Tetsuo Noda
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Cell Biology
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Biology
Tetsuo Noda's Degrees
- PhD Biology University of Tokyo
- Masters Biochemistry University of Tokyo
- Bachelors Biochemistry University of Tokyo
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(Suggest an Edit or Addition)Tetsuo Noda's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Claudin-based tight junctions are crucial for the mammalian epidermal barrier (2002) (1393)
- Disruption of Adiponectin Causes Insulin Resistance and Neointimal Formation* (2002) (1382)
- A role for macrophage scavenger receptors in atherosclerosis and susceptibility to infection (1997) (1240)
- ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis (2001) (1186)
- Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice. (1998) (1126)
- Complex phenotype of mice lacking occludin, a component of tight junction strands. (2000) (1123)
- Placental defect and embryonic lethality in mice lacking hepatocyte growth factor/scatter factor (1995) (1046)
- Adiponectin stimulates AMP-activated protein kinase in the hypothalamus and increases food intake. (2007) (776)
- Altered microtubule organization in small-calibre axons of mice lacking tau protein (1994) (738)
- Inflammasome Activation of Cardiac Fibroblasts Is Essential for Myocardial Ischemia/Reperfusion Injury (2011) (690)
- Rapid colorectal adenoma formation initiated by conditional targeting of the Apc gene. (1997) (600)
- Occludin-deficient Embryonic Stem Cells Can Differentiate into Polarized Epithelial Cells Bearing Tight Junctions (1998) (570)
- Epithelial-mesenchymal transition spectrum quantification and its efficacy in deciphering survival and drug responses of cancer patients (2014) (535)
- A Role for Hematopoietic Stem Cells in Promoting Angiogenesis (2000) (528)
- Loss of cerebellar Purkinje cells in aged mice homozygous for a disrupted PrP gene (1996) (493)
- Ataxia and epileptic seizures in mice lacking type 1 inositol 1,4,5-trisphosphate receptor (1996) (452)
- Excitation-contraction uncoupling and muscular degeneration in mice lacking functional skeletal muscle ryanodine-receptor gene (1994) (370)
- Involvement of Flt-1 tyrosine kinase (vascular endothelial growth factor receptor-1) in pathological angiogenesis. (2001) (365)
- Impairment of Antigen-Presenting Cell Function in Mice Lacking Expression of Ox40 Ligand (2000) (344)
- RNA-binding protein Musashi family: Roles for CNS stem cells and a subpopulation of ependymal cells revealed by targeted disruption and antisense ablation (2002) (341)
- Pioglitazone Ameliorates Insulin Resistance and Diabetes by Both Adiponectin-dependent and -independent Pathways* (2006) (322)
- Negative Regulation of BMP/Smad Signaling by Tob in Osteoblasts (2000) (314)
- Role of hepatic STAT3 in brain-insulin action on hepatic glucose production. (2006) (308)
- IP3 Receptor Types 2 and 3 Mediate Exocrine Secretion Underlying Energy Metabolism (2005) (308)
- Defect in Synaptic Vesicle Precursor Transport and Neuronal Cell Death in KIF1A Motor Protein–deficient Mice (1998) (302)
- Renal carcinogenesis, hepatic hemangiomatosis, and embryonic lethality caused by a germ-line Tsc2 mutation in mice. (1999) (280)
- Deficiency of zonula occludens-1 causes embryonic lethal phenotype associated with defected yolk sac angiogenesis and apoptosis of embryonic cells. (2008) (270)
- Kinetochore stretching inactivates the spindle assembly checkpoint (2009) (255)
- Apollon ubiquitinates SMAC and caspase-9, and has an essential cytoprotection function (2004) (251)
- Lack of acrosome formation in mice lacking a Golgi protein, GOPC (2002) (248)
- G protein-coupled cholecystokinin-B/gastrin receptors are responsible for physiological cell growth of the stomach mucosa in vivo. (1996) (248)
- A germ-line Tsc1 mutation causes tumor development and embryonic lethality that are similar, but not identical to, those caused by Tsc2 mutation in mice (2001) (246)
- bcl-2 deficiency in mice leads to pleiotropic abnormalities: accelerated lymphoid cell death in thymus and spleen, polycystic kidney, hair hypopigmentation, and distorted small intestine. (1995) (245)
- Brn-1 and Brn-2 share crucial roles in the production and positioning of mouse neocortical neurons. (2002) (241)
- Insulin receptor substrate 2 plays a crucial role in beta cells and the hypothalamus. (2004) (240)
- Autoimmune disorders associated with gain of function of the intracellular sensor MDA5. (2014) (219)
- Dynamic functional relay between insulin receptor substrate 1 and 2 in hepatic insulin signaling during fasting and feeding. (2008) (216)
- PDK1 signaling in oocytes controls reproductive aging and lifespan by manipulating the survival of primordial follicles. (2009) (216)
- Altered cochlear fibrocytes in a mouse model of DFN3 nonsyndromic deafness. (1999) (214)
- The RNA-binding protein HuD regulates neuronal cell identity and maturation. (2005) (205)
- ASC is essential for LPS‐induced activation of procaspase‐1 independently of TLR‐associated signal adaptor molecules (2004) (205)
- Mouse Zic1 Is Involved in Cerebellar Development (1998) (204)
- Ablation of PDK1 in pancreatic β cells induces diabetes as a result of loss of β cell mass (2006) (202)
- Hematopoiesis in the fetal liver is impaired by targeted mutagenesis of a gene encoding a non-DNA binding subunit of the transcription factor, polyomavirus enhancer binding protein 2/core binding factor. (1997) (201)
- Loss of claudin-15, but not claudin-2, causes Na+ deficiency and glucose malabsorption in mouse small intestine. (2011) (201)
- Megaintestine in claudin-15-deficient mice. (2008) (189)
- PKClambda in liver mediates insulin-induced SREBP-1c expression and determines both hepatic lipid content and overall insulin sensitivity. (2003) (186)
- Coordinated Ciliary Beating Requires Odf2-Mediated Polarization of Basal Bodies via Basal Feet (2012) (184)
- Biphasic Response of Pancreatic β-Cell Mass to Ablation of Tuberous Sclerosis Complex 2 in Mice (2008) (177)
- Inactivation of aPKCλ results in the loss of adherens junctions in neuroepithelial cells without affecting neurogenesis in mouse neocortex (2006) (176)
- Concomitant suppression of hyperlipidemia and intestinal polyp formation in Apc-deficient mice by peroxisome proliferator-activated receptor ligands. (2003) (169)
- Normal Development of Mice and Unimpaired Cell Adhesion/Cell Motility/Actin-based Cytoskeleton without Compensatory Up-regulation of Ezrin or Radixin in Moesin Gene Knockout* (1999) (169)
- Synapsin I deficiency results in the structural change in the presynaptic terminals in the murine nervous system (1995) (168)
- Transgenic mouse model of kidney disease: Insertional inactivation of ubiquitously expressed gene leads to nephrotic syndrome (1990) (167)
- Requirement of Runx1/AML1/PEBP2αB for the generation of haematopoietic cells from endothelial cells (2001) (164)
- Methionine adenosyltransferase II serves as a transcriptional corepressor of Maf oncoprotein. (2011) (162)
- MALDI-based imaging mass spectrometry revealed abnormal distribution of phospholipids in colon cancer liver metastasis. (2007) (161)
- A Genetic Approach to Visualization of Multisynaptic Neural Pathways Using Plant Lectin Transgene (1999) (159)
- Phylogenetic conservation of a limb-specific, cis-acting regulator of Sonic hedgehog (Shh) (2004) (157)
- Ablation of PDK1 in pancreatic beta cells induces diabetes as a result of loss of beta cell mass. (2006) (150)
- Plasmacytic Transcription Factor Blimp-1 Is Repressed by Bach2 in B Cells* (2006) (148)
- Inflammasome Activation by Mitochondrial Oxidative Stress in Macrophages Leads to the Development of Angiotensin II–Induced Aortic Aneurysm (2014) (147)
- Transposition of the Tol2 element, an Ac-like element from the Japanese medaka fish Oryzias latipes, in mouse embryonic stem cells. (2004) (147)
- Crucial roles of Brn1 in distal tubule formation and function in mouse kidney (2003) (146)
- AML1(−/−) embryos do not express certain hematopoiesis-related gene transcripts including those of the PU.1 gene (1998) (138)
- Separation of killing and tumorigenic effects of an alkylating agent in mice defective in two of the DNA repair genes. (1998) (133)
- Oligo-astheno-teratozoospermia in mice lacking Cnot7, a regulator of retinoid X receptor beta (2004) (129)
- Delayed Development of Nervous System in Mice Homozygous for Disrupted Microtubule-associated Protein 1B (MAP1B) Gene (1997) (128)
- Altered emotional behavioral responses in mice lacking brain‐type fatty acid‐binding protein gene (2006) (127)
- Whole-exome sequencing of human pancreatic cancers and characterization of genomic instability caused by MLH1 haploinsufficiency and complete deficiency. (2012) (118)
- High accumulation of oxidative DNA damage, 8-hydroxyguanine, in Mmh/Ogg1 deficient mice by chronic oxidative stress. (2002) (117)
- Fas ligand-mediated exocrinopathy resembling Sjögren's syndrome in mice transgenic for IL-10. (1999) (116)
- PAR3 is essential for cyst-mediated epicardial development by establishing apical cortical domains (2006) (113)
- NLRP3 Regulates Neutrophil Functions and Contributes to Hepatic Ischemia–Reperfusion Injury Independently of Inflammasomes (2014) (113)
- Genetic analysis of Pten and Tsc2 functional interactions in the mouse reveals asymmetrical haploinsufficiency in tumor suppression. (2005) (113)
- Mice lacking a transcriptional corepressor Tob are predisposed to cancer. (2003) (111)
- VEGF receptor 1 signaling is essential for osteoclast development and bone marrow formation in colony-stimulating factor 1-deficient mice. (2005) (108)
- Hepatocyte nuclear factor 1β controls nephron tubular development (2013) (108)
- Human glycyl-tRNA synthetase. Wide divergence of primary structure from bacterial counterpart and species-specific aminoacylation. (1994) (105)
- Targeted disruption of the homeobox transcription factor Bapx1 results in lethal skeletal dysplasia with asplenia and gastroduodenal malformation (2000) (104)
- The complete removal of cohesin from chromosome arms depends on separase (2007) (99)
- The Corepressor mSin3A Regulates Phosphorylation-Induced Activation, Intranuclear Location, and Stability of AML1 (2004) (98)
- Subcellular localization of the APC protein: immunoelectron microscopic study of the association of the APC protein with catenin. (1995) (98)
- Enamelin (Enam) is essential for amelogenesis: ENU-induced mouse mutants as models for different clinical subtypes of human amelogenesis imperfecta (AI). (2005) (92)
- Coexpression of MUC16 and mesothelin is related to the invasion process in pancreatic ductal adenocarcinoma (2012) (91)
- Pancreatic β-Cell Failure Mediated by mTORC1 Hyperactivity and Autophagic Impairment (2014) (90)
- Molecular characterization of ENU mouse mutagenesis and archives. (2005) (89)
- Bach1 inhibits oxidative stress–induced cellular senescence by impeding p53 function on chromatin (2008) (85)
- Identification of two distinct elements in the long terminal repeat of HTLV‐I responsible for maximum gene expression. (1987) (84)
- Anti-Inflammatory Activity of PYNOD and Its Mechanism in Humans and Mice (2010) (84)
- Id4, a New Candidate Gene for Senile Osteoporosis, Acts as a Molecular Switch Promoting Osteoblast Differentiation (2010) (84)
- Identification of a PDZ domain containing Golgi protein, GOPC, as an interaction partner of frizzled. (2001) (81)
- Zic1 regulates the patterning of vertebral arches in cooperation with Gli3 (1999) (78)
- [Preparation of the gene targeted knockout mice for human premature aging diseases, Werner syndrome, and Rothmund-Thomson syndrome caused by the mutation of DNA helicases]. (2002) (78)
- The selective continued linkage of centromeres from mitosis to interphase in the absence of mammalian separase (2006) (78)
- Apoptosis in neural crest cells by functional loss of APC tumor suppressor gene (2001) (77)
- Inositol monophosphatase activity from the Escherichia coli suhB gene product (1995) (75)
- PKCλ regulates glucose-induced insulin secretion through modulation of gene expression in pancreatic β cells (2005) (75)
- Inhibitory effects of mofezolac, a cyclooxygenase-1 selective inhibitor, on intestinal carcinogenesis. (2002) (74)
- The study using wild-type and Ogg1 knockout mice exposed to potassium bromate shows no tumor induction despite an extensive accumulation of 8-hydroxyguanine in kidney DNA. (2006) (73)
- Human Lysyl-tRNA Synthetase Accepts Nucleotide 73 Variants and Rescues Escherichia coli Double-defective Mutant* (1997) (72)
- A series of maturity onset diabetes of the young, type 2 (MODY2) mouse models generated by a large-scale ENU mutagenesis program. (2004) (72)
- PRMT5, a Novel TRAIL Receptor-Binding Protein, Inhibits TRAIL-Induced Apoptosis via Nuclear Factor-κB Activation (2009) (72)
- Implementation of the modified-SHIRPA protocol for screening of dominant phenotypes in a large-scale ENU mutagenesis program (2005) (71)
- Function of Atypical Protein Kinase C λ in Differentiating Photoreceptors Is Required for Proper Lamination of Mouse Retina (2005) (71)
- Cell proliferation in liver of Mmh/Ogg1-deficient mice enhances mutation frequency because of the presence of 8-hydroxyguanine in DNA. (2003) (71)
- MAGI-3 is involved in the regulation of the JNK signaling pathway as a scaffold protein for frizzled and Ltap (2004) (70)
- An Essential Role of the Universal Polarity Protein, aPKCλ, on the Maintenance of Podocyte Slit Diaphragms (2009) (70)
- A series of ENU-induced single-base substitutions in a long-range cis-element altering Sonic hedgehog expression in the developing mouse limb bud. (2007) (70)
- Identification of a transforming gene of human papillomavirus type 16 (1989) (69)
- Combined effects of cyclooxygenase‐1 and cyclooxygenase‐2 selective inhibitors on intestinal tumorigenesis in adenomatous polyposis coli gene knockout mice (2004) (69)
- Analysis on the phenotype of E-FABP-gene knockout mice (2002) (69)
- A novel dominant-negative mutation in Gdf5 generated by ENU mutagenesis impairs joint formation and causes osteoarthritis in mice. (2007) (68)
- Activated macrophages are responsible for the tumor‐inhibitory effect in mice receiving intravenous injection of OK‐432 (1984) (67)
- Activated β-Catenin in Foxp3+ Regulatory T cells Links Inflammatory Environments to Autoimmunity (2018) (65)
- Perinatal Gjb2 gene transfer rescues hearing in a mouse model of hereditary deafness. (2015) (65)
- Altered water barrier function in epidermal-type fatty acid binding protein-deficient mice. (2002) (63)
- PDK-1/FoxO1 pathway in POMC neurons regulates Pomc expression and food intake. (2010) (62)
- ASC in renal collecting duct epithelial cells contributes to inflammation and injury after unilateral ureteral obstruction. (2014) (62)
- Clinically relevant molecular subtypes and genomic alteration-independent differentiation in gynecologic carcinosarcoma (2019) (62)
- Growth retardation in human cervical dysplasia-derived cell lines by beta-carotene through down-regulation of epidermal growth factor receptor. (1995) (61)
- Molecular mechanism of moderate insulin resistance in adiponectin-knockout mice. (2008) (61)
- Targeted Deletion of Both Thymidine Phosphorylase and Uridine Phosphorylase and Consequent Disorders in Mice (2002) (60)
- Nanosilica-induced placental inflammation and pregnancy complications: Different roles of the inflammasome components NLRP3 and ASC (2014) (60)
- Differential hepatic distribution of insulin receptor substrates causes selective insulin resistance in diabetes and obesity (2016) (59)
- Unique mechanisms of growth regulation and tumor suppression upon Apc inactivation in the pancreas (2007) (58)
- Clinical relevance of circulating tumor DNA assessed through deep sequencing in patients with metastatic colorectal cancer (2018) (57)
- Failure to assemble the peri-nuclear structures in GOPC deficient spermatids as found in round-headed spermatozoa. (2004) (57)
- Loss of Pdk1-Foxo1 Signaling in Myeloid Cells Predisposes to Adipose Tissue Inflammation and Insulin Resistance (2012) (56)
- Newly synthesized curcumin analog has improved potential to prevent colorectal carcinogenesis in vivo (2009) (56)
- Role of CCK-A Receptor for Pancreatic Function in Mice: A Study in CCK-A Receptor Knockout Mice (2002) (55)
- Factors Maintaining Normal Sperm Tail Structure During Epididymal Maturation Studied in Gopc−/− Mice1 (2007) (55)
- A metastatic signature in entire lung adenocarcinomas irrespective of morphological heterogeneity. (2007) (55)
- Distinct germline progenitor subsets defined through Tsc2–mTORC1 signaling (2015) (53)
- Rimonabant Ameliorates Insulin Resistance via both Adiponectin-dependent and Adiponectin-independent Pathways* (2009) (53)
- Combined effects of prostaglandin E receptor subtype EP1 and subtype EP4 antagonists on intestinal tumorigenesis in adenomatous polyposis coli gene knockout mice (2003) (53)
- Human cytoplasmic isoleucyl-tRNA synthetase: selective divergence of the anticodon-binding domain and acquisition of a new structural unit. (1994) (52)
- Conventional and array-based comparative genomic hybridization analyses of novel cell lines harboring HPV18 from glassy cell carcinoma of the uterine cervix. (2004) (51)
- PDK1 coordinates survival pathways and β-adrenergic response in the heart (2009) (51)
- Epigenetic Regulation of the Blimp-1 Gene (Prdm1) in B Cells Involves Bach2 and Histone Deacetylase 3* (2016) (51)
- Assembly of the cochlear gap junction macromolecular complex requires connexin 26. (2014) (50)
- Complement C1q-induced activation of β-catenin signalling causes hypertensive arterial remodelling (2015) (49)
- ASC-associated inflammation promotes cecal tumorigenesis in aryl hydrocarbon receptor-deficient mice. (2013) (49)
- Ablation of TSC2 Enhances Insulin Secretion by Increasing the Number of Mitochondria through Activation of mTORC1 (2011) (48)
- Conditional mutations of beta-catenin and APC reveal roles for canonical Wnt signaling in lens differentiation. (2009) (48)
- Lymphoid enhancer factor 1 makes cells resistant to transforming growth factor beta-induced repression of c-myc. (2003) (47)
- Energy metabolism and turnover are increased in mice lacking the cholecystokinin-B receptor. (2002) (46)
- Prevention of gastrointestinal tumors based on adenomatous polyposis coli gene mutation by dendritic cell vaccine. (2004) (46)
- Identification of Reliable Components in Multivariate Curve Resolution-Alternating Least Squares (MCR-ALS): a Data-Driven Approach across Metabolic Processes (2015) (45)
- A defect in a single allele of the Mlh1 gene causes dissociation of the killing and tumorigenic actions of an alkylating carcinogen in methyltransferase-deficient mice. (2000) (45)
- The coiled tail of the round-headed spermatozoa appears during epididymal passage in GOPC-deficient mice. (2004) (45)
- Achlorhydria by ezrin knockdown (2005) (43)
- Putative gene loci associated with carcinogenesis and metastasis of endocervical adenocarcinomas of uterus determined by conventional and array-based CGH. (2004) (43)
- IL12RB2 and ABCA1 Genes Are Associated with Susceptibility to Radiation Dermatitis (2008) (43)
- Inactivation of Apc perturbs mammary development, but only directly results in acanthoma in the context of Tcf-1 deficiency (2002) (42)
- Serial circulating tumour DNA analysis for locally advanced rectal cancer treated with preoperative therapy: prediction of pathological response and postoperative recurrence (2020) (42)
- TACC3 is required for the proper mitosis of sclerotome mesenchymal cells during formation of the axial skeleton (2007) (42)
- Detection of novel mutations in the gyrA gene of Staphylococcus aureus by nonradioisotopic single-strand conformation polymorphism analysis and direct DNA sequencing (1994) (41)
- Late-onset hearing loss in a mouse model of DFN3 non-syndromic deafness: morphologic and immunohistochemical analyses (2002) (41)
- Creation of libraries with long ORFs by polymerization of a microgene. (1997) (41)
- Carcinogenicity of dimethylarsinic acid in Ogg1‐deficient mice (2007) (40)
- Adenomatous Polyposis Coli Is Essential for Both Neuronal Differentiation and Maintenance of Adult Neural Stem Cells in Subventricular Zone and Hippocampus (2010) (40)
- Importance of CCK-A receptor for gallbladder contraction and pancreatic secretion: a study in CCK-A receptor knockout mice. (2001) (39)
- Disruption of Tacc3 function leads to in vivo tumor regression (2012) (38)
- Restoration of Glucokinase Expression in the Liver Normalizes Postprandial Glucose Disposal in Mice With Hepatic Deficiency of PDK1 (2007) (38)
- Inactivation of aPKCλ results in the loss of adherens junctions in neuroepithelial cells without affecting neurogenesis in mouse neocortex (2006) (37)
- ARF Tumor Suppressor Induces Mitochondria-dependent Apoptosis by Modulation of Mitochondrial Bcl-2 Family Proteins* (2003) (37)
- PDK1 Regulates Cell Proliferation and Cell Cycle Progression through Control of Cyclin D1 and p27Kip1 Expression* (2008) (34)
- Human Parvovirus B19 Transgenic Mice Become Susceptible to Polyarthritis1 (2004) (34)
- alpha-catenin-deficient F9 cells differentiate into signet ring cells. (1999) (33)
- Nucleic acid sensing by T cells initiates Th2 cell differentiation (2014) (33)
- Interferon‐γ Induction in Human Peripheral Blood Mononuclear Cells by OK‐432, a Killed Preparation of Streptococcus pyogenes (1986) (33)
- Isolation and characterization of NIH 3T3 cells expressing polyomavirus small T antigen (1986) (33)
- Targeted disruption of FSCN2 gene induces retinopathy in mice. (2005) (32)
- Molecular markers associated with lymph node metastasis in pancreatic ductal adenocarcinoma by genome‐wide expression profiling (2010) (32)
- Identification and characterization of new long conserved noncoding sequences in vertebrates (2008) (32)
- γ-Glutamyltranspeptidase (GGT)-Activatable Fluorescence Probe for Durable Tumor Imaging. (2020) (32)
- Enrichment of CLDN18‐ARHGAP fusion gene in gastric cancers in young adults (2019) (32)
- Cnot7‐Null Mice Exhibit High Bone Mass Phenotype and Modulation of BMP Actions (2007) (31)
- PDK1-Foxo1 in Agouti-Related Peptide Neurons Regulates Energy Homeostasis by Modulating Food Intake and Energy Expenditure (2011) (31)
- Human Glycyl-tRNA Synthetase (1994) (31)
- Synthesis of functional proteins by mixing peptide motifs. (2004) (31)
- A small compound targeting TACC3 revealed its different spatiotemporal contributions for spindle assembly in cancer cells (2014) (31)
- Genomic organization of the mouse Msh4 gene producing bicistronic, chimeric and antisense mRNA. (2004) (30)
- Enhanced gastric emptying of a liquid gastric load in mice lacking cholecystokinin-B receptor: a study of CCK-A,B, and AB receptor gene knockout mice (2004) (30)
- Maternal phosphatidylinositol 3‐kinase signalling is crucial for embryonic genome activation and preimplantation embryogenesis (2010) (30)
- Tysnd1 Deficiency in Mice Interferes with the Peroxisomal Localization of PTS2 Enzymes, Causing Lipid Metabolic Abnormalities and Male Infertility (2013) (30)
- Human alanyl-tRNA synthetase: conservation in evolution of catalytic core and microhelix recognition. (1995) (30)
- Introduction to the Japan Mouse Clinic at the RIKEN BioResource Center. (2009) (29)
- PKClambda regulates glucose-induced insulin secretion through modulation of gene expression in pancreatic beta cells. (2005) (29)
- TUFT1 interacts with RABGAP1 and regulates mTORC1 signaling (2018) (29)
- Isolation of a new type of human papillomavirus (HPV52b) with a transforming activity from cervical cancer tissue. (1988) (28)
- Activation of endothelial β-catenin signaling induces heart failure (2016) (27)
- Phenotypic characterization of a new Grin1 mutant mouse generated by ENU mutagenesis (2010) (27)
- On the role of periodism in the origin of proteins. (2002) (27)
- Lack of Cholecystokinin-A Receptor Enhanced Gallstone Formation: A Study in CCK-A Receptor Gene Knockout Mice (2003) (26)
- Requirement for 3-Phosphoinositide-dependent Kinase-1 (PDK-1) in Insulin-induced Glucose Uptake in Immortalized Brown Adipocytes* (2003) (24)
- Development and implementation of a database system to manage a large-scale mouse ENU-mutagenesis program (2004) (24)
- Impaired Motor Coordination in Mice Lacking Prion Protein (1998) (23)
- Disruption of cholecystokinin (CCK)-B receptor gene did not modify bile or pancreatic secretion or pancreatic growth: a study in CCK-B receptor gene knockout mice. (1999) (23)
- HOXB2, an adverse prognostic indicator for stage I lung adenocarcinomas, promotes invasion by transcriptional regulation of metastasis-related genes in HOP-62 non-small cell lung cancer cells. (2008) (23)
- Ethical concerns on sharing genomic data including patients’ family members (2018) (23)
- Distinct macroscopic structures developed from solutions of chemical compounds and periodic proteins (2003) (22)
- Odf2 haploinsufficiency causes a new type of decapitated and decaudated spermatozoa, Odf2-DDS, in mice (2019) (22)
- Administration of BMP2/7 in utero partially reverses Rubinstein-Taybi syndrome-like skeletal defects induced by Pdk1 or Cbp mutations in mice. (2012) (22)
- Cooperation of middle and small T antigens of polyomavirus in transformation of established fibroblast and epithelial-like cell lines (1987) (22)
- Identification of NIPSNAP1 as a Nocistatin-interacting Protein Involving Pain Transmission* (2012) (22)
- α-Catenin is essential in intestinal adenoma formation (2007) (22)
- Identifying Molecular Markers for Chemosensitivity to Gemcitabine in Pancreatic Cancer: Increased Expression of Interferon-Stimulated Gene 15 kd Is Associated With Intrinsic Chemoresistance (2010) (22)
- HOXB2 as a Novel Prognostic Indicator for Stage I Lung Adenocarcinomas (2007) (22)
- In Vitro Models of GJB2-Related Hearing Loss Recapitulate Ca2+ Transients via a Gap Junction Characteristic of Developing Cochlea (2016) (21)
- Role of ASC in the Mouse Model of Helicobacter pylori Infection (2009) (21)
- Different effects of oral administration of synthetic trypsin inhibitor on the pancreas between cholecystokinin-A receptor gene knockout mice and wild type mice. (2002) (20)
- Somatic chromosomal translocation between Ewsr1 and Fli1 loci leads to dilated cardiomyopathy in a mouse model (2015) (20)
- Expression of Pou3f3/Brn‐1 and its genomic methylation in developing auditory epithelium (2009) (20)
- Human asparaginyl-tRNA synthetase: molecular cloning and the inference of the evolutionary history of Asx-tRNA synthetase family. (1998) (20)
- Progression of the phenotype of transformed cells after growth stimulation of cells by a human papillomavirus type 16 gene function (1988) (20)
- Insulin- and Lipopolysaccharide-Mediated Signaling in Adipose Tissue Macrophages Regulates Postprandial Glycemia through Akt-mTOR Activation. (2020) (19)
- Appearance of an oocyte activation-related substance during spermatogenesis in mice and humans. (2010) (18)
- Beneficial innate signaling interference for antibacterial responses by a Toll-like receptor–mediated enhancement of the MKP-IRF3 axis (2013) (18)
- A monogenic dominant mutation in Rom1 generated by N-ethyl-N-nitrosourea mutagenesis causes retinal degeneration in mice (2010) (18)
- Rescue of embryonic lethality in hepatocyte growth factor/scatter factor knockout mice (2000) (17)
- Establishment and characterization of human cell lines from a serous papillary adenocarcinoma of the endometrium. (1994) (16)
- Moesin Is Not a Receptor for Measles Virus Entry into Mouse Embryonic Stem Cells (1998) (16)
- Alpha-catenin is essential in intestinal adenoma formation. (2007) (16)
- Abnormal sperm morphology caused by defects in Sertoli cells of Cnot7 knockout mice. (2004) (16)
- Oocyte activation ability correlates with head flatness and presence of perinuclear theca substance in human and mouse sperm. (2009) (15)
- Osteoporotic bone formation in mice lacking tob2; involvement of Tob2 in RANK ligand expression and osteoclasts differentiation (2008) (15)
- Transposition of the Tol 2 Element , an Ac-Like Element From the Japanese Medaka Fish Oryzias latipes , in Mouse Embryonic Stem Cells (2004) (14)
- Autonomous cure of damaged human intestinal epithelial cells by TLR2 and TLR4-dependent production of IL-22 in response to Spirulina polysaccharides. (2013) (14)
- Comparative Analysis of Patient-Matched PDOs Revealed a Reduction in OLFM4-Associated Clusters in Metastatic Lesions in Colorectal Cancer (2021) (14)
- Ablation of 3-phosphoinositide-dependent protein kinase 1 (PDK1) in vascular endothelial cells enhances insulin sensitivity by reducing visceral fat and suppressing angiogenesis. (2012) (13)
- Tracking mouse visual pathways with WGA transgene (2003) (13)
- Development of detection method for novel fusion gene using GeneChip exon array (2014) (13)
- Identification of mycobacteria by nonradioisotopic single-strand conformation polymorphism analysis. (1995) (12)
- Prediction of the therapeutic response to paclitaxel by gene expression profiling in neoadjuvant chemotherapy for breast cancer. (2004) (12)
- Deoxyinosine triphosphate induces MLH1/PMS2- and p53-dependent cell growth arrest and DNA instability in mammalian cells (2016) (12)
- IFN/STAT signaling controls tumorigenesis and the drug response in colorectal cancer (2019) (12)
- Two distinct tumorigenic processes in endometrial endometrioid adenocarcinoma. (2019) (12)
- TP53 and OSBPL10 alterations in diffuse large B-cell lymphoma: prognostic markers identified via exome analysis of cases with extreme prognosis (2018) (11)
- Prevalence of disease-causing genes in Japanese patients with BRCA1/2-wildtype hereditary breast and ovarian cancer syndrome (2020) (11)
- Enhanced stability of hippocampal place representation caused by reduced magnesium block of NMDA receptors in the dentate gyrus (2014) (11)
- Prevalence of disease-causing genes in Japanese patients with BRCA1/2-wildtype hereditary breast and ovarian cancer syndrome. (2020) (10)
- Cancer-Specific Targeting of Taurine-Upregulated Gene 1 Enhances the Effects of Chemotherapy in Pancreatic Cancer (2021) (10)
- Regulation of Small Intestinal Epithelial Homeostasis by Tsc2-mTORC1 Signaling. (2019) (10)
- Correction: IL12RB2 and ABCA1 Genes Are Associated with Susceptibility to Radiation Dermatitis (2010) (9)
- ENU mutagenesis screening for dominant behavioral mutations based on normal control data obtained in home-cage activity, open-field, and passive avoidance tests. (2010) (9)
- Embryonic lethality in mice lacking mismatch-specific thymine DNA glycosylase is partially prevented by DOPS, a precursor of noradrenaline. (2012) (9)
- Novel mouse model for Gardner syndrome generated by a large‐scale N‐ethyl‐N‐nitrosourea mutagenesis program (2013) (9)
- Translated products of tandem microgene repeats exhibit diverse properties also seen in natural proteins. (2003) (9)
- Somatic mutations of the PTEN/NMAC1 gene associated with frequent chromosomal loss detected using comparative genomic hybridization in endometrial cancer. (2001) (9)
- Deficiency of the Erc/mesothelin gene ameliorates renal carcinogenesis in Tsc2 knockout mice (2011) (9)
- Deficiency of Transcription Factor Brn4 Disrupts Cochlear Gap Junction Plaques in a Model of DFN3 Non-Syndromic Deafness (2014) (8)
- Suppression of intestinal tumors by targeting the mitotic spindle of intestinal stem cells (2016) (8)
- Mouse models for ROS1-fusion-positive lung cancers and their application to the analysis of multikinase inhibitor efficiency. (2016) (7)
- Novel retinoblastoma mutation abrogating the interaction to E2F2/3, but not E2F1, led to selective suppression of thyroid tumors (2014) (7)
- PRMT 5 , a Novel TRAIL Receptor-Binding Protein , Inhibits TRAIL-Induced Apoptosis via Nuclear Factor-κ B Activation (2009) (7)
- Mice Mutation in Tsc 2 Embryonic Lethality Caused by a GermLine Renal Carcinogenesis , Hepatic Hemangiomatosis , and Updated (1999) (7)
- Genomic determinants impacting the clinical outcome of mogamulizumab treatment for adult T-cell leukemia/lymphoma (2022) (6)
- Regulation of colonic epithelial cell homeostasis by mTORC1 (2020) (6)
- β-cateninC429S mice exhibit sterility consequent to spatiotemporally sustained Wnt signalling in the internal genitalia (2014) (6)
- Growth Retardation in Human Cervical Dysplasia-Derived Cell Lines by β-Carotene (1997) (6)
- PDK-1 / FoxO 1 pathway in POMC neurons regulates Pomc expression and food intake (2010) (6)
- Immunogenomic landscape of gynecologic carcinosarcoma. (2020) (6)
- Tysnd 1 Deficiency in Mice Interferes with the Peroxisomal Localization of PTS 2 Enzymes , Causing Lipid Metabolic Abnormalities and Male Infertility (2018) (5)
- Polymorphisms in the promoter region of the porcine antiviral MX1 and MX2 genes. (2008) (5)
- Deformation of the Outer Hair Cells and the Accumulation of Caveolin-2 in Connexin 26 Deficient Mice (2015) (5)
- Cell Death in Thymus and Spleen, Polycystic Kidney, Hair Hypopigmentation, and Distorted Small Intestine1 (1995) (5)
- Targeting Podoplanin for the Treatment of Osteosarcoma (2022) (5)
- A novel genetic system to isolate a dominant negative effector on DNA-binding activity of Oct-2. (1997) (5)
- Characterization of folding pathways of the type-1 and type-2 periplasmic binding proteins MglB and ArgT. (2003) (5)
- Guide oligonucleotide-dependent DNA linkage that facilitates controllable polymerization of microgene blocks. (2002) (5)
- Contribution of insulin signaling to the regulation of pancreatic beta-cell mass during the catch-up growth period in a low birth weight mouse model (2014) (5)
- OCAM Regulates Embryonic Spinal Cord Stem Cell Proliferation by Modulating ErbB2 Receptor (2015) (4)
- Common Peak Approach Using Mass Spectrometry Data Sets for Predicting the Effects of Anticancer Drugs on Breast Cancer (2007) (4)
- Probing the tumorigenic potential of genetic interactions reconstituted in murine fallopian tube organoids (2021) (4)
- Tumor-Infiltrating PD-1+ Immune Cell Density is Associated with Response to Neoadjuvant Chemoradiotherapy in Rectal Cancer. (2022) (4)
- Integrative genome‐wide analyses reveal the transcriptional aberrations in Japanese esophageal squamous cell carcinoma (2021) (3)
- SDOP-DB: a comparative standardized-protocol database for mouse phenotypic analyses (2010) (3)
- Human Parvovirus B 19 Transgenic Mice Become Susceptible to Polyarthritis 1 (2004) (3)
- GRHL2 motif is associated with intratumor heterogeneity of cis-regulatory elements in luminal breast cancer (2022) (3)
- Immunogenic characteristics of microsatellite instability‐low esophagogastric junction adenocarcinoma based on clinicopathological, molecular, immunological and survival analyses (2020) (3)
- Novel allelic mutations in murine Serca2 induce differential development of squamous cell tumors. (2016) (3)
- Pathogenicity assessment of variants for breast cancer susceptibility genes based on BRCAness of tumor sample (2021) (2)
- High incidence of gallstone formation in CCK-A receptor gene knockout mice: Essential role of CCK-A receptor in gallstone formation (2001) (2)
- γ‐Glutamyltranspeptidase (GGT)‐Activatable Fluorescence Probe for Durable Tumor Imaging (2020) (2)
- Prospective randomized phase II study determines the clinical usefulness of genetic biomarkers for sensitivity to primary chemotherapy with paclitaxel in breast cancer (2011) (2)
- Author Correction: Activation of endothelial β-catenin signaling induces heart failure (2018) (2)
- Developmental Mutations Generated by Retroviral Insertional Mutagenesis (1992) (2)
- Podocyte-specific deletion of tubular sclerosis complex 2 promotes focal segmental glomerulosclerosis and progressive renal failure (2020) (2)
- Abstract 1954: Functional analyses ofCLDN18-ARHGAP26fusion gene in gastric cancers (2018) (1)
- Serial circulating tumour DNA analysis for locally advanced rectal cancer treated with preoperative therapy: prediction of pathological response and postoperative recurrence (2020) (1)
- Transcriptomic intratumor heterogeneity of breast cancer patient-derived organoids may reflect the unique biological features of the tumor of origin (2023) (1)
- Title Defect in Synaptic Vesicle Precursor Transport and Neuronal Cell Death in KIF 1 A Motor Protein-deficient Mice (1)
- 1006 Mouse Zic1 has an essential tole in cerebellar development (1997) (1)
- Evaluation of the RAS signaling network in response to MEK inhibition using organoids derived from a familial adenomatous polyposis patient (2020) (1)
- Mouse musashi-1, a RNA-binding protein enriched in mammalian neural precursor cells (1998) (1)
- Integration of human inspection and artificial intelligence‐based morphological typing of patient‐derived organoids reveals interpatient heterogeneity of colorectal cancer (2022) (1)
- PDK1/FoxO1 pathway in POMC neurons regulates Pomc expression and 1 food intake 2 (2010) (1)
- Mismatch-specific Thymine DNA Glycosylase (TDG) is Indispensable for Embryonic Development (2002) (1)
- DNA gyrase gyr A gene mutations in ofloxacin-resistant Staphylococcus aureus. (1995) (1)
- Genomic features of Helicobacter pylori‐naïve diffuse‐type gastric cancer (2022) (1)
- Deletion of skeletal muscle Akt1/2 causes osteosarcopenia and reduces lifespan in mice (2022) (1)
- The tumor suppressor Adenomatous Polyposis Coli regulates adult neurogenesis (2009) (1)
- Targeted mutagenesis of BRN-2 gene, one of nervous system specific POU transcription factors (1994) (0)
- Abstract 70: Targeted sequencing analyses of uterine and ovarian carcinosarcoma (2015) (0)
- Abstract 2712: Relationship between CLDN18-ARHGAP fusion gene and clinicopathological features of gastric cancer in young adult (2017) (0)
- In mammals functional transposon (2003) (0)
- Transcriptomic Analyses of Pretreatment Tumor Biopsy Samples, Response to Neoadjuvant Chemoradiotherapy, and Survival in Patients With Advanced Rectal Cancer (2023) (0)
- TUFT1 interacts with RABGAP1 and regulates mTORC1 signaling (2018) (0)
- Establishment of N–ethyl–N–Nitrosourea–Induced Dominantly Inherited Eye Mutations in Mice as Models for Human Eye Diseases (2005) (0)
- Activated β-catenin in Foxp3+ regulatory T cells links inflammatory environments to autoimmunity (2018) (0)
- Kobe University Repository : Kernel タイトル Tit le Pancreat ic β Cell Mass Preserved in Heterozygous PDK 1 Knockout Mice 著者 (2008) (0)
- Abstract 4204: The cellular hierarchy of intestinal tumors (2015) (0)
- Abstract 1543: Systematic functional assessment of driver mutations for individual ovarian cancers (2014) (0)
- Biphasic Response of Pancreatic (cid:2) -Cell Mass to Ablation of Tuberous Sclerosis Complex 2 in Mice (cid:1) (2008) (0)
- Become Susceptible to Polyarthritis Human Parvovirus B19 Transgenic Mice (2004) (0)
- 10:30: Intracochlear Injection of Adenovirus Vector to GJB2 KO Mice (2007) (0)
- Author Correction: Activated β-catenin in Foxp3+ regulatory T cells links inflammatory environments to autoimmunity (2019) (0)
- PAR3 restricts the expansion of neural precursor cells by regulating hedgehog signaling. (2022) (0)
- Correction: Chromatin profile-based identification of a novel ER-positive breast cancer subgroup with reduced ER-responsive element accessibility (2023) (0)
- Supplementary Information rev (2015) (0)
- Reading Evolutionary History of Aminoacyl-tRNA Synthetases from Genome Sequences (1997) (0)
- The tumor suppressor APC is essential for the maintenance of Bergmann glial scaffolds (2009) (0)
- Author Correction: Activation of endothelial β-catenin signaling induces heart failure (2018) (0)
- Analysis of Macrophage Lineage Cells in Mice Lacking Macrophage Scavenger Receptors (1996) (0)
- Mutations in Transgenic Mice (1989) (0)
- Erratum: Administration of BMP2/7 in utero partially reverses Rubinstein-Taybi syndrome-like skeletal defects induced by Pdk1 or Cbp mutations in mice (Journal of Clinical Investigation (2012) 122, 1 (91-106) DOI: 10.1172/JCI59466) (2012) (0)
- Recessive and dominant mutations in transgenic mice. (1990) (0)
- Visualization of functional neural pathways using WGA transgene-3: Adenoviral vector system (1998) (0)
- Achlorhydria by ezrin knockdown: defects in the formation/expansion of apical canaliculi in gastric parietal cells (2005) (0)
- Loss of hypothalamic neurosecretory neurons by targeted mutagenesis of Brn-2, a brain-specific trascription factor (1995) (0)
- [Modification of gene targeting method for functional analysis of the target gene in vivo]. (1997) (0)
- Abstract 3184: Genomic analyses reveal two distinct biologic entities of endometrial endometrioid carcinoma (2016) (0)
- Conditional Mutations of ß-Catenin and APC Reveal Roles for Canonical Wnt Signaling in Lens Development (2007) (0)
- [Neocortical development]. (2004) (0)
- Ethical concerns on sharing genomic data including patients’ family members (2018) (0)
- Prion protein is necessary for a long-term survival of Purkinje cells (1996) (0)
- A method and kit for the assessment of side effects by paclitaxel therapy (2004) (0)
- Corrigendum: Perinatal Gjb2 gene transfer rescues hearing in a mouse model of hereditary deafness. (2019) (0)
- Different functional modes of Brn factors in the stepwise generation of neocortical neuron subtypes and glial cells. (2016) (0)
- Abstract 145: Comprehensive sequencing analyses of uterine and ovarian carcinosarcoma (2016) (0)
- Erratum: Separation of killing and tumorigenic effects of an alkylating agent in mice defective in two of the DNA repair genes (Proceedings of the National Academy of Sciences of the United States of America (April 28, 1998) 95 (5116-5120)) (1998) (0)
- JCA–AACR Joint Symposia in the 73rd Annual Meeting of the Japanese Cancer Association, Yokohama, 25–26 September 2014 (2015) (0)
- For Peer Review ASC-associated inflammation promotes cecal tumorigenesis in aryl hydrocarbon receptor-deficient mice (2013) (0)
- [Anticancer effects of OK-432 (2). Anticancer actions of M phi activated by OK-432]. (1983) (0)
- Objective Evaluation Measures of Genetic Marker Selection in Large-Scale SNP genotyping (2008) (0)
- Genetical analysis of modifier genes which influence the number of intestinal tumors in FAP model mice (1998) (0)
- Identification of single nucleotide polymorphisms (SNPs) associated with adverse effects of gefinitib. (2004) (0)
- An ENU-induced mouse mutant with ADHD-related behavioral abnormality carries a missense mutation in the intracellular C0 domain of NR1 (2007) (0)
- Its Mechanism in Humans and Mice Anti-Inflammatory Activity of PYNOD and (2010) (0)
- A large-scale mouse ENU mutagenesis for developing models of human common diseases (2006) (0)
- Short Communication a-Catenin-Deficient F9 Cells Differentiate into Signet Ring Cells (1999) (0)
- The function of PAR3 in the regulation of hedgehog signaling in primary cilia in neuroepithelial cells (2017) (0)
- Author Correction: Activated β-catenin in Foxp3+ regulatory T cells links inflammatory environments to autoimmunity (2019) (0)
- ABBREVIATIONS MODY : maturation onset diabetes mellitus of the young MODY 2 : maturation onset diabetes mellitus of the young (2004) (0)
- Abstract 2996: Systematic functional identification of driver mutations for individual ovarian cancers. (2013) (0)
- Targeted disruption of the POU-domain transcription factor Brn-2 leads to specific defects in the hypothalamus and postnatal lethality in mice (1996) (0)
- 609 Inactivation of the microtubule-associated protein tau in the mouse (1993) (0)
- Mlh1 Deficient Mice Show High Levels of Mutation at Early Stages of Developmental Process (2004) (0)
- Production and Analysis of Mice Deficient in Microtubule-Associated-Protein Tau. (1995) (0)
- [Antitumor effect of OK-432 (1)--antitumor effect of OK-432 induced interferon-gamma (IFN gamma)]. (1982) (0)
- Pancreatic β Cell Mass Preserved in Heterozygous PDK1 Knockout Mice (2018) (0)
- Analysis of Human Carcinogenesis by Conditional Gene Targeting in Mice (1998) (0)
- PTGER2-β-Catenin Axis Links High Salt Environments to Autoimmunity by Balancing IFNγ and IL-10 in FoxP3+ Regulatory T cells (2018) (0)
- Role of Transcription Factors in the Development of the Hypothalamic Neuroendocrine System (2001) (0)
- Influence of ITPA-deficiency on mammalian cells and mouse central nerve system (2016) (0)
- GRHL2 motif is associated with intratumor heterogeneity of cis-regulatory elements in luminal breast cancer (2022) (0)
- Chromatin profile-based identification of a novel ER-positive breast cancer subgroup with reduced ER-responsive element accessibility (2023) (0)
- C-terminal globulardomäne of adiponectin for treatment of atherosclerosis (2003) (0)
- Transgenic for IL-10 Resembling Sjögren's Syndrome in Mice Fas Ligand-Mediated Exocrinopathy (1999) (0)
- Targeted mutagenesis of MGL-1 gene, mouse homologue of the Drosophila tumor suppressor gene L (2) GL (1994) (0)
- ROLE OF ASC IN HELICOBACTER PYLORI INFECTION (2008) (0)
- Pancreatic beta cell mass preserved in heterozygous PDK1 knockout mice. (2008) (0)
- Tokuda Akihiro Tomida Shinya Toyokuni Hitoshi Tsuda Shoichiro Tsugane Tatsuhiko Tsunoda Heiichiro Udono Koji Ueda Yoshimasa Uehara Hiroo Ueno Kazuo Umezawa Toshikazu Ushijima Toshihiko Wakabayashi Kenji Wakai Tetsuro Watabe (2016) (0)
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What Schools Are Affiliated With Tetsuo Noda?
Tetsuo Noda is affiliated with the following schools:
