence, Manifestations, and Predictors of Brain Infarcts Defined by Serial Cranial Magnetic Resonance Imaging in the Elderly: The Cardiovascular Health Study (2002) (289)
- The prevalence and risk factors of retinal microvascular abnormalities in older persons: The Cardiovascular Health Study. (2003) (283)
- Left atrial volume, geometry, and function in systolic and diastolic heart failure of persons > or =65 years of age (the cardiovascular health study). (2006) (283)
- Racial differences in serum cotinine levels among smokers in the Coronary Artery Risk Development in (Young) Adults study. (1990) (281)
- Sex, age, and disease affect echocardiographic left ventricular mass and systolic function in the free-living elderly. The Cardiovascular Health Study. (1995) (268)
- Major electrocardiographic abnormalities in persons aged 65 years and older (the Cardiovascular Health Study). Cardiovascular Health Study Collaborative Research Group. (1992) (265)
- The ClinSeq Project: piloting large-scale genome sequencing for research in genomic medicine. (2009) (262)
- Cardiovascular risk factors in young adults. The CARDIA baseline monograph. (1991) (260)
- Prevalence and correlates of snoring and observed apneas in 5,201 older adults. (1996) (251)
- Variants near FOXE1 are associated with hypothyroidism and other thyroid conditions: using electronic medical records for genome- and phenome-wide studies. (2011) (248)
- Respiratory muscle strength in the elderly : correlates and reference values (1994) (246)
- Prioritizing diversity in human genomics research (2017) (246)
- The role of APOE epsilon4 in modulating effects of other risk factors for cognitive decline in elderly persons. (1999) (237)
- Integrating Genomics into Healthcare: A Global Responsibility. (2019) (221)
- Hostility and health behaviors in young adults: the CARDIA Study. Coronary Artery Risk Development in Young Adults Study. (1992) (218)
- The HapMap and genome-wide association studies in diagnosis and therapy. (2009) (218)
- Exercise blood pressure response and 5-year risk of elevated blood pressure in a cohort of young adults: the CARDIA study. (1994) (217)
- Associations of Postmenopausal Estrogen Use With Cardiovascular Disease and Its Risk Factors in Older Women (1993) (214)
- Association of fasting insulin with blood pressure and lipids in young adults. The CARDIA study. (1990) (213)
- Echocardiographic design of a multicenter investigation of free-living elderly subjects: the Cardiovascular Health Study. (1992) (211)
- Infarctlike lesions in the brain: prevalence and anatomic characteristics at MR imaging of the elderly--data from the Cardiovascular Health Study. (1997) (210)
- A method for using MR to evaluate the effects of cardiovascular disease on the brain: the cardiovascular health study. (1994) (209)
- Genetic variants at 2q24 are associated with susceptibility to type 2 diabetes. (2010) (208)
- Reporting genetic results in research studies: Summary and recommendations of an NHLBI working group (2006) (203)
- Prevalence, predisposing factors, and prognosis of clinically unrecognized myocardial infarction in the elderly. (2000) (202)
- Fish consumption and stroke risk in elderly individuals: the cardiovascular health study. (2005) (201)
- Design and Anticipated Outcomes of the eMERGE-PGx Project: A Multi-Center Pilot for Pre-Emptive Pharmacogenomics in Electronic Health Record Systems (2014) (196)
- Relationships of cerebral MRI findings to ultrasonographic carotid atherosclerosis in older adults : the Cardiovascular Health Study. CHS Collaborative Research Group. (1999) (196)
- Definitions for Acute Coronary Heart Disease in Epidemiology and Clinical Research Studies (2003) (194)
- Trends in pharmacologic management of hypertension in the United States. (1995) (188)
- eXclusion: toward integrating the X chromosome in genome-wide association analyses. (2013) (187)
- Novel risk markers and clinical practice. (2003) (184)
- Global implementation of genomic medicine: We are not alone (2015) (183)
- The IGNITE network: a model for genomic medicine implementation and research (2015) (180)
- Research as a part of public health emergency response. (2013) (179)
- Hypertension and cognitive function: Pathophysiologic effects of hypertension on the brain (2003) (175)
- Predictors of loss of lung function in the elderly: the Cardiovascular Health Study. (2001) (168)
- Cardiovascular disease risk status in elderly persons with renal insufficiency. (2002) (168)
- Vascular events, mortality, and preventive therapy following ischemic stroke in the elderly (2005) (165)
- Time trends in high blood pressure control and the use of antihypertensive medications in older adults: the Cardiovascular Health Study. (2002) (165)
- Quantifying realistic sample size requirements for human genome epidemiology (2008) (163)
- Genome- and Phenome-Wide Analyses of Cardiac Conduction Identifies Markers of Arrhythmia Risk (2013) (163)
- The gene, environment association studies consortium (GENEVA): maximizing the knowledge obtained from GWAS by collaboration across studies of multiple conditions (2010) (161)
- Alcohol intake and blood pressure in young adults: the CARDIA Study. (1990) (160)
- The Next PAGE in Understanding Complex Traits: Design for the Analysis of Population Architecture Using Genetics and Epidemiology (PAGE) Study (2011) (158)
- Cardiac arrhythmias on 24-h ambulatory electrocardiography in older women and men: the Cardiovascular Health Study. (1994) (155)
- Association of Arrhythmia-Related Genetic Variants With Phenotypes Documented in Electronic Medical Records. (2016) (155)
- Cigarette smoking behavior is strongly related to educational status: the CARDIA study. (1990) (154)
- Genetic Determinants of Lipid Traits in Diverse Populations from the Population Architecture using Genomics and Epidemiology (PAGE) Study (2011) (153)
- Correlates of obesity in young black and white women: the CARDIA Study. (1992) (152)
- Genetic variation among 82 pharmacogenes: The PGRNseq data from the eMERGE network (2016) (149)
- Lipoprotein Lipids in Older People: Results From the Cardiovascular Health Study (1992) (146)
- Clinical significance of calcification of the fibrous skeleton of the heart and aortosclerosis in community dwelling elderly. The Cardiovascular Health Study (CHS). (2006) (145)
- Intrinsic contribution of gender and ethnicity to normal ankle-brachial index values: the Multi-Ethnic Study of Atherosclerosis (MESA). (2007) (144)
- Clinical Sequencing Exploratory Research Consortium: Accelerating Evidence-Based Practice of Genomic Medicine. (2016) (143)
- Relation of alcohol intake to left ventricular mass: The Framingham Study. (1991) (142)
- Clinical Correlates of Ventricular and Sulcal Size on Cranial Magnetic Resonance Imaging of 3,301 Elderly People (1999) (142)
- Cohort studies and the genetics of complex disease (2009) (137)
- Lung function and pulmonary regurgitation limit exercise capacity in postoperative tetralogy of Fallot. (1991) (134)
- Does the association of risk factors and atherosclerosis change with age? An analysis of the combined ARIC and CHS cohorts. The Atherosclerosis Risk in Communities (ARIC) and Cardiovascular Health Study (CHS) investigators. (1997) (132)
- Strategic vision for improving human health at The Forefront of Genomics (2020) (130)
- A stroke prediction score in the elderly: validation and Web-based application. (2002) (128)
- Long-term valvular function after total repair of tetralogy of Fallot. Relation to ventricular arrhythmias. (1988) (128)
- Cystatin C and subclinical brain infarction. (2005) (127)
- SJS/TEN 2017: Building Multidisciplinary Networks to Drive Science and Translation. (2018) (126)
- The leucocyte count: correlates and relationship to coronary risk factors: the CARDIA study. (1990) (124)
- Unrecognized Myocardial Infarction (2001) (124)
- Retinal Microvascular Signs, Cognitive Function, and Dementia in Older Person: The Cardiovascular Health Study (2007) (123)
- Acculturation is associated with hypertension in a multiethnic sample. (2007) (121)
- Cardiovascular Disease and Mortality in Older Adults with Small Abdominal Aortic Aneurysms Detected by Ultrasonography: The Cardiovascular Health Study (2001) (120)
- Women's Ischemic Syndrome Evaluation: current status and future research directions: report of the National Heart, Lung and Blood Institute workshop: October 2-4, 2002: executive summary. (2004) (119)
- Temporal trends in the use of anticoagulants among older adults with atrial fibrillation. (1999) (117)
- Risk factors for declining ankle-brachial index in men and women 65 years or older: the Cardiovascular Health Study. (2005) (117)
- Long-term results of total repair of tetralogy of Fallot in childhood. (1990) (117)
- The Emergence of Networks in Human Genome Epidemiology: Challenges and Opportunities (2007) (112)
- Associations between findings on cranial magnetic resonance imaging and retinal photography in the elderly: the Cardiovascular Health Study. (2006) (111)
- Education and the cognitive decline associated with MRI-defined brain infarct (2006) (111)
- Overview of the Jackson Heart Study: a study of cardiovascular diseases in African American men and women. (1999) (111)
- Size matters: just how big is BIG? (2008) (108)
- New Models for Large Prospective Studies: Is There a Better Way? (2012) (107)
- Oral anticoagulation in patients with atrial fibrillation: adherence with guidelines in an elderly cohort. (1999) (103)
- 10-year follow-up of subclinical cardiovascular disease and risk of coronary heart disease in the Cardiovascular Health Study. (2006) (102)
- Gene‐environment interplay in common complex diseases: forging an integrative model—recommendations from an NIH workshop (2011) (99)
- Genetic architecture of cancer and other complex diseases: lessons learned and future directions. (2011) (99)
- Incidence of Cardiovascular Disease in Older Americans: The Cardiovascular Health Study (2005) (98)
- Usefulness of T-axis deviation as an independent risk indicator for incident cardiac events in older men and women free from coronary heart disease (the Cardiovascular Health Study). (2001) (96)
- Research Directions in the Clinical Implementation of Pharmacogenomics: An Overview of US Programs and Projects (2018) (93)
- Black-white differences in subclinical cardiovascular disease among older adults: The cardiovascular health study (1995) (93)
- Bedside Back to Bench: Building Bridges between Basic and Clinical Genomic Research (2017) (92)
- Consistency of genome-wide associations across major ancestral groups (2012) (90)
- Preinduction of anesthesia in children with rectally administered midazolam. (1991) (88)
- Major stroke after coronary artery bypass surgery: changing magnitude of the problem. (1986) (87)
- Temporal patterns of antihypertensive medication use among older adults, 1989 through 1992. An effect of the major clinical trials on clinical practice? (1995) (84)
- Respiratory muscle strength and the risk of incident cardiovascular events (2004) (83)
- White matter grade and ventricular volume on brain MRI as markers of longevity in the cardiovascular health study (2007) (83)
- Cardiac function in smokers and nonsmokers: the CARDIA study. The Coronary Artery Risk Development in Young Adults Study. (1995) (80)
- Protocol for a prospective collaborative overview of all current and planned randomized trials of cholesterol treatment regimens. Cholesterol Treatment Trialists' (CTT) Collaboration. (1995) (79)
- Associations between metabolomic compounds and incident heart failure among African Americans: the ARIC Study. (2013) (79)
- Genetics of ultrasonographic carotid atherosclerosis. (2004) (78)
- Reduced vital capacity in elderly persons with hypertension, coronary heart disease, or left ventricular hypertrophy. The Cardiovascular Health Study. (1995) (78)
- Anthropometric and physiologic correlates of mitral valve prolapse in a biethnic cohort of young adults: the CARDIA study. (1999) (77)
- Ethnic differences in the relationship of carotid atherosclerosis to coronary calcification: the Multi-Ethnic Study of Atherosclerosis. (2008) (77)
- Sex- and race-related differences in liver-associated serum chemistry tests in young adults in the CARDIA study. (1992) (77)
- Utility of new electrocardiographic models for left ventricular mass in older adults. The Cardiovascular Health Study Collaborative Research Group. (1996) (76)
- Enhancing the feasibility of large cohort studies. (2010) (74)
- Evaluation of the Metabochip Genotyping Array in African Americans and Implications for Fine Mapping of GWAS-Identified Loci: The PAGE Study (2012) (72)
- A comparison of death certificate out-of-hospital coronary heart disease death with physician-adjudicated sudden cardiac death. (2005) (72)
- Pitfalls of merging GWAS data: lessons learned in the eMERGE network and quality control procedures to maintain high data quality (2011) (71)
- CHRNB3 is more strongly associated with Fagerström test for cigarette dependence-based nicotine dependence than cigarettes per day: phenotype definition changes genome-wide association studies results. (2012) (70)
- Genomic medicine for undiagnosed diseases (2019) (69)
- Subclinical cardiovascular disease in older adults: insights from the Cardiovascular Health Study. (2004) (69)
- The association of microalbuminuria with clinical cardiovascular disease and subclinical atherosclerosis in the elderly: the Cardiovascular Health Study. (2006) (68)
- Epidemiology of Low Cholesterol Levels in Older Adults The Cardiovascular Health Study (1993) (68)
- Characteristics and Baseline Clinical Predictors of Future Fatal Versus Nonfatal Coronary Heart Disease Events in Older Adults: The Cardiovascular Health Study (2006) (67)
- Merging and emerging cohorts: Necessary but not sufficient (2007) (66)
- Risk ratios and risk differences in estimating the effect of risk factors for cardiovascular disease in the elderly. (1990) (66)
- Correlates of fasting insulin levels in young adults: the CARDIA study. (1991) (64)
- The Genomic Applications in Practice and Prevention Network (2009) (63)
- Cluster analysis and patterns of findings on cranial magnetic resonance imaging of the elderly: the Cardiovascular Health Study. (2001) (63)
- Predictive Utility of Polygenic Risk Scores for Coronary Heart Disease in Three Major Racial and Ethnic Groups. (2020) (62)
- Complement receptor 1 gene variants are associated with erythrocyte sedimentation rate. (2011) (61)
- A new statistic and its power to infer membership and phenotype in a genome-wide association study using genotype frequencies (2009) (59)
- Current estrogen-progestin and estrogen replacement therapy in elderly women: Association with carotid atherosclerosis (1996) (59)
- Women's Ischemic Syndrome Evaluation: current status and future research directions: report of the National Heart, Lung and Blood Institute workshop: October 2-4, 2002: Section 5: gender-related risk factors for ischemic heart disease. (2004) (58)
- Harmonizing Clinical Sequencing and Interpretation for the eMERGE III Network. (2019) (58)
- Genotype Imputation of MetabochipSNPs Using a Study‐Specific Reference Panel of ∼4,000 Haplotypes in African Americans From the Women's Health Initiative (2012) (57)
- Meat consumption and its associations with other diet and health factors in young adults: the CARDIA study. (1991) (55)
- Assessing and managing risk when sharing aggregate genetic variant data (2011) (55)
- C-Reactive Protein, Carotid Intima-Media Thickness, and Incidence of Ischemic Stroke in the Elderly (2003) (53)
- News from the NIH: potential contributions of the behavioral and social sciences to the precision medicine initiative (2015) (51)
- Biallelic Mutations in ATP5F1D, which Encodes a Subunit of ATP Synthase, Cause a Metabolic Disorder (2018) (51)
- High rates of obesity and cardiovascular disease risk factors in lower middle class community in Pakistan: the Metroville Health Study. (2006) (51)
- Left atrial dimensions determined by M-mode echocardiography in black and white older (> or =65 years) adults (The Cardiovascular Health Study). (2002) (51)
- Collaborative genome-wide association studies of diverse diseases: programs of the NHGRI's office of population genomics. (2009) (50)
- Leveraging the electronic health record to implement genomic medicine (2012) (50)
- Carotid artery measures are strongly associated with left ventricular mass in older adults (a report from the Cardiovascular Health Study). (1996) (50)
- Opportunities, resources, and techniques for implementing genomics in clinical care (2019) (49)
- Environmental tobacco smoke exposure as determined by cotinine in black and white young adults: the CARDIA Study. (1993) (49)
- Stroke risk factors and loss of high cognitive function (2004) (49)
- Characterizing genetic variants for clinical action (2014) (48)
- Coronary heart disease. At the interface of molecular genetics and preventive medicine. (1999) (47)
- The emerging importance of genetics in epidemiologic research II. Issues in study design and gene mapping. (1999) (47)
- Genetic variants at 2 q 24 are associated with susceptibility to type 2 diabetes (2010) (46)
- Genetic Loci implicated in erythroid differentiation and cell cycle regulation are associated with red blood cell traits. (2012) (46)
- Genes, Environment, Health, and Disease: Facing up to Complexity (2007) (46)
- High Density GWAS for LDL Cholesterol in African Americans Using Electronic Medical Records Reveals a Strong Protective Variant in APOE (2012) (46)
- A window into living with an undiagnosed disease: illness narratives from the Undiagnosed Diseases Network (2017) (44)
- Correlates of QT prolongation in older adults (the Cardiovascular Health Study). Cardiovascular Health Study Collaborative Research Group. (1994) (44)
- The effects of age on outcome after coronary bypass surgery. (1987) (44)
- Genome‐Wide Association Study of a Heart Failure Related Metabolomic Profile Among African Americans in the Atherosclerosis Risk in Communities (ARIC) Study (2013) (44)
- Differences in prevalence of and risk factors for subclinical vascular disease among black and white participants in the Cardiovascular Health Study. (1998) (43)
- A genome-wide association study identifies variants in KCNIP4 associated with ACE inhibitor-induced cough (2015) (43)
- Genetic Variants That Confer Resistance to Malaria Are Associated with Red Blood Cell Traits in African-Americans: An Electronic Medical Record-based Genome-Wide Association Study (2013) (42)
- Incidence and correlates of hypertension in the Atherosclerosis Risk in Communities (ARIC) study and the Monitoring Trends and Determinants of Cardiovascular Disease (POL‐MONICA) project (2000) (42)
- Aspirin use and incident stroke in the cardiovascular health study. CHS Collaborative Research Group. (1998) (41)
- Apolipoprotein L1 Variants and Blood Pressure Traits in African Americans. (2017) (40)
- The HuGENetTM HuGE Review Handbook, version 1.0 (2006) (39)
- Black-white differences in subclinical cardiovascular disease among older adults: the Cardiovascular Health Study. CHS Collaborative Research Group. (1995) (38)
- Lack of association of the plasminogen activator inhibitor‐1 4G/5G promoter polymorphism with cardiovascular disease in the elderly (2003) (37)
- The growing role of professional societies in educating clinicians in genomics (2014) (35)
- Properties of the random zero sphygmomanometer. (1993) (35)
- Association of lipids and lipoprotein level with total mortality and mortality caused by cardiovascular and cancer diseases (Poland and United States collaborative study on cardiovascular epidemiology). (1999) (34)
- Estrogen Replacement Therapy and MRI‐Demonstrated Cerebral Infarcts, White Matter Changes, and Brain Atrophy in Older Women: The Cardiovascular Health Study (2000) (33)
- Spirometry Reference Values for Healthy Elderly Blacks (1996) (33)
- Partial Loss of USP9X Function Leads to a Male Neurodevelopmental and Behavioral Disorder Converging on Transforming Growth Factor β Signaling (2020) (33)
- Prevalence of specific variant carotid geometric patterns and incidence of cardiovascular events in older persons. The Cardiovascular Health Study (CHS E-131). (2004) (32)
- Genome-Wide Association Analysis of Ischemic Stroke in Young Adults (2011) (31)
- Characterization of Idiopathic Scoliosis in a Clinically Well-Defined Population (2001) (30)
- Translational research is a key to nongeneticist physicians’ genomics education (2014) (30)
- Genomics Reaches the Clinic: From Basic Discoveries to Clinical Impact (2011) (30)
- Age as a predictor of outcome: what role does it play? (1992) (29)
- Evaluation of Recipients of Positive and Negative Secondary Findings Evaluations in a Hybrid CLIA-Research Sequencing Pilot. (2018) (29)
- Hemodynamic effects of primary closure of omphalocele/gastroschisis in human newborns. (1986) (29)
- Replicating genotype – phenotype associations What constitutes replication of a genotype – phenotype association , and how best can it be achieved ? (2007) (29)
- The Emerging Importance of Genetics in Epidemiologic Research III. Bioinformatics and statistical genetic methods. (1999) (29)
- Model organisms contribute to diagnosis and discovery in the undiagnosed diseases network: current state and a future vision (2021) (29)
- Random digit dialing in Chicago CARDIA: comparison of individuals with unlisted and listed telephone numbers. (1992) (28)
- Ten-year trends in cigarette smoking among young adults, 1986-1996: the CARDIA study. Coronary Artery Risk Development In Young Adults. (1998) (28)
- Prevalence and associations of MRI-demonstrated brain infarcts in elderly subjects with a history of transient ischemic attack. The Cardiovascular Health Study. (1999) (28)
- Genotype Imputation of Metabochip SNPs Using a Study-Specific Reference Panel of ~4,000 Haplotypes in African Americans From the Women’s Health Initiative (2012) (28)
- Using the Data We Have: Improving Diversity in Genomic Research. (2019) (27)
- Blood Pressure Level and Outcomes in Adults Aged 65 and Older with Prior Ischemic Stroke (2006) (27)
- External Validity of the Cardiovascular Health Study: A Comparison With the Medicare Population (2009) (26)
- Obtaining informed consent for genetic studies: The multiethnic study of atherosclerosis. (2006) (26)
- The emerging importance of genetics in epidemiologic research. I. Basic concepts in human genetics and laboratory technology. (1999) (26)
- C-Reactive Protein and the 10-Year Incidence of Coronary Heart Disease in Older Men and Women (2005) (26)
- Leading the way to genomic medicine (2014) (26)
- Overtreatment and undertreatment of hypertension (1994) (25)
- In Retrospect: A decade of shared genomic associations (2017) (24)
- Aspirin Use and Incident Stroke in the Cardiovascular Health Study (1998) (24)
- Eligibility for cholesterol referral in community-dwelling older adults. The Cardiovascular Health Study. (1992) (24)
- A mechanism for controlled access to GWAS data: experience of the GAIN Data Access Committee. (2013) (24)
- Correlates of Sensitization to Blomia tropicalis and Dermatophagoides pteronyssinus in Asthma in Barbados (2003) (23)
- Taking Our Obligations to Research Participants Seriously: Disclosing Individual Results of Genetic Research (2006) (23)
- Evaluation of the Dinamap continuous blood pressure monitor. (1988) (23)
- A Prospective Analysis of Risk Factors for White Matter Disease in the Brain Stem (2003) (23)
- Predictors of falling cholesterol levels in older adults: the Cardiovascular Health Study. (2004) (23)
- Turning the pump handle: evolving methods for integrating the evidence on gene-disease association. (2007) (23)
- 27th Bethesda Conference: matching the intensity of risk factor management with the hazard for coronary disease events. Task Force 2. Clinical epidemiology: the conceptual basis for interpreting risk factors. (1996) (23)
- Current estrogen-progestin and estrogen replacement therapy in elderly women: association with carotid atherosclerosis. CHS Collaborative Research Group. Cardiovascular Health Study. (1997) (23)
- Research on coronary disease in women: political or scientific imperative? (1993) (23)
- Implementing genomics and pharmacogenomics in the clinic: The National Human Genome Research Institute's genomic medicine portfolio. (2016) (22)
- Age-adjusted death rates: consequences of the Year 2000 standard. (1999) (21)
- Sibling history of myocardial infarction or stroke and risk of cardiovascular disease in the elderly: the Cardiovascular Health Study. (2009) (20)
- Characteristics of undiagnosed diseases network applicants: implications for referring providers (2018) (19)
- A phenome-wide association study to discover pleiotropic effects of PCSK9, APOB, and LDLR (2019) (19)
- Efficacy of CVD Risk Factor Modification in a Lower-Middle Class Community in Pakistan: The Metroville Health Study (2003) (19)
- An autosomal dominant neurological disorder caused by de novo variants in FAR1 resulting in uncontrolled synthesis of ether lipids (2020) (18)
- Design and Conduct of Observational Studies and Clinical Trials (2002) (17)
- Erratum: Clinical Sequencing Exploratory Research Consortium: Accelerating Evidence-Based Practice of Genomic Medicine (American Journal of Human Genetics (2016) 98(6) (1067–1076) (S0002929716301069) (10.1016/j.ajhg.2016.04.011)) (2016) (17)
- Ischemic episodes in 24-h ambulatory electrocardiograms of elderly persons: the Cardiovascular Health Study. (1995) (16)
- Commentary: rare alleles, modest genetic effects and the need for collaboration. (2007) (16)
- Regional versus general anesthesia in high-risk surgical patients: the need for a clinical trial. (1989) (16)
- Multivariate analysis of factors associated with unplanned admission in 'outpatient' ophthalmic surgery. (1988) (16)
- Spirometry reference values for healthy elderly blacks. The Cardiovascular Health Study Research Group. (1996) (15)
- Sex differences in heritability of sensitization to Blomia tropicalis in asthma using regression of offspring on midparent (ROMP) methods (2003) (15)
- Generalizability of Polygenic Risk Scores for Breast Cancer Among Women With European, African, and Latinx Ancestry (2021) (15)
- Patterns on cranial magnetic resonance imaging in elderly people and vascular disease outcomes. (2001) (14)
- Research Directions in Genetic Predispositions to Stevens–Johnson Syndrome / Toxic Epidermal Necrolysis (2018) (14)
- Concordance between Research Sequencing and Clinical Pharmacogenetic Genotyping in the eMERGE-PGx Study. (2017) (14)
- Pharmacogenomics of HIV Therapy: Summary of a Workshop Sponsored by the National Institute of Allergy and Infectious Diseases (2011) (14)
- Diabetes, gender, and left ventricular structure in African-Americans: the atherosclerosis risk in communities study (2006) (13)
- Changes over time in blood lipids and their correlates in Polish rural and urban populations: the Poland-United States Collaborative Study in cardiopulmonary disease epidemiology. (1997) (13)
- Incidental genetic findings in randomized clinical trials: recommendations from the Genomics and Randomized Trials Network (GARNET) (2013) (13)
- Workshop proceedings: GWAS summary statistics standards and sharing (2021) (13)
- Incidence and predictors of coronary heart disease among older African Americans--the Cardiovascular Health Study. (2001) (13)
- The International Hundred Thousand Plus Cohort Consortium: integrating large-scale cohorts to address global scientific challenges (2020) (13)
- Study designs to enhance identification of genetic factors in healthy aging. (2007) (12)
- Commonalities across computational workflows for uncovering explanatory variants in undiagnosed cases (2021) (12)
- Progression of Magnetic Resonance Imaging-Defined Brain Vascular Disease Predicts Vascular Events in Elderly: The Cardiovascular Health Study (2011) (12)
- Variation and temporal trends in the use of diagnostic testing during hospitalization for acute myocardial infarction by age, gender, race, and geography (the Atherosclerosis Risk In Communities Study). (2008) (12)
- Should all babies have their genome sequenced at birth? (2021) (12)
- Clinical sites of the Undiagnosed Diseases Network: Unique contributions to genomic medicine and science (2020) (12)
- Biorepositories--at the bleeding edge. (2008) (11)
- Risk of Congestive Heart Failure in an Elderly Population Treated with Peripheral Alpha‐1 Antagonists (2004) (11)
- Constitutional, biochemical and lifestyle correlates of fibrinogen and factor VII activity in Polish urban and rural populations. (1998) (11)
- Potential problems with random zero sphygmomanometer (1990) (10)
- Opposing national stroke mortality trends in Poland and for African Americans and whites in the United States, 1968 to 1994. (1998) (10)
- Return of secondary findings in genomic sequencing: Military implications (2018) (9)
- Biallelic MADD variants cause a phenotypic spectrum ranging from developmental delay to a multisystem disorder. (2020) (9)
- Classification Accuracy of Electrocardiographic Criteria for Left Ventricular Hypertrophy in Normal Weight and Overweight Older Adults (1996) (8)
- Incorporating Whole-Genome Sequencing Into Primary Care: Falling Barriers and Next Steps (2017) (8)
- Race and education in relation to stopping smoking in the US: the CARDIA study (1993) (8)
- Clinical Sequencing Exploratory Research Consortium: Accelerating Evidence-Based Practice of Genomic Medicine. (2016) (7)
- Variants in PRKAR1B cause a neurodevelopmental disorder with autism spectrum disorder, apraxia, and insensitivity to pain (2020) (7)
- Arrhythmia Variant Associations and Reclassifications in the eMERGE-III Sequencing Study (2021) (7)
- The IGNITE network: a model for genomic medicine implementation and research (2015) (7)
- UK Biobank debuts as a powerful resource for genomic research (2018) (7)
- Pulmonary function testing in population-based studies. (1997) (7)
- Genomic Medicine Year in Review: 2019. (2019) (7)
- Unusual heterogeneity of circulating prolactin in an acromegalic (1981) (6)
- The new population standard for age-adjusting death rates. (2000) (6)
- Handgrip strength afterthe blalock‐taussig shunt: 14 to 34 year follow‐up (1988) (6)
- Planning and implementation of a cardiovascular prevention strategy in a lower middle class community in Pakistan - a preliminary report. (2000) (5)
- Associations of Genetically Predicted Lp(a) (Lipoprotein [a]) Levels With Cardiovascular Traits in Individuals of European and African Ancestry (2021) (5)
- Genome-and Phenome-Wide Analysis of Cardiac Conduction Identifies Markers of Arrhythmia Risk Running title : Ritchie et al . ; QRS GWAS and PheWAS in electronic records (2013) (5)
- Magnetic Resonance Imaging characteristics in case of TOR1AIP1 muscular dystrophy. (2019) (5)
- Correction: Phenotypic expansion of CACNA1C-associated disorders to include isolated neurological manifestations (2021) (5)
- Assessing and managing risk when sharing aggregate genetic variant data (2011) (4)
- Coronary calcium, race, and genes. (2002) (4)
- Gender-Related Risk Factors for Ischemic Heart Disease (2004) (4)
- Prevalence and Associations of MRI-Demonstrated Brain Infarcts in Elderly Subjects With a History of Transient Ischemic Attack (1999) (4)
- One is the loneliest number: genotypic matchmaking using the electronic health record (2021) (4)
- Clinical implementation of genomic medicine: the importance of global collaboration (2016) (3)
- Erratum: De Novo Variants in WDR37 Are Associated with Epilepsy, Colobomas, Dysmorphism, Developmental Delay, Intellectual Disability, and Cerebellar Hypoplasia (The American Journal of Human Genetics (2019) 105(2) (413–424), (S0002929719302393), (10.1016/j.ajhg.2019.06.014)) (2019) (3)
- Genomic Medicine Year in Review: 2020. (2020) (3)
- Vehement agreement on new models? (2013) (3)
- Identification of rare-disease genes using blood transcriptome sequencing and large control cohorts (2019) (3)
- The ACMG SF v3.0 gene list increases returnable variant detection by 22% when compared with v2.0 in the ClinSeq cohort. (2021) (3)
- MYOCARDIAL ISCHEMIA MAY BE MORE COMMON WITH REGIONAL THAN WITH GENERAL ANESTHESIA IN HIGH RISK PATIENTS (1986) (2)
- Genomic medicine year in review: 2021. (2021) (2)
- CHAPTER 16 – Design and Conduct of Observational Studies and Clinical Trials (2007) (2)
- Disclosing Individual Genetic Results to Research Participants (2012) (2)
- Cardiovascular mortality and risk factors: Is Poland repeating the US experience of 30 years ago? (2005) (2)
- Cardiac Arrhythimas on 24-h Ambulatory Electrocardiography hn Older Women and Men: The Cardiovascular Health Study (2016) (1)
- Comment on “Multidimensional Results Reporting to Participants in Genomic Studies: Getting It Right” (2011) (1)
- Clinical Investigation and Reports Ankle-Arm Index as a Marker of Atherosclerosis in the Cardiovascular Health Study (2005) (1)
- Fish consumption and stroke risk (2005) (1)
- 1 Office of Population Genomics, National Human Geno me Research Institute, National Institutes of (2011) (1)
- Are Associated with Erythrocyte Sedimentation Rate (2011) (1)
- Counterpoint: "streamlined" does not mean simple. (2013) (1)
- Neurologic correlates of infarction-like lesion location on magnetic resonance imaging in the cardiovascular health study (2000) (1)
- Returning integrated genomic risk and clinical recommendations: the eMERGE study. (2023) (1)
- Correction to: An autosomal dominant neurological disorder caused by de novo variants in FAR1 resulting in uncontrolled synthesis of ether lipids (2021) (1)
- Case-control and cohort studies in the age of genome-wide associations (2009) (1)
- Phenotypic expansion of CACNA1C-associated disorders to include isolated neurological manifestations (2021) (1)
- Incidental genetic findings in randomized clinical trials: recommendations from the Genomics and Randomized Trials Network (GARNET) (2013) (1)
- A resource of lipidomics and metabolomics data from individuals with undiagnosed diseases (2021) (1)
- Arrhythmia Risk Genome-and Phenome-Wide Analyses of Cardiac Conduction Identifies Markers of (2013) (1)
- Unrecognized myocardial infarction. (2001) (1)
- Older Adults (A Report from the Cardiovascular Health Study) (1996) (0)
- 292 A Genome-Wide Association Study of Spontaneous Preterm Delivery (2010) (0)
- Generalizability of Polygenic Risk Scores for Breast Cancer in the Multiethnic eMERGE Study (2020) (0)
- Clinical trials and epidemiological studies. (2005) (0)
- Abstract 1905: Intrinsic Contribution of Gender and Ethnicity to Normal Ankle-Brachial Index Values: The Multi-Ethnic Study of Atherosclerosis (2006) (0)
- 133 Evidence of heritability of the common form of atrial fibrillation (2005) (0)
- SCANNING THE PHENOME TO UNCOVER PLEIOTROPIC EFFECTS OF PCSK9 (2017) (0)
- Funding: CMSisfunded bytheMedical Research Council. Conflict ofinterest: Theauthors areinvolved inastudy of theprevalence ofatrial fibrillation andofindications and contraindications fortreatment withwarfarin, whichis funded bytheStroke Association. (1995) (0)
- Sex- and Race-RelatedDifferencesin Liver-Associated SerumChemistryTests in YoungAdultsin the CARDIAStudy (1992) (0)
- A New Annual Feature of AJHG: Genomic Medicine Year in Review (2019) (0)
- Abstract 14663: High Rate of Arrhythmia Diagnoses Following Return of Pathogenic/likely Pathogenic Variants in an Unselected Population (2020) (0)
- Letter to the Editor (2005) (0)
- Women’s Health and Menopause Epidemiology: The USA Experience (1999) (0)
- Public and Population Health Genomics (2016) (0)
- The riddle of intergenic disease-associated loci (2012) (0)
- Bi-allelic ATG4D variants are associated with a neurodevelopmental disorder characterized by speech and motor impairment (2023) (0)
- Validity of reported genetic risk factors for acute coronary syndrome. (2007) (0)
- PREVENTIVE CARDIOLOGY Methodology of Planning of Cardiovascular Disease Risk Factor Modification in A lower-middle Class Urban Community in Pakistan, Study Protocol (2012) (0)
- Familial Hypercholesterolemia in the Electronic Medical Records and Genomics Network: Prevalence, Penetrance, Cardiovascular Risk, and Outcomes After Return of Results (2023) (0)
- Pathogenic variants in arteriopathy genes detected in a targeted sequencing study: Penetrance and 1-year outcomes after return of results. (2022) (0)
- Stakeholder Engagement Workshop (2015) (0)
- Genomic Medicine Year in Review: 2022. (2022) (0)
- Development of Competency-based Online Genomic Medicine Training (COGENT). (2022) (0)
- Reviewer Acknowledgment (2008) (0)
- Silent Brain MRI Infarcts and Subsequent Stroke Type In the Cardiovascular health Study (2000) (0)
- Consistency of genome-wide associations across major ancestral groups (2011) (0)
- Abstract P225: African American LDL-C GWAS Reveals a Strong Protective SNP Association in APOE; The eMERGE Study (2012) (0)
- UK Biobank debuts as a powerful resource for genomic research (2018) (0)
- Characteristics and Baseline Clinical Predictors of Future Fatal Versus Nonfatal Coronary Heart Disease Events in Older Adults The Cardiovascular Coronary Heart Disease (2006) (0)
- Abstract 050: Fine-mapping and Bioinformatics Characterization of QT Interval Loci in African Americans: The Population Architecture Using Genomics and Epidemiology (PAGE) Study (2012) (0)
- novel drugs that activate apoptosis in selected cell popula- tions and use these compounds to limit viral replication? (2006) (0)
- VarSight: prioritizing clinically reported variants with binary classification algorithms (2019) (0)
- Cardiovascular Death and Cancer Death—Competing Risk? Drs. Nabel and Braunwald 1 have ele- (2012) (0)
- Bi-allelic variants in INTS11 are associated with a complex neurological disorder. (2023) (0)
- Estrogen replacement therapy and cardiovascular events: the cardiovascular health study (2002) (0)
- Abstract SY32-02: Genetic architecture of cancer and other complex diseases: Lessons learned and future directions (2010) (0)
- Predictors of falling cholesterol levels in older adults: (2001) (0)
- Practice Patterns After Return of Rare Variants Associated With Cardiomyopathy in the Electronic Medical Records and Genomics Network. (2021) (0)
- Participation in a national diagnostic research study: assessing the patient experience (2023) (0)
- Lung Function and Pulmonary Regurgitation Limit Exercise Capacity In Postoperative Tetralogy of Fallot treadmill and rest two-From (2016) (0)
- A comprehensive iterative approach is highly effective in diagnosing individuals who are exome negative (2018) (0)
- A phenome-wide association study to discover pleiotropic effects of PCSK9, APOB, and LDLR (2019) (0)
- YEAR IN REVIEW Genomic Medicine Year in Review: 2020 (2020) (0)
- Abstract MP076: Role of the Human Metabolome in Incident Heart Failure among African Americans (AAs) from the Atherosclerosis Risk in Communities (ARIC) Study (2012) (0)
- OP059: Clinical impact of a targeted pharmacogenomic assessment within a cohort of individuals with suspected inborn errors of immunity (2022) (0)
- Blood Pressure Response During Treadmill Testing as a Risk Factor for New-Onset Hypertension (1999) (0)
- Abstract 13242: Complement Receptor 1 Gene Variants are Associated With Erythrocyte Sedimentation Rate (2011) (0)
- 885-4 The severity of mitral annular calcification is associated with prevalent cardiovascular disease in the elderly: The cardiovascular health study (2004) (0)
- Abstract 15209: LPA Variants Are Associated With Aortic Valve Stenosis, Heart Failure and Chronic Kidney Disease (2020) (0)
- Retinal Microvascular Signs Are Associated With Cognitive Impairment in Older People: The Cardiovascular Health Study (2006) (0)
- Hormone Replacement and Cardiovascular Disease in Older Women (1996) (0)
- The relationship between alcohol use and prevalence of infarcts on cranial magnetic resonance imaging in hypertensive and normotensive elderly subjects (1998) (0)
- A research agenda to support the development and implementation of genomics-based clinical informatics tools and resources (2022) (0)
- Lipoprotein Lipids inOlderPeople Results FromtheCardiovascular Health Study (2011) (0)
- Prevalence of Unknown Parental History of Disease in Either or Both Parents Prevalence of unknown history ( % ) Race Mother Father Both Disease group only only parents Hypertension Black (2005) (0)
- Genomics in Public and Population Health (2014) (0)
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