Thomas P. Davis
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Engineering Computer Science
Thomas P. Davis's Degrees
- PhD Computer Science Stanford University
- Masters Electrical Engineering University of California, Berkeley
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(Suggest an Edit or Addition)Thomas P. Davis's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- The Blood-Brain Barrier/Neurovascular Unit in Health and Disease (2005) (2339)
- Molecular physiology and pathophysiology of tight junctions in the blood–brain barrier (2001) (769)
- Cerebral microvascular changes in permeability and tight junctions induced by hypoxia-reoxygenation. (2002) (363)
- Vascular dysfunction—The disregarded partner of Alzheimer's disease (2019) (361)
- Calcium Modulation of Adherens and Tight Junction Function: A Potential Mechanism for Blood-Brain Barrier Disruption After Stroke (2002) (282)
- Oxidative Stress Increases Blood–Brain Barrier Permeability and Induces Alterations in Occludin during Hypoxia–Reoxygenation (2010) (261)
- Inflammatory pain alters blood-brain barrier permeability and tight junctional protein expression. (2001) (254)
- Glycopeptide enkephalin analogues produce analgesia in mice: evidence for penetration of the blood-brain barrier. (1994) (220)
- Impact of Strain Type on Detection of Toxigenic Clostridium difficile: Comparison of Molecular Diagnostic and Enzyme Immunoassay Approaches (2010) (219)
- Nicotine increases in vivo blood–brain barrier permeability and alters cerebral microvascular tight junction protein distribution (2004) (199)
- Peptide drug modifications to enhance bioavailability and blood-brain barrier permeability (2001) (194)
- Effects of hypoxia-reoxygenation on rat blood-brain barrier permeability and tight junctional protein expression. (2003) (187)
- Transporters at CNS barrier sites: obstacles or opportunities for drug delivery? (2014) (179)
- A model for hypokinesia: effects on muscle atrophy in the rat. (1980) (158)
- Nicotine and cotinine modulate cerebral microvascular permeability and protein expression of ZO-1 through nicotinic acetylcholine receptors expressed on brain endothelial cells. (2002) (154)
- Bioavailability and Transport of Peptides and Peptide Drugs into the Brain (1997) (151)
- Rapid Detection of Staphylococcus aureus and Methicillin-Resistant S. aureus (MRSA) in Wound Specimens and Blood Cultures: Multicenter Preclinical Evaluation of the Cepheid Xpert MRSA/SA Skin and Soft Tissue and Blood Culture Assays (2009) (148)
- Chronic inflammatory pain leads to increased blood-brain barrier permeability and tight junction protein alterations. (2005) (146)
- Combination of hypoxia/aglycemia compromises in vitro blood-brain barrier integrity. (1999) (138)
- Blood-brain barrier integrity and glial support: mechanisms that can be targeted for novel therapeutic approaches in stroke. (2012) (136)
- Doxepin effects on chronic pain, depression and plasma opioids. (1982) (133)
- Transforming Growth Factor-β Signaling Alters Substrate Permeability and Tight Junction Protein Expression at the Blood-Brain Barrier during Inflammatory Pain (2009) (130)
- Antinociceptive profile of biphalin, a dimeric enkephalin analog. (1993) (127)
- High-performance liquid-chromatographic separation and fluorescence measurement of biogenic amines in plasma, urine, and tissue. (1978) (119)
- Regulation of blood–brain barrier integrity by microglia in health and disease: A therapeutic opportunity (2020) (118)
- Regional distribution of putative vasopressin receptors in rat brain and pituitary by quantitative autoradiography. (1984) (117)
- Development of neuropeptide drugs that cross the blood-brain barrier (2011) (116)
- Enkephalin glycopeptide analogues produce analgesia with reduced dependence liability. (2000) (115)
- Structure, Function, and Regulation of the Blood-Brain Barrier Tight Junction in Central Nervous System Disorders (2020) (113)
- Protein Kinase C Activation Modulates Reversible Increase in Cortical Blood–Brain Barrier Permeability and Tight Junction Protein Expression during Hypoxia and Posthypoxic Reoxygenation (2010) (108)
- Improved bioavailability to the brain of glycosylated Met-enkephalin analogs (2000) (105)
- Hypoxia/aglycemia alters expression of occludin and actin in brain endothelial cells. (2005) (105)
- Aldosterone and ADH response to heat and dehydration in cattle. (1980) (102)
- Blood-brain barrier tight junctions are altered during a 72-h exposure to lambda-carrageenan-induced inflammatory pain. (2002) (98)
- Protection against hypoxia-induced increase in blood-brain barrier permeability: role of tight junction proteins and NFκB (2003) (98)
- Protein expression of brain endothelial cell E-cadherin after hypoxia/aglycemia: influence of astrocyte contact (1999) (98)
- Distribution and analgesia of [3H][D-Pen2, D-Pen5]enkephalin and two halogenated analogs after intravenous administration. (1991) (98)
- Smoking and ischemic stroke: a role for nicotine? (2002) (97)
- Peripheral inflammatory hyperalgesia modulates morphine delivery to the brain: a role for P‐glycoprotein (2007) (93)
- Improved blood-brain barrier penetration and enhanced analgesia of an opioid peptide by glycosylation. (2001) (90)
- The effect of halogenation on blood–brain barrier permeability of a novel peptide drug☆ (1999) (90)
- CNS drug delivery: Opioid peptides and the blood-brain barrier (2006) (89)
- Effect of peptidases at the blood brain barrier on the permeability of enkephalin. (1994) (88)
- Alterations in blood-brain barrier ICAM-1 expression and brain microglial activation after lambda-carrageenan-induced inflammatory pain. (2006) (88)
- Assessment of an in vitro blood-brain barrier model using several [Met5]enkephalin opioid analogs. (1993) (85)
- Stabilization of ascorbic acid in human plasma, and its liquid-chromatographic measurement. (1988) (84)
- Tight junctions contain oligomeric protein assembly critical for maintaining blood–brain barrier integrity in vivo (2007) (83)
- Mannitol opening of the blood–brain barrier: regional variation in the permeability of sucrose, but not 86Rb+ or albumin (2004) (82)
- Occludin oligomeric assemblies at tight junctions of the blood–brain barrier are altered by hypoxia and reoxygenation stress (2009) (82)
- Disposition of mitoxantrone in cancer patients. (1985) (81)
- Doxepin's effects on chronic pain and depression: a controlled study. (1984) (78)
- Activation of PKC modulates blood-brain barrier endothelial cell permeability changes induced by hypoxia and posthypoxic reoxygenation. (2005) (76)
- Blood-brain barrier permeability and bioavailability of a highly potent and mu-selective opioid receptor antagonist, CTAP: comparison with morphine. (1997) (75)
- Modulation of cerebral microvascular permeability by endothelial nicotinic acetylcholine receptors. (2005) (75)
- Blood-to-central nervous system entry and stability of biphalin, a unique double-enkephalin analog, and its halogenated derivatives. (1996) (75)
- Passage of a δ‐Opioid Receptor Selective Enkephalin, [d‐Penicillamine2,5]Enkephalin, Across the Blood‐Brain and the Blood‐Cerebrospinal Fluid Barriers (1996) (74)
- Occludin oligomeric assembly at tight junctions of the blood‐brain barrier is disrupted by peripheral inflammatory hyperalgesia (2008) (74)
- Whole body and brain distribution of [3H]cyclic [D-Pen2,D-Pen5] enkephalin after intraperitoneal, intravenous, oral and subcutaneous administration. (1992) (73)
- P‐glycoprotein trafficking at the blood–brain barrier altered by peripheral inflammatory hyperalgesia (2012) (70)
- An Activated Protein C Analog With Reduced Anticoagulant Activity Extends the Therapeutic Window of Tissue Plasminogen Activator for Ischemic Stroke in Rodents (2012) (69)
- Rapid Group B Streptococci Screening Using a Real-Time Polymerase Chain Reaction Assay (2008) (68)
- Light microscopic autoradiographic visualization of [3H]-arginine vasopressin binding sites in rat brain. (1983) (66)
- Inflammatory Pain Signals an Increase in Functional Expression of Organic Anion Transporting Polypeptide 1a4 at the Blood-Brain Barrier (2011) (65)
- Phase 1 safety, tolerability and pharmacokinetics of 3K3A-APC in healthy adult volunteers. (2014) (63)
- Targeted Drug Delivery to Treat Pain and Cerebral Hypoxia (2013) (63)
- Distribution of insulin in trigeminal nerve and brain after intranasal administration (2019) (61)
- Differential neuroprotection and risk for bleeding from activated protein C with varying degrees of anticoagulant activity. (2009) (60)
- Pain and the blood-brain barrier: obstacles to drug delivery. (2003) (59)
- Comparative changes in the blood-brain barrier and cerebral infarction of SHR and WKY rats. (2007) (59)
- Targeting blood-brain barrier changes during inflammatory pain: an opportunity for optimizing CNS drug delivery. (2011) (59)
- Permeability of the blood-brain barrier to peptides: An approach to the development of therapeutically useful analogs (1992) (58)
- Transport of opioid peptides into the central nervous system. (1998) (58)
- Peptide fragments derived from the β-chain of hemoglobin (hemorphins) are centrally active in vivo (1989) (57)
- “Small Blood Vessels: Big Health Problems?”: Scientific Recommendations of the National Institutes of Health Workshop (2016) (57)
- Chronic inflammatory pain and the neurovascular unit: a central role for glia in maintaining BBB integrity? (2008) (57)
- Reoxygenation stress on blood-brain barrier paracellular permeability and edema in the rat. (2008) (56)
- Beta-endorphin and neurotensin stimulate in vitro clonal growth of human SCLC cells. (1989) (56)
- Nitric oxide mediates hypoxia-induced changes in paracellular permeability of cerebral microvasculature. (2004) (55)
- Preclinical safety and pharmacokinetic profile of 3K3A-APC, a novel, modified activated protein C for ischemic stroke. (2012) (55)
- Hypoxia‐inducible factor and nuclear factor kappa‐B activation in blood–brain barrier endothelium under hypoxic/reoxygenation stress (2005) (55)
- Fluorescence polarization immunoassay IV. Determination of phenytoin and phenobarbital in human serum and plasma. (1982) (55)
- An Activated Protein C Analog Stimulates Neuronal Production by Human Neural Progenitor Cells via a PAR1-PAR3-S1PR1-Akt Pathway (2013) (54)
- Functional Expression of P-glycoprotein and Organic Anion Transporting Polypeptides at the Blood-Brain Barrier: Understanding Transport Mechanisms for Improved CNS Drug Delivery? (2017) (54)
- Ectoenzymes as sites of peptide regulation. (1996) (53)
- Comparison of the Next-Generation Xpert MRSA/SA BC Assay and the GeneOhm StaphSR Assay to Routine Culture for Identification of Staphylococcus aureus and Methicillin-Resistant S. aureus in Positive-Blood-Culture Broths (2014) (53)
- Protection against hypoxia-induced blood-brain barrier disruption: changes in intracellular calcium. (2004) (53)
- Brain and Spinal Cord Distribution of Biphalin: Correlation with Opioid Receptor Density and Mechanism of CNS Entry (1997) (53)
- SR48692 is a neurotensin receptor antagonist which inhibits the growth of small cell lung cancer cells (2001) (52)
- Improved high-performance liquid chromatography of the new antineoplastic agents bisantrene and mitoxantrone. (1982) (52)
- Acetaminophen Modulates P-Glycoprotein Functional Expression at the Blood-Brain Barrier by a Constitutive Androstane Receptor–Dependent Mechanism (2013) (51)
- Effect of guanidino modification and proline substitution on the in vitro stability and blood-brain barrier permeability of endomorphin II. (2002) (51)
- Targeting transporters: Promoting blood–brain barrier repair in response to oxidative stress injury (2015) (51)
- Biphasic cytoarchitecture and functional changes in the BBB induced by chronic inflammatory pain (2006) (50)
- New frontiers in translational research in neuro-oncology and the blood-brain barrier: report of the tenth annual Blood-Brain Barrier Disruption Consortium Meeting. (2005) (49)
- Effects of Indomethacin and Meclofenamate on Renin Release and Renal Hemodynamic Function during Chronic Sodium Depletion in Conscious Dogs (1980) (49)
- Hypoxic Stress and Inflammatory Pain Disrupt Blood-Brain Barrier Tight Junctions: Implications for Drug Delivery to the Central Nervous System (2017) (49)
- High-performance liquid chromatographic analysis of biogenic amines in biological materials as o-phthalaldehyde derivatives. (1979) (48)
- Bioavailability of Ziconotide in brain: influx from blood, stability, and diffusion (2000) (48)
- Pharmacokinetics of 13-cis-retinoic acid in patients with advanced cancer. (1982) (46)
- P-glycoprotein trafficking as a therapeutic target to optimize CNS drug delivery. (2014) (46)
- Clinical Evaluation of the BD ProbeTec™ Chlamydia trachomatis Qx Amplified DNA Assay on the BD Viper™ System With XTR™ Technology (2011) (43)
- Metabolic stability and tumor inhibition of bombesin/GRP receptor antagonists (1992) (42)
- Tempol modulates changes in xenobiotic permeability and occludin oligomeric assemblies at the blood-brain barrier during inflammatory pain. (2012) (40)
- Motility effects of opioid peptides in dog intestine. (1982) (40)
- Disposition of mitoxantrone in patients. (1983) (40)
- P-glycoprotein Modulates Morphine Uptake into the CNS: A Role for the Non-steroidal Anti-inflammatory Drug Diclofenac (2014) (40)
- Enkephalin analog prodrugs: assessment of in vitro conversion, enzyme cleavage characterization and blood-brain barrier permeability. (1996) (40)
- Perivascular and Perineural Pathways Involved in Brain Delivery and Distribution of Drugs after Intranasal Administration (2019) (39)
- Identification and quantification of alpha-methylfentanyl in post mortem specimens. (1982) (38)
- Nociceptive inhibition prevents inflammatory pain induced changes in the blood–brain barrier (2008) (38)
- Stroke: development, prevention and treatment with peptidase inhibitors☆ (2000) (38)
- Clinical Evaluation of the Cepheid Xpert TV Assay for Detection of Trichomonas vaginalis with Prospectively Collected Specimens from Men and Women (2017) (36)
- Pharmacodynamic and pharmacokinetic characterization of poly(ethylene glycol) conjugation to met-enkephalin analog [D-Pen2, D-Pen5]-enkephalin (DPDPE). (2001) (35)
- Effect of λ-carrageenan-induced inflammatory pain on brain uptake of codeine and antinociception (2004) (33)
- Time-dependent sensitization of plasma beta-endorphin in community elderly with self-reported environmental chemical odor intolerance (1996) (32)
- Neurotensin elevates cytosolic calcium in small cell lung cancer cells (1989) (32)
- Neurotensin is Metabolized by Endogenous Proteases in Prostate Cancer Cell Lines (1998) (31)
- Assessment of Stereoselectivity of Trimethylphenylalanine Analogues of δ‐Opioid [D‐Pen2,D‐Pen5]‐Enkephalin (2000) (31)
- The entry of [D-penicillamine2,5]enkephalin into the central nervous system: saturation kinetics and specificity. (1997) (30)
- Protease inhibitors suppress in vitro growth of human small cell lung cancer (1993) (29)
- Pluronic P85 Block Copolymer Enhances Opioid Peptide Analgesia (2002) (29)
- High-performance liquid chromatographic analysis of in vitro central neuropeptide processing. (1985) (29)
- Pre-column derivatization and high-performance liquid chromatography of biogenic amines in blood of normal and malignant hyperthermic pigs. (1982) (29)
- Structure-activity relationships of a series of [D-Ala2]deltorphin I and II analogues; in vitro blood-brain barrier permeability and stability. (1997) (29)
- Processing and transfer of epidermal growth factor in developing rat jejunum and ileum (1990) (28)
- A specific enzyme assay for aminopeptidase M in rat brain. (1992) (27)
- Differential in vitro metabolism of β-endorphin in schizophrenia (1984) (27)
- Agonist and antagonist profiles of [D-Ala2,Glu4]deltorphin and its [Cys4]- and [Ser4]-substituted derivatives: further evidence of opioid delta receptor multiplicity. (1993) (26)
- Transport of the delta-opioid receptor agonist [D-penicillamine2,5] enkephalin across the blood-brain barrier involves transcytosis1. (1999) (25)
- Neurotensin may function as a regulatory peptide in small cell lung cancer (1991) (25)
- Inhibition of intestinal degradation of somatostatin by rat milk. (1990) (24)
- Differential effects of diabetes on rat choroid plexus ion transporter expression. (2003) (24)
- Physiology and Pathophysiology of the Blood-Brain Barrier (2012) (23)
- Multicenter Study Evaluating Performance of the Smart Group B Streptococcus (GBS) Assay Using an Enrichment Protocol for Detecting GBS Colonization in Patients in the Antepartum Period (2010) (23)
- Peptidases in the CNS: formation of biologically active, receptor-specific peptide fragments. (1993) (23)
- High-performance liquid chromatography of the provitamin A β-carotene in plasma (1983) (23)
- beta-Endorphin and its metabolites stimulate motility of the dog small intestine. (1983) (23)
- The proenkephalin A fragment, peptide E: central processing and CNS activity in vivo. (1985) (22)
- Effect of reduced flow on blood–brain barrier transport systems (2001) (22)
- Peptide targeting and delivery across the blood-brain barrier utilizing synthetic triglyceride esters: design, synthesis, and bioactivity. (1997) (22)
- Prohormone convertase and autocrine growth factor mRNAs are coexpressed in small cell lung carcinoma. (2000) (22)
- Transporter-Mediated Delivery of Small Molecule Drugs to the Brain: A Critical Mechanism That Can Advance Therapeutic Development for Ischemic Stroke (2020) (22)
- High performance liquid chromatography of pharmacologically active amines and peptides in biological materials. (1982) (21)
- Specificity of Neurotensin Metabolism by Regional Rat Brain Slices (1992) (21)
- Clinical Evaluation of the BD ProbeTec™ Neisseria gonorrhoeae Qx Amplified DNA Assay on the BD Viper™ System With XTR™ Technology (2012) (21)
- Modifications of the 4,4'-residues and SAR studies of Biphalin, a highly potent opioid receptor active peptide. (1998) (21)
- Centrally acting drugs alter in vitro β-endorphin processing in the rat (1984) (20)
- Metabolic half-life of somatostatin and peptidase activities are altered in Alzheimer's disease. (1992) (20)
- High performance liquid chromatography of a new anticancer drug, ADCA--physicochemical properties and pharmacokinetics. (1981) (20)
- Effect of lambda-carrageenan-induced inflammatory pain on brain uptake of codeine and antinociception. (2004) (20)
- Diclofenac Attenuates the Regional Effect of λ-Carrageenan on Blood-Brain Barrier Function and Cytoarchitecture (2008) (20)
- Alterations of Peptide Metabolism and Neuropeptidase Activity in Senile Dementia of the Alzheimer's Type a (1997) (20)
- HPLC, MS, and pharmacokinetics of melphalan, bisantrene and 13-cis retinoic acid. (1982) (19)
- [D-Pen2,4'-125I-Phe4,D-Pen5]enkephalin: a selective high affinity radioligand for delta opioid receptors with exceptional specific activity. (1991) (19)
- Haloperidol and apomorphine differentially affect neuropeptidase activity. (1996) (19)
- Proenkephalin A-derived peptide E and its fragments alter opioid contractility in the small intestine. (1990) (18)
- P-glycoprotein traffics from the nucleus to the plasma membrane in rat brain endothelium during inflammatory pain (2016) (18)
- Loss of Blood-Brain Barrier Integrity in a KCl-Induced Model of Episodic Headache Enhances CNS Drug Delivery (2018) (18)
- The effect of mycoplasma on the autocrine stimulation of human small cell lung cancer in vitro by bombesin and beta-endorphin. (1989) (17)
- Identification of P‐glycoprotein co‐fractionating proteins and specific binding partners in rat brain microvessels (2015) (17)
- In vitro stability of some reduced peptide bond pseudopeptide analogues of dynorphin A (1995) (17)
- Distribution and pharmacokinetics of a potent peptide antagonist of parathyroid hormone and parathyroid hormone-related protein in the rat. (1995) (17)
- Differential modulation of prohormone convertase mRNA by second messenger activators in two cholecystokinin-producing cell lines (1996) (16)
- Insulin enhancement of opioid peptide transport across the blood-brain barrier and assessment of analgesic effect. (2000) (16)
- THE EFFECT OF GLYCOSYLATION ON THE UPTAKE OF AN ENKEPHALIN ANALOGUE INTO THE CENTRAL NERVOUS SYSTEM (1996) (16)
- Identification of β-endorphin-(6–17) as the principal metabolite of des-tyrosine-γ-endorphin (DTγE) in vitro and assessment of its activity in neurotransmitter receptor binding assays (1982) (16)
- Regional Metabolism of Met‐Enkephalin and Cholecystokinin on Intact Rat Brain Slices: Characterization of Specific Peptidases (1995) (16)
- Development of neuropeptide drugs that cross the blood-brain barrier (2005) (16)
- Development and Maintenance of the Blood–Brain Barrier (2017) (16)
- Regional differences in gastrointestinal processing and absorption of epidermal growth factor in suckling rats. (1991) (15)
- Neuropeptide metabolism on intact, regional brain slices: effect of dopaminergic agents on substance P, cholecystokinin and Met-enkephalin degradation. (1995) (15)
- Analysis of polyamines and acetyl derivatives by a single automated amino acid analyzer technique. (1983) (15)
- Improved analogs and novel delivery systems for somatostatin octapeptides. (1996) (15)
- Acute administration of neuroleptics decreases neurotensin metabolism on intact, regional rat brain slices. (1994) (14)
- Modulation of Opioid Transport at the Blood-Brain Barrier by Altered ATP-Binding Cassette (ABC) Transporter Expression and Activity (2018) (14)
- [125I-Tyr1]biphalin binding to opioid receptors of rat brain and NG108-15 cell membranes. (1998) (14)
- Conjugation of low molecular weight poly(ethylene glycol) to biphalin enhances antinociceptive profile. (2003) (14)
- [L-Ala3]DPDPE: a new enkephalin analog with a unique opioid receptor activity profile. Further evidence of delta-opioid receptor multiplicity. (1994) (14)
- 17-β-Estradiol induces spreading depression and pain behavior in alert female rats (2017) (14)
- Methicillin-Resistant Staphylococcus aureus (MRSA) Nasal Real-Time PCR: A Predictive Tool for Contamination of the Hospital Environment (2015) (14)
- Quantitative analysis of prostaglandins in cell culture medium by high-resolution gas chromatography with electron-capture detection. (1984) (14)
- Bone morphogenetic protein-9 increases the functional expression of organic anion transporting polypeptide 1a4 at the blood–brain barrier via the activin receptor-like kinase-1 receptor (2017) (14)
- Subchronic haloperidol administration decreases aminopeptidase N activity and [Met5]enkephalin metabolism in rat striatum and cortex. (1996) (13)
- Urinary polyamines as markers of cardiac allograft rejection. A clinical evaluation. (1988) (13)
- Volume and composition of hand sweat of White and Black men and women in desert walks. (1983) (13)
- 8 – Methods of Measuring Neuropeptides and Their Metabolism (1991) (13)
- Neuropeptide processing in regional brain slices: effect of conformation and sequence. (1990) (13)
- Oxidative Stress Increases Blood—Brain Barrier Permeability and Induces Alterations in Occludin during Hypoxia—Reoxygenation (2011) (12)
- Isolation and characterization of in vitro central beta-endorphin metabolism in schizophrenia. (1983) (12)
- Viability of microvascular endothelial cells to direct exposure of formalin, lambda-carrageenan, and complete Freund's adjuvant. (2002) (12)
- Chronic treatment with neuroleptics alters neutral endopeptidase 24.11 activity in rat brain regions (1993) (12)
- Neuroleptic drug treatment alters in vitro central neurotensin metabolism (1987) (12)
- Chronic morphine exposure potentiates p-glycoprotein trafficking from nuclear reservoirs in cortical rat brain microvessels (2018) (12)
- Specific regional differences of in vitro beta-endorphin metabolism in schizophrenics. (1986) (12)
- Action of Three Ectopeptidases on Corticotropin-Releasing Factor: Metabolism and Functional Aspects (2003) (12)
- Characterization of in vitro proteolytic processing of β-endorphin by reversed-phase HPLC (1984) (11)
- Unexpected antinociceptive potency of cyclic [D-Tca1]CTAP: potential for a novel mechanism of action. (1993) (11)
- Erratum: Oxidative stress increases blood-brain barrier permeability and induces alterations in occludin during hypoxia-reoxygenation (Journal of Cerebral Blood Flow and Metabolism (2010) 30 (1625-1636) DOI: 10.1038/jcbfm.2010.29) (2011) (10)
- Acute pain alters P-glycoprotein-containing protein complexes in rat cerebral microvessels: Implications for P-glycoprotein trafficking (2018) (10)
- Assessment of stereoselectivity of trimethylphenylalanine analogues of delta-opioid [D-Pen(2),D-Pen(5)]-enkephalin. (2000) (10)
- Doxepin??s effects on chronic pain and depression: a controlled study (1984) (10)
- The developing gastrointestinal tract and milk-borne epidermal growth factor. (1991) (10)
- Fate of intraduodenally administered somatostatin in rats in vivo (1993) (10)
- Peptides at the blood brain barrier: Knowing me knowing you (2015) (9)
- Comparative pharmacology of mitoxantrone and bisantrene (1982) (9)
- Effect of dopaminergic drugs on processing and degradative neuropeptidase mRNA in rat frontal cortex and caudate-putamen (1997) (9)
- Endorphins and the central inhibition of urinary bladder motility (1984) (9)
- Sensitive and quantitative determination of plasma doxepin and desmethyldoxepin in chronic pain patients by gas chromatography and mass spectrometry. (1983) (9)
- Doxepin Effects on Chronic Pain and Depression: A Controlled Study (1987) (8)
- Multicenter Evaluation of NeuMoDx Group B Streptococcus Assay on the NeuMoDx 288 Molecular System (2018) (8)
- Positional effects in the neprilysin (neutral endopeptidase) reaction. (1994) (8)
- Blood–Brain Barrier Transporters: Opportunities for Therapeutic Development in Ischemic Stroke (2022) (8)
- Influence of the 3K3A‐activated protein C variant on the plasma clot lysis activity of t‐PA and of t‐PA on the variant's anticoagulant activity (2013) (8)
- Repressive and defensive coping styles predict resting plasma endorphin levels in the elderly (1998) (7)
- Processing, release and metabolism of cholecystokinin in SK-N-MCIXC cells (1993) (7)
- A non-equilibrium 24-hour vasopressin radioimmunoassay: development and basal levels in the rat brain (1983) (7)
- Effect of milk on somatostatin degradation in suckling rat jejunum in vivo. (1999) (7)
- Mechanisms of Endothelial Injury and Blood–Brain Barrier Dysfunction in Stroke (2017) (7)
- Endogenous levels of β-carotene in human buccal mucosa cells by reversed-phase high-performance liquid chromatography (1990) (7)
- Stroke Treatment With PAR-1 Agents to Decrease Hemorrhagic Transformation (2021) (6)
- Ontogenic differences in the inhibition of gastric acid secretion by epidermal growth factor. (1993) (6)
- Targeting organic cation transporters at the blood-brain barrier to treat ischemic stroke in rats (2022) (6)
- Transport Properties of Statins by Organic Anion Transporting Polypeptide 1A2 and Regulation by Transforming Growth Factor-β Signaling in Human Endothelial Cells (2020) (6)
- Pharmacology of the blood brain barrier : targeting CNS disorders (2014) (6)
- Gabapentin and Diclofenac Reduce Opioid Consumption in Patients Undergoing Tonsillectomy: A Result of Altered CNS Drug Delivery? (2013) (6)
- Antihypertensive effects of parenteral nicardipine alone and in combination with captopril (1987) (6)
- The role of serum and tissue pharmacology studies in the design and interpretation of chemoprevention trials. (1989) (6)
- Pharmacokinetics and Phase I Trial of Retinol and 13-cis-Retinoic Acid (1983) (6)
- The proenkephalin A fragment metorphamide shows supraspinal and spinal opioid activity in vivo (1985) (6)
- Novel somatostatin analogs for the treatment of acromegaly and cancer exhibit improved in vivo stability and distribution. (1998) (5)
- Elevation of plasma beta-endorphin levels of shy elderly in response to novel laboratory experiences. (1997) (5)
- Detection of Human Papillomavirus L1 Protein in Condylomata Acuminata From Various Anatomical Sites (1994) (5)
- Changes in opioid receptor selectivity following processing of peptide E: effect on gut motility. (1991) (5)
- Regulation of CCK mRNA in the human neuroepithelioma cell line SK‐N‐MCIXC in response to second messenger activators (1993) (5)
- Organic Cation Transporter (OCT/OCTN) Expression at Brain Barrier Sites: Focus on CNS Drug Delivery. (2021) (5)
- Functional NHE1 expression is critical to blood brain barrier integrity and sumatriptan blood to brain uptake (2019) (5)
- Isolation and characterization of in vitro endorphin metabolism in the brain. (1982) (5)
- Hormonal, hematologic, and other biochemical constituents in the burro, Equus asinus. (1978) (4)
- Molecular modulation of the blood-brain barrier during stroke (2005) (4)
- A method for the simultaneous measurement of the new anthracycline derivative 4′ -deoxydoxorubicin and its metabolites by reversed phase liquid chromatography (2004) (4)
- Urinary polyamines are noninvasive markers of heart allograft rejection. (1987) (4)
- High-performance liquid chromatography of the provitamin A beta-carotene in plasma. (1983) (4)
- Synthesis of [D-Ala2,4'-125I-Phe3,Glu4]deltorphin and characterization of its delta opioid receptor binding properties. (1992) (3)
- The ontogeny of enzymes involved in post-translational processing and metabolism of neuropeptides. (1994) (3)
- A study of the metabolism of des-tyrosine-gamma-endorphin using an improved HPLC system. (1982) (3)
- Conformationally constrained peptide drugs targeted at the blood-brain barrier. (1995) (3)
- Antibodies and Recombinant Cytokines (2005) (3)
- Molecular variants of epidermal growth factor in malignant astrocytoma (1996) (3)
- Partition of Body Fluids in the Burro (1978) (3)
- Processing of beta-endorphin in the dog intestine: regional specificity. (1983) (3)
- Serotonin-induced vascular permeability is mediated by transient receptor potential vanilloid 4 in the airways and upper gastrointestinal tract of mice (2021) (3)
- Modulation of Prohormone Convertase mRNA by Second Messenger Activators and Drugs (1996) (3)
- Effect of temperature stress on circulating biogenic amines in bovine. (1984) (3)
- The proenkephalin A fragment peptide E is metabolized centrally to a novel peptide with opioid activity. (1987) (3)
- Chronic haloperidol and chlorpromazine treatment alters in vitro beta-endorphin metabolism in rat brain. (1990) (3)
- Haloperidol, chlorpromazine and apomorphine alter central regional neuropeptidase activity (1990) (3)
- Ethanol treatment alters β-endorphin metabolism by purified synaptosomal plasma membranes (1987) (3)
- Identification of beta-endorphin-6(16-17) as the principal metabolite of des-tyrosin-gamma-endorphin (DTgammaE) in vitro and assessment of its activity in neurotransmitter receptor binding assays. (1982) (2)
- The pro-enkephalin A derivative, peptide E, is centrally processed to active fragments. (1984) (2)
- Endorphin metabolism in brain and gut: Regional specificity (1983) (2)
- Structure Dependent Differential Modulation of Aβ Fibrillization by Selenadiazole-Based Inhibitors. (2021) (2)
- Value of urinary polyamines as noninvasive markers of cardiac allograft rejection in the dog. (1988) (2)
- CNS Delivery of Peptides Across the BBB Using the Dual-Artery In Situ Brain Perfusion Model (2010) (2)
- Differential in vitro metabolism of beta-endorphin in schizophrenia. (1984) (2)
- Transport Mechanisms at the Blood–Brain Barrier and in Cellular Compartments of the Neurovascular Unit: Focus on CNS Delivery of Small Molecule Drugs (2022) (2)
- Regional specificity of beta-endorphin metabolism in brain slices of the rat. (1988) (2)
- Regulation of Blood-Brain Barrier Transporters by Transforming Growth Factor-β/Activin Receptor-Like Kinase 1 Signaling: Relevance to the Brain Disposition of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Inhibitors (i.e., Statins) (2022) (2)
- Structure-Activity Relationships of a Series of [ DAla 2 ] Deltorphin I and II Analogues ; in Vitro Blood-Brain Barrier Permeability and Stability 1 (1997) (1)
- High-Performance Liquid-ChromatographicSeparation and Fluorescence Measurement of Biogenic Amines in Plasma , Urine , and Tissue 1 (2004) (1)
- Cationized deltorphin analogues: Potent and selective ligands for delta opiate receptors (1994) (1)
- Design, synthesis and conformation in chi space for developing selective peptides for types and subtypes of receptors (1995) (1)
- PHYSIOLOGY AND PATHOPHYSIOLOGY OF THE BLOOD BRAIN BARRIER: P-glycoprotein and occludin trafficking as therapeutic targets to optimize CNS drug delivery (2012) (1)
- Role of Sex Hormones in Regulation of Sodium‐Proton Exchanger NHE1: Implications for Migraine (2018) (1)
- Clinical Toxicology Pharmacokinetics of 13-Cis-Retinoic Acid Administered Chronically at Low Doses Expected for Cancer Chemoprevention Trials (1986) (1)
- Central metabolism of beta-endorphin in different species of temperature acclimated rodents. (1986) (1)
- Modulation of CCK mRNA in cell lines in response to isoproterenol and retinoic acid (1995) (1)
- A sensitive and specific procedure for the analysis of β-carotene in human skin (1989) (1)
- [125I]SNF 8702: A selective radioligand for CCKB receptors (1995) (1)
- Chapter 232 – Opioid Peptides (2013) (1)
- Intake, Digestibility and Energy Utilization of Corrugated Paper Diets* (1987) (1)
- High-Dose Acetaminophen Alters the Integrity of the Blood–Brain Barrier and Leads to Increased CNS Uptake of Codeine in Rats (2022) (1)
- Research report Improved bioavailability to the brain of glycosylated Met-enkephalin (2000) (1)
- Design of peptides and peptidomimetics for delta and kappa opioid receptor subtypes (1994) (1)
- In vivo and in vitro metabolism of the new anticancer drug bisantrene (2004) (1)
- Endogenous levels of beta-carotene in human buccal mucosa cells by reversed-phase high-performance liquid chromatography. (1990) (1)
- Serotonin-induced vascular permeability is mediated by transient receptor potential vanilloid 4 in the airways and upper gastrointestinal tract of mice. (2021) (0)
- Centrally acting drugs alter in vitro beta-endorphin processing in the rat. (1984) (0)
- In vitro central β-endorphin metabolism in schizophrenia: Regional specificity (1985) (0)
- Functional Expression of P-glycoprotein and Organic Anion Transporting Polypeptides at the Blood-Brain Barrier: Understanding Transport Mechanisms for Improved CNS Drug Delivery? (2017) (0)
- Demonstration and partial characterization of a bovine cerebral cortical factor which interacts competitively at the benzodiazepine receptor. (1983) (0)
- Abstract TP205: Organic Anion Transporting Polypeptides: Endogenous Blood-brain Barrier Transporters That Are Required For Statins To Exert Neuroprotective Effects In Ischemic Stroke (2023) (0)
- Peptides and the Blood-Brain Barrier: Enhancing Peptide Bioavailability to the Brain (2004) (0)
- Proenkephalin a fragments stimulate motility of the canine isolated intestine (1984) (0)
- Separation and quantitation of biogenic amines in plasma and tissue by high performance liquid chromatography (1978) (0)
- FluorescencePolarizationlmmunoassayIV. Determinationof Phenytoinand Phenobarbitalin HumanSerum and Plasma (2004) (0)
- Isolation, characterization and motility effects of β-LPH fragments in the isolated perfused intestine (1982) (0)
- Glial Support of Blood–Brain Barrier Integrity: Molecular Targets for Novel Therapeutic Strategies in Stroke (2016) (0)
- Protease inhibitors suppress in vitro clonal growth of human small cell lung cancer (1990) (0)
- Hypoxic Stress and Inflammatory Pain Disrupt Blood-Brain Barrier Tight Junctions: Implications for Drug Delivery to the Central Nervous System (2017) (0)
- Peptide hormones as prohormones: Processing, biological activity, pharmacology: Edited by Jean Martinez, Ellis Horwood, 1989. £45.00 (x + 354 pages) ISBN 0 7458 0222 2 (1989) (0)
- Design of Peptides and Peptidomimetics That Are Selective, Stable and Can Cross Membrane Barriers (1997) (0)
- Glycosylation improves the blood-brain barrier penetration of a linear opioid peptide analog (1999) (0)
- Opioid peptide prodrugs: In vitro blood-brain barrier permeability and conversion rates (1998) (0)
- The amidated proenkephalin A fragment metorphamide shows selective opioid activity in vivo (1985) (0)
- Blood-brain barrier in health and disease (2008) (0)
- Hypoxia and post‐hypoxic reoxygenation alter mRNA expression of claudin‐1,‐3, and ‐5 in endothelial cells of the BBB (2006) (0)
- Guanidino cationization effects on the blood-brain barrier permeability, in vitro stability and receptor binding of endomorphins (1999) (0)
- ß-Endorphin is Metabolized in Vitro by Human Small Cell Lung Cancer to γ-Endorphin Which Stimulates Clonal Growth (1993) (0)
- Time-course administration of neuroleptics decreases regional neurotensin metabolism in intact rat brain slices (1993) (0)
- Transport Properties of Statins by OATP1A2 and Regulation by Transforming Growth Factor- (TGF- ) Signaling in Human (2020) (0)
- Heat Shock Proteins (1984) (0)
- Opiate Peptides and the Blood—Brain Barrier (2006) (0)
- 544. PICKUP: Pneumonia in the Immunocompromised - Use of the Karius Test for Detection of Undiagnosed Pathogens (2022) (0)
- Abstract TP121: Organic Anion Transporting Polypeptide (Oatp)-Mediated Transport is Required for Statin-Induced Neuroprotection: A Role for Blood-Brain Barrier Transporters in Stroke Treatment (2020) (0)
- Distribution of insulin in trigeminal nerve and brain after intranasal administration (2019) (0)
- for Blood-Brain Barrier Disruption After Stroke Calcium Modulation of Adherens and Tight Junction Function : A Potential Mechanism (2002) (0)
- Synthesis, opioid activities and binding affinities of dynorphin A analogues with position-3 conformational constraints: New insights into requirements for κ receptors (1995) (0)
- High Resolution Multiplex Confocal Imaging of the Neurovascular Unit in Health and Experimental Ischemic Stroke (2023) (0)
- INTRAVENOUSLY ADMINISTERED 125I-EGF IS SECRETED INTO BILE AND LUMEN OF SUCKLING RAT STOMACH AND INTESTINE (1990) (0)
- 3K3A-Activated Protein C Variant Does Not Interfere With the Plasma Clot Lysis Activity of Tenecteplase (2020) (0)
- Methods to Study Drug Uptake at the Blood-Brain Barrier Following Experimental Ischemic Stroke: In Vitro and In Vivo Approaches. (2023) (0)
- Processing of the proenkephalin in a fragment peptide E by regions of the small intestine (1985) (0)
- Respiratory activity and metabolic rate of burros, Equus asinus: Effect of age (1978) (0)
- Erratum to Chronic Inflammation Pain and the Neurovascular Unit: A Central Role for Glia in Maintaining BBB Integrity (Curr Pharm Des, (2008), 14, (1625-1643)) (2011) (0)
- Effect of acute heat and cold exposure on biogenic amines in cattle (1979) (0)
- (143) Transient Decreases in Blood-Brain Barrier Integrity Correspond with Facial Allodynia Duration in a Model of Migraine with Aura (2017) (0)
- Clinical Evaluation of the Great Basin Clostridium difficile Assay and the BD GeneOhm™ Cdiff Assay for the Rapid Detection of Clostridium difficile toxin B gene in Fecal Specimens (2012) (0)
- 543. Perceived Ease of Use and Operator Performance of a rapid Multiplex PCR Diagnostic System in a Near Patient Setting (2022) (0)
- 17: Comparative analysis of ESwab™ and standard collection systems for nugent scoring in the diagnosis of bacterial vaginosis (2015) (0)
- Surprisingly potent and selective 3-position analogs of DPDPE for the δ opioid receptor (1993) (0)
- Ex Vivo Fluorometric Analysis of Efflux Transporters in Rat Choroid Plexus (2006) (0)
- 534. Evaluation of a Rapid Multiplex PCR Diagnostic Device for the Detection of Microorganisms from Nasopharyngeal and Throat Swab Specimens in the Near Patient Setting (2022) (0)
- Second Messenger Activators Regulate CCK mRNA in the Human Neuroepithelioma Cell Line SK‐N‐MCIXC a (1994) (0)
- O22 Performance of the BD max™ CT/GC/TV assay for detection of chlamydia, gonorrhoea and trichomonas (2015) (0)
- 288. IGA ANTIBODY TO TISSUE TRANSGLUTAMINASE IS A HIGHLY SENSITIVE PREDICTOR OF ADULT ONSET COELIAC DISEASE IN CLINICAL PRACTICE (2001) (0)
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