Thomas B. Kornberg
#43,538
Most Influential Person Now
American biochemist
Thomas B. Kornberg's AcademicInfluence.com Rankings
Thomas B. Kornbergbiology Degrees
Biology
#1772
World Rank
#2883
Historical Rank
#847
USA Rank
Biochemistry
#631
World Rank
#727
Historical Rank
#204
USA Rank
Molecular Biology
#749
World Rank
#766
Historical Rank
#174
USA Rank
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Biology
Thomas B. Kornberg's Degrees
- PhD Biochemistry Stanford University
- Bachelors Chemistry University of California, Berkeley
Why Is Thomas B. Kornberg Influential?
(Suggest an Edit or Addition)According to Wikipedia, Thomas Bill Kornberg is an American biochemist who was the first person to purify and characterise DNA polymerase II and DNA polymerase III. He is currently a professor of biochemistry and biophysics at the University of California, San Francisco, and is working on Drosophila melanogaster development.
Thomas B. Kornberg's Published Works
Published Works
- Crystal structure of an engrailed homeodomain-DNA complex at 2.8 Å resolution: A framework for understanding homeodomain-DNA interactions (1990) (891)
- Expression of engrailed proteins in arthropods, annelids, and chordates. (1989) (689)
- Proteolysis That Is Inhibited by Hedgehog Targets Cubitus interruptus Protein to the Nucleus and Converts It to a Repressor (1997) (687)
- Hedgehog is a signaling protein with a key role in patterning Drosophila imaginal discs (1994) (655)
- The engrailed locus of drosophila: Structural analysis of an embryonic transcript (1985) (592)
- Cytonemes Cellular Processes that Project to the Principal Signaling Center in Drosophila Imaginal Discs (1999) (574)
- Daughters against dpp modulates dpp organizing activity in Drosophila wing development (1997) (454)
- Expression of engrailed proteins in arthropods, annelids, and chordates (1989) (452)
- The engrailed locus of drosophila: In situ localization of transcripts reveals compartment-specific expression (1985) (442)
- The Drosophila hedgehog gene is expressed specifically in posterior compartment cells and is a target of engrailed regulation. (1992) (428)
- Expression of engrailed during segmentation in grasshopper and crayfish. (1989) (320)
- Engrailed: a gene controlling compartment and segment formation in Drosophila. (1981) (278)
- Creating a Drosophila wing de novo, the role of engrailed, and the compartment border hypothesis. (1995) (261)
- A DNA-unwinding protein isolated from Escherichia coli: its interaction with DNA and with DNA polymerases. (1972) (257)
- Expression of the vertebrate Gli proteins in Drosophila reveals a distribution of activator and repressor activities. (2000) (246)
- Region-specific recombination and expression are directed by portions of the Drosophila engrailed promoter. (1990) (243)
- In vitro transcription of the Drosophila engrailed gene. (1988) (234)
- FGF is an essential mitogen and chemoattractant for the air sacs of the drosophila tracheal system. (2002) (234)
- Specificity of Drosophila Cytonemes for Distinct Signaling Pathways (2011) (219)
- Analysis of DNA polymerases II and 3 in mutants of Escherichia coli thermosensitive for DNA synthesis. (1971) (217)
- Repression of ci-D in posterior compartments of Drosophila by engrailed. (1990) (211)
- Expression during embryogenesis of a mouse gene with sequence homology to the Drosophila engrailed gene (1985) (209)
- Dependence of Drosophila wing imaginal disc cytonemes on Decapentaplegic (2005) (205)
- Cytoneme-Mediated Contact-Dependent Transport of the Drosophila Decapentaplegic Signaling Protein (2014) (188)
- Cytonemes as specialized signaling filopodia (2014) (182)
- Ci: a complex transducer of the hedgehog signal. (1999) (173)
- The nucleotide sequence and the tissue-specific expression of Drosophila c-src (1985) (166)
- Isolation of cDNAs encoding the Drosophila GAGA transcription factor (1993) (161)
- Purification and DNA synthesis in cell-free extracts: properties of DNA polymerase II. (1971) (152)
- The invected gene of Drosophila: sequence analysis and expression studies reveal a close kinship to the engrailed gene. (1987) (141)
- An improved monomeric infrared fluorescent protein for neuronal and tumor brain imaging (2014) (135)
- GFP-tagged balancer chromosomes for Drosophila melanogaster (1999) (135)
- Patterns of engrailed and fushi tarazu transcripts reveal novel intermediate stages in Drosophila segmentation (1985) (131)
- A naturally-monomeric infrared fluorescent protein for protein labeling in vivo (2015) (131)
- Human BOULE gene rescues meiotic defects in infertile flies. (2003) (125)
- Compartments in the abdomen of Drosophila and the role of the engrailed locus. (1981) (122)
- Isolation of the proto-oncogene c-myb from D. melanogaster (1985) (121)
- Repression and turnover pattern fushi tarazu RNA in the early Drosophila embryo (1986) (119)
- Phosphorylation of the fused protein kinase in response to signaling from hedgehog. (1996) (117)
- Analysis of cubitus interruptus regulation in Drosophila embryos and imaginal disks. (1995) (113)
- Fly Cell Atlas: A single-nucleus transcriptomic atlas of the adult fruit fly (2022) (111)
- Regulation of cellular plasticity in Drosophila imaginal disc cells by the Polycomb group, trithorax group and lama genes (2005) (110)
- The C-terminal tail of the Hedgehog receptor Patched regulates both localization and turnover. (2006) (103)
- The Drosophila genome sequence: implications for biology and medicine. (2000) (100)
- Myoblast cytonemes mediate Wg signaling from the wing imaginal disc and Delta-Notch signaling to the air sac primordium (2015) (98)
- Deoxyribonucleic acid synthesis in cell-free extracts. IV. Purification and catalytic properties of deoxyribonucleic acid polymerase III. (1972) (94)
- Blistered: a gene required for vein/intervein formation in wings of Drosophila. (1994) (92)
- Molecular cloning of engrailed: a gene involved in the development of pattern in drosophila melanogaster (1985) (88)
- The Drosophila engrailed and invected genes: partners in regulation, expression and function. (1996) (87)
- DNA synthesis in cell-free extracts of a DNA polymerase-defective mutant. (1970) (86)
- Replication of the Escherichia coli chromosome with a soluble enzyme system. (1974) (82)
- Small nuclear RNA transcription and ribonucleoprotein assembly in early Xenopus development (1983) (80)
- Understanding the homeodomain. (1993) (77)
- Three loci related to the src oncogene and tyrosine-specific protein kinase activity in Drosophila (1983) (76)
- Visualizing Dynamics of Cell Signaling In Vivo with a Phase Separation-Based Kinase Reporter. (2018) (74)
- On the range of hedgehog signaling. (2000) (72)
- Essential basal cytonemes take up Hedgehog in the Drosophila wing imaginal disc (2017) (70)
- GFP-tagged balancer chromosomes for Drosophila melanogaster (1999) (69)
- Reduction of transcription by homologue asynapsis in Drosophila imaginal discs (1996) (66)
- Patterns of engrailed protein in early Drosophila embryos. (1989) (66)
- Cytonemes and the dispersion of morphogens (2014) (62)
- Understanding morphogen gradients: a problem of dispersion and containment. (2007) (59)
- An Essential Role for Zygotic Expression in the Pre-Cellular Drosophila Embryo (2013) (58)
- Communicating by touch--neurons are not alone. (2014) (53)
- Expression profiling of Drosophila imaginal discs (2002) (53)
- Distributing signaling proteins in space and time: the province of cytonemes. (2017) (53)
- Glutamate signaling at cytoneme synapses (2018) (51)
- Augmented noncanonical BMP type II receptor signaling mediates the synaptic abnormality of fragile X syndrome (2016) (48)
- Drosophila Signal Peptide Peptidase Is an Essential Protease for Larval Development (2005) (46)
- Designing a Green Fluorogenic Protease Reporter by Flipping a Beta Strand of GFP for Imaging Apoptosis in Animals. (2019) (44)
- Expression and targeting of Syrian hamster prion protein induced by heat shock in transgenic Drosophila melanogaster (1995) (44)
- Segmentation of the Drosophila embryo. (1993) (44)
- Hedgehog signal transduction in the posterior compartment of the Drosophila wing imaginal disc. (2000) (43)
- Tracheal branch repopulation precedes induction of the Drosophila dorsal air sac primordium. (2005) (42)
- The engrailed locus of D. melanogaster provides an essential zygotic function in precellular embryos (1985) (42)
- Organ renewal and cell divisions by differentiated cells in Drosophila (2008) (42)
- Signaling Reaches to New Dimensions in Drosophila Imaginal Discs (2000) (40)
- polyhomeotic appears to be a target of engrailed regulation in Drosophila. (1995) (38)
- The Drosophila engrailed protein is phosphorylated by a serine-specific protein kinase. (1988) (38)
- Cells must express components of the planar cell polarity system and extracellular matrix to support cytonemes (2016) (38)
- Hedgehog and its circuitous journey from producing to target cells. (2014) (37)
- Regulation of Drosophila matrix metalloprotease Mmp2 is essential for wing imaginal disc:trachea association and air sac tubulogenesis. (2009) (37)
- Deoxyribonucleic acid synthesis in cell-free extracts. 3. Catalytic properties of deoxyribonucleic acid polymerase II. (1972) (37)
- Cytoneme-mediated signaling essential for tumorigenesis (2018) (37)
- The transcription unit of the Drosophila engrailed locus: an unusually small portion of a 70,000 bp gene. (1987) (37)
- Hedgehog targets in the Drosophila embryo and the mechanisms that generate tissue-specific outputs of Hedgehog signaling (2010) (37)
- Generalizing Moving Averages for Tiling Arrays Using Combined P-Value Statistics (2010) (34)
- Paracrine signaling mediated at cell–cell contacts (2015) (34)
- Hyperactive locomotion in a Drosophila model is a functional readout for the synaptic abnormalities underlying fragile X syndrome (2017) (31)
- MYB and MYC in the cell cycle. (1991) (30)
- Modifying expression of the engrailed gene of Drosophila melanogaster. (1988) (30)
- Bicoid gradient formation and function in the Drosophila pre-syncytial blastoderm (2016) (30)
- The imperatives of context and contour for morphogen dispersion. (2012) (29)
- Functional studies of the BTB domain in the Drosophila GAGA and Mod(mdg4) proteins. (2000) (28)
- Broadly conserved roles of TMEM131 family proteins in intracellular collagen assembly and secretory cargo trafficking (2019) (28)
- Expression profiling of Drosophilaimaginal discs (2002) (28)
- fushi tarazu protein expression in the cellular blastoderm of Drosophila detected using a novel imaging technique. (1989) (27)
- Activation of the major Drosophila heat-shock genes in vitro (1981) (26)
- The contrasting roles of primary cilia and cytonemes in Hh signaling. (2014) (25)
- Spatial regulation of engrailed expression in the Drosophila embryo. (1988) (25)
- Two Patched Protein Subtypes and a Conserved Domain of Group I Proteins That Regulates Turnover* (2008) (24)
- Smoothened Regulates Activator and Repressor Functions of Hedgehog Signaling via Two Distinct Mechanisms* (2006) (24)
- DaXi—high-resolution, large imaging volume and multi-view single-objective light-sheet microscopy (2022) (23)
- The phenotype of engrailed mutations in the antenna of Drosophila. (1983) (23)
- A Screen for Modifiers of Hedgehog Signaling in Drosophila melanogaster Identifies swm and mts (2008) (22)
- Analysis of DNA Polymerases II and III in Mutants of Escherichia coli (22)
- 4. Bacterial DNA Polymerases (1974) (21)
- Development of the D. melanogaster caudal segments involves suppression of the ventral regions of A8, A9 and A10. (1992) (21)
- Barcoding Hedgehog for Intracellular Transport (2011) (21)
- Analysis of the genes involved in organizing the tail segments of the Drosophila melanogaster embryo (1995) (21)
- A gene related to the proto-oncogene fps/fes is expressed at diverse times during the life cycle of Drosophila melanogaster (1991) (18)
- Expression during Drosophila development of DER, a gene related to erbB-1 and neu: correlations with mutant phenotypes. (1991) (18)
- Pictures in cell biology. Cytonemes. (1999) (18)
- A Novel Interaction Between hedgehog and Notch Promotes Proliferation at the Anterior–Posterior Organizer of the Drosophila Wing (2011) (17)
- The conserved transmembrane protein TMEM-39 coordinates with COPII to promote collagen secretion and regulate ER stress response (2021) (17)
- Proto-oncogenes of Drosophila melanogaster. (1985) (17)
- Microarray Comparison of Anterior and Posterior Drosophila Wing Imaginal Disc Cells Identifies Novel Wing Genes (2013) (17)
- Selection and characterization of sequences with high affinity for the engrailed protein of Drosophila (1995) (15)
- Allele-specific quantification of Drosophila engrailed and invected transcripts. (1994) (15)
- Diverse expression of dsrc29A, a gene related to src, during the life cycle of Drosophila melanogaster. (1990) (13)
- Developmental compartments in the larval trachea of Drosophila (2015) (12)
- The Chromatin-Remodeling Protein Osa Interacts With CyclinE in Drosophila Eye Imaginal Discs (2010) (12)
- Direct Delivery Mechanisms of Morphogen Dispersion (2011) (12)
- Visualizing Dynamics of Cell Signaling In Vivo with a Phase Separation-Based Kinase Reporter. (2018) (12)
- Cytonemes extend their reach (2013) (11)
- A Path to Pattern. (2016) (11)
- Association of the Drosophila melanogaster engrailed protein with specific soluble nuclear protein complexes. (1988) (10)
- Transcription of the major Drosophila heat-shock genes in vitro. (1981) (10)
- Cytonemes with complex geometries and composition extend into invaginations of target cells (2020) (8)
- Structure and expression of two classes of mammalian homeo-box-containing genes. (1985) (7)
- SPECTROPHOTOMETRIC STUDIES ON THE DECARBOXYLATION OF &KETO ACIDS* (2003) (6)
- Regulated delivery controls Drosophila Hedgehog, Wingless and Decapentaplegic signaling (2020) (5)
- Scripting a place in time. (2017) (5)
- Linear RNA amplification for the production of microarray hybridization probes. (2008) (5)
- [3] Deoxyribonucleic acid polymerase III (Escherichia coli K12) (1974) (5)
- Hedgehog produced by the Drosophila wing imaginal disc induces distinct responses in three target tissues (2020) (4)
- Developmental biology: Nanotubes in the niche (2015) (4)
- Hedgehog produced by the drosophila wing imaginal disc induces distinct responses in three target tissues. (2020) (4)
- Deoxyribonucleic acid polymerase 3 (Escherichia coli K12). (1974) (3)
- Protocol for ex vivo time lapse imaging of Drosophila melanogaster cytonemes (2022) (3)
- Expression and Characterization of Drosophila Signal Peptide Peptidase-Like (sppL), a Gene That Encodes an Intramembrane Protease (2012) (3)
- Author response: Cells must express components of the planar cell polarity system and extracellular matrix to support cytonemes (2016) (2)
- Macrophages Help Cells Connect to Pattern Zebrafish Stripes. (2017) (2)
- Withdrawal: Dm1-MMP, a matrix metalloproteinase from Drosophila with a potential role in extracellular matrix remodeling during neural development. (2019) (2)
- Elimination of nurse cell nuclei that shuttle into oocytes during oogenesis (2021) (2)
- Another arrow in the Drosophila quiver (2002) (2)
- Regulated delivery controls Drosophila Hedgehog, Wingless, and Decapentaplegic signaling (2021) (2)
- Studies on DNA Polymerases II and III of Escherichia coli (1973) (2)
- Correction: Bicoid gradient formation and function in the Drosophila pre-syncytial blastoderm (2017) (2)
- Insights & Perspectives Paracrine signaling mediated at cellcell contacts (2014) (1)
- Escherichia coli DNA Polymerases II and III (1974) (1)
- Hedgehog produced by the Drosophila wing imaginal disc induces distinct expression responses in three target tissues (2020) (1)
- DR-78, a novel Drosophila melanogaster genomic DNA fragment highly homologous to the DNA-binding domain of thyroid hormone-retinoic acid-vitamin D receptor subfamily. (1993) (1)
- Metabolic control of progenitor cell propagation during Drosophila tracheal remodeling (2022) (1)
- Instructions to author (1971) (1)
- The engrailed locus of Drosophila melanogaster: genetic, developmental, and molecular studies. (1985) (1)
- Fusion of Drosophila oocytes with specified germline sister cells (2020) (1)
- A novel interaction between hedgehog and Notch promotes proliferation at the AP organizer of the Drosophila wing imaginal disc (2010) (0)
- Editorial Board (2002) (0)
- Author ' s personal copy Regulation of Drosophila matrix metalloprotease Mmp 2 is essential for wing imaginal disc : trachea association and air sac tubulogenesis (2012) (0)
- Author response: Regulated delivery controls Drosophila Hedgehog, Wingless, and Decapentaplegic signaling (2021) (0)
- Title Augmented noncanonical BMP type II receptor signaling mediates the synaptic abnormality of fragile X syndrome (2016) (0)
- Editorial Board (2002) (0)
- Instructions to authors (2004) (0)
- Results Sequential expression of engrailed stripes in the grasshopper embryo (2005) (0)
- Editorial Board (2002) (0)
- Analysis ofDNA Polymerases IIandIIIinMutants ofEscherichia coli Thermosensitive forDNA Synthesis (polAl mutants/phosphocellulose chromatography/dnaE locus) (1971) (0)
- Editorial Board (2005) (0)
- Instructions to authors (2004) (0)
- Instructions to Authors (2004) (0)
- Editorial Board (2003) (0)
- The conserved ER-transmembrane protein TMEM39 coordinates with COPII to promote collagen secretion and prevent ER stress (2020) (0)
- A cells respond in part by expressing the Dpp gene in a narrow stripe of cells on the anterior side of the A / P border ( Figure 1 A (1999) (0)
- Instructions to authors (2002) (0)
- 20 – engrailed, A Gene for All Segments (1991) (0)
- Instructions to Authors (2003) (0)
- Author response: Developmental compartments in the larval trachea of Drosophila (2015) (0)
- Instructions to authors (2002) (0)
- Summary Development of the D . melanogaster caudal segments involves suppression of the ventral regions of A 8 , A 9 and A 10 (1999) (0)
- Editorial Board (2004) (0)
- portions of the Drosophila engrailed promoter. Region-specific recombination and expression are directed by (0)
- Preface. (2022) (0)
- NF-kBActivation Upregulates PKM2 Expression and Promotes Tumorigenesis (2018) (0)
- Instructions to authors (2003) (0)
- Author response: Bicoid gradient formation and function in the Drosophila pre-syncytial blastoderm (2016) (0)
- STUDIES OF THE ENGRAILED HOMEODOMAIN AND OF AN ENGRAILED HOMEODOMAWDNA COMPLEX (2003) (0)
- Instructions to Authors (2004) (0)
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