Thomas N. Seyfried
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Researcher, neurogenetic and biochemist
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Thomas N. Seyfriedbiology Degrees
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Biochemistry
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Biology
Thomas N. Seyfried's Degrees
- Bachelors Biology Boston College
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Why Is Thomas N. Seyfried Influential?
(Suggest an Edit or Addition)According to Wikipedia, Thomas N. Seyfried is an American professor of biology, genetics, and biochemistry at Boston College. He received his PhD from the University of Illinois Urbana-Champaign in 1976. His postdoctoral fellowship studies were in the Department of Neurology at the Yale University School of Medicine where he served as an assistant professor in neurology. He did undergraduate work at the University of New England, formerly St. Francis College, and received a master's degree in genetics from Illinois State University, Normal.
Thomas N. Seyfried's Published Works
Published Works
- On the origin of cancer metastasis. (2013) (746)
- Cancer as a metabolic disease (2010) (618)
- Meal frequency and timing in health and disease (2014) (396)
- Cancer as a metabolic disease: implications for novel therapeutics (2013) (362)
- Stem cells act through multiple mechanisms to benefit mice with neurodegenerative metabolic disease (2007) (297)
- The calorically restricted ketogenic diet, an effective alternative therapy for malignant brain cancer (2007) (275)
- Itaconic acid is a mammalian metabolite induced during macrophage activation. (2011) (250)
- Stimulation-dependent release of adenosine triphosphate from hippocampal slices (1989) (247)
- Metabolic management of glioblastoma multiforme using standard therapy together with a restricted ketogenic diet: Case Report (2010) (237)
- Role of glucose and ketone bodies in the metabolic control of experimental brain cancer (2003) (230)
- Targeting energy metabolism in brain cancer: review and hypothesis (2005) (214)
- GD3 ganglioside is a glycolipid characteristic of immature neuroectodermal cells (1985) (191)
- Caloric Restriction Inhibits Seizure Susceptibility in Epileptic EL Mice by Reducing Blood Glucose (2001) (189)
- Genes for epilepsy mapped in the mouse. (1991) (184)
- Dietary restriction reduces angiogenesis and growth in an orthotopic mouse brain tumour model (2002) (166)
- Perspectives on the metabolic management of epilepsy through dietary reduction of glucose and elevation of ketone bodies (2003) (164)
- A Review of Mouse Mutants as Genetic Models of Epilepsy (1985) (161)
- Antiangiogenic and Proapoptotic Effects of Dietary Restriction on Experimental Mouse and Human Brain Tumors (2004) (158)
- Cancer as a mitochondrial metabolic disease (2015) (149)
- The Ketogenic Diet and Hyperbaric Oxygen Therapy Prolong Survival in Mice with Systemic Metastatic Cancer (2013) (146)
- Ketone supplementation decreases tumor cell viability and prolongs survival of mice with metastatic cancer (2014) (144)
- Metabolic therapy: a new paradigm for managing malignant brain cancer. (2015) (142)
- Metabolic management of brain cancer. (2011) (133)
- Pericyte deficiencies lead to aberrant tumor vascularizaton in the brain of the NG2 null mouse. (2010) (132)
- Lipidomic analysis and electron transport chain activities in C57BL/6J mouse brain mitochondria (2008) (127)
- CEREBRAL, CEREBELLAR, AND BRAIN STEM GANGLIOSIDES IN MICE SUSCEPTIBLE TO AUDIOGENIC SEIZURES (1978) (119)
- Glycolipid and ganglioside metabolism imbalances in Huntington's disease (2007) (116)
- Glucose-dependent de Novo Lipogenesis in B Lymphocytes (2014) (110)
- Management of multifactorial idiopathic epilepsy in EL mice with caloric restriction and the ketogenic diet: role of glucose and ketone bodies (2004) (108)
- The Ketogenic Diet Inhibits Epileptogenesis in EL Mice: A Genetic Model for Idiopathic Epilepsy (2000) (104)
- Cancer as a Metabolic Disease: On the Origin, Management, and Prevention of Cancer (2012) (103)
- Oxygenation Prevents Sudden Death in Seizure‐prone Mice (2004) (101)
- Differential effects of energy stress on AMPK phosphorylation and apoptosis in experimental brain tumor and normal brain (2008) (97)
- Out of Warburg effect: An effective cancer treatment targeting the tumor specific metabolism and dysregulated pH. (2017) (92)
- ATP-induced synaptic potentiation in hippocampal slices (1989) (90)
- Caloric restriction in C57BL/6J mice mimics therapeutic fasting in humans (2006) (89)
- Isolation and characterization of human liver hematoside. (1978) (88)
- Ganglioside distribution in murine neural tumors. (1992) (88)
- Differential Cellular Enrichment of Gangliosides in the Mouse Cerebellum: Analysis Using Neurological Mutants (1982) (87)
- Glutamine targeting inhibits systemic metastasis in the VM‐M3 murine tumor model (2010) (84)
- N‐butyldeoxygalactonojirimycin reduces neonatal brain ganglioside content in a mouse model of GM1 gangliosidosis (2004) (81)
- Drug/diet synergy for managing malignant astrocytoma in mice: 2-deoxy-D-glucose and the restricted ketogenic diet (2008) (78)
- Complete correction of enzymatic deficiency and neurochemistry in the GM1-gangliosidosis mouse brain by neonatal adeno-associated virus-mediated gene delivery. (2007) (78)
- Metastatic cancer cells with macrophage properties: Evidence from a new murine tumor model (2008) (77)
- AAV-Mediated Gene Delivery in Adult GM1-Gangliosidosis Mice Corrects Lysosomal Storage in CNS and Improves Survival (2010) (77)
- A single intravenous rAAV injection as late as P20 achieves efficacious and sustained CNS Gene therapy in Canavan mice. (2013) (76)
- Audiogenic seizures in mice. (1979) (76)
- Substrate reduction reduces gangliosides in postnatal cerebrum-brainstem and cerebellum in GM1 gangliosidosis mice Published, JLR Papers in Press, February 1, 2005. DOI 10.1194/jlr.M400411-JLR200 (2005) (76)
- Enhanced Aspartate Release from Hippocampal Slices of Epileptic (El) Mice (1991) (74)
- Mitochondrial Substrate-Level Phosphorylation as Energy Source for Glioblastoma: Review and Hypothesis (2018) (73)
- Cellular Localization of Gangliosides in the Developing Mouse Cerebellum: Analysis Using the Weaver Mutant (1983) (73)
- Akt-Dependent Proapoptotic Effects of Dietary Restriction on Late-Stage Management of a Phosphatase and Tensin Homologue/Tuberous Sclerosis Complex 2–Deficient Mouse Astrocytoma (2008) (72)
- Therapeutic response in feline sandhoff disease despite immunity to intracranial gene therapy. (2013) (72)
- Spontaneous polyspike discharges in an epileptic mutant mouse (tottering) (1979) (71)
- Gangliosides influence angiogenesis in an experimental mouse brain tumor. (1999) (70)
- Environmental Risk Factors for Multifactorial Epilepsy in EL Mice (1999) (67)
- Genetic analysis of audiogenic seizure susceptibility in C57BL/6J X DBA/2J recombinant inbred strains of mice. (1980) (66)
- Calorie restriction as an anti-invasive therapy for malignant brain cancer in the VM mouse (2010) (65)
- The glucose ketone index calculator: a simple tool to monitor therapeutic efficacy for metabolic management of brain cancer (2015) (64)
- Thyroid hormone influence on the susceptibility of mice to audiogenic seizures. (1979) (64)
- Is the restricted ketogenic diet a viable alternative to the standard of care for managing malignant brain cancer? (2012) (64)
- Hippocampal neurons and glia in epileptic EL mice (2002) (63)
- Up-regulation of NG2 proteoglycan and interferon-induced transmembrane proteins 1 and 3 in mouse astrocytoma: a membrane proteomics approach. (2008) (63)
- Sex-Related Abnormalities in Substantia Nigra Lipids in Parkinson’s Disease (2018) (61)
- Non-Toxic Metabolic Management of Metastatic Cancer in VM Mice: Novel Combination of Ketogenic Diet, Ketone Supplementation, and Hyperbaric Oxygen Therapy (2015) (61)
- Increased amount of extracellular ATP in stimulated hippocampal slices of seizure prone mice (1989) (60)
- Mapping of two genes that influence susceptibility to audiogenic seizures in crosses of C57BL/6J and DBA/2J mice (1990) (60)
- Widespread correction of central nervous system disease after intracranial gene therapy in a feline model of Sandhoff disease (2014) (60)
- Influence of a ketogenic diet, fish-oil, and calorie restriction on plasma metabolites and lipids in C57BL/6J mice (2014) (60)
- Dynamic simulation of cardiolipin remodeling: greasing the wheels for an interpretative approach to lipidomics[S] (2010) (59)
- Influence of Caloric Restriction on Constitutive Expression of NF-κB in an Experimental Mouse Astrocytoma (2011) (59)
- Management of Glioblastoma Multiforme in a Patient Treated With Ketogenic Metabolic Therapy and Modified Standard of Care: A 24-Month Follow-Up (2018) (57)
- Cellular Distribution of Gangliosides in the Developing Mouse Cerebellum: Analysis Using the Staggerer Mutant (1984) (57)
- Ganglioside GM3 suppresses the proangiogenic effects of vascular endothelial growth factor and ganglioside GD1a (2008) (57)
- Improvement in motor and exploratory behavior in Rett syndrome mice with restricted ketogenic and standard diets (2009) (57)
- Press-pulse: a novel therapeutic strategy for the metabolic management of cancer (2017) (56)
- A novel pre-clinical in vivo mouse model for malignant brain tumor growth and invasion (2010) (54)
- Hypothesis: are neoplastic macrophages/microglia present in glioblastoma multiforme? (2011) (54)
- Inherited convulsive disorders in mice. (1986) (54)
- Targeting energy metabolism in brain cancer with calorically restricted ketogenic diets (2008) (51)
- N-butyldeoxygalactonojirimycin reduces brain ganglioside and GM2 content in neonatal Sandhoff disease mice (2008) (50)
- Does the existing standard of care increase glioblastoma energy metabolism? (2010) (50)
- In vitro growth environment produces lipidomic and electron transport chain abnormalities in mitochondria from non-tumorigenic astrocytes and brain tumours (2009) (50)
- Immunocytochemical localization of GD3 ganglioside to astrocytes in murine cerebellar mutants (1986) (49)
- Efficacy of Metabolically Supported Chemotherapy Combined with Ketogenic Diet, Hyperthermia, and Hyperbaric Oxygen Therapy for Stage IV Triple-Negative Breast Cancer (2017) (48)
- Differentiating N-linked glycan structural isomers in metastatic and nonmetastatic tumor cells using sequential mass spectrometry. (2008) (48)
- Comparative Analysis of Brain Lipids in Mice, Cats, and Humans with Sandhoff Disease (2009) (48)
- AAV-Mediated Gene Delivery in a Feline Model of Sandhoff Disease Corrects Lysosomal Storage in the Central Nervous System (2015) (47)
- N -butyldeoxynojirimycin reduces growth and ganglioside content of experimental mouse brain tumours (2001) (47)
- Cerebellar gangliosides and phospholipids in mutant mice with ataxia and epilepsy: the Tottering/Leaner syndrome (1981) (46)
- On the Origin of ATP Synthesis in Cancer (2020) (46)
- Perspectives on Brain Tumor Formation Involving Macrophages, Glia, and Neural Stem (2001) (45)
- Inheritance of Lysosomal Acid β-Galactosidase Activity and Gangliosides in Crosses of DBA/2J and Knockout Mice (2004) (45)
- Influence of caloric restriction on motor behavior, longevity, and brain lipid composition in Sandhoff disease mice (2006) (44)
- Perspectives on the mesenchymal origin of metastatic cancer (2010) (44)
- Therapeutic benefit of combining calorie-restricted ketogenic diet and glutamine targeting in late-stage experimental glioblastoma (2019) (42)
- Ganglioside composition of an experimental mouse brain tumor. (1987) (41)
- Ganglioside GM3 Is Antiangiogenic in Malignant Brain Cancer (2010) (40)
- Bis(monoacylglycero)phosphate: a secondary storage lipid in the gangliosidoses (2015) (40)
- Filipin recognizes both GM1 and cholesterol in GM1 gangliosidosis mouse brain (2011) (39)
- Biochemical Correlates of Epilepsy in the El Mouse: Analysis of Glial Fibrillary Acidic Protein and Gangliosides (1992) (39)
- Genetic linkage between the AH locus and a major gene that inhibits susceptibility to audiogenic seizures in mice. (1981) (39)
- Ganglioside Composition of Normal and Mutant Mouse Embryos (1989) (38)
- Behavioral seizure correlates in animal models of epilepsy: A road map for assay selection, data interpretation, and the search for causal mechanisms (2006) (37)
- Cerebellar lipid differences between R6/1 transgenic mice and humans with Huntington’s disease (2010) (36)
- Effects of Ketogenic metabolic therapy on patients with breast cancer: A randomized controlled clinical trial. (2020) (36)
- Ceruloplasmin gene defect associated with epilepsy in EL mice (1994) (36)
- Environmental stimuli shape microglial plasticity in glioma (2017) (36)
- Genetic Association Between Ca2+‐ATPase Activity and Audiogenic Seizures in Mice (1984) (35)
- Ganglioside abnormalities associated with failed neural differentiation in a T-locus mutant mouse embryo. (1987) (34)
- Brain Mitochondrial Lipid Abnormalities in Mice Susceptible to Spontaneous Gliomas (2008) (32)
- Provocative Question: Should Ketogenic Metabolic Therapy Become the Standard of Care for Glioblastoma? (2019) (32)
- Inhibition of Glycosphingolipid Biosynthesis Does Not Impair Growth or Morphogenesis of the Postimplantation Mouse Embryo (1998) (32)
- Experimental models of multifactorial epilepsies: the EL mouse and mice susceptible to audiogenic seizures. (1999) (32)
- Tumor-infiltrating macrophages influence the glycosphingolipid composition of murine brain tumors. (1998) (32)
- Enhanced Aspartate Release Related to Epilepsy in (EL) Mice (1994) (32)
- Gene‐linked shift in ganglioside distribution influences growth and vascularity in a mouse astrocytoma (2006) (31)
- Intraventricular Sialidase Administration Enhances GM1 Ganglioside Expression and Is Partially Neuroprotective in a Mouse Model of Parkinson’s Disease (2015) (31)
- Kindling Susceptibility and Genetic Seizure Predisposition in Inbred Mice (1991) (29)
- Absence of pathogenic mitochondrial DNA mutations in mouse brain tumors (2005) (29)
- Calcium ATPase Activities in Synaptic Plasma Membranes of Seizure‐Prone Mice (1986) (29)
- Does a ketogenic diet have beneficial effects on quality of life, physical activity or biomarkers in patients with breast cancer: a randomized controlled clinical trial (2020) (29)
- Expression of Mouse Sialic Acid on Gangliosides of a Human Glioma Grown as a Xenograft in SCID Mice (1999) (28)
- Influence of Host Cell Infiltration on the Glycolipid Content of Mouse Brain Tumors (1996) (28)
- Neurochemical, morphological, and neurophysiological abnormalities in retinas of Sandhoff and GM1 gangliosidosis mice (2007) (27)
- Therapeutic benefit of combining calorie-restricted ketogenic diet and glutamine targeting in late-stage experimental glioblastoma (2019) (27)
- Consideration of Ketogenic Metabolic Therapy as a Complementary or Alternative Approach for Managing Breast Cancer (2020) (27)
- Cellular localization of gangliosides in the mouse cerebellum: analysis using neurological mutants. (1984) (27)
- The role of metabolic therapy in treating glioblastoma multiforme (2015) (27)
- Ultrastructural characterization of the Mitochondria-associated membranes abnormalities in human astrocytomas: Functional and therapeutics implications (2017) (26)
- Genomic Imprinting and Audiogenic Seizures in Mice (1997) (26)
- Genes differentially expressed in the kindled mouse brain. (2001) (26)
- Influence of methotrexate and cisplatin on tumor progression and survival in the VM mouse model of systemic metastatic cancer (2010) (25)
- Dietary Restriction Promotes Vessel Maturation in a Mouse Astrocytoma (2011) (25)
- Genetic and environmental interactions determine seizure susceptibility in epileptic EL mice (2006) (24)
- Biochemical Study of Heterosis for Brain Myelin Content in Mice (1983) (24)
- Environmental influences on epilepsy gene mapping in EL mice. (1998) (24)
- The EL mouse: A natural model of autism and epilepsy (2010) (24)
- Examination of the brain mitochondrial lipidome using shotgun lipidomics. (2009) (24)
- Retinal Gangliosides in RCS Mutant Rats (1982) (23)
- Genetic heterogeneity for the development of audiogenic seizures in mice (1983) (22)
- Restricted ketogenic diet enhances the therapeutic action of N‐butyldeoxynojirimycin towards brain GM2 accumulation in adult Sandhoff disease mice (2010) (21)
- Ganglioside composition and histology of a spontaneous metastatic brain tumour in the VM mouse (2001) (21)
- Heterosis for brain myelin content in mice (1980) (21)
- Genetic analysis of cerebellar lipids in mice susceptible to audiogenic seizures (1984) (21)
- Genetic variability for regional brain gangliosides in five strains of young mice (1979) (20)
- Influence of ganglioside GM3 and high density lipoprotein on the cohesion of mouse brain tumor cells. (1997) (20)
- Influence of growth environment on the ganglioside composition of an experimental mouse brain tumor (1994) (19)
- Influence of Audiogenic Seizures on Synaptic Facilitation in Mouse Hippocampal Slices Is Mediated by N‐Methyl‐d‐Aspartate Receptor (1993) (19)
- Ethylenedioxy-PIP2 Oxalate Reduces Ganglioside Storage in Juvenile Sandhoff Disease Mice (2013) (19)
- Anti-Angiogenic and Pro-Apoptotic Effects of Dietary Restriction in Experimental Brain Cancer: Role of Glucose and Ketone Bodies (2005) (19)
- Therapeutic Effects of Stem Cells and Substrate Reduction in Juvenile Sandhoff Mice (2012) (19)
- Ganglioside biosynthesis in mouse embryos: sialyltransferase IV and the asialo pathway. (1994) (19)
- Genetic Study of Cationic ATPase Activities and Audiogenic Seizure Susceptibility in Recombinant Inbred and Congenic Strains of Mice (1984) (17)
- Can the Mitochondrial Metabolic Theory Explain Better the Origin and Management of Cancer than Can the Somatic Mutation Theory? (2021) (17)
- Sexual Dysfunction and Sudden Death in Epileptic Male EL Mice: Inheritance and Prevention with the Ketogenic Diet (2003) (17)
- Phylogenetic conservation of ganglioside GD3 expression during early vertebrate ontogeny. (1994) (17)
- Mycoplasma infection and hypoxia initiate succinate accumulation and release in the VM-M3 cancer cells. (2018) (16)
- Personalized Nutrition in Disrupting Cancer — Proceedings From the 2017 American College of Nutrition Annual Meeting (2018) (16)
- Synaptic vesicle glutamate uptake in epileptic (EL) mice (1997) (16)
- A Mathematical Model for the Determination of Steady-State Cardiolipin Remodeling Mechanisms Using Lipidomic Data (2011) (16)
- Influence of Serum and Hypoxia on Incorporation of [14C]-d-Glucose or [14C]-l-Glutamine into Lipids and Lactate in Murine Glioblastoma Cells (2015) (15)
- Genetic analysis of nucleotide triphosphatase activity in the mouse brain. (1994) (15)
- Serum gangliosides in mice with metastatic and non-metastatic brain tumors. (1994) (15)
- Glucose reduces the anticonvulsant effects of the ketogenic diet in EL mice (2014) (15)
- Need for new review of article on ketogenic dietary regimes for cancer patients (2017) (14)
- Cerebellar ganglioside abnormalities in pcd mutant mice (1990) (14)
- Bis(monoacylglycero)phosphate as a Macrophage Enriched Phospholipid (2015) (14)
- Mitochondria: The Ultimate Tumor Suppressor (2012) (13)
- Chapter 5 – Lipids (2012) (13)
- Caloric restriction and epilepsy: historical perspectives, relationship to the ketogenic diet, and analysis in epileptic EL mice. (2004) (13)
- Genetic analysis of serum thyroxine content and audiogenic seizures in recombinant inbred and congenic strains of mice (1984) (13)
- Abstract 53: Krebs cycle substrate-level phosphorylation drives metastatic cancer cells (2010) (12)
- Effect of purkinje cell loss on cerebellar gangliosides in nervous mutant mice (1987) (12)
- Ganglioside biosynthetic gene expression in experimental mouse brain tumors. (1997) (12)
- Molecular basis for heterosis for myelin basic protein content in mice. (1986) (12)
- Caprylic (Octanoic) Acid as a Potential Fatty Acid Chemotherapeutic for Glioblastoma. (2020) (12)
- Brain Lipid Analysis in Mice with Rett Syndrome (2009) (12)
- Ketone Strong: Emerging evidence for a therapeutic role of ketone bodies in neurological and neurodegenerative diseases (2014) (12)
- Altered ganglioside composition in virally transformed rat embryo fibroblasts. (1992) (11)
- Nothing in Cancer Biology Makes Sense Except in the Light of Evolution (2012) (11)
- Chapter 65 – Experimental Models of Epilepsy (1999) (11)
- The influence of ImuVert, a biological response modifier, on the growth and ganglioside composition of murine neural tumors. (1993) (11)
- Metabolic therapy and bioenergetic analysis: The missing piece of the puzzle (2021) (11)
- Nontoxic Targeting of Energy Metabolism in Preclinical VM-M3 Experimental Glioblastoma (2018) (10)
- GM1-gangliosidosis in American black bears: clinical, pathological, biochemical and molecular genetic characterization. (2014) (10)
- Lipid Composition of Whole Brain and Cerebellum in Hurler Syndrome (MPS IH) Mice (2011) (9)
- Abstract 985: Mitochondrial glutamine fermentation enhances ATP synthesis in murine glioblastoma cells (2011) (9)
- Genetics of the EL mouse: a multifactorial epilepsy model (1999) (9)
- Ketogenic Metabolic Therapy, Without Chemo or Radiation, for the Long-Term Management of IDH1-Mutant Glioblastoma: An 80-Month Follow-Up Case Report (2021) (9)
- Peripheral nervous system manifestations in a Sandhoff disease mouse model: nerve conduction, myelin structure, lipid analysis (2007) (8)
- Ceruloplasmin gene defect associated with epilepsy in EL mice (1995) (8)
- Genes, Respiration, Viruses, and Cancer (2012) (8)
- Is Mitochondrial Glutamine Fermentation a Missing Link in the Metabolic Theory of Cancer (2012) (8)
- Inheritance of brain weight in two strains of mice (1977) (8)
- Metabolic Management of Cancer (2012) (8)
- Thyroid hormone can restore the audiogenic seizure susceptibility of hypothyroid DBA 2J mice (1981) (8)
- Gene expression in the epileptic (EL) mouse hippocampus (2020) (8)
- Ganglioside GM 3 suppresses the proangiogenic effects of vascular endothelial growth factor and ganglioside GD 1 a (2008) (8)
- Substrate Reduction Therapy Reduces Ganglioside Content in Postnatal Cerebrum- Brainstem and Cerebellum in a Mouse Model of Gm1 Gangliosidosis (8)
- Respiratory Dysfunction in Cancer Cells (2012) (8)
- Ganglioside GM1 elevation in DBA/2 mouse embryos. (1990) (8)
- Involvement of ATP as a Neurotransmitter in the Hippocampus a (1990) (7)
- Targeting Energy Metabolism in Brain Cancer with Restricted Diets (2010) (7)
- Myelin Abnormalities in the Optic and Sciatic Nerves in Mice With GM1-Gangliosidosis (2015) (7)
- Chemical mutagenesis of a GPCR ligand: Detoxifying “inflammo-attraction” to direct therapeutic stem cell migration (2020) (7)
- Ketogenic Diet in Advanced Cancer: A Pilot Feasibility and Safety Trial in the Veterans Affairs Cancer Patient Population (2013) (7)
- Effect of Golgi membrane phospholipid composition on the molecular species of GM3 gangliosides synthesized by rat liver sialyltransferase. (1994) (7)
- Influence of the cribriform degeneration (cri) mutation on audiogenic seizures in DBA/2J mice (1979) (7)
- Ganglioside composition of a mouse brain tumor grown in the severe combined immunodeficiency (SCID) mouse. (1998) (7)
- Quantification of metastatic load in a syngeneic murine model of metastasis. (2017) (6)
- Influence of N2 or O2 on two alkylating agents in Neurospora crassa. (1975) (6)
- Nonallelism for the audiogenic seizure prone (Asp1) and the aryl hydrocarbon receptor (Ahr) loci in mice. (1998) (5)
- Intravenous delivery of adeno-associated viral gene therapy in feline GM1 gangliosidosis. (2021) (5)
- KETOGENIC DIET | Dietary Management of Epilepsy: Role of Glucose and Ketone Bodies (2009) (5)
- Novel ketone body therapy for managing Alzheimer's disease (2017) (5)
- Respiratory Insufficiency, the Retrograde Response, and the Origin of Cancer (2012) (5)
- Ganglioside storage diseases: on the road to management. (2014) (5)
- The VM Mouse Model of Glioblastoma Multiforme (2012) (5)
- Influence of trichloracetic acid-phosphotungstic acid on the thin layer chromatographic mobility of gangliosides (1977) (4)
- Brain cationic ATPase activities in epileptic (El) mice (1988) (4)
- Five‐day water‐only fasting decreased metabolic‐syndrome risk factors and increased anti‐aging biomarkers without toxicity in a clinical trial of normal‐weight individuals (2021) (4)
- KetoCal®, a novel ketogenic diet therapy for brain cancer (2006) (4)
- Caloric Restriction and Epilepsy (2004) (4)
- Metabolic control of brain cancer: role of glucose and ketone bodies (2005) (4)
- Cancer Treatment Strategies (2012) (3)
- Light- and Melanin Nanoparticle-Induced Cytotoxicity in Metastatic Cancer Cells (2021) (3)
- Energetics of Normal Cells and Cancer Cells (2012) (3)
- Mitochondrial Respiratory Dysfunction and the Extrachromosomal Origin of Cancer (2012) (3)
- Metabolically Supported Chemotherapy for Managing End-Stage Breast Cancer: A Complete and Durable Response (2021) (3)
- The total and mitochondrial lipidome of Artemia franciscana encysted embryos. (2016) (3)
- Localization of a gene for hippocampal epilepsy to chromosome 9. (1990) (3)
- Confusion Surrounds the Origin of Cancer (2012) (3)
- Effect of HBO therapy on adipose-derived stem cells, fibroblasts and co-cultures: In vitro study of oxidative stress, angiogenic potential and production of pro-inflammatory growth factors in co-cultures1. (2020) (3)
- The Restricted Ketogenic Diet : An Alternative Treatment Strategy for Glioblastoma Multiforme a report (2011) (3)
- The Warburg Dispute (2012) (3)
- Autosomal Dominant Inheritance of Brain Cardiolipin Fatty Acid Abnormality in VM/DK Mice: Association with Hypoxic-Induced Cognitive Insensitivity (2013) (3)
- Neutral glycolipid abnormalities in at-complex mutant mouse embryo (1992) (3)
- Heterososis for Myelin Content in Mice: A New Model for Studying Myelination (1983) (3)
- 94 Mitochondrial lipid and electron transport chain abnormalities in mouse brain tumors (2007) (2)
- Absence of brain ganglioside abnormalities in shambling mutant mice (1976) (2)
- Ganglioside GD3 biosynthesis in normal and mutant mouse embryos (1991) (2)
- Glycosphingolipid Biosynthesis May Not Be Necessary for Vertebrate Brain Development a (1998) (2)
- Proline Oxidation Supports Mitochondrial ATP Production When Complex I Is Inhibited (2022) (2)
- Perturbation of the yeast mitochondrial lipidome and associated membrane proteins following heterologous expression of Artemia-ANT (2018) (2)
- Is Respiration Normal in Cancer Cells (2012) (2)
- Restricted Ketogenic Diet Therapy for Primary Lung Cancer With Metastasis to the Brain: A Case Report (2022) (2)
- Gene Expression Changes in Kindling (2005) (2)
- Neutral glycolipid abnormalities in at-complex mutant mouse embryo (1992) (2)
- 19. Cancer Prevention (2012) (1)
- "Substrate reduction reduces gangliosides in postnatal cerebrum-brainstem and cerebellum in GM1 gangliosidosis mice" (vol 46, pg 744, 2004) (2005) (1)
- Metabolic management of microenvironment acidity in glioblastoma (2022) (1)
- MORPHOLOGICAL CHARACTERIZATION OF A NEW TRANSPLANTABLE BRAIN TUMOR IN THE VM MOUSE (1993) (1)
- Genetic and Biochemical Analysis of Mouse Brain Gangliosides (1976) (1)
- The ketogenic diet and hyperbaric oxygen therapy work synergistically to slow tumor growth and increase survival time in mice with systemic metastatic cancer (2013) (1)
- A novel pre-clinical mouse model of systemic metastatic cancer (2008) (1)
- Abnormalities in Growth Control, Telomerase Activity, Apoptosis, and Angiogenesis Linked to Mitochondrial Dysfunction (2012) (1)
- Ganglioside GD3 biosynthesis in normal and mutant mouse embryos (2004) (1)
- The Glucose Ketone Index predicts overall survival and metastasis of mouse tumor cells to visceral organs and brain (2022) (1)
- Functional and Therapeutic Implications of Mitochondrial Network and Mitochondria-Associated Membranes: The Glioma’s Case (2019) (1)
- Abstract 5421: Targeting glucose and glutamine for the metabolic management of systemic metastatic cancer (2010) (1)
- Answer to the critical remarks to the article by Khodabakhshi and colleagues reporting results from a randomized study on ketogenic diet. (2022) (1)
- Neural stem cell therapy in lysosomal storage disorders (2007) (1)
- Influence of Dietary Intake on Plasma Metabolites and Lipids in C57BL/6J Mice (2013) (0)
- Given the continuing dispute over the role of genetic abnormalities and protracted mitochondrial respiratory dysfunction in carcinogenesis, what is the core underlying entity? (2018) (0)
- Combination ketogenic diet, ketone supplementation, and hyperbaric oxygen therapy inhibits metastatic spread, slows tumor growth, and increases survival time in mice with metastatic cancer (123.7) (2014) (0)
- This includes enzyme replacement therapy , bone marrow transplantation , gene therapy and stem cell therapy (2008) (0)
- Images of Cancer (2012) (0)
- Evaluating a Dichloroacetate and Metformin Combination in a Mouse Model of Metastatic Cancer (2015) (0)
- N-butyldeoxygalactonojirimycin reduces postnatal cerebellar ganglioside content in a mouse model of GM1 gangliosidosis (2004) (0)
- 409. Complete Correction of Enzymatic Deficiency and Lysosomal Storage throughout the Brain in a Mouse Model of GM1-gangliosidosis after Neonatal Intracerebroventricular Injection of an AAV1 Vector Encoding Lysosomal Acid Beta- galactosidase (2006) (0)
- KETOGENIC DIET THERAPY FOR EPILEPSY AND BRAIN CANCER (2006) (0)
- Abstract 1159: Ketosis and hyperbaric oxygen elicit potent anti-cancer effects in vitro and in vivo (2015) (0)
- 41 Analysis of non-synaptic and synaptic mouse brain mitochondrial lipids and electron transport enzyme activities (2007) (0)
- Ganglioside GM3: An anti-angiogenic molecule with therapeutic potential (2008) (0)
- Book Review:Mouse Brain Development Andre M. Goffinet, Pasko Rakic (2001) (0)
- Influence of serum and hypoxia on endogenously synthesized lipids and lactate from radiolabeled glucose or glutamine in murine glioblastoma cells (2015) (0)
- Therapeutic assessment of substrate deprivation using NB-DGJ in GM1 storage disease mice (2003) (0)
- 126. Comparative Analysis of brain lipids in Mice, Cats, and Humans with Sandhoff disease (2009) (0)
- Abstract 4113: Restricted ketogenic diet reduces growth and distant organ metastasis in the murine VM-M3 metastatic tumor model (2014) (0)
- Supplemental ketone metabolic therapy slows tumor growth and increases survival time in mice with metastatic cancer (2013) (0)
- Case report: Resolution of malignant canine mast cell tumor using ketogenic metabolic therapy alone (2023) (0)
- Mycoplasma Infection Enhances the Immunological Activation and the Warburg Effect of Metastatic Tumor Cells (2015) (0)
- 3. Cancer Models (2012) (0)
- Patient Implementation of Metabolic Therapies for Cancer Management (2012) (0)
- Suppresses the Pro-Angiogenic Effects of Vascular Endothelial Growth Factor and Ganglioside GD 1 a (2008) (0)
- The ketogenic diet, an effective alternative therapy for brain cancer (2007) (0)
- Perturbation of the yeast mitochondrial lipidome and associated membrane proteins following heterologous expression of Artemia-ANT (2018) (0)
- Abstract 1704: Linking mitochondrial epigenetics to tumorigenesis and the cancer theory of Warburg. (2013) (0)
- Substrate deprivation therapy reduces brain ganglioside content and GM1 in neonatal storage disease mice (2002) (0)
- ' s report Title : Growth of human gastric cancer cells in nude mice is delayed by a ketogenic diet supplemented with omega-3 fatty acids and medium-chain triglycerides Version : 3 Date : 15 February 2008 (0)
- Ketosis and hyperbaric oxygen metabolic therapy elicits potent anti‐cancer effects in vitro and in vivo (2015) (0)
- Author's response to reviews Title: Growth of human gastric cancer cells in nude mice is delayed by a ketogenic diet supplemented with omega-3 fatty acids and medium-chain triglycerides Authors: (2008) (0)
- In Memoriam, Dr. Robert K. Yu (2023) (0)
- Branched‐chain amino acid supplementation does not exacerbate disease progression or decrease survival time in a murine model of metastatic cancer (824.2) (2014) (0)
- LIPOPOLYSACCHARIDE-INDUCED ATP-CITRATE LYASE IN B Lymphocytes : A REQUIREMENT FOR Lipogenesis in de Novo Glucose-dependent Immunology (2014) (0)
- Viability of HepG2 and MCF-7 Cells is not Correlated with Mitochondrial Bioenergetics (2022) (0)
- ' s report Title : Growth of human gastric cancer cells in nude mice is delayed by a ketogenic diet supplemented with omega-3 fatty acids and medium-chain triglycerides Version : 2 Date : 16 November 2007 (0)
- Malignant Brain Cancer Management with Metabolic Therapy (2015) (0)
- The effects of diet on prostate cancer outcomes (2022) (0)
- Bis(monoacylglycero)phosphate: An unusual macrophage‐associated phospholipid (2015) (0)
- Metabolic Management of Glioblastoma (2018) (0)
- Provocative Question: Should Ketogenic Metabolic Therapy Become the Standard of Care for Glioblastoma? (2019) (0)
- Abstract 5429: Robust in vitro cancer metabolism in non-tumorigenic microglial cells. (2013) (0)
- Case Studies and Personal Experiences in Using the Ketogenic Diet for Cancer Management (2012) (0)
- Does a ketogenic diet have any adverse effect on quality of life, physical activity, or biochemical factors in patients with breast cancer? A randomized controlled trial. (2020) (0)
- Biography of Dr. Robert K. Yu (2011) (0)
- The Tumor Mitochondrial Lipidome and Respiratory Bioenergetic Insufficiency (2012) (0)
- Endogenous quinones sustain NADH oxidation by complex I during anoxia, supporting substrate-level phosphorylation in mouse liver mitochondria (2018) (0)
- Ethylenedioxy-PIP2 Oxalate Reduces Ganglioside Storage in Juvenile Sandhoff Disease Mice (2013) (0)
- Property based designed inhibitors of glycosphingolipid synthesis lower ganglioside GM2 in the Sandhoff mouse (2013) (0)
- Localization of epilepsy genes in mice (1992) (0)
- Residual Complex I activity supports glutamate catabolism and mtSLP via canonical Krebs cycle activity during acute anoxia without OXPHOS (2022) (0)
- Abstract 4318: Mycoplasma arginini infection shifts the energy catabolism ratio of metastatic macrophages towards fermentation and is associated with an increase in primary tumor size, metastasis and malignancy (2014) (0)
- Therapeutic Effects of Stem Cells and Substrate Reduction in Juvenile Sandhoff Mice (2012) (0)
- Chapter 17 – Convulsive Disorders (2007) (0)
- Workshop W2: New Insights on Inherited Neurological Storage Diseases (2004) (0)
- Abstract 1905: Influence of serum and oxygen on lipid biosynthesis and energy metabolism in murine glioblastoma. (2013) (0)
- Modeling Epileptic Disorders in Mice (1999) (0)
- Effects of substrate deprivation therapy on brain lipids in neonatal GML storage disease mice (2003) (0)
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