Thomas Lengauer | Academic Influence

Thomas Lengauer's AcademicInfluence.com Rankings

Thomas Lengauer

Computer Science

#495

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#514

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Database

#448

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#470

Historical Rank

computer-science Degrees

Thomas Lengauer

Mathematics

#2725

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#4147

Historical Rank

Applied Mathematics

#104

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#118

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Measure Theory

#514

World Rank

#724

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mathematics Degrees

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Computer Science
Mathematics

Thomas Lengauer's Degrees

PhD Mathematics University of Passau

Why Is Thomas Lengauer Influential?

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According to Wikipedia, Thomas Lengauer is a German computer scientist and computational biologist. Education Lengauer studied Mathematics at the Free University of Berlin, earning his Diploma in 1975 and a Dr. rer. nat. in 1976. Lengauer later gained an MSc and a PhD in computer science, both from Stanford University. He received his habilitation degree in computer science at Saarland University in 1984.

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Thomas Lengauer's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

ROCR: visualizing classifier performance in R (2005) (2754)
A fast flexible docking method using an incremental construction algorithm. (1996) (2433)
A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1 (2007) (1868)
Improved scoring of functional groups from gene expression data by decorrelating GO graph structure (2006) (1749)
Computing topological parameters of biological networks (2008) (1448)
Combinatorial algorithms for integrated circuit layout (1990) (1158)
Permutation importance: a corrected feature importance measure (2010) (1065)
Evaluation of the FLEXX incremental construction algorithm for protein–ligand docking (1999) (835)
A fast algorithm for finding dominators in a flowgraph (1979) (722)
A new measure for functional similarity of gene products based on Gene Ontology (2006) (679)
Computational methods for biomolecular docking. (1996) (633)
BiQ Analyzer: visualization and quality control for DNA methylation data from bisulfite sequencing (2005) (596)
Comprehensive Analysis of DNA Methylation Data with RnBeads (2014) (546)
Genetic variation in DLG5 is associated with inflammatory bowel disease (2004) (499)
Engineering Support Vector Machine Kerneis That Recognize Translation Initialion Sites (2000) (477)
Recruitment and activation of a lipid kinase by hepatitis C virus NS5A is essential for integrity of the membranous replication compartment. (2011) (467)
FlexE: efficient molecular docking considering protein structure variations. (2001) (441)
Sarcoidosis is associated with a truncating splice site mutation in BTNL2 (2005) (441)
Genomic Distribution and Inter-Sample Variation of Non-CpG Methylation across Human Cell Types (2011) (381)
Co-clustering of biological networks and gene expression data (2002) (379)
The International Human Epigenome Consortium: A Blueprint for Scientific Collaboration and Discovery (2016) (360)
A DNA methylation fingerprint of 1628 human samples. (2011) (359)
Classification with correlated features: unreliability of feature ranking and solutions (2011) (340)
Bioinformatics prediction of HIV coreceptor usage (2007) (322)
BLUEPRINT to decode the epigenetic signature written in blood (2012) (320)
AltAnalyze and DomainGraph: analyzing and visualizing exon expression data (2010) (279)
Mutations in the NB-ARC Domain of I-2 That Impair ATP Hydrolysis Cause Autoactivation1[OA] (2006) (275)
Diversity and complexity of HIV-1 drug resistance: A bioinformatics approach to predicting phenotype from genotype (2002) (259)
Geno2pheno: estimating phenotypic drug resistance from HIV-1 genotypes (2003) (256)
Dissection of the Inflammatory Bowel Disease Transcriptome Using Genome-Wide cDNA Microarrays (2005) (236)
CpG Island Methylation in Human Lymphocytes Is Highly Correlated with DNA Sequence, Repeats, and Predicted DNA Structure (2006) (227)
The implications of alternative splicing in the ENCODE protein complement (2007) (227)
NOXclass: prediction of protein-protein interaction types (2006) (208)
Making sense of big data in health research: Towards an EU action plan (2016) (205)
CpG Island Mapping by Epigenome Prediction (2007) (205)
FLEXS: a method for fast flexible ligand superposition. (1998) (204)
From hype to reality: data science enabling personalized medicine (2018) (203)
Multi-task learning for HIV therapy screening (2008) (202)
Placement of medium-sized molecular fragments into active sites of proteins (1996) (200)
The particle concept: placing discrete water molecules during protein‐ligand docking predictions (1999) (186)
Computational epigenetics (2008) (186)
DNA Methylation Dynamics of Human Hematopoietic Stem Cell Differentiation (2016) (183)
Predicting HIV Coreceptor Usage on the Basis of Genetic and Clinical Covariates (2007) (181)
Multiple automatic base selection: Protein–ligand docking based on incremental construction without manual intervention (1997) (179)
Pathway analysis in metabolic databases via differetial metabolic display (DMD) (2000) (169)
RnBeads 2.0: comprehensive analysis of DNA methylation data (2019) (164)
Epigenomic Profiling of Human CD4+ T Cells Supports a Linear Differentiation Model and Highlights Molecular Regulators of Memory Development. (2016) (159)
Flexible docking under pharmacophore type constraints (2002) (152)
An integrative approach to gain insights into the cellular function of human ataxin-2. (2005) (149)
Calculating the Statistical Significance of Changes in Pathway Activity From Gene Expression Data (2004) (143)
Inter-individual variation of DNA methylation and its implications for large-scale epigenome mapping (2008) (143)
Managing drug resistance in cancer: lessons from HIV therapy (2012) (143)
Learning multiple evolutionary pathways from cross-sectional data (2004) (142)
Novel technologies for virtual screening. (2004) (137)
An Algorithm for Finding Maximal Common Subtopologies in a Set of Protein Structures (1996) (137)
Structural and functional analysis of ataxin-2 and ataxin-3. (2004) (135)
Improving disease gene prioritization using the semantic similarity of Gene Ontology terms (2010) (134)
Centralization: a new method for the normalization of gene expression data (2001) (130)
Recco: recombination analysis using cost optimization (2006) (127)
Analysis of Gene Expression Data with Pathway Scores (2000) (125)
BiQ Analyzer HT: locus-specific analysis of DNA methylation by high-throughput bisulfite sequencing (2011) (123)
Time-space trade-offs in a pebble game (1977) (121)
Computational methods for the design of effective therapies against drug resistant HIV strains (2005) (111)
The pebbling problem is complete in polynomial space (1979) (107)
Ataxin-2 and huntingtin interact with endophilin-A complexes to function in plastin-associated pathways. (2005) (106)
Diversity and functional plasticity of eukaryotic selenoproteins: identification and characterization of the SelJ family. (2005) (103)
Structural Descriptors of gp120 V3 Loop for the Prediction of HIV-1 Coreceptor Usage (2007) (103)
Survey on the PABC recognition motif PAM2. (2004) (98)
Estimating HIV evolutionary pathways and the genetic barrier to drug resistance. (2005) (94)
Exposure to the gut microbiota drives distinct methylome and transcriptome changes in intestinal epithelial cells during postnatal development (2018) (91)
Information Technologies in Biomedicine (2008) (91)
Deep Sequencing Reveals Mutagenic Effects of Ribavirin during Monotherapy of Hepatitis C Virus Genotype 1-Infected Patients (2013) (91)
Geno2pheno[HCV] – A Web-based Interpretation System to Support Hepatitis C Treatment Decisions in the Era of Direct-Acting Antiviral Agents (2016) (89)
Mtreemix: a software package for learning and using mixture models of mutagenetic trees (2005) (89)
Docking of hydrophobic ligands with interaction-based matching algorithms (1999) (89)
EpiExplorer: live exploration and global analysis of large epigenomic datasets (2012) (88)
Combining transcription factor binding affinities with open-chromatin data for accurate gene expression prediction (2016) (86)
Novel Sm‐like proteins with long C‐terminal tails and associated methyltransferases (2004) (84)
Microarrays: how many do you need? (2002) (81)
Ensemble Methods for Classification in Cheminformatics (2004) (81)
Involvement of Novel Human Immunodeficiency Virus Type 1 Reverse Transcriptase Mutations in the Regulation of Resistance to Nucleoside Inhibitors (2006) (81)
Molecular basis of telaprevir resistance due to V36 and T54 mutations in the NS3-4A protease of the hepatitis C virus (2008) (80)
Two-stage method for protein-ligand docking. (1999) (79)
Simple consensus procedures are effective and sufficient in secondary structure prediction. (2003) (77)
Computational analysis of human protein interaction networks (2007) (77)
Tenofovir Resistance and Resensitization (2003) (76)
Automatic Generation of Complementary Descriptors with Molecular Graph Networks (2005) (75)
Local protein structure prediction using discriminative models (2006) (75)
The HIN domain of IFI-200 proteins consists of two OB folds. (2005) (75)
The Correlation between the Complexities of the Nonhierarchical and Hierarchical Versions of Graph Problems (1987) (74)
A new CARD15 mutation in Blau syndrome (2005) (73)
Selecting anti-HIV therapies based on a variety of genomic and clinical factors (2008) (73)
Synthesis and evaluation of (pyridylmethylene)tetrahydronaphthalenes/-indanes and structurally modified derivatives: potent and selective inhibitors of aldosterone synthase. (2005) (71)
Comparative genome-wide DNA methylation analysis of colorectal tumor and matched normal tissues (2012) (71)
Epigenetic dynamics of monocyte-to-macrophage differentiation (2016) (70)
Characterization and Structural Analysis of Novel Mutations in Human Immunodeficiency Virus Type 1 Reverse Transcriptase Involved in the Regulation of Resistance to Nonnucleoside Inhibitors (2007) (70)
DynaPred: A structure and sequence based method for the prediction of MHC class I binding peptide sequences and conformations (2006) (69)
Decision tree-based formation of consensus protein secondary structure prediction (1999) (68)
Comparison of Classifier Fusion Methods for Predicting Response to Anti HIV-1 Therapy (2008) (65)
Identification of PatL1, a human homolog to yeast P body component Pat1. (2007) (65)
Estimating cancer survival and clinical outcome based on genetic tumor progression scores (2005) (64)
A simulated annealing approach to the nesting problem in the textile manufacturing industry (1995) (63)
Mutations in the MutSα interaction interface of MLH1 can abolish DNA mismatch repair (2006) (62)
Hierarchical planarity testing algorithms (1989) (61)
Upper and Lower Bounds on the Complexity of the Min-Cut Linear Arrangement Problem on Trees (1982) (61)
Predicting the response to combination antiretroviral therapy: retrospective validation of geno2pheno-THEO on a large clinical database. (2009) (60)
Improved Prediction of Response to Antiretroviral Combination Therapy using the Genetic Barrier to Drug Resistance (2006) (60)
EpiGRAPH: user-friendly software for statistical analysis and prediction of (epi)genomic data (2009) (60)
DeepBlue epigenomic data server: programmatic data retrieval and analysis of epigenome region sets (2016) (60)
Methods for optimizing antiviral combination therapies (2003) (59)
Efficient Solution of Connectivity Problems on Hierarchically Defined Graphs (1988) (59)
Synthesis and evaluation of imidazolylmethylenetetrahydronaphthalenes and imidazolylmethyleneindanes: potent inhibitors of aldosterone synthase. (2005) (58)
A comprehensive analysis of 195 DNA methylomes reveals shared and cell-specific features of partially methylated domains (2018) (58)
Innovations: Bioinformatics-assisted anti-HIV therapy (2006) (58)
Improved cyclodextrin-based receptors for camptothecin by inverse virtual screening. (2007) (58)
Structural localization of disease‐associated sequence variations in the NACHT and LRR domains of PYPAF1 and NOD2 (2003) (57)
Time-efficient flexible superposition of medium-sized molecules (1997) (57)
IRECS: A new algorithm for the selection of most probable ensembles of side‐chain conformations in protein models (2007) (56)
CASP2 experiences with docking flexible ligands using FLEXX (1997) (56)
Proceedings of the Seventh International Conference on Intelligent Systems for Molecular Biology (1998) (56)
Factor interaction analysis for chromosome 8 and DNA methylation alterations highlights innate immune response suppression and cytoskeletal changes in prostate cancer (2007) (56)
VLSI Theory (1991) (55)
Moment invariants as shape recognition technique for comparing protein binding sites (2007) (53)
Geno2pheno: Interpreting Genotypic HIV Drug Resistance Tests (2001) (53)
Patients with high-grade gliomas harboring deletions of chromosomes 9p and 10q benefit from temozolomide treatment. (2005) (53)
Algorithmic Aspects of One-Dimensional Layout Compaction (1987) (51)
Bioinformatics : from genomes to therapies (2007) (50)
Protein threading by recursive dynamic programming. (1999) (50)
Efficient Analysis of Graph Properties on Context-free Graph Languages (Extended Abstract) (1988) (49)
Predicting Response to Antiretroviral Treatment by Machine Learning: The EuResist Project (2012) (49)
Arby: automatic protein structure prediction using profile-profile alignment and confidence measures (2004) (49)
Time-Efficient Docking of Flexible Ligands into Active Sites of Proteins (1995) (49)
Prediction of response to antiretroviral therapy by human experts and by the EuResist data‐driven expert system (the EVE study) (2010) (48)
Functional Evaluation of Domain-Domain Interactions and Human Protein Interaction Networks (2007) (48)
A Fully Computational Model for Predicting Percutaneous Drug Absorption (2006) (46)
Predicting MHC class I epitopes in large datasets (2010) (46)
Amino Acid Variations in Hepatitis C Virus P7 and Sensitivity to Antiviral Combination Therapy with Amantadine in Chronic Hepatitis C (2005) (46)
Black-white pebbles and graph separation (1981) (45)
Application of oncogenetic trees mixtures as a biostatistical model of the clonal cytogenetic evolution of meningiomas (2007) (43)
The complexity of compacting hierarchically specified layouts of integrated circuits (1982) (42)
Improved prediction of HIV‐1 coreceptor usage with sequence information from the second hypervariable loop of gp120. (2010) (41)
Genotypic coreceptor analysis. (2007) (40)
A Discrete Algorithm for Crystal Structure Prediction of Organic Molecules (1997) (40)
ProML - the Protein Markup Language for specification of protein sequences, structures and families (2002) (39)
Characterization of Novel HIV Drug Resistance Mutations Using Clustering, Multidimensional Scaling and SVM-Based Feature Ranking (2005) (39)
The nesting problem in the leather manufacturing industry (1995) (38)
Efficient Algorithms for Finding Minimum Spanning Forests of Hierarchically Defined Graphs (1987) (38)
Learning Mixtures of Localized Rules by Maximizing the Area Under the ROC Curve (2004) (38)
Structural modeling of ataxin‐3 reveals distant homology to adaptins (2002) (37)
Structural and functional comparison of the non-structural protein 4B in flaviviridae. (2007) (37)
The efficient solution of integer programs for hierarchical global routing (1991) (36)
Processing of Hierarchically Defined Graphs and Graph Families (1992) (36)
Sensitive Detection of Viral Transcripts in Human Tumor Transcriptomes (2013) (35)
Alignment of Non-Covalent Interactions at Protein-Protein Interfaces (2008) (35)
Multiple-ligand-based virtual screening: methods and applications of the MTree approach. (2005) (34)
Docking and scoring with alternative side‐chain conformations (2009) (34)
The Space Complexity of Pebble Games on Trees (1980) (33)
A robust framework for hierarchical floorplanning with integrated global wiring (1990) (33)
RigFit: A new approach to superimposing ligand molecules (1998) (32)
Improving HIV coreceptor usage prediction in the clinic using hints from next-generation sequencing data (2012) (32)
Analysis of Physicochemical and Structural Properties Determining HIV-1 Coreceptor Usage (2013) (32)
Confirmation of human protein interaction data by human expression data (2005) (31)
Upper and lower bounds on time-space tradeoffs (1979) (31)
Bioinformatics ‐ From Genomes to Drugs (2001) (31)
The HILL system : a design environment for the hierarchical specification, compaction, and simulation of integrated circuit layouts (1983) (31)
Exploiting Hierarchy in VLSI Design (1986) (30)
Quantitative comparison of within-sample heterogeneity scores for DNA methylation data (2020) (30)
Pyranose Oxidase Identified as A Member of the GMC Oxidoreductase Family (2003) (30)
Stable coreceptor usage of HIV in patients with ongoing treatment failure on HAART. (2006) (30)
Prevalence and characteristics of hepatitis B and C virus infections in treatment-naïve HIV-infected patients (2011) (30)
geno2pheno[ngs-freq]: a genotypic interpretation system for identifying viral drug resistance using next-generation sequencing data (2018) (30)
Unstructured Path Problems and the Making of Semirings (Preliminary Version) (1991) (29)
Epidemiology of Transmitted Drug Resistance in Chronically HIV-Infected Patients in Germany: The RESINA Study 2001–2009 (2012) (29)
On the Applicability of Elastic Network Normal Modes in Small-Molecule Docking (2012) (29)
On the Solution of Inequality Systems Relevant to IC-Layout (1984) (28)
GOTax: investigating biological processes and biochemical activities along the taxonomic tree (2007) (28)
Confidence measures for protein fold recognition (2002) (28)
Clinical significance of in vitro replication-enhancing mutations of the hepatitis C virus (HCV) replicon in patients with chronic HCV infection. (2005) (28)
MethMarker: user-friendly design and optimization of gene-specific DNA methylation assays (2009) (27)
Decomposing protein networks into domain-domain interactions (2005) (26)
Genotypic tropism testing by massively parallel sequencing: qualitative and quantitative analysis (2011) (26)
Failure of Dolutegravir First-Line ART with Selection of Virus Carrying R263K and G118R. (2019) (26)
Fully Automated Flexible Docking of Ligands into Flexible Synthetic Receptors Using Forward and Inverse Docking Strategies (2006) (26)
Computing closely matching upper and lower bounds on textile nesting problems (1998) (26)
Modelling binding between CCR5 and CXCR4 receptors and their ligands suggests the surface electrostatic potential of the co-receptor to be a key player in the HIV-1 tropism (2013) (26)
Enthalpy-Entropy Compensation upon Molecular Conformational Changes. (2015) (25)
Full genome ultra‐deep pyrosequencing associates G‐to‐A hypermutation of the hepatitis B virus genome with the natural progression of hepatitis B (2013) (25)
Linear algorithms for optimizing the layout of dynamic CMOS cells (1988) (25)
Mutations in Gp41 are Correlated with Coreceptor Tropism but Do Not Improve Prediction Methods Substantially (2011) (25)
MicroRNA Transcription Start Site Prediction with Multi-objective Feature Selection (2012) (25)
Unique and assay specific features of NOMe-, ATAC- and DNase I-seq data (2019) (25)
Preserving Charge and Oxidation State of Au(III) Ions in an Agent-Functionalized Nanocrystal Model System (2011) (24)
Algorithms—ESA '93 (1993) (24)
Algorithmic research problems in molecular bioinformatics (1993) (24)
Genotyping hepatitis B virus dual infections using population-based sequence data. (2012) (24)
BiQ Analyzer HiMod: an interactive software tool for high-throughput locus-specific analysis of 5-methylcytosine and its oxidized derivatives (2014) (23)
Proceedings of the Fifth Annual International Conference on Computational Biology, RECOMB 2001, Montréal, Québec, Canada, April 22-25, 2001 (2001) (23)
Protein Structure Prediction Methods for Drug Design (2000) (23)
On the Complexity of VLSI Computations (1981) (23)
Data and text mining ROCR : visualizing classifier performance in R (2005) (22)
A simple iterative approach to parameter optimization (2000) (22)
Proviral DNA as a Target for HIV-1 Resistance Analysis (2015) (22)
Personalized HIV therapy to control drug resistance. (2014) (22)
Disease-associated variants in PYPAF1 and NOD2 result in similar alterations of conserved sequence (2003) (21)
Arevir: A Secure Platform for Designing Personalized Antiretroviral Therapies Against HIV (2006) (20)
Detection of Distant Structural Similarities in a Set of Proteins Using a Fast Graph-Based Method (1997) (20)
Expression pattern analysis of transcribed HERV sequences is complicated by ex vivo recombination (2007) (20)
Geno2pheno[454]: A Web Server for the Prediction of HIV-1 Coreceptor Usage from Next-Generation Sequencing Data (2012) (20)
Efficient Algorithms for the Constraint Generation for Integrated Circuit Layout Compaction (1983) (20)
A recursive algorithm for efficient combinatorial library docking (2000) (20)
Selective Pressures of HLA Genotypes and Antiviral Therapy on Human Immunodeficiency Virus Type 1 Sequence Mutation at a Population Level (2007) (19)
Dealing with sparse data in predicting outcomes of HIV combination therapies (2010) (19)
An integrative approach for predicting interactions of protein regions (2008) (19)
Efficient Algorithms for Path Problems with Gernal Cost Citeria (1991) (19)
DASMI: exchanging, annotating and assessing molecular interaction data (2009) (19)
Prediction of HIV-1 coreceptor usage (tropism) by sequence analysis using a genotypic approach. (2011) (18)
Peptidomimetic escape mechanisms arise via genetic diversity in the ligand-binding site of the hepatitis C virus NS3/4A serine protease. (2012) (18)
Improving the quality of protein structure models by selecting from alignment alternatives (2006) (18)
Efficient decision procedures for graph properties on context-free graph languages (1993) (18)
Fast and numerically stable parametric alignment of biosequences (1997) (18)
Positive selection of HIV host factors and the evolution of lentivirus genes (2010) (17)
Correlation of amino acid variations within nonstructural 4B protein with initial viral kinetics during interferon‐alpha‐based therapy in HCV‐1b‐infected patients (2007) (17)
Local Function Conservation in Sequence and Structure Space (2008) (17)
Operations Research and Statistics (1990) (17)
Using drug exposure for predicting drug resistance – A data-driven genotypic interpretation tool (2017) (17)
Modeling amorphousSi3B3N7: Structure and elastic properties (2004) (16)
Improving fold recognition of protein threading by experimental distance constraints (2001) (16)
Advantages of predicted phenotypes and statistical learning models in inferring virological response to antiretroviral therapy from HIV genotype (2008) (16)
Robust and accurate hierarchical floorplanning with integrated global wiring (1993) (16)
Learning from Past Treatments and Their Outcome Improves Prediction of In Vivo Response to Anti-HIV Therapy (2011) (16)
Placement, Assignment, and Floorplanning (1990) (16)
Metabolic screening of Saccharomyces cerevisiae single knockout strains reveals unexpected mobilization of metabolic potential (2006) (16)
Rtreemix: an R package for estimating evolutionary pathways and genetic progression scores (2008) (16)
Structural and functional analysis of a novel mutation of CYP21B in a heterozygote carrier of 21-hydroxylase deficiency (2005) (16)
V3 Loop Sequence Space Analysis Suggests Different Evolutionary Patterns of CCR5- and CXCR4-Tropic HIV (2009) (15)
Inferring Viral Tropism from Genotype with Massively Parallel Sequencing: Qualitative and Quantitative Analysis (2008) (15)
Automated clustering of ensembles of alternative models in protein structure databases. (2004) (15)
Association of HCV-related mixed cryoglobulinemia with specific mutational pattern of the HCV E2 protein and CD81 expression on peripheral B lymphocytes. (2004) (15)
POEM: Parameter Optimization Using Ensemble Methods: Application to Target Specific Scoring Functions (2005) (15)
HLA class I allele associations with HCV genetic variants in patients with chronic HCV genotypes 1a or 1b infection. (2010) (15)
An expanded model of HIV cell entry phenotype based on multi-parameter single-cell data (2012) (15)
Dimerization of the hepatitis C virus nonstructural protein 4B depends on the integrity of an aminoterminal basic leucine zipper (2010) (15)
Dynamics of NRTI resistance mutations during therapy interruption. (2009) (14)
Supplemental Information Recruitment and Activation of a Lipid Kinase by Hepatitis C Virus NS 5 A Is Essential for Integrity of the Membranous Replication Compartment (2010) (14)
Sequence and Structure Analysis of Distantly-Related Viruses Reveals Extensive Gene Transfer between Viruses and Hosts and among Viruses (2015) (14)
Reference-free deconvolution, visualization and interpretation of complex DNA methylation data using DecompPipeline, MeDeCom and FactorViz (2020) (14)
Model Selection for Mixtures of Mutagenetic Trees (2006) (14)
Prediction of crystal structures of organic molecules (1999) (14)
Web-based analysis of (Epi-) genome data using EpiGRAPH and Galaxy. (2010) (14)
HIV prevalence and route of transmission in Turkish immigrants living in North-Rhine Westphalia, Germany (2011) (14)
HIV-1 mutational pathways under multidrug therapy (2011) (14)
Coronavirus-Pandemie – Die Krise nachhaltig überwinden (2020) (14)
Association Between HIV-1 Coreceptor Usage and Resistance to Broadly Neutralizing Antibodies (2014) (13)
Recursive Dynamic Programming for Adaptive Sequence and Structure Alignment (1995) (13)
Linear Algorithms For Two CMOS Layout Problems (1986) (13)
Identification of mammalian orthologs associates PYPAF5 with distinct functional roles (2003) (13)
A genotypic method for determining HIV-2 coreceptor usage enables epidemiological studies and clinical decision support (2016) (13)
Visualizing the Performance of Scoring Classifiers [R package ROCR version 1.0-11] (2020) (13)
Stability analysis of mixtures of mutagenetic trees (2008) (12)
Strategiekonzept "Molekulare Bioinformatik" (2008) (12)
Erratum to: Making sense of big data in health research: towards an EU action plan (2016) (12)
Efficient automatic part nesting on irregular and inhomogeneous surfaces (1993) (12)
Flexible Docking of Ligands into Synthetic Receptors Using a Two-Sided Incremental Construction Algorithm (2006) (11)
ISCB’s initial reaction to New England Journal of Medicine editorial on data sharing (2016) (11)
A method for finding consensus breakpoints in the cancer genome from copy number data (2013) (11)
Upper and lower bounds on time-space tradeoffs in a pebble game (1979) (11)
The Helmholtz Network for Bioinformatics: an integrative web portal for bioinformatics resources (2004) (11)
Integer Program formulations of Global Routing and Placement Problems (1993) (11)
Relative Principal Components Analysis: Application to Analyzing Biomolecular Conformational Changes (2018) (10)
Computational Biology at the Beginning of the Post-genomic Era (2001) (10)
Efficient computation of root mean square deviations under rigid transformations (2014) (10)
HERO: Hierarchical EMC-constrained routing (1992) (10)
DNA Methylation Patterns Facilitate the Identification of MicroRNA Transcription Start Sites: A Brain-Specific Study (2013) (10)
APOBEC3G/F as one possible driving force for co-receptor switch of the human immunodeficiency virus-1 (2011) (10)
The Role of Conformational Changes in Molecular Recognition. (2016) (10)
ISCB’s Initial Reaction to The New England Journal of Medicine Editorial on Data Sharing (2016) (10)
Integrating expression data with domain interaction networks (2008) (10)
Parameters Influencing Baseline HIV-1 Genotypic Tropism Testing Related to Clinical Outcome in Patients on Maraviroc (2015) (10)
Soluble immune markers in the different phases of chronic hepatitis B virus infection (2019) (10)
Derivation of a scoring function for crystal structure prediction. (2001) (10)
Rhinovirus prevalence as indicator for efficacy of measures against SARS-CoV-2 (2021) (9)
Protein function from sequence and structure data. (2003) (9)
Performance of Genotypic Coreceptor Measurement Using Geno2pheno[coreceptor] in B- and non-B HIV Subtypes in a Large Cohort of Therapy-experienced Patients in Germany (2009) (9)
History-alignment models for bias-aware prediction of virological response to HIV combination therapy (2012) (9)
CpG island methylation in human lymphocytes is highly correlated with DNA sequence patterns, repeat frequencies and predicted DNA structure (2005) (9)
Geno2pheno is predictive of short-term virological response (2002) (9)
Computing Upper and Lower Bounds on Textile Nesting Problems (1996) (9)
Clinical relevance of the 2'-5'-oligoadenylate synthetase/RNase L system for treatment response in chronic hepatitis C. (2009) (9)
Automated Layout Generation and Wiring Area Estimation for 3D Electronic Modules (2001) (9)
Hierarchical Bayes Model for Predicting Effectiveness of HIV Combination Therapies (2012) (9)
Inferring Short-Range Linkage Information from Sequencing Chromatograms (2013) (9)
Bioinformatical Assistance of Selecting Anti-HIV Therapies: Where Do We Stand? (2012) (9)
Conformational analysis of alternative protein structures (2007) (9)
A general concept for consistent documentation of computational analyses (2015) (9)
Computational recognition of potassium channel sequences (2006) (9)
Risk Factors Associated with Older Age in Treatment-Naive HIV-Positive Patients (2012) (9)
Multiple molecular superpositioning as an effective tool for virtual database screening (2000) (8)
Predicting protein structure classes from function predictions (2004) (8)
Centralization: A biologically sensible method for the normalization of gene expression data (2001) (8)
Hierarchical Planary Testing Algorithms (1986) (8)
Robust methods for EMC-driven routing (1994) (8)
Crystal Structure Prediction based on Statistical Potentials (1998) (8)
Parallel 'Go with the winners' algorithms in the LogP model (1997) (8)
Software tool for automated processing of 13C labeling data from mass spectrometric spectra. (2003) (8)
Clinical use, efficacy, and durability of maraviroc for antiretroviral therapy in routine care: A European survey (2019) (8)
Geno2pheno[coreceptor]: a Tool for Predicting Coreceptor Usage from Genotype and for Monitoring Coreceptor-associated Sequence Alterations (2005) (7)
Four results on the complexity of VLSI computations (1983) (7)
geno 2 pheno [ ngs-freq ] : a genotypic interpretation system for identifying viral drug resistance using next-generation sequencing data (2018) (7)
Corrigendum: Sarcoidosis is associated with a truncating splice site mutation in the gene BTNL2 (2005) (7)
Protein-protein interactions: analysis and prediction (2009) (7)
DeepBlueR: large-scale epigenomic analysis in R (2017) (7)
Fifteen years of Env C2V3C3 evolution in six individuals infected clonally with human immunodeficiency virus type 1 (2007) (7)
Endogenous or exogenous spreading of HIV-1 in Nordrhein-Westfalen, Germany, investigated by phylodynamic analysis of the RESINA Study cohort (2012) (7)
An analysis of ternary simulation as a tool for race detection in digital MOS circuits (1986) (7)
The Binary Network Flow Problem is Logspace Complete for P (1990) (7)
Results of the first international HIV-1 coreceptor proficiency panel test. (2017) (6)
Geno 2 pheno [ 454 ] : A Web Server for the Prediction of HIV-1 Coreceptor Usage from Next-Generation Sequencing Data (2012) (6)
Synthesis of multi-level logic with one symbolic input (1991) (6)
Editorial: Selection of papers of the German Conference of Bioinformatics (GCB) 2005 (2006) (6)
Integrative analysis of single-cell expression data reveals distinct regulatory states in bidirectional promoters (2018) (6)
Combined similarity and QSPR virtual screening for guest molecules of β-cyclodextrin (2007) (6)
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Long-term results of peripheral nerve repair: A comparison of nerve anastomosis with ethyl-cyanoacrylate and epineural sutures (2010) (0)
BIOINFORMATICS Improving HIV coreceptor usage prediction in the clinic using hints from next-generation sequencing data (2012) (0)
616 EFFECT OF RIBAVIRIN ON THE FREQUENCY OF RNASE L CLEAVAGE SITES WITHIN THE HEPATITIS C VIRAL GENOME (2009) (0)
FlexR - Predicting the structure of host-guest complexes (2004) (0)
Special RECOMB 2002 Issue (2004) (0)
NS3-4A protease domain of PDB structure with co-crystallized ligand CPX (yellow) 32 and a second ligand, SCH 446211 (light blue), taken from the superimposed PDB structure 30 (2011) (0)
Improved HIV-1 Drug-exposure Reconstruction with Linear Support Vector Machines (2014) (0)
A probabilistic algorithm for matching protein structures - and its application to detecting functionally relevant patterns (2010) (0)
Dissecting DNA Methylation in Human Aging (2016) (0)

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