Thomas J. Silhavy
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American microbiologist
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Biology
Thomas J. Silhavy's Degrees
- PhD Microbiology Princeton University
- Masters Microbiology Princeton University
- Bachelors Biology Princeton University
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Why Is Thomas J. Silhavy Influential?
(Suggest an Edit or Addition)According to Wikipedia, Thomas J. Silhavy is the Warner-Lambert Parke-Davis Professor of molecular biology at Princeton University. Silhavy is a bacterial geneticist who has made fundamental contributions to several different research fields. He is best known for his work on protein secretion, membrane biogenesis, and signal transduction. Using Escherichia coli as a model system, his lab was the first to isolate signal sequence mutations, identify a component of cellular protein secretion machinery, discover an integral membrane component of the outer membrane assembly machinery, and to identify and characterize a two-component regulatory system. Current work in his lab is focused on the mechanisms of outer membrane biogenesis and the regulatory systems that sense and respond to envelope stress and trigger the developmental pathway that allows cells to survive starvation. He is the author of more than 200 research articles and three books.
Thomas J. Silhavy's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Experiments With Gene Fusions (1984) (2919)
- The bacterial cell envelope. (2010) (2503)
- Identification of a Multicomponent Complex Required for Outer Membrane Biogenesis in Escherichia coli (2005) (697)
- Advances in understanding bacterial outer-membrane biogenesis (2006) (459)
- Defining the roles of the periplasmic chaperones SurA, Skp, and DegP in Escherichia coli. (2007) (453)
- Two-component signal transduction (1995) (448)
- Periplasmic stress and ECF sigma factors. (2001) (410)
- Surface sensing and adhesion of Escherichia coli controlled by the Cpx-signaling pathway (2002) (393)
- An ABC transport system that maintains lipid asymmetry in the Gram-negative outer membrane (2009) (381)
- Structure and Function of an Essential Component of the Outer Membrane Protein Assembly Machine (2007) (358)
- The Cpx two-component signal transduction pathway of Escherichia coli regulates transcription of the gene specifying the stress-inducible periplasmic protease, DegP. (1995) (332)
- Suppressor mutations that restore export of a protein with a defective signal sequence (1981) (330)
- From acids to osmZ: multiple factors influence synthesis of the OmpF and OmpC porins in Escherichia coli (1996) (326)
- Sensing external stress: watchdogs of the Escherichia coli cell envelope. (2005) (317)
- Identification of a protein complex that assembles lipopolysaccharide in the outer membrane of Escherichia coli. (2006) (316)
- β-Barrel membrane protein assembly by the Bam complex. (2011) (315)
- YfiO stabilizes the YaeT complex and is essential for outer membrane protein assembly in Escherichia coli (2006) (303)
- CpxP, a Stress-Combative Member of the Cpx Regulon (1998) (298)
- Genetic analysis of protein export in Escherichia coli K12. (1985) (297)
- The ompB locus and the regulation of the major outer membrane porin proteins of Escherichia coli K12. (1981) (297)
- Lipoprotein SmpA is a component of the YaeT complex that assembles outer membrane proteins in Escherichia coli (2007) (293)
- Chemical Conditionality A GeneticStrategy to Probe Organelle Assembly (2005) (290)
- The sigma(E) and the Cpx signal transduction systems control the synthesis of periplasmic protein-folding enzymes in Escherichia coli. (1997) (284)
- Transduction of envelope stress in Escherichia coli by the Cpx two-component system (1997) (278)
- The E. coli ffh gene is necessary for viability and efficient protein export (1992) (271)
- Lipopolysaccharide transport and assembly at the outer membrane: the PEZ model (2016) (268)
- Phosphorylation and dephosphorylation of a bacterial transcriptional activator by a transmembrane receptor. (1989) (266)
- The response regulator SprE controls the stability of RpoS. (1996) (264)
- Genetic analysis of the ompB locus in Escherichia coli K-12. (1981) (263)
- Uses of lac fusions for the study of biological problems. (1985) (261)
- Genetic Evidence for Parallel Pathways of Chaperone Activity in the Periplasm of Escherichia coli (2001) (259)
- The chaperone‐assisted membrane release and folding pathway is sensed by two signal transduction systems (1997) (254)
- Maltose Transport in Escherichia coli K12 (1976) (250)
- Imp/OstA is required for cell envelope biogenesis in Escherichia coli (2002) (247)
- Transport of lipopolysaccharide across the cell envelope: the long road of discovery (2009) (242)
- The Cpx Envelope Stress Response Is Controlled by Amplification and Feedback Inhibition (1999) (241)
- Use of gene fusion to study secretion of maltose-binding protein into Escherichia coli periplasm (1979) (241)
- Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli (2008) (237)
- Overproduction of NlpE, a new outer membrane lipoprotein, suppresses the toxicity of periplasmic LacZ by activation of the Cpx signal transduction pathway (1995) (229)
- Functional Analysis of the Protein Machinery Required for Transport of Lipopolysaccharide to the Outer Membrane of Escherichia coli (2008) (224)
- Targeting and assembly of periplasmic and outer-membrane proteins in Escherichia coli. (1998) (220)
- Mechanisms of protein localization. (1983) (217)
- Signal Detection and Target Gene Induction by the CpxRA Two-Component System (2003) (212)
- Genetic analysis of protein export in Escherichia coli. (1983) (198)
- EnvZ controls the concentration of phosphorylated OmpR to mediate osmoregulation of the porin genes. (1991) (193)
- The sigmaE and Cpx regulatory pathways: overlapping but distinct envelope stress responses. (1999) (190)
- Cpx signaling pathway monitors biogenesis and affects assembly and expression of P pili (2001) (188)
- Quality control in the bacterial periplasm. (2004) (187)
- Characterization of the two-protein complex in Escherichia coli responsible for lipopolysaccharide assembly at the outer membrane (2010) (184)
- The Bam machine: a molecular cooper. (2012) (180)
- Contact‐dependent growth inhibition requires the essential outer membrane protein BamA (YaeT) as the receptor and the inner membrane transport protein AcrB (2008) (178)
- A COMMUNITY OF ANTS , FUNGI , AND BACTERIA : A Multilateral Approach to Studying Symbiosis (2005) (177)
- cis-acting ompF mutations that result in OmpR-dependent constitutive expression (1991) (174)
- Outer Membrane Biogenesis. (2017) (171)
- The extracytoplasmic adaptor protein CpxP is degraded with substrate by DegP. (2005) (163)
- Mutations That Alter the Kinase and Phosphatase Activities of the Two-Component Sensor EnvZ (1998) (159)
- EnvZ, a transmembrane environmental sensor of Escherichia coli K-12, is phosphorylated in vitro (1988) (157)
- Characterization of the role of the Escherichia coli periplasmic chaperone SurA using differential proteomics (2009) (153)
- Dominant constitutive mutations in malT, the positive regulator gene of the maltose regulon in Escherichia coli. (1978) (152)
- Function of conserved histidine-243 in phosphatase activity of EnvZ, the sensor for porin osmoregulation in Escherichia coli (1997) (152)
- A bacterial environmental sensor that functions as a protein kinase and stimulates transcriptional activation. (1989) (151)
- Heat-shock proteins DnaK and GroEL facilitate export of LacZ hybrid proteins in E. coli (1990) (151)
- Genomic and Biochemical Insights into the Specificity of ETS Transcription Factors (2017) (149)
- Sequence analysis of mutations that prevent export of λ receptor, an Escherichia coli outer membrane protein (1980) (145)
- Periplasmic Peptidyl Prolyl cis-trans Isomerases Are Not Essential for Viability, but SurA Is Required for Pilus Biogenesis in Escherichia coli (2005) (144)
- Genetic analysis of the major outer membrane proteins of Escherichia coli. (1981) (140)
- Use of gene fusions to study outer membrane protein localization in Escherichia coli. (1977) (139)
- One of three transmembrane stretches is sufficient for the functioning of the SecE protein, a membrane component of the E. coli secretion machinery. (1991) (139)
- Transcriptional regulation of Escherichia coli K-12 major outer membrane protein 1b (1979) (135)
- Genetic Basis for Activity Differences Between Vancomycin and Glycolipid Derivatives of Vancomycin (2001) (131)
- Crl stimulates RpoS activity during stationary phase (1998) (127)
- Escherichia coli Starvation Diets: Essential Nutrients Weigh in Distinctly (2005) (124)
- On the significance of the retention of ligand by protein. (1975) (123)
- The free and bound forms of Lpp occupy distinct subcellular locations in Escherichia coli (2011) (121)
- Genetic analysis of the switch that controls porin gene expression in Escherichia coli K-12. (1989) (121)
- Disruption of lipid homeostasis in the Gram-negative cell envelope activates a novel cell death pathway (2016) (120)
- Lipoprotein LptE is required for the assembly of LptD by the β-barrel assembly machine in the outer membrane of Escherichia coli (2011) (118)
- The essential tension: opposed reactions in bacterial two-component regulatory systems. (1993) (116)
- Suppressor mutations in rpoA suggest that OmpR controls transcription by direct interaction with the alpha subunit of RNA polymerase (1991) (116)
- Mutations affecting localization of an Escherichia coli outer membrane protein, the bacteriophage λ receptor* (1980) (115)
- Mapping an Interface of SecY (PrlA) and SecE (PrlG) by Using Synthetic Phenotypes and In Vivo Cross-Linking (1999) (115)
- A signal sequence is not sufficient to lead β-galactosidase out of the cytoplasm (1980) (115)
- Nonconsecutive disulfide bond formation in an essential integral outer membrane protein (2010) (113)
- Sirtuins Are Evolutionarily Conserved Viral Restriction Factors (2014) (112)
- Importance of secondary structure in the signal sequence for protein secretion. (1983) (111)
- Porin Regulon of Escherichia coli (1995) (111)
- Outer membrane lipoprotein biogenesis: Lol is not the end (2015) (111)
- Tethering of CpxP to the inner membrane prevents spheroplast induction of the Cpx envelope stress response (2000) (109)
- PrlA suppressor mutations cluster in regions corresponding to three distinct topological domains. (1993) (108)
- Transposable lambda placMu bacteriophages for creating lacZ operon fusions and kanamycin resistance insertions in Escherichia coli (1985) (107)
- PrlA (SecY) and PrlG (SecE) interact directly and function sequentially during protein translocation in E. coli (1990) (107)
- Envelope stress responses: balancing damage repair and toxicity (2019) (106)
- Labeling of proteins with beta-galactosidase by gene fusion. Identification of a cytoplasmic membrane component of the Escherichia coli maltose transport system. (1980) (105)
- Effects of Antibiotics and a Proto-Oncogene Homolog on Destruction of Protein Translocator SecY (2009) (104)
- Conformation-specific labeling of BamA and suppressor analysis suggest a cyclic mechanism for β-barrel assembly in Escherichia coli (2013) (104)
- Transmembrane domain of surface-exposed outer membrane lipoprotein RcsF is threaded through the lumen of β-barrel proteins (2014) (103)
- Thesec andprl genes ofEscherichia coli (1990) (103)
- A mechanism of protein localization: the signal hypothesis and bacteria (1980) (102)
- A previously unidentified gene in the spc operon of Escherichia coli K12 specifies a component of the protein export machinery (1982) (102)
- Phosphorylation-dependent conformational changes in OmpR, an osmoregulatory DNA-binding protein of Escherichia coli. (1995) (101)
- Microbial genetics: The art and design of genetic screens: Escherichia coli (2003) (101)
- Starvation for Different Nutrients in Escherichia coli Results in Differential Modulation of RpoS Levels and Stability (2005) (101)
- prlF and yhaV encode a new toxin-antitoxin system in Escherichia coli. (2007) (101)
- Accumulation of the Enterobacterial Common Antigen Lipid II Biosynthetic Intermediate StimulatesdegP Transcription in Escherichia coli (1998) (98)
- Complex spatial distribution and dynamics of an abundant Escherichia coli outer membrane protein, LamB (2004) (98)
- Kinetic Analysis of the Assembly of the Outer Membrane Protein LamB in Escherichia coli Mutants Each Lacking a Secretion or Targeting Factor in a Different Cellular Compartment (2006) (97)
- Envelope Stress Responses: An Interconnected Safety Net. (2017) (96)
- Mutational activation of the Cpx signal transduction pathway of Escherichia coli suppresses the toxicity conferred by certain envelope‐associated stresses (1995) (96)
- Lambda placMu: a transposable derivative of bacteriophage lambda for creating lacZ protein fusions in a single step (1984) (96)
- Identification of the malK gene product. A peripheral membrane component of the Escherichia coli maltose transport system. (1981) (96)
- PrlA4 prevents the rejection of signal sequence defective preproteins by stabilizing the SecA–SecY interaction during the initiation of translocation (1998) (93)
- A small-molecule inhibitor of BamA impervious to efflux and the outer membrane permeability barrier (2019) (93)
- EnvZ functions through OmpR to control porin gene expression in Escherichia coli K-12 (1988) (92)
- D-ribose metabolism in Escherichia coli K-12: genetics, regulation, and transport (1984) (90)
- The Cpx Stress Response Confers Resistance to Some, but Not All, Bactericidal Antibiotics (2013) (89)
- Conversion of beta-galactosidase to a membrane-bound state by gene fusion. (1976) (88)
- Kinetic analysis of lamB mutants suggests the signal sequence plays multiple roles in protein export. (1986) (87)
- Making a beta-barrel: assembly of outer membrane proteins in Gram-negative bacteria. (2012) (85)
- Activation of the Escherichia coli β-barrel assembly machine (Bam) is required for essential components to interact properly with substrate (2012) (82)
- Redefining the essential trafficking pathway for outer membrane lipoproteins (2017) (82)
- Mutations altering the cellular localization of the phage lambda receptor, an Escherichia coli outer membrane protein. (1978) (81)
- PrlA and PrlG suppressors reduce the requirement for signal sequence recognition (1994) (81)
- A lipoprotein/β-barrel complex monitors lipopolysaccharide integrity transducing information across the outer membrane (2016) (80)
- Probing the barrier function of the outer membrane with chemical conditionality. (2006) (80)
- Isolation and characterization of chain-terminating nonsense mutations in a porin regulator gene, envZ (1983) (80)
- A genetic approach for analyzing the pathway of LamB assembly into the outer membrane of Escherichia coli. (1991) (78)
- Open reading frame expression vectors: a general method for antigen production in Escherichia coli using protein fusions to beta-galactosidase. (1983) (78)
- The allele‐specific synthetic lethality of prlA‐prlG double mutants predicts interactive domains of SecY and SecE. (1995) (77)
- Mutations that affect separate functions of OmpR the phosphorylated regulator of porin transcription in Escherichia coli. (1993) (76)
- Beta-galactosidase is inactivated by intermolecular disulfide bonds and is toxic when secreted to the periplasm of Escherichia coli (1995) (75)
- Genetic fusions as experimental tools. (1991) (75)
- BamE Modulates the Escherichia coli Beta-Barrel Assembly Machine Component BamA (2011) (74)
- Constitutive Activation of the Escherichia coli Pho Regulon Upregulates rpoS Translation in an Hfq-Dependent Fashion (2003) (74)
- Characterization of a stalled complex on the β-barrel assembly machine (2016) (74)
- Secretion of LamB-LacZ by the Signal Recognition Particle Pathway of Escherichia coli (2003) (71)
- Alpha: the Cinderella subunit of RNA polymerase. (1992) (71)
- Sequence information within the lamB genes in required for proper routing of the bacteriophage lambda receptor protein to the outer membrane of Escherichia coli K-12. (1982) (71)
- New suppressors of signal-sequence mutations, prlG, are linked tightly to the secE gene of Escherichia coli. (1989) (70)
- A Suppressor of Cell Death Caused by the Loss of σE Downregulates Extracytoplasmic Stress Responses and Outer Membrane Vesicle Production in Escherichia coli (2006) (70)
- LptE binds to and alters the physical state of LPS to catalyze its assembly at the cell surface (2014) (68)
- Identification of base pairs important for OmpR‐DNA interaction (1995) (68)
- cis-acting sites required for osmoregulation of ompF expression in Escherichia coli K-12 (1986) (68)
- Dissecting the Escherichia coli periplasmic chaperone network using differential proteomics (2012) (67)
- The Escherichia coli Phospholipase PldA Regulates Outer Membrane Homeostasis via Lipid Signaling (2018) (67)
- Signal transduction in bacteria: kinases that control gene expression. (1990) (64)
- Engineering Escherichia coli to secrete heterologous gene products. (1990) (62)
- The primary pathway of protein export in E. coli (1991) (61)
- Suppression of signal sequence defects and azide resistance in Escherichia coli commonly result from the same mutations in secA (1995) (61)
- OmpR mutants specifically defective for transcriptional activation. (1994) (61)
- Information within the mature LamB protein necessary for localization to the outer membrane of E coli K12 (1983) (58)
- LrhA Regulates rpoS Translation in Response to the Rcs Phosphorelay System in Escherichia coli (2006) (58)
- Crl Facilitates RNA Polymerase Holoenzyme Formation (2006) (58)
- Decline in ribosomal fidelity contributes to the accumulation and stabilization of the master stress response regulator sigmaS upon carbon starvation. (2007) (57)
- The LysR Homolog LrhA Promotes RpoS Degradation by Modulating Activity of the Response Regulator SprE (1999) (57)
- Genetic Fusions of the lac Operon: A New Approach to the Study of Biological Processes (1980) (56)
- Suppressor analysis suggests a multistep, cyclic mechanism for protein secretion in Escherichia coli. (1992) (55)
- Identification of OmpR: a positive regulatory protein controlling expression of the major outer membrane matrix porin proteins of Escherichia coli K-12 (1981) (55)
- RpoS Proteolysis Is Regulated by a Mechanism That Does Not Require the SprE (RssB) Response Regulator Phosphorylation Site (2004) (54)
- Molecular components of the signal sequence that function in the initiation of protein export (1982) (53)
- Intragenic regions required for LamB export. (1984) (53)
- The Response Regulator SprE (RssB) Is Required for Maintaining Poly(A) Polymerase I-Degradosome Association during Stationary Phase (2010) (52)
- The CpxQ sRNA Negatively Regulates Skp To Prevent Mistargeting of β-Barrel Outer Membrane Proteins into the Cytoplasmic Membrane (2016) (51)
- Periplasmic protein related to the sn-glycerol-3-phosphate transport system of Escherichia coli (1976) (51)
- Sequence information required for protein translocation from the cytoplasm (1987) (49)
- RpoS proteolysis is controlled directly by ATP levels in Escherichia coli. (2012) (49)
- Isolation and characterization of delta ompB strains of Escherichia coli by a general method based on gene fusions (1985) (48)
- Continuous Control in Bacterial Regulatory Circuits (2004) (48)
- Role for Skp in LptD Assembly in Escherichia coli (2013) (47)
- Isolation and characterization of mutations altering expression of the major outer membrane porin proteins using the local anaesthetic procaine. (1983) (47)
- Signal sequence processing is required for the assembly of LamB trimers in the outer membrane of Escherichia coli (1993) (47)
- Escherichia coli xonA (sbcB) mutants enhance illegitimate recombination. (1991) (44)
- Making a membrane on the other side of the wall. (2017) (42)
- Isolation of mutations in the alpha operon of Escherichia coli that suppress the transcriptional defect conferred by a mutation in the porin regulatory gene envZ (1987) (41)
- P Pilus Assembly Motif Necessary for Activation of the CpxRA Pathway by PapE in Escherichia coli (2004) (41)
- PrlA is important for the translocation of exported proteins across the cytoplasmic membrane of Escherichia coli. (1989) (40)
- Characterization and in vivo cloning of prlC, a suppressor of signal sequence mutations in Escherichia coli K12. (1987) (40)
- Inhibitor of intramembrane protease RseP blocks the σE response causing lethal accumulation of unfolded outer membrane proteins (2018) (39)
- Dominant Negative lptE Mutation That Supports a Role for LptE as a Plug in the LptD Barrel (2013) (39)
- RpoS-Dependent Transcriptional Control ofsprE: Regulatory Feedback Loop (2001) (39)
- Cyclic Enterobacterial Common Antigen Maintains the Outer Membrane Permeability Barrier of Escherichia coli in a Manner Controlled by YhdP (2018) (39)
- YejM Modulates Activity of the YciM/FtsH Protease Complex To Prevent Lethal Accumulation of Lipopolysaccharide (2020) (38)
- Classifying β-Barrel Assembly Substrates by Manipulating Essential Bam Complex Members (2016) (38)
- The first 28 amino acids of mature LamB are required for rapid and efficient export from the cytoplasm. (1987) (38)
- Substrate binding to BamD triggers a conformational change in BamA to control membrane insertion (2018) (38)
- Predicting Functionally Informative Mutations in Escherichia coli BamA Using Evolutionary Covariance Analysis (2013) (37)
- Escherichia coli prlC encodes an endopeptidase and is homologous to the Salmonella typhimurium opdA gene (1992) (36)
- Death by Lethal Injection (1997) (36)
- A second transport system for sn-glycerol-3-phosphate in Escherichia coli (1978) (35)
- Sites within gene lacZ of Escherichia coli for formation of active hybrid beta-galactosidase molecules (1979) (34)
- Mutations affecting localization of an Escherichia coli outer membrane protein, the bacteriophage lambda receptor. (1980) (33)
- Accumulation of Phosphatidic Acid Increases Vancomycin Resistance in Escherichia coli (2014) (33)
- Distinctive Roles for Periplasmic Proteases in the Maintenance of Essential Outer Membrane Protein Assembly (2017) (32)
- Physical properties of the bacterial outer membrane (2021) (32)
- The Activity of Escherichia coli Chaperone SurA Is Regulated by Conformational Changes Involving a Parvulin Domain (2016) (32)
- Transcriptional occlusion caused by overlapping promoters (2014) (32)
- Assembly of Outer Membrane β-Barrel Proteins: the Bam Complex. (2011) (31)
- Enhanced export of beta-galactosidase fusion proteins in prlF mutants is Lon dependent (1992) (30)
- The Activity and Specificity of the Outer Membrane Protein Chaperone SurA Are Modulated by a Proline Isomerase Domain (2013) (30)
- Gene Fusions (2000) (30)
- Sequence analysis of mutations that prevent export of lambda receptor, an Escherichia coli outer membrane protein. (1980) (30)
- The genetics of protein secretion in E. coli. (1990) (29)
- An Open Letter to Elias Zerhouni (2005) (29)
- Novel RpoS-Dependent Mechanisms Strengthen the Envelope Permeability Barrier during Stationary Phase (2016) (28)
- Mutation prlF1 relieves the lethality associated with export of beta-galactosidase hybrid proteins in Escherichia coli (1984) (27)
- Maltose transport in Escherichia coli K12. A comparison of transport kinetics in wild-type and lambda-resistant mutants as measured by fluorescence quenching. (1976) (27)
- Mutations that define the promoter of ompF, a gene specifying a major outer membrane porin protein (1985) (27)
- Sirtuin Lipoamidase Activity Is Conserved in Bacteria as a Regulator of Metabolic Enzyme Complexes (2017) (27)
- The Synthetic Phenotype of ΔbamB ΔbamE Double Mutants Results from a Lethal Jamming of the Bam Complex by the Lipoprotein RcsF (2019) (27)
- PrlC, a suppressor of signal sequence mutations in Escherichia coli, can direct the insertion of the signal sequence into the membrane. (1989) (26)
- Border Control: Regulating LPS Biogenesis. (2020) (26)
- Two-Dimensional Polyacrylamide Gel Electrophoresis of Envelope Proteins of Escherichia coli (1975) (26)
- Systems biology: Metabolite turns master regulator (2013) (26)
- Multicopy suppression of cold-sensitive sec mutations in Escherichia coli (1995) (26)
- Two cellular components, PrlA and SecB, that recognize different sequence determinants are required for efficient protein export (1988) (25)
- Lipoic Acid Metabolism in Escherichia coli : Isolation of Null Mutants Defective in Lipoic Acid Biosynthesis , Molecular Cloning and Characterization of the E . coli lip Locus , and Identification of the Lipoylated Protein of the Glycine Cleavage System (2005) (25)
- A practical guide to the construction and use of lac fusions in Escherichia coli. (2000) (25)
- Absence of the Outer Membrane Phospholipase A Suppresses the Temperature-Sensitive Phenotype of Escherichia coli degPMutants and Induces the Cpx and ςE Extracytoplasmic Stress Responses (2001) (24)
- A progenitor of the outer membrane LamB trimer (1988) (24)
- Transposition of λplacMu is mediated by the A protein altered at its carboxy-terminal end (1988) (24)
- The Response Regulator SprE (RssB) Modulates Polyadenylation and mRNA Stability in Escherichia coli (2009) (23)
- ASM Journals Eliminate Impact Factor Information from Journal Websites (2016) (23)
- Involvement of a tryptophan residue in the binding site of Escherichia coli galactose-binding protein. (1974) (21)
- Conferral of transposable properties to a chromosomal gene in Escherichia coli. (1980) (21)
- Increased expression of the bifunctional protein PrlF suppresses overproduction lethality associated with exported beta-galactosidase hybrid proteins in Escherichia coli (1990) (20)
- Outer Membrane Protein Insertion by the β-barrel Assembly Machine. (2019) (20)
- Structure of the malB region in Escherichia coli K12 (1979) (19)
- Isolation and characterization of mutants of Escherichia coli K12 affected in protein localization. (1983) (19)
- His–Asp Phosphorelay: Two Components or More? (1996) (19)
- The Porin Regulon: A Paradigm for the Two-Component Regulatory Systems (1996) (18)
- Phase separation in the outer membrane of Escherichia coli (2021) (17)
- A mutant Escherichia coli that attaches peptidoglycan to lipopolysaccharide and displays cell wall on its surface (2014) (17)
- Folding LacZ in the Periplasm of Escherichia coli (2014) (17)
- Conformational Changes That Coordinate the Activity of BamA and BamD Allowing β-Barrel Assembly (2017) (17)
- A signal sequence is not sufficient to lead beta-galactosidase out of the cytoplasm. (1980) (16)
- The inner membrane protein YhdP modulates the rate of anterograde phospholipid flow in Escherichia coli (2020) (16)
- Isolation and characterization of mutants deleted for the sulA-ompA region of the Escherichia coli K-12 chromosome (1986) (16)
- Resolution of glpA and glpT loci into separate operons in Escherichia coli K-12 strains (1979) (15)
- The Role of the Escherichia Coli Galactose-Binding Protein in Galactose Transport and Chemotaxis (1974) (14)
- ASM Journals Eliminate Impact Factor Information from Journal Websites (2016) (14)
- Membrane-derived oligosaccharides affect porin osmoregulation only in media of low ionic strength (1992) (14)
- The gain-of-function allele bamAE470K bypasses the essential requirement for BamD in β-barrel outer membrane protein assembly (2020) (14)
- A Suppressor Mutation That Creates a Faster and More Robust σE Envelope Stress Response (2016) (13)
- ASM Journals Eliminate Impact Factor Information from Journal Websites (2016) (13)
- The genetics of protein secretion in Escherichia coli. (1981) (12)
- The ASM Journals Committee Values the Contributions of Black Microbiologists (2020) (12)
- Functions of the BamBCDE Lipoproteins Revealed by Bypass Mutations in BamA (2020) (12)
- The Power of bacterial genetics : a literature-based course (1992) (11)
- A Convenient Synthesis of (2R)-Glyceryl-β-d-galactopyranoside A SUBSTRATE FOR β-GALACTOSIDASE, THE LACTOSE REPRESSOR, THE GALACTOSE-BINDING PROTEIN, AND THE β-METHYLGALACTOSIDE TRANSPORT SYSTEM (1973) (11)
- BLAST 1995: International Conference on Bacterial Locomotion and Signal Transduction (1995) (11)
- The "hidden ligand" of the galactose-binding protein. (1975) (10)
- Genetic studies on mechanisms of protein localization in Escherichia coli K-12. (1980) (10)
- Selection for mutants altered in the expression or export of outer membrane porin OmpF (1985) (10)
- Signal Sequence Mutations as Tools for the Characterization of LamB Folding Intermediates (2002) (9)
- Genetic Analysis of Protein Translocation (2019) (9)
- SprE Levels Are Growth Phase Regulated in a ςS-Dependent Manner at the Level of Translation (2000) (8)
- Chimeric genetics with beta-galactosidase. (1983) (8)
- Folding-Based Suppression of Extracytoplasmic Toxicity Conferred by Processing-Defective LamB (1998) (8)
- Null Mutations in a Nudix Gene, ygdP, Implicate an Alarmone Response in a Novel Suppression of Hybrid Jamming (2003) (7)
- Classic Spotlight: Gram-Negative Bacteria Have Two Membranes (2015) (7)
- β-Barrel Membrane Protein Assembly by the (2011) (6)
- Fine-Tuning of σE Activation Suppresses Multiple Assembly-Defective Mutations in Escherichia coli (2019) (6)
- Synthesis of l-(p-iodobenzenesulfonyl)-3,5-di-n-propyl isocyanurate. (1972) (6)
- CHAPTER 2 – Germ Warfare: The Mechanisms of Virulence Factor Delivery (2001) (6)
- The genetics of protein targeting in Escherichia coli K12 (1989) (6)
- Selection Procedure for Mutants Defective in the β-Methylgalactoside Transport System of Escherichia coli Utilizing the Compound 2R-Glyceryl-β-d-Galactopyranoside (1974) (6)
- lacZ fusions to genes that specify exported proteins: A general technique (2004) (6)
- Gene fusions to the ptsM/pel locus of Escherichia coli (2004) (5)
- Synthesis and pharmacological activity of 1-(arylsulfonyl)-3,5-dialkyl-s-triazine-2,4,6-(1H,3H,5H)-triones. (1973) (5)
- Remembering Malcolm J. Casadaban (2010) (4)
- Protein secretion in bacteria: a chemotherapeutic target? (1992) (4)
- The sacrificial adaptor protein Skp functions to remove stalled substrates from the β-barrel assembly machine (2021) (4)
- How Escherichia coli Became the Flagship Bacterium of Molecular Biology (2022) (4)
- ASM Journals Eliminate Impact Factor Information from Journal Websites (2016) (4)
- Mechanisms of protein localization (1983) (4)
- Pushing the envelope: Lessons learned from stressing bacteria (2004) (4)
- Uses of lac fusions for the study of biological problems (1985) (4)
- The ASM Journals Committee Values the Contributions of Black Microbiologists (2020) (3)
- Aromatic nitro musk synthesis (1970) (3)
- Sex to the rescue (2008) (3)
- ASM Journals Eliminate Impact Factor Information from Journal Websites (2016) (3)
- Global Protein-Turnover Quantification in Escherichia coli Reveals Cytoplasmic Recycling under Nitrogen-Limitation (2022) (3)
- Sugar-Coating Bacteria with Lipopolysaccharides (2007) (3)
- Erratum: Genetic analysis of the switch that controls porin gene expression in Escherichia coli K-12 (J. Mol. Biol. (1989) 210, 281-292) (1990) (3)
- Editorial and Policy Changes for 2013 (2012) (2)
- Genetic approaches to study export of LamB to the outer membrane. (1982) (2)
- Erratum for May and Silhavy, “The Escherichia coli Phospholipase PldA Regulates Outer Membrane Homeostasis via Lipid Signaling” (2018) (2)
- Envelope stress responses: balancing damage repair and toxicity (2019) (2)
- Genetic Analysis of Protein Localization (1983) (2)
- The signal hypothesis in bacteria. (1982) (2)
- ASM Journals Eliminate Impact Factor Information from Journal Websites (2016) (1)
- 2014 Jack Kenney Award for Outstanding Service (2014) (1)
- A convenient synthesis of (2R)-glyceryl-beta-D-galactopyranoside. A substrate for beta-galactosidase, the lactose repressor, the galactose-binding protein, and the beta-methylgalactoside transport system. (1973) (1)
- The ASM Journals Committee Values the Contributions of Black Microbiologists (2020) (1)
- ASM Journals Eliminate Impact Factor Information from Journal Websites (2016) (1)
- Isolation of Mutations in the a Operon of Escherichia coli (2003) (1)
- Transposition of lambda placMu is mediated by the A protein altered at its carboxy-terminal end. (1988) (1)
- Eschenichia coli (1)
- 6 - The Identification of the YaeT Complex and Its Role in the Assembly of Bacterial Outer Membrane β‐Barrel Proteins (2007) (1)
- Two-dimensional polyacylamide gel electrophoresis of envelope proteins of Escherichia coli. (1975) (1)
- Editorial and Policy Changes for 2012 (2011) (1)
- ASM Journals Eliminate Impact Factor Information from Journal Websites (2016) (1)
- The ASM Journals Committee Values the Contributions of Black Microbiologists (2020) (1)
- GUEST COMMENTARY Gene Fusions (2000) (1)
- Signal Sequence Processing IsRequired fortheAssembly of LamBTrimers intheOuterMembraneofEschenichia coli (1993) (1)
- Time To Go (2020) (1)
- Classifying (cid:2) -Barrel Assembly Substrates by Manipulating Essential Bam Complex Members (2016) (1)
- The ASM Journals Committee Values the Contributions of Black Microbiologists (2020) (1)
- [The cerebral form of the hypersensitivity of the carotid sinus reflex]. (1967) (0)
- Abstracts of papers presented at the 2000 Meeting on Molecular Genetics of Bacteria & Phages, August 22-August 27, 2000 (2000) (0)
- Escherichia coli Chaperone Activity in the Periplasm of Genetic Evidence for Parallel Pathways of (2001) (0)
- The ASM Journals Committee Values the Contributions of Black Microbiologists (2020) (0)
- Physical properties of the bacterial outer membrane (2021) (0)
- NOTES Membrane-Derived Oligosaccharides Affect PorinOsmoregulation OnlyinMediaofLowIonic Strength (1992) (0)
- Structure of N-terminal domain of E. Coli YaeT (2007) (0)
- Acknowledgment of Ad Hoc Reviewers (1997) (0)
- Acknowledgment of Ad Hoc Reviewers (2020) (0)
- 2016 Jack Kenney Award for Outstanding Service (2016) (0)
- PrlA4 prevents the rejection of signal sequence defective preproteins by stabilizing theSecA–SecY interaction during the initiation of translocation (2013) (0)
- 2011 Jack Kenney Award for Outstanding Service (2012) (0)
- Editorial and Policy Changes for 2015 (2014) (0)
- The ASM Journals Committee Values the Contributions of Black Microbiologists (2020) (0)
- 2020 Jack Kenney Award for Outstanding Service (2020) (0)
- 2019 Jack Kenney Award for Outstanding Service (2019) (0)
- The ASM Journals Committee Values the Contributions of Black Microbiologists (2020) (0)
- Modulation of RpoS Levels and Stability Results in Differential Escherichia coli Starvation for Different Nutrients in (2004) (0)
- 2018 Jack Kenney Award for Outstanding Service (2018) (0)
- Previous Recipients of GSA Awards (2015) (0)
- Mechanism of outer membrane destabilization by global reduction of protein content (2023) (0)
- Table of Contents (1992) (0)
- 2013 Jack Kenney Award for Outstanding Service (2014) (0)
- J Bact is 100 (2015) (0)
- Author response: A lipoprotein/β-barrel complex monitors lipopolysaccharide integrity transducing information across the outer membrane (2016) (0)
- The ASM Journals Committee Values the Contributions of Black Microbiologists (2020) (0)
- Mechanisms of Cellular Protein Localization (1984) (0)
- A mechanism to couple transport and export (1985) (0)
- Olaf Schneewind, 1961–2019: Scientist, Mentor, Friend (2019) (0)
- Acknowledgement of Ad Hoc Reviewers (2004) (0)
- Intragenic regions required for LamB export ( outer membrane / signal sequence / sorting signal / 1-galactosidase / hybrid protein ) (0)
- Acknowledgment of Ad Hoc Reviewers (2015) (0)
- 2017 Jack Kenney Award for Outstanding Service (2017) (0)
- Acknowledgment of Ad Hoc Reviewers (2015) (0)
- coli Escherichia RpoS proteolysis is controlled directly by ATP levels in Material (2012) (0)
- Acknowledgment of Ad Hoc Reviewers (2003) (0)
- Trade-offs constrain adaptive pathways to T6 survival (2022) (0)
- The ASM Journals Committee Values the Contributions of Black Microbiologists (2020) (0)
- Classic Spotlight: a Very Pleiotropic Mutant (2016) (0)
- The ASM Journals Committee Values the Contributions of Black Microbiologists (2020) (0)
- The Journal of Bacteriology Is 100 (2015) (0)
- State of the Journal (2018) (0)
- Patents and literature (1983) (0)
- Reflections of a Beer Auxotroph (2011) (0)
- Robert A. Weisberg (1937–2011) (2011) (0)
- The ASM Journals Committee Values the Contributions of Black Microbiologists (2020) (0)
- Cracking outer membrane biogenesis. (2022) (0)
- Acknowledgment of Ad Hoc Reviewers (2011) (0)
- PrIA is important for the translocation of exported proteins across the cytoplasmic membrane of Escherichia coil ( IacZ / ( 3-galactosidase fusion proteins / overproduction lethality / signal sequence / protein secretion ) (0)
- Mutations altering the cellular localization of the phage X receptor , an Escherichia coli outer membrane protein ( signal sequence / hybrid proteins / precursors / protein synthesis ) (0)
- Current Issues in Scientific Publishing (2019) (0)
- Acknowledgment of Ad Hoc Reviewers (2018) (0)
- SYNTH. VON 1-(P-JODBENZOLSULFONYL)-3,5-DI-N-PROPYL-ISOCYANURAT (1973) (0)
- The ASM Journals Committee Values the Contributions of Black Microbiologists (2020) (0)
- SYNTHESIS AND PHARMACOLOGICAL ACTIVITY OF 1‐(ARYLSULFONYL)‐3,5‐DIALKYL‐S‐TRIAZINE‐2,4,6‐(1H,3H,5H)‐TRIONES (1973) (0)
- Acknowledgment of Ad Hoc Reviewers (2019) (0)
- Editorial Board Highlights (2013) (0)
- Previous Recipients of GSA Awards (2014) (0)
- State of the Journal (2017) (0)
- Cell regulation: continually redefining the rules. (1998) (0)
- Membrane Sensor Protein Responsible for Anaerobic Repression of Operons Involved in the Central Aerobic Pathways (0)
- The ASM Journals Committee Values the Contributions of Black Microbiologists (2020) (0)
- State of the Journal (2016) (0)
- Enhanced Export of,3-Galactosidase Fusion Proteins inprlFMutants IsLonDependent (1992) (0)
- The ASM Journals Committee Values the Contributions of Black Microbiologists (2020) (0)
- Metabolite turns master regulator The phenomenon of catabolite repression enables microorganisms to use their favourite carbon source first. New work reveals α-ketoacids as key effectors of this process, with their levels regulating gene expression. See Article p.301 (2013) (0)
- 2012 Jack Kenney Award for Outstanding Service (2013) (0)
- ASM Journals Eliminate Impact Factor Information from Journal Websites (2016) (0)
- Sites Within GenelacZofEscherichia coli forFormation of Active Hybrid f?-Galactosidase Molecules (1979) (0)
- Classic Spotlight: Selected Highlights from the First 100 Years of the Journal of Bacteriology (2017) (0)
- Classic Spotlight: the Birth of the Transcriptional Activator (2016) (0)
- [Scleroderma diffusum and pregnancy]. (1971) (0)
- 2015 Jack Kenney Award for Outstanding Service (2015) (0)
- Acknowledgment of Ad Hoc Reviewers (2012) (0)
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