Thereza Imanishi-Kari
#23,792
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Brazilian scientist
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Thereza Imanishi-Karibiology Degrees
Biology
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Molecular Biology
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#421
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Immunology
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Biochemistry
#1583
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Biology
Thereza Imanishi-Kari's Degrees
- PhD Immunology University of São Paulo
- Bachelors Biology University of São Paulo
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Why Is Thereza Imanishi-Kari Influential?
(Suggest an Edit or Addition)According to Wikipedia, Thereza Imanishi-Kari is an associate professor of pathology at Tufts University. Her research focuses on the origins of autoimmune diseases, particularly systemic lupus erythematosus, studied using mice as model organisms. Previously she had been a faculty member at the Massachusetts Institute of Technology. She is notable for her role in what became known as the "Baltimore affair", in which a 1986 paper she co-authored with David Baltimore was the subject of research misconduct allegations. Following a series of investigations, she was fully exonerated of the charges in 1996.
Thereza Imanishi-Kari's Published Works
Published Works
- Heavy chain variable region contribution to the NPb family of antibodies: somatic mutation evident in a γ2a variable region (1981) (603)
- Analysis of the repertoire of anti‐(4‐hydroxy‐3‐nitro‐phenyl)acetyl (NP) antibodies in C 57 BL/6 mice by cell fusion. II. Characterization of idiotopes by monoclonal anti‐idiotope antibodies (1979) (234)
- Toll-like receptor 7-dependent loss of B cell tolerance in pathogenic autoantibody knockin mice. (2006) (225)
- Idiotypic analysis of the response of C57BL/6 mice to the (4‐hydroxy‐3‐nitrophenyl)acetyl group (1977) (159)
- A transgenic immunoglobulin Mu gene prevents rearrangement of endogenous genes (1985) (156)
- Class switch recombination and somatic hypermutation in early mouse B cells are mediated by B cell and Toll-like receptors. (2007) (147)
- Molecular basis of a mouse strain-specific anti-hapten response (1983) (133)
- Somatic variants of murine immunoglobulin λ light chains (1982) (109)
- T cell-independent somatic hypermutation in murine B cells with an immature phenotype. (2004) (108)
- Isolated hapten‐binding receptors of sensitized lymphocytes I. Receptors from nylon wool‐enriched mouse T lymphocyte lack serological markers of immunoglobulin constant domain but express heavy chain variable portions (1977) (91)
- Overexpression of TLR7 promotes cell-intrinsic expansion and autoantibody production by transitional T1 B cells (2013) (91)
- V region sequences of an idiotypically connected family of pathogenic anti-DNA autoantibodies. (1990) (74)
- Heavy chain variable region. Multiple gene segments encode anti-4- (hydroxy-3-nitro-phenyl)acetyl idiotypic antibodies (1985) (56)
- Isolated hapten‐binding receptors of sensitized lymphocytes. IV. Expression of immimoglobulin variable regions in (4‐hydroxy‐3‐nitrophenyl) acetyl (NP)‐specific receptors isolated from murine B and T lymphocytes (1979) (52)
- Cationic residues in pathogenic anti‐DNA autoantibodies arise by mutations of a germ‐line gene that belongs to a large VH gene subfamily (1992) (50)
- Isolated hapten-binding receptors of sensitized lymphocytes. III. Evidence for idiotypic restriction of T-cell receptors (1978) (48)
- Dosage of X‐linked Toll‐like receptor 8 determines gender differences in the development of systemic lupus erythematosus (2014) (48)
- Altered repertoire of endogenous immunoglobulin gene expression in transgenic mice containing a rearranged mu heavy chain gene (1988) (45)
- Characterization of the NPa idiotype through the analysis of monoclonal BALB/c anti‐(4‐hydroxy‐3‐nitrophenyl)acetyl (NP) antibodies (1981) (44)
- Adult bone marrow contains precursors for CD5+ B cells (1996) (37)
- Restricted association of V and J-C gene segments for mouse lambda chains. (1984) (34)
- Female Bias in Systemic Lupus Erythematosus is Associated with the Differential Expression of X-Linked Toll-Like Receptor 8 (2015) (31)
- Altered repertoire of endogenous immunoglobulin gene expression in transgenic mice containing a rearranged Mu heavy chain gene (1986) (28)
- Endogenous immunoglobulin expression in mu transgenic mice. (1991) (25)
- Production of IgG autoantibody requires expression of activation‐induced deaminase in early‐developing B cells in a mouse model of SLE (2014) (24)
- Shared idiotopes among antibodies encoded by heavy-chain variable region (VH) gene members of the J558 VH family as basis for cross-reactive regulation of clones with different antigen specificity. (1985) (24)
- The effect of an immunoglobulin μ transgene on B cell maturation (1992) (22)
- Expression of an anti‐RNA autoantibody in a mouse model of SLE increases neutrophil and monocyte numbers as well as IFN‐I expression (2014) (19)
- Cross‐reactivity of the NPa and NPb idiotypic responses of BALB/c and C57BL/6 mice to (4‐hydroxy‐3‐nitrophenyl)acetyl (NP) (1982) (17)
- Accelerated Systemic Autoimmunity in the Absence of Somatic Hypermutation in 564Igi: A Mouse Model of Systemic Lupus with Knocked-In Heavy and Light Chain Genes (2017) (12)
- Pathogenic anti-DNA autoantibodies and pathogenic autoantibody-inducing T cells. (1991) (9)
- Selective strain distribution pattern of a germline VH gene for a pathogenic anti-DNA autoantibody family. (1990) (8)
- Endogenous Ig production in mu transgenic mice. I. Allelic exclusion at the level of expression. (1993) (8)
- Production of 17.2.25 μ transgenic and endogenous immunoglobulin in X‐linked immune deficient mice (1992) (7)
- OSI's conclusions wrong (1991) (6)
- Linkage and recombination of VH gene markers, Np and Nb, in recombinant inbred strains of mice. (1981) (5)
- Endogenous Ig production in mu transgenic mice. II. Anti-Ig reactivity and apparent double allotype expression. (1993) (5)
- Restricted association of V and JC gene segments for mouse X light chains ( immunoglobulin / recombination / amino acid sequence variation / hybridoma / myeioma ) (2)
- Genetic basis for altered idiotype expression in the hyperimmune response to (4-hydroxy-3-nitrophenyl)acetyl hapten. (1986) (1)
- On the specificity of BET-1 antibody (1989) (1)
- A role for complement in the regulation of autoimmunity (2008) (1)
- Restricted association ofVandJ-Cgenesegments formouse Alight chains (1984) (0)
- Studies of immunodifferentiation using transgenic mice. (1985) (0)
- Summary of systems workshop on nitrophenyls (1981) (0)
- OR.660. Role of Complement C4 in the Regulation of Self-Reactive B Cells (2008) (0)
- Role of Complement C4 in the Regulation of Self‐Reactive B Cells (2008) (0)
- Regulation of B-cell tolerance by complement C4 (2004) (0)
- Antigens of IgM and IgG Antibodies to Diverse DNA Antibody as a Precursor for Formation Physiologically Selected Anti-Single-Stranded Domain of aHThe Rearranged (2001) (0)
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What Schools Are Affiliated With Thereza Imanishi-Kari?
Thereza Imanishi-Kari is affiliated with the following schools: