Theofilus Johannes Visser
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Philosophy
Theofilus Johannes Visser's Degrees
- Bachelors Biology Erasmus University Rotterdam
- Masters Biomedical Sciences Erasmus University Rotterdam
- PhD Endocrinology Erasmus University Rotterdam
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(Suggest an Edit or Addition)Theofilus Johannes Visser's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Subclinical Hypothyroidism Is an Independent Risk Factor for Atherosclerosis and Myocardial Infarction in Elderly Women: The Rotterdam Study (2000) (1358)
- Somatostatin receptor scintigraphy with [111In-DTPA-d-Phe1]- and [123I-Tyr3]-octreotide: the Rotterdam experience with more than 1000 patients (1993) (1120)
- Identification of Monocarboxylate Transporter 8 as a Specific Thyroid Hormone Transporter* (2003) (630)
- Interactions of Persistent Environmental Organohalogens With the Thyroid Hormone System: Mechanisms and Possible Consequences for Animal and Human Health (1998) (622)
- Association between mutations in a thyroid hormone transporter and severe X-linked psychomotor retardation (2004) (595)
- Somatostatin receptor scintigraphy with indium-111-DTPA-D-Phe-1-octreotide in man: metabolism, dosimetry and comparison with iodine-123-Tyr-3-octreotide. (1992) (420)
- Plasma membrane transport of thyroid hormones and its role in thyroid hormone metabolism and bioavailability. (2001) (387)
- Reduced activation and increased inactivation of thyroid hormone in tissues of critically ill patients. (2003) (384)
- Minireview: thyroid hormone transporters: the knowns and the unknowns. (2010) (375)
- Potent inhibition of estrogen sulfotransferase by hydroxylated PCB metabolites: a novel pathway explaining the estrogenic activity of PCBs. (2000) (366)
- Association of maternal thyroid function during early pregnancy with offspring IQ and brain morphology in childhood: a population-based prospective cohort study. (2016) (333)
- Abnormal thyroid hormone metabolism in mice lacking the monocarboxylate transporter 8. (2007) (315)
- Iodothyronine levels in the human developing brain: major regulatory roles of iodothyronine deiodinases in different areas. (2004) (313)
- Radiotherapy with a Radiolabeled Somatostatin Analogue, [111In‐DTPA‐d‐Phe1]‐Octreotide (1994) (274)
- Effective cellular uptake and efflux of thyroid hormone by human monocarboxylate transporter 10. (2008) (270)
- Thyroid hormone concentrations, disease, physical function, and mortality in elderly men. (2005) (269)
- Chemically defined neuron groups and their subpopulations in the glomerular layer of the rat main olfactory bulb (1995) (252)
- The monocarboxylate transporter 8 linked to human psychomotor retardation is highly expressed in thyroid hormone-sensitive neuron populations. (2005) (250)
- Polymorphisms in thyroid hormone pathway genes are associated with plasma TSH and iodothyronine levels in healthy subjects. (2003) (248)
- Hypothalamic thyroid hormone catabolism acts as a gatekeeper for the seasonal control of body weight and reproduction. (2007) (246)
- Hypoxia-inducible factor induces local thyroid hormone inactivation during hypoxic-ischemic disease in rats. (2008) (242)
- Serum 3,3',5'-triiodothyronine (rT3) and 3,5,3'-triiodothyronine/rT3 are prognostic markers in critically ill patients and are associated with postmortem tissue deiodinase activities. (2005) (233)
- Kinetic evidence suggesting two mechanisms for iodothyronine 5'-deiodination in rat cerebral cortex. (1982) (232)
- Biotransformation of brominated flame retardants into potentially endocrine-disrupting metabolites, with special attention to 2,2',4,4'-tetrabromodiphenyl ether (BDE-47). (2008) (227)
- Thyroid disease in pregnancy: new insights in diagnosis and clinical management (2017) (226)
- Identification of DIO2 as a new susceptibility locus for symptomatic osteoarthritis. (2008) (220)
- Somatostatin receptor-mediated imaging and therapy: basic science, current knowledge, limitations and future perspectives (2001) (219)
- Thyroid hormone transport in and out of cells (2008) (219)
- Sulfation of thyroid hormone and dopamine during human development: ontogeny of phenol sulfotransferases and arylsulfatase in liver, lung, and brain. (2001) (216)
- Comparison of (111)In-labeled somatostatin analogues for tumor scintigraphy and radionuclide therapy. (1998) (215)
- Transporters MCT8 and OATP1C1 maintain murine brain thyroid hormone homeostasis. (2014) (209)
- Pathways of thyroid hormone metabolism. (1996) (209)
- Optimising conditions for radiolabelling of DOTA-peptides with 90Y, 111In and 177Lu at high specific activities (2003) (206)
- A 28-day oral dose toxicity study enhanced to detect endocrine effects of hexabromocyclododecane in Wistar rats. (2006) (201)
- Evidence for two pathways of iodothyronine 5'-deiodination in rat pituitary that differ in kinetics, propylthiouracil sensitivity, and response to hypothyroidism. (1983) (199)
- Hypothyroxinemia and TPO-antibody positivity are risk factors for premature delivery: the generation R study. (2013) (199)
- Cerebral cortex responds rapidly to thyroid hormones. (1981) (199)
- A Meta-Analysis of Thyroid-Related Traits Reveals Novel Loci and Gender-Specific Differences in the Regulation of Thyroid Function (2013) (193)
- Thyroid hormone transport by the human monocarboxylate transporter 8 and its rate-limiting role in intracellular metabolism. (2006) (191)
- Mutations in the iodotyrosine deiodinase gene and hypothyroidism. (2008) (191)
- Interference of polychlorinated biphenyls in hepatic and brain thyroid hormone metabolism in fetal and neonatal rats. (1993) (190)
- Thyroid Hormone Transporters (2007) (189)
- Clinical phenotype and mutant TRα1. (2012) (188)
- Maternal thyroid function during early pregnancy and cognitive functioning in early childhood: the generation R study. (2011) (187)
- Ontogeny of type I and type III deiodinase activities in embryonic and posthatch chicks: relationship with changes in plasma triiodothyronine and growth hormone levels. (1992) (184)
- Receptor scintigraphy with a radioiodinated somatostatin analogue: radiolabeling, purification, biologic activity, and in vivo application in animals. (1990) (183)
- Identification of thyroid hormone transporters. (1999) (182)
- Thyroid hormone transporters in health and disease. (2005) (178)
- Yttrium-90 and indium-111 labelling, receptor binding and biodistribution of [DOTA0,d-Phe1,Tyr3]octreotide, a promising somatostatin analogue for radionuclide therapy (1997) (173)
- Potent inhibition of estrogen sulfotransferase by hydroxylated metabolites of polyhalogenated aromatic hydrocarbons reveals alternative mechanism for estrogenic activity of endocrine disrupters. (2002) (173)
- Endocrine effects of tetrabromobisphenol-A (TBBPA) in Wistar rats as tested in a one-generation reproduction study and a subacute toxicity study. (2008) (171)
- Developmental trends in cord and postpartum serum thyroid hormones in preterm infants. (2004) (167)
- Identification of Novel Genetic Loci Associated with Thyroid Peroxidase Antibodies and Clinical Thyroid Disease (2014) (163)
- Maternal thyroid hormone parameters during early pregnancy and birth weight: the Generation R Study. (2013) (160)
- Thyroid function in pregnancy: what is normal? (2015) (159)
- In vitro inhibition of thyroid hormone sulfation by hydroxylated metabolites of halogenated aromatic hydrocarbons. (1998) (158)
- Subcellular localization of a rat liver enzyme converting thyroxine into tri-iodothyronine and possible involvement of essential thiol groups. (1976) (152)
- High-normal thyroid function and risk of atrial fibrillation: the Rotterdam study. (2008) (152)
- Minireview: Pathophysiological importance of thyroid hormone transporters. (2009) (151)
- Ontogeny of iodothyronine deiodinases in human liver. (1998) (151)
- Thyroid Hormone Transport by the Heterodimeric Human System L Amino Acid Transporter. (2001) (149)
- Type II and type III deiodinase activity in human placenta as a function of gestational age. (1996) (148)
- D-lysine reduction of indium-111 octreotide and yttrium-90 octreotide renal uptake. (1997) (147)
- Role of sulfation in thyroid hormone metabolism. (1994) (147)
- Glucuronidation of thyroid hormone in rat liver: effects of in vivo treatment with microsomal enzyme inducers and in vitro assay conditions. (1993) (146)
- Induction of thyroid hormone-degrading deiodinase in cardiac hypertrophy and failure. (2002) (145)
- Biochemical mechanisms of thyroid hormone deiodination. (2005) (144)
- Mechanism-based testing strategy using in vitro approaches for identification of thyroid hormone disrupting chemicals. (2013) (142)
- Synthesis and some properties of sulfate esters and sulfamates of iodothyronines. (1985) (139)
- Neuroanatomical pathways for thyroid hormone feedback in the human hypothalamus. (2005) (136)
- Localisation and mechanism of renal retention of radiolabelled somatostatin analogues (2005) (135)
- Maternal thyroid autoimmunity during pregnancy and the risk of attention deficit/hyperactivity problems in children: the Generation R Study. (2012) (135)
- Maternal early pregnancy and newborn thyroid hormone parameters: the Generation R study. (2012) (134)
- A common variation in deiodinase 1 gene DIO1 is associated with the relative levels of free thyroxine and triiodothyronine. (2008) (134)
- Endocrine effects of hexabromocyclododecane (HBCD) in a one-generation reproduction study in Wistar rats. (2009) (131)
- Thyroxine and 3,3',5-triiodothyronine are glucuronidated in rat liver by different uridine diphosphate-glucuronyltransferases. (1991) (131)
- Tissue thyroid hormone levels in critical illness. (2005) (130)
- Multiple neurotransmitters in the tuberomammillary nucleus: Comparison of rat, mouse, and guinea pig (1992) (130)
- Inhibition of renal uptake of indium-111-DTPA-octreotide in vivo. (1996) (129)
- Human fetal and cord serum thyroid hormones: developmental trends and interrelationships. (2004) (128)
- Effects of serum TSH and FT4 levels and the TSHR‐Asp727Glu polymorphism on bone: the Rotterdam Study (2007) (123)
- Molecular aspects of thyroid hormone transporters, including MCT8, MCT10, and OATPs, and the effects of genetic variation in these transporters. (2010) (123)
- Characteristics of active transport of thyroid hormone into rat hepatocytes. (1981) (123)
- Megalin is essential for renal proximal tubule reabsorption of (111)In-DTPA-octreotide. (2005) (121)
- Effects of evening vs morning levothyroxine intake: a randomized double-blind crossover trial. (2010) (119)
- Internalization of radiolabelled [DTPA0]octreotide and [DOTA0,Tyr3]octreotide: peptides for somatostatin receptor-targeted scintigraphy and radionuclide therapy. (1998) (119)
- RAISED TOTAL THYROXINE AND FREE THYROXINE INDEX BUT NORMAL FREE THYROXINE A Serum Abnormality due to Inherited Increased Affinity of Iodothyronines for Serum Binding Protein (1979) (118)
- Impact of Oatp1c1 deficiency on thyroid hormone metabolism and action in the mouse brain. (2012) (117)
- Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation (2018) (117)
- Deiodination of thyroid hormone by human liver. (1988) (116)
- Neuropeptide Y Innervation and Neuropeptide-Y-Y1-Receptor-Expressing Neurons in the Paraventricular Hypothalamic Nucleus of the Mouse (1999) (116)
- Regulation of thyroid hormone metabolism during fetal development (1999) (116)
- Inhibition of thyroxine transport into cultured rat hepatocytes by serum of nonuremic critically ill patients: effects of bilirubin and nonesterified fatty acids. (1993) (116)
- Genetic variation in thyroid hormone pathway genes; polymorphisms in the TSH receptor and the iodothyronine deiodinases. (2006) (114)
- Conversion of thyroxine into tri-iodothyronine by rat liver homogenate. (1975) (113)
- The role of sulfation in thyroid hormone metabolism (1990) (113)
- Induction of type 3 deiodinase activity in inflammatory cells of mice with chronic local inflammation. (2005) (113)
- A Phytoestrogen-Rich Diet Increases Energy Expenditure and Decreases Adiposity in Mice (2007) (112)
- Thyroid hormones, dementia, and atrophy of the medial temporal lobe. (2006) (111)
- Maternal Thyroid Function During Pregnancy and Behavioral Problems in the Offspring: The Generation R Study (2011) (111)
- Acute posttranscriptional regulation of cerebrocortical and pituitary iodothyronine 5'-deiodinases by thyroid hormone. (1984) (110)
- The association of polymorphisms in the type 1 and 2 deiodinase genes with circulating thyroid hormone parameters and atrophy of the medial temporal lobe. (2007) (109)
- Active transport of triiodothyronine (T3) into isolated rat liver cells (1978) (109)
- Pre‐clinical comparison of [DTPA0] octreotide, [DTPA0,Tyr3] octreotide and [DOTA0,Tyr3] octreotide as carriers for somatostatin receptor‐targeted scintigraphy and radionuclide therapy (1998) (109)
- Genetics and phenomics of thyroid hormone transport by MCT8 (2010) (108)
- In vivo use of a radioiodinated somatostatin analogue: dynamics, metabolism, and binding to somatostatin receptor-positive tumors in man. (1991) (108)
- An ultrastructural study of 5-hydroxytryptamine-, thyrotropin-releasing hormone- and substance P-immunoreactive axonal boutons in the motor nucleus of spinal cord segments L7-S1 in the adult cat (1987) (106)
- Tumor response after [(90)Y-DOTA(0),Tyr(3)]octreotide radionuclide therapy in a transplantable rat tumor model is dependent on tumor size. (2001) (105)
- Mechanisms of Disease: psychomotor retardation and high T3 levels caused by mutations in monocarboxylate transporter 8 (2006) (105)
- Early expression of thyroid hormone deiodinases and receptors in human fetal cerebral cortex. (2002) (104)
- Effect of starvation and subsequent refeeding on thyroid function and release of hypothalamic thyrotropin-releasing hormone. (1992) (104)
- Decreased transport of thyroxine (T4), 3,3′‐5‐triiodothyronine (T3) and 3,3′,5′‐triiodothyronine (rT3) into rat hepatocytes in primary culture due to a decrease of cellular ATP content and various drugs (1982) (103)
- Serum thyroid hormones in preterm infants: associations with postnatal illnesses and drug usage. (2005) (102)
- The hypothalamic-pituitary-thyroid axis in preterm infants; changes in the first 24 hours of postnatal life. (2004) (101)
- Clinical phenotype of a new type of thyroid hormone resistance caused by a mutation of the TRα1 receptor: consequences of LT4 treatment. (2013) (100)
- Regulation of iodothyronine deiodinases in the Pax8-/- mouse model of congenital hypothyroidism. (2003) (100)
- A new polymorphism in the type II deiodinase gene is associated with circulating thyroid hormone parameters. (2005) (100)
- Polymorphisms in the brain‐specific thyroid hormone transporter OATP1C1 are associated with fatigue and depression in hypothyroid patients (2008) (100)
- Sorafenib-induced hypothyroidism is associated with increased type 3 deiodination. (2010) (99)
- Ethnic differences in maternal thyroid parameters during pregnancy: the Generation R study. (2013) (98)
- Polymorphisms in type 2 deiodinase are not associated with well-being, neurocognitive functioning, and preference for combined thyroxine/3,5,3'-triiodothyronine therapy. (2005) (97)
- Identification of molecular mechanisms related to nonthyroidal illness syndrome in skeletal muscle and adipose tissue from patients with septic shock (2008) (97)
- Beneficial effects of propylthiouracil plus L-thyroxine treatment in a patient with a mutation in MCT8. (2008) (96)
- Thyroid Autoimmunity Impairs the Thyroidal Response to Human Chorionic Gonadotropin: Two Population-Based Prospective Cohort Studies (2016) (95)
- Left-ventricular remodeling after myocardial infarction is associated with a cardiomyocyte-specific hypothyroid condition. (2011) (95)
- Uptake of thyroid hormones in neonatal rat cardiac myocytes. (1996) (95)
- Sunitinib-induced hypothyroidism is due to induction of type 3 deiodinase activity and thyroidal capillary regression. (2011) (94)
- Sulfation preceding deiodination of iodothyronines in rat hepatocytes. (1983) (94)
- Evidence for the involvement of hypothalamic dopamine and thyrotrophin-releasing hormone in suckling-induced release of prolactin. (1981) (94)
- Inhibition of thyroid hormone sulfation by hydroxylated metabolites of polychlorinated biphenyls. (1998) (94)
- Reference ranges and determinants of total hCG levels during pregnancy: the Generation R Study (2015) (92)
- Tumour uptake of the radiolabelled somatostatin analogue [DOTA0,TYR3]octreotide is dependent on the peptide amount (1999) (91)
- The type II iodothyronine deiodinase is up-regulated in skeletal muscle during prolonged critical illness. (2007) (91)
- Radioimmunoassay of reverse tri-iodothyronine. (1977) (90)
- Placental iodothyronine deiodinase expression in normal and growth-restricted human pregnancies. (2003) (90)
- Impact of monocarboxylate transporter-8 deficiency on the hypothalamus-pituitary-thyroid axis in mice. (2010) (90)
- Preclinical comparison of (111)In-labeled DTPA- or DOTA-bombesin analogs for receptor-targeted scintigraphy and radionuclide therapy. (2002) (90)
- Deiodinase activity is present in Xenopus laevis during early embryogenesis. (2006) (88)
- Iodothyronine deiodinase enzyme activities in bone (2008) (88)
- Hypothyroidism induces type I iodothyronine deiodinase expression in tilapia liver. (2001) (88)
- Effect of dose and specific activity on tissue distribution of indium-111-pentetreotide in rats. (1995) (87)
- Sequential deiodination of thyroxine in rat liver homogenate. (1978) (87)
- New phenotypes in thyroid dyshormonogenesis: hypothyroidism due to DUOX2 mutations. (2007) (87)
- Genotype-phenotype relationship in patients with mutations in thyroid hormone transporter MCT8. (2008) (87)
- Low urinary iodine excretion during early pregnancy is associated with alterations in executive functioning in children. (2012) (86)
- A 28-day oral dose toxicity study enhanced to detect endocrine effects of a purified technical pentabromodiphenyl ether (pentaBDE) mixture in Wistar rats. (2008) (86)
- Hypothyroidism in rats decreases peripheral glucose utilisation, a defect partially corrected by central leptin infusion (2005) (85)
- Evaluation of radiolabelled bombesin analogues for receptor‐targeted scintigraphy and radiotherapy (1999) (85)
- Plasma thyroxine, 3,3',5-triiodothyronine and 3,3',5'-triiodothyronine during beta-adrenergic blockade in hyperthyroidism. (1977) (85)
- Psychological well-being correlates with free thyroxine but not free 3,5,3'-triiodothyronine levels in patients on thyroid hormone replacement. (2006) (85)
- Euthyroid sick syndrome in meningococcal sepsis: the impact of peripheral thyroid hormone metabolism and binding proteins. (2005) (84)
- Characterization of human iodothyronine sulfotransferases. (1999) (84)
- Changes in the central component of the hypothalamus-pituitary-thyroid axis in a rabbit model of prolonged critical illness (2009) (83)
- Thyroid function within the normal range and the risk of depression: a population-based cohort study. (2014) (82)
- Assessment of TRH as a potential MSH release stimulating factor in Xenopus laevis (1987) (81)
- Thyroxine plus low-dose, slow-release triiodothyronine replacement in hypothyroidism: proof of principle. (2004) (81)
- 5‐Hydroxytryptamine, substance P, and thyrotropin‐releasing hormone in the adult cat spinal cord segment L7: Immunohistochemical and chemical studies (1990) (81)
- Expression of thyroid hormone transporters during critical illness. (2009) (81)
- Generation of thyrotropin-releasing hormone receptor 1-deficient mice as an animal model of central hypothyroidism. (2004) (80)
- Rapid and selective inner ring deiodination of thyroxine sulfate by rat liver deiodinase. (1985) (79)
- Tissue-specific alterations in thyroid hormone homeostasis in combined Mct10 and Mct8 deficiency. (2014) (78)
- Thyroid hormone transport by monocarboxylate transporters. (2007) (78)
- Effects of evening vs morning thyroxine ingestion on serum thyroid hormone profiles in hypothyroid patients (2006) (78)
- Activation and inactivation of thyroid hormone by type I iodothyronine deiodinase (1994) (78)
- Substitution of cysteine for selenocysteine in the catalytic center of type III iodothyronine deiodinase reduces catalytic efficiency and alters substrate preference. (2003) (77)
- Different effects of continuous infusion of interleukin-1 and interleukin-6 on the hypothalamic-hypophysial-thyroid axis. (1994) (77)
- Monocarboxylate transporter 8 expression in the human placenta: the effects of severe intrauterine growth restriction. (2006) (77)
- Maternal early-pregnancy thyroid function is associated with subsequent hypertensive disorders of pregnancy: the generation R study. (2014) (76)
- Sulfation of thyroid hormone by estrogen sulfotransferase. (1999) (76)
- Tetrac can replace thyroid hormone during brain development in mouse mutants deficient in the thyroid hormone transporter mct8. (2013) (76)
- Serum thyroid hormones in preterm infants and relationships to indices of severity of intercurrent illness. (2005) (75)
- Kinetics of enzymic reductive deiodination of iodothyronines. Effect of pH. (1979) (75)
- Differential expression of sulfotransferase enzymes involved in thyroid hormone metabolism during human placental development. (2001) (75)
- Functional analysis of monocarboxylate transporter 8 mutations identified in patients with X-linked psychomotor retardation and elevated serum triiodothyronine. (2007) (75)
- Increased glucuronidation of thyroid hormone in hexachlorobenzene-treated rats. (1993) (75)
- Extrathyroidal effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on thyroid hormone turnover in male Sprague-Dawley rats. (1997) (75)
- Characteristics of iodothyronine tyrosyl ring deiodination by rat cerebral cortical microsomes. (1983) (74)
- Metabolism of Thyroid Hormone (2012) (74)
- Thyroid hormone transporters. (2010) (74)
- INHERITED THYROXINE EXCESS: A SERUM ABNORMALITY DUE TO AN INCREASED AFFINITY FOR MODIFIED ALBUMIN (1981) (74)
- Thyroid hormone transport and metabolism by organic anion transporter 1C1 and consequences of genetic variation. (2008) (73)
- Decreased cellular uptake and metabolism in Allan-Herndon-Dudley syndrome (AHDS) due to a novel mutation in the MCT8 thyroid hormone transporter (2005) (73)
- Expression of Chicken Hepatic Type I and Type III Iodothyronine Deiodinases during Embryonic Development. (1997) (73)
- Novel pathogenic mechanism suggested by ex vivo analysis of MCT8 (SLC16A2) mutations (2009) (71)
- Characterization of the uridine diphosphate-glucuronosyltransferase-catalyzing thyroid hormone glucuronidation in man. (2000) (71)
- Expression of thyroid hormone transporters in the human hypothalamus. (2011) (71)
- Genetic determination of the hypothalamic-pituitary-thyroid axis: where do we stand? (2015) (70)
- Serum thyroid hormone levels in healthy children from birth to adulthood and in short children born small for gestational age. (2012) (70)
- Physiological thyroid hormone levels regulate numerous skeletal muscle transcripts. (2009) (70)
- Pre‐clinical evaluation of [111In‐DTPA‐Pro1, Tyr4]bombesin, a new radioligand for bombesin‐receptor scintigraphy (1999) (69)
- Serum Thyroid Function, Mortality and Disability in Advanced Old Age: The Newcastle 85+ Study (2016) (69)
- Characterization of thyroid hormone sulfotransferases. (1998) (68)
- In vitro and mouse studies supporting therapeutic utility of triiodothyroacetic acid in MCT8 deficiency. (2014) (68)
- Developmental control of iodothyronine deiodinases by cortisol in the ovine fetus and placenta near term. (2006) (68)
- A large-scale association analysis of 68 thyroid hormone pathway genes with serum TSH and FT4 levels. (2011) (67)
- Effect of thyroid status and paraventricular area lesions on the release of thyrotropin-releasing hormone and catecholamines into hypophysial portal blood. (1988) (67)
- SERUM CONCENTRATIONS OF METABOLITES OF VITAMIN D IN PATIENTS WITH CHRONIC RENAL FAILURE (CRF). CONSEQUENCES FOR THE TREATMENT WITH 1‐α‐HYDROXY‐DERIVATIVES (1981) (67)
- Regulation of type III iodothyronine deiodinase expression in human cell lines. (2006) (66)
- Dronerarone acts as a selective inhibitor of 3,5,3'-triiodothyronine binding to thyroid hormone receptor-alpha1: in vitro and in vivo evidence. (2003) (66)
- Distribution of thyrotropin‐releasing hormone (TRH)‐containing cells and fibers in the human hypothalamus (1994) (66)
- The pathophysiological consequences of thyroid hormone transporter deficiencies: Insights from mouse models. (2013) (65)
- Knockdown of type 3 iodothyronine deiodinase severely perturbs both embryonic and early larval development in zebrafish. (2014) (65)
- Carrier-mediated transport of thyroid hormone into rat hepatocytes is rate-limiting in total cellular uptake and metabolism. (1986) (65)
- Identification and functional characterization of zebrafish solute carrier Slc16a2 (Mct8) as a thyroid hormone membrane transporter. (2011) (64)
- Large induction of type III deiodinase expression after partial hepatectomy in the regenerating mouse and rat liver. (2009) (64)
- A polymorphism in type I deiodinase is associated with circulating free insulin-like growth factor I levels and body composition in humans. (2005) (64)
- Iodine deficiency associated with parenteral nutrition in extreme preterm infants (2003) (64)
- The addition of DTPA to [177Lu-DOTA0,Tyr3]octreotate prior to administration reduces rat skeleton uptake of radioactivity (2003) (64)
- Consequences of monocarboxylate transporter 8 deficiency for renal transport and metabolism of thyroid hormones in mice. (2010) (64)
- Glucuronidation of thyroid hormone by human bilirubin and phenol UDP‐glucuronyltransferase isoenzymes (1993) (63)
- Central stimulatory effect of leptin on T3 production is mediated by brown adipose tissue type II deiodinase. (2002) (63)
- Multiple UDP‐glucuronyltransferases for the glucuronidation of thyroid hormone with preference for 3,3',5'‐triiodothyronine (reverse T3) (1993) (62)
- Type 3 deiodinase is highly expressed in infiltrating neutrophilic granulocytes in response to acute bacterial infection. (2008) (61)
- Novel neuroanatomical pathways for thyroid hormone action in the human anterior pituitary. (2006) (61)
- INFLUENCE OF 1α‐(OH)D3 ADMINISTRATION ON BONE AND BONE MINERAL METABOLISM IN PATIENTS ON CHRONIC GLUCOCORTICOID TREATMENT; A DOUBLE BLIND CONTROLLED STUDY (1983) (61)
- Maternal and Birth Characteristics Are Determinants of Offspring Thyroid Function. (2016) (61)
- Acute pretranslational regulation of type III iodothyronine deiodinase by growth hormone and dexamethasone in chicken embryos (1999) (61)
- Changes within the thyroid axis during critical illness. (2006) (61)
- Pilot study on the assessment of the setpoint of the hypothalamus-pituitary-thyroid axis in healthy volunteers. (2010) (61)
- Tissue-Specific Suppression of Thyroid Hormone Signaling in Various Mouse Models of Aging (2016) (60)
- Organic anion transporter 1B1: an important factor in hepatic thyroid hormone and estrogen transport and metabolism. (2008) (60)
- Fat mobilization and plasma hormone levels in fasted dogs. (1981) (59)
- Study of the transport of thyroid hormone by transporters of the SLC10 family (2010) (59)
- Type 2 iodothyronine deiodinase in skeletal muscle: effects of hypothyroidism and fasting. (2009) (58)
- Different thyroid hormone‐deiodinating enzymes in tilapia (Oreochromis niloticus) liver and kidney (1993) (58)
- Maternal and umbilical cord levels of T4, FT4, TSH, TPOAb, and TgAb in term infants and neurodevelopmental outcome at 5.5 years. (2013) (58)
- Characterization of a Propylthiouracil-Insensitive Type I Iodothyronine Deiodinase. (1997) (57)
- Thyroid hormone independent associations between serum TSH levels and indicators of bone turnover in cured patients with differentiated thyroid carcinoma. (2008) (57)
- Different pathways of iodothyronine 5'-deiodination in rat cerebral cortex. (1981) (57)
- In vitro inhibition of thyroid hormone sulfation by polychlorobiphenylols: isozyme specificity and inhibition kinetics. (1998) (56)
- Transient hypothyroxinemia in preterm infants: the role of cord sera thyroid hormone levels adjusted for prenatal and intrapartum factors. (2005) (56)
- Genetics and phenomics of hypothyroidism and goiter due to iodotyrosine deiodinase (DEHAL1) gene mutations (2010) (56)
- Involvement of thyroid hormones in the effect of intracerebroventricular leptin infusion on uncoupling protein-3 expression in rat muscle. (2000) (55)
- Bexarotene-induced hypothyroidism: bexarotene stimulates the peripheral metabolism of thyroid hormones. (2007) (55)
- Resistance to thyroid hormone mediated by defective thyroid hormone receptor alpha. (2013) (55)
- The impact of a TSH receptor gene polymorphism on thyroid‐related phenotypes in a healthy Danish twin population (2007) (54)
- Serum thyroid hormone concentrations during prolonged reduction of dietary intake. (1978) (54)
- Identification, functional analysis, prevalence and treatment of monocarboxylate transporter 8 (MCT8) mutations in a cohort of adult patients with mental retardation (2013) (54)
- THYROTROPHIN BINDING INHIBITING IMMUNOGLOBULINS IN GRAVES' DISEASE BEFORE, DURING AND AFTER ANTITHYROID THERAPY, AND ITS RELATION TO LONG‐ACTING THYROID STIMULATOR (1980) (54)
- Concentrations of Seven Iodothyronine Metabolites in Brain Regions and the Liver of the Adult Rat. (2002) (53)
- Rapid deiodination of triiodothyronine sulfate by rat liver microsomal fraction. (1983) (53)
- Disorder of thyroid hormone transport into the tissues. (2017) (53)
- A 28-day oral dose toxicity study in Wistar rats enhanced to detect endocrine effects of decabromodiphenyl ether (decaBDE). (2008) (52)
- Regulation of thyroid hormone metabolism during fasting and refeeding in chicken. (1999) (52)
- Effects of long-term food reduction on the hypothalamus-pituitary-thyroid axis in male and female rats. (1996) (52)
- Thr92Ala polymorphism in the type 2 deiodinase is not associated with T4 dose in athyroid patients or patients with Hashimoto thyroiditis (2009) (52)
- Developmental and cell-specific expression of thyroid hormone transporters in the mouse cochlea. (2011) (51)
- Dysregulation of iodothyronine deiodinase enzyme expression and function in human pituitary tumours (2002) (51)
- Characterization of Iodothyronine Outer Ring and Inner Ring Deiodinase Activities in the Blue Tilapia, Oreochromis Aureus. (1997) (51)
- Resistance to Thyroid Hormone Alpha in an 18-Month-Old Girl: Clinical, Therapeutic, and Molecular Characteristics. (2016) (51)
- Increased thyroxine sulfate levels in critically ill patients as a result of a decreased hepatic type I deiodinase activity. (2005) (50)
- Metabolism of triiodothyronine in rat hepatocytes. (1989) (50)
- Impairment of the selenoenzyme type I iodothyronine deiodinase in C3H/He mice. (1993) (50)
- Dose Dependency and a Functional Cutoff for TPO-Antibody Positivity During Pregnancy (2018) (50)
- Hydrolysis of iodothyronine conjugates by intestinal bacteria. (1988) (50)
- Thyroid hormone levels in children with Prader–Willi syndrome before and during growth hormone treatment (2007) (49)
- Characterization of iodothyronine sulfatase activities in human and rat liver and placenta. (2002) (49)
- Preliminary evidence that a functional polymorphism in type 1 deiodinase is associated with enhanced potentiation of the antidepressant effect of sertraline by triiodothyronine. (2009) (49)
- Effects of hypothyroidism on hypothalamic release of thyrotropin-releasing hormone in rats. (1992) (49)
- Quality of life in patients with primary hypothyroidism related to BMI. (2015) (49)
- Uptake of triiodothyroacetic acid and its effect on thyrotropin secretion in cultured anterior pituitary cells. (1994) (48)
- Thyroid hormone transporters. (2005) (48)
- Inhibition of iodothyronine 5′‐deiodinase by thioureylenes; Structure‐activity relationship (1979) (48)
- 99mTc-MIBI, 99mTc-tetrofosmin and 99mTc-Q12 in vitro and in vivo. (1998) (48)
- A comparative study of the immunohistochemical localization of a presumptive proctolin-like peptide, thyrotropin-releasing hormone and 5-hydroxytryptamine in the rat central nervous system (1987) (48)
- Evidence that the self-induced metabolism of 1,25-dihydroxyvitamin D-3 limits the homologous up-regulation of its receptor in rat osteosarcoma cells. (1988) (47)
- A tentative review of recent in vitro observations of the enzymatic deiodination of iodothyronines and its possible physiological implications (1978) (46)
- Transport of Iodothyronines by Human L-Type Amino Acid Transporters. (2015) (46)
- Diverse Genotypes and Phenotypes of Three Novel Thyroid Hormone Receptor-α Mutations. (2016) (46)
- Control of prolactin release induced by suckling. (1987) (45)
- Hypothalamo-hypophysial-thyroid axis in streptozotocin-induced diabetes. (1992) (45)
- Location of rat liver iodothyronine deiodinating enzymes in the endoplasmic reticulum. (1979) (45)
- Transient hypothyroxinaemia in preterm infants. (2006) (44)
- Inactivation and affinity-labeling of rat liver iodothyronine deiodinase with N-bromoacetyl-3,3',5-triiodothyronine. (1984) (44)
- Species differences in liver type I iodothyronine deiodinase. (1992) (44)
- Mild maternal thyroid dysfunction at delivery of infants born ≤34 weeks and neurodevelopmental outcome at 5.5 years. (2012) (44)
- Different regulation of thyroid hormone transport in liver and pituitary: its possible role in the maintenance of low T3 production during nonthyroidal illness and fasting in man. (1996) (44)
- The type 2 deiodinase Thr92Ala polymorphism is associated with increased bone turnover and decreased femoral neck bone mineral density (2010) (44)
- Endogenous growth hormone controls high plasma levels of 3,3',5-triiodothyronine (T3) in growing chickens by decreasing the T3-degrading type III deiodinase activity. (1993) (44)
- Effectiveness and safety of the tri-iodothyronine analogue Triac in children and adults with MCT8 deficiency: an international, single-arm, open-label, phase 2 trial. (2019) (43)
- Heterologous up-regulation of the 1,25-dihydroxyvitamin D3 receptor by parathyroid hormone (PTH) and PTH-like peptide in osteoblast-like cells. (1988) (43)
- In vitro and in vivo studies of substance P receptor expression in rats with the new analog [indium-111-DTPA-Arg1]substance P. (1996) (43)
- Interference of a mutant thyroid hormone receptor alpha1 with hepatic glucose metabolism. (2009) (42)
- Resistance to Thyroid Hormone due to Heterozygous Mutations in Thyroid Hormone Receptor Alpha. (2017) (42)
- Mutated Thyroid Hormone Transporter OATP1C1 Associates with Severe Brain Hypometabolism and Juvenile Neurodegeneration. (2018) (42)
- Thyroid hormone availability in the human fetal brain: novel entry pathways and role of radial glia (2019) (42)
- Characterization of the Subunit Structure of the Catalytically Active Type I Iodothyronine Deiodinase* (2001) (42)
- Effects of pentachlorophenol and hydroxylated polychlorinated biphenyls on thyroid hormone conjugation in a rat and a human hepatoma cell line. (1999) (42)
- The Asp727Glu polymorphism in the TSH receptor is associated with insulin resistance in healthy elderly men (2007) (42)
- Serum triiodothyronine sulfate in man measured by radioimmunoassay. (1989) (42)
- Development of a radioimmunoassay for triiodothyronine sulfate. (1988) (41)
- Selenium Status Is Positively Associated with Bone Mineral Density in Healthy Aging European Men (2016) (41)
- Visualization of the thymus by substance P receptor scintigraphy in man (1996) (41)
- Effects of propylthiouracil on the biliary clearance of thyroxine (T4) in rats: decreased excretion of 3,5,3'-triiodothyronine glucuronide and increased excretion of 3,3',5'-triiodothyronine glucuronide and T4 sulfate. (1989) (41)
- Modification of rat liver iodothyronine 5'-deiodinase activity with diethylpyrocarbonate and rose bengal; evidence for an active site histidine residue. (1984) (41)
- SHORT‐TERM EFFECT OF PREDNISONE ON SERUM 1,25‐DIHYDROXYVITAMIN D IN NORMAL INDIVIDUALS AND IN HYPER‐AND HYPOPARATHYROIDISM (1982) (41)
- Characterization of recombinant Xenopus laevis type I iodothyronine deiodinase: substitution of a proline residue in the catalytic center by serine (Pro132Ser) restores sensitivity to 6-propyl-2-thiouracil. (2006) (41)
- Enterohepatic circulation of triiodothyronine (T3) in rats: importance of the microflora for the liberation and reabsorption of T3 from biliary T3 conjugates. (1989) (41)
- Characterization of a propylthiouracil-insensitive type I iodothyronine deiodinase. (1997) (41)
- Athyroid Pax8-/- mice cannot be rescued by the inactivation of thyroid hormone receptor alpha1. (2005) (41)
- Mechanism of action of iodothyronine-5'-deiodinase. (1979) (41)
- Women with high early pregnancy urinary iodine levels have an increased risk of hyperthyroid newborns: the population‐based Generation R Study (2014) (41)
- Characterization of iodothyronine sulfotransferase activity in rat liver. (1997) (40)
- Effect of cold exposure on the hypothalamic release of thyrotropin-releasing hormone and catecholamines. (1991) (39)
- The effect of genetic variation in the type 1 deiodinase gene on the interindividual variation in serum thyroid hormone levels: an investigation in healthy Danish twins (2009) (39)
- Levels of dopamine and thyrotrophin-releasing hormone in hypophysial stalk blood during an oestrogen-stimulated surge of prolactin in the ovariectomized rat. (1985) (39)
- Thyrotropin-releasing hormone (TRH)-immunoreactive neuron population in the rat olfactory bulb (1988) (39)
- Thyroid function and outcome in children who survived meningococcal septic shock (2005) (39)
- Uptake of thyroxine in cultured anterior pituitary cells of euthyroid rats. (1994) (39)
- Regulation of TSH secretion and thyroid function in Cushing's disease. (1981) (39)
- Childhood Thyroid Function Reference Ranges and Determinants: A Literature Overview and a Prospective Cohort Study. (2017) (38)
- Accumulation of plasma triiodothyronine sulfate in rats treated with propylthiouracil. (1987) (38)
- Evaluation in vitro and in rats of161Tb-DTPA-octreotide, a somatostatin analogue with potential for intraoperative scanning and radiotherapy (1995) (38)
- Thyroid hormone transporters and deiodinases in the developing human hypothalamus. (2012) (37)
- Coexistence of TRH with other neuroactive substances in the rat central nervous system. (1988) (37)
- Long-term toxicity of [177Lu-DOTA0,Tyr3]octreotate in rats (2007) (37)
- Therapeutic applications of thyroid hormone analogues in resistance to thyroid hormone (RTH) syndromes (2017) (37)
- Differential effects of maternal dexamethasone treatment on circulating thyroid hormone concentrations and tissue deiodinase activity in the pregnant ewe and fetus. (2007) (37)
- Use of the rat pancreatic CA20948 cell line for the comparison of radiolabelled peptides for receptor-targeted scintigraphy and radionuclide therapy (2000) (37)
- Changes within the thyroid axis during the course of critical illness. (2006) (37)
- The Metabolism and Dechlorination of Chlorotyrosine in Vivo* (2007) (37)
- Rat liver type I iodothyronine deiodinase is not identical to protein disulfide isomerase. (1989) (36)
- Identification and consequences of polymorphisms in the thyroid hormone receptor alpha and beta genes. (2008) (36)
- Expression of rat liver cell membrane transporters for thyroid hormone in Xenopus laevis oocytes. (1997) (36)
- Effects of inhibition of type I iodothyronine deiodinase and phenol sulfotransferase on the biliary clearance of triiodothyronine in rats. (1988) (36)
- The role of Arg445 and Asp498 in the human thyroid hormone transporter MCT8. (2014) (36)
- A nonselenoprotein from amphioxus deiodinates triac but not T3: is triac the primordial bioactive thyroid hormone? (2011) (36)
- Fatigue and fatigue-related symptoms in patients treated for different causes of hypothyroidism. (2012) (35)
- Stimulation of Thyroid Function by Human Chorionic Gonadotropin During Pregnancy: A Risk Factor for Thyroid Disease and a Mechanism for Known Risk Factors. (2017) (35)
- In vivo release of dopamine, luteinizing hormone-releasing hormone and thyrotropin-releasing hormone in male rats bearing a prolactin-secreting tumor. (1987) (35)
- Mutations in MCT8 in patients with Allan-Herndon-Dudley-syndrome affecting its cellular distribution. (2013) (35)
- A new radioimmunoassay of thyrotropin‐releasing hormone (1977) (35)
- Studies on the role of TRH and corticosterone in the regulation of prolactin and thyrotrophin secretion during lactation. (1996) (34)
- Characteristics and thyroid state-dependent regulation of iodothyronine deiodinases in pigs. (2004) (34)
- On the enterohepatic cycle of triiodothyronine in rats; importance of the intestinal microflora. (1989) (34)
- Uptake of 3,3',5,5'-tetraiodothyroacetic acid and 3,3',5'-triiodothyronine in cultured rat anterior pituitary cells and their effects on thyrotropin secretion. (1995) (34)
- Characterization of rat iodothyronine sulfotransferases. (2003) (34)
- Radiolabelled regulatory peptides for imaging and therapy. (2007) (34)
- Increased plasma 3,5,3'-triiodothyronine sulfate in rats with inhibited type I iodothyronine deiodinase activity, as measured by radioimmunoassay. (1989) (33)
- Clinical Consequences of Mutations in Thyroid Hormone Receptor-α1 (2014) (33)
- Triiodothyroacetic acid in health and disease. (2017) (33)
- Daily variations in type II iodothyronine deiodinase activity in the rat brain as controlled by the biological clock. (2005) (33)
- Relevance of Different Cellular Models in Determining the Effects of Mutations on SLC16A2/MCT8 Thyroid Hormone Transporter Function and Genotype–Phenotype Correlation (2013) (32)
- Transport and metabolism of iodothyronines in cultured human hepatocytes. (1993) (32)
- Sorafenib induced thyroiditis in two patients with hepatocellular carcinoma. (2011) (32)
- Transport of thyroid hormones is selectively inhibited by 3-iodothyronamine. (2010) (32)
- Structure-Activity Relationships for Thyroid Hormone Deiodination by Mammalian Type I Iodothyronine Deiodinases1. (1997) (32)
- Placental Angiogenic Factors Are Associated With Maternal Thyroid Function and Modify hCG-Mediated FT4 Stimulation. (2015) (31)
- Metabolism of reverse triiodothyronine by isolated rat hepatocytes. (1987) (31)
- The type 2 deiodinase ORFa-Gly3Asp polymorphism (rs12885300) influences the set point of the hypothalamus-pituitary-thyroid axis in patients treated for differentiated thyroid carcinoma. (2011) (31)
- Thyroid hormone signaling. (2013) (31)
- Evidence for a homodimeric structure of human monocarboxylate transporter 8. (2009) (31)
- Selenouracil derivatives are potent inhibitors of the selenoenzyme type I iodothyronine deiodinase. (1992) (31)
- Tissue mRNA expression of the glucocorticoid receptor and its splice variants in fatal critical illness (2009) (31)
- Age-related changes in renal and hepatic cellular mechanisms associated with variations in rat serum thyroid hormone levels. (2008) (31)
- Genetic variation in thyroid hormone transporters. (2007) (31)
- Thyroid hormone transporters and resistance. (2013) (30)
- Effect of suckling on the in vivo release of thyrotropin-releasing hormone, dopamine and adrenaline in the lactating rat. (1988) (30)
- One enzyme for the 5'-deiodination of 3,3',5'-triiodothyronine and 3',5'-diiodothyronine in rat liver. (1982) (30)
- Thyroid hormone transport by the heterodimeric human system L amino acid transporter. (2001) (30)
- Thyrotropin acts as a T-cell developmental factor in mice and humans. (2014) (30)
- Structure-activity relationships for thyroid hormone deiodination by mammalian type I iodothyronine deiodinases. (1997) (30)
- The essential role of albumin in the active transport of thyroid hormones into primary cultured rat hepatocytes (1979) (29)
- Clinical and Molecular Characteristics of SLC16A2 (MCT8) Mutations in Three Families with the Allan–Herndon–Dudley Syndrome (2017) (29)
- Polychlorinated biphenyl exposure and deiodinase activity in young infants. (2017) (29)
- Cellular Uptake of Thyroid Hormones (2016) (29)
- Cloning and Characterization of Type III Iodothyronine Deiodinase from the Fish Oreochromis niloticus. (1999) (29)
- Thyroid hormone receptor isoform expression in livers of critically ill patients. (2007) (29)
- Expression of pituitary hormones in the Pax8-/- mouse model of congenital hypothyroidism. (2004) (29)
- Monocarboxylate Transporter 8 Modulates the Viability and Invasive Capacity of Human Placental Cells and Fetoplacental Growth in Mice (2013) (29)
- Human chorionic gonadotropin (hCG) concentrations during the late first trimester are associated with fetal growth in a fetal sex-specific manner (2016) (29)
- Expression of glucocorticoid, retinoid, and thyroid hormone receptors during human lung development. (2005) (28)
- The Risk of Preeclampsia According to High Thyroid Function in Pregnancy Differs by hCG Concentration. (2016) (28)
- Solubilization and partial characterization of rat liver iodothyronine deiodinases. (1980) (28)
- Plasma membrane transport of thyroid hormone: its possible pathophysiological significance (1983) (28)
- The association of maternal thyroid function with placental hemodynamics (2017) (28)
- Thyroid hormone synthesis, plasma membrane transport and metabolism (1997) (28)
- A child with a deletion in the monocarboxylate transporter 8 gene: 7-year follow-up and effects of thyroid hormone treatment. (2011) (28)
- RESPONSE TO THYROTROPHIN‐RELEASING HORMONE AND TRIIODOTHYRONINE SUPPRESSIBILITY IN EUTHYROID MULTINODULAR GOITRE (1977) (27)
- Substitution of cysteine for a conserved alanine residue in the catalytic center of type II iodothyronine deiodinase alters interaction with reducing cofactor. (2002) (27)
- Expression of chicken hepatic type I and type III iodothyronine deiodinases during embryonic development. (1997) (27)
- Maternal Hypothyroxinemia During Pregnancy and Growth of the Fetal and Infant Head (2012) (27)
- Essentials of peptide receptor scintigraphy with emphasis on the somatostatin analog octreotide. (1994) (27)
- High free thyroxine levels are associated with QTc prolongation in males. (2008) (27)
- Thyroid Hormone Transporters MCT8 and OATP1C1 Control Skeletal Muscle Regeneration (2018) (26)
- Effects of substitution and high-dose thyroid hormone therapy on deiodination, sulfoconjugation, and tissue thyroid hormone levels in prolonged critically ill rabbits. (2008) (26)
- Differential expression and ciprofibrate induction of hepatic UDP-glucuronyltransferases for thyroxine and triiodothyronine in Fischer rats. (1991) (26)
- Maternal total T4 during the first half of pregnancy: physiologic aspects and the risk of adverse outcomes in comparison with free T4 (2016) (26)
- Evidence for a single enzyme in rat liver catalysing the deiodination of the tyrosyl and the phenolic ring of iodothyronines. (1982) (26)
- Regulation of the active transport of 3,3′,5‐triiodothyronine (T3) into primary cultured rat hepatocytes by ATP (1980) (26)
- Different causes of Reduced Sensitivity to Thyroid Hormone: Diagnosis and Clinical management (2013) (26)
- A new radiolabelled somatostatin analogue [111In-DTPA-D-Phe1]RC-160: preparation, biological activity, receptor scintigraphy in rats and comparison with [111In-DTPA-D-Phe1]octreotide (1994) (26)
- Characteristics of type III iodothyronine deiodinase. (1992) (26)
- Long-term toxicity of [(177)Lu-DOTA (0),Tyr (3)]octreotate in rats. (2007) (25)
- Hypothyroidism compromises hypothalamic leptin signaling in mice. (2013) (25)
- Inhibition of uptake of thyroid hormone into rat hepatocytes by preincubation with N-bromoacetyl-3,3',5-triiodothyronine. (1988) (25)
- Thyroid hormone transport by the rat fatty acid translocase. (2003) (25)
- Regulation of hypothalamic TRH production and release in the rat. (1992) (25)
- Selective modification of the active center of renal iodothyronine 5'-deiodinase by iodoacetate. (1984) (25)
- Rapid glucuronidation of tri- and tetraiodothyroacetic acid to ester glucuronides in human liver and to ether glucuronides in rat liver. (1994) (25)
- Deafness and loss of cochlear hair cells in the absence of thyroid hormone transporters Slc16a2 (Mct8) and Slc16a10 (Mct10) (2018) (25)
- An ascidian homolog of vertebrate iodothyronine deiodinases. (2004) (25)
- Characterization of Chicken Thyroid Hormone Transporters. (2016) (25)
- The effects of 1,25-dihydroxyvitamin D3 on growth, alkaline phosphatase and adenylate cyclase of rat osteoblast-like cells. (1986) (24)
- The role of dietary fat in peripheral thyroid hormone metabolism. (1980) (24)
- Thyroid hormones and their placental deiodination in normal and pre-eclamptic pregnancy. (2013) (24)
- Thyroid disorders in older adults. (2013) (24)
- Thyrotropin-releasing hormone (TRH)-immunoreactive boutons and nerve cell bodies in the dorsal horn of the cat L7 spinal cord (1987) (24)
- Investigation of type I and type III iodothyronine deiodinases in rat tissues using N-bromoacetyl-iodothyronine affinity labels (1995) (24)
- Effects of Thyrotropin on Peripheral Thyroid Hormone Metabolism and Serum Lipids. (2018) (24)
- Further Insights into the Allan-Herndon-Dudley Syndrome: Clinical and Functional Characterization of a Novel MCT8 Mutation (2015) (24)
- Bioactivation of dibrominated biphenyls by cytochrome P450 activity to metabolites with estrogenic activity and estrogen sulfotransferase inhibition capacity. (2005) (24)
- Thyrotropin, but not a polymorphism in type II deiodinase, predicts response to paroxetine in major depression. (2006) (24)
- Pre-clinical evaluation of [(111)In-DTPA-Pro(1), Tyr(4)]bombesin, a new radioligand for bombesin-receptor scintigraphy. (2000) (23)
- Importance of His192 in the human thyroid hormone transporter MCT8 for substrate recognition. (2013) (23)
- Thyroid hormone metabolism : molecular biology and alternate pathways (1994) (23)
- Consumptive hypothyroidism: a case report and review of the literature (2011) (23)
- The influence of albumin on vitamin D metabolism in fetal chick osteoblast-like cells. (1984) (23)
- Thyroid Function and Premature Delivery in TPO Antibody‐Negative Women: The Added Value of hCG (2017) (23)
- Role of sulfate in thyroid hormone sulfation. (1996) (23)
- Pituitary and extrapituitary action sites of the novel nonpeptidyl growth hormone (GH) secretagogue L-692,429 in the chicken. (1998) (23)
- Regulation of influx and efflux of thyroid hormones in rat hepatocytes: possible physiologic significance of the plasma membrane in the regulation of thyroid hormone activity. (1984) (23)
- Handling of iodothyronines by the liver and kidney in patients with chronic liver disease. (1987) (22)
- Thyrotrophin-releasing hormone inactivation by human postmortem brain (1985) (22)
- Thyrotropin releasing hormone (TRH)-immunoreactive cell groups in the rat central nervous system (2004) (22)
- Transcriptional profiling of fibroblasts from patients with mutations in MCT8 and comparative analysis with the human brain transcriptome (2010) (22)
- Cloning and characterization of type III iodothyronine deiodinase from the fish Oreochromis niloticus. (1999) (22)
- Diverse Genotypes and Phenotypes of Three Novel Thyroid Hormone Receptor [alpha] Mutations (2015) (22)
- Determinants of Polychlorinated Biphenyls (PCBs) in Human Milk (1988) (22)
- Interlaboratory Variation of Vitamin D Metabolite Measurements (1982) (22)
- Molecular basis for the substrate selectivity of cat type I iodothyronine deiodinase. (2003) (22)
- Genetics of thyroid function. (2017) (22)
- Somatostatin receptor scintigraphy using [111In-DTPA0]RC-160 in humans: a comparison with [111In-DTPA0]octreotide (1998) (21)
- Gender-specific changes in thyroid hormone-glucuronidating enzymes in rat liver during short-term fasting and long-term food restriction. (1996) (21)
- Risk factors and a clinical prediction model for low maternal thyroid function during early pregnancy: two population‐based prospective cohort studies (2016) (21)
- Spatial and Temporal Expression of Glucocorticoid, Retinoid, and Thyroid Hormone Receptors Is Not Altered in Lungs of Congenital Diaphragmatic Hernia (2006) (21)
- Effects of a furan fatty acid and indoxyl sulfate on thyroid hormone uptake in cultured anterior pituitary cells. (1995) (21)
- Specific binding sites for L-triiodothyronine in rat liver and kidney cytosol. (1976) (21)
- Radio-immunoassay of thyroxine in unextracted serum. (1975) (21)
- Metabolism of 3,3'-diiodothyronine in rat hepatocytes: interaction of sulfation with deiodination. (1984) (21)
- Approaches to a markedly increased sensitivity of the radioimmunoassay for thyrotropin-releasing hormone by derivatization. (1981) (20)
- Radioimmunoassay of 3,3'-di-iodothyronine in unextracted serum: the effect of endogenous tri-iodothyronine. (1978) (20)
- Thyroid Hormone Metabolism and the Developing Human Lung (2001) (20)
- Mechanism of inhibition of iodothyronine-5'-deiodinase by thioureylenes and sulfite. (1980) (20)
- Deiodination of thyroid hormone and the role of glutathione (1980) (20)
- Thyroid function in short children born small‐for‐gestational age (SGA) before and during GH treatment (2008) (20)
- Renal clearance of the thyrotropin-releasing hormone-like peptide pyroglutamyl-glutamyl-prolineamide in humans. (1997) (20)
- Impact of thyroid function and polymorphisms in the type 2 deiodinase on blood pressure: the Rotterdam Study and the Rotterdam Scan Study (2009) (19)
- Transmitter expression and morphological development of embryonic medullary and mesencephalic raphé neurones after transplantation to the adult rat central nervous system (1988) (19)
- Partial purification of the microsomal rat liver iodothyronine deiodinase II. Affinity chromatography (1988) (19)
- Lowering of serum 3,3‘,5‐triiodothyronine thyroxine ratio in patients with myocardial infarction; relationship with extent of tissue injury (1978) (19)
- Induction of type 1 iodothyronine deiodinase expression inhibits proliferation and migration of renal cancer cells (2017) (19)
- Effects of thyroid hormone transporters MCT8 and MCT10 on nuclear activity of T3 (2016) (19)
- Uptake of triiodothyronine and triiodothyroacetic acid in neonatal rat cardiomyocytes: effects of metabolites and analogs. (2002) (19)
- Radioiodinated somatostatin analogue RC-160: preparation, biological activity, in vivo application in rats and comparison with [123I-Tyr3]octreotide (1993) (19)
- Sex differences in long-term stress-induced colonic, behavioural and hormonal disturbances. (1999) (18)
- Substrate requirement for inactivation of iodothyronine-5'-deiodinase activity by thiouracil. (1981) (18)
- Metabolism of triiodothyroacetic acid (TA3) in rat liver. I. Deiodination of TA3 and TA3 sulfate by microsomes. (1989) (18)
- Underestimation of effect of thyroid function parameters on morbidity and mortality due to intra-individual variation. (2011) (18)
- Hydrolysis of iodothyronine glucuronides by obligately anaerobic bacteria isolated from human faecal flora (1986) (18)
- Thyrotropin‐releasing hormone (TRH)‐like immunoreactivity in the grey monkey (Macaca fascicularis) spinal cord and medulla oblongata with special emphasis on the bulbospinal tract (1992) (18)
- Soluble Flt1 and placental growth factor are novel determinants of newborn thyroid (dys)function: the generation R study. (2014) (18)
- Regulation of thyrotropin-releasing hormone in the posterior pituitary. (1995) (17)
- Metabolism of thyroid hormones in cultured cardiac fibroblasts of neonatal rats. (2002) (17)
- Partial purification of the microsomal rat liver iodothyronine deiodinase I. Solubilization and ion-exchange chromatography (1988) (17)
- Rapid and bacteria-dependent in vitro hydrolysis of iodothyronine-conjugates by intestinal contents of humans and rats. (1986) (17)
- Tissue distribution and metabolism of radioiodinated DTPA0, D-Tyr1 and Tyr3 derivatives of octreotide in rats. (1998) (17)
- Thyroid status in a large cohort of patients with mental retardation: the TOP‐R (Thyroid Origin of Psychomotor Retardation) study (2011) (17)
- Regulation of the Release of TSH (1985) (17)
- Psychomotor Retardation Caused by a Defective Thyroid Hormone Transporter: Report of Two Families with Different MCT8 Mutations (2014) (17)
- MCT8 is Downregulated by Short Time Iodine Overload in the Thyroid Gland of Rats (2015) (17)
- The metabolism and de-bromination of bromotyrosine in vivo (2016) (17)
- Iodine-131 labelled octreotide: not an option for somatostatin receptor therapy (1996) (16)
- Thyrotropin-releasing hormone gene expression by anterior pituitary cells in long-term cultures is influenced by the culture conditions and cell-to-cell interactions. (1997) (16)
- Changes within the thyroid axis after long‐term TSH‐suppressive levothyroxine therapy (2012) (16)
- Transmitter expression and morphological development of embryonic medullary and mesencephalic raph 6 neurones after transplantation to the adult rat central nervous system I . Grafts to the spinal cord (16)
- The combined use of immunohistochemistry and intracellular staining with horseradish peroxidase for light and electron microscopic studies of transmitter-identified inputs to functionally characterized neurons (1987) (16)
- Properties of detergent-dispersed iodothyronine 5- and 5'-deiodinase activities from rat liver. (1983) (16)
- Thyroid over-expression of type 1 and type 2 deiodinase may account for the syndrome of low thyroxine and increasing triiodothyronine during propylthiouracil treatment. (2003) (16)
- Degradation of thyrotropin releasing hormone and a related compound by rat liver and kidney homogenate. (1976) (16)
- Regulation of prolactin secretion in patients with Cushing's disease. A comparative study on the effects of dexamethasone, lysine vasopressin and ACTH on prolactin secretion by the rat pituitary gland in vitro. (1981) (15)
- The elemental importance of sufficient iodine intake: a trace is not enough. (2006) (15)
- Comparison of uptake of99mTc-MIBI,99mTc-tetrofosmin and99mTc-012 into human breast cancer cell lines (1996) (15)
- Transient hypothyroxinaemia in preterm infants (2001) (15)
- Comparison of uptake of 99mTc-MIBI, 99mTc-tetrofosmin and 99mTc-Q12 into human breast cancer cell lines. (1996) (15)
- Enzymic formation of TRH-OH from TRH by rat hypothalamus (1980) (15)
- Production and characterization of monoclonal and polyclonal antibodies against thyrotropin-releasing hormone. (1995) (15)
- Effects of Chemical Chaperones on Thyroid Hormone Transport by MCT8 Mutants in Patient-Derived Fibroblasts (2018) (15)
- Importance of cysteine residues in the thyroid hormone transporter MCT8. (2013) (15)
- Regulation of the TRH-like peptide pyroglutamyl-glutamyl-prolineamide in the rat anterior pituitary gland. (1995) (15)
- Multiple effects of cold exposure on livers of male mice. (2018) (14)
- Outward‐Open Model of Thyroid Hormone Transporter Monocarboxylate Transporter 8 Provides Novel Structural and Functional Insights (2017) (14)
- In vivo hypothalamic release of thyrotropin-releasing hormone after electrical stimulation of the paraventricular area: comparison between push-pull perfusion technique and collection of hypophysial portal blood. (1989) (14)
- Thyroid hormone responsiveness in N-Tera-2 cells. (2003) (14)
- Regulation of Thyroid Function, Synthesis and Function of Thyroid Hormones (2018) (14)
- Characterization of iodothyronine outer ring and inner ring deiodinase activities in the blue tilapia, Oreochromis aureus. (1997) (14)
- Studies on radiolabeled somatostatin analogues in rats and in patients. (1996) (14)
- Inactivation of thyrotrophin releasing hormone by human and rat serum. (1977) (14)
- Metabolism of triiodothyroacetic acid (TA3) in rat liver. II. Deiodination and conjugation of TA3 by rat hepatocytes and in rats in vivo. (1989) (14)
- Finding the way into the brain without MCT8. (2012) (14)
- Inhibition of pituitary type 2 deiodinase by reverse triiodothyronine does not alter thyroxine-induced inhibition of thyrotropin secretion in hypothyroid rats. (2005) (14)
- Binding of L-triiodothyronine to isolated rat liver and kidney nuclei under various circumstances. (1976) (14)
- Chronic infusion of TNF-alpha reduces plasma T4 binding without affecting pituitary-thyroid activity in rats. (1992) (13)
- Tissue-specific effects of mutations in the thyroid hormone transporter MCT8. (2011) (13)
- Inhibitory effects of calcium channel blockers on thyroid hormone uptake in neonatal rat cardiomyocytes. (2001) (13)
- Isolated GH deficiency: mutation screening and copy number analysis of HMGA2 and CDK6 genes. (2011) (13)
- Anemia in Patients With Resistance to Thyroid Hormone α: A Role for Thyroid Hormone Receptor α in Human Erythropoiesis (2017) (13)
- Identification of 3,5-diiodo-L-thyronine-binding proteins in rat liver cytosol by photoaffinity labeling. (2003) (13)
- Inhibition of iodothyronine deiodinase by phenolphthalein dyes (1982) (13)
- Sorafenib-Induced Changes in Thyroid Hormone Levels in Patients Treated for Hepatocellular Carcinoma (2017) (13)
- Effect of ketoconazole on metabolism and binding of 1,25-dihydroxyvitamin D-3 by intact rat osteogenic sarcoma cells. (1987) (13)
- The Role of Arg 445 and Asp 498 in the Human Thyroid Hormone Transporter MCT 8 (2014) (12)
- A radioimmunoassay for the measurement of pyroglutamyl-histidyl-proline, a proposed thyrotropin releasing hormone metabolite. (1975) (12)
- Thyroid hormone transport across the placenta. (2016) (12)
- Expression of recombinant membrane-bound type I iodothyronine deiodinase in yeast. (2005) (12)
- Dissociation and association between calcitonin and adrenocorticotropin secretion. (1980) (12)
- High serum levels of the thyrotropin-releasing hormone-like peptide pyroglutamyl-glutamyl-prolineamide in patients with carcinoid tumors. (1996) (12)
- Radioimmunoassay of thyrotrophin releasing hormone (TRH). (1974) (12)
- Genetic screening of regulatory regions of pituitary transcription factors in patients with idiopathic pituitary hormone deficiencies (2017) (12)
- Hepatic metabolism, biliary clearance and enterohepatic circulation of thyroid hormone. (1988) (12)
- Rapid sulfation of 3,3',5'-triiodothyronine in native Xenopus laevis oocytes. (1998) (12)
- Deiodination of iodothyronine sulfamates by type I iodothyronine deiodinase of rat liver. (1991) (12)
- Reaction of the type III iodothyronine deiodinase with the affinity label N‐bromoacetyl‐triiodothyronine (1993) (12)
- Urinary excretion of the TRH-like peptide pyroglutamyl-glutamyl-prolineamide in rats. (1997) (12)
- Serum thyrotrophin concentration: an unreliable test for detection of early hypothyroidism after thyroidectomy. (1975) (12)
- [Cardiovascular effects of hypothyroidism]. (2000) (12)
- Neural differentiation of the human neuroblastoma cell line IMR32 induces production of a thyrotropin-releasing hormone-like peptide (1994) (11)
- Thyrotropin-releasing hormone (TRH)-immunoreactive neuron populations in the rat olfactory bulb. (1988) (11)
- Functional Characterization of Xenopus Thyroid Hormone Transporters mct8 and oatp1c1 (2017) (11)
- Possible role of corticosterone in the down-regulation of the hypothalamo-hypophysial-thyroid axis in streptozotocin-induced diabetes mellitus in rats. (1997) (11)
- Functional analysis of novel genetic variation in the thyroid hormone activating type 2 deiodinase. (2014) (11)
- The thyroid hormone transporters MCT8 and MCT10 transport the affinity-label N-bromoacetyl-[125I]T3 but are not modified by it (2011) (11)
- Binding of radioiodinated propylthiouracil to rat liver microsomal fractions. Stimulation by substrates for iodothyronine 5'-deiodinase. (1979) (11)
- Uptake of triiodothyronine sulfate and suppression of thyrotropin secretion in cultured anterior pituitary cells. (1994) (10)
- The Thyroid Axis ‘Setpoints’ are Significantly Altered After Long-Term Suppressive LT4 Therapy (2014) (10)
- Modulation by epidermal growth factor of the basal 1,25(OH)2D3 receptor level and the heterologous up-regulation of the 1,25(OH)2D3 receptor in clonal osteoblast-like cells (2007) (10)
- Cloning of Tilapia Type I and III Deiodinases a (1998) (10)
- Effects of thyroid state on the expression of hepatic thyroid hormone transporters in rats. (2002) (10)
- Chapter 6 Metabolism of thyroid hormone (1988) (10)
- Thyroid State Regulates Gene Expression in Human Whole Blood (2018) (10)
- Differential sensitivity of brain iodothyronine 5'-deiodinases to sulfhydryl-blocking reagents (1983) (10)
- Thyroid function: Thyroid dysfunction and breast cancer risk — an unfinished story (2016) (10)
- Hepatobiliary handling of iodine-125-Tyr3-octreotide and indium-111-DTPA-D-Phe1-octreotide by isolated perfused rat liver. (1993) (10)
- Follow-up of long-term treatment of predialysis renal bone disease with 1-alpha-hydroxy-derivatives of vitamin D. (1983) (9)
- Quantification of type III iodothyronine deiodinase activity using thin-layer chromatography and phosphor screen autoradiography. (1993) (9)
- Seasonal fluctuations in serum concentrations of vitamin D metabolites in normal subjects. (1981) (9)
- The effects of histidyl-proline-diketopiperazine, a metabolite of TRH, on prolactin release by the rat pituitary gland in vitro. (1981) (9)
- Preparation of radioiodine labelled thiouracil derivatives (1981) (9)
- Replacement therapy with L-thyroxine: serum thyroid hormone and thyrotropin levels in hypothyroid patients changing from desiccated thyroid to pure thyroxine substitution therapy. (1981) (9)
- Role of the Bile Acid Transporter SLC10A1 in Liver Targeting of the Lipid‐Lowering Thyroid Hormone Analog Eprotirome (2017) (9)
- TRH-like immunoreactivity in endocrine cells and neurons in the gastro-intestinal tract of the rat and guinea pig (1988) (8)
- Effects of methimazole on the elimination of irinotecan (2010) (8)
- Single‐nucleotide variants in two Hedgehog genes, SHH and HHIP, as genetic cause of combined pituitary hormone deficiency (2013) (8)
- In vitro characterization of human, mouse and zebrafish MCT8 orthologues. (2019) (8)
- Thyroid hormone signaling in the hypothalamus (2008) (8)
- In vitro and mouse studies support therapeutic utility of triiodothyroacetic acid in MCT8 deficiency. (2015) (8)
- Hydrolysis of iodothyronine sulfates by sulfatase activity of anaerobic bacteria from the rat intestinal flora (1985) (8)
- Comparative aspects of brain TRH inactivation in different vertebrate species. (1982) (8)
- A large-scale population-based analysis of common genetic variation in the thyroid hormone receptor alpha locus and bone. (2012) (8)
- Serum microRNA profiles in athyroid patients on and off levothyroxine therapy (2018) (8)
- LACK OF RESPONSE OF 1,25‐DIHYDROXYCHOLECALCIFEROL TO EXOGENOUS PARATHYROID HORMONE IN A PATIENT WITH TREATED PSEUDOHYPOPARATHYROIDISM (1981) (8)
- Unique near-complete deletion of GLI2 in a patient with combined pituitary hormone deficiency and post-axial polydactyly. (2019) (7)
- International survey of the radioimmunological measurement of serum reverse triiodothyronine. (1980) (7)
- Growth hormone insensitivity syndrome caused by a heterozygous GHR mutation: phenotypic variability owing to moderation by nonsense‐mediated decay (2012) (7)
- Effects of 5,5'-diphenylhydantoin on the metabolic pathway of thyroid hormone in rats. (1997) (7)
- Effects of ligand priming and multiple-dose injection on tissue uptake of 111In-pentetreotide in rats. (1997) (7)
- Effect of Aroclor 1254 on thyroid hormone sulfation in fetal rats. (1998) (7)
- Selective inhibition of glucuronidation by 2,2,2-triphenylethyl-UDP in isolated rat hepatocytes: conjugation of harmol, 3,3',5-triiodothyronine, and N-hydroxy-2-acetylaminofluorene. (1991) (7)
- Triiodothyroacetic Acid Treatment in MCT8 Deficiency: A Word of Nuance. (2016) (7)
- Iodothyronine sulfate‐hydrolyzing anaerobic bacteria isolated from human fecal flora (1985) (7)
- Association of antiepileptic drug usage, trace elements and thyroid hormone status. (2016) (7)
- Childhood thyroid function, body composition and cardiovascular function. (2017) (6)
- The Association of Thyroid Function With Maternal and Neonatal Homocysteine Concentrations (2017) (6)
- The Association of Thyroid Function With Bone Density During Childhood (2018) (6)
- Thyroid function and deiodinase activities in rats with marginal iodine deficiency (1994) (6)
- Effect of thyrotropin-releasing hormone and its metabolites on the secretion of sulfated polysaccharides by foot integument of a pond snail. (1984) (6)
- Regulation of thyroid hormone bioactivity. (1986) (6)
- Independence of hyperleptinemia-induced fat disappearance from thyroid hormone. (2004) (6)
- Transport of thyroxine and 3,3',5-triiodothyronine in human umbilical vein endothelial cells. (2009) (6)
- Consequences of brain-specific thyroid hormone deprivation in MCT8/OATP1C1 double knockout mice (2012) (6)
- The influence of caloric restriction on serum prolactin. (1979) (6)
- MCT8: from gene to disease and therapeutic approach. (2011) (6)
- Enkephalin-, thyrotropin-releasing hormone- and substance P-immunoreactive axonal innervation of the ventrolateral dendritic bundle in the cat sacral spinal cord: An ultrastructural study (1994) (6)
- Sulfation facilitates hepatic deiodination of iodothyronines. (1984) (6)
- Genetic analysis of IRF6, a gene involved in craniofacial midline formation, in relation to pituitary and facial morphology of patients with idiopathic growth hormone deficiency (2017) (5)
- Seasonal fluctuations in serum concentrations of vitamin D metabolites (1982) (5)
- Left ventricular myocardial infarction in mice induces sustained cardiac deiodinase type III activity (2008) (5)
- Study on the enzymatic 5'-deiodination of 3',5'-diiodothyronine using a radioimmunoassay for 3'-iodothyronine. (1980) (5)
- Transmitter expression and morphological development of embryonic medullary and mesencephalic raphé neurones after transplantation to the adult rat central nervous system (2004) (5)
- The pyriproxyfen metabolite 4’OH- pyriproxyfen disrupts thyroid hormone signaling and enhances Musashi-1 levels in neuroprogenitors (2018) (5)
- Chapter 95 – Resistance to Thyroid Hormone∗ (2016) (5)
- Production and characterization of antisera to synthetic 1-34 human parathyroid hormone fragments: possible implications for the correctness of proposed structures. (1979) (5)
- Psychological wellbeing correlates with free T4 but not free T3 levels in patients on adequate thyroid hormone replacement (2006) (5)
- The thyroid hormone receptor alpha locus and white matter lesions: a role for the clock gene REV-ERBα. (2012) (4)
- Hypothyroidism may account for reduced prolactin secretion in lactating rats bearing paraventricular area lesions. (1989) (4)
- Adaptive Thermogenesis Driving Catch-Up Fat Is Associated With Increased Muscle Type 3 and Decreased Hepatic Type 1 Iodothyronine Deiodinase Activities: A Functional and Proteomic Study (2021) (4)
- How specific are nuclear ‘receptors’ for thyroid hormones? (1976) (4)
- Sulfation of Thyroid Hormones (2005) (4)
- Strategy of thyroid-function testing, a comparative study using TT4, FT4I, various FT4 and IRMA-TSH kits. (1986) (4)
- Absence of TRH receptor 1 in male mice affects gastric ghrelin production. (2015) (4)
- Analysis of thyrotropin-releasing hormone-signaling components in pituitary adenomas of patients with acromegaly. (2000) (4)
- Effects of thyroid status and thyrostatic drugs on hepatic glucuronidation of lodothyronines and other substrates in rats (1996) (4)
- Identification of 3,3'-diiodothyroacetic acid sulfate: a major metabolite of 3,3',5-triiodothyronine in propylthiouracil-treated rats. (1990) (4)
- Measurement of Intracellular T3 and T3 disposal in normal subjects. (1976) (4)
- Effects of 5, 5'-diphenylhydantoin on the thyroid status in rats. (1996) (4)
- Role of Leucine 341 in Thyroid Hormone Receptor Beta Revealed by a Novel Mutation Causing Thyroid Hormone Resistance. (2018) (4)
- Is thyrotropin-releasing hormone immunoreactivity in peripheral blood an estimate for hypothalamic thyrotropin-releasing hormone release? (1992) (4)
- Immunological studies on parathyroid hormone: characterization of antisera against synthetic 1-34 human parathyroid hormone and evidence that position 30 in human parathyroid hormone is aspartic acid. (1977) (4)
- Effect of thyroid status on release of hypothalamic thyrotropin-releasing hormone. (1990) (4)
- Concomitant secretion of calcitonin, beta-endorphin and ACTH from medullary thyroid carcinoma in vivo and in vitro. (1982) (3)
- Modulating effects of thyroid state on the induction of biotransformation enzymes by 2,3,7,8-tetrachlorodibenzo-p-dioxin. (1998) (3)
- EUTHYROID HIGH TOTAL T4, NORMAL T3 SYNDROME (1979) (3)
- Multiple genomic aberrations in a patient with mental retardation and hypogonadism: 45,X/46,X,psu dic(Y) karyotype, thyroid hormone receptor beta (THRB) mutation and heterozygosity for Wilson disease (2009) (3)
- The expression of monocarboxylate transporter 8, as a specific thyroid hormone transporter in human fetal brain and placenta: the effects of intrauterine growth restriction (IUGR) (2004) (3)
- Evidence that the TRH-like peptide pyroglutamyl-glutamyl-prolineamide in human serum may not be secreted by the pituitary gland. (1997) (3)
- Diagnostic and Therapeutic Challenges in the Allan–Herndon–Dudley Syndrome (2016) (2)
- The in vitro functional impairment of thyroid hormone receptor alpha 1 isoform mutants is mainly dictated by reduced ligand-sensitivity. (2019) (2)
- Membrane transporters for thyroid hormone (2005) (2)
- European Thyroid Association: 37th Annual Meeting, Leiden, September 2013: Programme and Abstracts (2013) (2)
- [Decreased triiodothyronine (T3) production in constant reverse T3 production in advanced age]. (1979) (2)
- [Cardiovascular effects of hyperthyroidism and their treatment]. (2002) (2)
- Transmitter expression and morphological development of embryonic medullary and mesencephalic raph 6 neurones after transplantation to the adult rat central nervous system Experimental Brain Research (2)
- EUTHYROID HIGH TOTAL T4, NORMAL T3 SYNDROME (1979) (2)
- Enzymic inactivation of thyrotrophin-releasing hormone by the hypothalamus and other areas of rat brain [proceedings]. (1979) (2)
- Occasional thyroxine and triiodothyronine hypersecretion in euthyroid multinodular goitre. (1980) (2)
- Changes in the central component of the hypothalamus-pituitary-thyroid axis during Prolonged Critical Illness (2009) (2)
- Regulation of thyroid hormone metabolism during fasting and refeeding: an important role for the low Km deiodinases (1998) (2)
- Acute thyrotoxicosis in multinodular goitre. (1977) (2)
- Presence of high- and low-Km iodothyronine deiodinases in different vertebrate classes (1994) (2)
- A new radiolabelled somatostatin analogue [111In-DTPA-D-Phe1]RC-160: preparation, biological activity, receptor scintigraphy in rats and comparison with [111In-DTPA-D-Phe1]octreotide (2004) (2)
- Cloning of chicken type I and III iodothyronine deiodinases and study of their expression during embryonic liver development (1996) (2)
- The significance of plasma membrane transport of iodothyronines in the regulation of thyroid hormone bioavailability. (1988) (2)
- Acute pretranslational regulation of hepatic type III iodothyronine deiodinase by growth hormone and dexamethasone in embryonic chicken (1998) (2)
- Role of leucine 341 in thyroid hormone receptor β revealed by a novel mutation causing 1 thyroid hormone resistance 2 (2019) (1)
- The Newborn at High Risk of Brain Damage (2001) (1)
- Genetic Influences on Thyroid Function Tests (2010) (1)
- Transport of Thyroid Hormone (TH) into Hepatocytes (1989) (1)
- Thyroid hormone deiodination (1980) (1)
- Characterisation of inner and outer ring deiodinating enzymes in Oreochromis aureus (1994) (1)
- Euthyroid high total T4, normal T3 syndrome. (1979) (1)
- Cubilin and megalin in radiation-induced renal injury with labelled somatostatin analogues: are we just dealing with the kidney? (2005) (1)
- The monocarboxylate transporter 8 (MCT8) linked to human psychomotor retardation is highly expressed in thyroid hormone-sensitive neurons (2004) (1)
- Transmitter expression and morphological development of embryonic medullary and mesencephalic raph neurones after transplantation (1)
- Is transport of cortisol in liver cells carrier-mediated? (2012) (1)
- Altered thyroid hormone metabolism in the prematurely aging klotho mutant mice (2013) (1)
- The effect of MCT8 on the biological activity of T3 (2011) (1)
- Elderly Men Thyroid Hormone Concentrations , Disease , Physical Function , and Mortality in Society (2005) (1)
- Variability of phenotype in two patients with different mutations in monocarboxylate transporter 8 (2007) (1)
- Cloning of iodothyronine deiodinases from fish (1996) (1)
- Congenital hypothyroidism and partial thyroid hormone unresponsiveness of the pituitary in a patient with congenital thyroxine binding albumin elevation (1989) (1)
- Properties of antisera against synthetic 1--34 human parathyroid hormone. (1975) (1)
- 12 The Thr92Ala polymorphism in the type 2 deiodinase is not associated with thyroxin dose in athyroid patients or patients with Hashimoto thyroiditis (2009) (1)
- Monoallelic mutations in DUOXA2 are associated with mild permanent hypothyroidism and goiter (2008) (1)
- Differences in T3 uptake and metabolism in fibroblasts of MCT8 patients reflect phenotypic variability (2007) (1)
- The Role of TRH in the Regulation of Thyroid Function (1989) (1)
- Hormones, growth factors and other humoral factors (2003) (1)
- Type I iodothyronine deiodinase and PTU insensitivity (1996) (1)
- Regulation of tissue thyroid hormone levels in critical illness (2005) (1)
- Sorafenib-induced changes in thyroid hormone levels in patients with hepatocellular carcinoma (2016) (1)
- How to make a thyroid hypothyroid. (2012) (1)
- The importance of maternal thyroid for the placental function (2016) (0)
- Direct actions of T3 in proliferating chondrocytes regulate endochondral ossification and linear growth (2008) (0)
- Metabolism of Thyroid Hormone in Liver (1989) (0)
- Hypothalamic inactivation of thyrotrophin releasing hormone and one of its metabolites [proceedings]. (1979) (0)
- Additional measurement of hCG distinguishes physiological high-normal thyroid function and reveals large differences in the risk of developing preeclampsia (2016) (0)
- Serum thyroid function, mortality and disability in a cohort of 85 year olds (2016) (0)
- The Diverse Phenotype of Mutations in T 3 Receptor Alpha (TR[alpha]) (2014) (0)
- Incidence and risk factors of venous thrombosis: a prospective follow-up study (2001) (0)
- Effects of fasting and refeeding on type I and type III iodothyronine-deiodinase expression in chicken liver (1998) (0)
- Erratum to "A 28-day oral dose toxicity study enhanced to detect endocrine effects of a purified technical pentabromodiphenyl ether (pentaBDE) mixture in Wistar rats" [Toxicology 245 (2008) 109-122] (2011) (0)
- Molecular cloning of the rabbit deiodinase type I, type II and type III genes (2005) (0)
- X-LINKED PSYCHOMOTOR DELAY AND ELEVATED SERUM T3 LEVELS CAUSED BY MUTATIONS IN THE MCT8 GENE: DELINEATION OF THE CLINICAL SYNDROME (2006) (0)
- Mice deficient in the thyroid hormone transporter MCT8 exhibit tissue-specific abnormalities in thyroid hormone metabolism (2007) (0)
- Placental iodothyronine deiodinase activity across the placental bed in normotensive (NT) and pre-eclamptic (PE) pregnancies. (2011) (0)
- Re-introduction of type 1 iodothyronine deiodinase in renal cancer cells affects their migration and expression of adhesion-related genes (2015) (0)
- BIOLOGICAL ACTIVITY OF NOVEL THYROID HORMONE ANALOGUES: ROLE OF Na+ TAUROCHOLATE COTRANSPORTING POLYPEPTIDE IN LIVER SELECTIVITY (2015) (0)
- Sulfation as a Mechanism of Thyroid Hormone Metabolism (2001) (0)
- Effects of Ligand Priming and Multiple-Dose Injection Tissue Uptake of ' %-Pentetreotide in Rats on (1997) (0)
- REGULATION OF VITAMIN D ACTION IN RAT OSTEOGENIC SARCOMA CELLS (UMR-106). (1988) (0)
- Monocarboxylate Anion Transporter 8 (MCT8) Expression during Critical Illness (2007) (0)
- Increased levels of thyroid hormone and a non-suppressed TSH in two patients due to different mutations in T3 receptor beta (TR[beta]) (2008) (0)
- Cardiac induction of type III deiodinase in human ischemic heart disease (2012) (0)
- A comparison between fish, chicken and rat deiodinases (1997) (0)
- TRH inactivation by human postmortem brain (1983) (0)
- Transporter proteins specific for thyroid hormones and their agonists and antagonists (1998) (0)
- P02-23 Differential effects of GH versus IGF-1 during obesity (2012) (0)
- Comparison of 1 ! 1 In-labeled Somatostatin Analogues for Tumor Scintigraphy and Radionuclide Therapy 1 (2006) (0)
- A role for Type II Deiodinase in the Etiology of Nonthyroidal Illnes (2006) (0)
- Thyroid releasing hormone (TRH) (2004) (0)
- Iodothyronine metabolism and human brain development (2000) (0)
- Large induction of type III deiodinase (D3) expression during liver regeneration (2008) (0)
- Massive Sequencing of Thyroidal Genes Reveals Unexpected Polygenic Defects in Dyshormonogenic Hypothyroidism (2014) (0)
- Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation (2018) (0)
- Thyrotropin-releasing hormone (TRH) (2004) (0)
- European Thyroid Association: 36th Annual Meeting, Pisa, September 2012: Programme and Abstracts (2012) (0)
- Chapter 2 Genetic Influences on Thyroid Function Tests (2010) (0)
- Table 2, Missense MCT8 mutations in AHDS patients (2016) (0)
- Thyroid Hormone Analog Therapy in Patients with MCT8 deficiency: the Triac Trial (2018) (0)
- Thyroid hormones and their placental deiodination in normal and pre-eclamptic 1 pregnancy 2 (2017) (0)
- Kinetic evidence suggesting two mechanisms for iodothyronine (0)
- 297 A NON-SYNONYMOUS SNP IN GENE ASSOCIATED WITH SUSCEPTIBILITY TO SYMPTOMATIC OSTEOARTHRITIS (2007) (0)
- Clinical and expirimental neuroendocrinology (2008) (0)
- Angiogenic factors sFlt1 and PlGF are novel determinants of newborn thyroid (dys)function: the Generation R Study (2014) (0)
- Thyroid hormone transport and metabolism in mice deficient in the TH transporters Mct8 and Mct10 (2012) (0)
- The thyroidal response to hCG stimulation is impaired in women with subclinical hypothyroidism and is influenced by BMI, fetal sex and parity (2016) (0)
- Clinical application and consequences of molecular genetics of thyroid diseases (2010) (0)
- Deiodinase type II is regulated by TRα1 and expressed in pituitary thyrotrophs (2005) (0)
- Developmental control of tissue deiodinases by cortisol in fetal sheep during late gestation (2006) (0)
- Short title: Maternal iodine status and thyroid dysfunction (2013) (0)
- A New Kid on the Block: The European Thyroid Journal (2012) (0)
- Identification and functional analysis of DUOX2 variants: biallelic mutations are associated with permanent congenital hypothyroidism (2012) (0)
- Concentrations of seven iodothyronine metabolites in brain regions and the liver of the adult rat. (2002) (0)
- cardiomyocytes thyroid hormone uptake in neonatal rat Inhibitory effects of calcium channel blockers on (2001) (0)
- Anemia in PatientsWithResistance to ThyroidHormone a : A Role for Thyroid Hormone Receptor a in Human Erythropoiesis (2017) (0)
- Front & Back Matter (2012) (0)
- Thyroid hormone availability in the human fetal brain: novel entry pathways and role of radial glia (2019) (0)
- Novel entry pathways of thyroid hormones in the human fetal brain: outer and inner cerebrospinal fluid-brain barriers (2019) (0)
- Screening of IGSF1 in Patients with Central Hypothyroidism and GH Deficiency, Participating in the Dutch HYPOPIT Study (2015) (0)
- University of Groningen A meta-analysis of thyroid-related traits reveals novel loci and gender-specific differences in the regulation of thyroid function Porcu, (2013) (0)
- Two Patients with Allen-Herndon-Dudley Syndrome: a Novel Mutation on MCT8 Gene (2015) (0)
- Message from European Thyroid Association (2001) (0)
- A Warm Welcome to the ETA Annual Meeting in the Wonderful City of Leiden (2013) (0)
- D-lysine for reduction of renal[in-111-DTPA,D-phe-1 ]-octreotide and [Y-90-DOTA,D-phe-1,tyr-3]octreotide uptake (1997) (0)
- Triac: hormone, metabolite and drug. (2018) (0)
- Thyroid hormone transport and neurological development (2008) (0)
- [Hypothyroidism after subtotal strumectomy]. (1976) (0)
- Table 1, Characteristics of human thyroid hormone transporters (2016) (0)
- hCG levels are essential for the correct interpretation of gestational TSH levels: the clinical risk assessment of premature delivery (2015) (0)
- Deafness and loss of cochlear hair cells in the absence of thyroid hormone transporters Slc16a2 (Mct8) and Slc16a10 (Mct10) (2018) (0)
- Regulation of the imprinted gene type III iodothyronine deiodinase: its role in human fetal development and in disease (2005) (0)
- Free thyroxine increases the risk of AMD (2015) (0)
- Consequences of MCT8 deficiency on thyroid hormone transport in kidney and thyroid (2009) (0)
- Abnormal Thyroid Hormone Metabolism in Patients with THRA Mutations due to Impaired Expression of the Type 3 Deiodinase (2014) (0)
- EP-1629 Recalcification in lytic bone metastases of the spine after radiotherapy (2019) (0)
- Mechanism of action of rat liver enzymes catalysing the reductive deiodination of iodothyronines [proceedings]. (1979) (0)
- Immunocytochemical staining reveals localization of type I 5’-deiodinase in the follicular cells of the thyroid gland and reduced expression in thyroid carcinoma (2004) (0)
- Effectiveness and safety of the tri-iodothyronine analogue Triac in children and adults with MCT8 deficiency: an international, single-arm, open-label, phase 2 trial (2020) (0)
- Molecular cloning of the chicken type I and III iodothyronine deiodinases (1996) (0)
- Mechanisms of thyroid hormone resistance (2014) (0)
- Subject Index Vol. 68, Suppl. 5, 2007 (2007) (0)
- Importance of transporters for cellular entry of thyroid hormone (2007) (0)
- Essential role of transporters in cellular entry of thyroid hormone (2005) (0)
- 352 Serum Thyroid Hormones in Preterm Infants and Relationships to Indices of Severity of Intercurrent Illness (2005) (0)
- Comparison of 1!1In-labeled Somatostatin Analogues for Tumor Scintigraphy and Radionuclide Therapy1 (2006) (0)
- Cloning of the chicken type I and III iodothyronine deiodinases and their expression during embryonic development (1996) (0)
- Amiodarone (A) and 5'5-diphenylhydantoin (D) do not interfere with the hepatic deiodinase type I (ID-I) in vivo. (1992) (0)
- Metabolism of rT3 by Isolated Rat Hepatocytes (1986) (0)
- The significance of triiodothyronine in the evaluation of thyroid function after treatment for hyperthyroidism. (1980) (0)
- Biochemical abnormalities in MCT8 patients are due to abnormal thyroid hormone release from the thyroid and altered D1 activity (2011) (0)
- 03 Type 2 Iodothyronine Deiodinase in Human Skeletal Muscle : Effects of Hypothyroidism and Fasting (2009) (0)
- seven-year follow-up and effects of thyroid hormone treatment (2011) (0)
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