Thomas Gridley
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Thomas Gridleybiology Degrees
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Cell Biology
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Genetics
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Molecular Biology
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Biology
Thomas Gridley's Degrees
- Masters Molecular Biology Stanford University
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(Suggest an Edit or Addition)Thomas Gridley's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation (1995) (1861)
- Notch signaling is essential for vascular morphogenesis in mice. (2000) (1068)
- Embryonic lethality and vascular defects in mice lacking the Notch ligand Jagged1. (1999) (798)
- Notch1 is essential for postimplantation development in mice. (1994) (761)
- The Mouse Snail Gene Encodes a Key Regulator of the Epithelial-Mesenchymal Transition (2001) (621)
- Hoxa-2 mutant mice exhibit homeotic transformation of skeletal elements derived from cranial neural crest (1993) (562)
- Properties and applications of monoclonal antibodies directed against determinants of the Thy-1 locus. (1979) (544)
- Haploinsufficient lethality and formation of arteriovenous malformations in Notch pathway mutants. (2004) (533)
- Roles for Nkx3.1 in prostate development and cancer. (1999) (496)
- Perinatal lethality and defects in hindbrain development in mice homozygous for a targeted mutation of the zinc finger gene Krox20. (1993) (487)
- Notch3 is required for arterial identity and maturation of vascular smooth muscle cells. (2004) (487)
- Notch signalling pathway mediates hair cell development in mammalian cochlea (1999) (472)
- A mouse model of Alagille syndrome: Notch2 as a genetic modifier of Jag1 haploinsufficiency. (2002) (462)
- Defects in limb, craniofacial, and thymic development in Jagged2 mutant mice. (1998) (432)
- Direct regulation of Gata3 expression determines the T helper differentiation potential of Notch. (2007) (432)
- Defects in somite formation in lunatic fringe-deficient mice (1998) (414)
- Notch signaling in vascular development and physiology (2007) (413)
- Notch Activity Influences the αβ versus γδ T Cell Lineage Decision (1997) (403)
- Jagged1 is the pathological link between Wnt and Notch pathways in colorectal cancer (2009) (373)
- Defects in development of the kidney, heart and eye vasculature in mice homozygous for a hypomorphic Notch2 mutation. (2001) (369)
- gamma-secretase functions through Notch signaling to maintain skin appendages but is not required for their patterning or initial morphogenesis. (2004) (304)
- Notch signaling and inherited disease syndromes. (2003) (297)
- The Notch Ligand JAG1 Is Required for Sensory Progenitor Development in the Mammalian Inner Ear (2006) (284)
- Goosecoid is not an essential component of the mouse gastrula organizer but is required for craniofacial and rib development. (1995) (264)
- The Notch ligands DLL1 and JAG2 act synergistically to regulate hair cell development in the mammalian inner ear (2005) (261)
- The Slug gene is not essential for mesoderm or neural crest development in mice. (1998) (260)
- Characterization of Notch3‐deficient mice: Normal embryonic development and absence of genetic interactions with a Notch1 mutation (2003) (259)
- Developmental transcription factor slug is required for effective re‐epithelialization by adult keratinocytes (2005) (251)
- Expression pattern of Motch, a mouse homolog of Drosophila Notch, suggests an important role in early postimplantation mouse development. (1992) (247)
- Notch signaling in the vasculature. (2010) (240)
- A requirement for Notch1 distinguishes 2 phases of definitive hematopoiesis during development. (2004) (238)
- Notch signaling regulates left-right asymmetry determination by inducing Nodal expression. (2003) (236)
- Brain lipid-binding protein is a direct target of Notch signaling in radial glial cells. (2005) (229)
- Critical Role of Endothelial Notch1 Signaling in Postnatal Angiogenesis (2007) (207)
- The type II activin receptors are essential for egg cylinder growth, gastrulation, and rostral head development in mice. (1999) (203)
- Interaction between Reelin and Notch Signaling Regulates Neuronal Migration in the Cerebral Cortex (2008) (202)
- Impaired embryonic haematopoiesis yet normal arterial development in the absence of the Notch ligand Jagged1 (2008) (198)
- Notch activity influences the alphabeta versus gammadelta T cell lineage decision. (1997) (180)
- Repression of PTEN Phosphatase by Snail1 Transcriptional Factor during Gamma Radiation-Induced Apoptosis (2008) (180)
- Notch Signaling in Vertebrate Development and Disease (1997) (178)
- Ectopic Hoxa-1 induces rhombomere transformation in mouse hindbrain. (1994) (178)
- Isolation of Sna, a mouse gene homologous to the Drosophila genes snail and escargot: its expression pattern suggests multiple roles during postimplantation development. (1992) (151)
- The Nrarp gene encodes an ankyrin-repeat protein that is transcriptionally regulated by the notch signaling pathway. (2001) (145)
- Blockade of individual Notch ligands and receptors controls graft-versus-host disease. (2013) (143)
- Parent stem cells can serve as niches for their own daughter cells (2015) (143)
- Krox-20 controls SCIP expression, cell cycle exit and susceptibility to apoptosis in developing myelinating Schwann cells. (1999) (138)
- Notch2 governs the rate of generation of mouse long- and short-term repopulating stem cells. (2011) (138)
- Notch Signaling Regulates Bile Duct Morphogenesis in Mice (2008) (136)
- A mutation in the Lunatic fringe gene suppresses the effects of a Jagged2 mutation on inner hair cell development in the cochlea (2000) (129)
- Retroviruses and insertional mutagenesis in mice: proviral integration at the Mov 34 locus leads to early embryonic death. (1987) (124)
- Cloning, analysis, and chromosomal localization of Notch-1, a mouse homolog of Drosophila Notch. (1993) (113)
- Multiple functions of Snail family genes during palate development in mice (2007) (113)
- Lunatic fringe deficiency cooperates with the Met/Caveolin gene amplicon to induce basal-like breast cancer. (2012) (109)
- Snail family genes are required for left–right asymmetry determination, but not neural crest formation, in mice (2006) (108)
- Smooth Muscle Notch1 Mediates Neointimal Formation After Vascular Injury (2009) (106)
- Slug Is a Novel Downstream Target of MyoD (2002) (105)
- Generation of new Notch2 mutant alleles (2006) (103)
- Notch2 is required in somatic cells for breakdown of ovarian germ-cell nests and formation of primordial follicles (2013) (103)
- TCF and Groucho-related genes influence pituitary growth and development. (2003) (100)
- The archetypal R90C CADASIL-NOTCH3 mutation retains NOTCH3 function in vivo. (2007) (99)
- Insertional mutagenesis in mice (1987) (96)
- Jag2‐Notch1 signaling regulates oral epithelial differentiation and palate development (2006) (96)
- The molecular evolution of the immune response. (1985) (96)
- Bile duct proliferation in liver‐specific Jag1 conditional knockout mice: Effects of gene dosage (2007) (95)
- Notch1 activation in mice causes arteriovenous malformations phenocopied by ephrinB2 and EphB4 mutants (2010) (93)
- Notch signaling coordinates the patterning of striatal compartments (2005) (92)
- Craniosynostosis in Twist heterozygous mice: A model for Saethre‐Chotzen syndrome (2002) (89)
- Segmentation defects of Notch pathway mutants and absence of a synergistic phenotype in lunatic fringe/radical fringe double mutant mice (2002) (88)
- Molecular Pathways of Notch Signaling in Vascular Smooth Muscle Cells (2012) (87)
- Notch signaling during vascular development (2001) (85)
- Specific Notch receptor–ligand interactions control human TCR-αβ/γδ development by inducing differential Notch signal strength (2013) (85)
- Oncogenic activation of the Notch1 gene by deletion of its promoter in Ikaros-deficient T-ALL. (2010) (81)
- Lunatic fringe, FGF, and BMP regulate the Notch pathway during epithelial morphogenesis of teeth. (2002) (80)
- Lunatic Fringe-mediated Notch signaling is required for lung alveogenesis. (2010) (80)
- BMPs and FGFs target Notch signalling via jagged 2 to regulate tooth morphogenesis and cytodifferentiation (2010) (76)
- Notch 3 is required for arterial identity and maturation of vascular smooth muscle cells (2004) (76)
- Neural tube defects and neuroepithelial cell death in Tulp3 knockout mice. (2001) (75)
- Mice homozygous for a null mutation of activin β B are viable and fertile (1994) (74)
- Development of the mammalian ear: coordinate regulation of formation of the tympanic ring and the external acoustic meatus. (1996) (73)
- Single germline VH and V kappa genes encode predominating antibody variable regions elicited in strain A mice by immunization with p- azophenylarsonate (1987) (72)
- Mice mutant for Ppap2c, a homolog of the germ cell migration regulator wunen, are viable and fertile (2000) (71)
- Expression of proneural and neurogenic genes in the embryonic mammalian vestibular system (1999) (70)
- Cloning and developmental expression of Grg, a mouse gene related to the groucho transcript of the Drosophila Enhancer of split complex (1993) (69)
- Patent ductus arteriosus in mice with smooth muscle-specific Jag1 deletion (2010) (67)
- Role of the Notch signalling pathway in tooth morphogenesis. (2005) (66)
- Cell movements during gastrulation: snail dependent and independent pathways. (2002) (66)
- Loss of Notch Activity in the Developing Central Nervous System Leads to Increased Cell Death (2006) (63)
- Notch controls the magnitude of T helper cell responses by promoting cellular longevity (2012) (63)
- Snail1 controls TGF-β responsiveness and differentiation of Mesenchymal Stem Cells (2012) (62)
- The long and short of it: Somite formation in mice (2006) (55)
- Differential screening of a PCR-generated mouse embryo cDNA library: glucose transporters are differentially expressed in early postimplantation mouse embryos. (1992) (53)
- Mmp15 is a direct target of Snai1 during endothelial to mesenchymal transformation and endocardial cushion development. (2011) (52)
- Notch Activity Influences the a versus ?d T Cell Lineage Decision (1997) (51)
- Fine-tuning of Notch signaling sets the boundary of the organ of Corti and establishes sensory cell fates (2016) (49)
- Snai1 regulates cell lineage allocation and stem cell maintenance in the mouse intestinal epithelium (2015) (47)
- Notch2 is required for maintaining sustentacular cell function in the adult mouse main olfactory epithelium. (2008) (45)
- DLL4/Notch1 and BMP9 Interdependent Signaling Induces Human Endothelial Cell Quiescence via P27KIP1 and Thrombospondin-1 (2015) (44)
- The association of various D elements with a single-immunoglobulin VH gene segment: influence on the expression of a major cross-reactive idiotype. (1985) (42)
- Molecular analysis of the Mov 34 mutation: transcript disrupted by proviral integration in mice is conserved in Drosophila. (1990) (41)
- Compensatory regulation of the Snai1 and Snai2 genes during chondrogenesis (2013) (41)
- Generation of a Snail1 (Snai1) conditional null allele (2006) (40)
- Snail regulates p21(WAF/CIP1) expression in cooperation with E2A and Twist. (2004) (38)
- The Developmental Transcription Factor Slug Is Widely Expressed in Tissues of Adult Mice (2004) (37)
- Roles for Nkx 3 . 1 in prostate development and cancer (2009) (36)
- Epiblast-specific Snai1 deletion results in embryonic lethality due to multiple vascular defects (2009) (35)
- Slug expression during organogenesis in mice. (2003) (34)
- Notch1 expression and ligand interactions in progenitor cells of the mouse olfactory epithelium (2007) (34)
- Mutation of a Ubiquitously Expressed Mouse Transmembrane Protein (Tapt1) Causes Specific Skeletal Homeotic Transformations (2007) (33)
- Growth defect in Grg5 null mice is associated with reduced Ihh signaling in growth plates (2002) (33)
- Protein characterization and targeted disruption of Grg, a mouse gene related to the groucho transcript of the Drosophila enhancer of split complex (1995) (33)
- Mesenchymal cell remodeling during mouse secondary palate reorientation (2010) (33)
- Conditional Deletion of Notch1 and Notch2 Genes in Excitatory Neurons of Postnatal Forebrain Does Not Cause Neurodegeneration or Reduction of Notch mRNAs and Proteins* (2012) (31)
- Generation of mice with a conditional null allele of the Jagged2 gene (2010) (31)
- Vascular Biology: Vessel guidance (2007) (31)
- Insertional versus targeted mutagenesis in mice. (1991) (29)
- Notch Signaling during Oogenesis in Drosophila melanogaster (2012) (29)
- Mice homozygous for a null mutation of activin beta B are viable and fertile. (1994) (28)
- Genetic Background Modifies Inner Ear and Eye Phenotypes of Jag1 Heterozygous Mice (2007) (26)
- Snail1 Gene Function During Early Embryo Patterning in Mice (2006) (25)
- Gene targeting: Things go better with Cre (1997) (23)
- Mutations in Snail Family Genes Enhance Craniosynostosis of Twist1 Haplo-insufficient Mice (2005) (23)
- The murine Mov-34 gene: full-length cDNA and genomic organization. (1991) (21)
- Snail family genes are required for left–right asymmetry determination but not neural crest formation in mice (2006) (19)
- Smooth Muscle Notch 1 Mediates Neointimal Formation After Vascular Injury (2009) (19)
- Cloning, sequencing and expression of the mouse mammalian achaete-scute homolog 1 (MASH1). (1993) (19)
- The SNAI1 and SNAI2 proteins occupy their own and each other's promoter during chondrogenesis. (2013) (17)
- Mouse TCOF1 is expressed widely, has motifs conserved in nucleolar phosphoproteins, and maps to chromosome 18. (1997) (17)
- The Snail Family Gene Snai3 Is Not Essential for Embryogenesis in Mice (2013) (17)
- Identification of transgenic mice. (1993) (16)
- Molecular limitations on variable-gene junctional diversity. (1986) (15)
- Stromal SNAI2 Is Required for ERBB2 Breast Cancer Progression (2020) (15)
- Genomic organization, expression and chromosomal localization of the mouse Slug (Slugh) gene. (1998) (15)
- Lightening up a notch: Notch regulation of energy metabolism (2014) (15)
- Kick it up a Notch: NOTCH1 activation in T-ALL. (2004) (14)
- Notch4 is required for tumor onset and perfusion (2013) (14)
- Notch signal reception is required in vascular smooth muscle cells for ductus arteriosus closure (2016) (13)
- Genomic organization, alternative polyadenylation, and chromosomal localization of Grg, a mouse gene related to the groucho transcript of the Drosophila Enhancer of split complex. (1994) (13)
- Notch, stroke and dementia (1996) (12)
- Jagged1-mediated Notch signaling regulates mammalian inner ear development independent of lateral inhibition (2012) (11)
- Notch2 and Proteomic Signatures in Mouse Neointimal Lesion Formation (2018) (11)
- Laser surgery for mouse geneticists (2007) (10)
- Specific Notch receptor–ligand interactions control human TCR-ab/gd development by inducing differential Notch signal strength (2013) (9)
- A new role of SNAI2 in post-lactational involution of the mammary gland links it to luminal breast cancer development (2015) (9)
- Loss of Snail2 favors skin tumor progression by promoting the recruitment of myeloid progenitors. (2015) (9)
- Not all lunatic fringe null female mice are infertile (2006) (8)
- Endoglin is required in Pax3-derived cells for embryonic blood vessel formation. (2016) (7)
- Notch1 and Notch2 collaboratively maintain radial glial cells in mouse neurogenesis (2020) (7)
- Notch Dosage: Jagged1 Haploinsufficiency Is Associated With Reduced Neuronal Division and Disruption of Periglomerular Interneurons in Mice (2020) (6)
- Overview of genetic tools and techniques to study Notch signaling in mice. (2014) (6)
- A new role of SNAI2 in postlactational involution of the mammary gland links it to luminal breast cancer development (2015) (6)
- function in vivo (2007) (6)
- Possible involvement of the mouse Grg protein in transcription. (1995) (5)
- reply: Limbs move beyond the Radical fringe (1999) (5)
- The Notch-Regulated Ankyrin Repeat Protein Is Required for Proper Anterior–Posterior Somite Patterning in Mice (2011) (5)
- Cloning, expression, and chromosomal localization of a mouse gene homologous to the germ cell migration regulator wunen and to type 2 phosphatidic acid phosphatases. (2000) (4)
- Human Genetics. Notch, stroke and dementia. (1996) (4)
- The Snail Transcription Factor Regulates the Numbers of Neural Precursor Cells and Newborn Neurons throughout Mammalian Life (2014) (4)
- Absence of a Major Role for the Snai1 and Snai3 Genes in Regulating Skeletal Muscle Regeneration in Mice (2013) (4)
- Assignment of the murine Notch2 and Notch3 genes to chromosomes 3 and 17. (1998) (3)
- Vertebrate Homologs of the Neurogenic Genes of Drosophila (1996) (3)
- Mouse mutagenesis and phenotyping to generate models of development and disease. (2022) (3)
- The role of antigen-driven selection in the expression and control of idiotypes. (1984) (2)
- Developmental Mutations Generated by Retroviral Insertional Mutagenesis (1992) (2)
- Arteriovenous Patterning in the Vascular System (2010) (1)
- 99 PROGENITOR CELL ACTIVATION AND LIVER REPAIR IS ALTERED IN NOTCH2- AND RBP-Jκ-DEFECTIVE MICE EXPOSED TO CHOLESTATIC INJURIES (2010) (1)
- Notch2 is required in somatic cells for breakdown of ovarian germ-cell nests and formation of primordial follicles (2013) (1)
- DIO3 protects against thyrotoxicosis-derived cranio-encephalic and cardiac congenital abnormalities (2022) (1)
- The Jagged2 gene maps to Chromosome 12 and is a candidate for the lgl and sm mutations (2009) (1)
- OC8 Defective progenitor cells activation and biliary tubule formation in liver conditional RBP-Jk-knock out mice exposed to cholestatic injuries reveals a key role for Notch signaling in liver repair (2010) (1)
- Exclusion of Jagged2 as a candidate for the legless gene (1998) (1)
- Genomic organization and chromosomal localization of the mouse snail (Sna) gene (1997) (1)
- Human Genetics. Notch, stroke and dementia [news; comment] (1996) (0)
- Reply to Gaiano et al.: Expression of Notch Proteins in Pyramidal Neurons in Vivo (2012) (0)
- Notch2 Regulates Early Folliculogenesis in Mice. (2009) (0)
- F.N.3 PROGENITOR CELL ACTIVATION AND LIVER REPAIR IS ALTERED IN NOTCH2- AND RBP-Jκ-DEFECTIVE MICE EXPOSED TO CHOLESTATIC INJURIES (2010) (0)
- Muscle Regeneration JBC Word2000.PDF (2002) (0)
- Mouse models of development and disease: Preface. (2022) (0)
- Decision letter: A Tgfbr1/Snai1-dependent developmental module at the core of vertebrate axial elongation (2020) (0)
- Regulatory interplay between microRNAs and Snail family proteins in cancer (2014) (0)
- Twenty Years in Maine: Integrating Insights from Developmental Biology into Translational Medicine in a Small State. (2016) (0)
- Multiple functions of Snail family members in palate development and craniofacial morphogenesis (2007) (0)
- Epithelial-mesenchymal transitions and cancer (2002) (0)
- Author response: Fine-tuning of Notch signaling sets the boundary of the organ of Corti and establishes sensory cell fates (2016) (0)
- Conditional Deletion of Notch2 in Lens (2010) (0)
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