Thomas M. Mcintyre
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Philosophy Biology
Thomas M. Mcintyre's Degrees
- PhD Biochemistry Stanford University
- Doctorate Medicine Stanford University
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(Suggest an Edit or Addition)Thomas M. Mcintyre's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Gut Microbial Metabolite TMAO Enhances Platelet Hyperreactivity and Thrombosis Risk (2016) (1136)
- Anti-inflammatory HDL becomes pro-inflammatory during the acute phase response. Loss of protective effect of HDL against LDL oxidation in aortic wall cell cocultures. (1995) (803)
- Endothelial cell interactions with granulocytes: tethering and signaling molecules. (1992) (767)
- Molecular cloning of human prostaglandin endoperoxide synthase type II and demonstration of expression in response to cytokines. (1993) (740)
- Platelet-activating factor. (1990) (730)
- Activated platelets mediate inflammatory signaling by regulated interleukin 1β synthesis (2001) (697)
- Oxygen radicals induce human endothelial cells to express GMP-140 and bind neutrophils (1991) (633)
- Activated platelets signal chemokine synthesis by human monocytes. (1996) (632)
- Coexpression of GMP-140 and PAF by endothelium stimulated by histamine or thrombin: a juxtacrine system for adhesion and activation of neutrophils (1991) (626)
- Escaping the Nuclear Confines: Signal-Dependent Pre-mRNA Splicing in Anucleate Platelets (2005) (623)
- Identification of an intracellular receptor for lysophosphatidic acid (LPA): LPA is a transcellular PPARγ agonist (2002) (544)
- Platelet-activating factor and related lipid mediators. (2000) (484)
- Prostaglandin H synthase 2 is expressed abnormally in human colon cancer: evidence for a transcriptional effect. (1996) (481)
- Hydrogen peroxide stimulates the synthesis of platelet-activating factor by endothelium and induces endothelial cell-dependent neutrophil adhesion. (1988) (435)
- Effect of platelet activating factor-acetylhydrolase on the formation and action of minimally oxidized low density lipoprotein. (1995) (425)
- Intracellular unesterified arachidonic acid signals apoptosis. (2000) (419)
- Altered expression of the mRNA stability factor HuR promotes cyclooxygenase-2 expression in colon cancer cells. (2001) (408)
- Cultured endothelial cells synthesize both platelet-activating factor and prostacyclin in response to histamine, bradykinin, and adenosine triphosphate. (1985) (407)
- Human endothelial cells in culture produce platelet-activating factor (1-alkyl-2-acetyl-sn-glycero-3-phosphocholine) when stimulated with thrombin. (1984) (399)
- Endothelial cell-associated platelet-activating factor: a novel mechanism for signaling intercellular adhesion (1990) (394)
- Monocyte tethering by P-selectin regulates monocyte chemotactic protein-1 and tumor necrosis factor-alpha secretion. Signal integration and NF-kappa B translocation. (1995) (391)
- Human plasma platelet-activating factor acetylhydrolase. Association with lipoprotein particles and role in the degradation of platelet-activating factor. (1987) (376)
- Thrombin stimulates the adherence of neutrophils to human endothelial cells in vitro. (1985) (374)
- Hepatic Lipid Partitioning and Liver Damage in Nonalcoholic Fatty Liver Disease (2009) (359)
- The platelet-activating factor signaling system and its regulators in syndromes of inflammation and thrombosis (2002) (357)
- Inflammatory roles of P-selectin. (1993) (342)
- Oxidatively modified LDL contains phospholipids with platelet-activating factor-like activity and stimulates the growth of smooth muscle cells. (1995) (312)
- Peroxisome Proliferators Enhance Cyclooxygenase-2 Expression in Epithelial Cells* (1999) (309)
- Post-transcriptional Control of Cyclooxygenase-2 Gene Expression (2000) (299)
- Human plasma platelet-activating factor acetylhydrolase. Purification and properties. (1987) (298)
- Signal-dependent translation of a regulatory protein, Bcl-3, in activated human platelets. (1998) (294)
- Human plasma platelet-activating factor acetylhydrolase. Oxidatively fragmented phospholipids as substrates. (1991) (291)
- Platelet-activating factor acetylhydrolase deficiency. A missense mutation near the active site of an anti-inflammatory phospholipase. (1996) (275)
- Platelet-activating Factor Acetylhydrolases* (1997) (268)
- Leukotrienes C4 and D4 stimulate human endothelial cells to synthesize platelet-activating factor and bind neutrophils. (1986) (268)
- Oxidized Alkyl Phospholipids Are Specific, High Affinity Peroxisome Proliferator-activated Receptor γ Ligands and Agonists* (2001) (266)
- Protein kinase C regulates the nuclear localization of diacylglycerol kinase-ζ (1998) (250)
- The lysosomal‐mitochondrial axis in free fatty acid–induced hepatic lipotoxicity (2008) (249)
- Endothelial Cell Inflammatory Responses to Tumor Necrosis Factor α (1996) (249)
- Platelet-activating factor: a phospholipid autacoid with diverse actions. (1993) (246)
- Mass spectrometric profiling of oxidized lipid products in human nonalcoholic fatty liver disease and nonalcoholic steatohepatitis[S] (2010) (236)
- Platelet-Activating Factor, a Pleiotrophic Mediator of Physiological and Pathological Processes (2003) (228)
- The Leukocyte Integrins* (2000) (218)
- An oxidized derivative of phosphatidylcholine is a substrate for the platelet-activating factor acetylhydrolase from human plasma. (1989) (217)
- Plasma Platelet-activating Factor Acetylhydrolase Is a Secreted Phospholipase A2 with a Catalytic Triad (*) (1995) (217)
- Oxidatively fragmented phosphatidylcholines activate human neutrophils through the receptor for platelet-activating factor. (1991) (215)
- Human macrophages secret platelet-activating factor acetylhydrolase. (1990) (215)
- Lysophosphatidic Acid Induces Neointima Formation Through PPARγ Activation (2004) (214)
- Release of Free F2-isoprostanes from Esterified Phospholipids Is Catalyzed by Intracellular and Plasma Platelet-activating Factor Acetylhydrolases* (2006) (214)
- Leukocyte adhesion deficiency syndromes: adhesion and tethering defects involving beta 2 integrins and selectin ligands. (2002) (211)
- Lipopolysaccharide Signaling without a Nucleus: Kinase Cascades Stimulate Platelet Shedding of Proinflammatory IL-1β–Rich Microparticles (2011) (209)
- Retrograde inflammatory signaling from neutrophils to endothelial cells by soluble interleukin-6 receptor alpha. (1997) (205)
- Oncostatin M is a proinflammatory mediator. In vivo effects correlate with endothelial cell expression of inflammatory cytokines and adhesion molecules. (1997) (202)
- Molecular Cloning of a Novel Human Diacylglycerol Kinase Highly Selective for Arachidonate-containing Substrates (*) (1996) (195)
- Neutrophil adherence to human endothelium in vitro occurs by CDw18 (Mo1, MAC-1/LFA-1/GP 150,95) glycoprotein-dependent and -independent mechanisms. (1988) (193)
- Inflammatory Platelet-activating Factor-like Phospholipids in Oxidized Low Density Lipoproteins Are Fragmented Alkyl Phosphatidylcholines* (1999) (181)
- Platelet-activating Factor Acetylhydrolase, and Not Paraoxonase-1, Is the Oxidized Phospholipid Hydrolase of High Density Lipoprotein Particles* (2003) (174)
- Vitamin C blocks inflammatory platelet-activating factor mimetics created by cigarette smoking. (1997) (174)
- Activation of human neutrophil phospholipase D by three separable mechanisms (1990) (173)
- Molecular Cloning and Characterization of a Novel Human Diacylglycerol Kinase (*) (1996) (163)
- Cancer Stem Cell‐Specific Scavenger Receptor CD36 Drives Glioblastoma Progression (2014) (162)
- Cell-cell interactions: leukocyte-endothelial interactions. (2003) (160)
- Adhesion and signaling in vascular cell-cell interactions. (1996) (159)
- Molecular Basis of the Interaction between Plasma Platelet-activating Factor Acetylhydrolase and Low Density Lipoprotein* (1999) (159)
- Platelet‐activating factor: a mediator for clinicians (1995) (156)
- Biologically Active Oxidized Phospholipids* (1999) (156)
- The emerging roles of PAF acetylhydrolase This work was supported by National Institutes of Health Grants HL44513, HL35828, and HL087018. Published, JLR Papers in Press, October 6, 2008. (2009) (153)
- Low-Density Lipoprotein in Hypercholesterolemic Human Plasma Induces Vascular Endothelial Cell Apoptosis by Inhibiting Fibroblast Growth Factor 2 Transcription (2003) (151)
- Inflammatory agonists induce cyclooxygenase type 2 expression by human neutrophils. (1998) (150)
- Platelet-activating factor acetylhydrolase increases during macrophage differentiation. A novel mechanism that regulates accumulation of platelet-activating factor. (1989) (150)
- Neutrophil activating factor (NAF) induces polymorphonuclear leukocyte adherence to endothelial cells and to subendothelial matrix proteins. (1989) (146)
- Activation of polymorphonuclear leukocytes reduces their adhesion to P-selectin and causes redistribution of ligands for P-selectin on their surfaces. (1995) (143)
- An Antimicrobial Peptide Regulates Tumor-Associated Macrophage Trafficking via the Chemokine Receptor CCR2, a Model for Tumorigenesis (2010) (142)
- Lipopolysaccharide Is a Direct Agonist for Platelet RNA Splicing1 (2008) (142)
- Production of platelet-activating factor by stimulated human polymorphonuclear leukocytes. Correlation of synthesis with release, functional events, and leukotriene B4 metabolism. (1987) (138)
- Novel leukocyte agonists are released by endothelial cells exposed to peroxide. (1992) (135)
- mTOR-dependent synthesis of Bcl-3 controls the retraction of fibrin clots by activated human platelets. (2007) (132)
- Change in protein phenotype without a nucleus: translational control in platelets. (2004) (131)
- Retinoic acid-inducible gene-I is induced in endothelial cells by LPS and regulates expression of COX-2. (2002) (130)
- Shear stress activates cytosolic phospholipase A2 (cPLA2) and MAP kinase in human endothelial cells. (1996) (129)
- Borrelia burgdorferi outer membrane protein A induces nuclear translocation of nuclear factor-kappa B and inflammatory activation in human endothelial cells. (1996) (128)
- Integrin-dependent Control of Translation: Engagement of Integrin αIIbβ3 Regulates Synthesis of Proteins in Activated Human Platelets (1999) (128)
- Endotoxin Contamination of Ovalbumin Suppresses Murine Immunologic Responses and Development of Airway Hyper-reactivity* (2003) (126)
- The regulation of platelet-activating factor production in endothelial cells. The role of calcium and protein kinase C. (1989) (124)
- Dipyridamole Selectively Inhibits Inflammatory Gene Expression in Platelet–Monocyte Aggregates (2005) (120)
- Deficiency of platelet-activating factor acetylhydrolase is a severity factor for asthma. (1999) (119)
- Cloning, expression, and chromosomal localization of human long-chain fatty acid-CoA ligase 4 (FACL4). (1998) (117)
- Protein kinase C activity appears to be required for the synthesis of platelet-activating factor and leukotriene B4 by human neutrophils. (1987) (115)
- Expression of Plasma Platelet-activating Factor Acetylhydrolase Is Transcriptionally Regulated by Mediators of Inflammation* (1998) (114)
- Mutant IDH1 and thrombosis in gliomas (2016) (114)
- Oxidized LDL contains inflammatory PAF-like phospholipids. (2001) (113)
- Outside-In Signals Delivered by Matrix Metalloproteinase-1 Regulate Platelet Function (2002) (113)
- Endothelial activation in ARDS. (1999) (113)
- The necrotic venom of the brown recluse spider induces dysregulated endothelial cell-dependent neutrophil activation. Differential induction of GM-CSF, IL-8, and E-selectin expression. (1994) (112)
- Cyclooxygenase-2 Is Induced in Monocytes by Peroxisome Proliferator Activated Receptor γ and Oxidized Alkyl Phospholipids from Oxidized Low Density Lipoprotein* (2002) (111)
- Production of platelet-activating factor by human vascular endothelial cells: evidence for a requirement for specific agonists and modulation by prostacyclin. (1985) (108)
- Mammalian platelet-activating factor acetylhydrolases. (1996) (107)
- Bioactive phospholipid oxidation products. (2000) (107)
- The interorgan metabolism of glutathione. (1980) (106)
- Differential Regulation of Matrix Metalloproteinase-9 by Monocytes Adherent to Collagen and Platelets (2001) (105)
- Comparison of the hydrolytic and transfer activities of rat renal gamma-glutamyltranspeptidase. (1979) (105)
- Human endothelial cells synthesize ENA-78: relationship to IL-8 and to signaling of PMN adhesion. (1997) (104)
- Lipopolysaccharide Stimulates Platelets through an IL-1β Autocrine Loop (2013) (102)
- Lipoproteins alter the catalytic behavior of the platelet-activating factor acetylhydrolase in human plasma. (1989) (97)
- Alpha toxin from Clostridium perfringens induces proinflammatory changes in endothelial cells. (1997) (96)
- The platelet-activating factor acetylhydrolase from human plasma prevents oxidative modification of low-density lipoprotein. (1992) (95)
- The Role of Platelet Activation and Inflammation in Early Brain Injury Following Subarachnoid Hemorrhage (2017) (94)
- Ultraviolet B Radiation Generates Platelet-activating Factor-like Phospholipids underlying Cutaneous Damage* (2005) (94)
- Endotoxins Stimulate Neutrophil Adhesion Followed by Synthesis and Release of Platelet-activating Factor in Microparticles* (2003) (93)
- P-selectin regulates platelet-activating factor synthesis and phagocytosis by monocytes. (1995) (90)
- Platelet-activating factor acetylhydrolase from human plasma. (1990) (89)
- Liver cells secrete the plasma form of platelet-activating factor acetylhydrolase. (1991) (88)
- Mitochondrial ceramide increases in UV-irradiated HeLa cells and is mainly derived from hydrolysis of sphingomyelin (2004) (87)
- Fluid flow activates a regulator of translation, p70/p85 S6 kinase, in human endothelial cells. (2000) (82)
- Protein kinase C regulates the nuclear localization of diacylglycerol kinase-zeta. (1998) (82)
- Exosome poly‐ubiquitin inhibits platelet activation, downregulates CD36 and inhibits pro‐atherothombotic cellular functions (2014) (80)
- Juxtacrine intercellular signaling: another way to do it. (1993) (78)
- Perspectives series: Cell adhesion in vascular biology. Adhesion and signaling in vascular cell-cell interactions (1996) (76)
- Ferric chloride-induced murine carotid arterial injury: A model of redox pathology☆ (2013) (74)
- The Cloning and Characterization of a Novel Human Diacylglycerol Kinase, DGKι* (1998) (74)
- Expression of fatty acid‐CoA ligase 4 during development and in brain (2000) (74)
- Cytotoxic Phospholipid Oxidation Products (2007) (73)
- Sol Sherry Lecture in Thrombosis: Molecular Events in Acute Inflammation (2002) (72)
- Phospholipase Action of Platelet-activating Factor Acetylhydrolase, but Not Paraoxonase-1, on Long Fatty Acyl Chain Phospholipid Hydroperoxides* (2007) (71)
- Synthesis and release of platelet-activating factor by stimulated human mononuclear phagocytes. (1988) (70)
- Neutrophils alter the inflammatory milieu by signal-dependent translation of constitutive messenger RNAs. (2004) (70)
- Monocyte Chemoattractant Protein-1 and 5-Lipoxygenase Products Recruit Leukocytes in Response to Platelet-Activating Factor-Like Lipids in Oxidized Low-Density Lipoprotein1 (2002) (70)
- Thrombin Stimulates Neutrophil Adherence by an Endothelial Cell‐Dependent Mechanism: Characterization of the Response and Relationship to Platelet‐Activating Factor Synthesis a (1986) (70)
- Platelet Activation by Low Concentrations of Intact Oxidized LDL Particles Involves the PAF Receptor (2009) (68)
- The platelet-activating factor acetylhydrolase from human erythrocytes. Purification and properties. (1993) (67)
- A novel syndrome of variant leukocyte adhesion deficiency involving defects in adhesion mediated by beta1 and beta2 integrins. (2001) (66)
- Activation of vascular cells by PAF-like lipids in oxidized LDL. (2002) (65)
- Chronic ethanol ingestion induces oxidative kidney injury through taurine-inhibitable inflammation. (2014) (63)
- Human endothelial cells regulate polymorphonuclear leukocyte degranulation (1998) (62)
- Activated Polymorphonuclear Leukocytes Rapidly Synthesize Retinoic Acid Receptor-α (2004) (60)
- Renal catabolism of glutathione. Characterization of a particulate rat renal dipeptidase that catalyzes the hydrolysis of cysteinylglycine. (1982) (57)
- Endothelial cells for studies of platelet-activating factor and arachidonate metabolites. (1990) (56)
- Bioactive oxidatively truncated phospholipids in inflammation and apoptosis: formation, targets, and inactivation. (2012) (54)
- Lysophosphatidylcholine and lyso-PAF display PAF-like activity derived from contaminating phospholipids. (2001) (54)
- Alternative splicing of the human diacylglycerol kinase ζ gene in muscle (1997) (54)
- Lipid metabolism and signal transduction in endothelial cells. (1990) (54)
- The interaction of leukocytes with platelets in blood coagulation (1995) (54)
- Proteasome Proteolysis Supports Stimulated Platelet Function and Thrombosis (2014) (53)
- A novel role of complement in retinal degeneration. (2011) (52)
- Chronic Alcohol Exposure Increases Circulating Bioactive Oxidized Phospholipids* (2010) (52)
- Platelet-activating factor mediates procoagulant activity on the surface of endothelial cells by promoting leukocyte adhesion. (1995) (51)
- The Role of Platelet-Activating Factor in Endothelial Cells (1990) (51)
- Synthesis of difluoromethyl substituted lysophosphatidic acid analogues (2004) (50)
- Intracellular PAF catabolism by PAF acetylhydrolase counteracts continual PAF synthesiss⃞ Published, JLR Papers in Press, August 10, 2007. (2007) (45)
- Somatic cell cloning in polyester stacks. (1982) (45)
- Phospholipid remodeling in human neutrophils. Parallel activation of a deacylation/reacylation cycle and platelet-activating factor synthesis. (1989) (45)
- Synthesis of platelet-activating factor by endothelial cells. The role of G proteins. (1990) (44)
- Adhesion and signaling in vascular cell--cell interactions. (1996) (43)
- ADAMDEC1 maintains a growth factor signaling loop in cancer stem cells. (2019) (43)
- Lipid oxidation and cardiovascular disease: introduction to a review series. (2010) (43)
- Escherichia coli Braun Lipoprotein Induces a Lipopolysaccharide-Like Endotoxic Response from Primary Human Endothelial Cells1 (2001) (43)
- Myeloperoxidase formation of PAF receptor ligands induces PAF receptor-dependent kidney injury during ethanol consumption. (2015) (42)
- Suppression of Mitochondrial Function by Oxidatively Truncated Phospholipids Is Reversible, Aided by Bid, and Suppressed by Bcl-XL* (2009) (42)
- D-2-Hydroxyglutarate Is an Intercellular Mediator in IDH-Mutant Gliomas Inhibiting Complement and T Cells (2018) (42)
- Human TMEM30a Promotes Uptake of Antitumor and Bioactive Choline Phospholipids into Mammalian Cells (2011) (41)
- Temporal correlation of measurements of airway hyperresponsiveness in ovalbumin-sensitized mice. (2002) (41)
- Inhibition of radiation-induced up-regulation of leukocyte adhesion to endothelial cells with the platelet-activating factor inhibitor, BN52021. (1995) (41)
- OxNASH Score Correlates with Histologic Features and Severity of Nonalcoholic Fatty Liver Disease (2011) (41)
- Oxidatively fragmented phospholipids as inflammatory mediators: the dark side of polyunsaturated lipids. (1995) (41)
- CD11b/CD18 integrin and a beta-glucan receptor act in concert to induce the synthesis of platelet-activating factor by monocytes. (1994) (40)
- Oxidatively Truncated Phospholipids Are Required Agents of Tumor Necrosis Factor α (TNFα)-induced Apoptosis* (2012) (40)
- Proliferation-dependent changes in release of arachidonic acid from endothelial cells. (1994) (40)
- Mutants of Escherichia coli defective in membrane phospholipid synthesis. Effects of cessation and reinitiation of phospholipid synthesis on macromolecular synthesis and phospholipid turnover. (1977) (39)
- Synergism Between Platelet-Activating Factor-Like Phospholipids and Peroxisome Proliferator-Activated Receptor γ Agonists Generated During Low Density Lipoprotein Oxidation That Induces Lipid Body Formation in Leukocytes1 (2003) (38)
- Fluid flow regulates E-selectin protein levels in human endothelial cells by inhibiting translation. (2003) (38)
- Circulating Platelet-Activating Factor Is Primarily Cleared by Transport, Not Intravascular Hydrolysis by Lipoprotein-Associated Phospholipase A2/ PAF Acetylhydrolase (2011) (37)
- Molecular cloning and characterization of a novel human diacylglycerol kinase zeta. (1996) (37)
- Coengagement of ICAM-3 and Fc receptors induces chemokine secretion and spreading by myeloid leukocytes. (1998) (36)
- Mutants of Escherichia coli defective in membrane phospholipid synthesis. Effect of cessation of net phospholipid synthesis on cytoplasmic and outer membranes. (1975) (35)
- Uteroplacental insufficiency decreases p53 serine-15 phosphorylation in term IUGR rat lungs. (2007) (35)
- Intracellular Erythrocyte Platelet-activating Factor Acetylhydrolase I Inactivates Aspirin in Blood* (2011) (35)
- Relative amounts of 1-O-alkyl- and 1-acyl-2-acetyl-sn-glycero-3-phosphocholine in stimulated endothelial cells. (1992) (35)
- Platelet-activating factor acetylhydrolase is increased in lung lavage fluid from patients with acute respiratory distress syndrome (2003) (33)
- Aspirin Hydrolysis in Plasma Is a Variable Function of Butyrylcholinesterase and Platelet-activating Factor Acetylhydrolase 1b2 (PAFAH1b2)* (2013) (33)
- Thymidine Phosphorylase Participates in Platelet Signaling and Promotes Thrombosis (2014) (33)
- SARS-CoV-2 Receptors are Expressed on Human Platelets and the Effect of Aspirin on Clinical Outcomes in COVID-19 Patients (2020) (32)
- Leucocyte-endothelial cell interactions (1992) (32)
- Platelet-activating factor acetylhydrolase in human erythrocytes. (1991) (32)
- Ceramide Generation in Situ Alters Leukocyte Cytoskeletal Organization and β2-Integrin Function and Causes Complete Degranulation* (2002) (32)
- Insulin and glucose play a role in foam cell formation and function (2006) (31)
- A yeast PAF acetylhydrolase ortholog suppresses oxidative death. (2008) (31)
- Identification of platelet-activating factor as the inflammatory lipid mediator in CCl4-metabolizing rat liver. (2001) (31)
- Activation of the acetyl-coenzyme A:lysoplatelet-activating factor acetyltransferase regulates platelet-activating factor synthesis in human endothelial cells. (1992) (30)
- Brush border membrane hydrolysis of S-benzyl-cysteine-p-nitroanilide, and activity of aminopeptidase M. (1980) (30)
- Ether-linked lipids and their bioactive species (2008) (29)
- CD36 Enhances Vascular Smooth Muscle Cell Proliferation and Development of Neointimal Hyperplasia (2019) (29)
- Two of the usual suspects, platelet-activating factor and its receptor, implicated in acute lung injury. (1999) (28)
- Characterization of the platelet-activating factor acetylhydrolase from human plasma by heterologous expression in Xenopus laevis oocytes. (1994) (28)
- Hirudin-based peptides block the inflammatory effects of thrombin on endothelial cells. (1990) (27)
- Induction of cyclooxygenase‐2 by human monocytes exposed to group B streptococci (2000) (26)
- Production of platelet-activating factor by endothelial cells. (1987) (26)
- Deubiquitinases Modulate Platelet Proteome Ubiquitination, Aggregation, and Thrombosis (2015) (26)
- The soluble protease ADAMDEC1 released from activated platelets hydrolyzes platelet membrane pro-epidermal growth factor (EGF) to active high-molecular-weight EGF (2017) (25)
- The cloning and developmental regulation of murine diacylglycerol kinase ζ (1998) (25)
- Endothelial Cell Confluence Regulates Cyclooxygenase-2 and Prostaglandin E2 Production That Modulate Motility* (2004) (25)
- Production of platelet-activating factor, a biologically active lipid, by vascular endothelial cells. (1987) (24)
- Bacterial lipopolysaccharide induces endothelial cells to synthesize a degranulating factor for neutrophils (1998) (23)
- Growth-dependent changes in arachidonic acid release from endothelial cells are mediated by protein kinase C and changes in diacylglycerol. (1993) (23)
- Apolipoprotein A1 regulates coenzyme Q10 absorption, mitochondrial function, and infarct size in a mouse model of myocardial infarction. (2014) (23)
- Effect of aspirin on short-term outcomes in hospitalized patients with COVID-19 (2021) (23)
- Engagement of ICAM-3 activates polymorphonuclear leukocytes: aggregation without degranulation or beta 2 integrin recruitment. (1998) (22)
- Integrin αDβ2 Is Dynamically Expressed by Inflamed Macrophages and Alters the Natural History of Lethal Systemic Infections1 (2008) (20)
- The cloning and characterization of a novel human diacylglycerol kinase, DGKiota. (1998) (20)
- PAF-acetylhydrolase expressed during megakaryocyte differentiation inactivates PAF-like lipids. (2009) (20)
- Synthesis of migration-resistant hydroxyethoxy analogues of lysophosphatidic acid. (2003) (19)
- The Production of Platelet-Activating Factor by Cultured Human Endothelial Cells: Regulation and Function (1987) (19)
- Juxtacrine interactions of endothelial cells with leukocytes: tethering and signaling molecules. (1993) (19)
- Escherichia coli mutants defective in membrane phospholipid synthesis: binding and metabolism of 1-oleoylglycerol 3-phosphate by a plsB deep rough mutant (1978) (19)
- Inflammation as an early component of atherosclerosis and vascular damage--a role for P-selectin and platelet-activating factor. (1996) (19)
- Enhanced Sphingomyelinase Activity Contributes to the Apoptotic Capacity of Electronegative Low-Density Lipoprotein. (2016) (18)
- Modulation of inflammatory platelet-activating factor (PAF) receptor by the acyl analogue of PAF (2018) (18)
- Escherichia coli Braun Lipoprotein (BLP) exhibits endotoxemia – like pathology in Swiss albino mice (2016) (18)
- Regulation of platelet-activating factor (PAF) synthesis and PAF-mediated neutrophil adhesion to endothelial cells activated by thrombin. (1992) (18)
- Sonic hedgehog signaling in hepatocellular carcinoma: A pilot study (2016) (17)
- Molecular characterization of the constitutive expression of the plasma platelet-activating factor acetylhydrolase gene in macrophages. (2003) (17)
- Circulating biologically active oxidized phospholipids show on-going and increased oxidative stress in older male mice (2013) (16)
- Integrin alphaDbeta2 is dynamically expressed by inflamed macrophages and alters the natural history of lethal systemic infections. (2008) (16)
- PAF, ceramide and pulmonary edema: alveolar flooding and a flood of questions. (2004) (16)
- Epidermal Growth Factor (EGF) Autocrine Activation of Human Platelets Promotes EGF Receptor–Dependent Oral Squamous Cell Carcinoma Invasion, Migration, and Epithelial Mesenchymal Transition (2018) (16)
- Brief review: molecular mechanisms of neutrophil binding to endothelium involving platelet-activating factor and cytokines. (1990) (16)
- Endothelial cells reestablish functional integrity after reversible permeabilization. (1991) (13)
- Platelet-Activating Factor and PAF-Like Mimetics (1996) (13)
- Erratum: Identification of an intracellular receptor for lysophosphatidic acid (LPA): LPA is a transcellular PPARγ agonist (Proceedings of the National Academy of Sciences of the United States of America (January 7, 2003) 100:1 (131-136)) (2003) (12)
- Mechanisms of vascular injury in the pathogenesis of infectious disease (1992) (12)
- The plasma PAF acetylhydrolase prevents oxidative modification of low density lipoprotein (1994) (12)
- Inflammatory PAF Receptor Signaling Initiates Hedgehog Signaling and Kidney Fibrogenesis During Ethanol Consumption (2015) (12)
- Lipopolysaccharide Cross-Tolerance Delays Platelet-Activating Factor-Induced Sudden Death in Swiss Albino Mice: Involvement of Cyclooxygenase in Cross-Tolerance (2016) (11)
- Determination of phospholipase activity of PAF acetylhydrolase. (2013) (11)
- Survival benefits in colorectal adenocarcinoma with the use of metformin among a black diabetic inner city population. (2017) (11)
- Platelet‐activating factor: antagonists, terminators, molecular mimics, and microbial opportunism (1996) (11)
- Platelet-activating factor receptor affects food intake and body weight (2015) (10)
- Alternative splicing of the human diacylglycerol kinase zeta gene in muscle. (1997) (10)
- Protein kinase C regulates the synthesis of platelet-activating factor by human monocytes. (1991) (10)
- Platelet-activating factor acetylhydrolase activity in human tissues and blood cells (1991) (10)
- Oxidized phospholipids with PAF-like bioactivity (1994) (9)
- The regulation of synthesis of platelet-activating factor by endothelial cells. (1988) (8)
- Inflammation in the vascular wall as an early event in atherosclerosis (1997) (8)
- Events at the Vascular Wall (2001) (8)
- Platelet Signal-Dependent Protein Synthesis (2005) (8)
- Functional and structural features of plasma platelet-activating factor acetylhydrolase. (1996) (8)
- Translational control of JunB, an AP‐1 transcription factor, in activated human endothelial cells (2013) (7)
- Impairment of endothelium-dependent aorta relaxation by phospholipid components of oxidized low-density lipoprotein. (2006) (7)
- Cardiovascular effects of platelet-activating factor. (1991) (6)
- Characterization of human UMP-CMP kinase enzymatic activity and 5' untranslated region. (2001) (6)
- Acute phase protein, α - 1- acid glycoprotein (AGP-1), has differential effects on TLR-2 and TLR-4 mediated responses. (2019) (6)
- The fate of platelet-activating factor: PAF acetylhydrolases from plasma and tissues (1996) (5)
- An open multicenter study of the efficacy of MDL 72,974A, a monoamine oxidase type B (MAO-B) inhibitor, in Parkinson's disease. (1993) (5)
- Novel Neutrophil Agonists: Oxidatively-Fragmented Phosphatidylcholines (1991) (4)
- Molecular Cloning and Characterization of a Novel Human Diacylglycerol Kinase (cid:122) * (1996) (4)
- Prostaglandins and Related Compounds Lipid Messengers with Many Actions (1996) (4)
- Platelet-activating factor: New roles in cell-cell interactions (1994) (4)
- Human macrophages secrete platelet-activating factor acetylhydrolase. A mechanism for resolution of pulmonary inflammation. (1991) (3)
- THE EFFECT OF SODIUM BICARBONATE, CEMENT KILN DUST AND AMMONIUM PERCHLORATE ON THE GROWTH OF LAMBS (1981) (3)
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