Thomas Cech

Q: What Schools Are Affiliated With Thomas Cech

Thomas Cech is affiliated with the following schools: Grinnell College, University of Liverpool, University of Colorado Boulder, University of California, Berkeley, Palacký University Olomouc, University of Colorado

Thomas Cech's AcademicInfluence.com Rankings

Thomas Cech

Chemistry

#72

World Rank

#177

Historical Rank

#33

USA Rank

chemistry Degrees

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Chemistry

Thomas Cech's Degrees

PhD Chemistry University of California, Berkeley

Why Is Thomas Cech Influential?

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According to Wikipedia, Thomas Robert Cech is an American chemist who shared the 1989 Nobel Prize in Chemistry with Sidney Altman, for their discovery of the catalytic properties of RNA. Cech discovered that RNA could itself cut strands of RNA, suggesting that life might have started as RNA. He found that RNA can not only transmit instructions, but also that it can speed up the necessary reactions.

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Thomas Cech's Published Works

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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Self-splicing RNA: Autoexcision and autocyclization of the ribosomal RNA intervening sequence of tetrahymena (1982) (1970)
The Noncoding RNA Revolution—Trashing Old Rules to Forge New Ones (2014) (1843)
Reverse transcriptase motifs in the catalytic subunit of telomerase. (1997) (1274)
Crystal Structure of a Group I Ribozyme Domain: Principles of RNA Packing (1996) (1199)
Telomerase catalytic subunit homologs from fission yeast and human. (1997) (1171)
Pot1, the Putative Telomere End-Binding Protein in Fission Yeast and Humans (2001) (1045)
Inhibition of telomerase by G-quartet DMA structures (1991) (999)
Monovalent cation-induced structure of telomeric DNA: The G-quartet model (1989) (988)
Self-splicing of group I introns. (1990) (783)
In vitro splicing of the ribosomal RNA precursor of tetrahymena: Involvement of a guanosine nucleotide in the excision of the intervening sequence (1981) (774)
The POT1–TPP1 telomere complex is a telomerase processivity factor (2007) (693)
The chemical repertoire of natural ribozymes (2002) (658)
Biological catalysis by RNA. (1986) (535)
Regulation of telomere length and function by a Myb-domain protein in fission yeast (1997) (513)
Structure of human POT1 bound to telomeric single-stranded DNA provides a model for chromosome end-protection (2004) (475)
RNA Duplex Map in Living Cells Reveals Higher-Order Transcriptome Structure (2016) (455)
The intervening sequence RNA of Tetrahymena is an enzyme. (1986) (434)
How do lncRNAs regulate transcription? (2017) (433)
Beginning to Understand the End of the Chromosome (2004) (433)
Biogeographical patterns and determinants of invasion by forest pathogens in Europe. (2013) (432)
Conserved sequences and structures of group I introns: building an active site for RNA catalysis--a review. (1988) (431)
The generality of self-splicing RNA: Relationship to nuclear mRNA splicing (1986) (421)
Promiscuous RNA binding by Polycomb Repressive Complex 2 (2013) (411)
The chemistry of self-splicing RNA and RNA enzymes. (1987) (406)
Telomerase and DNA end replication: no longer a lagging strand problem? (1995) (378)
Human POT1 disrupts telomeric G-quadruplexes allowing telomerase extension in vitro. (2005) (369)
Finding the end: recruitment of telomerase to telomeres (2013) (343)
RNA Tertiary Structure Mediation by Adenosine Platforms (1996) (332)
Defining the inside and outside of a catalytic RNA molecule. (1989) (327)
Visualizing the higher order folding of a catalytic RNA molecule. (1991) (318)
The Ribosome Is a Ribozyme (2000) (312)
The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity (2012) (310)
Reversing Time: Origin of Telomerase (1998) (310)
A preorganized active site in the crystal structure of the Tetrahymena ribozyme. (1998) (302)
Telomerase and the maintenance of chromosome ends. (1999) (297)
Peptide bond formation by in vitro selected ribozymes (1997) (292)
Two modes of survival of fission yeast without telomerase. (1998) (287)
Saccharomyces cerevisiae telomerase is an Sm small nuclear ribonucleoprotein particle (1999) (284)
Metal ion catalysis in the Tetrahymena ribozyme reaction (1993) (281)
Representation of the secondary and tertiary structure of group I introns (1994) (279)
Purification of telomerase from Euplotes aediculatus: requirement of a primer 3' overhang. (1996) (274)
Secondary structure of the circular form of the Tetrahymena rRNA intervening sequence: a technique for RNA structure analysis using chemical probes and reverse transcriptase. (1985) (262)
Three Ever Shorter Telomere (EST) genes are dispensable for in vitro yeast telomerase activity. (1997) (261)
RNA seeds higher-order assembly of FUS protein. (2013) (259)
TERT promoter mutations and telomerase reactivation in urothelial cancer (2015) (257)
Ribozyme-mediated repair of defective mRNA by targeted trans-splicing (1994) (252)
Nuclear proteins that bind the pre-mRNA 3' splice site sequence r(UUAG/G) and the human telomeric DNA sequence d(TTAGGG)n (1993) (249)
Autocatalytic cyclization of an excised intervening sequence RNA is a cleavage–ligation reaction (1983) (245)
Catalysis of RNA cleavage by the Tetrahymena thermophila ribozyme. 1. Kinetic description of the reaction of an RNA substrate complementary to the active site. (1990) (244)
Human telomerase: biogenesis, trafficking, recruitment, and activation (2015) (237)
Human POT1 Facilitates Telomere Elongation by Telomerase (2003) (235)
The recruitment of chromatin modifiers by long noncoding RNAs: lessons from PRC2 (2015) (234)
The β subunit of Oxytricha telomere-binding protein promotes G-quartet formation by telomeric DNA (1993) (233)
Yeast telomerase RNA: a flexible scaffold for protein subunits. (2004) (231)
Structure of the Tetrahymena ribozyme: base triple sandwich and metal ion at the active site. (2004) (229)
GAAA tetraloop and conserved bulge stabilize tertiary structure of a group I intron domain. (1994) (227)
Specific interaction between the self-splicing RNA of Tetrahymena and its guanosine substrate: implications for biological catalysis by RNA (1984) (227)
Sequence-specific endoribonuclease activity of the Tetrahymena ribozyme: enhanced cleavage of certain oligonucleotide substrates that form mismatched ribozyme-substrate complexes. (1988) (226)
Minor-groove recognition of double-stranded RNA by the double-stranded RNA-binding domain from the RNA-activated protein kinase PKR. (1996) (223)
A model for the RNA-catalyzed replication of RNA. (1986) (206)
An independently folding domain of RNA tertiary structure within the Tetrahymena ribozyme. (1993) (203)
DNA self-recognition in the structure of Pot1 bound to telomeric single-stranded DNA (2003) (202)
FUS binds the CTD of RNA polymerase II and regulates its phosphorylation at Ser2. (2012) (202)
Tethering ribozymes to a retroviral packaging signal for destruction of viral RNA. (1993) (198)
Telomerase RNAs of different ciliates have a common secondary structure and a permuted template. (1994) (194)
POT1–TPP1 enhances telomerase processivity by slowing primer dissociation and aiding translocation (2010) (193)
Switching Human Telomerase On and Off with hPOT1 Protein in Vitro* (2005) (192)
POT1 Stimulates RecQ Helicases WRN and BLM to Unwind Telomeric DNA Substrates* (2005) (191)
Aminoacyl esterase activity of the Tetrahymena ribozyme. (1992) (188)
Toward a consensus on the binding specificity and promiscuity of PRC2 for RNA. (2015) (188)
Secondary structure of the Tetrahymena ribosomal RNA intervening sequence: structural homology with fungal mitochondrial intervening sequences. (1983) (187)
Ribozyme-catalyzed and nonenzymatic reactions of phosphate diesters: rate effects upon substitution of sulfur for a nonbridging phosphoryl oxygen atom. (1991) (185)
The Tetrahymena ribozyme acts like an RNA restriction endonuclease (1986) (183)
RNA splicing: Three themes with variations (1983) (183)
Iron(II)-ethylenediaminetetraacetic acid catalyzed cleavage of RNA and DNA oligonucleotides: similar reactivity toward single- and double-stranded forms. (1990) (178)
The RNA worlds in context. (2012) (177)
Human Pot1 (Protection of Telomeres) Protein: Cytolocalization, Gene Structure, and Alternative Splicing (2002) (176)
Crystal structure of the essential N-terminal domain of telomerase reverse transcriptase (2006) (175)
Protection of telomeres by the Ku protein in fission yeast. (2000) (168)
Molecular analysis of PRC2 recruitment to DNA in chromatin and its inhibition by RNA (2017) (168)
Essential functions of amino-terminal domains in the yeast telomerase catalytic subunit revealed by selection for viable mutants. (1999) (167)
Mutation of the TERT promoter, switch to active chromatin, and monoallelic TERT expression in multiple cancers (2015) (164)
One binding site determines sequence specificity of Tetrahymena pre-rRNA self-splicing, trans-splicing, and RNA enzyme activity (1986) (164)
Photocrosslinking of 5-iodouracil-substituted RNA and DNA to proteins. (1993) (164)
Reverse self-splicing of the tetrahymena group I intron: Implication for the directionality of splicing and for intron transposition (1989) (162)
Analysis of the structure of Tetrahymena nuclear RNAs in vivo: telomerase RNA, the self-splicing rRNA intron, and U2 snRNA. (1995) (162)
RNA substrate binding site in the catalytic core of the Tetrahymena ribozyme (1992) (160)
RNA as an enzyme. (1986) (159)
Targeting of Polycomb Repressive Complex 2 to RNA by Short Repeats of Consecutive Guanines. (2017) (156)
A bulged stem tethers Est1p to telomerase RNA in budding yeast. (2002) (153)
Atomic level architecture of group I introns revealed. (2006) (152)
The intervening sequence of the ribosomal RNA precursor is converted to a circular RNA in isolated nuclei of tetrahymena (1981) (146)
A second catalytic metal ion in a group I ribozyme (1997) (145)
Cloning and expression of genes for the Oxytricha telomere-binding protein: Specific subunit interactions in the telomeric complex (1991) (141)
Ribozyme recognition of RNA by tertiary interactions with specific ribose 2′-OH groups (1991) (141)
Telomere shortening and loss of self-renewal in dyskeratosis congenita iPS cells (2011) (141)
Live Cell Imaging Reveals the Dynamics of Telomerase Recruitment to Telomeres (2016) (139)
Structural basis of the enhanced stability of a mutant ribozyme domain and a detailed view of RNA--solvent interactions. (2001) (138)
A labile phosphodiester bond at the ligation junction in a circular intervening sequence RNA. (1984) (137)
Biochemical Properties and Biological Functions of FET Proteins. (2015) (136)
New reactions of the ribosomal RNA precursor of Tetrahymena and the mechanism of self-splicing. (1986) (135)
Telomerase reverse transcriptase genes identified in Tetrahymena thermophila and Oxytricha trifallax. (1998) (133)
Functional interaction between telomere protein TPP1 and telomerase. (2010) (132)
Telomeric DNA-protein interactions of Oxytricha macronuclear DNA. (1987) (129)
Chromatin structure of the molecular ends of oxytricha macronuclear DNA: phased nucleosomes and a telomeric complex (1984) (125)
Triple-helix structure in telomerase RNA contributes to catalysis (2008) (125)
Low abundance of telomerase in yeast: implications for telomerase haploinsufficiency. (2006) (125)
Stereochemistry of RNA cleavage by the Tetrahymena ribozyme and evidence that the chemical step is not rate-limiting. (1989) (124)
RNA editing: World's smallest introns? (1991) (121)
Cross-linking of DNA with trimethylpsoralen is a probe for chromatin structure (1977) (121)
Metal ion requirements for sequence-specific endoribonuclease activity of the Tetrahymena ribozyme. (1989) (121)
Catalysis of RNA cleavage by the Tetrahymena thermophila ribozyme. 2. Kinetic description of the reaction of an RNA substrate that forms a mismatch at the active site. (1990) (121)
Telomerase and chromosome end maintenance. (1998) (121)
Telomerase RNA bound by protein motifs specific to telomerase reverse transcriptase. (2000) (120)
RNA worlds : from life's origins to diversity in gene regulation (2011) (119)
Essential Regions of Saccharomyces cerevisiae Telomerase RNA: Separate Elements for Est1p and Est2p Interaction (2002) (119)
Inventory of telomerase components in human cells reveals multiple subpopulations of hTR and hTERT (2014) (114)
Polyadenylation of telomerase RNA in budding yeast. (1997) (114)
Characterization of a G-quartet formation reaction promoted by the beta-subunit of the Oxytricha telomere-binding protein. (1993) (113)
Crawling Out of the RNA World (2009) (111)
Direct measurement of oligonucleotide substrate binding to wild-type and mutant ribozymes from Tetrahymena. (1990) (110)
Assembly of a Ribonucleoprotein Catalyst by Tertiary Structure Capture (1996) (106)
DNA cleavage catalysed by the ribozyme from Tetrahymena (1990) (106)
Self-splicing RNA: implications for evolution. (1985) (105)
Protein facilitation of group I intron splicing by assembly of the catalytic core and the 5′ splice site domain (1995) (104)
11 Structure and Mechanism of the Large Catalytic RNAs: Group I and Group II Introns and Ribonuclease P (1993) (103)
Binding of the protein kinase PKR to RNAs with secondary structure defects: role of the tandem A-G mismatch and noncontiguous helixes. (1998) (103)
The importance of being ribose at the cleavage site in the Tetrahymena ribozyme reaction. (1993) (100)
In vitro splicing of the ribosomal RNA precursor in nuclei of tetrahymena (1980) (100)
Ribozymes and their medical implications. (1988) (100)
Peptidyl-transferase ribozymes: trans reactions, structural characterization and ribosomal RNA-like features. (1998) (98)
Energetics and cooperativity of tertiary hydrogen bonds in RNA structure. (1999) (98)
Sharing Publication-Related Data and Materials: Responsibilities of Authorship in the Life Sciences1 (2003) (98)
RNA catalysis by a group I ribozyme. Developing a model for transition state stabilization. (1992) (97)
RNA as a flexible scaffold for proteins: yeast telomerase and beyond. (2006) (96)
Intermolecular exon ligation of the rRNA precursor of tetrahymena: Oligonucleotides can function as 5′ exons (1985) (95)
Fate of an intervening sequence ribonucleic acid: excision and cyclization of the Tetrahymena ribosomal ribonucleic acid intervening sequence in vivo. (1983) (94)
The anchor site of telomerase from Euplotes aediculatus revealed by photo-cross-linking to single- and double-stranded DNA primers (1997) (94)
A Mutant of Tetrahymena Telomerase Reverse Transcriptase with Increased Processivity* (2000) (93)
Cooperative binding of single-stranded telomeric DNA by the Pot1 protein of Schizosaccharomyces pombe. (2002) (92)
Contributions of 2'-hydroxyl groups of the RNA substrate to binding and catalysis by the Tetrahymena ribozyme. An energetic picture of an active site composed of RNA. (1993) (91)
Nucleic acid-binding specificity of human FUS protein (2015) (91)
Euplotes telomerase contains an La motif protein produced by apparent translational frameshifting (2000) (90)
Mutually Exclusive Binding of Telomerase RNA and DNA by Ku Alters Telomerase Recruitment Model (2012) (90)
Identification of human TERT elements necessary for telomerase recruitment to telomeres (2014) (90)
A miniature yeast telomerase RNA functions in vivo and reconstitutes activity in vitro (2005) (90)
Inhibition of telomerase RNA decay rescues telomerase deficiency caused by dyskerin or PARN defects (2016) (90)
Self-assembly of a group I intron active site from its component tertiary structural domains. (1995) (90)
Effect of monovalent cation-induced telomeric DNA structure on the binding of Oxytricha telomeric protein. (1990) (90)
Tertiary interactions with the internal guide sequence mediate docking of the P1 helix into the catalytic core of the Tetrahymena ribozyme. (1993) (88)
Movement of the guide sequence during RNA catalysis by a group I ribozyme. (1993) (87)
Activity and thermostability of the small self-splicing group I intron in the pre-tRNA(lle) of the purple bacterium Azoarcus. (1996) (87)
RNA as an RNA polymerase: net elongation of an RNA primer catalyzed by the Tetrahymena ribozyme. (1988) (87)
Properties of the telomeric DNA-binding protein from Oxytricha nova. (1989) (85)
Chromatin structure at the replication origins and transcription-initiation regions of the ribosomal RNA genes of tetrahymena (1984) (84)
A novel two-step genome editing strategy with CRISPR-Cas9 provides new insights into telomerase action and TERT gene expression (2015) (84)
The efficiency and versatility of catalytic RNA: implications for an RNA world. (1993) (84)
Mitochondrial telomeres: Surprising diversity of repeated telomeric DNA sequences among six species of Tetrahymena (1988) (80)
Three-dimensional model of the active site of the self-splicing rRNA precursor of Tetrahymena. (1987) (80)
Ribozyme inhibitors: deoxyguanosine and dideoxyguanosine are competitive inhibitors of self-splicing of the Tetrahymena ribosomal ribonucleic acid precursor. (1986) (80)
Two major tertiary folding transitions of the Tetrahymena catalytic RNA. (1994) (79)
Selection of an RNA molecule that mimics a major autoantigenic epitope of human insulin receptor. (1995) (79)
Shaping human telomeres: from shelterin and CST complexes to telomeric chromatin organization (2021) (79)
Multiple folding pathways for the P4-P6 RNA domain. (2000) (78)
Ribozymes, the first 20 years. (2001) (77)
Targeted CRISPR disruption reveals a role for RNase MRP RNA in human preribosomal RNA processing (2017) (77)
Many disease-associated variants of hTERT retain high telomerase enzymatic activity (2013) (76)
Modulation of telomerase activity by telomere DNA-binding proteins in Oxytricha. (1998) (76)
N-terminal domain of yeast telomerase reverse transcriptase: recruitment of Est3p to the telomerase complex. (2003) (75)
The telomeres of the linear mitochondrial DNA of tetrahymena thermophila consist of 53 bp tandem repeats (1986) (72)
The 2,6-diaminopurine riboside.5-methylisocytidine wobble base pair: an isoenergetic substitution for the study of G.U pairs in RNA. (1994) (72)
Conserved RNA-binding specificity of polycomb repressive complex 2 is achieved by dispersed amino acid patches in EZH2 (2017) (72)
The intervening sequence excised from the ribosomal RNA precursor of Tetrahymena contains a 5-terminal guanosine residue not encoded by the DNA. (1982) (72)
Guanosine binding to the Tetrahymena ribozyme: thermodynamic coupling with oligonucleotide binding. (1993) (71)
Alternative secondary structures in the 5' exon affect both forward and reverse self-splicing of the Tetrahymena intervening sequence RNA. (1991) (71)
DYNAMICS OF THERMAL MOTIONS WITHIN A LARGE CATALYTIC RNA INVESTIGATED BY CROSS-LINKING WITH THIOL-DISULFIDE INTERCHANGE (1997) (71)
Efficient protein-facilitated splicing of the yeast mitochondrial bI5 intron. (1995) (69)
Tertiary structure around the guanosine-binding site of the Tetrahymena ribozyme. (1992) (69)
Replication of the extrachromosomal ribosomal RNA genes of Tetrahymena thermophilia. (1981) (68)
Mutations in a nonconserved sequence of the Tetrahymena ribozyme increase activity and specificity (1991) (66)
Oxytricha telomere-binding protein: separable DNA-binding and dimerization domains of the alpha-subunit. (1993) (66)
How telomeric protein POT1 avoids RNA to achieve specificity for single-stranded DNA (2009) (65)
Role of conserved sequence elements 9L and 2 in self-splicing of the Tetrahymena ribosomal RNA precursor (1986) (65)
RNA tertiary folding monitored by fluorescence of covalently attached pyrene. (1999) (65)
The impact of invasive Phytophthora species on European forests. (2013) (65)
RNA is essential for PRC2 chromatin occupancy and function in human pluripotent stem cells (2020) (65)
The RNA accordion model for template positioning by telomerase RNA during telomeric DNA synthesis (2011) (64)
Kinetic pathway for folding of the Tetrahymena ribozyme revealed by three UV-inducible crosslinks. (1996) (63)
An RNA internal loop acts as a hinge to facilitate ribozyme folding and catalysis. (1997) (62)
Electron microscopy of DNA crosslinked with trimethylpsoralen: test of the secondary structure of eukaryotic inverted repeat sequences. (1976) (62)
SCIENCE AT LIBERAL ARTS COLLEGES : A BETTER EDUCATION ? (1999) (62)
Mutation in TERT separates processivity from anchor-site function (2008) (62)
Oxytricha telomere-binding protein: DNA-dependent dimerization of the alpha and beta subunits. (1993) (60)
The anticodon is the signal sequence for mitochondrial import of glutamine tRNA in Tetrahymena. (1996) (60)
Conflicts of Interest--Moving Beyond Disclosure (2001) (59)
Local RNA structural changes induced by crystallization are revealed by SHAPE. (2007) (59)
A hammerhead ribozyme allows synthesis of a new form of the Tetrahymena ribozyme homogeneous in length with a 3' end blocked for transesterification. (1991) (59)
Allele-Specific DNA Methylation and Its Interplay with Repressive Histone Marks at Promoter-Mutant TERT Genes. (2017) (58)
An electron microscopic study of mouse foldback DNA (1975) (58)
Telomeric protein-DNA point contacts identified by photo-cross-linking using 5-bromodeoxyuridine. (1994) (58)
The structure of human CST reveals a decameric assembly bound to telomeric DNA (2020) (58)
Live-cell imaging reveals the dynamics of PRC2 and recruitment to chromatin by SUZ12-associated subunits (2018) (58)
Reconstitution of human shelterin complexes reveals unexpected stoichiometry and dual pathways to enhance telomerase processivity (2017) (57)
A stem-loop of Tetrahymena telomerase RNA distant from the template potentiates RNA folding and telomerase activity. (2001) (57)
Two versions of the gene encoding the 41-kilodalton subunit of the telomere binding protein of Oxytricha nova. (1990) (56)
Quantifying the energetic interplay of RNA tertiary and secondary structure interactions. (1999) (56)
FUS is sequestered in nuclear aggregates in ALS patient fibroblasts (2014) (56)
Expression of a RecQ Helicase Homolog Affects Progression through Crisis in Fission Yeast Lacking Telomerase* (2005) (55)
Group I Ribozymes: Substrate Recognition, Catalytic Strategies, and Comparative Mechanistic Analysis (1996) (54)
A template-proximal RNA paired element contributes to Saccharomyces cerevisiae telomerase activity. (2003) (54)
The Euplotes La motif protein p43 has properties of a telomerase-specific subunit. (2003) (54)
Tetrahymena telomerase is active as a monomer. (2003) (53)
Analysis of telomerase catalytic subunit mutants in vivo and in vitro in Schizosaccharomycespombe. (2000) (53)
Sites of circularization of the Tetrahymena rRNA IVS are determined by sequence and influenced by position and secondary structure. (1985) (53)
Characterization of the most rapidly renaturing sequences in mouse main-band DNA. (1973) (53)
The conserved U.G pair in the 5' splice site duplex of a group I intron is required in the first but not the second step of self-splicing (1989) (52)
Sydowia polyspora associated with current season needle necrosis (CSNN) on true fir (Abies spp.). (2010) (52)
Localization of transcribed regions on extrachromosomal ribosomal RNA genes of Tetrahymena thermophila by R-loop mapping. (1979) (52)
Mitochondrial import of only one of three nuclear‐encoded glutamine tRNAs in Tetrahymena thermophila. (1996) (51)
Coaxially stacked RNA helices in the catalytic center of the Tetrahymena ribozyme. (1994) (51)
Multiple new cryptic pathogenic Phytophthora species from Fagaceae forests in Austria, Italy and Portugal (2017) (51)
Assembly and self-association of Oxytricha telomeric nucleoprotein complexes (1989) (51)
A conserved base pair within helix P4 of the Tetrahymena ribozyme helps to form the tertiary structure required for self‐splicing. (1989) (51)
An early transition state for folding of the P4-P6 RNA domain. (2001) (51)
Nurturing interdisciplinary research (2004) (50)
Reversibility of cyclization of the tetrahymena rRNA intervening sequence: implication for the mechanism of splice site choice (1985) (50)
A self-splicing group I intron in the nuclear pre-rRNA of the green alga, Ankistrodesmus stipitatus. (1991) (50)
Selection of circularization sites in a group I IVS RNA requires multiple alignments of an internal template-like sequence (1987) (49)
Alteration of substrate specificity for the endoribonucleolytic cleavage of RNA by the Tetrahymena ribozyme. (1989) (49)
Binding of the CBP2 protein to a yeast mitochondrial group I intron requires the catalytic core of the RNA. (1991) (49)
Multiple Yeast Genes, Including Paf1 Complex Genes, Affect Telomere Length via Telomerase RNA Abundance (2008) (47)
Alkaline gel electrophoresis of deoxyribonucleic acid photoreacted with trimethylpsoralen: rapid and sensitive detection of interstrand cross-links. (1981) (47)
Method for determining RNA 3' ends and application to human telomerase RNA. (1996) (47)
Inhibition of Telomerase Recruitment and Cancer Cell Death* (2013) (47)
Self-splicing of the group I intron from Anabaena pre-tRNA: requirement for base-pairing of the exons in the anticodon stem. (1993) (47)
dGTP-dependent processivity and possible template switching of euplotes telomerase. (1997) (46)
Regulation of histone methylation by automethylation of PRC2 (2018) (46)
An important RNA tertiary interaction of group I and group II introns is implicated in gram-positive RNase P RNAs. (1995) (46)
Replacement of the conserved G.U with a G-C pair at the cleavage site of the Tetrahymena ribozyme decreases binding, reactivity, and fidelity. (1994) (46)
Self-splicing and enzymatic activity of an intervening sequence RNA from Tetrahymena. (1990) (45)
The Tetrahymena intervening sequence ribonucleic acid enzyme is a phosphotransferase and an acid phosphatase. (1986) (45)
Joining the Two Domains of a Group I Ribozyme to Form the Catalytic Core (1997) (44)
An ultraviolet-inducible adenosine-adenosine cross-link reflects the catalytic structure of the Tetrahymena ribozyme. (1990) (44)
Coupling of Tetrahymena ribosomal RNA splicing to beta-galactosidase expression in Escherichia coli. (1985) (44)
The Tetrahymena ribozyme acts like an RNA restriction endonuclease (1987) (44)
The Chemistry of Self-Splicing RNA and RNA Enzymes (1987) (43)
Evolution of Tetrahymena ribozyme mutants with increased structural stability (2002) (43)
A dimeric state for PRC2 (2014) (43)
Euplotes telomerase: evidence for limited base-pairing during primer elongation and dGTP as an effector of translocation. (1998) (42)
Crystals by design: a strategy for crystallization of a ribozyme derived from the Tetrahymena group I intron. (1997) (42)
Molecular cloning of telomere-binding protein genes from Stylonychia mytilis. (1991) (42)
Synthesis and Characterization of an RNA Dinucleotide Containing a 3‘-S-Phosphorothiolate Linkage (1996) (42)
Sequence requirements for self-splicing of the Tetrahymena thermophila pre-ribosomal RNA. (1985) (42)
Toward predicting self-splicing and protein-facilitated splicing of group I introns. (2008) (42)
Rebalancing Teaching and Research (2003) (42)
Effects of divalent metal ions on individual steps of the Tetrahymena ribozyme reaction. (1997) (41)
Self-splicing and enzymatic activity of an intervening sequence RNA fromTetrahymena (1990) (41)
Reactions of the intervening sequence of the Tetrahymena ribosomal ribonucleic acid precursor: pH dependence of cyclization and site-specific hydrolysis. (1985) (41)
Visualization of a tertiary structural domain of the Tetrahymena group I intron by electron microscopy. (1994) (40)
Hammerhead nailed down (1994) (40)
Oxytricha telomeric nucleoprotein complexes reconstituted with synthetic DNA. (1989) (40)
Telomerase is a true reverse transcriptase. A review. (1997) (39)
Guanosine binding required for cyclization of the self-splicing intervening sequence ribonucleic acid from Tetrahymena thermophila. (1987) (39)
A positive entropy change for guanosine binding and for the chemical step in the Tetrahymena ribozyme reaction. (1995) (39)
Multiple POT1-TPP1 proteins coat and compact long telomeric single-stranded DNA. (2011) (39)
Soluble domains of telomerase reverse transcriptase identified by high‐throughput screening (2005) (39)
Determinants of the 3' splice site for self-splicing of the Tetrahymena pre-rRNA. (1988) (38)
In vitro selection of RNAs with increased tertiary structure stability. (1999) (38)
Conformational switches involved in orchestrating the successive steps of group I RNA splicing. (1996) (38)
A natural ribozyme with 3',5' RNA ligase activity. (2009) (37)
Global expression changes resulting from loss of telomeric DNA in fission yeast (2004) (37)
Exocyclic amine of the conserved G.U pair at the cleavage site of the Tetrahymena ribozyme contributes to 5'-splice site selection and transition state stabilization. (1996) (37)
Identification of ribozymes within a ribozyme library that efficiently cleave a long substrate RNA. (1995) (37)
Thermodynamic stability of the P4-P6 domain RNA tertiary structure measured by temperature gradient gel electrophoresis. (1998) (36)
13 Building a Catalytic Active Site Using Only RNA (1999) (36)
Structures involved in Tetrahymena rRNA self-splicing and RNA enzyme activity. (1987) (36)
Telomerase RNA localized in the replication band and spherical subnuclear organelles in hypotrichous ciliates (1995) (36)
G-strings at chromosome ends (1988) (36)
Chromatin structure of the ribosomal RNA genes of Tetrahymena thermophila as analyzed by trimethylpsoralen crosslinking in vivo. (1980) (36)
Self‐splicing of the Tetrahymena intron from mRNA in mammalian cells (1999) (35)
Ku can contribute to telomere lengthening in yeast at multiple positions in the telomerase RNP. (2011) (35)
DNA-induced dimerization of the single-stranded DNA binding telomeric protein Pot1 from Schizosaccharomyces pombe (2011) (34)
Ribozyme self-replication? (1989) (34)
Tetrahymena Telomerase Protein p65 Induces Conformational Changes throughout Telomerase RNA (TER) and Rescues Telomerase Reverse Transcriptase and TER Assembly Mutants (2010) (34)
Fostering innovation and discovery in biomedical research. (2005) (34)
Organization of highly repeated sequences in mouse main-band DNA. (1976) (34)
3′ terminal diversity of MRP RNA and other human noncoding RNAs revealed by deep sequencing (2013) (33)
Folding of group I introns from bacteriophage T4 involves internalization of the catalytic core. (1991) (33)
Mutagenesis and comparative sequence analysis of a base triple joining the two domains of group I ribozymes. (1997) (33)
Catalysis of RNA cleavage by a ribozyme derived from the group I intron of Anabaena pre-tRNA(Leu). (1994) (33)
The Euplotes telomerase subunit p43 stimulates enzymatic activity and processivity in vitro. (2004) (32)
Translocation of an RNA duplex on a ribozyme (1994) (32)
Self‐Splicing and Enzymatic Activity of an Intervening Sequence RNA from Tetrahymena (1990) (31)
From leaf to continent: The multi-scale distribution of an invasive cryptic pathogen complex on oak (2018) (31)
Relative orientation of RNA helices in a group 1 ribozyme determined by helix extension electron microscopy. (1995) (31)
Oligomerization of intervening sequence RNA molecules in the absence of proteins. (1985) (31)
Deletion of nonconserved helices near the 3' end of the rRNA intron of Tetrahymena thermophila alters self-splicing but not core catalytic activity. (1988) (30)
5' exon requirement for self-splicing of the Tetrahymena thermophila pre-ribosomal RNA and identification of a cryptic 5' splice site in the 3' exon. (1987) (30)
DNA-protein interactions in the Drosophila melanogaster mitochondrial genome as deduced from trimethylpsoralen crosslinking patterns. (1980) (30)
Disease mutant analysis identifies a new function of DAXX in telomerase regulation and telomere maintenance (2015) (29)
Electron microscopy of DNA cross-linked with trimethylpsoralen: a probe for chromatin structure. (1977) (29)
Evolution of biological catalysis: ribozyme to RNP enzyme. (2009) (29)
Inhibition of yeast telomerase action by the telomeric ssDNA-binding protein, Cdc13p (2008) (29)
Contributions of the TEL-patch amino acid cluster on TPP1 to telomeric DNA synthesis by human telomerase. (2015) (28)
In vivo selection of better self-splicing introns in Escherichia coli: the role of the P1 extension helix of the Tetrahymena intron. (2002) (27)
Competition between PRC2.1 and 2.2 subcomplexes regulates PRC2 chromatin occupancy in human stem cells. (2020) (26)
Mechanism of recognition of the 5′ splice site in self-splicing group I introns (1986) (26)
Catalytic RNA: structure and mechanism. (1993) (26)
RNA recognition by the DNA end-binding Ku heterodimer. (2013) (26)
Chromosome end games. (1994) (25)
A tertiary interaction in the Tetrahymena intron contributes to selection of the 5' splice site. (1994) (25)
Self-catalyzed cyclization of the intervening sequence RNA of Tetrahymena: inhibition by methidiumpropyl.EDTA and localization of the major dye binding sites. (1985) (24)
Different nucleosome spacing in transcribed and non-transcribed regions of the ribosomal RNA gene in Tetrahymena thermophila. (1983) (24)
Yeast telomerase is specialized for C/A-rich RNA templates. (2003) (24)
Structure and function of steroid receptor RNA activator protein, the proposed partner of SRA noncoding RNA. (2014) (24)
RNA finds a simpler way (2004) (24)
Telomerase and the chromosome end replication problem. (1997) (24)
Dynamics of human telomerase recruitment depend on template-telomere base pairing (2018) (23)
Single-cell imaging reveals unexpected heterogeneity of telomerase reverse transcriptase expression across human cancer cell lines (2019) (23)
X-ray crystallography of large RNAs: heavy-atom derivatives by RNA engineering. (1996) (23)
Ribozyme engineering (1992) (22)
Polycomb-mediated genome architecture enables long-range spreading of H3K27 methylation (2020) (22)
Effects of nucleotide analogues on Euplotes aediculatus telomerase processivity: evidence for product-assisted translocation. (2002) (22)
Kinetic and secondary structure analysis of Naegleria andersoni GIR1, a group I ribozyme whose putative biological function is site-specific hydrolysis. (1997) (22)
Self-catalyzed cyclization of the intervening sequence RNA of Tetrahymena: inhibition by intercalating dyes. (1985) (21)
Self-Splicing and Enzymatic Activity of an Intervening Sequence RNA from Tetrahymena (1990) (20)
The Biomedical Research Bottleneck (2001) (20)
Chromatin structure in living cells. (1978) (19)
Metal-Ion Dependence of Active-Site Structure of the Tetrahymena Ribozyme Revealed by Site-Specific Photo-Cross-Linking (1994) (19)
Self-splicing and enzymatic cleavage of RNA by a group I intervening sequence. (1990) (19)
Sequence-specific and 3'-end selective single-strand DNA binding by the Oxytricha nova telomere end binding protein alpha subunit. (2003) (18)
C9orf72 and triplet repeat disorder RNAs: G-quadruplex formation, binding to PRC2 and implications for disease mechanisms (2019) (18)
Mutations in the Tetrahymena ribozyme internal guide sequence: effects on docking of the P1 helix into the catalytic core and correlation with catalytic activity. (1996) (17)
Phylogenetic relationships and altered genome structures among Tetrahymenamitochondrial DNAs (1988) (17)
Mesenchymal and MAPK Expression Signatures Associate with Telomerase Promoter Mutations in Multiple Cancers (2020) (16)
Nuclear compartmentalization of TERT mRNA and TUG1 lncRNA is driven by intron retention (2021) (16)
Allele‐specific proximal promoter hypomethylation of the telomerase reverse transcriptase gene (TERT) associates with TERT expression in multiple cancers (2020) (16)
Doing More for Kate (2005) (15)
Characterization of the rapidly renaturing sequences in the main CsCl density bands of Drosophila, mouse, and human DNA. (1974) (15)
Mutations at the guanosine-binding site of the Tetrahymena ribozyme also affect site-specific hydrolysis. (1992) (15)
Phosphorylation of the Oxytricha telomere protein: possible cell cycle regulation. (1995) (14)
In vitro selection of the Naegleria GIR1 ribozyme identifies three base changes that dramatically improve activity. (1998) (14)
DNA-protein interactions in the Drosophila virilis mitochondrial chromosome. (1984) (13)
Comparison of crystal structure interactions and thermodynamics for stabilizing mutations in the Tetrahymena ribozyme. (2006) (13)
TRIM28 is a transcriptional activator of the mutant TERT promoter in human bladder cancer (2021) (13)
The Harvey lectures, Series 82 (1988) (12)
CST does not evict elongating telomerase but prevents initiation by ssDNA binding (2021) (12)
RNA World research—still evolving (2015) (12)
Reconstitution of a telomeric replicon organized by CST (2021) (11)
Telomeric repeats of Tetrahymena malaccensis mitochondrial DNA: a multimodal distribution that fluctuates erratically during growth. (1988) (11)
RNase P branches out from RNP to protein: organelle-triggered diversification? (2012) (11)
Fishing for fresh catalysts (1993) (10)
Selecting apt RNAs for NMR. (1996) (10)
Phylogenetic relationships and altered genome structures among Tetrahymena mitochondrial DNAs. (1988) (10)
Telomerase in bladder cancer: back to a better future? (2014) (10)
Transcribed and non-transcribed regions of Tetrahymena ribosomal gene chromatin have different accessibilities to micrococcal nuclease. (1983) (10)
Bending and looping of long DNA by Polycomb repressive complex 2 revealed by AFM imaging in liquid. (2020) (9)
In Crystallo Selection to Establish New RNA Crystal Contacts. (2018) (9)
Conserved thermochemistry of guanosine nucleophile binding for structurally distinct group I ribozymes. (1996) (8)
A quantitative study of the flexibility contributed to RNA structures by nicks and single-stranded gaps. (1998) (8)
RNA chemistry. Ribozyme self-replication? (1989) (8)
Academia and industry: Companies on campus (2014) (8)
4 Telomere Proteins (1995) (7)
Translational Careers (2009) (7)
8 – Ribosomal RNA Gene Expression in Tetrahymena: Transcription and RNA Splicing (1986) (7)
Science and business. Conflicts of interest--moving beyond disclosure. (2001) (7)
Crystal structure of human POT1 bound to telomeric single-stranded DNA (TTAGGGTTAG) (2004) (7)
Engineering cis-telomerase RNAs that add telomeric repeats to themselves (2010) (6)
Fission yeast telosomes: non-canonical histone-containing chromatin structures dependent on shelterin and RNA (2018) (6)
Group I Introns: New Molecular Mechanisms for mRNA Repair (1995) (6)
Ribozymes. Hammerhead nailed down. (1994) (5)
Telomeric protein-DNA point contacts identified by photo-crosslinking using 5-bromodeoxyuridine. [Erratum to document cited in CA120:186170] (1994) (5)
erratum: Saccharomyces cerevisiae telomerase is an Sm small nuclear ribonucleoprotein particle (1999) (5)
Cryphonectria carpinicola sp. nov. Associated with hornbeam decline in Europe. (2021) (5)
Education for Entrepreneurship – A Challenge for School Practice (2017) (5)
Managing Your Own Lab (2004) (5)
Not just Salk (2017) (5)
A Tetrahymena intron nucleotide connected to the GTP/arginine site. (1989) (5)
SnapShot: Telomeres and Telomerase (2012) (5)
The RNAWorlds in Context (2012) (4)
How a chemist looks at RNA. (2013) (4)
The intervening sequence RNA of Tetrahymena is an enzyme. 1986. (1992) (4)
A dimeric state for PRC 2 (2014) (4)
Allele-Specific DNA Methylation and Its Interplay with Repressive Histone Marks at Promoter-Mutant TERT Genes. (2020) (3)
Human Pot 1 ( Protection of Telomeres ) Protein : Cytolocalization , Gene Structure , and Alternative Splicing (2019) (3)
Mobbing in primary schools: effects on interpersonalrelationships and school climate, options for protection andprevention (2010) (3)
Protein-RNA interaction restricts telomerase from running through the stop sign (2015) (3)
Engineering Disulfide Cross‐Links in RNA Using Thiol‐Disulfide Interchange Chemistry (2000) (3)
Ribozyme mechanisms and folding (2002) (3)
Oxytricha telomere-binding protein: DNA-dependent dimerization (2005) (2)
Self-splicing RNA and an RNA enzyme in Tetrahymena. (1987) (2)
Damage to stems, branches and twigs of broadleaf woody plants (2017) (2)
RNA in biological condensates (2021) (2)
Partial denaturation of mouse DNA in preparative CsCl density gradients at alkaline pH. (1976) (2)
A study of DNA denaturation in the ultracentrifuge (1976) (2)
Enhanced: The Ribosome Is a Ribozyme (2003) (2)
Dynamics of human telomerase recruitment depend on template-telomere base-pairing (2017) (2)
Publisher Correction: Shaping human telomeres: from shelterin and CST complexes to telomeric chromatin organization (2021) (2)
Widespread Phytophthora infestations of nursery stock in Central Europe as major pathway of Phytophthora diseases of forests and semi-natural ecosystems (2008) (2)
Fungi found in Norway and Austria in association with Abies-needles developing current season needle necrosis (CSNN) (2007) (2)
Winter 1-1-2003 N-terminal Domain of Yeast Telomerase Reverse Transcriptase : Recruitment of Est 3 p to the Telomerase Complex (2015) (2)
On the occasion of the 25th anniversary of the discovery of catalytic RNA (2007) (2)
Targeted mutagenesis in human iPSCs using CRISPR genome-editing tools. (2021) (2)
Causes of bullying in the workplace among primary school teachers of your paper (2018) (2)
The (noncoding) RNA world. (2013) (2)
THE IMPACT OF WORKPLACE BULLYING ON SELF-ESTEEM AMONG ELEMENTARY SCHOOL TEACHERS (2018) (1)
Conformational Dynamics Involved in RNA Self-Splicing (1986) (1)
PREPARATION OF CHILDREN TO LEAVE INSTITUTIONAL CARE AS A MEANS OF SUCCESSFUL SOCIAL INTEGRATION (2018) (1)
A Lifelong Passion for All Things Ribonucleic (2018) (1)
3 – Multiple Enzymatic Activities of an Intervening Sequence RNA from Tetrahymena (1987) (1)
Job satisfaction and risk of burnout in special needs nursery school teachers (2021) (1)
RELATIONSHIP BETWEEN CONFORMITY AND RISK BEHAVIOR IN CHILDREN IN EMERGING ADOLESCENCE (2021) (1)
Author response: Identification of human TERT elements necessary for telomerase recruitment to telomeres (2014) (1)
Specificity for 3′,5′-linked substrates in RNA-catalyzed RNA polymerization (1989) (1)
Vision of the role of social pedagogue in making schoolhealthier (2007) (1)
THE INCIDENCE OF BURNOUT SYNDROME RELATED TO JOB SATISFACTION AMONG KINDERGARTEN TEACHERS IN THE CZECH REPUBLIC (2020) (1)
Addendum: Crystal structure of the essential N-terminal domain of telomerase reverse transcriptase (2007) (1)
The effect of coping strategies on workplace bullying in elementary school teachers (2019) (1)
A Celebration of Life in the Trenches (1998) (1)
PREPARING INDIVIDUALS TO LEAVE THE CHILDREN’S HOME AND THEIR SUBSEQUENT INTEGRATION IN SOCIETY – OUTPUTS OF THE QUANTITATIVE PART OF THE RESEARCH SURVEY (2018) (1)
Life at the End of the Chromosome: Telomeres and Telomerase (2000) (1)
Damage to foliage of coniferous woody plants. (2017) (1)
Catalytic subunit of human telomerase (1997) (1)
Ribozyme-Catalyzed and Nonenzymatic Reactions of Phosphate Effects upon Substitution of Sulfur for a Nonbridging Phosphoryl (1991) (1)
DNMT1 inhibition by pUG-fold quadruplex RNA (2022) (1)
THE PERCEPTION OF SCHOOL CLIMATE BY WORKPLACE BULLYING VICTIMS AND BYSTANDERS (2018) (1)
Mechanism of self-splicing of the ribosomai RNA precursor of tetrahymena (1984) (1)
THE RELATIONSHIP BETWEEN COPING STRATEGIES AND SCHOOL CLIMATE PERCEPTION AMONG SECONDARY SCHOOL TEACHERS (2019) (1)
Nuclear compartmentalization of TERT mRNA and TUG1 lncRNA transcripts is driven by intron retention: implications for RNA-directed therapies (2020) (1)
The cryo-EM structure of human CST reveals a two-megadalton decameric assembly bound to telomeric DNA (2019) (1)
SELF-SPLICING AND ENZYMATIC ACTIVITY OF AN INTERVENING SEQUENCE RNA FROM T E T R A H Y M E N A (0)
Crystal Structure of hPOT1V2-GGTTAGGGTTAG (2010) (0)
United States Patent 19 Cech et al . ( 54 RNA RIBOZYME (2017) (0)
Structural basis for inactivation of PRC2 by G-quadruplex RNA (2023) (0)
Abstracts of papers presented at the 1987 Meeting on RNA Processing, May 13-May 17, 1987 (1987) (0)
Libraries 8-1-2014 A dimeric state for PRC 2 (2018) (0)
Conditions for drug primary prevention in Czech schools (2008) (0)
Corrigendum: A miniature yeast telomerase RNA functions in vivo and reconstitutes activity in vitro (2006) (0)
Shaping human telomeres: from shelterin and CST complexes to telomeric chromatin organization (2021) (0)
A novel two-step genome editing strategy with CRISPR-Cas9 provides new insights into telomerase action and TERT gene expression (2015) (0)
Molecular biology of RNA : proceedings of a Director's Sponsors-UCLA Symposium, held at Keystone, Colorado, April 4-10, 1988 (1989) (0)
Between the ‘RNA World’ and the ‘Protein World’ (1995) (0)
Tetrahymena pre-rRNA . Determinants of the 3 ' splice site for self-splicing of the References (2007) (0)
THE PREVALENCE OF MOBBING AMONG NURSERY SCHOOL TEACHERS (2021) (0)
Crystal Structure of the TEN domain of the Telomerase Reverse Transcriptase (2006) (0)
Telomeric repeats of Tetrahymena malaccensis mitochondrial DNA: a multimodal distribution that fluctuates erratically during growth (1988) (0)
11 The RNP World (2006) (0)
13a Catalytic Active Site (1999) (0)
HHMI's Attention to Wiley's Lab Staff (2002) (0)
Elementary school teachers awareness of mobbing and their experience from the environment of Czech schools (2009) (0)
Protein and polynucleoti nucleic acid compounds encoding catalytic subunit of human telomerase subunit, production and applications (1997) (0)
Human CST assembles into a decameric supercomplex upon binding to single-stranded telomeric DNA (2022) (0)
Comment: Strategies for nurturing science's next generation (2009) (0)
Reverve splicing of the Tetrahymana group I intron : studies in RNA catalysis (1990) (0)
INTRODUCTION TO MODELLING OF AN INTACT BIOLOGICAL CELL: STRUCTURAL BIOLOGY, FLUORESCENCE MICROSCOPY AND COMPUTATIONAL METHODS (2021) (0)
Secondary structure of the circular intervening sequence: A technique using chemical probes and reverse (RNA splicing/RNA catalysis/base modification/base methylation/R) (2016) (0)
SESSION 6: COMPUTERS IN INTERACTIVE STRUCTURAL BIOLOGY LEADING TO MODELLING OF AN INTACT BIOLOGICAL CELL (2021) (0)
Rns-ribozyme restriktionsendoribonukleasen and procedures. (1987) (0)
How do Phytophthora spp. harm woody plants (2012) (0)
In vivo Selection of Better Self-Splicing Introns in E . coli : the Role of the P 1 Extension Helix of the Tetrahymena Intron (2015) (0)
Crystal Structure of hPOT1V2-dTrUd(AGGGTTAG) (2010) (0)
Regulation of Monoallelic TERT Expression in Cancer Cells with Wildtype Promoters (2018) (0)
N-terminal Domain of Yeast Telomerase Reverse Transcriptase: Recruitment of Est3p to the Telomerase Complex □D (0)
Publisher Correction: Shaping human telomeres: from shelterin and CST complexes to telomeric chromatin organization (2021) (0)
A Study of DNA Denaturation in the U 1 t racent rif uge (2003) (0)
RNA is essential for PRC2 chromatin occupancy and function in human pluripotent stem cells (2020) (0)
Single-cell imaging reveals unexpected heterogeneity of TERT expression across cancer cell lines (2019) (0)
CRYSTAL STRUCTURE ANALYSIS OF A MUTANT P4-P6 DOMAIN (DELC209) OF TETRAHYMENA THEMOPHILA GROUP I INTRON. (2001) (0)
RELATIONSHIP BETWEEN WORKPLACE BULLYING, SELF-ESTEEM AND SCHOOL CLIMATE IN HEADMASTERS OF PRIMARY SCHOOLS (2019) (0)
SCHOOL CLIMATE AND ITS PERCEPTION BY SECONDARY SCHOOL TEACHERS IN RELATION TO COPING STRATEGIES (2020) (0)
A comparison of views of children and foster parents on theintegration of a child into a family (2013) (0)
Human steroid receptor RNA activator protein carboxy-terminal domain (2014) (0)
The complexity of transferring genetic information. (2023) (0)
SCHOOL PREVENTION METHODOLOGISTS AND THEIR WORK WITH STUDENTS DURING DISTANCE EDUCATION (2022) (0)
Response to HHMI from Mike Rossner (Executive Director, The Rockefeller University Press) and Ira Mellman (Editor in Chief, the Journal of Cell Biology): (2007) (0)
Response from Mike Rossner (Executive Director, The Rockefeller University Press) and Ira Mellman (Editor in Chief, The Journal of Cell Biology): (2007) (0)
A reply from HHMI (2007) (0)
Folding ofgroupIintrons frombacteriophage T4involves internalization ofthecatalytic core (1991) (0)
Solvency II and its Implications for Asian Insurance Markets (2013) (0)
[Oak decline in Upper Austria - development, reasons, contrameasures]. [German] (1987) (0)
A reply from Howard Hughes Medical Institute (HHMI). (2007) (0)
The role of social pedagogues in the school environment – a topic for discussion (2022) (0)
THE EFFECT OF MOBILE PHONE BAN IN SCHOOLS ON THE EVALUATION OF CLASSROOM CLIMATE (2020) (0)
Climate Assessment nad Experience with Mobbing among Public Administration Staff (Example from Czech Tax Office) (2020) (0)
Preface/Front Matter (1993) (0)
THE RELATIONSHIP BETWEEN COPING STRATEGIES AND WORKPLACE BULLYING IN ELEMENTARY SCHOOL TEACHERS (2018) (0)
THE RELATION OF SELF-ESTEEM ON RISK BEHAVIOUR AMONG EMERGING ADOLESCENTS (2020) (0)
THE PERCEPTION OF SCHOOL CLIMATE BY ELEMENTARY SCHOOL HEADMASTERS (2020) (0)
Historical Perspective by Aspinall Recipients : W.D. Farr, J.R. Fetcher & J. Sayre (2007) (0)
Learning by experience in the context of child development inleisure in the Czech Republic (2014) (0)
DEVELOPMENT OF RISKY BEHAVIOR OF PUPILS AND ITS PREVENTION AT CZECH PRIMARY SCHOOLS DURING THE COVID-19 PANDEMIC AND DISTANCE LEARNING (2022) (0)
A Reply from HHMI (2007) (0)
Preparing individuals to leave the institutional care from the perspective of the directors of the children's homes (2021) (0)
AWARENESS OF LOBBING AND THEIR EXPERIENCE FROM THE ENVIRONMENT OF CZECH SCHOOLS Tomáš Č ECH (2009) (0)
Leisure Education (English special issue of Educational Orientation) (2017) (0)
Prevention of Social and Pathological Symptoms with the Help ofLeisure Time (2009) (0)
THE EXPERIENCE OF IMPLEMENTATION OF PRIMARY PREVENTION OF RISK BEHAVIOUR IN NURSERY SCHOOLS (2021) (0)
Primary school teachers as implementers of anti-drug education (2004) (0)
SCHOOL CLIMATE AND OTHER FACTORS INFLUENCING THE RISK OF BURNOUT IN NURSERY SCHOOL TEACHERS (2021) (0)
Mobbing in primary schools and negative impact on school climate in the Czech Republic (2010) (0)
Mobbing at Primary Schools as an Ethic Problem (2010) (0)
Meeting a fork in the road: an interview with Tom Cech. Interview by Jane Gitschier. (2005) (0)
Competency of primary school teachers for the primary prevention of drug abuse with a view of the attitudes towards the topics of drug abuse prevention (2010) (0)
SPECIAL NEEDS TEACHERS AND THEIR PERSPECTIVE OF INCLUSIVE EDUCATION (2022) (0)
Transgenerational transfer of Czech folk culture among fellowcountrymen abroad (2009) (0)
PRC2 direct transfer from G-quadruplex RNA to dsDNA: Implications for RNA-binding chromatin modifiers (2022) (0)
Reconstitution of human shelterin complexes reveals unexpected stoichiometry and dual pathways to enhance telomerase processivity (2017) (0)
Mechanism of self splicing of the ribosomal rna precursor of tetrahymena thermophila (1985) (0)
Through the Glass Lightly (1995) (0)
Book Review Elizabeth Blackburn and the Story of Telomeres: Deciphering the Ends of DNA By Catherine Brady. 392 pp., illustrated. Cambridge, MA, MIT Press, 2007. $29.95. 978-0-262-02622-2 (2007) (0)
PHOSPHATE RECOGNITION BY A RIBOZYME (1992) (0)
Secondary structure oftheTetrahymena ribosomal RNA intervening sequence: Structural homology withfungal mitochondrial intervening sequences (RNAsplicing/free energy ofRNAfolding/computer prediction ofRNAstructure/maturase) (1983) (0)
TERT Promoter Mutations and Cancer (2016) (0)
Damage to leaves of broadleaf woody plants. (2017) (0)
Crystal structure of an essential telomerase‐specific domain of TERT (2006) (0)
Segmentation a site specifique d'adn monocatenaire (1991) (0)
Winter 2-20-2009 Crawling Out of the RNA World (2018) (0)
Crystal structure of human TPP1 (2006) (0)
DNA cleavage catalysed by the ribozyme from Tetrahymena (1990) (0)
Crystal structure of Pot1 (protection of telomere)- ssDNA complex (2003) (0)
Publisher Correction: Nuclear compartmentalization of TERT mRNA and TUG1 lncRNA is driven by intron retention (2021) (0)
Always a Teacher, Always a Student (2006) (0)
Oxytricha telomere-bindin p.rotei.n: . separable DNA-binding anommerlzauon domains of the -subunit (1993) (0)
Metallic human telomerase catalytic subunit (1997) (0)
Symposium 3: Non-enzymatic biocatalysts in nature and biotechnology (1990) (0)
Reversing Time : Minireview Origin of Telomerase (1998) (0)
Current requirements for change of primary drug prevention atelementary schools and education and training of teachers (2006) (0)
Cancer Cell Death Inhibition of Telomerase Recruitment and DNA and Chromosomes (2013) (0)
Author response: Conserved RNA-binding specificity of polycomb repressive complex 2 is achieved by dispersed amino acid patches in EZH2 (2017) (0)
50 years of the Czech Pedagogical Society (2013) (0)
Cryo-EM structure of CST bound to telomeric single-stranded DNA (2020) (0)
Reconstitution of a telomeric replicon organized by CST (2022) (0)
The Discovery of Ribonuclease P and Enzymatic Activity of Its RNA Subunit (2019) (0)
Cech single-and double-stranded DNA primers . aediculatus revealed by photo-cross-linking to The anchor site of telomerase from Euplotes (1996) (0)
high-throughput screening Soluble domains of telomerase reverse transcriptase identified (2005) (0)
New species of Neonectria as a cause of cankers on true firs (Abies spp.) in Scandinavia. (2012) (0)

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