Thomas J. Dougherty

Thomas J. Dougherty's AcademicInfluence.com Rankings

Thomas J. Dougherty

Chemistry

#971

World Rank

#1570

Historical Rank

Chemical Engineering

#46

World Rank

#55

Historical Rank

chemistry Degrees

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Chemistry

Thomas J. Dougherty's Degrees

PhD Chemical Engineering Stanford University
Masters Chemical Engineering Stanford University

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Thomas J. Dougherty's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

A Mechanism for Non‐Newtonian Flow in Suspensions of Rigid Spheres (1959) (2681)
Photodynamic therapy. (1993) (2668)
HOW DOES PHOTODYNAMIC THERAPY WORK? (1992) (2296)
Identification of singlet oxygen as the cytotoxic agent in photoinactivation of a murine tumor. (1976) (1544)
Photoradiation therapy for the treatment of malignant tumors. (1978) (1534)
Basic principles of photodynamic therapy (2001) (1254)
Ceramic-based nanoparticles entrapping water-insoluble photosensitizing anticancer drugs: a novel drug-carrier system for photodynamic therapy. (2003) (849)
Photodynamic therapy. (1992) (847)
PHOTOSENSITIZERS: THERAPY AND DETECTION OF MALIGNANT TUMORS (1987) (808)
Photoradiation therapy. II. Cure of animal tumors with hematoporphyrin and light. (1975) (653)
Photodynamic Therapy (1988) (635)
An update on photodynamic therapy applications. (2002) (548)
Determination of [3H]- and [14C]hematoporphyrin derivative distribution in malignant and normal tissue. (1979) (514)
Tumor destruction and kinetics of tumor cell death in two experimental mouse tumors following photodynamic therapy. (1985) (478)
Photoradiation in the treatment of recurrent breast carcinoma. (1979) (425)
Autoradiographic distribution of hematoporphyrin derivative in normal and tumor tissue of the mouse. (1981) (349)
Cutaneous phototoxic occurrences in patients receiving Photofrin® (1990) (294)
Photodynamic therapy (PDT) of malignant tumors. (1984) (273)
PHOTOBLEACHING OF PORPHYRINS USED IN PHOTODYNAMIC THERAPY AND IMPLICATIONS FOR THERAPY (1987) (268)
The structure of the active component of hematoporphyrin derivative. (1984) (236)
Identification of 113 conserved essential genes using a high-throughput gene disruption system in Streptococcus pneumoniae. (2002) (224)
An in vivo quantitative structure-activity relationship for a congeneric series of pyropheophorbide derivatives as photosensitizers for photodynamic therapy. (1997) (195)
Photosensitization of malignant tumors. (1986) (188)
DISTRIBUTION AND ELIMINATION OF PHOTOFRIN II IN MICE (1989) (188)
STUDIES ON THE STRUCTURE OF PORPHYRINS CONTAINED IN PHOTOFRIN® II (1987) (170)
Synthesis, photophysical properties, tumor uptake, and preliminary in vivo photosensitizing efficacy of a homologous series of 3-(1'-alkyloxy)ethyl-3-devinylpurpurin-18-N-alkylimides with variable lipophilicity. (2001) (168)
CHLORIN AND PORPHYRIN DERIVATIVES AS POTENTIAL PHOTOSENSITIZERS IN PHOTODYNAMIC THERAPY (1991) (158)
Photoradiation therapy--clinical and drug advances. (1983) (153)
THE THEORY OF PHOTODYNAMIC THERAPY DOSIMETRY: CONSEQUENCES OF PHOTO‐DESTRUCTION OF SENSITIZER (1987) (151)
Photoradiation therapy for cutaneous and subcutaneous malignancies. (1981) (150)
Nature: A rich source for developing multifunctional agents. tumor‐imaging and photodynamic therapy (2006) (146)
Penicillin-binding proteins of penicillin-susceptible and intrinsically resistant Neisseria gonorrhoeae (1980) (144)
Photodynamic therapy (PDT) in the treatment of patients with resistant superficial bladder cancer: a long-term experience. (1998) (144)
Photodynamic therapy for the treatment of basal cell carcinoma. (1992) (142)
Energetics and efficiency of photoinactivation of murine tumor cells containing hematoporphyrin. (1976) (138)
Activated dyes as antitumor agents. (1974) (136)
Alkyl Ether Analogs of Chlorophyll‐a Derivatives: Part 1. Synthesis, Photophysical Properties and Photodynamic Efficacy (1996) (136)
Interaction of photodynamic therapy and hyperthermia: tumor response and cell survival studies after treatment of mice in vivo. (1985) (122)
Interstitial photoradiation therapy for primary solid tumors in pet cats and dogs. (1981) (122)
Population pharmacokinetics of the photodynamic therapy agent 2-[1-hexyloxyethyl]-2-devinyl pyropheophorbide-a in cancer patients. (2003) (122)
Subcellular Localization Patterns and Their Relationship to Photodynamic Activity of Pyropheophorbide‐a Derivatives (1999) (119)
Operation and photodynamic therapy for pleural mesothelioma: 6-year follow-up. (1998) (119)
Fluorescence bronchoscopy for detection of lung cancer. (1979) (115)
Antibiotic Discovery and Development (2012) (115)
Photodynamic therapy--new approaches. (1989) (113)
HEMATOPORPHYRIN AS A PHOTOSENSITIZER OF TUMORS * (1983) (108)
Substitution of lysine at position 104 or 240 of TEM-1pTZ18R beta-lactamase enhances the effect of serine-164 substitution on hydrolysis or affinity for cephalosporins and the monobactam aztreonam. (1991) (101)
Interaction of hyperthermia and photoradiation therapy. (1984) (100)
Direct quantitation of the number of individual penicillin-binding proteins per cell in Escherichia coli (1996) (100)
Photodynamic therapy for head and neck dysplasia and cancer. (2009) (98)
Murine pharmacokinetics and antitumor efficacy of the photodynamic sensitizer 2-[1-hexyloxyethyl]-2-devinyl pyropheophorbide-a. (1993) (93)
Synthesis of beta-galactose-conjugated chlorins derived by enyne metathesis as galectin-specific photosensitizers for photodynamic therapy. (2001) (92)
A brief history of clinical photodynamic therapy development at Roswell Park Cancer Institute. (1996) (92)
Photodynamic therapy in patients with colorectal cancer (1986) (89)
Mild skin photosensitivity in cancer patients following injection of Photochlor (2-[1-hexyloxyethyl]-2-devinyl pyropheophorbide-a; HPPH) for photodynamic therapy (2005) (87)
Anti-Angiogenic Activity of Selected Receptor Tyrosine Kinase Inhibitors, PD166285 and PD173074: Implications for Combination Treatment with Photodynamic Therapy (2004) (87)
Protoporphyrin IX occurs naturally in colorectal cancers and their metastases. (2001) (85)
Endobronchial photodynamic therapy for lung cancer (2006) (84)
Potentiation of photodynamic therapy by heat: Effect of sequence and time interval between treatments in vivo (1985) (83)
Studies on the mechanism of tumor destruction by photoradiation therapy. (1984) (83)
An evaluation of photodynamic therapy in the management of cutaneous metastases of breast cancer. (1993) (80)
Synthesis, photophysical properties, in vivo photosensitizing efficacy, and human serum albumin binding properties of some novel bacteriochlorins. (1997) (79)
Efflux in bacteria: what do we really know about it? (2001) (78)
Specificity of DNA uptake in genetic transformation of gonococci. (1979) (78)
MEMBRANE LYSIS IN CHINESE HAMSTER OVARY CELLS TREATED WITH HEMATOPORPHYRIN DERIVATIVE PLUS LIGHT (1982) (77)
Activity of cefepime against ceftazidime- and cefotaxime-resistant gram-negative bacteria and its relationship to beta-lactamase levels (1989) (75)
Concordance analysis of microbial genomes. (1998) (74)
Porphyrin dimers as photosensitizers in photodynamic therapy. (1990) (72)
Clinical Pharmacokinetics of the PDT Photosensitizers Porfimer Sodium (Photofrin), 2‐[1‐Hexyloxyethyl]‐2‐Devinyl Pyropheophorbide‐a (Photochlor) and 5‐ALA‐Induced Protoporphyrin IX (2006) (72)
Extensive and Genome-Wide Changes in the Transcription Profile of Staphylococcus aureus Induced by Modulating the Transcription of the Cell Wall Synthesis Gene murF (2006) (72)
Novel Antibacterial Targets and Compounds Revealed by a High-Throughput Cell Wall Reporter Assay (2015) (71)
Comparison of cefepime, cefpirome, and cefaclidine binding affinities for penicillin-binding proteins in Escherichia coli K-12 and Pseudomonas aeruginosa SC8329 (1991) (70)
Photoradiation therapy in advanced carcinoma of the trachea and bronchus. (1984) (69)
Aspects of the cellular uptake and retention of hematoporphyrin derivative and their correlation with the biological response to PRT in vitro. (1983) (67)
2‐[1‐hexyloxyethyl]‐2‐devinyl pyropheophorbide‐a (HPPH) in a nude rat glioma model: Implications for photodynamic therapy (2001) (66)
Bacteriopurpurinimides: highly stable and potent photosensitizers for photodynamic therapy. (2002) (65)
Association between early inhibition of DNA synthesis and the MICs and MBCs of carboxyquinolone antimicrobial agents for wild-type and mutant [gyrA nfxB(ompF) acrA] Escherichia coli K-12 (1988) (65)
Methyl pyropheophorbide-a analogues: potential fluorescent probes for the peripheral-type benzodiazepine receptor. Effect of central metal in photosensitizing efficacy. (2005) (62)
TIME and SEQUENCE DEPENDENT INFLUENCE OF IN VITRO PHOTODYNAMIC THERAPY (PDT) SURVIVAL BY HYPERTHERMIA (1985) (61)
Purpurinimide carbohydrate conjugates: effect of the position of the carbohydrate moiety in photosensitizing efficacy. (2007) (60)
Operation and intracavitary photodynamic therapy for malignant pleural mesothelioma: a phase II study. (1994) (60)
Genetic analysis and penicillin-binding protein alterations in Neisseria gonorrhoeae with chromosomally mediated resistance (1986) (60)
Staphylococcus haemolyticus contains two D-glutamic acid biosynthetic activities, a glutamate racemase and a D-amino acid transaminase (1995) (59)
Photodynamic therapy for palliation of locally recurrent breast carcinoma. (1987) (59)
Photodynamic therapy in the management of resistant lower urinary tract carcinoma (1987) (58)
Intracavitary photodynamic therapy for malignant pleural mesothelioma. (1995) (58)
Differences in the resistant variants of Enterobacter cloacae selected by extended-spectrum cephalosporins (1996) (57)
Hyperthermic potentiation of photodynamic therapy employing photofrin I and II: Comparison of results using three animal tumor models (1987) (57)
REVIEW Photodynamic Therapy (1998) (56)
Synthesis, comparative photosensitizing efficacy, human serum albumin (site II) binding ability, and intracellular localization characteristics of novel benzobacteriochlorins derived from vic-dihydroxybacteriochlorins. (2003) (56)
Photochemistry in the treatment of cancer (1993) (55)
Identification and characterization of cell wall-cell division gene clusters in pathogenic gram-positive cocci (1997) (54)
A preliminary pharmacokinetic study of intravenous Photofrin in patients. (1996) (54)
Membrane permeability changes associated with DNA gyrase inhibitors in Escherichia coli (1985) (54)
Temperature rise during photoradiation therapy of malignant tumors. (1983) (54)
Effect of meso-substituents on the osmium tetraoxide reaction and pinacol-pinacolone rearrangement of the corresponding vic-dihydroxyporphyrins. (2001) (53)
Correlation between Site ll‐Specific Human Serum Albumin (HSA) Binding Affinity and Murine in vivo Photosensitizing Efficacy of Some Photofrin Components (1997) (52)
Whole bladder photodynamic therapy for transitional cell carcinoma of bladder. (1985) (51)
CHARACTERIZATION OF INTRA‐TUMORAL PORPHYRIN FOLLOWING INJECTION OF HEMATOPORPHYRIN DERIVATIVE OR ITS PURIFIED COMPONENT * (1987) (50)
Photodynamic therapy (PDT) using HPPH for the treatment of precancerous lesions associated with barrett's esophagus (2011) (50)
Bacteriochlorophyll-a as photosensitizer for photodynamic treatment of transplantable murine tumors. (1991) (48)
Structure/activity relationships among photosensitizers related to pheophorbides and bacteriopheophorbides (1992) (47)
Discovery of azetidinyl ketolides for the treatment of susceptible and multidrug resistant community-acquired respiratory tract infections. (2009) (46)
Photodynamic therapy for residual neoplasms of the perianal skin (2000) (46)
THE TIME COURSE OF CUTANEOUS PORPHYRIN PHOTOSENSITIZATION IN THE MURINE EAR (1989) (46)
Fluorescence detection of tumors early diagnosis of microscopic lesions in preclinical studies (1993) (46)
Photofrin photodynamic therapy for treatment of AIDS-related cutaneous Kaposi's sarcoma. (1999) (46)
Photodynamic therapy for the treatment of periocular squamous cell carcinoma in horses: a pilot study. (2008) (45)
Cloning and identification of the Escherichia coli murB DNA sequence, which encodes UDP-N-acetylenolpyruvoylglucosamine reductase (1992) (45)
Syntheses of stable bacteriochlorophyll-a derivatives as potential photosensitizers for photodynamic therapy (1996) (44)
A dose ranging study of photodynamic therapy with porfimer sodium (Photofrin®) for treatment of basal cell carcinoma (2006) (43)
Phototherapy of Human Tumors (1977) (42)
Intra-abdominal applications of hematoporphyrin photoradiation therapy. (1983) (42)
Intraoperative photodynamic therapy for retroperitoneal sarcomas (1988) (40)
Efficient synthesis of porphyrin dimers with carbon-carbon linkages (1990) (39)
Analysis of Neisseria gonorrhoeae peptidoglycan by reverse-phase, high-pressure liquid chromatography (1985) (38)
Involvement of a change in penicillin target and peptidoglycan structure in low-level resistance to beta-lactam antibiotics in Neisseria gonorrhoeae (1985) (37)
Direct Quantitation of the Numbers of Individual Penicillin-Binding Proteins per Cell in Staphylococcus aureus (2002) (36)
Syntheses of hematoporphyrin dimers and trimers with ether linkages (1988) (36)
NBTI 5463 Is a Novel Bacterial Type II Topoisomerase Inhibitor with Activity against Gram-Negative Bacteria and In Vivo Efficacy (2014) (35)
The Escherichia coli mutant requiring D-glutamic acid is the result of mutations in two distinct genetic loci (1993) (35)
Microbial genomics and novel antibiotic discovery: new technology to search for new drugs. (2002) (35)
Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XI (1994) (35)
Tobramycin uptake in Escherichia coli is driven by either electrical potential or ATP (1991) (35)
Enhanced tumor control following sequential treatments of photodynamic therapy (PDT) and localized microwave hyperthermia in vivo (1984) (35)
Penicillin-binding proteins are regulated by rpoS during transitions in growth states of Escherichia coli (1994) (34)
An Assay for the Quantitation of Photofrin in Tissues and Fluids (1997) (34)
Lasers and hematoporphyrin derivative in cancer (1983) (33)
Parabolic Quantitative Structure‐Activity Relationships and Photodynamic Therapy: Application of a Three‐Compartment Model with Clearance to the In Vivo Quantitative Structure‐Activity Relationships of a Congeneric Series of Pyropheophorbide Derivatives Used as Photosensitizers for Photodynamic Ther (1999) (33)
Photoradiation therapy. (1984) (33)
Haematoporphyrin derivative photosensitization and gamma-radiation damage interaction in Chinese hamster ovary fibroblasts. (1986) (32)
Competition of beta-lactam antibiotics for the penicillin-binding proteins of Neisseria gonorrhoeae (1981) (32)
Syntheses and photosensitizing activity of porphyrins joined with ester linkages. (1989) (32)
Syntheses and Spectroscopic Studies of Novel Chlorins with Fused Quinoxaline or Benzimidazole Ring Systems and the Related Dimers with Extended Conjugation (2000) (32)
A simple and efficient approach for the synthesis of fluorinated and nonfluorinated octaethylporphyrin-based benzochlorins with variable lipophilicity, their in vivo tumor uptake, and the preliminary in vitro photosensitizing efficacy. (2001) (32)
The Role of the Peripheral Benzodiazepine Receptor in Photodynamic Activity of Certain Pyropheophorbide Ether Photosensitizers: Albumin Site II as a Surrogate Marker for Activity¶ (2002) (32)
UDP-N-acetylmuramyl-L-alanine functions as an activator in the regulation of the Escherichia coli glutamate racemase activity. (1995) (31)
Chlorin-based symmetrical and unsymmetrical dimers with amide linkages: effect of the substituents on photodynamic and photophysical properties (2000) (31)
Photodynamic therapy: status and potential. (1989) (30)
Fast atom bombardment mass spectral analyses of Photofrin II and its synthetic analogs. (1990) (30)
Variability in hematoporphyrin derivative preparations. (1982) (30)
Handbook of Photodynamic Therapy：Updates on Recent Applications of Porphyrin-Based Compounds (2016) (29)
Long wavelength photosensitizers related to chlorins and bacteriochlorins for use in photodynamic therapy (1992) (28)
Novel chlorin–diene building block by enyne metathesis: synthesis of chlorin–fullerene dyads (1999) (28)
Syntheses of new bacteriochlorins and their antitumor activity (1994) (28)
Chemistry of 2,2'-Azobisisobutyramidine Hydrochloride in Aqueous Solution: A Water-soluble Azo Initiator1 (1961) (27)
Of what value is a highly absorbing photosensitizer in PDT? (1991) (27)
Regioselective syntheses of ether-linked porphyrin dimers and trimers related to photofrin-II® (1991) (27)
ABT-773: a new ketolide antibiotic (2001) (27)
Photoradiation Therapy of Malignant Tumors; Role of the Laser (1980) (27)
Photosensitizers related to purpurin-18-N-alkylimides: a comparative in vivo tumoricidal ability of ester versus amide functionalities. (2000) (27)
PHOTOSENSITIZATION BY SYNTHETIC DIPORPHYRINS AND DICHLORINS in vivo AND in vitro (1991) (26)
Purpurinimides as photosensitizers: effect of the presence and position of the substituents in the in vivo photodynamic efficacy. (2000) (26)
SYNTHESIS AND PHOTOSENSITIZING ACTIVITY OF A DI‐PORPHYRIN ETHER (1988) (26)
An overview of the status of photoradiation therapy. (1984) (25)
Substituent effects in tetrapyrrole subunit reactivity and pinacol-pinacolone rearrangements: Vic-dihydroxychlorins and vic-dihydroxybacteriochlorins (1992) (25)
Photodynamic therapy in gynecologic malignancies. (1989) (25)
Photoradiation of rabbit ocular malignant melanoma sensitized with hematoporphyrin derivative. (1984) (25)
PHOTODYNAMIC THERAPY (1993) (25)
CARBON‐14 LABELING AND BIOLOGICAL ACTIVITY OF THE TUMOR‐LOCALIZING DERIVATIVE OF HEMATOPORPHYRIN (1988) (25)
Identification of an inhibitor of the MurC enzyme, which catalyzes an essential step in the peptidoglycan precursor synthesis pathway. (2008) (24)
Porphyrin Photosensitization (1983) (24)
Preliminary clinical data on a new photodynamic therapy photosensitizer: 2-[1-hexyloxyethyl]-2-devinylpyropheophorbide-a (HPPH) for treatment of obstructive esophageal cancer (2000) (24)
New quinolones and the impact on resistance. (2001) (24)
Peptidoglycan biosynthesis in Neisseria gonorrhoeae strains sensitive and intrinsically resistant to beta-lactam antibiotics (1983) (23)
Synthesis of Mono‐ and Di(oxopyri)porphyrins: A New Approach through Ring Enlargement with Diazomethane (1999) (23)
Photoradiation Therapy of Human Tumors (1982) (23)
Alterations in peptidoglycan of Neisseria gonorrhoeae induced by sub-MICs of beta-lactam antibiotics (1987) (23)
Bacteriochlorophyll-a as photosensitizer for photodynamic treatment of transplantable murine tumors (1990) (22)
Optimization of physicochemical properties and safety profile of novel bacterial topoisomerase type II inhibitors (NBTIs) with activity against Pseudomonas aeruginosa. (2014) (22)
Selection and Genetic Characterization of Streptococcus pneumoniae Mutants Resistant to the Des-F(6) Quinolone BMS-284756 (2001) (22)
Photoradiation therapy in the treatment of advanced carcinoma of the trachea and bronchus. (1984) (22)
Tobramycin uptake in Escherichia coli membrane vesicles (1995) (21)
Syntheses and preliminary in vivo photodynamic efficacy of benzoporphyrin derivatives from phylloerythrin and rhodoporphyrin XV methyl esters and aspartyl amides (1996) (21)
PHOTOSENSITIZATION BY DIPORPHYRINS JOINED VIA METHYLENE BRIDGES (1988) (21)
Wittig reactions on photoprotoporphyrin IX: new synthetic models for the special pair of the photosynthetic reaction center. (2000) (20)
SYNTHESES AND SPECTROSCOPIC STUDIES OF SOME NOVEL PORPHYRIN-PYROPHEOPHORBIDE DIMERS AND TRIMERS WITH FIXED DISTANCES (1997) (20)
Chemistry Of Photofrin II And Some New Photosensitizers (1989) (20)
Experimental photodynamic treatment of canine bladder. (1985) (19)
A semi‐empirical approach to the viscosities of polyelectrolyte solutions (1972) (19)
Comparative genome analysis of high-level penicillin resistance in Streptococcus pneumoniae. (2009) (19)
Type II Photolysis of 2-Octanone (1965) (19)
Effect of substituents in OsO4 reactions of metallochlorins regioselective synthesis of isobacteriochlorins and bacteriochlorins (1996) (18)
Syntheses of water-soluble cationic porphyrins and chlorins (1992) (18)
Investigation of human serum albumin (HSA) binding specificity of certain photosensitizers related to pyropheophorbide-a and bacteriopurpurinimide by circular dichroism spectroscopy and its correlation with in vivo photosensitizing efficacy. (2005) (18)
7.18 – Macrolide Antibiotics (2007) (18)
Photodynamic Therapy for Treatment of Cancer (1984) (17)
Synthesis and modification of the peptidoglycan in Neisseria gonorrhoeae (1983) (17)
Isomeric monoacetylmono(1-hydroxyethyl)deuteroporphyrins: syntheses, characterization, and use for the syntheses of regioselectively methyl- and vinyl-deuterated hemins (1990) (17)
Synthesis and Spectroscopic Properties of Novel Benzochlorins Derived from Chlorophyll a (1998) (16)
SOME COMPONENTS OF THE TUMOR‐LOCALIZING FRACTION OF HEMATOPORPHYRIN DERIVATIVE (1990) (16)
Photodynamic Therapy: Mechanisms II (1990) (16)
Syntheses of emeraldin and purpurin-18 analogs as target-specific photosensitizers for photodynamic therapy (1997) (16)
Target-Based Resistance in Pseudomonas aeruginosa and Escherichia coli to NBTI 5463, a Novel Bacterial Type II Topoisomerase Inhibitor (2014) (16)
Optical Methods for Tumor Treatment and Early Diagnosis: Mechanisms and Techniques (1991) (15)
Synthesis and photosensitizing efficacy of isomerically pure bacteriopurpurinimides. (2004) (14)
Structure–Activity Relationship of New Octaethylporphyrin-based Benzochlorins As Photosensitizers for Photodynamic Therapy¶ (2003) (14)
Photodynamic therapy for early stage lung cancer. Preferable to resection? (1992) (13)
Fluorescence detection of premalignant, malignant, and micrometastatic disease using hexylpyropheophorbide (1994) (13)
Comparative in vivo sensitizing efficacy of porphyrin and chlorin dimers joined with ester, ether, carbon–carbon or amide bonds (1996) (13)
Photodynamic therapy for sarcoma pulmonary metastases: a preclinical toxicity study. (2003) (13)
The Escherichia coli Dga (MurI) protein shares biological activity and structural domains with the Pediococcus pentosaceus glutamate racemase (1994) (13)
Synthesis of verdinochlorins: a new class of long-wavelength absorbing photosensitizers (1998) (13)
Application of Ruppert’s reagent in preparing novel perfluorinated porphyrins, chlorins and bacteriochlorins (1999) (12)
Transcriptional Responses of Escherichia coli to a Small-Molecule Inhibitor of LolCDE, an Essential Component of the Lipoprotein Transport Pathway (2016) (12)
NBTI 5463 Is a Novel Bacterial Type II Topoisomerase Inhibitor with Activity against Gram-Negative Bacteria and In Vivo Efficacy (2014) (11)
Syntheses, stability, and tumorcidal activity of porphyrin dimers and trimers with ether linkages (1990) (11)
Efficient syntheses of new classes of regiochemically pure benzoporphyrin derivatives (1993) (11)
ACTIVITY AND PHYSICOCHEMICAL PROPERTIES OF PHOTOFRIN® (1991) (11)
A Simple and Short Synthesis of Divinyl Chlorophyll Derivatives. (1999) (11)
Cyclopentanone ring-cleaved pleuromutilin derivatives. (2007) (11)
Nucleotide sequence changes between Streptococcus pneumoniae R6 and D39 strains determined by an oligonucleotide hybridization DNA sequencing technology. (2007) (10)
Cell-Based Screening in Antibacterial Discovery (2012) (10)
A First Comparative Study of Purpurinimide-based Fluorinated vs. Nonfluorinated Photosensitizers for Photodynamic Therapy¶ (2002) (10)
Hematoporphyrin derivative in the diagnosis and treatment of lung cancer. (1983) (10)
Protection of murine foot tissue and transplantable tumor against Photofrin-II-mediated photodynamic sensitization with WR-2721. (1989) (10)
Photoradiation therapy for bronchogenic cancer. (1982) (9)
Preferential binding and aggregation of rabbit C-reactive protein with arginine-rich proteins. (1991) (9)
CHLOROPHYLL-A DERIVATIVES IN PHOTODYNAMIC THERAPY : EFFECT OF POSITION OF HEPTYL ETHER SIDE-CHAINS ON IN VIVO PHOTOSENSITIZING ACTIVITY (1996) (9)
98th General Meeting of the American Society for Microbiology. May 17-21, 1998; Atlanta, GA. (1998) (9)
Structure of Vinyl Fluoride-Trifluoromethyl Iodide Telomers (1964) (9)
Syntheses of cationic porphyrins and chlorins (1991) (9)
Effect of substituents in directing the formation of benzochlorins and isobacteriochlorins in porphyrin and chlorin systems. (1999) (9)
Antimicrobial resistance - why do we have it and what can we do about it? (2000) (9)
New Syntheses of benzoporphyrin derivatives and analogues for use in photodynamic therapy (1992) (9)
Benzoporphyrin derivatives: synthesis, structure and preliminary biological activity (1994) (9)
Comparison of single- and double-probe measurements of electron temperatures in flames (1972) (8)
Alternate Procedure for Calculating Spin—Spin Coupling Constants by the Perturbation—Variation Method (1967) (8)
Photodynamic therapy: Part II. (1995) (8)
Correct Sorting of Lipoproteins into the Inner and Outer Membranes of Pseudomonas aeruginosa by the Escherichia coli LolCDE Transport System (2019) (8)
A Personal History of Photodynamic Therapy (2007) (7)
Novel antibacterial compounds addressing resistance: patent disclosures 2002 – 2005 (2005) (7)
Synthesis of Novel Benzobacteriopurpurins by Diels-Alder Cycloaddition (1996) (7)
Photopheresis in HIV-1 infected patients utilizing benzoporphyrin derivative (BPD) verteporfin and light. (2008) (7)
The Nature of Amidinium Groups (1962) (7)
Photodynamic Therapy Of Cancer (1989) (7)
Purification of the large ribosomal subunit via its association with the small subunit. (2009) (7)
Cycloaddition reaction on 3-vinylemeraldins: formation of unexpected porphyrins with seven-membered exocyclic ring systems (1999) (6)
The future of photodynamic therapy: is there one? (1990) (6)
Potential Around a Charged Colloidal Sphere (1959) (6)
Microbial Genomics and Drug Discovery (2003) (6)
Allylic Fluorides. Solvolysis of 1,3,5,7,7,7-Hexafluoro-1-heptene (1964) (6)
Syntheses of new porphyrin-type photosensitizers for photodynamic therapy (1992) (5)
Electrical Properties of Ice. I. Dielectric Relaxation in Pure Ice (1965) (5)
Photodynamic Therapy (PDT) and Clinical Applications (2003) (5)
Photoradiation of malignant tumors (1977) (5)
Remarks on the use of approximate wavefunctions for the second-order perturbation energy. (1966) (5)
Thermolysis of vic-dihydroxybacteriochlorins: a new approach for the synthesis of chlorin-chlorin and chlorin-porphyrin dimers. (1999) (5)
Syntheses and unusual spectroscopic properties of novel ketobacteriopurpurins (1996) (5)
A novel synthetic route to fused propenochlorin and benzochlorin photodynamic therapy probes. (2002) (5)
Why are there no new antibiotics? (1998) (5)
Microbial genomics and drug discovery: exploring innovative routes of drug discovery in the postgenomic era. (2006) (5)
Antibacterial Agents, Quinolones (2002) (4)
The Comparison of Flooded, Gelled and Immobilized Lead-Acid Batteries (1984) (4)
Excited-State Coordination Chemistry: A New Quenching Mechanism (1998) (4)
Genomics-Based Approaches to Novel Antimicrobial Target Discovery (2003) (4)
Antibacterial Pleuromutilin Derivatives based on Alternate Core Structures:Arigoni and Birch Chemistry Revisited (2008) (4)
Synthetic approaches to long-wavelength photosensitizers for photodynamic therapy (1991) (4)
Photosensitizers Related to Purpurin‐18‐N‐alkylimides: A Comparative in vivo Tumoricidal Ability of Ester versus Amide Functionalities. (2000) (4)
Optical methods for in-vivo pharmacokinetics (Invited Paper) (1992) (4)
Structure–Activity Relationship of New Octaethylporphyrin‐based Benzochlorins As Photosensitizers for Photodynamic Therapy ¶ (2003) (4)
Study of factors mediating effect of photodynamic therapy on bladder in canine bladder model. (1988) (4)
Potential new photosensitizers for photodynamic therapy (1990) (4)
Novel Antibacterial Targets/Identification of New Targets by Comparative Genomics (2012) (4)
A First Comparative Study of Purpurinimide‐based Fluorinated vs. Nonfluorinated Photosensitizers for Photodynamic Therapy ¶ (2002) (4)
Regioselective Syntheses of Ether‐Linked Porphyrin Dimers and Trimers Related to Photofrin‐II. (1992) (3)
Off-Label Management of Primary and Metastatic Endobronchial Tumors With Photodynamic Therapy (2004) (3)
Antibacterial Drug Discovery & Development Summit (2004) (3)
Syntheses of Hematoporphyrin Dimers and Trimers with Ether Linkages. (1989) (3)
Transcriptional Responses of Pseudomonas aeruginosa to Inhibition of Lipoprotein Transport by a Small Molecule Inhibitor (2020) (3)
Regioselective syntheses and some in vivo properties of “benzochlorin” analogues prepared from methyl 9-deoxymesopyropheophorbide (1995) (3)
Naturally Occurring Prenatal Infection with Toxocara canis in Wolf Pups (Canis lupus) Born in Captivity, with Notes on Hookworm Infection (1979) (3)
The Directors' Handbook (2006) (3)
Improved photosensitizers for photodynamic therapy (1992) (3)
Optical methods for tumor treatment and detection : mechanisms and techniques in photodynamic therapy IX : 22-23 January 2000, San Jose, California (2000) (3)
Syntheses of porphyrin and chlorin dimers for photodynamic therapy (1991) (2)
Photoradiation therapy. Optimum wavelength for in vivo activation of hematoporphyrin derivative with laser irradiation. Abstr. (1978) (2)
BINDING REACTIVITY OF RABBIT CRP FOR POLYCATIONS (1982) (2)
Photodynamic Therapy: Its Role in Cancer Therapy (1992) (2)
Clinical Applications of Photodynamic Therapy (2003) (2)
Wittig Reaction on Chlorin: Formation of an Unexpected Chlorin−Spirochlorin Dimer with Significant Overlap between the π Electron System (1998) (2)
Peptide-Induced Ion Transport in Synthetic and Biological Membranes (1971) (2)
A method to assay penicillin-binding proteins. (2008) (2)
INVITED REVIEW: DEVELOPMENT AND APPLICATION OF THE HIGH INTENSITY CONVECTIVE ELECTRIC ARC (1982) (2)
The Roswell Park History of PDT : 1972 to the Present A PeRsonAl PeRsPecTive (2008) (2)
Photopheresis in HIV-1 Infected Patients (Pt) Using Benzoporphyrin Derivative (BPD-MA) Induces Apoptosis in CD4 Cells, Increases Cytolytic T-Cell Activity, Intracellular Expression of Chemokines, and Decreases HIV Infectivity and Viral Load. (2006) (1)
Effect of fluorine on photoelimination reactions in ketones (1968) (1)
Novel Chlorin—Diene Building Block by Enyne Metathesis: Synthesis of Chlorin—Fullerene Dyads. (2000) (1)
Cellular and tissue repair of photodynamic damage. Abstr. (1979) (1)
LiOH Promoted Allomerization of Pyropheophorbide a. A Convenient Synthesis of 132-Oxopyropheophorbide a and Its Unusual Enolization. (1998) (1)
Application of Ruppert′s Reagent in Preparing Novel Perfluorinated Porphyrins, Chlorins and Bacteriochlorins. (1999) (1)
A phase I/II study of photodynamic therapy (PDT) using HPPH for the treatment of Barrett's and precancerous lesions of the esophagus. (2010) (1)
Transannular peroxides as radiation sensitizers. (1973) (1)
Point fluorescence measurements of transformed tissues using 2-[1-hexyloxyethel]-2-devinyl pyropheophorbide-a (1994) (1)
Photopheresis in HIV-1 Infected Patients Utilizing (Benzoporphyrin Derivative Verteporfin/BPD-MA) and Light. (2007) (1)
Controlling the New Inflation (1981) (1)
Use of hematoporphyrin in photodynamic therapy. (1991) (1)
Efficient Syntheses of New Classes of Regiochemically Pure Benzoporphyrin Derivatives. (2010) (1)
Determination of ( 3 H ]-and ( 14 CjHematoporphyrinDerivative Distribution in Malignant and Normal Tissue 1 (2006) (1)
Purified hematoporphyrin derivative for the diagnosis and treatment of tumors (1984) (1)
Pharmacogenomics—Is there a role in antibiotic therapy? (2002) (1)
Editorial overview: Antimicrobials: fighting bacterial infections in the 21st century-thinking outside of the box. (2016) (1)
Bacterial “Genes-to-Screens” in the Post-Genomic Era (2002) (1)
Syntheses of New Porphyrin‐Type Photosensitizers for Photodynamic Therapy (1992) (1)
Targets, targets everywhere--so where are the new antibacterial drugs? (2000) (1)
Syntheses of Water‐Soluble Cationic Porphyrins and Chlorins. (1992) (1)
Effect of substituents in directing the regioselective synthesis of novel pyridinium chlorins (2000) (1)
Effect of meso-Substituents on the Osmium Tetraoxide Reaction and Pinacol—Pinacolone Rearrangement of the Corresponding vic-Dihydroxyporphyrins. (2001) (1)
Photopheresis in HIV-1 Infected Patients (pt) using Benzoporphyrin Derivative (BPD-MA) Induces Apoptosis in CD4 Cells, Increases Intracellular Expression of Chemokines and Decreases HIV Infectivity and Viral Load. (2004) (1)
“Photodynamic therapy in gastrointestinal cancer” (1992) (1)
Chapter 10. The prospects for microbial genomics providing novel, exploitable, antibacterial targets (2002) (1)
Synthesis of Novel Benzobacteriopurpurins by Diels‐Alder Cycloaddition. (1997) (1)
Synthetic approaches to long-wavelength photosensitizers for photodynamic therapy and their preliminary biological activity (1995) (0)
Cycloaddition Reaction on 3‐Vinylemeraldins: Formation of Unexpected Porphyrins with Seven‐Membered Exocyclic Ring Systems. (1999) (0)
NBTI 5463 is a novel bacterial type II topoisomerase inhibitor with Gram-6 negative antibacterial activity and in vivo efficacy (2014) (0)
Chairman's Summing‐Up (2007) (0)
Chlorin-Based Symmetrical and Unsymmetrical Dimers with Amide Linkages: Effect of the Substituents on Photodynamic and Photophysical Properties. (2000) (0)
Effect of 2450 MilliHertz Irradiation on Survival of Cells Containing Photofrin® II (1989) (0)
Substitution of the gene LolCDE from Pseudomonas aeruginosa into Escherichia coli (2016) (0)
Target-Based Resistance in Pseudomonas aeruginosa and Escherichia coli to NBTI 1 5463 , a Novel Bacterial Type II Topoisomerase Inhibitor 2 3 4 5 (2014) (0)
And chlorin bakteriochlorinbaserede aminophenyl DTPA conjugates for MR contrast media and radiopharmaceuticals (2000) (0)
Australian Bird Drawings (1982) (0)
The future of photodynamic therapy (1993) (0)
Quantification of photodynamic damage in a murine tumor. Abstr. (1976) (0)
Tobramycin Uptake inEscherichia coliMembrane Vesicles (1995) (0)
ChemInform Abstract: A Novel Synthetic Route to Fused Propenochlorin (I) and Benzochlorin (II) Photodynamic Therapy Probes. (2002) (0)
Optical methods for tumor treatment and detection : mechanisms and techniques in photodynamic therapy X : 20-21 January 2001, San Jose, USA (1992) (0)
THE COMPARISONOF FLOODED,GELLED AND IMMOBILIZEDLEAD-ACID BATTERIES (1964) (0)
EBS Leasing Primer: The Educator's Perspective (2010) (0)
Purified hematoporfyrinderivat for the diagnosis and treatment of tumors, as well as process for the preparation of the purified derivatives and compositions containing them (1984) (0)
Photodynamic therapy. (1985) (0)
Photodynamic Therapy in Lung Cancer (2000) (0)
Efficacy of pyropheophorbide-a-hexyl ether for photodynamic therapy of rat 9L gliosarcoma (1993) (0)
Structural and functional changes in the cell envelope of escherichia coli Br induced by inhibition of DNA synthesis (1978) (0)
The Role of the Peripheral Benzodiazepine Receptor in Photodynamic Activity of Certain Pyropheophorbide Ether Photosensitizers: Albumin Site II as a Surrogate Marker for Activity ¶ (2002) (0)
Synthesis of Verdinochlorins: A New Class of Long‐Wavelength Absorbing Photosensitizers. (1998) (0)
Production of Fine Powders for Permanent Magnets Using a D.C. Arc Plasma (1985) (0)
Efficient Synthesis of Porphyrin Dimers with Carbon-Carbon Linkages. (1990) (0)
Photodynamic therapy for treatment of cancer in pet dogs and cats (1985) (0)
What will genomics bring to the finish line? (2001) (0)
Proceedings of photodynamic therapy--mechanisms II : 16-17 January 1990, Los Angeles, California (1990) (0)
Proceedings of optical methods for tumor treatment and early diagnosis : mechanisms and techniques : 23-25 January 1991, Los Angeles, California (1991) (0)
Photodynamic therapy : mechanisms, 19-20 January 1989, Los Angeles, California (1989) (0)
Photodynamic therapy for AIDS-related cutaneous Kaposis sarcoma (1995) (0)
Kinetics of basic hydrolysis of a homologous series of substituted lactones (1959) (0)
Faculty Opinions recommendation of Crystal structure of the oxazolidinone antibiotic linezolid bound to the 50S ribosomal subunit. (2008) (0)
Drug and method of its manufacture and use for treating tumors. (1985) (0)
The photosensitive medium. (1989) (0)
United States Patent ( 19 ) Dougherty et al . 54 USE OF PURIFIED HEMATOPORPHYRIN TRMERS IN PHOTODYNAMIC THERAPY (2017) (0)
Dimeres et trimeres d'hematoporphyrine purifies utiles en therapie photodynamique (1989) (0)
A composition which comprises an active ingredient which is lysfölsom, and a method for producing such substance mixture (1985) (0)
Proceedings of optical methods for tumor treatment and detection : mechanisms and techniques in photodynamic therapy III : 22-23 January 1994, Los Angeles, California (1994) (0)
Controlling the New Inflation. (1982) (0)
Photoradiation therapy of animal tumors. Abstr. (1975) (0)
Drugs and method for its manufacture and application to tumor treatment. (1985) (0)
The Ohio State University Commencement Address by Thomas J. Dougherty, Autumn 1995 (1995) (0)
Efficacy In Vivo against Gram-Negative Bacteria and Topoisomerase Inhibitor with Activity NBTI 5463 Is a Novel Bacterial Type II (2014) (0)

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