Thomas C. Südhof
#2,901
Most Influential Person
German biochemist
Why Is Thomas C. Südhof Influential?
(Suggest an Edit or Addition)According to Wikipedia, Thomas Christian Südhof , ForMemRS, is a German-American biochemist known for his study of synaptic transmission. Currently, he is a professor in the School of Medicine in the Department of Molecular and Cellular Physiology, and by courtesy in Neurology, and in Psychiatry and Behavioral Sciences at Stanford University.
Thomas C. Südhof's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Papers
- Direct conversion of fibroblasts to functional neurons by defined factors (2010) (2706)
- The synaptic vesicle cycle: a cascade of proteinprotein interactions (1995) (1979)
- Membrane Fusion: Grappling with SNARE and SM Proteins (2009) (1773)
- Neuroligins and neurexins link synaptic function to cognitive disease (2008) (1539)
- Synaptotagmin I: A major Ca2+ sensor for transmitter release at a central synapse (1994) (1420)
- The synaptic vesicle cycle (2004) (1374)
- Membrane Fusion (2003) (1329)
- α-Synuclein Promotes SNARE-Complex Assembly in Vivo and in Vitro (2010) (1312)
- Synaptic assembly of the brain in the absence of neurotransmitter secretion. (2000) (1273)
- Membrane fusion and exocytosis. (1999) (1196)
- Botulinum neurotoxin A selectively cleaves the synaptic protein SNAP-25 (1993) (1131)
- Induction of human neuronal cells by defined transcription factors (2011) (1119)
- A Transcriptively Active Complex of APP with Fe65 and Histone Acetyltransferase Tip60 (2001) (1102)
- The synaptic vesicle cycle. (2004) (1088)
- Synaptotagmin I functions as a calcium regulator of release probability (2001) (922)
- Synaptotagmin: a calcium sensor on the synaptic vesicle surface. (1992) (906)
- A Neuroligin-3 Mutation Implicated in Autism Increases Inhibitory Synaptic Transmission in Mice (2007) (880)
- Rapid Single-Step Induction of Functional Neurons from Human Pluripotent Stem Cells (2013) (865)
- Neurotransmitter Release: The Last Millisecond in the Life of a Synaptic Vesicle (2013) (821)
- α-Synuclein Cooperates with CSPα in Preventing Neurodegeneration (2005) (818)
- Phospholipid binding by a synaptic vesicle protein homologous to the regulatory region of protein kinase C (1990) (794)
- The Presynaptic Active Zone (2012) (783)
- Synaptic vesicle membrane fusion complex: action of clostridial neurotoxins on assembly. (1994) (778)
- C2-domains, Structure and Function of a Universal Ca2+-binding Domain* (1998) (774)
- SynCAM, a Synaptic Adhesion Molecule That Drives Synapse Assembly (2002) (770)
- Neuroligins Determine Synapse Maturation and Function (2006) (756)
- The LDL receptor gene: a mosaic of exons shared with different proteins. (1985) (749)
- A conformational switch in syntaxin during exocytosis: role of munc18 (1999) (727)
- Synaptic vesicle fusion complex contains unc-18 homologue bound to syntaxin (1993) (721)
- Binding of neuroligins to PSD-95. (1997) (709)
- Munc13-1 is essential for fusion competence of glutamatergic synaptic vesicles (1999) (698)
- Essential functions of synapsins I and II in synaptic vesicle regulation (1995) (695)
- Rim is a putative Rab3 effector in regulating synaptic-vesicle fusion (1997) (676)
- Structure of the first C2 domain of synaptotagmin I: A novel Ca2+/phospholipid-binding fold (1995) (661)
- Neurexins: synaptic cell surface proteins related to the alpha-latrotoxin receptor and laminin. (1992) (654)
- Neuroligin 1 is a postsynaptic cell-adhesion molecule of excitatory synapses. (1999) (652)
- SNARE Function Analyzed in Synaptobrevin/VAMP Knockout Mice (2001) (629)
- Ca2+-dependent and -independent activities of neural and non-neural synaptotagmins (1995) (614)
- RIM1α forms a protein scaffold for regulating neurotransmitter release at the active zone (2002) (610)
- Snares and munc18 in synaptic vesicle fusion (2002) (564)
- A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60. (2001) (547)
- α-Neurexins couple Ca2+ channels to synaptic vesicle exocytosis (2003) (545)
- Activity-Dependent Validation of Excitatory versus Inhibitory Synapses by Neuroligin-1 versus Neuroligin-2 (2007) (535)
- Alpha-synuclein cooperates with CSPalpha in preventing neurodegeneration. (2005) (534)
- A Tripartite Protein Complex with the Potential to Couple Synaptic Vesicle Exocytosis to Cell Adhesion in Brain (1998) (527)
- Common circuit defect of excitatory-inhibitory balance in mouse models of autism (2009) (517)
- Proteins of synaptic vesicles involved in exocytosis and membrane recycling (1991) (508)
- RIM Proteins Tether Ca2+ Channels to Presynaptic Active Zones via a Direct PDZ-Domain Interaction (2011) (506)
- Parkinson-like syndrome induced by continuous MPTP infusion: convergent roles of the ubiquitin-proteasome system and alpha-synuclein. (2005) (504)
- RIBEYE, a Component of Synaptic Ribbons A Protein's Journey through Evolution Provides Insight into Synaptic Ribbon Function (2000) (502)
- Synaptotagmins: Why So Many?* (2002) (490)
- Putative receptor for inositol 1,4,5-trisphosphate similar to ryanodine receptor (1989) (488)
- Cellubrevin is a ubiquitous tetanus-toxin substrate homologous to a putative synaptic vesicle fusion protein (1993) (483)
- Synaptotagmin I is a high affinity receptor for clathrin AP-2: Implications for membrane recycling (1994) (482)
- A Neural Circuit for Memory Specificity and Generalization (2013) (482)
- Hierarchical Mechanisms for Direct Reprogramming of Fibroblasts to Neurons (2013) (472)
- β Phorbol Ester- and Diacylglycerol-Induced Augmentation of Transmitter Release Is Mediated by Munc13s and Not by PKCs (2002) (468)
- Synapsins: mosaics of shared and individual domains in a family of synaptic vesicle phosphoproteins. (1989) (466)
- Complexins: Cytosolic proteins that regulate SNAP receptor function (1995) (464)
- The role of Rab3A in neurotransmitter release (1994) (460)
- Complexins Regulate a Late Step in Ca2+-Dependent Neurotransmitter Release (2001) (447)
- Synaptotagmins: C2-Domain Proteins That Regulate Membrane Traffic (1996) (444)
- A Complexin/Synaptotagmin 1 Switch Controls Fast Synaptic Vesicle Exocytosis (2006) (442)
- A single C2 domain from synaptotagmin I is sufficient for high affinity Ca2+/phospholipid binding. (1993) (439)
- Structures, Alternative Splicing, and Neurexin Binding of Multiple Neuroligins (*) (1996) (433)
- Postsynaptic membrane fusion and long-term potentiation. (1998) (430)
- Direct conversion of mouse fibroblasts to self-renewing, tripotent neural precursor cells (2012) (425)
- Cartography of neurexins: More than 1000 isoforms generated by alternative splicing and expressed in distinct subsets of neurons (1995) (425)
- rab3 is a small GTP-binding protein exclusively localized to synaptic vesicles. (1990) (421)
- Proteolysis of SNAP-25 by types E and A botulinal neurotoxins. (1994) (416)
- A stoichiometric complex of neurexins and dystroglycan in brain (2001) (413)
- Munc13-1 Is a Presynaptic Phorbol Ester Receptor that Enhances Neurotransmitter Release (1998) (410)
- Nicastrin Functions as a γ-Secretase-Substrate Receptor (2005) (409)
- The small GTP-binding protein Rab3A regulates a late step in synaptic vesicle fusion (1997) (409)
- Three-Dimensional Structure of the Complexin/SNARE Complex (2002) (407)
- Neuroligin 1: A splice site-specific ligand for β-neurexins (1995) (405)
- Synaptic Neurexin Complexes: A Molecular Code for the Logic of Neural Circuits (2017) (404)
- Munc18-1 Promotes Large Dense-Core Vesicle Docking (2001) (401)
- A small GTP-binding protein dissociates from synaptic vesicles during exocytosis (1991) (399)
- Mutation in LDL receptor: Alu-Alu recombination deletes exons encoding transmembrane and cytoplasmic domains. (1985) (397)
- A Splice Code for trans-Synaptic Cell Adhesion Mediated by Binding of Neuroligin 1 to α- and β-Neurexins (2005) (394)
- Mouse neurexin-1α deletion causes correlated electrophysiological and behavioral changes consistent with cognitive impairments (2009) (390)
- Neuroligin-1 Deletion Results in Impaired Spatial Memory and Increased Repetitive Behavior (2010) (389)
- A Broken α-Helix in Folded α-Synuclein* (2003) (388)
- Acid-dependent ligand dissociation and recycling of LDL receptor mediated by growth factor homology region (1987) (384)
- Structure and expression of the rat inositol 1,4,5-trisphosphate receptor. (1990) (383)
- Double-knockout mice for alpha- and beta-synucleins: effect on synaptic functions. (2004) (380)
- Mammalian Homologues of Caenorhabditis elegans unc-13 Gene Define Novel Family of C2-domain Proteins (*) (1995) (377)
- Three-Dimensional Structure of the Synaptotagmin 1 C2B-Domain Synaptotagmin 1 as a Phospholipid Binding Machine (2001) (372)
- Neurexins: three genes and 1001 products. (1998) (365)
- The membrane fusion enigma: SNAREs, Sec1/Munc18 proteins, and their accomplices--guilty as charged? (2012) (364)
- Synaptic vesicles and exocytosis. (1994) (361)
- A dual-Ca2+-sensor model for neurotransmitter release in a central synapse (2007) (348)
- Munc18-1 binds directly to the neuronal SNARE complex (2007) (342)
- Autism-Associated Neuroligin-3 Mutations Commonly Impair Striatal Circuits to Boost Repetitive Behaviors (2014) (341)
- RIM Determines Ca2+ Channel Density and Vesicle Docking at the Presynaptic Active Zone (2011) (338)
- Mevinolin, an inhibitor of cholesterol synthesis, induces mRNA for low density lipoprotein receptor in livers of hamsters and rabbits. (1986) (337)
- α-Synuclein assembles into higher-order multimers upon membrane binding to promote SNARE complex formation (2014) (332)
- Complexin Controls the Force Transfer from SNARE Complexes to Membranes in Fusion (2009) (331)
- SV2A and SV2B Function as Redundant Ca2+ Regulators in Neurotransmitter Release (1999) (330)
- Direct lineage conversion of terminally differentiated hepatocytes to functional neurons. (2011) (329)
- Synapses and Alzheimer's disease. (2012) (328)
- Structure of a novel InsP3 receptor. (1991) (327)
- Neuroligin 1: a splice site-specific ligand for beta-neurexins. (1995) (325)
- Exo-endocytotic recycling of synaptic vesicles in developing processes of cultured hippocampal neurons (1992) (324)
- Calcium control of neurotransmitter release. (2012) (323)
- Cell biology of Ca2+-triggered exocytosis. (2010) (323)
- Domain structure of synaptotagmin (p65) (1991) (322)
- LRRTM2 Functions as a Neurexin Ligand in Promoting Excitatory Synapse Formation (2009) (320)
- Dissection of Amyloid-β Precursor Protein-dependent Transcriptional Transactivation* (2004) (319)
- Association of Neuronal Calcium Channels with Modular Adaptor Proteins* (1999) (319)
- Three-Dimensional Structure of an Evolutionarily Conserved N-Terminal Domain of Syntaxin 1A (1998) (319)
- Membrane fusion machinery: Insights from synaptic proteins (1993) (317)
- Short-term synaptic plasticity is altered in mice lacking synapsin I (1993) (312)
- The ligand binding site and transduction mechanism in the inositol‐1,4,5‐triphosphate receptor. (1990) (302)
- Essential Roles in Synaptic Plasticity for Synaptogyrin I and Synaptophysin I (1999) (301)
- ApoE2, ApoE3, and ApoE4 Differentially Stimulate APP Transcription and Aβ Secretion (2017) (301)
- A Novel Multiple PDZ Domain-containing Molecule Interacting withN-Methyl-d-aspartateReceptors and Neuronal Cell Adhesion Proteins* (1998) (300)
- Tetanus toxin action: inhibition of neurotransmitter release linked to synaptobrevin proteolysis. (1992) (299)
- Towards an Understanding of Synapse Formation (2018) (298)
- Bipartite Ca2+-Binding Motif in C2 Domains of Synaptotagmin and Protein Kinase C (1996) (297)
- A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis (2012) (295)
- Synaptotagmin-1, -2, and -9: Ca2+ Sensors for Fast Release that Specify Distinct Presynaptic Properties in Subsets of Neurons (2007) (293)
- Rab geranylgeranyl transferase. A multisubunit enzyme that prenylates GTP-binding proteins terminating in Cys-X-Cys or Cys-Cys. (1992) (287)
- Ca2+ binding to synaptotagmin: how many Ca2+ ions bind to the tip of a C2‐domain? (1998) (286)
- Generation of Induced Neuronal Cells by the Single Reprogramming Factor ASCL1 (2014) (284)
- Purification of component A of Rab geranylgeranyl transferase: Possible identity with the choroideremia gene product (1992) (283)
- Colocalization of synaptophysin with transferrin receptors: implications for synaptic vesicle biogenesis (1991) (282)
- A synaptic vesicle protein with a novel cytoplasmic domain and four transmembrane regions. (1987) (282)
- Cellular Taxonomy of the Mouse Striatum as Revealed by Single-Cell RNA-Seq. (2016) (280)
- Conformational Switch of Syntaxin-1 Controls Synaptic Vesicle Fusion (2008) (279)
- Autism-linked neuroligin-3 R451C mutation differentially alters hippocampal and cortical synaptic function (2011) (278)
- RAB3 and synaptotagmin: the yin and yang of synaptic membrane fusion. (1998) (277)
- Synaptic vesicle exocytosis. (2011) (274)
- A Complete Genetic Analysis of Neuronal Rab3 Function (2004) (273)
- Phosphorylation of Munc-18/n-Sec1/rbSec1 by Protein Kinase C (1996) (272)
- Structure and evolution of neurexin genes: insight into the mechanism of alternative splicing. (2002) (269)
- Co-expression in vertebrate tissues and cell lines of multiple inositol 1,4,5-trisphosphate (InsP3) receptors with distinct affinities for InsP3. (1994) (268)
- Presenilins are Essential for Regulating Neurotransmitter Release (2009) (265)
- Synaptotagmins form a hierarchy of exocytotic Ca2+ sensors with distinct Ca2+ affinities (2002) (261)
- A Munc13/RIM/Rab3 tripartite complex: from priming to plasticity? (2005) (256)
- Cleavage of members of the synaptobrevin/VAMP family by types D and F botulinal neurotoxins and tetanus toxin. (1994) (255)
- Ryanodine and inositol trisphosphate receptors coexist in avian cerebellar Purkinje neurons (1991) (254)
- A synaptic vesicle membrane protein is conserved from mammals to Drosophila (1989) (253)
- RIM Proteins Activate Vesicle Priming by Reversing Autoinhibitory Homodimerization of Munc13 (2011) (253)
- RIM1α is required for presynaptic long-term potentiation (2002) (253)
- The Morphological and Molecular Nature of Synaptic Vesicle Priming at Presynaptic Active Zones (2014) (252)
- Synaptophysin, a major synaptic vesicle protein, is not essential for neurotransmitter release. (1996) (252)
- A Phospho-Switch Controls the Dynamic Association of Synapsins with Synaptic Vesicles (1999) (252)
- Close membrane-membrane proximity induced by Ca2+-dependent multivalent binding of synaptotagmin-1 to phospholipids (2006) (250)
- Dynamin GTPase regulated by protein kinase C phosphorylation in nerve terminals (1993) (249)
- Synaptotagmin-1 functions as the Ca2+-sensor for spontaneous release (2009) (248)
- A family of RIM-binding proteins regulated by alternative splicing: Implications for the genesis of synaptic active zones (2002) (247)
- CASK Functions as a Mg2+-Independent Neurexin Kinase (2008) (247)
- The Synaptic VesicleCycle Revisited (2000) (245)
- Native α-synuclein induces clustering of synaptic-vesicle mimics via binding to phospholipids and synaptobrevin-2/VAMP2 (2013) (243)
- Properties of native brain α-synuclein (2013) (240)
- Synaptobrevin is essential for fast synaptic-vesicle endocytosis (2004) (240)
- Binding of synaptotagmin to the α-latrotoxin receptor implicates both in synaptic vesicle exocytosis (1991) (238)
- Cartography of neurexin alternative splicing mapped by single-molecule long-read mRNA sequencing (2014) (236)
- A splice code for trans-synaptic cell adhesion mediated by binding of neuroligin 1 to alpha- and beta-neurexins. (2005) (235)
- Sterol-dependent repression of low density lipoprotein receptor promoter mediated by 16-base pair sequence adjacent to binding site for transcription factor Sp1. (1988) (233)
- Architecture of the Synaptotagmin-SNARE Machinery for Neuronal Exocytosis (2015) (232)
- Autonomous Function of Synaptotagmin 1 in Triggering Synchronous Release Independent of Asynchronous Release (2005) (232)
- SynGO: An Evidence-Based, Expert-Curated Knowledge Base for the Synapse (2019) (231)
- Synaptotagmin-1 and Synaptotagmin-7 Trigger Synchronous and Asynchronous Phases of Neurotransmitter Release (2013) (231)
- Endocannabinoid-Mediated Long-Term Plasticity Requires cAMP/PKA Signaling and RIM1α (2007) (230)
- The Synaptic Vesicle Protein CSPα Prevents Presynaptic Degeneration (2004) (227)
- Phosphorylation of RIM1α by PKA Triggers Presynaptic Long-Term Potentiation at Cerebellar Parallel Fiber Synapses (2003) (227)
- Synaptotagmin VII as a Plasma Membrane Ca2+ Sensor in Exocytosis (2001) (226)
- The RIM/NIM Family of Neuronal C2 Domain Proteins (2000) (225)
- Structural and functional conservation of synaptotagmin (p65) in Drosophila and humans. (1991) (225)
- Synaptotagmin–Syntaxin Interaction: The C2 Domain as a Ca2+-Dependent Electrostatic Switch (1997) (224)
- Autism-Associated Neuroligin-3 Mutations Commonly Disrupt Tonic Endocannabinoid Signaling (2013) (224)
- Autism-associated SHANK3 haploinsufficiency causes Ih channelopathy in human neurons (2016) (224)
- Binding Properties of Neuroligin 1 and Neurexin 1β Reveal Function as Heterophilic Cell Adhesion Molecules* (1997) (223)
- Presynaptic Neurexin-3 Alternative Splicing trans-Synaptically Controls Postsynaptic AMPA Receptor Trafficking (2013) (222)
- Nicastrin functions as a gamma-secretase-substrate receptor. (2005) (219)
- v‐SNAREs control exocytosis of vesicles from priming to fusion (2005) (219)
- Association of Rab3A with synaptic vesicles at late stages of the secretory pathway (1991) (218)
- Solution structures of the Ca2+-free and Ca2+-bound C2A domain of synaptotagmin I: does Ca2+ induce a conformational change? (1998) (215)
- Sly1 binds to Golgi and ER syntaxins via a conserved N-terminal peptide motif. (2002) (213)
- Synaptotagmin II. A novel differentially distributed form of synaptotagmin. (1991) (210)
- Mints, Munc18-interacting Proteins in Synaptic Vesicle Exocytosis* (1997) (210)
- CSPα promotes SNARE-complex assembly by chaperoning SNAP-25 during synaptic activity (2011) (210)
- Cleavage of Amyloid-β Precursor Protein and Amyloid-β Precursor-like Protein by BACE 1* (2004) (209)
- Synaptic cell adhesion. (2012) (206)
- Selective Capability of SynCAM and Neuroligin for Functional Synapse Assembly (2005) (206)
- Intracellular calcium dependence of large dense-core vesicle exocytosis in the absence of synaptotagmin I (2001) (204)
- Cell Biology and Pathophysiology of α-Synuclein. (2018) (202)
- Functional properties of multiple synaptotagmins in brain (1994) (202)
- A Trimeric Protein Complex Functions as a Synaptic Chaperone Machine (2001) (201)
- Synaptotagmin-2 Is Essential for Survival and Contributes to Ca2+ Triggering of Neurotransmitter Release in Central and Neuromuscular Synapses (2006) (201)
- SV2C is a synaptic vesicle protein with an unusually restricted localization: anatomy of a synaptic vesicle protein family (1999) (199)
- How Tlg2p/syntaxin 16 'snares’ Vps45 (2002) (198)
- alpha-Latrotoxin and its receptors: neurexins and CIRL/latrophilins. (2001) (196)
- Rab proteins in regulated exocytosis. (1994) (194)
- C 2-domains , Structure and Function of a Universal Ca 2 1-binding Domain * (1998) (194)
- Generation of pure GABAergic neurons by transcription factor programming (2017) (192)
- Synaptotagmin-1 and -7 are functionally overlapping Ca2+ sensors for exocytosis in adrenal chromaffin cells (2008) (192)
- Deletion of CASK in mice is lethal and impairs synaptic function (2007) (192)
- Impaired learning in mice with abnormal short-lived plasticity (1996) (189)
- Synaptic targeting of rabphilin-3A, a synaptic vesicle Ca2+/phospholipid-binding protein, depends on rab3A/3C (1994) (188)
- Genetics of synaptic vesicle function: toward the complete functional anatomy of an organelle. (1999) (187)
- Binding of F-spondin to amyloid-β precursor protein: A candidate amyloid-β precursor protein ligand that modulates amyloid-β precursor protein cleavage (2004) (187)
- Increased anxiety‐like behavior in mice lacking the inhibitory synapse cell adhesion molecule neuroligin 2 (2009) (185)
- Differential expression and regulation of multiple dynamins. (1994) (185)
- Structures of Neuroligin-1 and the Neuroligin-1/Neurexin-1β Complex Reveal Specific Protein-Protein and Protein-Ca2+ Interactions (2007) (185)
- A Novel Ubiquitous Form of Munc-18 Interacts with Multiple Syntaxins. (1995) (185)
- LTP Requires a Unique Postsynaptic SNARE Fusion Machinery (2013) (184)
- Mints as Adaptors (2000) (184)
- The Appendage Domain of α-Adaptin Is a High Affinity Binding Site for Dynamin (*) (1995) (182)
- The synaptic vesicle cycle revisited. (2000) (182)
- Synaptic Core Complex of Synaptobrevin, Syntaxin, and SNAP25 Forms High Affinity -SNAP Binding Site (*) (1995) (182)
- Induced neuronal cells: how to make and define a neuron. (2011) (182)
- Munc13 C2B-Domain – an Activity-Dependent Ca2+-Regulator of Synaptic Exocytosis (2010) (181)
- Mechanism of phospholipid binding by the C2A-domain of synaptotagmin I. (1998) (181)
- Propagation of prions causing synucleinopathies in cultured cells (2015) (178)
- gCap39, a calcium ion- and polyphosphoinositide-regulated actin capping protein. (1990) (178)
- 42 bp element from LDL receptor gene confers end-product repression by sterols when inserted into viral TK promoter (1987) (176)
- Genetic analysis of synaptotagmin 2 in spontaneous and Ca2+‐triggered neurotransmitter release (2006) (176)
- Piccolo and bassoon maintain synaptic vesicle clustering without directly participating in vesicle exocytosis (2010) (175)
- Molecular determinants of regulated exocytosis. (2002) (174)
- alpha-Latrotoxin receptor CIRL/latrophilin 1 (CL1) defines an unusual family of ubiquitous G-protein-linked receptors. G-protein coupling not required for triggering exocytosis. (1998) (173)
- DOC2 Proteins in Rat Brain: Complementary Distribution and Proposed Function as Vesicular Adapter Proteins in Early Stages of Secretion (1997) (172)
- Impaired insulin secretion and glucose intolerance in synaptotagmin-7 null mutant mice (2008) (171)
- Candidate autism gene screen identifies critical role for cell-adhesion molecule CASPR2 in dendritic arborization and spine development (2012) (171)
- Multiple Roles for the Active Zone Protein RIM1α in Late Stages of Neurotransmitter Release (2004) (170)
- A Role for cAMP in Long-Term Depression at Hippocampal Mossy Fiber Synapses (1998) (169)
- A Neuroligin-4 Missense Mutation Associated with Autism Impairs Neuroligin-4 Folding and Endoplasmic Reticulum Export (2009) (168)
- RIM1alpha is required for presynaptic long-term potentiation. (2002) (168)
- A molecular machine for neurotransmitter release: synaptotagmin and beyond (2013) (168)
- E-Syts, a family of membranous Ca2+-sensor proteins with multiple C2 domains (2007) (166)
- Rabphilin Knock-Out Mice Reveal That Rabphilin Is Not Required for Rab3 Function in Regulating Neurotransmitter Release (1999) (165)
- Selective Interaction of Complexin with the Neuronal SNARE Complex (2000) (163)
- The primed SNARE–complexin–synaptotagmin complex for neuronal exocytosis (2017) (163)
- Munc18-1 binding to the neuronal SNARE complex controls synaptic vesicle priming (2009) (163)
- cAMP oscillations and retinal activity are permissive for ephrin signaling during the establishment of the retinotopic map (2007) (163)
- EHSH1/Intersectin, a Protein That Contains EH and SH3 Domains and Binds to Dynamin and SNAP-25 (1999) (162)
- CASK and Protein 4.1 Support F-actin Nucleation on Neurexins* (2001) (161)
- Localization Versus Function of Rab3 Proteins (2002) (161)
- Interaction of synaptotagmin with the cytoplasmic domains of neurexins (1993) (161)
- Rab3 Superprimes Synaptic Vesicles for Release: Implications for Short-Term Synaptic Plasticity (2006) (161)
- Dissection of Synapse Induction by Neuroligins (2005) (160)
- The Making of Neurexins (1998) (159)
- A Novel Family of Phosphatidylinositol 4-Kinases Conserved from Yeast to Humans* (2001) (158)
- Neuroligin-2 Deletion Selectively Decreases Inhibitory Synaptic Transmission Originating from Fast-Spiking but Not from Somatostatin-Positive Interneurons (2009) (156)
- Distinct Neuronal Coding Schemes in Memory Revealed by Selective Erasure of Fast Synchronous Synaptic Transmission (2012) (154)
- Cassette of eight exons shared by genes for LDL receptor and EGF precursor. (1985) (154)
- Comprehensive qPCR profiling of gene expression in single neuronal cells (2012) (153)
- The synaptic vesicle protein CSP alpha prevents presynaptic degeneration. (2004) (152)
- Human Neuropsychiatric Disease Modeling using Conditional Deletion Reveals Synaptic Transmission Defects Caused by Heterozygous Mutations in NRXN1. (2015) (151)
- Dual Modes of Munc18-1/SNARE Interactions Are Coupled by Functionally Critical Binding to Syntaxin-1 N Terminus (2007) (151)
- Vam3p structure reveals conserved and divergent properties of syntaxins (2001) (151)
- Three direct repeats and a TATA-like sequence are required for regulated expression of the human low density lipoprotein receptor gene. (1987) (150)
- Conserved domain structure of beta-neurexins. Unusual cleaved signal sequences in receptor-like neuronal cell-surface proteins. (1994) (149)
- Structural Determinants of Synaptobrevin 2 Function in Synaptic Vesicle Fusion (2006) (148)
- Neurexins Physically and Functionally Interact with GABAA Receptors (2010) (148)
- Complexin Clamps Asynchronous Release by Blocking a Secondary Ca2+ Sensor via Its Accessory α Helix (2010) (148)
- SV2 Renders Primed Synaptic Vesicles Competent for Ca2+-Induced Exocytosis (2009) (147)
- Rab3C is a synaptic vesicle protein that dissociates from synaptic vesicles after stimulation of exocytosis. (1994) (146)
- High Affinity Neurexin Binding to Cell Adhesion G-protein-coupled Receptor CIRL1/Latrophilin-1 Produces an Intercellular Adhesion Complex* (2012) (144)
- SynCAM 1 Adhesion Dynamically Regulates Synapse Number and Impacts Plasticity and Learning (2010) (143)
- Augmenting neurotransmitter release by enhancing the apparent Ca2+ affinity of synaptotagmin 1. (2005) (142)
- Membrane fusion. (2003) (141)
- Rab3 reversibly recruits rabphilin to synaptic vesicles by a mechanism analogous to raf recruitment by ras. (1996) (140)
- The Evolutionary Pressure to Inactivate (1997) (140)
- Integrative genomic and functional analyses reveal neuronal subtype differentiation bias in human embryonic stem cell lines (2007) (140)
- Myt1l safeguards neuronal identity by actively repressing many non-neuronal fates (2017) (139)
- Definition of a Molecular Pathway Mediating α-Synuclein Neurotoxicity (2015) (139)
- Histogenesis and differentiation potential of central neurocytomas. (1991) (139)
- Synaptophysin is targeted to similar microvesicles in CHO and PC12 cells. (1989) (138)
- The Presynaptic Active Zone Protein RIM1α Is Critical for Normal Learning and Memory (2004) (138)
- Distinct Ca2+ and Sr2+ Binding Properties of Synaptotagmins (1995) (137)
- Isolation of mammalian calelectrins: a new class of ubiquitous Ca2+-regulated proteins. (1984) (137)
- The cell-adhesion G protein-coupled receptor BAI3 is a high-affinity receptor for C1q-like proteins (2011) (136)
- Inositol 1,4,5-Trisphosphate receptor causes formation of ER cisternal stacks in transfected fibroblasts and in cerebellar purkinje cells (1994) (136)
- Latrophilins Function as Heterophilic Cell-adhesion Molecules by Binding to Teneurins (2013) (136)
- Cell biology of Ca 2+ -triggered exocytosis (2010) (135)
- Transmembrane topography and evolutionary conservation of synaptophysin. (1989) (135)
- Systematic Mutagenesis of α-Synuclein Reveals Distinct Sequence Requirements for Physiological and Pathological Activities (2012) (135)
- CSPα knockout causes neurodegeneration by impairing SNAP‐25 function (2012) (134)
- Doc2 Supports Spontaneous Synaptic Transmission by a Ca2+-Independent Mechanism (2011) (134)
- Climate change and the integrity of science. (2010) (132)
- Extracellular Domains of α-Neurexins Participate in Regulating Synaptic Transmission by Selectively Affecting N- and P/Q-Type Ca2+ Channels (2005) (131)
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- Latrophilin GPCRs direct synapse specificity by coincident binding of FLRTs and teneurins (2019) (112)
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- Phosphatidylinositol Phosphates as Co-activators of Ca2+ Binding to C2 Domains of Synaptotagmin 1* (2006) (111)
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- Structure of the 116-kDa polypeptide of the clathrin-coated vesicle/synaptic vesicle proton pump. (1991) (109)
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- Dynamic Binding Mode of a Synaptotagmin-1-SNARE Complex in Solution (2015) (108)
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- Synaptotagmin-12, a synaptic vesicle phosphoprotein that modulates spontaneous neurotransmitter release (2007) (106)
- Rabphilin regulates SNARE‐dependent re‐priming of synaptic vesicles for fusion (2006) (106)
- Calmodulin Controls Synaptic Strength via Presynaptic Activation of Calmodulin Kinase II (2010) (105)
- Regulation of APP-Dependent Transcription Complexes by Mint/X11s: Differential Functions of Mint Isoforms (2002) (103)
- MDGAs interact selectively with neuroligin-2 but not other neuroligins to regulate inhibitory synapse development (2012) (102)
- Genetic Analysis of Mint/X11 Proteins: Essential Presynaptic Functions of a Neuronal Adaptor Protein Family (2006) (101)
- Differential but convergent functions of Ca2+ binding to synaptotagmin-1 C2 domains mediate neurotransmitter release (2009) (101)
- Convergence and divergence in the mechanism of SNARE binding by Sec1/Munc18-like proteins (2002) (101)
- Synaptic Vesicle Traffic: Rush Hour in the Nerve Terminal (1993) (101)
- Structural Basis for a Munc13–1 Homodimer to Munc13–1/RIM Heterodimer Switch (2006) (101)
- Munc18–1 stabilizes syntaxin 1, but is not essential for syntaxin 1 targeting and SNARE complex formation (2005) (100)
- Synaptotagmin‐7 is a principal Ca2+ sensor for Ca2+‐induced glucagon exocytosis in pancreas (2009) (100)
- Neuroligins Sculpt Cerebellar Purkinje-Cell Circuits by Differential Control of Distinct Classes of Synapses (2015) (100)
- How to Make an Active Zone: Unexpected Universal Functional Redundancy between RIMs and RIM-BPs (2016) (99)
- ELKS2α/CAST Deletion Selectively Increases Neurotransmitter Release at Inhibitory Synapses (2009) (99)
- First cysteine-rich repeat in ligand-binding domain of low density lipoprotein receptor binds Ca2+ and monoclonal antibodies, but not lipoproteins. (1987) (98)
- Neuroligins/LRRTMs prevent activity- and Ca2+/calmodulin-dependent synapse elimination in cultured neurons (2011) (98)
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- Lipid-Anchored SNAREs Lacking Transmembrane Regions Fully Support Membrane Fusion during Neurotransmitter Release (2013) (98)
- A role for Mints in transmitter release: Mint 1 knockout mice exhibit impaired GABAergic synaptic transmission (2003) (97)
- Genetic analysis of synaptotagmin-7 function in synaptic vesicle exocytosis (2008) (97)
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- Structural basis for the evolutionary inactivation of Ca2+ binding to synaptotagmin 4 (2004) (95)
- Deletion of α‐neurexins does not cause a major impairment of axonal pathfinding or synapse formation (2007) (95)
- A conformational switch in the Piccolo C2A domain regulated by alternative splicing (2004) (94)
- Synaptogyrins Regulate Ca2+-dependent Exocytosis in PC12 Cells* (1999) (94)
- Dynamin I is a Ca(2+)-sensitive phospholipid-binding protein with very high affinity for protein kinase C. (1994) (94)
- RIM genes differentially contribute to organizing presynaptic release sites (2012) (94)
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- The structure of the human synapsin I gene and protein. (1990) (93)
- The multisubunit structure of synaptophysin. Relationship between disulfide bonding and homo-oligomerization. (1990) (93)
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- Evolutionarily Conserved Multiple C2 Domain Proteins with Two Transmembrane Regions (MCTPs) and Unusual Ca2+ Binding Properties* (2005) (92)
- Neurexins Are Functional α-Latrotoxin Receptors (1999) (92)
- Synapsins I and II Are ATP-binding Proteins with Differential Ca2+ Regulation* (1998) (92)
- Neurexin Iα Is a Major α-Latrotoxin Receptor That Cooperates in α-Latrotoxin Action* (1998) (91)
- β-Neurexins Control Neural Circuits by Regulating Synaptic Endocannabinoid Signaling (2015) (91)
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- Region-Specific Phosphorylation of Rabphilin in Mossy Fiber Nerve Terminals of the Hippocampus (1998) (87)
- Synapsin III, a Novel Synapsin with an Unusual Regulation by Ca2+ * (1998) (87)
- Human endomembrane H+ pump strongly resembles the ATP-synthetase of Archaebacteria. (1989) (87)
- RIM1α and RIM1β Are Synthesized from Distinct Promoters of the RIM1 Gene to Mediate Differential But Overlapping Synaptic Functions (2008) (87)
- rab3A attachment to the synaptic vesicle membrane mediated by a conserved polyisoprenylated carboxy-terminal sequence (1991) (86)
- SVOP, an Evolutionarily Conserved Synaptic Vesicle Protein, Suggests Novel Transport Functions of Synaptic Vesicles (1998) (86)
- How to make a synaptic ribbon: RIBEYE deletion abolishes ribbons in retinal synapses and disrupts neurotransmitter release (2016) (86)
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- Evolution of CASK into a Mg2+-Sensitive Kinase (2010) (86)
- Synaptotagmin Regulation of Coated Pit Assembly* (2000) (85)
- Synaptotagmin function in dense core vesicle exocytosis studied in cracked PC12 cells (2002) (85)
- Conditional neuroligin-2 knockout in adult medial prefrontal cortex links chronic changes in synaptic inhibition to cognitive impairments (2015) (84)
- NMR analysis of the structure of synaptobrevin and of its interaction with syntaxin (1999) (83)
- Novel SCAMPs Lacking NPF Repeats: Ubiquitous and Synaptic Vesicle-Specific Forms Implicate SCAMPs in Multiple Membrane-Trafficking Functions (2000) (82)
- Mint 3: a ubiquitous mint isoform that does not bind to munc18-1 or -2. (1998) (82)
- Homo- and Heterodimerization of Synapsins* (1999) (81)
- Deconstructing complexin function in activating and clamping Ca2+-triggered exocytosis by comparing knockout and knockdown phenotypes (2013) (81)
- Unusually rapid evolution of Neuroligin-4 in mice (2008) (81)
- Structural Basis for Teneurin Function in Circuit-Wiring: A Toxin Motif at the Synapse (2018) (81)
- Structural Basis of Latrophilin-FLRT-UNC5 Interaction in Cell Adhesion. (2015) (81)
- Extracellular domains of alpha-neurexins participate in regulating synaptic transmission by selectively affecting N- and P/Q-type Ca2+ channels. (2005) (80)
- α‐Latrotoxin action probed with recombinant toxin: receptors recruit α‐latrotoxin but do not transduce an exocytotic signal (1998) (79)
- RIM1α phosphorylation at serine-413 by protein kinase A is not required for presynaptic long-term plasticity or learning (2008) (79)
- RIM-BPs Mediate Tight Coupling of Action Potentials to Ca2+-Triggered Neurotransmitter Release (2015) (78)
- Synapsins regulate use-dependent synaptic plasticity in the calyx of Held by a Ca2+/calmodulin-dependent pathway. (2006) (78)
- C-Terminal Complexin Sequence Is Selectively Required for Clamping and Priming But Not for Ca2+ Triggering of Synaptic Exocytosis (2012) (78)
- CSPα-deficiency causes massive and rapid photoreceptor degeneration (2006) (78)
- Structure of synaptogyrin (p29) defines novel synaptic vesicle protein (1995) (78)
- Characterization of tissue-specific transcription by the human synapsin I gene promoter. (1991) (78)
- Cyclosporine A-induced hypertension involves synapsin in renal sensory nerve endings. (2000) (77)
- Neurotransmitter Release at the Thalamocortical Synapse Instructs Barrel Formation But Not Axon Patterning in the Somatosensory Cortex (2012) (77)
- Role of alpha-synuclein in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism in mice. (2003) (76)
- Synaptotagmin-7-Mediated Asynchronous Release Boosts High-Fidelity Synchronous Transmission at a Central Synapse (2017) (76)
- cDNA cloning and expression of the alpha and beta subunits of rat Rab geranylgeranyl transferase. (1993) (76)
- Presynaptic Neuronal Pentraxin Receptor Organizes Excitatory and Inhibitory Synapses (2017) (76)
- Distinct circuit-dependent functions of presynaptic neurexin-3 at GABAergic and glutamatergic synapses (2015) (75)
- The structure of cytochrome b561, a secretory vesicle‐specific electron transport protein. (1988) (75)
- Human 67-kDa calelectrin contains a duplication of four repeats found in 35-kDa lipocortins. (1988) (74)
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- Push-and-pull regulation of the fusion pore by synaptotagmin-7 (2010) (74)
- Calcium regulation of neurotransmitter release: reliably unreliable? (1997) (74)
- Cloning, characterization, and expression of a novel GDP dissociation inhibitor isoform from skeletal muscle (1994) (73)
- Redundant functions of RIM1alpha and RIM2alpha in Ca(2+)-triggered neurotransmitter release. (2006) (72)
- The G Protein-coupled Receptor CL1 Interacts Directly with Proteins of the Shank Family* (2000) (72)
- Membrane-Tethered Monomeric Neurexin LNS-Domain Triggers Synapse Formation (2013) (71)
- RIM function in short- and long-term synaptic plasticity. (2005) (70)
- Neurons generated by direct conversion of fibroblasts reproduce synaptic phenotype caused by autism-associated neuroligin-3 mutation (2013) (70)
- Calsyntenins function as synaptogenic adhesion molecules in concert with neurexins. (2014) (70)
- Synaptotagmin-1 and -7 Are Redundantly Essential for Maintaining the Capacity of the Readily-Releasable Pool of Synaptic Vesicles (2015) (70)
- Phosphorylation of synaptotagmin I by casein kinase II. (1993) (69)
- Long-term potentiation in mice lacking synapsins (1995) (69)
- Structure of the Janus-faced C2B domain of rabphilin (1999) (69)
- Direct Interaction of Alzheimer’s Disease-related Presenilin 1 with Armadillo Protein p0071* (1999) (69)
- Ca(2+)-dependent conformational change in synaptotagmin I. (1994) (69)
- Fatty acylation of synaptotagmin in PC12 cells and synaptosomes. (1996) (68)
- Common EF‐hand motifs in cholinesterases and neuroligins suggest a role for Ca2+ binding in cell surface associations (2008) (66)
- Unique versus Redundant Functions of Neuroligin Genes in Shaping Excitatory and Inhibitory Synapse Properties (2017) (66)
- Differential distributions of novel synaptotagmins: Comparison to synapsins (1995) (65)
- Conditional ablation of neuroligin-1 in CA1 pyramidal neurons blocks LTP by a cell-autonomous NMDA receptor-independent mechanism (2016) (64)
- Functional Analysis of Conserved Structural Elements in Yeast Syntaxin Vam3p* (2001) (64)
- Cellugyrin, a Novel Ubiquitous Form of Synaptogyrin That Is Phosphorylated by pp60c- src * (1998) (64)
- Genetic evidence for a protein-kinase-A-mediated presynaptic component in NMDA-receptor-dependent forms of long-term synaptic potentiation. (2005) (64)
- The structure of the ligand-binding domain of neurexin Ibeta: regulation of LNS domain function by alternative splicing. (1999) (63)
- Function of Rab3 GDP–GTP Exchange (1997) (63)
- Alternative Splicing of Presynaptic Neurexins Differentially Controls Postsynaptic NMDA and AMPA Receptor Responses (2019) (63)
- Cellular distribution of three mammalian Ca2+‐binding proteins related to Torpedo calelectrin. (1984) (62)
- Deletion of Mint Proteins Decreases Amyloid Production in Transgenic Mouse Models of Alzheimer's Disease (2008) (62)
- Retinoic Acid and LTP Recruit Postsynaptic AMPA Receptors Using Distinct SNARE-Dependent Mechanisms (2015) (61)
- Analysis of conditional heterozygous STXBP1 mutations in human neurons. (2015) (61)
- High Affinity Binding of α-Latrotoxin to Recombinant Neurexin Iα (*) (1995) (61)
- Ca 2 binding to synaptotagmin : how many Ca 2 ions bind to the tip of a C 2-domain ? (2013) (60)
- Rab3B protein is required for long-term depression of hippocampal inhibitory synapses and for normal reversal learning (2011) (60)
- Postsynaptic adhesion GPCR latrophilin-2 mediates target recognition in entorhinal-hippocampal synapse assembly (2017) (60)
- The LDL receptor in familial hypercholesterolemia: use of human mutations to dissect a membrane protein. (1986) (60)
- Leucine-Rich Repeat Transmembrane Proteins Are Essential for Maintenance of Long-Term Potentiation (2013) (60)
- Microsecond Dissection of Neurotransmitter Release: SNARE-Complex Assembly Dictates Speed and Ca2+ Sensitivity (2014) (59)
- Carbonic anhydrase-related protein CA10 is an evolutionarily conserved pan-neurexin ligand (2017) (59)
- The Active Zone Protein Family ELKS Supports Ca2+ Influx at Nerve Terminals of Inhibitory Hippocampal Neurons (2014) (59)
- Endocannabinoid-Mediated Long-Term Plasticity Requires cAMP/PKA Signaling and RIM1α (2007) (58)
- Calelectrin self‐aggregates and promotes membrane aggregation in the presence of calcium. (1982) (58)
- Specific factors in blood from young but not old mice directly promote synapse formation and NMDA-receptor recruitment (2019) (58)
- Specificity of Ca2+-dependent protein interactions mediated by the C2A domains of synaptotagmins. (2000) (57)
- Titration of Syntaxin1 in Mammalian Synapses Reveals Multiple Roles in Vesicle Docking, Priming, and Release Probability (2013) (57)
- The fragile X mutation impairs homeostatic plasticity in human neurons by blocking synaptic retinoic acid signaling (2018) (57)
- β-Neurexin Is a Ligand for the Staphylococcus aureus MSCRAMM SdrC (2010) (57)
- Distinct Ca(2+)-dependent properties of the first and second C2-domains of synaptotagmin I. (1996) (57)
- Proteasome Inhibition Alleviates SNARE-Dependent Neurodegeneration (2012) (56)
- An unusual C2‐domain in the active‐zone protein piccolo: implications for Ca2+ regulation of neurotransmitter release (2001) (56)
- Synaptic neurexin-1 assembles into dynamically regulated active zone nanoclusters (2019) (56)
- Cleavage of cellubrevin by tetanus toxin does not affect fusion of early endosomes. (1993) (55)
- Analysis of SCAMP1 Function in Secretory Vesicle Exocytosis by Means of Gene Targeting in Mice* (1999) (55)
- Transdifferentiation of human adult peripheral blood T cells into neurons (2018) (55)
- Domain structure of a mammalian myosin I beta. (1994) (55)
- Two novel annexins from Drosophila melanogaster. Cloning, characterization, and differential expression in development. (1990) (54)
- Synaptotagmin-7 phosphorylation mediates GLP-1–dependent potentiation of insulin secretion from β-cells (2015) (54)
- Modulation of excitation on parvalbumin interneurons by neuroligin-3 regulates the hippocampal network (2016) (53)
- α-Latrotoxin Stimulates a Novel Pathway of Ca2+-Dependent Synaptic Exocytosis Independent of the Classical Synaptic Fusion Machinery (2009) (53)
- Extended Synaptotagmin (ESyt) Triple Knock-Out Mice Are Viable and Fertile without Obvious Endoplasmic Reticulum Dysfunction (2016) (52)
- Evidence for SNARE zippering during Ca2+-triggered exocytosis in PC12 cells (2003) (52)
- The cDNA and derived amino acid sequences for rat and human synaptophysin. (1987) (51)
- Complexin Activates Exocytosis of Distinct Secretory Vesicles Controlled by Different Synaptotagmins (2013) (51)
- Continuous and Discrete Neuron Types of the Adult Murine Striatum (2019) (50)
- CSPalpha-deficiency causes massive and rapid photoreceptor degeneration. (2006) (50)
- Pathogenic Mechanism of an Autism-Associated Neuroligin Mutation Involves Altered AMPA-Receptor Trafficking (2015) (50)
- Expression of C1ql3 in Discrete Neuronal Populations Controls Efferent Synapse Numbers and Diverse Behaviors (2016) (50)
- Mechanics of membrane fusion (1998) (49)
- Newly Synthesized Phosphatidylinositol Phosphates Are Required for Synaptic Norepinephrine but Not Glutamate or γ-Aminobutyric Acid (GABA) Release* (1998) (49)
- Neuroligin-4 Regulates Excitatory Synaptic Transmission in Human Neurons (2019) (49)
- Synaptotagmin-7 Is Essential for Ca2+-Triggered Delayed Asynchronous Release But Not for Ca2+-Dependent Vesicle Priming in Retinal Ribbon Synapses (2015) (49)
- Crystal Structure of the Second LNS/LG Domain from Neurexin 1α (2006) (48)
- Synaptophysin: structure of the human gene and assignment to the X chromosome in man and mouse. (1990) (48)
- Neuroligin-1 Signaling Controls LTP and NMDA Receptors by Distinct Molecular Pathways (2019) (48)
- Molecular Neuroscience in the 21st Century: A Personal Perspective (2017) (47)
- Proteolytic Processing of Amyloid-β Precursor Protein by Secretases Does Not Require Cell Surface Transport* (2004) (47)
- Munc 13 C 2 B domain is an activity-dependent Ca 2 + regulator of synaptic exocytosis (2010) (45)
- Synaptotagmin 13: structure and expression of a novel synaptotagmin. (2001) (45)
- Developmentally Regulated Alternative Splicing in a Novel Synaptojanin* (1998) (44)
- Polypeptide composition of the alpha-latrotoxin receptor. High affinity binding protein consists of a family of related high molecular weight polypeptides complexed to a low molecular weight protein. (1993) (44)
- A central amygdala to zona incerta projection is required for acquisition and remote recall of conditioned fear memory (2018) (44)
- Conditional deletion of L1CAM in human neurons impairs both axonal and dendritic arborization and action potential generation (2016) (43)
- Structure and Ca²⁺-binding properties of the tandem C₂ domains of E-Syt2. (2014) (43)
- NECABs: a family of neuronal Ca2+-binding proteins with an unusual domain structure and a restricted expression pattern (2002) (43)
- Genetic Analysis of α-Latrotoxin Receptors Reveals Functional Interdependence of CIRL/Latrophilin 1 and Neurexin 1α* (2002) (42)
- Role of calcium in neurotransmitter release evoked by α-latrotoxin or hypertonic sucrose (2000) (42)
- CSPα promotes SNARE-complex assembly by chaperoning SNAP-25 during synaptic activity (2011) (42)
- Synaptic vesicle proteins in exocytosis: what do we know? (1993) (42)
- Two distinct domains in hsc70 are essential for the interaction with the synaptic vesicle cysteine string protein. (1999) (42)
- C-terminal domain of mammalian complexin-1 localizes to highly curved membranes (2016) (41)
- Structural characterization of recombinant soluble rat neuroligin 1: mapping of secondary structure and glycosylation by mass spectrometry. (2004) (41)
- Role of electrostatic and hydrophobic interactions in Ca(2+)-dependent phospholipid binding by the C(2)A-domain from synaptotagmin I. (2002) (40)
- Inactivation of presenilins causes pre-synaptic impairment prior to post-synaptic dysfunction (2010) (40)
- Developmental plasticity shapes synaptic phenotypes of autism-associated neuroligin-3 mutations in the calyx of Held (2017) (39)
- ELKS1 localizes the synaptic vesicle priming protein bMunc13-2 to a specific subset of active zones (2017) (39)
- Three-dimensional structure of an independently folded extracellular domain of human amyloid-beta precursor protein. (2004) (38)
- Calelectrin, a Calcium‐Dependent Membrane‐Binding Protein Associated with Secretory Granules in Torpedo Cholinergic Electromotor Nerve Endings and Rat Adrenal Medulla (1983) (38)
- Direct Visualization of Trans-Synaptic Neurexin–Neuroligin Interactions during Synapse Formation (2014) (38)
- RIM1α and Interacting Proteins Involved in Presynaptic Plasticity Mediate Prepulse Inhibition and Additional Behaviors Linked to Schizophrenia (2010) (38)
- α-Latrotoxin Receptor CIRL/Latrophilin 1 (CL1) Defines an Unusual Family of Ubiquitous G-protein-linked Receptors (1998) (38)
- Solution structure of the Vam7p PX domain. (2002) (38)
- α‐latrotoxin triggers transmitter release via direct insertion into the presynaptic plasma membrane (2000) (37)
- Dissection of Synapse Induction by Neuroligins EFFECT OF A NEUROLIGIN MUTATION ASSOCIATED WITH AUTISM* (2005) (37)
- Cerebellins are differentially expressed in selective subsets of neurons throughout the brain (2017) (36)
- Structures of C1q-like proteins reveal unique features among the C1q/TNF superfamily. (2015) (36)
- Deletion of LRRTM1 and LRRTM2 in adult mice impairs basal AMPA receptor transmission and LTP in hippocampal CA1 pyramidal neurons (2018) (36)
- IGF1-Dependent Synaptic Plasticity of Mitral Cells in Olfactory Memory during Social Learning (2017) (35)
- Synaptotagmin-12 Phosphorylation by cAMP-Dependent Protein Kinase Is Essential for Hippocampal Mossy Fiber LTP (2013) (35)
- Genetic Ablation of All Cerebellins Reveals Synapse Organizer Functions in Multiple Regions Throughout the Brain (2018) (35)
- Analysis of the Catalytic Domain of Phosphatidylinositol 4-Kinase Type II* (2002) (34)
- The Synaptic Vesicle Cycle in the Nerve Terminal (1999) (33)
- Differential Signaling Mediated by ApoE2, ApoE3, and ApoE4 in Human Neurons Parallels Alzheimer's Disease Risk (2019) (33)
- Synaptic targeting domains of synapsin I revealed by transgenic expression in photoreceptor cells. (1994) (33)
- Characterization of Calelectrin, a Ca2+‐Binding Protein Isolated from the Electric Organ of Torpedo marmorata (1985) (33)
- Structural and Mutational Analysis of Functional Differentiation between Synaptotagmins-1 and -7 (2010) (33)
- C-terminal ECFP Fusion Impairs Synaptotagmin 1 Function (2005) (32)
- Unexpected Ca2+-binding properties of synaptotagmin 9. (2004) (32)
- Calmodulin Suppresses Synaptotagmin-2 Transcription in Cortical Neurons* (2010) (32)
- Cysteine string protein‐α is essential for the high calcium sensitivity of exocytosis in a vertebrate synapse (2008) (32)
- Solution structure of the RIM1alpha PDZ domain in complex with an ELKS1b C-terminal peptide. (2005) (32)
- Exceptionally tight membrane-binding may explain the key role of the synaptotagmin-7 C2A domain in asynchronous neurotransmitter release (2017) (31)
- Neuromodulator Signaling Bidirectionally Controls Vesicle Numbers in Human Synapses (2019) (31)
- RIM1 and RIM2 redundantly determine Ca2+ channel density and readily releasable pool size at a large hindbrain synapse. (2015) (31)
- Genetic Dissection of the Amyloid Precursor Protein in Developmental Function and Amyloid Pathogenesis*♦ (2010) (31)
- Neurexin I alpha is a major alpha-latrotoxin receptor that cooperates in alpha-latrotoxin action. (1998) (31)
- The cell biology of synapse formation (2021) (30)
- Structure of the murine rab3A gene: correlation of genomic organization with antibody epitopes. (1993) (30)
- Synaptic function of nicastrin in hippocampal neurons (2014) (29)
- Neurexins cluster Ca2+ channels within the presynaptic active zone (2020) (29)
- Rab3 Proteins Involved in Vesicle Biogenesis and Priming in Embryonic Mouse Chromaffin Cells (2010) (28)
- Synaptic retinoic acid receptor signaling mediates mTOR-dependent metaplasticity that controls hippocampal learning (2019) (28)
- Neuroligins Are Selectively Essential for NMDAR Signaling in Cerebellar Stellate Interneurons (2016) (28)
- Distinct Ca and Sr Binding Properties of Synaptotagmins DEFINITION OF CANDIDATE Ca SENSORS FOR THE FAST AND SLOW COMPONENTS OF NEUROTRANSMITTER RELEASE* (1995) (28)
- LAR receptor phospho-tyrosine phosphatases regulate NMDA-receptor responses (2020) (27)
- Core structure, internal osmotic pressure and irreversible structural changes of chromaffin granules during osmometer behaviour. (1982) (27)
- Synaptotagmin-11 mediates a vesicle trafficking pathway that is essential for development and synaptic plasticity (2019) (27)
- Activity-Dependent IGF-1 Exocytosis Is Controlled by the Ca 2+ -Sensor (2011) (27)
- The relation of protein binding to function: what is the significance of munc18 and synaptotagmin binding to syntaxin 1, and where are the corresponding binding sites? (2000) (27)
- The Top Loops of the C2 Domains from Synaptotagmin and Phospholipase A2 Control Functional Specificity* (2001) (27)
- Differential expression of active zone proteins in neuromuscular junctions suggests functional diversification (2006) (27)
- Synapsin II. Mapping of a domain in the NH2-terminal region which binds to small synaptic vesicles. (1990) (26)
- Membrane fusion as a team effort (2007) (26)
- Persistent transcriptional programmes are associated with remote memory (2020) (25)
- A Synaptic Circuit Required for Acquisition but Not Recall of Social Transmission of Food Preference (2020) (25)
- A Trio of Active Zone Proteins Comprised of RIM-BPs, RIMs, and Munc13s Governs Neurotransmitter Release. (2020) (25)
- Differential Signaling Mediated by ApoE2, ApoE3, and ApoE4 in Human Neurons Parallels Alzheimer’s Disease Risk (2018) (24)
- The Morphological and Molecular Nature of Synaptic Vesicle Priming at Presynaptic Active Zones (2014) (23)
- Acute reduction in oxygen tension enhances the induction of neurons from human fibroblasts (2013) (23)
- Autism-associated neuroligin-4 mutation selectively impairs glycinergic synaptic transmission in mouse brainstem synapses (2018) (22)
- Are neuronal SNARE proteins Ca2+ sensors? (2005) (22)
- The Neurobiology of Opioid Addiction and the Potential for Prevention Strategies. (2018) (22)
- Embryonic neuronal death due to neurotrophin and neurotransmitter deprivation occurs independent of Apaf-1 (2001) (22)
- Evolutionary conservation of complexins: from choanoflagellates to mice (2015) (22)
- Rat homologues of yeast sec7p. (1997) (22)
- Purification and expression of gCap39. An intracellular and secreted Ca2(+)-dependent actin-binding protein enriched in mononuclear phagocytes. (1990) (22)
- Postsynaptic N-methyl-D-aspartate receptor function requires-neurexins (2004) (22)
- A toolbox of nanobodies developed and validated for use as intrabodies and nanoscale immunolabels in mammalian brain neurons (2019) (22)
- Complexins Regulate a Late Step in Ca 2 1-Dependent Neurotransmitter Release cellular (2001) (22)
- Stimulus-dependent dynamic homo- and heteromultimerization of synaptobrevin/VAMP and synaptophysin. (2004) (21)
- Direct Reprogramming of Human Neurons Identifies MARCKSL1 as a Pathogenic Mediator of Valproic Acid-Induced Teratogenicity. (2019) (21)
- Stable expression of truncated inositol 1,4,5-trisphosphate receptor subunits in 3T3 fibroblasts. Coordinate signaling changes and differential suppression of cell growth and transformation. (1994) (21)
- Pharmacology of neurotransmitter release (2008) (21)
- Neurexins are functional alpha-latrotoxin receptors. (1999) (20)
- Crystal structure of the RIM2 C2A-domain at 1.4 A resolution. (2005) (20)
- Ablation of All Synaptobrevin vSNAREs Blocks Evoked But Not Spontaneous Neurotransmitter Release at Neuromuscular Synapses (2019) (19)
- Calcium-promoted resonance energy transfer between fluorescently labeled proteins during aggregation of chromaffin granule membranes. (1982) (19)
- Reproducibility: Experimental mismatch in neural circuits (2015) (19)
- Calelectrins are a ubiquitous family of Ca2+-binding proteins purified by Ca2+-dependent hydrophobic affinity chromatography by a mechanism distinct from that of calmodulin. (1984) (19)
- Characterization of rabphilin phosphorylation using phospho-specific antibodies (2001) (19)
- Synaptic Function of Rab11Fip5: Selective Requirement for Hippocampal Long-Term Depression (2015) (18)
- FoxO3 regulates neuronal reprogramming of cells from postnatal and aging mice (2016) (18)
- Lipid and protein interactions in ca-promoted aggregation and fusion of chromaffin granule membranes. (1982) (18)
- Retinoic Acid Receptor RARα-Dependent Synaptic Signaling Mediates Homeostatic Synaptic Plasticity at the Inhibitory Synapses of Mouse Visual Cortex (2018) (18)
- Role of calcium in neurotransmitter release evoked by alpha-latrotoxin or hypertonic sucrose. (2000) (18)
- Latrophilin GPCR signaling mediates synapse formation (2021) (18)
- SPARCL1 Promotes Excitatory But Not Inhibitory Synapse Formation and Function Independent of Neurexins and Neuroligins (2020) (18)
- Alternative splicing controls teneurin-latrophilin interaction and synapse specificity by a shape-shifting mechanism (2020) (18)
- Crystal Structure of the RIM1α C2B Domain at 1.7 Å Resolution (2007) (18)
- Efficient stimulus-secretion coupling at ribbon synapses requires RIM-binding protein tethering of L-type Ca2+ channels (2017) (17)
- High affinity binding of alpha-latrotoxin to recombinant neurexin I alpha. (1995) (17)
- Synaptic Vesicles: An Organelle Comes of Age (2006) (17)
- RTN4/NoGo-receptor binding to BAI adhesion-GPCRs regulates neuronal development (2021) (17)
- Inositol hexakisphosphate suppresses excitatory neurotransmission via synaptotagmin-1 C2B domain in the hippocampal neuron (2012) (17)
- Ubiquitin–Synaptobrevin Fusion Protein Causes Degeneration of Presynaptic Motor Terminals in Mice (2015) (17)
- Pro-neuronal activity of Myod1 due to promiscuous binding to neuronal genes (2020) (16)
- Neuronal Calcium Sensor Synaptotagmin-9 Is Not Involved in the Regulation of Glucose Homeostasis or Insulin Secretion (2010) (16)
- Calelectrin in human blood cells. (1983) (16)
- Molecular approaches to synaptic vesicle exocytosis. (1993) (16)
- Latrophilin-2 and latrophilin-3 are redundantly essential for parallel-fiber synapse function in cerebellum (2020) (15)
- Cross-platform validation of neurotransmitter release impairments in schizophrenia patient-derived NRXN1-mutant neurons (2020) (15)
- Molecular Analysis of Inositol 1,4,5-Trisphosphate Receptors (1993) (15)
- Truth in Science Publishing: A Personal Perspective (2016) (15)
- Cbln2 and Cbln4 are expressed in distinct medial habenula-interpeduncular projections and contribute to different behavioral outputs (2018) (15)
- High-level expression of the 32.5-kilodalton calelectrin in ductal epithelia as revealed by immunocytochemistry. (1986) (15)
- GluD1 is a signal transduction device disguised as an ionotropic receptor. (2021) (14)
- Implications for Intracellular Trafficking (1999) (14)
- Deorphanizing FAM19A proteins as pan-neurexin ligands with an unusual biosynthetic binding mechanism (2020) (13)
- lnsP3 receptor turnaround (1990) (13)
- Evolution of the Autism-Associated Neuroligin-4 Gene Reveals Broad Erosion of Pseudoautosomal Regions in Rodents (2020) (13)
- Neurexophilin Binding to α-Neurexins (1998) (12)
- Delayed onset of hyperglycaemia in a mouse model with impaired glucagon secretion demonstrates that dysregulated glucagon secretion promotes hyperglycaemia and type 2 diabetes (2011) (12)
- Evolutionary conservation and structural determinants of the calelectrins (annexins). (1990) (12)
- The chromaffin granule as a model for membrane fusion: implications for exocytosis. (1983) (12)
- Mammary gland Ca2+‐binding (‐dependent) proteins: Identification as calelectrins and calpactin I/p36 (1988) (12)
- Multiple signaling pathways are essential for synapse formation induced by synaptic adhesion molecules (2021) (12)
- Erratum: Synaptotagmins: C2-domain proteins that regulate membrane traffic (Neuron (1996) 17 (379-388)) (1996) (11)
- Region-specific deletions of RIM1 reproduce a subset of global RIM1α−/− phenotypes (2012) (10)
- The Molecular Machinery of Neurotransmitter Release (2014) (10)
- Assignment of the 1H, 15N and13 C resonances of the calcium-free and calcium-bound forms of the first C2-domain of synaptotagmin I (1997) (10)
- The conditional KO approach: Cre/Lox technology in human neurons (2016) (10)
- Characteristics and determinants of osmotic lysis in chromaffin granules. (1983) (10)
- Compartment-Specific Neurexin Nanodomains Orchestrate Tripartite Synapse Assembly (2020) (10)
- Mapping of synapsin II (SYN2) genes to human chromosome 3p and mouse chromosome 6 band F. (1995) (9)
- Structural Basis for a Munc13-1 Homodimer - Munc13-1 - RIM Heterodimer Switch: C2-domains as Versatile Protein-Protein Interaction Modules (2006) (9)
- RIM‐binding proteins recruit BK‐channels to presynaptic release sites adjacent to voltage‐gated Ca2+‐channels (2018) (9)
- The calelectrins: new and ubiquitous Ca2+-regulated proteins with a possible role in cytotic processes. (1984) (9)
- Testing the SNARE/SM protein model of membrane fusion (2010) (8)
- Astrocytic Neurexin-1 Orchestrates Functional Synapse Assembly (2020) (8)
- Cannabinoid receptor activation acutely increases synaptic vesicle numbers by activating synapsins in human synapses (2021) (8)
- Identification, expression, and crystallization of the protease‐resistant conserved domain of synapsin I (1997) (8)
- Structures of neurexophilin–neurexin complexes reveal a regulatory mechanism of alternative splicing (2019) (8)
- Conditional deletion of L1CAM in human neurons impairs both axonal and dendritic arborization and action potential generation (2016) (8)
- Anatomical and Behavioral Investigation of C1ql3 in the Mouse Suprachiasmatic Nucleus (2017) (7)
- THE C2B-DOMAIN OF RABPHILIN: STRUCTURAL VARIATIONS IN A JANUS-FACED DOMAIN (1999) (7)
- Crystal Structure of the RIM 1 R C 2 B Domain at 1 . 7 Å Resolution (7)
- Dysfunction of parvalbumin neurons in the cerebellar nuclei produces an action tremor. (2020) (7)
- Crystal structure of the RIM1alpha C2B domain at 1.7 A resolution. (2007) (7)
- Evidence for a divalent cation dependent catecholamine storage complex in chromaffin granules. (1983) (7)
- Efficient generation of dopaminergic induced neuronal cells with midbrain characteristics (2021) (7)
- Discrete and Continuous Cell Identities of the Adult Murine Striatum (2019) (6)
- Building bridges between neuroscientific evidence and policy (2015) (6)
- An interview with Randy Schekman and Thomas Südhof. (2014) (6)
- A simple Ca2+-imaging approach to neural network analyses in cultured neurons (2020) (6)
- Ultrastructure of Synapses in the Mammalian (2012) (6)
- [3] Purification of calelectrins (1987) (6)
- Neurexins regulate presynaptic GABAB-receptors at central synapses (2021) (5)
- Synaptic vesicles. (1989) (5)
- Treatment of a genetic brain disease by CNS-wide microglia replacement (2022) (5)
- InsP3 receptor turnaround. (1990) (5)
- Conditional knockout of Nlgn2 in the adult medial prefrontal cortex (mPFC) induces delayed loss of inhibitory synapses (2015) (5)
- Composition of Synaptic Vesicles (1999) (5)
- CAPS in search of a lost function. (2005) (5)
- Rapid generation of functional and homogeneous excitatory human forebrain neurons using Neurogenin-2 (Ngn2) (2018) (5)
- The Perils of Navigating Activity-Dependent Alternative Splicing of Neurexins (2021) (4)
- Cerebellins meet neurexins (Commentary on Matsuda & Yuzaki) (2011) (4)
- Functional architecture of the synaptic transducers at a central glutamatergic synapse (2020) (4)
- Author response: Native α-synuclein induces clustering of synaptic-vesicle mimics via binding to phospholipids and synaptobrevin-2/VAMP2 (2013) (4)
- Harness the power of endogenous neural stem cells by biomaterials to treat spinal cord injury (2015) (4)
- P1-284 Cleavage of APP and APLP's by BACE 1 (2004) (4)
- Bi-allelic variants in TSPOAP1, encoding the active zone protein RIMBP1, cause autosomal recessive dystonia (2020) (3)
- Insulin Release : Some Molecular Requisites Molecular Determinants of Regulated Exocytosis (2002) (3)
- Building Bridges through Science (2017) (3)
- Crystal Structure of the second LNS/LG domain from Neurexin 1 alpha (2006) (3)
- Scientific Background Machinery Regulating Vesicle Traffic, A Major Transport System in our Cells (2013) (3)
- GENERATION OF TRANSGENIC MICE FOR IN VIVO DETECTION OF INSULIN-CONTAINING GRANULE EXOCYTOSIS AND QUANTIFICATION OF INSULIN SECRETION (2009) (3)
- Synaptogenesis: When Long-Distance Relations Become Intimate (2006) (3)
- The synapse : a subject collection from Cold Spring Harbor perspectives in biology (2012) (2)
- ApoE2, ApoE3 and ApoE4 Differentially Impact Multiple Signaling Pathways Regulating Synaptogenesis (2018) (2)
- Nanometer-Resolution Long-term Tracking of Single Cargos Reveals Dynein Motor Mechanisms (2022) (2)
- Temperature-induced lysis of chromaffin granules provides evidence against the two-pool hypothesis of catecholamine storage. (1983) (2)
- RTN4/NoGo-receptor binding to BAI adhesion-GPCRs regulates neuronal development (2022) (2)
- Synaptotagmin 1 C 2 B Domain Triggers Fast Exocytosis without Stimulating SNARE Interactions (2003) (2)
- A toolbox of nanobodies developed and validated for diverse neuroscience research applications (2019) (2)
- RIBEYE B-Domain Is Essential for RIBEYE A-Domain Stability and Assembly of Synaptic Ribbons (2022) (2)
- Metal Binding Motifs in Cholinesterases and Neuroligins (1998) (2)
- Cerebellin-2 Regulates a Serotonergic Dorsal Raphe Circuit that Controls Compulsive Behaviors (2021) (2)
- Crystal Structure of the RIM2 C2A-domain at 1.4 angstrom Resolution (2005) (2)
- A systematic approach to studying synaptic function in vertebrates. (1995) (2)
- C2-Domains in Ca2+-Signaling (2003) (2)
- Postsynaptic synucleins mediate vesicular exocytosis of endocannabinoids (2021) (1)
- Transsynaptic cerebellin 4-neogenin 1 signaling mediates LTP in the mouse dentate gyrus. (2022) (1)
- Manu Sharma Proteasome Inhibition Alleviates SNARE-Dependent Neurodegeneration (2012) (1)
- Structure of the teneurin-latrophilin complex: Alternative splicing controls synapse specificity by a novel mechanism (2020) (1)
- New neurexin iso-Seq paper in Neuron WEDNESDAY, MARCH 19, 2014 Assessment of Highly Complex Alternative Splicing of Neurexins Performed with SMRT Sequencing (2014) (1)
- [The molecular machinery of neurotransmitter secretion]. (2015) (1)
- α-Synuclein, CSPα, SNAREs and Neuroprotection in vivo (2008) (1)
- Structural Basis of Latrop hilin-FLRT-UNC 5 Interaction in Cell Adhesion Graphical (2015) (1)
- Author response: LAR receptor phospho-tyrosine phosphatases regulate NMDA-receptor responses (2020) (1)
- Structural and Functional Studies of Latrophilin‐Family Adhesion G‐Protein Coupled Receptors (2017) (1)
- Molecular self-avoidance in synaptic neurexin complexes (2021) (1)
- La machinerie moléculaire de sécrétion des neurotransmetteurs (2015) (1)
- Myt1l haploinsufficiency leads to obesity and multifaceted behavioral alterations in mice (2022) (1)
- Engineered synaptic tools reveal localized cAMP signaling in synapse assembly (2021) (1)
- Teneurins assemble into presynaptic nanoclusters that promote synapse formation via postsynaptic non-teneurin ligands (2022) (1)
- Synaptic Vesicle Membrane Traffic and the Cycle of Rab3 (1993) (1)
- Instructions for the preparation of gene mapping reports (1995) (1)
- Persistent transcriptional programs are associated with remote memory in diverse cells of the medial prefrontal cortex (2019) (1)
- Rim1 and Rim2 Redundantly Determine Ca 2+ Channel Density and Readily-releasable Pool 2 Size at a Large Hindbrain Synapse 3 4 5 (2014) (1)
- An interview with the Kavli prize winners. Interview by Claudia Wiedemann. (2010) (1)
- Dissociating encoding of memory and salience by manipulating long-term synaptic potentiation (2022) (1)
- Analyses of the Autism-associated Neuroligin-3 R451C Mutation in Human Neurons Reveals a Gain-of-Function Synaptic Mechanism (2021) (1)
- Characteristics of Synaptic Vesicle Exocytosis (1999) (1)
- THE DYNAMIC INTERPLAY BETWEEN HOMEODOMAIN TRANSCRIPTION FACTORS AND CHROMATIN ENVIRONMENT REGULATES PRONEURAL FACTOR OUTCOMES (2020) (1)
- b-Neurexin Is a Ligand for the Staphylococcus aureus MSCRAMM (2009) (1)
- Neurexin IlIa: Extensive alternative splicing generates membrane-bound and soluble forms (2005) (1)
- A simple Ca2+-imaging approach to neural network analysis in cultured neurons (2020) (1)
- Vivo In Peptides in the CA1 Region of the Rat Hippocampus -Amyloid β Blockade of Long-Term Potentiation by (2015) (0)
- Engineered Adhesion Molecules Drive Synapse Organization (2022) (0)
- Interaction of recombinant soluble neuroligin-1 with neurexin-1-_ (2004) (0)
- Human Teneurin 2 extra-cellular region (2018) (0)
- Postsynaptic complexin controls AMPA receptor exocytosis during long term potentiation (2012) (0)
- Correction: ELKS1 localizes the synaptic vesicle priming protein bMunc13-2 to a specific subset of active zones (2017) (0)
- VAM3P N-TERMINAL DOMAIN SOLUTION STRUCTURE (2001) (0)
- Proteolytic regulation of calcium channels - avoiding controversy. (2022) (0)
- P1-183 Three-dimensional structure of an autonomously folded domain of human amyloid-β precursor protein (2004) (0)
- Author response: Latrophilin-2 and latrophilin-3 are redundantly essential for parallel-fiber synapse function in cerebellum (2020) (0)
- Solution structure of Rim2 Zinc Finger Domain (2005) (0)
- A combinatorial code of neurexin-3 alternative splicing controls inhibitory synapses via a trans-synaptic dystroglycan signaling loop (2022) (0)
- Munc 18-1 is essential for synaptic secretion by making synaptic vesicles fusion-ready (2001) (0)
- rat synaptotagmin 4 C2B domain in the presence of calcium (2004) (0)
- JCB_20160608603092017C 1..1 (2017) (0)
- Towards Understanding the Molecular Mechanism of Synchronous Neurotransmitter Release (2017) (0)
- Calsyntenin-3, an atypical cadherin, suppresses inhibitory basket- and stellate-cell synapses but boosts excitatory parallel-fiber synapses in cerebellum (2021) (0)
- Modeling for neurological diseases using human ES cell-derived neurons (2008) (0)
- Cell Stem Cell Generation of iN Cells from Liver 2 Cell (2011) (0)
- Crystal structure of the Neuroligin-1/Neurexin-1beta synaptic adhesion complex (2007) (0)
- Author response: Latrophilin GPCR signaling mediates synapse formation (2021) (0)
- CORRECTIONS (2007) (0)
- Neurexins and Company: towards a molecular logic of neural circuits (2015) (0)
- Neuroligin-3 confines AMPA receptors into nanoclusters, thereby controlling synaptic strength at the calyx of Held synapses (2022) (0)
- Intracellular Membrane Traffic (1999) (0)
- Pathomechanismen der auditorischen Neuropathie (2005) (0)
- The Molecular Logic Organizing the Functional Compartmentalization of Reciprocal Synapses (2021) (0)
- Cloning, Characterization, andExpression ofaNovelGDP Dissociation Inhibitor Isoform fromSkeletal Muscle (1994) (0)
- The RIM1alpha C2B domain (2007) (0)
- Synaptic vescicles and exocytosis (1994) (0)
- Identification of Endogenous/transfected Synaptic Proteins in Primary Neuronal Culture by a High-yield Immunogold Labeling (2003) (0)
- S1-01-04 APP intracellular domain (2004) (0)
- RIM1andRIM1AreSynthesizedfromDistinctPromoters oftheRIM1GenetoMediateDifferentialButOverlapping SynapticFunctions (2008) (0)
- Novel Neuron Types and Anatomical Organization of the Striatum Revealed by Single-Cell RNA-Seq. (2016) (0)
- Explorer Presenilins are essential for regulating neurotransmitter release (2016) (0)
- A conversation with Thomas Südhof. Interview by Ushma S. Neill. (2013) (0)
- Distinct Neurexin-Cerebellin Complexes Control AMPA- and NMDA-Receptor Responses in a Circuit-Dependent Manner (2022) (0)
- P-557: Synapsin as a potential new drug target for hypertension (2001) (0)
- Faculty Opinions recommendation of Crystal structure of the endosomal SNARE complex reveals common structural principles of all SNAREs. (2002) (0)
- Study on vitamin D supplementation seeks participants who are at risk for diabetes ten scholars receive Spectrum clinical research training awards (2013) (0)
- Structural basis for the evolutionary inactivation of Ca[superscript 2+] binding to synaptotagmin 4 (2010) (0)
- Proteins that Function in Synaptic Vesicle Exocytosis (1999) (0)
- Calelectrin, an Mr-32000 polypeptide, is associated with membranes and cytoskeleton in a calcium-dependent manner (1983) (0)
- THREE DIMENSIONAL STRUCTURE OF THE N-TERMINAL DOMAIN OF SYNTAXIN 1A (1998) (0)
- Direct induction of human neurons from fibroblasts carrying the neuropsychiatric 22q11.2 microdeletion reveals transcriptome- and epigenome-wide alterations (2021) (0)
- A role for Rab3a in the final stages of synaptic vesicle exocytosis. (1996) (0)
- Machinerie moléculaire de la libération des neurotransmetteurs (2014) (0)
- Molecular Mechanisms Controlling Neurotransmitter Release by the Primed SNARE-complexin-Synaptotagmin Complex (2018) (0)
- Table of Contents (1991) (0)
- Crystal structure of the C domain of synapsin Ia from bovine (1996) (0)
- Calmodulin Suppresses Synaptotagmin-2 Transcription in (2010) (0)
- Dynamin: Potential regulator of vesicle dynamics (1994) (0)
- Mechanism of Ca 2 +-Regulated Membrane Fusion (2011) (0)
- Backbone Assignments of folded alpha-synuclein (2003) (0)
- Analysis of neuroligin-3 knock-in mice relevant to autism spectrum disorders (2009) (0)
- Crystal structure of the extracellular esterase domain of Neuroligin-1 (2007) (0)
- As of today, 30 Nobel Laureates have endorsed the attached January 19, 2016, H.R. Network's Statement to the Government of Turkey regarding the plight of hundreds of Turkish academic colleagues. (2016) (0)
- Activity-dependent synapse validation by neurexin ligands, LRRTMs and neuroligins (2011) (0)
- Structures of C 1 q-like Pro teins Reveal Unique Features among the C 1 q / TNF Superfamily Graphical Abstract Highlights (2015) (0)
- Not All Embryonic Stem Cell Lines Are Created Equal (2007) (0)
- 1 Dynamic Synaptotagmin-1-SNARE Complex Binding Mode in Solution (2015) (0)
- The Autism Risk Factor CHD8 Is a Chromatin Activator in Human Neurons and Functionally Dependent on the ERK-MAPK Pathway Effector ELK1 (2021) (0)
- 134th Annual Meeting Works in Progress Abstracts (2009) (0)
- SOLUTION STRUCTURE OF THE CALCIUM-BOUND FIRST C2-DOMAIN OF SYNAPTOTAGMIN I (1998) (0)
- Solution structure of CAPPD*, an independently folded extracellular domain of human Amyloid-beta Precursor Protein (2004) (0)
- Three-dimensional structure of the calcium-free Piccolo C2A-domain (2004) (0)
- Role of Neurexins and Neuroligins in synapse development and maintenance (2016) (0)
- Crystal structure of the GAIN and HormR domains of brain angiogenesis inhibitor 3 (BAI3) (2012) (0)
- Purification of calelectrins. (1987) (0)
- Crystal structure of the GAIN and HormR domains of CIRL 1/Latrophilin 1 (CL1) (2012) (0)
- The Autism Risk Factor CHD8 Is a Chromatin Activator and Functionally Dependent on the ERK-MAPK Pathway Effector ELK1 (2020) (0)
- CB1 receptor activation rapidly alters synaptic vesicle numbers in mouse hippocampal synapses (2021) (0)
- Supplemental Data Nicastrin Functions as a γ-Secretase-Substrate Receptor (2005) (0)
- Deletion of Calsyntenin-3, an atypical cadherin, suppresses inhibitory synapses but increases excitatory parallel-fiber synapses in cerebellum (2022) (0)
- Characteristics and Proteins of Synaptic Vesicle Endocytosis (1999) (0)
- Elements regulateurs de sterol (1988) (0)
- QnAs with Thomas C. Südhof. Interview by Prashant Nair. (2010) (0)
- By sterols regulated promoter elements. (1988) (0)
- Endocytosis in the axon initial segment maintains neuronal polarity (2022) (0)
- Induction of synapse formation by de novo neurotransmitter synthesis (2022) (0)
- Why publish single observations? Because Science Matters. (2016) (0)
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