Thomas D. Schmittgen

Thomas D. Schmittgen's AcademicInfluence.com Rankings

Chemistry

#885

World Rank

#1447

Historical Rank

Nanotechnology

#25

World Rank

#25

Historical Rank

chemistry Degrees

Download Badge

Chemistry

Thomas D. Schmittgen's Degrees

PhD Pharmaceutical Sciences University of California, San Francisco
Bachelors Pharmacy University of California, San Francisco

Why Is Thomas D. Schmittgen Influential?

(Suggest an Edit or Addition)

(See a Problem?)

Thomas D. Schmittgen's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. (2001) (134016)
Analyzing real-time PCR data by the comparative CT method (2008) (20184)
Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2 2 DD C T Method (17133)
Real-time quantitative PCR. (2001) (2779)
Detection of microRNA Expression in Human Peripheral Blood Microvesicles (2008) (1413)
Effect of experimental treatment on housekeeping gene expression: validation by real-time, quantitative RT-PCR. (2000) (1266)
Quantitative reverse transcription-polymerase chain reaction to study mRNA decay: comparison of endpoint and real-time methods. (2000) (1024)
Involvement of human micro-RNA in growth and response to chemotherapy in human cholangiocarcinoma cell lines. (2006) (1002)
Expression profiling identifies microRNA signature in pancreatic cancer (2006) (944)
Ultraconserved regions encoding ncRNAs are altered in human leukemias and carcinomas. (2007) (734)
MicroRNA-34a inhibits glioblastoma growth by targeting multiple oncogenes. (2009) (608)
Real-time PCR quantification of precursor and mature microRNA. (2008) (565)
Association of MicroRNA Expression in Hepatocellular Carcinomas with Hepatitis Infection, Cirrhosis, and Patient Survival (2008) (537)
Real-time expression profiling of microRNA precursors in human cancer cell lines (2005) (525)
A high-throughput method to monitor the expression of microRNA precursors. (2004) (462)
Methylation mediated silencing of MicroRNA-1 gene and its role in hepatocellular carcinogenesis. (2008) (458)
Systematic evaluation of microRNA processing patterns in tissues, cell lines, and tumors. (2007) (401)
MicroRNAs modulate the chemosensitivity of tumor cells (2008) (360)
Role of microRNA‐155 at early stages of hepatocarcinogenesis induced by choline‐deficient and amino acid–defined diet in C57BL/6 mice (2009) (289)
Antisense Inhibition of microRNA-21 or -221 Arrests Cell Cycle, Induces Apoptosis, and Sensitizes the Effects of Gemcitabine in Pancreatic Adenocarcinoma (2009) (279)
Comprehensive toxicity and immunogenicity studies reveal minimal effects in mice following sustained dosing of extracellular vesicles derived from HEK293T cells (2017) (269)
MicroRNAs and cancer: Profile, profile, profile (2007) (223)
The Neuronal MicroRNA miR-326 Acts in a Feedback Loop with Notch and Has Therapeutic Potential against Brain Tumors (2009) (223)
miR-221 silencing blocks hepatocellular carcinoma and promotes survival. (2011) (207)
miR-132 and miR-212 are increased in pancreatic cancer and target the retinoblastoma tumor suppressor. (2011) (173)
microRNA Replacement Therapy for Cancer (2011) (171)
Epigenetic modification of CCAAT/enhancer binding protein alpha expression in acute myeloid leukemia. (2008) (163)
The Human Angiotensin II Type 1 Receptor +1166 A/C Polymorphism Attenuates MicroRNA-155 Binding* (2007) (160)
Human chromosome 21-derived miRNAs are overexpressed in down syndrome brains and hearts. (2008) (156)
miR-199a-3p targets CD44 and reduces proliferation of CD44 positive hepatocellular carcinoma cell lines. (2010) (144)
The human angiotensin II type 1 receptor +1166 A/C polymorphism attenuates microRNA-155 binding. (2013) (140)
MicroRNA-155 regulates human angiotensin II type 1 receptor expression in fibroblasts. (2006) (139)
A methodology for the combined in situ analyses of the precursor and mature forms of microRNAs and correlation with their putative targets (2009) (126)
MiRNA199a-3p suppresses tumor growth, migration, invasion and angiogenesis in hepatocellular carcinoma by targeting VEGFA, VEGFR1, VEGFR2, HGF and MMP2 (2017) (120)
The Extracellular RNA Communication Consortium: Establishing Foundational Knowledge and Technologies for Extracellular RNA Research (2019) (120)
Regulation of microRNA processing in development, differentiation and cancer (2008) (119)
The role of microRNAs in human liver cancers. (2011) (117)
Integrating the MicroRNome into the study of lung disease. (2009) (101)
Tumor Suppressive Function of mir-205 in Breast Cancer Is Linked to HMGB3 Regulation (2013) (99)
Expression of prostate specific membrane antigen and three alternatively spliced variants of PSMA in prostate cancer patients (2003) (94)
Increased expression of microRNA‐155 in Epstein‐Barr virus transformed lymphoblastoid cell lines (2006) (94)
HINCUTs in cancer: hypoxia-induced noncoding ultraconserved transcripts (2013) (93)
Pharmacodynamics of mitomycin C in cultured human bladder tumors. (1991) (88)
Achieving the Promise of Therapeutic Extracellular Vesicles: The Devil is in Details of Therapeutic Loading (2017) (83)
Computational analysis of biological functions and pathways collectively targeted by co-expressed microRNAs in cancer (2007) (80)
Effect of 1-methyl-4-phenyl-1,2,3,6 tetrahydropyridine (MPTP) on monoamine neurotransmitters in mouse brain & heart. (1984) (76)
High-throughput real-time PCR. (2008) (75)
Dietary apigenin reduces LPS-induced expression of miR-155 restoring immune balance during inflammation. (2015) (72)
Strong Inverse Correlation Between MicroRNA-125b and Human Papillomavirus DNA in Productive Infection (2010) (66)
Low active loading of cargo into engineered extracellular vesicles results in inefficient miRNA mimic delivery (2017) (59)
MicroRNAs Are Mediators of Androgen Action in Prostate and Muscle (2010) (56)
In situ detection of mature microRNAs by labeled extension on ultramer templates. (2009) (50)
Benign Metastasizing Leiomyoma of the Lung: Clinicopathologic, Immunohistochemical, and Micro-RNA Analyses (2008) (48)
miR-221 regulates CD44 in hepatocellular carcinoma through the PI3K-AKT-mTOR pathway. (2017) (47)
A Differential MicroRNA Profile Distinguishes Cholangiocarcinoma from Pancreatic Adenocarcinoma (2011) (45)
Globally increased ultraconserved noncoding RNA expression in pancreatic adenocarcinoma (2016) (38)
Concomitant dysregulation of microRNAs miR-151-3p and miR-126 correlates with improved survival in resected cholangiocarcinoma. (2013) (37)
Effect of 5-fluoro- and 5-bromouracil substitution on the translation of human thymidylate synthase mRNA. (1995) (37)
Effects of local structural transformation of lipid-like compounds on delivery of messenger RNA (2016) (35)
Comparison of RNA assay methods used to normalize cDNA for quantitative real-time PCR. (2006) (35)
Characterization of nitric oxide production following isolation of rat hepatocytes. (2000) (34)
Restoration of wild-type p53 activity in p53-null HL-60 cells confers multidrug sensitivity. (1998) (33)
miR-31: a master regulator of metastasis? (2010) (32)
Exosomal miRNA Cargo as Mediator of Immune Escape Mechanisms in Neuroblastoma. (2019) (28)
miR-216 and miR-217 expression is reduced in transgenic mouse models of pancreatic adenocarcinoma, knockout of miR-216/miR-217 host gene is embryonic lethal (2017) (28)
MicroRNAs Targeting Caspase-3 and -7 in PANC-1 Cells (2018) (28)
CD44 positive and sorafenib insensitive hepatocellular carcinomas respond to the ATP-competitive mTOR inhibitor INK128 (2018) (25)
RNA isolation from mouse pancreas: a ribonuclease-rich tissue. (2014) (25)
Cultured human bladder tumors for pharmacodynamic studies. (1991) (23)
Correlation of human bladder tumor histoculture proliferation and sensitivity to mitomycin C with tumor pathobiology. (1994) (23)
Inhibition of pre-mRNA splicing by cisplatin and platinum analogs. (2003) (23)
Pancreatic Cancer Related Health Disparities: A Commentary (2018) (22)
Expression pattern of mouse homolog of prostate‐specific membrane antigen (FOLH1) in the transgenic adenocarcinoma of the mouse prostate model (2003) (21)
Anti-invasion and anti-migration effects of miR-199a-3p in hepatocellular carcinoma are due in part to targeting CD151. (2016) (21)
The pancreatic tumor microenvironment drives changes in miRNA expression that promote cytokine production and inhibit migration by the tumor associated stroma (2016) (20)
Human Colon Mucosal Biofilms and Murine Host Communicate via Altered mRNA and microRNA Expression during Cancer (2020) (20)
Dynamin 2 Regulates Riboflavin Endocytosis in Human Placental Trophoblasts (2007) (19)
MicroRNA-155 Regulates Human Angiotensin II Type 1 Receptor Expression in Fibroblasts* (2006) (18)
Quantitative gene expression by real-time PCR: a complete protocol (2007) (18)
Different pH Dependency of Mitomycin C Activity in Monolayer and Three-Dimensional Cultures (1996) (18)
Apoptosis induced by novel aldehyde calpain inhibitors in human tumor cell lines. (2006) (17)
Glutathione-dependent regulation of nitric oxide production in isolated rat hepatocyte suspensions. (2000) (15)
Expression Profiling Identifies the Noncoding Processed Transcript of HNRNPU with Proliferative Properties in Pancreatic Ductal Adenocarcinoma (2017) (15)
Role of non-coding RNAs in tumor progression and metastasis in pancreatic cancer (2021) (15)
In vitro immunotoxicity assessment of culture-derived extracellular vesicles in human monocytes (2016) (13)
Studies on the Antileishmanial Mechanism of Action of the Arylimidamide DB766: Azole Interactions and Role of CYP5122A1 (2014) (12)
Loss of RE-1 silencing transcription factor accelerates exocrine damage from pancreatic injury (2020) (11)
Correction: Detection of microRNA Expression in Human Peripheral Blood Microvesicles (2010) (10)
Enrichment of the erythrocyte miR-451a in brain extracellular vesicles following impairment of the blood-brain barrier (2021) (10)
Quantitative Real-Time RT-PCR (2006) (10)
Part B--microRNAs: microRNA methods. (2008) (9)
Knockout of Acinar Enriched microRNAs in Mice Promote Duct Formation But Not Pancreatic Cancer (2019) (9)
Alterations in mouse spinal cord and sciatic nerve microRNAs after the chronic constriction injury (CCI) model of neuropathic pain (2020) (6)
Retraction notice to "Human chromosome 21-derived miRNAs are over-expressed in down syndrome brains and hearts" [Biochem. Biophys. Res. Commun. 370 (2008) 473-477]. (2013) (4)
Method for improved integrity of RNA isolated from Matrigel cultures (2020) (4)
Effects of 5-fluorouracil, leucovorin, and glucarate in rat colon-tumor explants (2004) (3)
Expression in Acute Myeloid Leukemia α Epigenetic Modification of CCAAT / Enhancer Binding Protein (2008) (2)
High-Throughput Profiling of Mature MicroRNA by Real-Time PCR (2011) (2)
Diverse gene expression pattern during 5-fluorouridine-induced apoptosis. (2005) (2)
Microbiomarkers with big impact in CLL. (2013) (2)
Dual Epigenetic Control of CCAAT/Enhancer Binding Protein α (C/EBPα) Expression in Acute Myeloid Leukemia. (2007) (1)
Abstract 4322: Exosomal delivery of stroma-derived miR-145 inhibits pancreatic cancer cell proliferation (2017) (1)
Abstract 1183: miR-199a-3p targets CD44 and reduces proliferation of CD44 positive hepatocellular carcinoma cell lines (2011) (1)
In Situ Detection of MicroRNAs in Paraffin-Embedded, Formalin-Fixed Tissues: Different Methodologies and Co-localization with Possible Targets (2011) (1)
Abstract 4187: Regulation of NRSF/REST by miR-217; Implications during pancreatic acinar ductal trans-differentiation. (2013) (1)
MicroRNAs in Cell Death and Cancer (2013) (1)
Abstract 4204: miR-205 functions as a tumor suppressor in breast cancer by targeting HMGB3. (2013) (1)
Enhancing African American Participation in Biospecimens: A Case in Point for Pancreatic Cancer. (2020) (1)
Association of MicroRNAExpression in Hepatocellular Carcinomas with Hepatitis Infection , Cirrhosis , and Patient Survival (2008) (1)
Abstract 2068: Engineering of hairpin loop enhances the loading of endogenously expressed pre-miRNA into extracellular vesicles (2016) (1)
Pharmacological inhibition and reversal of pancreatic acinar ductal metaplasia (2022) (1)
Abstract 780: Transcriptional profile of human pancreatic acinar ductal metaplasia (2022) (1)
Abstract 1179: Global increase in ultraconserved non-coding RNA expression in pancreatic adenocarcinoma (2011) (0)
Hsa-miR-199a-3p by Targeting VEGFA, VEGFR1, VEGFR2, HGF and MMP2 Impedes Inter Crosstalks Between Malignant Hepatocyte and Tumor Microenvironment that Drives in Hepatocellular Carcinoma (2015) (0)
Abstract 141: CD44 positive and sorafenib resistant hepatocellular carcinomas respond to the ATP-competitive mTOR inhibitor INK128 (2017) (0)
Correction for Pandharkar et al., “Studies on the Antileishmanial Mechanism of Action of the Arylimidamide DB766: Azole Interactions and Role of CYP5122A1” (2017) (0)
Method for Isolating Extracellular Vesicles from Human Neural Stem Cells Expanded Under Neurosphere Culture. (2022) (0)
Abstract D112: Development of an organoid assay for studying racial disparity in pancreatic acinar ductal metaplasia (2020) (0)
Expression of miR-205 and HMGB3 are altered in 5-Aza and TSA treated cells. (2013) (0)
Achieving the Promise of Therapeutic Extracellular Vesicles: The Devil is in Details of Therapeutic Loading (2017) (0)
Abstract PO-160: Association between variants in acinar-to-ductal metaplasia genes and pancreatic cancer incidence in racially diverse populations (2020) (0)
Abstract PO-092: Development of an organoid assay for studying racial disparity in pancreatic acinar ductal metaplasia (2020) (0)
Non‐coding RNAs as Markers of Neuropathic Pain (2019) (0)
Abstract 5222: Repression of neuronal genes protects the pancreas from certain injuries and aberrant plasticity (2019) (0)
Cirrhosis-related microRNA expression profile in hepatocellular carcinoma and benign liver tissues (2005) (0)
Abstract C048: Computational pathway analysis of differentially expressed miRNAs in Black compared with White laryngeal squamous cell carcinoma (2023) (0)
Knockdown of HMGB3 reduces the proliferation and in vitro invasion of breast cancer cells. (2013) (0)
Abstract PR003: Race plays a role on the rate of transdifferentiation in human pancreatic acinar ductal metaplasia and its' drug response (2022) (0)
Abstract 3956: Differential miR-141 expression in primary cultured human breast cancer epithelium (PCHBCEs) and normal adjacent part epithelium (PCHBNEs) correlates with tumor suppressor protein tyrosine phosphataseγ (PTPγ) (2011) (0)
miR-205 is down-regulated in breast cancer. (2013) (0)
Pharmacological inhibition and reversal of pancreatic acinar ductal metaplasia (2022) (0)
Procedes de quantification de precurseurs de micro-arn (2006) (0)
Abstract 2106: Regulation of Rb1 and caspase 3/7 by miR-17-5p, miR-132/-212, and miR-337-3p: Oncogenic role of miRNAs in pancreatic cancer (2010) (0)
Abstract 5821: Enhanced tumorigenesis in a novel miR-216a knockout/KPC mouse model of pancreatic cancer (2022) (0)
Novel clone selection technique reveals heterogeneity among HEK293T cells engineered to produce therapeutic extracellular vesicles (2017) (0)
Simultaneous Detection of Primary, Precursor and Mature MicroRNAs by qPCR (2010) (0)
DDRE-14. HEMP DERIVED EXTRACELLULAR VESICLES (EVS): A POTENTIAL ANTI-GLIOMA THERAPY (2020) (0)
Transcribed ultraconserved regions are aberrantly expressed and can be modulated by interleukin 6 in cholangiocarcinoma (2013) (0)
Abstract 3583: Differential expression of noncoding RNAs in black compared with white laryngeal cancers (2019) (0)
Abstract 5777: Race as a predictive confounder in the rate of transdifferentiation and drug response in human pancreatic acinar ductal metaplasia (2023) (0)
Loss of RE-1 silencing transcription factor accelerates exocrine damage from pancreatic injury (2020) (0)
Abstract 1374: MicroRNA-155 Regulates Human Angiotensin II Type 1 Receptor Expression in Human Vascular Smooth Muscle Cells (2006) (0)
HMGB3 is a target of miR-205 in breast cancer. (2013) (0)
Pathology, genetic alterations, and targets of differentially expressed microRNAs in pancreatic cancer (2014) (0)
Animal Symposia A-2 Isolation and Growth of Embryonic and Induced Pluripotent Stem Cells (0)
miR-216 and miR-217 expression is reduced in transgenic mouse models of pancreatic adenocarcinoma, knockout of miR-216/miR-217 host gene is embryonic lethal (2016) (0)
Abstract 4711: Silencing of miR-221 with anti-microRNA oligonucleotides is an effective therapeutic for hepatocellular carcinoma (2011) (0)
Acinar cell enriched-microRNA-802 connects the dots between Kras signaling, acinar ductal metaplasia and pancreatic cancer. (2021) (0)
Animal Symposia (2014) (0)
Disclosing quantitative RT‐PCR raw data during manuscript submission: a call for action (2023) (0)
Pharmacodynamics of antiproliferative agents in patient and rodent tumor explants (1992) (0)

This paper list is powered by the following services:

What Schools Are Affiliated With Thomas D. Schmittgen?

Thomas D. Schmittgen is affiliated with the following schools:

Ohio State University
University of Florida
University of California, San Francisco