Thomas J. Kelly
#34,299
Most Influential Person Now
American biologist
Thomas J. Kelly 's AcademicInfluence.com Rankings
Thomas J. Kelly biology Degrees
Biology
#1295
World Rank
#2199
Historical Rank
#660
USA Rank
Molecular Biology
#281
World Rank
#286
Historical Rank
#115
USA Rank
Cell Biology
#380
World Rank
#390
Historical Rank
#64
USA Rank
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Biology
Thomas J. Kelly 's Degrees
- PhD Biology University of California, Berkeley
- Masters Biology University of California, Berkeley
- Bachelors Biology University of California, Berkeley
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Why Is Thomas J. Kelly Influential?
(Suggest an Edit or Addition)According to Wikipedia, Thomas J. Kelly is an American cancer researcher whose work focuses on the molecular mechanisms of DNA replication. Kelly is director of the Sloan-Kettering Institute, the basic research arm of the Memorial Sloan-Kettering Cancer Center. He holds the Center's Benno C. Schmidt Chair of Cancer Research.
Thomas J. Kelly 's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- A cellular DNA-binding protein that activates eukaryotic transcription and DNA replication (1987) (734)
- The proline-rich transcriptional activator of CTF/NF-I is distinct from the replication and DNA binding domain (1989) (661)
- Differentiation-induced gene expression in 3T3-L1 preadipocytes: CCAAT/enhancer binding protein interacts with and activates the promoters of two adipocyte-specific genes. (1989) (550)
- A restriction enzyme from Hemophilus influenzae: II. Base sequence of the recognition site (1970) (484)
- The fission yeast cdc18 + gene product couples S phase to START and mitosis (1993) (465)
- Simian virus 40 DNA replication in vitro. (1984) (455)
- Regulation of human thymidine kinase during the cell cycle. (1988) (437)
- Regulation of chromosome replication. (2000) (435)
- Purification and characterization of replication protein A, a cellular protein required for in vitro replication of simian virus 40 DNA. (1988) (421)
- Animal virus DNA replication. (1989) (420)
- Interaction of DNA polymerase alpha‐primase with cellular replication protein A and SV40 T antigen. (1992) (333)
- Differentiation-induced gene expression in 3T3-L1 preadipocytes. Characterization of a differentially expressed gene encoding stearoyl-CoA desaturase. (1988) (329)
- Differentiation-induced gene expression in 3T3-L1 preadipocytes. A second differentially expressed gene encoding stearoyl-CoA desaturase. (1989) (310)
- Sequence-independent DNA binding and replication initiation by the human origin recognition complex. (2003) (300)
- Expression of specific mRNAs during adipose differentiation: identification of an mRNA encoding a homologue of myelin P2 protein. (1984) (270)
- Evidence for an increase in transcription of specific mRNAs during differentiation of 3T3-L1 preadipocytes. (1985) (261)
- Roles of DNA topoisomerases in simian virus 40 DNA replication in vitro. (1987) (247)
- The fission yeast homologue of Orc4p binds to replication origin DNA via multiple AT-hooks. (1999) (239)
- Adenovirus DNA replication in vitro. (1979) (226)
- Use of Nondefective Adenovirus-Simian Virus 40 Hybrids for Mapping the Simian Virus 40 Genome (1973) (223)
- Purification of nuclear factor I by DNA recognition site affinity chromatography. (1986) (208)
- Initiation of simian virus 40 DNA replication in vitro: large-tumor-antigen- and origin-dependent unwinding of the template. (1987) (199)
- The linear ubiquitin assembly complex (LUBAC) is essential for NLRP3 inflammasome activation (2014) (196)
- The ATM homologue MEC1 is required for phosphorylation of replication protein A in yeast. (1996) (195)
- Integrated simian virus 40 sequences in transformed cell DNA: analysis using restriction endonucleases. (1976) (194)
- Regulation of the replication initiator protein p65cdc18 by CDK phosphorylation. (1997) (189)
- Effects of T antigen and replication protein A on the initiation of DNA synthesis by DNA polymerase alpha-primase (1991) (188)
- The structure of replicating adenovirus 2 DNA molecules (1977) (185)
- An essential Saccharomyces cerevisiae single‐stranded DNA binding protein is homologous to the large subunit of human RP‐A. (1990) (184)
- Identification of cellular proteins required for simian virus 40 DNA replication. (1989) (174)
- Simian virus 40 DNA replication in vitro: specificity of initiation and evidence for bidirectional replication (1985) (172)
- Structure of Replicating Simian Virus 40 Deoxyribonucleic Acid Molecules (1971) (161)
- The DNA-activated protein kinase is required for the phosphorylation of replication protein A during simian virus 40 DNA replication. (1994) (159)
- Expression of the HsOrc1 gene, a human ORC1 homolog, is regulated by cell proliferation via the E2F transcription factor (1996) (156)
- Transcription factor OTF-1 is functionally identical to the DNA replication factor NF-III. (1988) (156)
- Adenovirus DNA replication in vitro: characterization of a protein covalently linked to nascent DNA strands. (1980) (154)
- Transcriptional activator nuclear factor I stimulates the replication of SV40 minichromosomes in vivo and in vitro (1989) (149)
- Genetic analysis of an ARS element from the fission yeast Schizosaccharomyces pombe. (1995) (148)
- cdc18+ regulates initiation of DNA replication in Schizosaccharomyces pombe. (1996) (145)
- SV40 DNA replication. (1988) (145)
- Assembly of the Human Origin Recognition Complex* (2001) (142)
- Cell cycle regulation of thymidine kinase: residues near the carboxyl terminus are essential for the specific degradation of the enzyme at mitosis (1991) (139)
- DNA replication origins in the Schizosaccharomyces pombe genome. (2005) (137)
- Functional organization of the simian virus 40 origin of DNA replication (1986) (134)
- Purification of Hsk1, a Minichromosome Maintenance Protein Kinase from Fission Yeast* (1998) (131)
- Reconstitution of simian virus 40 DNA replication with purified proteins. (1990) (128)
- Sequence-specific interactions between cellular DNA-binding proteins and the adenovirus origin of DNA replication (1987) (126)
- Characterization of a cDNA encoding the 70-kDa single-stranded DNA-binding subunit of human replication protein A and the role of the protein in DNA replication. (1991) (124)
- The role of the 70 kDa subunit of human DNA polymerase alpha in DNA replication. (1993) (122)
- A restriction enzyme from Hemophilus influenzae. II. (1970) (121)
- An intermediate in the replication of bacteriophage T7 DNA molecules. (1969) (120)
- Activation of SV40 DNA replication in vitro by cellular protein phosphatase 2A. (1989) (110)
- Multiple tandemly repeated binding sites for cellular nuclear factor 1 that surround the major immediate-early promoters of simian and human cytomegalovirus (1987) (109)
- Structure and function of the adenovirus origin of replication (1984) (107)
- Overlapping octamer and TAATGARAT motifs in the VF65-response elements in herpes simplex virus immediate-early promoters represent independent binding sites for cellular nuclear factor III (1989) (106)
- Rum1 and Cdc18 link inhibition of cyclin-dependent kinase to the initiation of DNA replication in Schizosaccharomyces pombe. (1996) (100)
- Phosphorylation of the replication protein A large subunit in the Saccharomyces cerevisiae checkpoint response. (2000) (98)
- Mapping of Simian Virus 40 Early Functions on the Viral Chromosome (1973) (96)
- Two-stage mechanism for activation of the DNA replication checkpoint kinase Cds1 in fission yeast. (2006) (96)
- Orp1, a member of the Cdc18/Cdc6 family of S-phase regulators, is homologous to a component of the origin recognition complex. (1995) (96)
- Cell cycle regulation of Dfp1, an activator of the Hsk1 protein kinase. (1999) (93)
- Tissue specific expression of p422 protein, a putative lipid carrier, in mouse adipocytes. (1985) (90)
- Identification and characterization of a single-stranded DNA-binding protein from the archaeon Methanococcus jannaschii. (1998) (89)
- Initiation of adenovirus DNA replication: detection of covalent complexes between nucleotide and the 80-kilodalton terminal protein (1982) (86)
- Structure of the linkage between adenovirus DNA and the 55,000 molecular weight terminal protein. (1981) (86)
- Expression of the differentiation-induced gene for fatty acid-binding protein is activated by glucocorticoid and cAMP. (1988) (85)
- Processing of the adenovirus terminal protein (1981) (84)
- Human cytosolic thymidine kinase. Purification and physical characterization of the enzyme from HeLa cells. (1988) (83)
- The primary structure of the 32-kDa subunit of human replication protein A. (1990) (83)
- The human homologous pairing protein HPP-1 is specifically stimulated by the cognate single-stranded binding protein hRP-A. (1991) (82)
- Eukaryotic DNA replication: viral and plasmid model systems. (1982) (79)
- Adenovirus origin of DNA replication: sequence requirements for replication in vitro (1987) (79)
- Regulation of DNA replication in vitro by the transcriptional activation domain of GAL4-VP16. (1992) (77)
- sud1(+) targets cyclin-dependent kinase-phosphorylated Cdc18 and Rum1 proteins for degradation and stops unwanted diploidization in fission yeast. (1998) (72)
- Mechanism of regulation of the 422(aP2) gene by cAMP during preadipocyte differentiation. (1989) (71)
- Mechanism of activation of simian virus 40 DNA replication by protein phosphatase 2A (1992) (71)
- Purification and characterization of nuclear factor III (origin recognition protein C), a sequence-specific DNA binding protein required for efficient initiation of adenovirus DNA replication. (1988) (70)
- An unusual spliced herpes simplex virus type 1 transcript with sequence homology to Epstein-Barr virus DNA (1985) (70)
- Shedding Light on the DNA Damage Checkpoint (2007) (68)
- Arrangement of nucleotide sequences in adeno-associated virus DNA. (1973) (68)
- Identification of autonomously replicating sequence (ARS) elements in eukaryotic cells. (1997) (66)
- Redundant control of rereplication in fission yeast (2001) (65)
- Adenovirus DNA replication in vitro: origin and direction of daughter strand synthesis. (1979) (63)
- Requirement for two DNA polymerases in the replication of simian virus 40 DNA in vitro. (1989) (61)
- Letter: Visualization of the inverted terminal repetition in adeno-associated virus DNA. (1974) (58)
- Postreplication gaps at UV lesions are signals for checkpoint activation (2010) (56)
- Cyclin-dependent kinase and initiation at eukaryotic origins: a replication switch? (1997) (55)
- The Schizosaccharomyces pombe rad11+ gene encodes the large subunit of replication protein A (1997) (53)
- UV irradiation induces a postreplication DNA damage checkpoint (2006) (51)
- Purification and characterization of the Schizosaccharomyces pombe origin recognition complex: interaction with origin DNA and Cdc18 protein. (2002) (50)
- The fate of parental nucleosomes during SV40 DNA replication. (1992) (49)
- Interaction of the S phase regulator cdc18 with cyclin-dependent kinase in fission yeast. (1997) (47)
- Protein phosphatase 2A dephosphorylates simian virus 40 large T antigen specifically at residues involved in regulation of DNA-binding activity (1991) (47)
- A colinear map relating the simian virus 40 (SV40) DNA segments of six adenovirus-SV40 hybrids to the DNA fragments produced by restriction endonuclease cleavage of SV40 DNA. (1974) (46)
- Adenovirus DNA Replication (1984) (44)
- Purification of replication protein C, a cellular protein involved in the initial stages of simian virus 40 DNA replication in vitro. (1989) (43)
- Isolation of cell cycle fractions by counterflow centrifugal elutriation. (1990) (43)
- Initiation of viral DNA replication. (1988) (42)
- Identification of eukaryotic DNA replication proteins using simian virus 40 in vitro replication system. (1995) (42)
- Cloning, overexpression, and genomic mapping of the 14-kDa subunit of human replication protein A. (1993) (39)
- High-affinity binding site for a specific nuclear protein in the human IgM gene (1985) (37)
- Simian virus 40 integration site in an adenovirus 7-simian virus 40 hybrid DNA molecule. (1971) (37)
- In vitro complementation as an assay for purification of adenovirus DNA replication proteins. (1983) (36)
- Structure of two adenovirus-simian virus 40 hybrids which contain the entire SV40 genome. (1974) (36)
- DNA Polymerase III: Running Rings around the Fork (1996) (33)
- Multiple Mechanisms Contribute to Schizosaccharomyces pombe Origin Recognition Complex-DNA Interactions* (2008) (32)
- Dynamics of DNA replication in a eukaryotic cell (2019) (32)
- DNA replication: Controlling initiation during the cell cycle (1996) (32)
- Rearrangements of host and viral DNA in mouse cells transformed by simian virus 40. (1984) (28)
- Genetic analysis of the human thymidine kinase gene promoter (1986) (28)
- Evolutionary relationships of the primate papovaviruses: base sequence homology among the genomes of simian virus 40, stump-tailed macaque virus, and SA12 virus (1979) (27)
- Characterization of the mouse insulin receptor gene promoter. (1989) (27)
- High-affinity binding site for a specific nuclear protein in the human IgM gene (1985) (27)
- Autoinhibition and Autoactivation of the DNA Replication Checkpoint Kinase Cds1 (2009) (26)
- Coupling DNA replication to the cell cycle. (1993) (25)
- S. pombe replication protein Cdc18 (Cdc6) interacts with Swi6 (HP1) heterochromatin protein (2011) (24)
- 1 Mechanisms for Replicating DNA (1996) (21)
- Structure of integrated simian virus 40 DNA in transformed mouse cells. (1980) (20)
- Herpes simplex virus downregulation of secretory leukocyte protease inhibitor enhances human papillomavirus type 16 infection. (2016) (18)
- High-resolution genomic mapping of the three human replication protein A genes (RPA1, RPA2, and RPA3). (1994) (18)
- A Restriction Enzyme from Hemophilus influenzae II. Base Sequence of the Recognition Site (1989) (17)
- Structure of the DNA of the Adenovirus 7-Simian Virus 40 Hybrid, E46+, by Electron Microscopy (1975) (15)
- Identification of two distinct regions within the adenovirus minimal origin of replication that are required for adenovirus type 4 DNA replication in vitro (1991) (13)
- Mutations in the thymidine kinase gene that allow expression of the enzyme in quiescent (G0) cells. (1991) (13)
- Electron microscope study of the base sequence homology between simian virus 40 and human papovavirus BK (1978) (12)
- Regulation of the replication initiator protein p65 by CDK phosphorylation (1997) (11)
- Increase in translatable mRNA for mitochondrial pyruvate carboxylase during differentiation of 3T3 preadipocytes. (1981) (11)
- Geminin Inhibits a Late Step in the Formation of Human Pre-replicative Complexes* (2014) (11)
- Controlling initiation during the cell cycle. DNA replication. (1996) (10)
- Duplication of DNA in eukaryotic cells (2006) (9)
- Enzymatic methods for sequence analysis applied to DNA restriction and methylation sites. (1974) (8)
- Coordination of DNA damage tolerance mechanisms with cell cycle progression in fission yeast (2015) (8)
- Historical Perspective of Eukaryotic DNA Replication. (2017) (7)
- DNA Replication in S. pombe (2004) (7)
- Effect of sucrose on intestinal very low-density lipoprotein production. (1980) (7)
- DNA replication in mammalian cells: insights from the SV40 model system. (1989) (7)
- Replication and Transcription: Silence of the ORCs (1994) (6)
- Schizosaccharomyces pombe Noc3 Is Essential for Ribosome Biogenesis and Cell Division but Not DNA Replication (2008) (6)
- Erratum: Characterization of a cDNA encoding the 70-kDa single-stranded DNA-binding subunit of human replication protein A and the role of the protein in DNA replication (Journal of Biological Chemistry (1991) 266 (12090-12098)) (1993) (4)
- Mechanisms for Replicating DNA (2005) (4)
- Eukaryotic DNA replication (1988) (4)
- IN VITRO REPLICATION OF ADENOVIRUS DNA (1979) (3)
- SV40 DNA Replication with Purified Proteins: Functional Interactions Among the Initiation Proteins (1992) (3)
- Purification and Characterization of theSchizosaccharomyces pombe Origin Recognition Complex (2002) (2)
- Abstracts of papers presented at the Sixth Cold Spring Harbor Meeting on Cancer Cells Eukaryotic DNA Replication, September 2-September 6, 1987 (1987) (2)
- Discovery and Validation of a Novel Class of Small Molecule Inhibitors of the CDC7 Kinase: Modulation of Tumor Cell Growth in Vitro and In Vivo. (2009) (2)
- Regulation ofDNA replication invitro bythetranscriptional activation domainofGAL4-VP16 (1992) (2)
- Small Molecule Inhibition of Cdc7, a Key Cell Cycle Regulator and Novel Therapeutic Target, Successfully Inhibits Leukemia Cell Growth in Vitro and in Vivo (2008) (1)
- Replication of adenovirus and SV40 chromosomes in vitro. (1987) (1)
- Identification ofTwoDistinct Regions within theAdenovirus Minimal Origin ofReplication ThatAreRequired for Adenovirus Type4DNA Replication InVitro (1991) (1)
- polymerase alpha-primase. on the initiation of DNA synthesis by DNA Effects of T antigen and replication protein A (2013) (0)
- Abstracts of papers presented at the 1999 Meeting on Eukaryotic DNA Replication, September 15-September 19, 1999 (1997) (0)
- Abstracts of papers presented at the 2001 Meeting on Eukaryotic DNA Replication, September 5-September 9, 2001 (2001) (0)
- TRANSIENTLY EXPRESSED PROTEINS IN MYOCARDIAL HYPERTROPHY (1984) (0)
- Targeting the Cell Cycle Regulated Cdc7 Kinase Pathway as a Novel Therapeutic Approach for Hematologic Malignancies (2014) (0)
- Mechanism of regulation of the 422 ( aP 2 ) gene by cAMP during preadipocyte differentiation ( 3 T 3L 1 cells / adipocyte / promoter / activator protein 1 / transfection ) (2003) (0)
- Abstracts of papers presented at the 1995 Meeting on Eukaryotic DNA Replication, September 6-September 10, 1995 (1995) (0)
- DNA Replication (2019) (0)
- Regulation of expression of specific mRNAs during differentiation of 3T3-L1 cells (1985) (0)
- Adenovirus DNA replication in vitro ( eukaryotic DNA replication ) (1999) (0)
- to coordinate DNA replication with other events in the cell cycle and to control initiation of DNA synthesis in both space and time (2007) (0)
- Simian virus 40 DNA replication in vitro ( eukaryotic DNA replication / simian virus 40 large tumor antigen / simian virus 40 origin of replication / Dpn I replication assay ) (0)
- DNA Synthesis by DNA Polymerase oL-Primase (2003) (0)
- 293 Inhibition of the cell cycle regulated Cdc7 kinase pathway is an efficacious therapeutic approach for hematologic malignancies and solid tumors (2014) (0)
- Abstracts of papers presented at the 1989 Meeting on Eukaryotic DNA Replication, August 30-September 3, 1989 (1989) (0)
- High throughput profiling of leukemia and lymphoma cell lines using small molecules: In search of conserved and novel chemical scaffold signatures effective for specific diseases (2006) (0)
- Abstracts of papers presented at the 1993 Meeting on Eukaryotic DNA Replication, September 8-September 12, 1993 (1993) (0)
- DNA replication and recombination : proceedings of a UCLA symposium held at Park City, Utah, March 16-23, 1986 (1987) (0)
- Table of Contents (1993) (0)
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